OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Guanfacine

1,001 flagged reaction(s) · 26,777 total co-reports · max PRR 705.1
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Gaming Disorder 4 705.1 705.5 signal
2 Poor School Attendance 4 528.8 529.1 signal
3 Disruptive Mood Dysregulation Disorder 7 276.3 276.5 signal
4 Macular Detachment 18 217.3 217.8 signal
5 Selective Mutism 6 203.4 203.5 signal
6 Intermittent Explosive Disorder 8 194.1 194.3 signal
7 Anticholinergic Effect 4 173.4 173.5 signal
8 Oppositional Defiant Disorder 23 163.9 164.4 signal
9 Electrocardiogram T Wave Amplitude Increased 4 118.8 118.9 signal
10 Forced Expiratory Volume Abnormal 6 115.0 115.0 signal
11 Withdrawal Hypertension 8 110.7 110.9 signal
12 Foetal Alcohol Syndrome 4 110.2 110.2 signal
13 Defiant Behaviour 12 110.2 110.3 signal
14 Restless Leg Augmentation Syndrome 5 100.9 101.0 signal
15 Atrioventricular Dissociation 7 90.3 90.4 signal
16 Self-destructive Behaviour 22 81.1 81.4 signal
17 Choroidal Effusion 22 75.8 76.1 signal
18 Negativism 19 68.5 68.7 signal
19 Disturbance In Social Behaviour 59 68.5 69.0 signal
20 Fractional Exhaled Nitric Oxide Increased 4 63.3 63.4 signal
21 Educational Problem 37 60.4 60.7 signal
22 Grandiosity 8 60.3 60.3 signal
23 Hypertensive Urgency 11 58.5 58.6 signal
24 Impulsive Behaviour 77 56.1 56.7 signal
25 Tic 112 56.1 56.9 signal
26 Body Mass Index Decreased 9 54.1 54.1 signal
27 Conduct Disorder 4 52.1 52.1 signal
28 Zinc Deficiency 4 51.1 51.1 signal
29 Drug-genetic Interaction 6 49.9 49.9 signal
30 Electrocardiogram T Wave Peaked 7 47.8 47.9 signal
31 Activation Syndrome 6 46.8 46.8 signal
32 Blood Prolactin Decreased 3 46.4 46.4 signal
33 Trichotillomania 10 46.2 46.3 signal
34 Electrocardiogram Qt Shortened 5 45.4 45.5 signal
35 Oromandibular Dystonia 12 45.3 45.4 signal
36 Nephrogenic Diabetes Insipidus 19 45.0 45.1 signal
37 Distractibility 17 40.1 40.2 signal
38 Growth Failure 5 39.2 39.3 signal
39 Orthostatic Intolerance 10 38.1 38.1 signal
40 Drug Dose Titration Not Performed 24 37.9 38.0 signal
41 Serous Retinal Detachment 11 37.6 37.6 signal
42 Change In Sustained Attention 4 36.6 36.6 signal
43 Cardiovascular Symptom 5 35.6 35.7 signal
44 Sinus Arrhythmia 17 35.4 35.5 signal
45 Anion Gap 8 33.9 33.9 signal
46 Incorrect Product Dosage Form Administered 5 33.7 33.7 signal
47 Dermatillomania 7 32.5 32.6 signal
48 Brugada Syndrome 12 31.8 31.8 signal
49 Electrocardiogram St-t Segment Abnormal 5 30.5 30.5 signal
50 Periodic Limb Movement Disorder 4 29.4 29.4 signal
51 Choroidal Detachment 6 29.3 29.3 signal
52 Bradypnoea 28 28.2 28.3 signal
53 Behaviour Disorder 54 27.5 27.7 signal
54 Manufacturing Materials Issue 4 27.1 27.1 signal
55 Attention Deficit/hyperactivity Disorder 32 26.5 26.6 signal
56 Sinus Arrest 15 26.2 26.3 signal
57 Autism Spectrum Disorder 53 26.2 26.4 signal
58 Attention Deficit Hyperactivity Disorder 40 26.1 26.2 signal
59 Enuresis 37 24.8 24.9 signal
