Reaction

Frustration reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,586 reports · 38 co-occurring drugs

As of the last recalculation, Frustration appears in 3,586 FAERS reports alongside 38 co-occurring drug terms. The strongest observed disproportionality signal is INTERFERON BETA-1A (PRR 19.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Interferon Beta-1A	553	19.5	19.5
Varenicline Tartrate	207	15.9	15.9
Natalizumab	401	14.3	14.3
Orlistat	54	12.3	12.3
Teriparatide	199	10.8	10.8
Atomoxetine Hydrochloride	34	8.4	8.4
Nitrofurantoin	17	6.0	6.0
Nitrofurantoin (Monohydrate/Macrocrystals)	17	5.9	5.9
Insulin Lispro	130	5.6	5.6
Desvenlafaxine Succinate	22	4.8	4.8
Dimethyl Fumarate	95	4.6	4.6
Insulin Human	31	4.6	4.6
Simvastatin	182	4.4	4.4
Ziprasidone Mesylate	10	4.1	4.1
Lisdexamfetamine Dimesylate	22	3.9	3.9
Methylphenidate Hydrochloride	38	3.8	3.8
Human Insulin	8	3.7	3.7
Lisinopril And Hydrochlorothiazide Tablets	5	3.7	3.7
Raloxifene Hydrochloride	9	3.6	3.6
Peginterferon Alfa-2A	33	3.6	3.6
Donepezil Hydrochloride	21	3.3	3.3
Ziprasidone	10	3.3	3.3
Guanfacine	4	3.0	3.0
Armodafinil	10	2.8	2.8
Interferon Beta-1B	9	2.7	2.7
Asenapine Maleate	4	2.7	2.7
Fesoterodine Fumarate	5	2.7	2.7
Teriflunomide	18	2.3	2.3
Fingolimod Hcl	33	2.2	2.2
Insulin Glargine	93	2.2	2.2
Dalfampridine	26	2.1	2.1
Drospirenone And Ethinyl Estradiol	16	2.1	2.1
Ribavirin	22	2.0	2.0
Lurasidone Hydrochloride	7	1.9	1.9
Sofosbuvir	6	1.8	1.8
Glatiramer Acetate	17	1.7	1.7
Pseudoephedrine Hcl	3	1.6	1.6
Levonorgestrel	28	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.