Drug

Lisdexamfetamine Dimesylate

1,147 flagged reaction(s) · 121,022 total co-reports · max PRR 807.9

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Rhesus Incompatibility	68	807.9	809.6	signal
2	Amphetamines Negative	28	705.3	705.9	signal
3	Adulterated Product	28	108.8	108.9	signal
4	Change In Sustained Attention	43	108.3	108.4	signal
5	Disseminated Mycobacterium Avium Complex Infection	26	89.0	89.0	signal
6	Steroid Dependence	102	87.2	87.4	signal
7	Catarrh	102	82.8	83.0	signal
8	Negativism	86	81.3	81.5	signal
9	Dermatillomania	63	77.3	77.5	signal
10	Onychophagia	29	75.5	75.5	signal
11	Inability To Afford Medication	1,012	73.3	75.6	signal
12	Jaw Clicking	19	67.2	67.3	signal
13	Amphetamines Positive	66	61.0	61.1	signal
14	Conduct Disorder	17	56.3	56.4	signal
15	Trichotillomania	46	54.0	54.1	signal
16	Premenstrual Dysphoric Disorder	15	51.1	51.1	signal
17	Product Availability Issue	1,574	48.2	50.6	signal
18	Educational Problem	112	45.7	45.8	signal
19	Binge Eating	71	45.2	45.3	signal
20	Tic	360	45.1	45.5	signal
21	Burns Second Degree	111	43.3	43.4	signal
22	Urine Amphetamine Positive	21	43.1	43.1	signal
23	Drug Effect Variable	72	42.7	42.8	signal
24	Drug Effect Increased	181	38.2	38.4	signal
25	Intentional Self-injury	1,089	36.4	37.6	signal
26	Suspected Product Tampering	27	33.5	33.6	signal
27	Cryptosporidiosis Infection	26	33.2	33.2	signal
28	Disturbance In Social Behaviour	116	32.9	33.0	signal
29	Insurance Issue	722	32.6	33.3	signal
30	Impulsive Behaviour	172	30.6	30.8	signal
31	Oppositional Defiant Disorder	18	30.1	30.2	signal
32	Product Tampering	78	29.0	29.1	signal
33	Compulsive Hoarding	14	28.8	28.8	signal
34	Penis Injury	15	27.5	27.5	signal
35	Social Anxiety Disorder	27	27.3	27.3	signal
36	Attention Deficit Hyperactivity Disorder	170	27.3	27.4	signal
37	Logorrhoea	141	26.6	26.7	signal
38	Hypermetabolism	21	26.6	26.6	signal
39	Therapeutic Product Effect Variable	151	26.3	26.4	signal
40	Theft	26	25.8	25.8	signal
41	Job Dissatisfaction	25	25.6	25.6	signal
42	Abdominal Lymphadenopathy	33	25.5	25.6	signal
43	Alcohol Poisoning	101	25.3	25.3	signal
44	Breech Presentation	47	24.8	24.8	signal
45	Executive Dysfunction	18	23.1	23.1	signal
46	Product Physical Issue	695	23.1	23.5	signal
47	Compulsions	22	22.2	22.3	signal
48	Sleep-related Eating Disorder	30	21.1	21.1	signal
49	Hypopnoea	109	20.8	20.8	signal
50	Distractibility	36	20.6	20.6	signal
51	Attention Deficit/hyperactivity Disorder	91	18.3	18.3	signal
52	Cataplexy	39	17.9	17.9	signal
53	Product Administration Interrupted	205	17.5	17.6	signal
54	Somatic Symptom Disorder	28	17.0	17.0	signal
55	Pre-existing Condition Improved	162	16.8	16.9	signal
56	Postural Orthostatic Tachycardia Syndrome	33	16.5	16.5	signal
57	Flat Affect	57	16.4	16.4	signal
58	Self-destructive Behaviour	18	15.7	15.7	signal
59	Autism Spectrum Disorder	131	15.7	15.7	signal
60	Hepatitis Viral	19	15.5	15.5	signal
61	Disturbance In Attention	1,256	15.2	15.7	signal
62	Substance Use	35	14.8	14.8	signal
63	Psychotic Behaviour	23	14.7	14.7	signal
64	Narcolepsy	42	14.5	14.5	signal
65	Bruxism	116	14.0	14.1	signal
66	Therapeutic Response Changed	132	13.8	13.9	signal
67	Claustrophobia	23	13.8	13.8	signal
68	Jaundice Neonatal	40	13.7	13.8	signal
69	Drug Diversion	120	13.7	13.7	signal
70	Antisocial Behaviour	21	13.6	13.6	signal
71	Dissociation	157	13.6	13.6	signal
72	Drug Screen Negative	36	13.3	13.3	signal
73	Tachyphrenia	66	12.4	12.4	signal
74	Foetal Distress Syndrome	40	12.3	12.3	signal
75	Emotional Poverty	33	12.2	12.2	signal
76	Psychomotor Hyperactivity	307	12.0	12.1	signal
77	Intentional Overdose	1,137	11.6	12.0	signal
78	Sleep Paralysis	26	11.5	11.5	signal
79	Inappropriate Affect	28	11.4	11.4	signal
80	Mast Cell Activation Syndrome	22	10.8	10.8	signal
81	Drug Tolerance	84	10.7	10.8	signal
82	Prescribed Overdose	314	10.5	10.6	signal
83	Loss Of Employment	49	10.4	10.4	signal
84	Oral Administration Complication	15	10.4	10.4	signal
85	Parosmia	119	10.2	10.3	signal
86	Bronchiectasis	104	10.1	10.2	signal
87	Blood Hiv Rna Increased	28	10.1	10.1	signal
88	Performance Status Decreased	72	10.0	10.0	signal
89	Social Avoidant Behaviour	89	9.9	10.0	signal
90	Disturbance In Sexual Arousal	14	9.9	9.9	signal
91	Affect Lability	145	9.7	9.8	signal
92	Anger	503	9.6	9.7	signal
93	Weight Gain Poor	34	9.5	9.5	signal
94	Enuresis	59	9.5	9.5	signal
95	Hostility	37	9.3	9.3	signal
96	Impatience	27	9.3	9.3	signal
97	Obsessive Thoughts	26	9.3	9.3	signal
98	Growth Retardation	42	9.2	9.2	signal
99	Intrusive Thoughts	16	9.2	9.2	signal
100	Drug Effect Decreased	766	9.1	9.3	signal
101	Rhinitis	113	9.1	9.1	signal
102	Gingival Pain	111	9.0	9.0	signal
103	Frustration Tolerance Decreased	111	8.9	9.0	signal
104	Bipolar Disorder	151	8.9	9.0	signal
105	Pulse Abnormal	33	8.8	8.8	signal
106	Cardiac Murmur	118	8.8	8.8	signal
107	Initial Insomnia	137	8.7	8.7	signal
108	Obsessive-compulsive Disorder	108	8.7	8.7	signal
109	Stress At Work	15	8.6	8.6	signal
110	Disorganised Speech	24	8.6	8.6	signal
111	Terminal Insomnia	23	8.6	8.6	signal
112	Impulse-control Disorder	27	8.5	8.5	signal
113	Impaired Quality Of Life	188	8.4	8.5	signal
114	Irritability	783	8.4	8.6	signal
115	Somnambulism	85	8.3	8.4	signal
116	Obstructive Sleep Apnoea Syndrome	18	8.3	8.3	signal
117	Violence-related Symptom	20	8.3	8.3	signal
118	Aggression	639	8.2	8.4	signal
119	Feeling Jittery	241	8.2	8.2	signal
120	Paranoia	218	8.1	8.2	signal
121	Seizure Like Phenomena	21	8.1	8.1	signal
122	Hangover	44	8.0	8.0	signal
123	Drug Effect Less Than Expected	175	8.0	8.1	signal
124	Bipolar I Disorder	27	8.0	8.0	signal
125	Libido Increased	25	8.0	8.0	signal
126	Suicidal Behaviour	51	7.9	7.9	signal
127	Apathy	176	7.8	7.9	signal
128	Hypersexuality	22	7.7	7.7	signal
129	Self-injurious Ideation	50	7.7	7.7	signal
130	Feeling Of Despair	55	7.6	7.6	signal
131	Depersonalisation/derealisation Disorder	19	7.6	7.6	signal
132	Brain Fog	171	7.6	7.6	signal
133	Hyperphagia	45	7.3	7.3	signal
134	Abnormal Behaviour	452	7.3	7.4	signal
135	Abnormal Sleep-related Event	15	7.3	7.3	signal
136	Tinea Pedis	18	7.3	7.3	signal
137	Hunger	151	7.2	7.3	signal
138	Therapeutic Response Shortened	354	7.2	7.2	signal
139	Mania	182	7.1	7.2	signal
140	Personality Change	103	7.1	7.1	signal