60 Distributive Shock 20 24.5 24.5 signal
61 Grimacing 7 24.3 24.3 signal
62 Upper Airway Obstruction 8 24.3 24.3 signal
63 Excessive Eye Blinking 13 23.8 23.8 signal
64 Head Banging 5 23.5 23.5 signal
65 Patient Uncooperative 4 23.2 23.3 signal
66 Subretinal Fluid 9 23.0 23.1 signal
67 Psychomotor Hyperactivity 141 22.9 23.3 signal
68 Wolff-parkinson-white Syndrome 4 22.8 22.9 signal
69 Postural Orthostatic Tachycardia Syndrome 11 22.7 22.7 signal
70 Hypertensive Encephalopathy 5 22.6 22.6 signal
71 Adhesive Tape Use 3 22.0 22.0 signal
72 Verbal Abuse 4 21.9 21.9 signal
73 Autism 8 21.0 21.0 signal
74 Aggression 388 20.9 21.9 signal
75 Electrocardiogram T Wave Abnormal 12 20.9 20.9 signal
76 Hypertensive Emergency 9 20.8 20.8 signal
77 Posturing 4 20.8 20.8 signal
78 Social Anxiety Disorder 5 20.5 20.5 signal
79 Anticholinergic Syndrome 12 20.3 20.4 signal
80 Starvation 6 20.2 20.2 signal
81 Stereotypy 7 20.2 20.2 signal
82 Sinus Bradycardia 72 20.1 20.2 signal
83 Homicidal Ideation 29 19.2 19.3 signal
84 Protrusion Tongue 4 18.7 18.7 signal
85 Vasoplegia Syndrome 11 18.4 18.4 signal
86 Allergy To Plants 3 17.7 17.8 signal
87 Electrocardiogram Qt Prolonged 232 17.4 17.9 signal
88 Change In Seizure Presentation 4 16.4 16.4 signal
89 Hallucination, Tactile 4 16.3 16.4 signal
90 Pharyngeal Paraesthesia 9 15.5 15.6 signal
91 Physical Assault 12 15.5 15.5 signal
92 Abnormal Behaviour 225 15.2 15.6 signal
93 Self-injurious Ideation 23 14.8 14.9 signal
94 Selective Eating Disorder 5 14.8 14.8 signal
95 Hostility 14 14.7 14.7 signal
96 Intrusive Thoughts 6 14.3 14.3 signal
97 Drug Effect Variable 6 14.1 14.1 signal
98 Sedation Complication 13 14.0 14.0 signal
99 Bradycardia 271 13.7 14.2 signal
100 Drug Administered To Patient Of Inappropriate Age 37 13.7 13.8 signal
101 Transcription Medication Error 8 13.7 13.7 signal
102 Cardiac Aneurysm 5 13.6 13.6 signal
103 Drug Effect Increased 16 13.4 13.5 signal
104 Staring 12 13.4 13.4 signal
105 Priapism 17 13.2 13.2 signal
106 Logorrhoea 17 13.0 13.0 signal
107 Judgement Impaired 7 12.9 12.9 signal
108 Blood Urea Nitrogen/creatinine Ratio Increased 3 12.6 12.6 signal
109 Intentional Self-injury 94 12.5 12.7 signal
110 Anger 153 12.1 12.3 signal
111 Cystic Fibrosis Respiratory Infection Suppression 4 12.0 12.0 signal
112 Hyperammonaemia 22 11.9 11.9 signal
113 Inhibitory Drug Interaction 7 11.8 11.9 signal
114 Abulia 4 11.8 11.8 signal
115 Growth Retardation 13 11.8 11.8 signal
116 Screaming 28 11.8 11.8 signal
117 Hyporesponsive To Stimuli 5 11.7 11.7 signal
118 Accidental Exposure To Product By Child 29 11.4 11.5 signal
119 Intentional Overdose 264 11.1 11.5 signal
120 Blunted Affect 3 11.1 11.1 signal
121 Sleep Talking 7 11.0 11.0 signal
122 Affective Disorder 32 11.0 11.0 signal
123 Affect Lability 39 10.9 10.9 signal
124 Catatonia 21 10.8 10.9 signal
125 Product Administered To Patient Of Inappropriate Age 24 10.7 10.8 signal
126 Obsessive-compulsive Disorder 32 10.7 10.7 signal
