Reaction

Drug Effect Variable reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,133 reports · 23 co-occurring drugs

As of the last recalculation, Drug Effect Variable appears in 1,133 FAERS reports alongside 23 co-occurring drug terms. The strongest observed disproportionality signal is ACETAMINOPHEN, ASPIRIN (NSAID) AND CAFFEINE (PRR 73.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Acetaminophen, Aspirin (Nsaid) And Caffeine6473.273.5
Acetaminophen, Aspirin, And Caffeine6459.159.2
Carbidopa And Levodopa12855.755.9
Lisdexamfetamine Dimesylate7242.742.8
Rasagiline Mesylate1830.230.2
Amantadine1720.520.5
Pramipexole1518.218.2
Rotigotine1316.716.7
Suvorexant1014.314.3
Guanfacine614.114.1
Amphetamine613.413.4
Polyethylene Glycol 400913.113.1
Instalax Polyethylene Glycol 3350811.911.9
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate2611.811.8
Oxybutynin1811.511.5
Levodopa710.710.7
Linaclotide149.79.8
Romiplostim78.68.6
Asenapine Maleate48.58.5
Cariprazine35.95.9
Glycerin, Lidocaine45.35.3
Docosanol45.05.0
Dalfampridine184.74.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.