141	Hyperacusis	41	7.1	7.1	signal
142	Euphoric Mood	113	7.1	7.1	signal
143	Generalised Anxiety Disorder	16	7.0	7.0	signal
144	Suspected Product Quality Issue	19	6.9	6.9	signal
145	Post-traumatic Stress Disorder	72	6.9	6.9	signal
146	Affective Disorder	84	6.9	6.9	signal
147	Impaired Work Ability	228	6.9	6.9	signal
148	Crying	381	6.7	6.8	signal
149	Drug Titration Error	27	6.7	6.7	signal
150	Underweight	20	6.6	6.6	signal
151	Excessive Eye Blinking	15	6.5	6.5	signal
152	Energy Increased	59	6.4	6.4	signal
153	Snoring	37	6.3	6.3	signal
154	Nasal Septum Deviation	19	6.3	6.3	signal
155	Daydreaming	15	6.3	6.3	signal
156	Sleep Deficit	20	6.2	6.2	signal
157	Appetite Disorder	63	6.2	6.2	signal
158	Suicidal Ideation	878	6.2	6.3	signal
159	Negative Thoughts	28	6.1	6.1	signal
160	Exposure Via Breast Milk	37	6.1	6.1	signal
161	Depressive Symptom	33	6.0	6.1	signal
162	Self Injurious Behaviour	29	6.0	6.0	signal
163	Homicidal Ideation	38	6.0	6.0	signal
164	Hypomania	34	5.9	5.9	signal
165	Food Interaction	16	5.9	5.9	signal
166	Social Problem	37	5.7	5.8	signal
167	Abnormal Loss Of Weight	60	5.7	5.7	signal
168	Loss Of Personal Independence In Daily Activities	421	5.7	5.8	signal
169	Product Quality Issue	1,191	5.7	5.9	signal
170	Mood Altered	239	5.7	5.7	signal
171	Emotional Disorder	270	5.6	5.6	signal
172	Behaviour Disorder	46	5.6	5.6	signal
173	Drug Administered To Patient Of Inappropriate Age	63	5.6	5.6	signal
174	Sleep Apnoea Syndrome	165	5.6	5.6	signal
175	Physical Assault	18	5.5	5.5	signal
176	Product Substitution Issue	495	5.5	5.6	signal
177	Drug Effect Delayed	39	5.5	5.5	signal
178	Gambling Disorder	23	5.5	5.5	signal
179	Psychotic Disorder	250	5.4	5.5	signal
180	Depressed Mood	442	5.4	5.5	signal
181	Sedation	217	5.4	5.4	signal
182	Hyperreflexia	29	5.3	5.3	signal
183	Drug Screen Positive	65	5.3	5.3	signal
184	Yawning	22	5.3	5.3	signal
185	Mood Swings	262	5.3	5.3	signal
186	Compulsive Shopping	17	5.3	5.3	signal
187	Electric Shock Sensation	22	5.3	5.3	signal
188	Premature Delivery	130	5.2	5.2	signal
189	Clumsiness	22	5.1	5.2	signal
190	Product Formulation Issue	52	5.1	5.1	signal
191	Hallucinations, Mixed	33	5.0	5.0	signal
192	Increased Appetite	146	5.0	5.0	signal
193	Dysphemia	34	5.0	5.0	signal
194	Thinking Abnormal	144	4.9	5.0	signal
195	Craniocerebral Injury	23	4.9	4.9	signal
196	Inappropriate Schedule Of Drug Administration	553	4.9	5.0	signal
197	Anorexia	100	4.9	4.9	signal
198	Hallucination, Auditory	119	4.8	4.8	signal
199	Therapeutic Reaction Time Decreased	22	4.8	4.8	signal
200	Food Craving	37	4.8	4.8	signal
201	Staring	18	4.8	4.8	signal
202	Mydriasis	95	4.8	4.8	signal
203	Trismus	38	4.7	4.7	signal
204	Screaming	47	4.7	4.7	signal
205	Viral Mutation Identified	27	4.7	4.7	signal
206	Therapeutic Response Unexpected	325	4.6	4.7	signal
207	Tearfulness	31	4.6	4.6	signal
208	Concussion	55	4.6	4.6	signal
209	Agitation	521	4.5	4.6	signal
210	Product Use Issue	1,319	4.5	4.7	signal
211	Derealisation	15	4.5	4.5	signal
212	Temporomandibular Joint Syndrome	19	4.5	4.5	signal
213	Panic Reaction	50	4.5	4.5	signal
214	Withdrawal Syndrome	290	4.4	4.4	signal
215	Panic Attack	250	4.4	4.4	signal
216	No Adverse Event	1,200	4.3	4.5	signal
217	Near Death Experience	22	4.3	4.3	signal
218	Feeling Drunk	50	4.3	4.3	signal
219	Neurological Symptom	38	4.3	4.3	signal
220	Major Depression	49	4.3	4.3	signal
221	Synovial Cyst	31	4.3	4.3	signal
222	Menopause	17	4.3	4.3	signal
223	Poor Quality Product Administered	67	4.2	4.2	signal
224	Restless Legs Syndrome	119	4.2	4.2	signal
225	Sinus Pain	15	4.2	4.2	signal
226	Swollen Tongue	203	4.2	4.2	signal
227	Personality Disorder	17	4.1	4.1	signal
228	Gastric Bypass	14	4.1	4.1	signal
229	Frequent Bowel Movements	170	4.1	4.1	signal
230	Anxiety	1,802	4.1	4.2	signal
231	Hepatic Pain	27	4.1	4.1	signal
232	Peripheral Coldness	87	4.1	4.1	signal
233	Alcohol Abuse	17	4.1	4.1	signal
234	Acne Cystic	19	4.0	4.0	signal
235	Anorgasmia	17	4.0	4.0	signal
236	Prescription Drug Used Without A Prescription	38	4.0	4.0	signal
237	Nightmare	215	4.0	4.0	signal
238	Self Esteem Decreased	15	3.9	3.9	signal
239	Tubulointerstitial Nephritis	115	3.9	4.0	signal
240	Drug Prescribing Error	119	3.9	3.9	signal
241	Paranasal Sinus Discomfort	23	3.9	3.9	signal
242	Frustration	22	3.9	3.9	signal
243	Lyme Disease	20	3.9	3.9	signal
244	Depression	1,376	3.9	4.0	signal
245	Stress	432	3.9	3.9	signal
246	Muscle Twitching	138	3.8	3.8	signal
247	Anxiety Disorder	20	3.8	3.8	signal
248	Therapy Change	56	3.7	3.7	signal
249	Endometriosis	27	3.6	3.6	signal
250	Feeling Abnormal	1,357	3.6	3.7	signal
251	Alcohol Use	21	3.6	3.6	signal
252	Product Packaging Quantity Issue	61	3.6	3.6	signal
253	Decreased Interest	33	3.6	3.6	signal
254	Suspected Counterfeit Product	22	3.6	3.6	signal
255	Insomnia	1,488	3.6	3.7	signal
256	Product Taste Abnormal	75	3.6	3.6	signal
257	Therapeutic Product Effect Decreased	244	3.5	3.5	signal
258	Sexual Dysfunction	64	3.5	3.5	signal
259	Migraine	514	3.5	3.5	signal
260	Eosinophilic Oesophagitis	14	3.5	3.5	signal
261	Hormone Level Abnormal	26	3.5	3.5	signal
262	Coeliac Disease	53	3.5	3.5	signal
263	Product Supply Issue	38	3.5	3.5	signal
264	Palpitations	629	3.4	3.5	signal
265	Drug Screen False Positive	15	3.4	3.4	signal
266	Unevaluable Event	405	3.4	3.5	signal
267	Alcoholism	23	3.4	3.4	signal
268	Mental Disorder	232	3.4	3.4	signal
269	Somnolence	1,065	3.4	3.5	signal
270	Substance Abuse	43	3.4	3.4	signal
271	Sluggishness	53	3.3	3.4	signal
272	Aphthous Ulcer	40	3.3	3.3	signal
273	Heart Rate Increased	514	3.3	3.4	signal
274	Food Allergy	39	3.3	3.3	signal
275	Psychiatric Symptom	38	3.3	3.3	signal
276	Muscle Tightness	83	3.3	3.3	signal
277	Product Label Issue	34	3.3	3.3	signal
278	Dry Mouth	408	3.2	3.3	signal
279	Sleep Terror	21	3.2	3.2	signal
280	Tongue Discomfort	21	3.2	3.2	signal
281	Brain Injury	50	3.2	3.2	signal
282	Poor Quality Sleep	106	3.2	3.2	signal
283	Hypersomnia	141	3.2	3.2	signal
284	Accidental Overdose	180	3.2	3.2	signal
285	Skin Abrasion	23	3.2	3.2	signal
286	Hallucination, Visual	103	3.1	3.2	signal
287	Formication	34	3.1	3.1	signal
288	Sleep Disorder	341	3.1	3.1	signal
289	Anal Fissure	26	3.1	3.1	signal
290	Autonomic Nervous System Imbalance	14	3.1	3.1	signal
291	Fear	131	3.1	3.1	signal
292	Malabsorption	25	3.1	3.1	signal