127 Drug Tolerance 20 10.6 10.6 signal
128 Electrocardiogram Qrs Complex Prolonged 20 10.5 10.5 signal
129 Impulse-control Disorder 8 10.4 10.5 signal
130 Sedation 100 10.3 10.4 signal
131 Immune Thrombocytopenic Purpura 11 10.3 10.3 signal
132 Autonomic Nervous System Imbalance 11 10.3 10.3 signal
133 Mast Cell Activation Syndrome 5 10.2 10.2 signal
134 Atonic Seizures 3 10.1 10.1 signal
135 Disinhibition 6 10.0 10.0 signal
136 Atypical Haemolytic Uraemic Syndrome 3 10.0 10.0 signal
137 Bipolar I Disorder 8 9.8 9.8 signal
138 Product Administration Interrupted 28 9.8 9.8 signal
139 Dysphemia 16 9.8 9.8 signal
140 Sleep Terror 15 9.6 9.6 signal
141 Self Injurious Behaviour 11 9.6 9.6 signal
142 Eosinophilic Oesophagitis 9 9.4 9.4 signal
143 Weight Gain Poor 8 9.3 9.3 signal
144 Psychotic Symptom 7 9.2 9.2 signal
145 Dark Circles Under Eyes 5 9.1 9.1 signal
146 Sleep Deficit 7 9.1 9.1 signal
147 Suicidal Behaviour 14 9.0 9.0 signal
148 Antipsychotic Drug Level Above Therapeutic 3 9.0 9.0 signal
149 Forced Expiratory Volume Decreased 9 8.5 8.5 signal
150 Inappropriate Affect 5 8.4 8.4 signal
151 Stress Cardiomyopathy 18 8.4 8.4 signal
152 Bicytopenia 6 8.3 8.3 signal
153 Product Substitution Issue 175 8.2 8.3 signal
154 Hyperphagia 12 8.1 8.1 signal
155 Dizziness Postural 29 8.1 8.1 signal
156 Electrocardiogram St Segment Elevation 10 8.1 8.1 signal
157 Nephrogenic Anaemia 14 8.0 8.1 signal
158 Antisocial Behaviour 3 8.0 8.0 signal
159 Gaze Palsy 5 7.9 7.9 signal
160 Suicidal Ideation 269 7.9 8.1 signal
161 Carbon Dioxide Increased 4 7.9 7.9 signal
162 Infusion Site Discharge 5 7.9 7.9 signal
163 Long Qt Syndrome 7 7.8 7.8 signal
164 Social Problem 12 7.8 7.8 signal
165 Irritability 174 7.8 7.9 signal
166 Tachyphrenia 10 7.8 7.8 signal
167 Heart Rate Abnormal 16 7.7 7.8 signal
168 Dystonia 56 7.7 7.8 signal
169 Serotonin Syndrome 55 7.7 7.8 signal
170 Learning Disorder 7 7.7 7.7 signal
171 Frustration Tolerance Decreased 23 7.7 7.7 signal
172 Torticollis 6 7.7 7.7 signal
173 Allergy To Animal 3 7.7 7.7 signal
174 Tonic Convulsion 4 7.7 7.7 signal
175 Drooling 19 7.4 7.4 signal
176 Agitation 203 7.4 7.6 signal
177 Mania 45 7.4 7.4 signal
178 Infective Pulmonary Exacerbation Of Cystic Fibrosis 15 7.3 7.4 signal
179 Negative Thoughts 8 7.3 7.3 signal
180 Skin Striae 4 7.2 7.2 signal
181 Drug Prescribing Error 52 7.2 7.2 signal
182 Personality Disorder 7 7.1 7.1 signal
183 Flat Affect 6 7.1 7.1 signal
184 Infusion Site Pruritus 8 6.9 6.9 signal
185 Violence-related Symptom 4 6.9 6.9 signal
186 Blood Creatinine Decreased 8 6.9 6.9 signal
187 Increased Appetite 48 6.9 6.9 signal
188 Disturbance In Attention 138 6.9 7.0 signal
189 Initial Insomnia 26 6.8 6.9 signal
190 Wrong Dose 6 6.6 6.7 signal
191 Bipolar Disorder 27 6.6 6.6 signal
192 Orthostatic Hypotension 43 6.6 6.6 signal
193 Self Esteem Decreased 6 6.6 6.6 signal
194 Inability To Afford Medication 24 6.6 6.6 signal
