Reaction

Creatinine Renal Clearance Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 742 reports · 42 co-occurring drugs

As of the last recalculation, Creatinine Renal Clearance Increased appears in 742 FAERS reports alongside 42 co-occurring drug terms. The strongest observed disproportionality signal is QUINAPRIL HYDROCHLORIDE (PRR 219.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Quinapril Hydrochloride	57	219.5	221.1
Quinine	44	152.9	153.7
Diltiazem Hydrochloride Extended-Release Tablets	53	140.6	141.3
Atropine	37	131.8	132.4
Magnesium Hydroxide	54	121.1	121.6
Bisacodyl Suppositories	50	116.2	116.6
Biscodyl	50	115.1	115.5
Bisacodyl	50	106.8	107.2
Atropine Sulfate	38	103.9	104.3
Cyclobenzaprine Hydrochloride	28	90.8	91.1
Oxazepam	60	85.1	85.3
Acetaminophen And Codeine	30	71.9	72.1
Amitriptyline Hydrochloride	40	67.5	67.7
Zinc	50	60.9	61.0
Zinc Chloride	50	60.5	60.6
Phenobarbital	29	58.4	58.5
Zinc Gluconate	50	57.4	57.6
Diltiazem Hydrochloride	55	48.1	48.2
Lactulose	59	46.8	46.9
Oxcarbazepine	50	46.2	46.3
Docusate Sodium 100Mg	37	45.6	45.7
Telmisartan	24	38.9	39.0
Rosuvastatin Calcium	37	38.7	38.8
Nitroglycerin	64	36.5	36.6
Cyclobenzaprine	58	35.3	35.3
Levofloxacin	65	33.0	33.1
Levofloxacin In 5% Dextrose	65	33.0	33.1
Sennosides	33	32.4	32.4
Psyllium Husk	11	31.7	31.7
Antacid	49	30.9	30.9
Carbamazepine	55	24.8	24.8
Canagliflozin	23	22.2	22.2
Bosutinib	5	15.7	15.7
Remdesivir	7	14.9	14.9
Oxymorphone Hydrochloride	6	14.5	14.5
Morphine Sulfate	57	14.2	14.2
Alpelisib	4	12.9	12.9
Entecavir	5	12.1	12.1
Dofetilide	4	10.7	10.7
Abemaciclib	7	9.9	9.9
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	3	8.4	8.4
Daratumumab	11	7.8	7.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.