293	Infusion Site Pruritus	15	3.1	3.1	signal
294	Serotonin Syndrome	92	3.1	3.1	signal
295	Product Colour Issue	24	3.0	3.0	signal
296	Restlessness	172	3.0	3.0	signal
297	Middle Insomnia	87	3.0	3.0	signal
298	Heavy Menstrual Bleeding	37	3.0	3.0	signal
299	Akathisia	63	3.0	3.0	signal
300	Eating Disorder	98	2.9	2.9	signal
301	Inappropriate Schedule Of Product Administration	797	2.9	2.9	signal
302	Heart Rate Abnormal	25	2.9	2.9	signal
303	Nervousness	236	2.9	2.9	signal
304	Vitamin B12 Deficiency	18	2.9	2.9	signal
305	Disability	88	2.9	2.9	signal
306	Vitamin D Decreased	38	2.8	2.8	signal
307	Therapeutic Product Effect Delayed	20	2.8	2.8	signal
308	Tongue Ulceration	15	2.8	2.8	signal
309	Product Physical Consistency Issue	24	2.8	2.8	signal
310	Intentional Dose Omission	120	2.8	2.8	signal
311	Pharyngeal Swelling	42	2.8	2.8	signal
312	Anal Incontinence	39	2.8	2.8	signal
313	Intentional Product Use Issue	384	2.8	2.8	signal
314	Delusion	67	2.8	2.8	signal
315	Colitis Ulcerative	192	2.8	2.8	signal
316	Overweight	23	2.7	2.8	signal
317	Pharyngitis Streptococcal	46	2.7	2.7	signal
318	Impaired Gastric Emptying	54	2.7	2.7	signal
319	Drooling	29	2.7	2.7	signal
320	Poor Peripheral Circulation	18	2.7	2.7	signal
321	Tinnitus	190	2.6	2.7	signal
322	Panic Disorder	16	2.6	2.6	signal
323	Tongue Disorder	30	2.6	2.6	signal
324	Tension	25	2.6	2.6	signal
325	Decreased Appetite	947	2.6	2.7	signal
326	Dyskinesia	164	2.6	2.6	signal
327	Polydipsia	16	2.6	2.6	signal
328	Defaecation Urgency	28	2.6	2.6	signal
329	Jaw Disorder	22	2.6	2.6	signal
330	Eczema	200	2.5	2.6	signal
331	Food Poisoning	21	2.5	2.5	signal
332	Feeling Of Body Temperature Change	23	2.5	2.5	signal
333	Mental Impairment	95	2.5	2.5	signal
334	Hallucination	293	2.5	2.5	signal
335	Nonspecific Reaction	21	2.5	2.5	signal
336	Autoimmune Disorder	37	2.5	2.5	signal
337	Weight Fluctuation	40	2.5	2.5	signal
338	Hepatic Enzyme Abnormal	19	2.4	2.4	signal
339	Skin Odour Abnormal	15	2.4	2.4	signal
340	Eye Movement Disorder	26	2.4	2.4	signal
341	Metabolic Disorder	22	2.4	2.4	signal
342	Haematochezia	208	2.4	2.4	signal
343	Seasonal Allergy	53	2.4	2.4	signal
344	Caesarean Section	44	2.4	2.4	signal
345	Autoimmune Thyroiditis	14	2.4	2.4	signal
346	Product Prescribing Error	88	2.4	2.4	signal
347	Transfusion	39	2.4	2.4	signal
348	Hyperhidrosis	478	2.4	2.4	signal
349	Suicide Attempt	223	2.4	2.4	signal
350	Blood Pressure Diastolic Increased	17	2.3	2.3	signal
351	Hyperventilation	21	2.3	2.3	signal
352	Product Solubility Abnormal	18	2.3	2.3	signal
353	Road Traffic Accident	150	2.3	2.3	signal
354	Product Temperature Excursion Issue	17	2.3	2.3	signal
355	Glucose Tolerance Impaired	21	2.3	2.3	signal
356	Urine Abnormality	16	2.3	2.3	signal
357	Adverse Drug Reaction	319	2.3	2.3	signal
358	Dysgeusia	266	2.3	2.3	signal
359	Libido Decreased	44	2.3	2.3	signal
360	Drug Ineffective	4,670	2.3	2.5	signal
361	Accidental Exposure To Product By Child	24	2.3	2.3	signal
362	Condition Aggravated	1,054	2.2	2.3	signal
363	Tension Headache	15	2.2	2.2	signal
364	Mouth Swelling	20	2.2	2.2	signal
365	Systemic Lupus Erythematosus	123	2.2	2.2	signal
366	Incorrect Dosage Administered	17	2.2	2.2	signal
367	Weight Decreased	965	2.2	2.3	signal
368	Ear Infection	91	2.2	2.2	signal
369	Premature Baby	103	2.2	2.2	signal
370	Incoherent	22	2.2	2.2	signal
371	Blood Prolactin Increased	16	2.2	2.2	signal
372	Nocturia	41	2.2	2.2	signal
373	Blepharospasm	21	2.2	2.2	signal
374	Anal Fistula	18	2.2	2.2	signal
375	Thirst	60	2.2	2.2	signal
376	Vertigo	205	2.2	2.2	signal
377	Rebound Effect	38	2.1	2.1	signal
378	Therapy Interrupted	231	2.1	2.2	signal
379	Dysphoria	17	2.1	2.1	signal
380	Lethargy	190	2.1	2.1	signal
381	Menstrual Disorder	27	2.1	2.1	signal
382	Ear Pain	64	2.1	2.1	signal
383	Retching	70	2.1	2.1	signal
384	Wrong Technique In Product Usage Process	663	2.1	2.1	signal
385	Tachycardia	291	2.1	2.1	signal
386	Cerebral Disorder	24	2.1	2.1	signal
387	Mucous Stools	16	2.1	2.1	signal
388	Rectal Haemorrhage	140	2.1	2.1	signal
389	Sensory Disturbance	52	2.1	2.1	signal
390	Sensation Of Foreign Body	27	2.1	2.1	signal
391	Gastroenteritis Viral	58	2.1	2.1	signal
392	Hypophagia	81	2.0	2.0	signal
393	Pathogen Resistance	29	2.0	2.0	signal
394	Impaired Driving Ability	36	2.0	2.0	signal
395	Bowel Movement Irregularity	24	2.0	2.0	signal
396	Skin Laceration	34	2.0	2.0	signal
397	Erectile Dysfunction	81	2.0	2.0	signal
398	Hereditary Angioedema	33	2.0	2.0	signal
399	Drug Withdrawal Syndrome Neonatal	47	2.0	2.0	signal
400	Skin Infection	35	2.0	2.0	signal
401	Medication Error	174	2.0	2.0	signal
402	Viral Upper Respiratory Tract Infection	15	2.0	2.0	signal
403	Quality Of Life Decreased	42	2.0	2.0	signal
404	Poisoning Deliberate	29	2.0	2.0	no signal
405	Cold Sweat	55	2.0	2.0	no signal
406	Illness	310	2.0	2.0	no signal
407	Peripheral Vascular Disorder	16	2.0	2.0	no signal
408	Surgery	176	1.9	1.9	no signal
409	Arthritis	239	1.9	1.9	no signal
410	Accident	36	1.9	1.9	no signal
411	Cognitive Disorder	140	1.9	1.9	no signal
412	Obesity	48	1.9	1.9	no signal
413	Wrong Technique In Drug Usage Process	110	1.9	1.9	no signal
414	Weight Increased	658	1.9	1.9	no signal
415	Head Discomfort	52	1.9	1.9	no signal
416	Memory Impairment	405	1.9	1.9	no signal
417	Amenorrhoea	49	1.9	1.9	no signal
418	Product Distribution Issue	26	1.9	1.9	no signal
419	Drug Level Decreased	30	1.9	1.9	no signal
420	Neuralgia	71	1.9	1.9	no signal
421	Therapeutic Response Decreased	176	1.9	1.9	no signal
422	Appendicitis	27	1.9	1.9	no signal
423	Product Odour Abnormal	30	1.8	1.8	no signal
424	Sinus Disorder	57	1.8	1.8	no signal
425	Hypertensive Crisis	32	1.8	1.8	no signal
426	Blood Pressure Increased	439	1.8	1.8	no signal
427	Headache	1,765	1.8	1.8	no signal
428	Tremor	468	1.8	1.8	no signal
429	Apnoea	22	1.8	1.8	no signal
430	Dental Caries	31	1.8	1.8	no signal
431	Dermatitis Atopic	140	1.8	1.8	no signal
432	Economic Problem	43	1.8	1.8	no signal
433	Hysterectomy	24	1.8	1.8	no signal
434	Respiration Abnormal	19	1.8	1.8	no signal
435	Vitamin D Deficiency	27	1.8	1.8	no signal
436	Acne	211	1.8	1.8	no signal
437	Stress Cardiomyopathy	16	1.8	1.8	no signal
438	Ankylosing Spondylitis	36	1.8	1.8	no signal
439	Confusional State	447	1.8	1.8	no signal
440	Infusion Site Swelling	17	1.8	1.8	no signal