195 Neuroleptic Malignant Syndrome 29 6.5 6.6 signal
196 Drug Level Above Therapeutic 11 6.5 6.5 signal
197 Emotional Disorder 75 6.5 6.5 signal
198 Pulseless Electrical Activity 10 6.4 6.4 signal
199 Contraindicated Product Prescribed 4 6.4 6.4 signal
200 Hallucination, Auditory 38 6.4 6.4 signal
201 Hallucinations, Mixed 10 6.4 6.4 signal
202 Somnolence 471 6.3 6.6 signal
203 Drug Titration Error 6 6.2 6.2 signal
204 Suspected Suicide 11 6.2 6.2 signal
205 Cerebral Disorder 17 6.2 6.2 signal
206 Gynaecomastia 72 6.2 6.2 signal
207 Therapeutic Product Ineffective 9 6.2 6.2 signal
208 Therapy Change 22 6.1 6.1 signal
209 Depressive Symptom 8 6.1 6.1 signal
210 Somnambulism 15 6.1 6.1 signal
211 Medication Residue Present 11 6.1 6.1 signal
212 Dissociation 17 6.1 6.1 signal
213 Pre-existing Condition Improved 14 6.0 6.0 signal
214 Posterior Reversible Encephalopathy Syndrome 21 5.9 5.9 signal
215 Bezoar 3 5.8 5.8 signal
216 Reaction To Excipient 5 5.8 5.8 signal
217 Hypomania 8 5.8 5.8 signal
218 Recalled Product Administered 19 5.8 5.8 signal
219 Hypertrichosis 4 5.8 5.8 signal
220 Wrong Technique In Drug Usage Process 79 5.8 5.8 signal
221 Product Availability Issue 48 5.7 5.8 signal
222 Listless 7 5.7 5.7 signal
223 Drug Delivery System Issue 4 5.7 5.7 signal
224 Narcolepsy 4 5.7 5.7 signal
225 Therapeutic Response Changed 13 5.6 5.6 signal
226 Anxiety Disorder 7 5.6 5.6 signal
227 Tearfulness 9 5.6 5.6 signal
228 Blood Pressure Decreased 138 5.6 5.7 signal
229 Conversion Disorder 4 5.6 5.6 signal
230 Lethargy 116 5.4 5.5 signal
231 Hyperprolactinaemia 13 5.4 5.4 signal
232 Sudden Hearing Loss 4 5.3 5.3 signal
233 Device Material Issue 4 5.3 5.3 signal
234 Hypothermia 20 5.3 5.3 signal
235 Prescribed Overdose 38 5.3 5.3 signal
236 Respiratory Depression 24 5.3 5.3 signal
237 Hallucination, Visual 41 5.2 5.3 signal
238 Mood Swings 62 5.2 5.3 signal
239 Suicide Attempt 118 5.2 5.3 signal
240 Post-traumatic Stress Disorder 13 5.2 5.2 signal
241 Mood Altered 52 5.1 5.2 signal
242 Blood Prolactin Increased 9 5.1 5.1 signal
243 Social Avoidant Behaviour 11 5.1 5.1 signal
244 Application Site Erythema 49 5.0 5.0 signal
245 Application Site Scab 4 4.9 4.9 signal
246 Atrioventricular Block First Degree 8 4.9 4.9 signal
247 Therapeutic Product Effect Variable 7 4.9 4.9 signal
248 Generalised Tonic-clonic Seizure 30 4.9 4.9 signal
249 Restlessness 67 4.9 4.9 signal
250 Substance-induced Psychotic Disorder 4 4.9 4.9 signal
251 Atrioventricular Block 14 4.8 4.9 signal
252 Drug Administered At Inappropriate Site 19 4.8 4.8 signal
253 Supraventricular Extrasystoles 6 4.8 4.8 signal
254 Abnormal Loss Of Weight 12 4.8 4.8 signal
255 Dysphoria 9 4.7 4.8 signal
256 Syncope 174 4.7 4.7 signal
257 Hypertonic Bladder 5 4.7 4.7 signal
258 Bundle Branch Block Right 8 4.7 4.7 signal
259 Infusion Site Reaction 5 4.6 4.6 signal
260 Product Preparation Issue 10 4.6 4.6 signal
261 Psychotic Disorder 50 4.5 4.6 signal
262 Appetite Disorder 11 4.5 4.5 signal
