Reaction

Tic reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,391 reports · 84 co-occurring drugs

As of the last recalculation, Tic appears in 5,391 FAERS reports alongside 84 co-occurring drug terms. The strongest observed disproportionality signal is ATOMOXETINE HYDROCHLORIDE (PRR 67.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Atomoxetine Hydrochloride	386	67.4	68.5
Guanfacine	112	56.1	56.9
Lisdexamfetamine Dimesylate	360	45.1	45.5
Methylphenidate Hydrochloride	492	35.2	35.5
Methylphenidate	194	26.8	27.0
Lurasidone Hydrochloride	75	14.0	14.1
Ziprasidone	56	12.4	12.4
Aripiprazole	361	12.1	12.2
Risperidone	384	11.9	12.0
Montelukast	245	11.8	11.8
Ziprasidone Mesylate	41	11.2	11.2
Valbenazine	68	10.6	10.6
Aripiprazole Oral	103	9.8	9.8
Aripiprazole Orally Disintegrating	103	9.8	9.8
Montelukast Sodium	279	9.3	9.3
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	93	8.8	8.8
Brexpiprazole	35	8.2	8.2
Haloperidol	50	8.0	8.0
Amphetamine	17	8.0	8.0
Cariprazine	19	7.9	7.9
Haloperidol Lactate	50	7.9	7.9
Fluoxetine	124	7.3	7.3
Sertraline	209	7.1	7.1
Clonidine	92	7.0	7.0
Polyethylene Glycol 3350	169	7.0	7.0
Fluoxetine Hydrochloride	206	6.4	6.5
Modafinil	49	5.9	5.9
Melatonin	82	5.9	5.9
Oxcarbazepine	49	5.9	5.9
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	52	5.7	5.7
Paliperidone	34	5.7	5.7
Lamotrigine	180	5.4	5.4
Elexacaftor, Tezacaftor, And Ivacaftor	17	5.3	5.3
Lamotirigine	96	5.2	5.3
Lamotrigine Extended-Release	96	5.2	5.3
Lamotrigine Chewable Dispersible	96	5.2	5.3
Lithium Carbonate	22	5.0	5.0
Asenapine Maleate	11	4.9	4.9
Sertraline Hydrochloride	143	4.8	4.8
Brivaracetam	11	4.7	4.7
Quetiapine	228	4.7	4.7
Olanzapine Pamoate	49	4.7	4.7
Lithium	30	4.6	4.6
Lithium Bromatum	30	4.6	4.6
Valproate Sodium	24	4.5	4.5
Salmeterol Xinafoate	10	4.5	4.5
Divalproex Sodium	52	4.3	4.4
Amantadine	17	4.3	4.3
Olanzapine	111	4.1	4.1
Desloratadine	11	4.0	4.0
Fexofenadine Hcl	9	3.8	3.8
Instalax Polyethylene Glycol 3350	12	3.7	3.7
Polyethylene Glycol 400	12	3.7	3.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	8	3.6	3.6
Armodafinil	19	3.5	3.5
Quetiapine Fumarate	25	3.3	3.3
Bupropion Hydrochloride	81	3.2	3.2
Carbamazepine	55	3.2	3.2
Ropinirole	12	3.0	3.0
Vilazodone Hydrochloride	7	2.9	2.9
Cetiirizine	32	2.9	2.9
Cetirizine Hydrochloride	120	2.9	2.9
Naltrexone Hydrochloride And Bupropion Hydrochloride	6	2.7	2.7
Topiramate	62	2.6	2.6
Fexofenadine	11	2.6	2.6
Lacosamide	24	2.5	2.5
Zonisamide	9	2.4	2.4
Bupropion	27	2.3	2.3
Paliperidone Palmitate	18	2.2	2.2
Multivitamin	27	2.1	2.1
Vortioxetine	9	2.0	2.0
Ivacaftor	4	1.9	1.9
Desvenlafaxine Succinate	13	1.9	1.9
Cenobamate	4	1.9	1.9
Sodium Oxybate	28	1.6	1.6
Clozapine	49	1.5	1.5
Somatropin	26	1.4	1.4
Vigabatrin	5	1.3	1.3
Cannabidiol	8	1.3	1.3
Medroxyprogesterone Acetate	17	1.3	1.3
Rimegepant Sulfate	4	1.2	1.2
Dornase Alfa	6	1.2	1.2
Esketamine Hydrochloride	3	0.6	0.6
Pimavanserin Tartrate	9	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.