441	Hypoaesthesia	413	1.8	1.8	no signal
442	Hair Growth Abnormal	19	1.8	1.8	no signal
443	Deafness Unilateral	15	1.7	1.7	no signal
444	Product Use Complaint	42	1.7	1.7	no signal
445	Decreased Activity	29	1.7	1.7	no signal
446	Streptococcal Infection	15	1.7	1.7	no signal
447	Abdominal Discomfort	449	1.7	1.7	no signal
448	Photophobia	50	1.7	1.7	no signal
449	Multiple Allergies	21	1.7	1.7	no signal
450	Ocular Discomfort	29	1.7	1.7	no signal
451	Proctalgia	17	1.7	1.7	no signal
452	Fibromyalgia	64	1.7	1.7	no signal
453	Fatigue	2,044	1.7	1.7	no signal
454	Abdominal Pain Upper	539	1.7	1.7	no signal
455	Irritable Bowel Syndrome	56	1.7	1.7	no signal
456	Dystonia	51	1.7	1.7	no signal
457	Nerve Compression	24	1.7	1.7	no signal
458	Tardive Dyskinesia	74	1.7	1.7	no signal
459	Meniscus Injury	16	1.7	1.7	no signal
460	Activities Of Daily Living Impaired	52	1.7	1.7	no signal
461	Feeling Hot	158	1.6	1.7	no signal
462	Product Dose Omission In Error	69	1.6	1.6	no signal
463	Mouth Ulceration	54	1.6	1.6	no signal
464	Sars-cov-2 Test Positive	34	1.6	1.6	no signal
465	Incorrect Dose Administered	572	1.6	1.6	no signal
466	Speech Disorder	133	1.6	1.6	no signal
467	Ligament Sprain	25	1.6	1.6	no signal
468	Oral Herpes	49	1.6	1.6	no signal
469	Scratch	26	1.6	1.6	no signal
470	Infusion Site Pain	32	1.6	1.6	no signal
471	Menstruation Delayed	26	1.6	1.6	no signal
472	Oral Mucosal Blistering	16	1.6	1.6	no signal
473	Muscle Spasticity	31	1.6	1.6	no signal
474	Product Dose Omission Issue	711	1.6	1.6	no signal
475	Product Administered To Patient Of Inappropriate Age	15	1.6	1.6	no signal
476	Type 1 Diabetes Mellitus	15	1.6	1.6	no signal
477	Visual Field Defect	18	1.6	1.6	no signal
478	Angiopathy	14	1.6	1.6	no signal
479	Sinusitis	254	1.6	1.6	no signal
480	Heart Rate Irregular	56	1.6	1.6	no signal
481	Device Information Output Issue	18	1.6	1.6	no signal
482	Pallor	67	1.6	1.6	no signal
483	Lip Dry	22	1.6	1.6	no signal
484	Maternal Exposure During Pregnancy	216	1.6	1.6	no signal
485	Dysmenorrhoea	32	1.6	1.6	no signal
486	Adverse Event	225	1.6	1.6	no signal
487	Blood Pressure Abnormal	48	1.5	1.6	no signal
488	Coordination Abnormal	34	1.5	1.5	no signal
489	Bladder Disorder	24	1.5	1.5	no signal
490	Pharyngitis	30	1.5	1.5	no signal
491	Covid-19	425	1.5	1.5	no signal
492	Vision Blurred	328	1.5	1.5	no signal
493	Micturition Urgency	27	1.5	1.5	no signal
494	Drug Dose Omission	398	1.5	1.5	no signal
495	Foreign Body In Reproductive Tract	21	1.5	1.5	no signal
496	Product Prescribing Issue	48	1.5	1.5	no signal
497	Carpal Tunnel Syndrome	33	1.5	1.5	no signal
498	Ear Discomfort	24	1.5	1.5	no signal
499	Off Label Use	2,030	1.5	1.5	no signal
500	Incorrect Route Of Product Administration	39	1.5	1.5	no signal
501	Upper-airway Cough Syndrome	19	1.5	1.5	no signal
502	Lymphocyte Count Decreased	41	1.5	1.5	no signal
503	Blood Testosterone Decreased	16	1.5	1.5	no signal
504	Galactorrhoea	15	1.5	1.5	no signal
505	Arthropod Bite	17	1.5	1.5	no signal
506	Discomfort	140	1.5	1.5	no signal
507	Ventricular Extrasystoles	24	1.5	1.5	no signal
508	Paraesthesia	363	1.5	1.5	no signal
509	Intervertebral Disc Protrusion	50	1.5	1.5	no signal
510	Presyncope	55	1.5	1.5	no signal
511	Respiratory Rate Increased	20	1.4	1.4	no signal
512	Aphasia	68	1.4	1.4	no signal
513	Oropharyngeal Pain	207	1.4	1.4	no signal
514	Neck Pain	125	1.4	1.4	no signal
515	Poor Venous Access	23	1.4	1.4	no signal
516	Pregnancy	45	1.4	1.4	no signal
517	Bedridden	29	1.4	1.4	no signal
518	Nephrolithiasis	101	1.4	1.4	no signal
519	Dermatitis Contact	25	1.4	1.4	no signal
520	Haemorrhoids	43	1.4	1.4	no signal
521	Uterine Leiomyoma	16	1.4	1.4	no signal
522	Hyperaesthesia	18	1.4	1.4	no signal
523	Eosinophil Count Increased	18	1.4	1.4	no signal
524	Oral Discomfort	30	1.4	1.4	no signal
525	Nerve Injury	24	1.4	1.4	no signal
526	Intervertebral Disc Degeneration	20	1.4	1.4	no signal
527	Neutrophil Count Increased	22	1.4	1.4	no signal
528	Gynaecomastia	67	1.4	1.4	no signal
529	Generalised Tonic-clonic Seizure	35	1.4	1.4	no signal
530	Seizure	245	1.4	1.4	no signal
531	Drug Dispensing Error	33	1.4	1.4	no signal
532	Ankle Fracture	33	1.4	1.4	no signal
533	Disorientation	84	1.4	1.4	no signal
534	Dysgraphia	14	1.4	1.4	no signal
535	Skin Discolouration	97	1.3	1.4	no signal
536	Exposure During Pregnancy	131	1.3	1.3	no signal
537	Viral Infection	70	1.3	1.3	no signal
538	Foot Fracture	40	1.3	1.3	no signal
539	Device Mechanical Issue	27	1.3	1.3	no signal
540	Ovarian Cyst	21	1.3	1.3	no signal
541	Tooth Fracture	23	1.3	1.3	no signal
542	Pain In Jaw	59	1.3	1.3	no signal
543	Gastrointestinal Disorder	183	1.3	1.3	no signal
544	Malnutrition	23	1.3	1.3	no signal
545	Drug Intolerance	199	1.3	1.3	no signal
546	Dizziness	1,027	1.3	1.3	no signal
547	Hypoaesthesia Oral	31	1.3	1.3	no signal
548	Intentional Underdose	15	1.3	1.3	no signal
549	Schizophrenia	25	1.3	1.3	no signal
550	Abnormal Dreams	57	1.3	1.3	no signal
551	Feeling Cold	57	1.3	1.3	no signal
552	Nicotine Dependence	16	1.3	1.3	no signal
553	Dermatitis	42	1.3	1.3	no signal
554	Feeding Disorder	40	1.3	1.3	no signal
555	Treatment Noncompliance	109	1.3	1.3	no signal
556	Lymphadenopathy	71	1.3	1.3	no signal
557	Anhedonia	53	1.3	1.3	no signal
558	Loss Of Consciousness	256	1.3	1.3	no signal
559	Urinary Incontinence	59	1.3	1.3	no signal
560	Intentional Product Misuse	173	1.3	1.3	no signal
561	Chest Discomfort	203	1.3	1.3	no signal
562	Gastroenteritis	29	1.3	1.3	no signal
563	Amnesia	130	1.3	1.3	no signal
564	Breast Tenderness	15	1.3	1.3	no signal
565	Hypothyroidism	63	1.3	1.3	no signal
566	Product Dispensing Error	43	1.3	1.3	no signal
567	Deep Vein Thrombosis	129	1.3	1.3	no signal
568	Nausea	1,555	1.3	1.3	no signal
569	Limb Discomfort	61	1.3	1.3	no signal
570	Respiratory Tract Infection	51	1.3	1.3	no signal
571	Back Disorder	32	1.3	1.3	no signal
572	Hidradenitis	17	1.3	1.3	no signal
573	Blood Iron Decreased	23	1.2	1.2	no signal
574	Blood Thyroid Stimulating Hormone Increased	18	1.2	1.2	no signal
575	Exposure Via Skin Contact	44	1.2	1.2	no signal
576	Complication Of Device Removal	33	1.2	1.2	no signal
577	Hyperthyroidism	28	1.2	1.2	no signal
578	Infusion Site Erythema	16	1.2	1.2	no signal
579	Muscle Spasms	354	1.2	1.2	no signal
580	Night Sweats	62	1.2	1.2	no signal