263 Withdrawal Syndrome 71 4.5 4.5 signal
264 Drug Administration Error 52 4.5 4.5 signal
265 Application Site Discomfort 3 4.5 4.5 signal
266 Blood Immunoglobulin E Increased 4 4.4 4.4 signal
267 Cardiac Dysfunction 6 4.4 4.4 signal
268 Rebound Acid Hypersecretion 5 4.4 4.4 signal
269 Device Mechanical Issue 21 4.4 4.4 signal
270 Altered State Of Consciousness 35 4.4 4.4 signal
271 Persecutory Delusion 4 4.4 4.4 signal
272 Middle Insomnia 30 4.3 4.3 signal
273 Incorrect Drug Administration Duration 46 4.3 4.3 signal
274 Akathisia 22 4.3 4.3 signal
275 Presyncope 39 4.3 4.3 signal
276 Application Site Irritation 20 4.3 4.3 signal
277 Hyperacusis 6 4.3 4.3 signal
278 Abnormal Weight Gain 20 4.3 4.3 signal
279 Therapy Partial Responder 24 4.3 4.3 signal
280 Snoring 6 4.3 4.3 signal
281 Respiratory Rate Decreased 5 4.3 4.3 signal
282 Electroencephalogram Abnormal 5 4.3 4.3 signal
283 Petit Mal Epilepsy 8 4.2 4.2 signal
284 Depressed Level Of Consciousness 62 4.2 4.2 signal
285 Trismus 8 4.2 4.2 signal
286 Product Quality Issue 208 4.1 4.2 signal
287 Infusion Site Haemorrhage 5 4.1 4.1 signal
288 Pallor 42 4.1 4.1 signal
289 Crying 56 4.1 4.1 signal
290 Respiratory Acidosis 6 4.1 4.1 signal
291 Immunosuppressant Drug Level Increased 5 4.1 4.1 signal
292 Thirst 27 4.1 4.1 signal
293 Product Residue Present 8 4.0 4.1 signal
294 Personality Change 14 4.0 4.0 signal
295 Hypotension 299 4.0 4.1 signal
296 Areflexia 4 4.0 4.0 signal
297 Electric Shock Sensation 4 4.0 4.0 signal
298 Delusion 23 4.0 4.0 signal
299 Bruxism 8 4.0 4.0 signal
300 Poor Quality Device Used 13 4.0 4.0 signal
301 Product Dispensing Error 32 3.9 4.0 signal
302 Peripheral Coldness 20 3.9 3.9 signal
303 Akinesia 3 3.9 3.9 no signal
304 Cystic Fibrosis 8 3.9 3.9 signal
305 Drug Screen False Positive 4 3.8 3.8 signal
306 Drug Tolerance Decreased 4 3.8 3.8 signal
307 Product Contamination 5 3.8 3.8 signal
308 Insurance Issue 21 3.8 3.8 signal
309 Product Physical Issue 28 3.8 3.8 signal
310 Mydriasis 18 3.8 3.8 signal
311 Salivary Hypersecretion 14 3.8 3.8 signal
312 Toxicity To Various Agents 235 3.8 3.8 signal
313 Seizure 160 3.7 3.8 signal
314 Galactorrhoea 9 3.7 3.7 signal
315 Paranoia 24 3.7 3.7 signal
316 Pharyngitis Streptococcal 15 3.7 3.7 signal
317 Accidental Overdose 50 3.7 3.7 signal
318 Depressed Mood 72 3.7 3.7 signal
319 Paradoxical Drug Reaction 5 3.7 3.7 signal
320 Heart Rate Decreased 48 3.6 3.7 signal
321 Wrong Product Administered 9 3.6 3.6 signal
322 Cardiac Failure Acute 9 3.6 3.6 signal
323 Drug Effect Less Than Expected 19 3.6 3.6 signal
324 Craniocerebral Injury 4 3.6 3.6 signal
325 Infusion Site Erythema 11 3.6 3.6 signal
326 Troponin Increased 10 3.6 3.6 signal
327 Obesity 21 3.5 3.5 signal
328 Atrioventricular Block Second Degree 4 3.5 3.5 signal
329 Prescription Drug Used Without A Prescription 8 3.5 3.5 signal
330 Apathy 19 3.5 3.5 signal
331 Hallucination 98 3.5 3.5 signal
332 Overweight 7 3.5 3.5 signal