581	Menstruation Irregular	51	1.2	1.2	no signal
582	Movement Disorder	62	1.2	1.2	no signal
583	Therapy Cessation	98	1.2	1.2	no signal
584	Skin Fissures	36	1.2	1.2	no signal
585	Electrocardiogram Abnormal	15	1.2	1.2	no signal
586	Spinal Operation	23	1.2	1.2	no signal
587	Drug Interaction	300	1.2	1.2	no signal
588	Complication Of Device Insertion	35	1.2	1.2	no signal
589	Diplopia	49	1.2	1.2	no signal
590	Facial Paralysis	16	1.2	1.2	no signal
591	Abscess	30	1.2	1.2	no signal
592	Chest Pain	349	1.2	1.2	no signal
593	Dizziness Postural	18	1.2	1.2	no signal
594	Scar	32	1.2	1.2	no signal
595	Drug Abuse	156	1.2	1.2	no signal
596	Optic Neuritis	17	1.2	1.2	no signal
597	Fistula	21	1.2	1.2	no signal
598	Syncope	186	1.2	1.2	no signal
599	Therapeutic Product Effect Incomplete	131	1.2	1.2	no signal
600	Muscle Strain	16	1.2	1.2	no signal
601	Pollakiuria	77	1.2	1.2	no signal
602	Cholecystectomy	21	1.2	1.2	no signal
603	Skin Reaction	26	1.2	1.2	no signal
604	Back Injury	20	1.2	1.2	no signal
605	Wrist Fracture	22	1.2	1.2	no signal
606	Embedded Device	18	1.2	1.2	no signal
607	Gastrointestinal Pain	20	1.2	1.2	no signal
608	Oral Pain	41	1.2	1.2	no signal
609	Swelling Face	118	1.2	1.2	no signal
610	Heart Rate Decreased	64	1.2	1.2	no signal
611	Paralysis	26	1.2	1.2	no signal
612	Body Temperature Increased	37	1.2	1.2	no signal
613	Head Injury	57	1.2	1.2	no signal
614	Product Administration Error	36	1.2	1.2	no signal
615	Urinary Retention	60	1.2	1.2	no signal
616	Product Dose Omission	119	1.1	1.1	no signal
617	Sleep Disorder Due To A General Medical Condition	29	1.1	1.1	no signal
618	Intentional Drug Misuse	38	1.1	1.1	no signal
619	Hypertension	378	1.1	1.1	no signal
620	Device Breakage	70	1.1	1.1	no signal
621	Liver Injury	43	1.1	1.1	no signal
622	Supraventricular Tachycardia	17	1.1	1.1	no signal
623	Asthma	199	1.1	1.1	no signal
624	Treatment Failure	145	1.1	1.1	no signal
625	Skin Swelling	15	1.1	1.1	no signal
626	Gastrooesophageal Reflux Disease	141	1.1	1.1	no signal
627	Choking	34	1.1	1.1	no signal
628	Knee Operation	17	1.1	1.1	no signal
629	Taste Disorder	35	1.1	1.1	no signal
630	Musculoskeletal Stiffness	153	1.1	1.1	no signal
631	Visual Impairment	214	1.1	1.1	no signal
632	Dysuria	64	1.1	1.1	no signal
633	Eructation	33	1.1	1.1	no signal
634	Dry Eye	84	1.1	1.1	no signal
635	Gastric Ulcer	33	1.1	1.1	no signal
636	Nasopharyngitis	320	1.1	1.1	no signal
637	Psoriatic Arthropathy	69	1.1	1.1	no signal
638	Extrapyramidal Disorder	43	1.1	1.1	no signal
639	Drug Withdrawal Syndrome	152	1.1	1.1	no signal
640	Cyanosis	27	1.1	1.1	no signal
641	Foot Deformity	19	1.1	1.1	no signal
642	Hot Flush	129	1.1	1.1	no signal
643	Sciatica	27	1.1	1.1	no signal
644	Photosensitivity Reaction	28	1.1	1.1	no signal
645	Sneezing	38	1.1	1.1	no signal
646	Product Use In Unapproved Indication	415	1.1	1.1	no signal
647	Bronchitis	126	1.1	1.1	no signal
648	Kidney Infection	33	1.1	1.1	no signal
649	Loss Of Libido	15	1.1	1.1	no signal
650	Vaginal Haemorrhage	71	1.1	1.1	no signal
651	Procedural Pain	46	1.1	1.1	no signal
652	Limb Injury	45	1.1	1.1	no signal
653	Toothache	30	1.1	1.1	no signal
654	Vomiting	774	1.1	1.1	no signal
655	Overdose	357	1.1	1.1	no signal
656	Eye Pain	91	1.1	1.1	no signal
657	Blood Pressure Decreased	109	1.1	1.1	no signal
658	Sinus Tachycardia	23	1.0	1.0	no signal
659	Urticaria	270	1.0	1.0	no signal
660	Dysarthria	61	1.0	1.0	no signal
661	Arrhythmia	77	1.0	1.0	no signal
662	Malaise	710	1.0	1.0	no signal
663	Fluid Retention	82	1.0	1.0	no signal
664	Grand Mal Convulsion	15	1.0	1.0	no signal
665	Emotional Distress	194	1.0	1.0	no signal
666	Pelvic Pain	29	1.0	1.0	no signal
667	Status Epilepticus	18	1.0	1.0	no signal
668	Sputum Discoloured	15	1.0	1.0	no signal
669	Poisoning	20	1.0	1.0	no signal
670	Upper Respiratory Tract Infection	73	1.0	1.0	no signal
671	Motor Dysfunction	16	1.0	1.0	no signal
672	Hypersensitivity	293	1.0	1.0	no signal
673	Spinal Disorder	15	1.0	1.0	no signal
674	Extra Dose Administered	63	1.0	1.0	no signal
675	Abdominal Pain Lower	40	1.0	1.0	no signal
676	Incorrect Product Administration Duration	32	1.0	1.0	no signal
677	Contusion	151	1.0	1.0	no signal
678	Musculoskeletal Discomfort	27	1.0	1.0	no signal
679	Facial Pain	14	1.0	1.0	no signal
680	Temperature Intolerance	16	1.0	1.0	no signal
681	Lip Swelling	52	1.0	1.0	no signal
682	Nasal Congestion	91	1.0	1.0	no signal
683	Uveitis	21	1.0	1.0	no signal
684	Tachypnoea	21	1.0	1.0	no signal
685	Pain In Extremity	457	1.0	1.0	no signal
686	Orthostatic Hypotension	27	1.0	1.0	no signal
687	Joint Injury	33	1.0	1.0	no signal
688	Vitreous Floaters	15	1.0	1.0	no signal
689	Dyspepsia	151	1.0	1.0	no signal
690	Platelet Count Increased	20	1.0	1.0	no signal
691	Skin Haemorrhage	22	1.0	1.0	no signal
692	Conjunctivitis	28	1.0	1.0	no signal
693	Retinal Detachment	14	1.0	1.0	no signal
694	Throat Tightness	41	1.0	1.0	no signal
695	Rash	658	1.0	1.0	no signal
696	Gallbladder Disorder	27	1.0	1.0	no signal
697	Muscle Rigidity	18	1.0	1.0	no signal
698	Alopecia	296	1.0	1.0	no signal
699	Influenza	168	1.0	1.0	no signal
700	Abdominal Pain	349	1.0	1.0	no signal
701	Blood Cholesterol Increased	70	1.0	1.0	no signal
702	Scab	17	1.0	1.0	no signal
703	Vaginal Discharge	15	1.0	1.0	no signal
704	Localised Infection	36	1.0	1.0	no signal
705	Pain	914	0.9	0.9	no signal
706	Glossodynia	33	0.9	0.9	no signal
707	Pharyngeal Oedema	23	0.9	0.9	no signal
708	Dysphagia	139	0.9	0.9	no signal
709	Pulmonary Embolism	140	0.9	0.9	no signal
710	Abortion Spontaneous	59	0.9	0.9	no signal
711	Foetal Exposure During Pregnancy	119	0.9	0.9	no signal
712	Eye Disorder	48	0.9	0.9	no signal
713	Paraesthesia Oral	21	0.9	0.9	no signal
714	Oral Candidiasis	19	0.9	0.9	no signal
715	Hepatic Steatosis	27	0.9	0.9	no signal
716	Drug Dependence	235	0.9	0.9	no signal
717	Ulcer	23	0.9	0.9	no signal
718	Tooth Infection	19	0.9	0.9	no signal
719	Complication Associated With Device	19	0.9	0.9	no signal
720	Multiple Sclerosis	69	0.9	0.9	no signal
721	Convulsion	82	0.9	0.9	no signal
722	Myocarditis	16	0.9	0.9	no signal
723	Asthenia	530	0.9	0.9	no signal
724	Epilepsy	43	0.9	0.9	no signal
725	Breast Pain	15	0.9	0.9	no signal
726	Sinus Congestion	19	0.9	0.9	no signal
727	Salivary Hypersecretion	14	0.9	0.9	no signal
728	Glaucoma	27	0.9	0.9	no signal