333 Arrhythmia 62 3.5 3.5 signal
334 Dysarthria 49 3.5 3.5 signal
335 Hypersomnia 37 3.5 3.5 signal
336 Mental Disorder 56 3.4 3.5 signal
337 Epilepsy 39 3.4 3.4 signal
338 Brain Oedema 16 3.4 3.4 signal
339 Polydipsia 5 3.4 3.4 signal
340 Miosis 10 3.4 3.4 signal
341 Muscle Rigidity 15 3.4 3.4 signal
342 Expired Device Used 4 3.3 3.3 signal
343 Acute Psychosis 3 3.3 3.3 no signal
344 Hyperventilation 7 3.2 3.2 signal
345 Unresponsive To Stimuli 31 3.2 3.2 signal
346 Atrioventricular Block Complete 8 3.2 3.2 signal
347 Decreased Interest 7 3.2 3.2 signal
348 Impaired Quality Of Life 17 3.2 3.2 signal
349 Energy Increased 7 3.2 3.2 signal
350 No Adverse Event 208 3.1 3.2 signal
351 Eye Movement Disorder 8 3.1 3.1 signal
352 Left Ventricular Hypertrophy 5 3.1 3.1 signal
353 Obstructive Airways Disorder 13 3.1 3.1 signal
354 Concussion 9 3.1 3.1 signal
355 Cerebral Ischaemia 6 3.1 3.1 signal
356 Apnoea 9 3.1 3.1 signal
357 Formication 8 3.1 3.1 signal
358 Drug Interaction 182 3.1 3.1 signal
359 Drug Level Increased 19 3.1 3.1 signal
360 Rebound Effect 13 3.1 3.1 signal
361 Sensitivity To Weather Change 6 3.1 3.1 signal
362 Infusion Site Swelling 7 3.0 3.1 signal
363 Product Supply Issue 8 3.0 3.0 signal
364 Intentional Dose Omission 31 3.0 3.0 signal
365 Tachycardia 100 3.0 3.0 signal
366 Muscle Twitching 26 3.0 3.0 signal
367 Thinking Abnormal 21 3.0 3.0 signal
368 Mental Impairment 27 3.0 3.0 signal
369 Dyskinesia 45 3.0 3.0 signal
370 Blood Pressure Systolic Decreased 5 3.0 3.0 signal
371 Frustration 4 3.0 3.0 no signal
372 Impaired Gastric Emptying 14 2.9 2.9 signal
373 Drug Effect Delayed 5 2.9 2.9 signal
374 Treatment Failure 89 2.9 2.9 signal
375 Psychiatric Symptom 8 2.9 2.9 signal
376 Insomnia 288 2.9 3.0 signal
377 Streptococcal Infection 6 2.9 2.9 signal
378 Coma 51 2.9 2.9 signal
379 Catheter Site Infection 4 2.9 2.9 no signal
380 Product Formulation Issue 7 2.8 2.8 signal
381 Sinus Tachycardia 15 2.8 2.8 signal
382 Rhinovirus Infection 4 2.8 2.8 no signal
383 Sleep Disorder 72 2.8 2.8 signal
384 Brain Fog 15 2.8 2.8 signal
385 Product Adhesion Issue 36 2.7 2.7 signal
386 Suspected Counterfeit Product 4 2.7 2.7 no signal
387 Drug Effect Decreased 55 2.7 2.7 signal
388 Myositis 9 2.7 2.7 signal
389 Inappropriate Schedule Of Drug Administration 72 2.7 2.7 signal
390 Blindness Unilateral 14 2.7 2.7 signal
391 Blood Creatine Phosphokinase Increased 29 2.7 2.7 signal
392 Sluggishness 10 2.6 2.6 signal
393 Substance Abuse 8 2.6 2.6 signal
394 Nightmare 34 2.6 2.6 signal
395 Panic Reaction 7 2.6 2.6 signal
396 Euphoric Mood 10 2.6 2.6 signal
397 Application Site Pruritus 22 2.6 2.6 signal
398 Benign Prostatic Hyperplasia 5 2.6 2.6 no signal
399 Urinary Retention 32 2.6 2.6 signal
400 Fear 26 2.6 2.6 signal
401 Product Use Issue 179 2.6 2.6 signal
402 Rash Pustular 7 2.6 2.6 signal
403 Major Depression 7 2.6 2.6 signal
404 Completed Suicide 80 2.5 2.6 signal
405 Urinary Incontinence 28 2.5 2.5 signal