729	Burning Sensation	98	0.9	0.9	no signal
730	Constipation	302	0.9	0.9	no signal
731	Electrocardiogram Qt Prolonged	50	0.9	0.9	no signal
732	Drug Effect Incomplete	51	0.9	0.9	no signal
733	Anaphylactic Reaction	76	0.9	0.9	no signal
734	Disease Recurrence	66	0.9	0.9	no signal
735	Myalgia	235	0.9	0.9	no signal
736	Skin Disorder	46	0.9	0.9	no signal
737	Rhinorrhoea	89	0.9	0.9	no signal
738	Dry Throat	14	0.9	0.9	no signal
739	Rash Macular	48	0.9	0.9	no signal
740	Oesophagitis	15	0.9	0.9	no signal
741	Jaundice	37	0.9	0.9	no signal
742	Eye Discharge	14	0.9	0.9	no signal
743	Tooth Abscess	14	0.9	0.9	no signal
744	Blood Urine Present	26	0.9	0.9	no signal
745	Thyroid Disorder	21	0.9	0.9	no signal
746	Immunodeficiency	20	0.9	0.9	no signal
747	Back Pain	315	0.9	0.9	no signal
748	Eye Swelling	50	0.9	0.9	no signal
749	Upper Limb Fracture	27	0.9	0.9	no signal
750	Abdominal Distension	140	0.9	0.9	no signal
751	Hepatic Enzyme Increased	91	0.9	0.9	no signal
752	Pyrexia	462	0.9	0.9	no signal
753	Blood Pressure Fluctuation	32	0.8	0.8	no signal
754	Blood Potassium Decreased	40	0.8	0.8	no signal
755	Candida Infection	22	0.8	0.8	no signal
756	Muscular Weakness	149	0.8	0.8	no signal
757	Osteopenia	20	0.8	0.8	no signal
758	Lower Limb Fracture	25	0.8	0.8	no signal
759	Cellulitis	66	0.8	0.8	no signal
760	Menorrhagia	26	0.8	0.8	no signal
761	Infusion Related Reaction	85	0.8	0.8	no signal
762	Vasculitis	15	0.8	0.8	no signal
763	Skin Lesion	35	0.8	0.8	no signal
764	Diarrhoea Haemorrhagic	12	0.8	0.8	no signal
765	Spinal Pain	15	0.8	0.8	no signal
766	Dehydration	170	0.8	0.8	no signal
767	Balance Disorder	110	0.8	0.8	no signal
768	Fungal Infection	42	0.8	0.8	no signal
769	Dysphonia	73	0.8	0.8	no signal
770	Flushing	127	0.8	0.8	no signal
771	Arthralgia	515	0.8	0.8	no signal
772	Eye Irritation	69	0.8	0.8	no signal
773	Hiatus Hernia	16	0.8	0.8	no signal
774	Influenza Like Illness	101	0.8	0.8	no signal
775	Joint Stiffness	32	0.8	0.8	no signal
776	Aphonia	17	0.8	0.8	no signal
777	Chills	143	0.8	0.8	no signal
778	Metrorrhagia	21	0.8	0.8	no signal
779	Cyst	15	0.8	0.8	no signal
780	Adverse Reaction	16	0.8	0.8	no signal
781	Abnormal Weight Gain	15	0.8	0.8	no signal
782	Aspiration	13	0.8	0.8	no signal
783	Throat Irritation	53	0.8	0.8	no signal
784	Product Packaging Issue	11	0.8	0.8	no signal
785	Erythema	243	0.8	0.8	no signal
786	Skin Exfoliation	98	0.8	0.8	no signal
787	Gastritis	31	0.8	0.8	no signal
788	Gastric Disorder	41	0.8	0.8	no signal
789	Epistaxis	88	0.8	0.7	no signal
790	Adrenal Insufficiency	14	0.7	0.7	no signal
791	Abortion Induced	11	0.7	0.7	no signal
792	Cough	326	0.7	0.7	no signal
793	Injection Site Discomfort	12	0.7	0.7	no signal
794	Product Preparation Error	24	0.7	0.7	no signal
795	Cholelithiasis	38	0.7	0.7	no signal
796	Injection Site Induration	15	0.7	0.7	no signal
797	Chromaturia	26	0.7	0.7	no signal
798	Fall	382	0.7	0.7	no signal
799	Swelling	107	0.7	0.7	no signal
800	Hernia	22	0.7	0.7	no signal
801	Joint Dislocation	12	0.7	0.7	no signal
802	Angioedema	50	0.7	0.7	no signal
803	Drug Hypersensitivity	219	0.7	0.7	no signal
804	Incorrect Product Storage	15	0.7	0.7	no signal
805	Tooth Extraction	14	0.7	0.7	no signal
806	Peripheral Swelling	172	0.7	0.7	no signal
807	Tooth Disorder	25	0.7	0.7	no signal
808	Nervous System Disorder	35	0.7	0.7	no signal
809	Staphylococcal Infection	37	0.7	0.7	no signal
810	Dyspnoea	630	0.7	0.7	no signal
811	Gout	20	0.7	0.7	no signal
812	Pain Of Skin	30	0.7	0.7	no signal
813	Brain Oedema	14	0.7	0.7	no signal
814	Clostridium Difficile Infection	24	0.7	0.7	no signal
815	Blindness	45	0.7	0.7	no signal
816	Laryngitis	12	0.7	0.7	no signal
817	Device Use Issue	19	0.7	0.7	no signal
818	Musculoskeletal Chest Pain	17	0.7	0.7	no signal
819	Pruritus	414	0.7	0.7	no signal
820	Tendonitis	17	0.7	0.7	no signal
821	Iron Deficiency Anaemia	10	0.7	0.7	no signal
822	Rotator Cuff Syndrome	14	0.7	0.7	no signal
823	Ill-defined Disorder	66	0.7	0.7	no signal
824	Skin Burning Sensation	77	0.7	0.7	no signal
825	Product Complaint	27	0.7	0.7	no signal
826	Injury	76	0.7	0.7	no signal
827	Device Expulsion	70	0.7	0.7	no signal
828	Nodule	14	0.7	0.7	no signal
829	Wheezing	63	0.7	0.7	no signal
830	Folliculitis	11	0.7	0.7	no signal
831	Underdose	76	0.7	0.7	no signal
832	Incontinence	11	0.7	0.7	no signal
833	Muscle Atrophy	13	0.7	0.7	no signal
834	Stevens-johnson Syndrome	23	0.7	0.7	no signal
835	Product Storage Error	89	0.7	0.7	no signal
836	Injection Site Irritation	13	0.7	0.7	no signal
837	Ocular Hyperaemia	48	0.7	0.7	no signal
838	Expired Product Administered	34	0.7	0.7	no signal
839	Blood Pressure Systolic Increased	20	0.7	0.7	no signal
840	Cerebrovascular Accident	173	0.6	0.6	no signal
841	Productive Cough	48	0.6	0.6	no signal
842	Cardiomyopathy	15	0.6	0.6	no signal
843	Unresponsive To Stimuli	26	0.6	0.6	no signal
844	Knee Arthroplasty	21	0.6	0.6	no signal
845	Eye Pruritus	33	0.6	0.6	no signal
846	Blister	56	0.6	0.6	no signal
847	Gait Inability	33	0.6	0.6	no signal
848	Injection Site Urticaria	24	0.6	0.6	no signal
849	Dry Skin	130	0.6	0.6	no signal
850	Immune System Disorder	13	0.6	0.6	no signal
851	Drug Ineffective For Unapproved Indication	55	0.6	0.6	no signal
852	Hypothermia	10	0.6	0.6	no signal
853	Tendon Rupture	12	0.6	0.6	no signal
854	Arthropathy	54	0.6	0.6	no signal
855	Cardiomegaly	12	0.6	0.6	no signal
856	Hypokinesia	14	0.6	0.6	no signal
857	Flank Pain	9	0.6	0.6	no signal
858	Ageusia	24	0.6	0.6	no signal
859	Blood Triglycerides Increased	17	0.6	0.6	no signal
860	Hospitalisation	146	0.6	0.6	no signal
861	Tenderness	10	0.6	0.6	no signal
862	General Physical Health Deterioration	110	0.6	0.6	no signal
863	Psoriasis	125	0.6	0.6	no signal
864	Eye Inflammation	9	0.6	0.6	no signal
865	Haematocrit Decreased	19	0.6	0.6	no signal
866	Incorrect Dose Administered By Device	24	0.6	0.6	no signal
867	Eyelid Oedema	11	0.6	0.6	no signal
868	Depressed Level Of Consciousness	37	0.6	0.6	no signal
869	Lacrimation Increased	28	0.6	0.6	no signal
870	Injection Site Swelling	71	0.6	0.6	no signal
871	Angina Pectoris	27	0.6	0.6	no signal
872	Rash Papular	21	0.6	0.6	no signal
873	Colitis	35	0.6	0.6	no signal
874	Contraindicated Product Administered	28	0.6	0.6	no signal
875	Musculoskeletal Pain	49	0.6	0.6	no signal
876	Completed Suicide	78	0.6	0.6	no signal
877	Rib Fracture	19	0.6	0.6	no signal
878	Covid-19 Pneumonia	11	0.6	0.6	no signal
879	Diarrhoea	594	0.6	0.6	no signal
880	Blindness Unilateral	13	0.6	0.6	no signal
881	Ataxia	11	0.6	0.6	no signal
882	Myoclonus	11	0.6	0.6	no signal
883	Infection	133	0.6	0.6	no signal
884	Therapy Non-responder	41	0.6	0.6	no signal
885	Hyperlipidaemia	11	0.6	0.6	no signal
886	Inflammation	47	0.6	0.6	no signal
887	Joint Swelling	110	0.6	0.6	no signal
888	Bursitis	11	0.6	0.6	no signal
889	Stomatitis	55	0.6	0.6	no signal
890	Body Temperature Decreased	9	0.6	0.6	no signal
891	Blood Sodium Decreased	17	0.6	0.6	no signal
892	Injection Site Reaction	62	0.6	0.6	no signal
893	Hepatitis C	11	0.6	0.6	no signal
894	Ventricular Fibrillation	10	0.6	0.6	no signal
895	Osteoarthritis	38	0.6	0.6	no signal
896	Urinary Tract Infection	151	0.6	0.6	no signal
897	Dysstasia	26	0.6	0.6	no signal
898	Herpes Zoster	51	0.6	0.6	no signal
899	Respiratory Tract Congestion	14	0.6	0.6	no signal
900	Rash Generalised	23	0.6	0.6	no signal
901	Gait Disturbance	167	0.6	0.6	no signal
902	Increased Tendency To Bruise	8	0.6	0.6	no signal
903	Central Nervous System Lesion	12	0.6	0.6	no signal
904	Injection Site Pain	263	0.6	0.5	no signal
905	Haematemesis	22	0.6	0.6	no signal
906	Petechiae	9	0.6	0.6	no signal
907	Device Defective	14	0.6	0.6	no signal
908	Toxicity To Various Agents	145	0.6	0.5	no signal
909	Mental Status Changes	24	0.6	0.6	no signal
910	Wound	24	0.6	0.6	no signal
911	Therapy Partial Responder	13	0.6	0.6	no signal
912	Injection Site Rash	26	0.5	0.5	no signal
913	Drug Effective For Unapproved Indication	25	0.5	0.5	no signal
914	Madarosis	10	0.5	0.5	no signal
915	Injection Site Bruising	67	0.5	0.5	no signal
916	Flatulence	48	0.5	0.5	no signal
917	Drug Level Increased	14	0.5	0.5	no signal
918	Cystitis	27	0.5	0.5	no signal
919	Rhabdomyolysis	35	0.5	0.5	no signal
920	Needle Issue	24	0.5	0.5	no signal
921	Laceration	8	0.5	0.5	no signal
922	Drug Administration Error	26	0.5	0.5	no signal
923	Altered State Of Consciousness	18	0.5	0.5	no signal
924	Device Deployment Issue	10	0.5	0.5	no signal
925	Multiple Sclerosis Relapse	57	0.5	0.5	no signal
926	Mobility Decreased	59	0.5	0.5	no signal
927	Eye Haemorrhage	11	0.5	0.5	no signal
928	Cardiovascular Disorder	21	0.5	0.5	no signal
929	Blood Creatine Phosphokinase Increased	24	0.5	0.5	no signal
930	Encephalopathy	20	0.5	0.5	no signal
931	Injection Site Mass	30	0.5	0.5	no signal
932	Device Issue	71	0.5	0.5	no signal
933	Red Blood Cell Sedimentation Rate Increased	9	0.5	0.5	no signal
934	Rash Erythematous	38	0.5	0.5	no signal
935	Blood Glucose Abnormal	15	0.5	0.5	no signal
936	Diabetes Mellitus	62	0.5	0.5	no signal
937	Drug Dose Omission By Device	62	0.5	0.5	no signal
938	No Therapeutic Response	10	0.5	0.5	no signal
939	Rheumatoid Arthritis	91	0.5	0.5	no signal
940	Application Site Irritation	10	0.5	0.5	no signal
941	Eye Infection	9	0.5	0.5	no signal
942	Application Site Rash	11	0.5	0.5	no signal
943	Rash Pruritic	43	0.5	0.5	no signal
944	Eyelid Ptosis	8	0.5	0.5	no signal
945	Haemorrhage	82	0.5	0.5	no signal
946	Musculoskeletal Disorder	15	0.5	0.5	no signal
947	Alanine Aminotransferase Increased	48	0.5	0.5	no signal
948	Skin Ulcer	20	0.5	0.5	no signal
949	Intestinal Obstruction	29	0.5	0.5	no signal
950	Deafness	20	0.5	0.5	no signal
951	Pancreatitis Acute	17	0.5	0.5	no signal
952	Brain Neoplasm	7	0.5	0.5	no signal
953	Diverticulitis	21	0.5	0.5	no signal
954	Abasia	19	0.5	0.5	no signal
955	Neuroleptic Malignant Syndrome	9	0.5	0.5	no signal
956	Bacterial Infection	14	0.5	0.5	no signal
957	Clostridium Difficile Colitis	8	0.5	0.5	no signal
958	White Blood Cell Count Increased	29	0.5	0.5	no signal
959	Bone Pain	44	0.5	0.5	no signal
960	Liver Function Test Increased	16	0.5	0.5	no signal
961	Skin Irritation	34	0.5	0.5	no signal
962	Pulmonary Mass	11	0.5	0.5	no signal
963	Device Dislocation	32	0.5	0.5	no signal
964	Wound Infection	8	0.5	0.5	no signal
965	Acute Hepatic Failure	10	0.5	0.5	no signal
966	Impaired Healing	24	0.5	0.5	no signal
967	Accidental Exposure To Product	73	0.5	0.5	no signal
968	Secretion Discharge	9	0.5	0.5	no signal
969	Post Procedural Complication	14	0.5	0.5	no signal
970	Blood Glucose Decreased	35	0.5	0.5	no signal
971	Hip Arthroplasty	11	0.5	0.5	no signal
972	Tooth Loss	15	0.5	0.5	no signal
973	Decreased Immune Responsiveness	7	0.5	0.5	no signal
974	Circumstance Or Information Capable Of Leading To Medication Error	24	0.5	0.5	no signal
975	Neuropathy Peripheral	67	0.5	0.5	no signal
976	Injection Site Pruritus	47	0.5	0.5	no signal
977	Hepatitis	18	0.4	0.4	no signal
978	Circulatory Collapse	12	0.4	0.4	no signal
979	Pancreatitis	37	0.4	0.4	no signal
980	Hypotension	140	0.4	0.4	no signal
981	Hypotonia	7	0.4	0.4	no signal
982	Haematoma	18	0.4	0.4	no signal
983	Faeces Discoloured	15	0.4	0.4	no signal
984	Anosmia	10	0.4	0.4	no signal
985	Device Leakage	29	0.4	0.4	no signal
986	Pruritus Generalised	15	0.4	0.4	no signal
987	Application Site Pain	15	0.4	0.4	no signal
988	Injection Site Warmth	14	0.4	0.4	no signal
989	Cataract	40	0.4	0.4	no signal
990	Hair Texture Abnormal	9	0.4	0.4	no signal
991	Blood Bilirubin Increased	18	0.4	0.4	no signal
992	Renal Pain	7	0.4	0.4	no signal
993	Thyroid Cancer	8	0.4	0.4	no signal
994	Glomerular Filtration Rate Decreased	8	0.4	0.4	no signal
995	Hypokalaemia	30	0.4	0.4	no signal
996	Generalised Oedema	8	0.4	0.4	no signal
997	Face Oedema	11	0.4	0.4	no signal
998	Device Occlusion	9	0.4	0.4	no signal
999	Pneumonia	208	0.4	0.4	no signal
1000	Proteinuria	12	0.4	0.4	no signal
1001	Hair Colour Changes	8	0.4	0.4	no signal
1002	Glycosylated Haemoglobin Increased	16	0.4	0.4	no signal
1003	C-reactive Protein Increased	23	0.4	0.4	no signal
1004	Gamma-glutamyltransferase Increased	14	0.4	0.4	no signal
1005	Oedema Peripheral	77	0.4	0.4	no signal
1006	Cardiac Arrest	52	0.4	0.4	no signal
1007	Local Swelling	11	0.4	0.4	no signal
1008	Type 2 Diabetes Mellitus	21	0.4	0.4	no signal
1009	Transient Ischaemic Attack	21	0.4	0.4	no signal
1010	Drug-induced Liver Injury	19	0.4	0.4	no signal
1011	Osteomyelitis	11	0.4	0.4	no signal
1012	Product Administered At Inappropriate Site	11	0.4	0.4	no signal
1013	Ventricular Tachycardia	10	0.4	0.4	no signal
1014	Prescribed Underdose	12	0.4	0.4	no signal