406 Incontinence 10 2.5 2.5 signal
407 Encephalopathy 23 2.5 2.5 signal
408 Gastroenteritis Viral 17 2.5 2.5 signal
409 Anxiety 267 2.5 2.6 signal
410 Eating Disorder 20 2.5 2.5 signal
411 Device Physical Property Issue 7 2.5 2.5 signal
412 Food Allergy 7 2.5 2.5 signal
413 Ataxia 11 2.5 2.5 signal
414 Parkinsonism 9 2.5 2.5 signal
415 Staphylococcal Bacteraemia 4 2.5 2.5 no signal
416 Weight Increased 203 2.4 2.5 signal
417 Ear Infection 24 2.4 2.4 signal
418 Hunger 12 2.4 2.4 signal
419 Electrocardiogram Abnormal 7 2.4 2.4 signal
420 Poor Quality Sleep 19 2.4 2.4 signal
421 Status Epilepticus 10 2.4 2.4 signal
422 Blood Thyroid Stimulating Hormone Decreased 4 2.4 2.4 no signal
423 Exercise Tolerance Decreased 5 2.3 2.3 no signal
424 Granulocytopenia 5 2.3 2.3 no signal
425 Sensory Disturbance 14 2.3 2.3 signal
426 Blood Uric Acid Increased 5 2.3 2.3 no signal
427 Hair Growth Abnormal 6 2.3 2.3 no signal
428 Application Site Pain 19 2.3 2.3 signal
429 Convulsion 50 2.3 2.3 signal
430 Sexual Dysfunction 10 2.3 2.3 signal
431 Grand Mal Convulsion 8 2.3 2.3 signal
432 Product Administration Error 17 2.3 2.3 signal
433 Tardive Dyskinesia 24 2.3 2.3 signal
434 Loss Of Consciousness 108 2.3 2.3 signal
435 Product Use Complaint 13 2.2 2.3 signal
436 Feeling Jittery 16 2.2 2.2 signal
437 Injection Site Vesicles 5 2.2 2.2 no signal
438 Type 1 Diabetes Mellitus 5 2.2 2.2 no signal
439 Visual Field Defect 6 2.2 2.2 no signal
440 Treatment Noncompliance 45 2.2 2.2 signal
441 Drug Ineffective For Unapproved Indication 46 2.2 2.2 signal
442 Cyanosis 13 2.2 2.2 signal
443 Device Information Output Issue 6 2.2 2.2 no signal
444 Amylase Increased 3 2.2 2.2 no signal
445 Coeliac Disease 8 2.2 2.2 signal
446 Device Breakage 32 2.2 2.2 signal
447 Haemorrhoidal Haemorrhage 4 2.2 2.2 no signal
448 Mucous Stools 4 2.2 2.2 no signal
449 Renal Cell Carcinoma 4 2.2 2.2 no signal
450 Fluid Intake Reduced 4 2.2 2.2 no signal
451 Delirium 28 2.2 2.2 signal
452 Decreased Appetite 187 2.2 2.2 signal
453 Blepharospasm 5 2.2 2.2 no signal
454 Overdose 174 2.2 2.2 signal
455 Retching 17 2.1 2.1 signal
456 Autoimmune Thyroiditis 3 2.1 2.1 no signal
457 Expired Drug Administered 4 2.1 2.1 no signal
458 Cognitive Disorder 37 2.1 2.1 signal
459 Panic Attack 29 2.1 2.1 signal
460 Dermatitis Contact 9 2.1 2.1 signal
461 Cardiotoxicity 7 2.1 2.1 no signal
462 Infusion Site Pain 10 2.1 2.1 signal
463 Drug Dispensing Error 12 2.1 2.1 signal
464 Incoherent 5 2.1 2.1 no signal
465 Weight Fluctuation 8 2.1 2.1 no signal
466 Depression 175 2.1 2.1 signal
467 Blood Lactic Acid Increased 4 2.0 2.0 no signal
468 Skin Haemorrhage 11 2.0 2.0 signal
469 Hyperhidrosis 98 2.0 2.1 signal
470 Mental Status Changes 21 2.0 2.0 signal
471 Nystagmus 4 2.0 2.0 no signal
472 Decreased Activity 8 2.0 2.0 no signal
473 Product Taste Abnormal 10 2.0 2.0 no signal
474 Nonspecific Reaction 4 2.0 2.0 no signal
475 Blood Triglycerides Increased 13 2.0 2.0 no signal