1015	Visual Acuity Reduced	20	0.4	0.4	no signal
1016	Oedema	32	0.4	0.4	no signal
1017	Hemiparesis	10	0.4	0.4	no signal
1018	Gingival Bleeding	8	0.4	0.4	no signal
1019	Bradycardia	31	0.4	0.4	no signal
1020	Thrombosis	47	0.4	0.4	no signal
1021	Injection Site Haemorrhage	46	0.4	0.4	no signal
1022	Hypoglycaemia	28	0.4	0.4	no signal
1023	Cardiac Disorder	54	0.4	0.4	no signal
1024	Mass	8	0.4	0.4	no signal
1025	Respiratory Depression	7	0.4	0.4	no signal
1026	Small Intestinal Obstruction	7	0.4	0.4	no signal
1027	Application Site Erythema	15	0.4	0.4	no signal
1028	Product Adhesion Issue	20	0.4	0.4	no signal
1029	Chronic Kidney Disease	43	0.4	0.4	no signal
1030	Cardiogenic Shock	8	0.4	0.4	no signal
1031	Injection Site Erythema	69	0.4	0.4	no signal
1032	Hypoacusis	24	0.4	0.4	no signal
1033	Renal Disorder	26	0.4	0.4	no signal
1034	Body Height Decreased	6	0.4	0.4	no signal
1035	Lower Respiratory Tract Infection	25	0.4	0.4	no signal
1036	Delirium	19	0.4	0.4	no signal
1037	Wrong Technique In Device Usage Process	25	0.3	0.3	no signal
1038	Anaphylactic Shock	14	0.3	0.3	no signal
1039	Injection Site Nodule	6	0.3	0.3	no signal
1040	Aspartate Aminotransferase Increased	29	0.3	0.3	no signal
1041	Tuberculosis	7	0.3	0.3	no signal
1042	Liver Disorder	24	0.3	0.3	no signal
1043	Respiratory Arrest	15	0.3	0.3	no signal
1044	Obstructive Airways Disorder	6	0.3	0.3	no signal
1045	Osteoporosis	22	0.3	0.3	no signal
1046	Nephropathy	5	0.3	0.3	no signal
1047	Joint Range Of Motion Decreased	7	0.3	0.3	no signal
1048	Post Procedural Haemorrhage	6	0.3	0.3	no signal
1049	Syringe Issue	9	0.3	0.3	no signal
1050	Liver Function Test Abnormal	15	0.3	0.3	no signal
1051	Basal Cell Carcinoma	8	0.3	0.3	no signal
1052	Laboratory Test Abnormal	15	0.3	0.3	no signal
1053	Dyspnoea Exertional	19	0.3	0.3	no signal
1054	Macular Degeneration	6	0.3	0.3	no signal
1055	Diabetic Ketoacidosis	12	0.3	0.3	no signal
1056	Pneumocystis Jirovecii Pneumonia	5	0.3	0.3	no signal
1057	Respiratory Disorder	15	0.3	0.3	no signal
1058	Lymphopenia	7	0.3	0.3	no signal
1059	Incorrect Drug Administration Duration	14	0.3	0.3	no signal
1060	Dependence	27	0.3	0.3	no signal
1061	Hypoxia	17	0.3	0.3	no signal
1062	Full Blood Count Abnormal	5	0.3	0.3	no signal
1063	Upper Gastrointestinal Haemorrhage	8	0.3	0.3	no signal
1064	Sudden Death	5	0.3	0.3	no signal
1065	Intraocular Pressure Increased	6	0.3	0.3	no signal
1066	Bone Loss	7	0.3	0.3	no signal
1067	Leukopenia	23	0.3	0.3	no signal
1068	Device Delivery System Issue	12	0.3	0.3	no signal
1069	Spinal Fracture	9	0.3	0.3	no signal
1070	Device Malfunction	30	0.3	0.3	no signal
1071	Lung Infection	7	0.3	0.3	no signal
1072	Myocardial Ischaemia	5	0.3	0.3	no signal
1073	White Blood Cell Count Decreased	47	0.3	0.3	no signal
1074	Ovarian Cancer	4	0.3	0.3	no signal
1075	Deformity	4	0.3	0.3	no signal
1076	Squamous Cell Carcinoma	4	0.3	0.3	no signal
1077	Multiple Fractures	7	0.3	0.3	no signal
1078	Cerebral Haemorrhage	15	0.3	0.3	no signal
1079	Pulmonary Arterial Hypertension	6	0.3	0.3	no signal
1080	Meningioma	6	0.3	0.3	no signal
1081	Inflammatory Bowel Disease	4	0.3	0.3	no signal
1082	Injection Site Discolouration	5	0.3	0.3	no signal
1083	Device Failure	6	0.3	0.3	no signal
1084	Oxygen Saturation Decreased	22	0.3	0.3	no signal
1085	Helicobacter Infection	4	0.3	0.3	no signal
1086	Drug Reaction With Eosinophilia And Systemic Symptoms	10	0.2	0.2	no signal
1087	Unintended Pregnancy	4	0.2	0.2	no signal
1088	Blood Creatinine Increased	25	0.2	0.2	no signal
1089	Bone Density Decreased	12	0.2	0.2	no signal
1090	Drug Administered At Inappropriate Site	4	0.2	0.2	no signal
1091	Lactic Acidosis	12	0.2	0.2	no signal
1092	Lung Disorder	18	0.2	0.2	no signal
1093	Osteonecrosis	12	0.2	0.2	no signal
1094	Anaemia	69	0.2	0.2	no signal
1095	Coronary Artery Disease	11	0.2	0.2	no signal
1096	Dementia	10	0.2	0.2	no signal
1097	Pulmonary Oedema	16	0.2	0.2	no signal
1098	Application Site Pruritus	8	0.2	0.2	no signal
1099	Renal Failure	47	0.2	0.2	no signal
1100	Internal Haemorrhage	4	0.2	0.2	no signal
1101	Atrial Fibrillation	34	0.2	0.2	no signal
1102	Febrile Neutropenia	23	0.2	0.2	no signal
1103	Neoplasm	4	0.2	0.2	no signal
1104	Renal Impairment	29	0.2	0.2	no signal
1105	Chronic Obstructive Pulmonary Disease	18	0.2	0.2	no signal
1106	Unintentional Medical Device Removal	4	0.2	0.2	no signal
1107	Ischaemic Stroke	6	0.2	0.2	no signal
1108	Coma	16	0.2	0.2	no signal
1109	Colon Cancer	5	0.2	0.2	no signal
1110	Sepsis	37	0.2	0.2	no signal
1111	Myocardial Infarction	58	0.2	0.2	no signal
1112	Lymphoma	5	0.2	0.2	no signal
1113	Injection Site Extravasation	4	0.2	0.2	no signal
1114	Breast Cancer	30	0.2	0.2	no signal
1115	Leukaemia	3	0.2	0.2	no signal
1116	Acute Kidney Injury	48	0.2	0.2	no signal
1117	Neoplasm Malignant	21	0.2	0.2	no signal
1118	Blood Glucose Increased	59	0.2	0.2	no signal
1119	Genital Haemorrhage	4	0.2	0.2	no signal
1120	Malignant Melanoma	4	0.2	0.2	no signal
1121	Coronary Artery Occlusion	4	0.2	0.2	no signal
1122	Skeletal Injury	3	0.2	0.2	no signal
1123	Diabetes Mellitus Inadequate Control	5	0.2	0.2	no signal
1124	Skin Cancer	6	0.2	0.2	no signal
1125	Blood Glucose Fluctuation	3	0.2	0.2	no signal
1126	Hyponatraemia	15	0.2	0.2	no signal
1127	Cardiac Failure	21	0.2	0.2	no signal
1128	Respiratory Failure	19	0.2	0.2	no signal
1129	Blood Count Abnormal	4	0.2	0.2	no signal
1130	Incorrect Route Of Drug Administration	9	0.2	0.2	no signal
1131	Haemoglobin Decreased	25	0.2	0.2	no signal
1132	Device Use Error	8	0.1	0.1	no signal
1133	Prostatic Specific Antigen Increased	3	0.1	0.1	no signal
1134	Neutropenia	29	0.1	0.1	no signal
1135	Device Difficult To Use	14	0.1	0.1	no signal
1136	Injection Site Haematoma	3	0.1	0.1	no signal
1137	Drug Exposure During Pregnancy	7	0.1	0.1	no signal
1138	Device Adhesion Issue	3	0.1	0.1	no signal
1139	Lung Neoplasm Malignant	8	0.1	0.1	no signal
1140	Pharmaceutical Product Complaint	5	0.1	0.1	no signal
1141	Breast Cancer Female	5	0.1	0.1	no signal
1142	Platelet Count Decreased	19	0.1	0.1	no signal
1143	Disease Progression	20	0.1	0.1	no signal
1144	Gastrointestinal Haemorrhage	14	0.1	0.1	no signal
1145	Injury Associated With Device	3	0.1	0.1	no signal
1146	Thrombocytopenia	16	0.1	0.1	no signal
1147	Death	103	0.1	0.1	no signal