476 Off Label Use 630 1.9 2.0 no signal
477 Blood Testosterone Decreased 5 1.9 1.9 no signal
478 Ventricular Fibrillation 8 1.9 1.9 no signal
479 Hypertensive Crisis 8 1.9 1.9 no signal
480 Movement Disorder 23 1.9 1.9 no signal
481 Accidental Exposure 3 1.9 1.9 no signal
482 Liquid Product Physical Issue 5 1.9 1.9 no signal
483 Circulatory Collapse 12 1.9 1.9 no signal
484 Cardiogenic Shock 10 1.9 1.9 no signal
485 Brain Injury 7 1.9 1.9 no signal
486 Diplopia 18 1.9 1.9 no signal
487 Pulmonary Oedema 31 1.9 1.9 no signal
488 Therapeutic Response Shortened 22 1.9 1.9 no signal
489 Metabolic Disorder 4 1.8 1.8 no signal
490 Skin Fissures 13 1.8 1.8 no signal
491 Device Leakage 29 1.8 1.8 no signal
492 Drug Level Decreased 7 1.8 1.8 no signal
493 Dermatitis Atopic 34 1.8 1.8 no signal
494 Extrapyramidal Disorder 17 1.8 1.8 no signal
495 Feeling Drunk 5 1.8 1.8 no signal
496 Wrong Technique In Product Usage Process 135 1.8 1.8 no signal
497 Head Injury 21 1.8 1.8 no signal
498 Dry Mouth 53 1.8 1.8 no signal
499 End Stage Renal Disease 12 1.7 1.7 no signal
500 Skin Laceration 7 1.7 1.7 no signal
501 Scoliosis 4 1.7 1.7 no signal
502 Coordination Abnormal 9 1.7 1.7 no signal
503 Pulmonary Haemorrhage 5 1.7 1.7 no signal
504 Condition Aggravated 193 1.7 1.7 no signal
505 Eczema 32 1.7 1.7 no signal
506 Poisoning 8 1.7 1.7 no signal
507 Hypertension 134 1.7 1.7 no signal
508 Hypophagia 16 1.7 1.7 no signal
509 Therapy Cessation 32 1.7 1.7 no signal
510 Paralysis 9 1.7 1.7 no signal
511 Transplant Rejection 5 1.7 1.7 no signal
512 Gastrointestinal Disorder 55 1.7 1.7 no signal
513 Hepatitis Acute 4 1.7 1.7 no signal
514 Cardiac Flutter 4 1.7 1.7 no signal
515 Drug Ineffective 813 1.7 1.7 no signal
516 Renal Tubular Necrosis 6 1.6 1.6 no signal
517 Feeling Cold 17 1.6 1.6 no signal
518 Therapeutic Product Effect Decreased 27 1.6 1.6 no signal
519 Therapy Non-responder 27 1.6 1.6 no signal
520 Feeding Disorder 12 1.6 1.6 no signal
521 Prescribed Underdose 12 1.6 1.6 no signal
522 Therapeutic Response Unexpected 27 1.6 1.6 no signal
523 Lactic Acidosis 19 1.6 1.6 no signal
524 Product Prescribing Issue 12 1.6 1.6 no signal
525 Temperature Intolerance 6 1.6 1.6 no signal
526 Dizziness 291 1.6 1.6 no signal
527 Poor Venous Access 6 1.6 1.6 no signal
528 Scratch 6 1.6 1.6 no signal
529 Ventricular Extrasystoles 6 1.5 1.5 no signal
530 Sleep Apnoea Syndrome 11 1.5 1.5 no signal
531 Drug Dose Omission By Device 44 1.5 1.5 no signal
532 Drug Dose Omission 96 1.5 1.5 no signal
533 Product Dose Omission Issue 163 1.5 1.5 no signal
534 Drug Intolerance 55 1.5 1.5 no signal
535 Blood Lactate Dehydrogenase Increased 9 1.5 1.5 no signal
536 Product Distribution Issue 5 1.5 1.5 no signal
537 Loss Of Libido 5 1.5 1.5 no signal
538 Sleep Disorder Due To A General Medical Condition 9 1.5 1.5 no signal
539 Heart Rate Increased 55 1.5 1.5 no signal
540 Haemophagocytic Lymphohistiocytosis 4 1.5 1.5 no signal
541 Product Use In Unapproved Indication 135 1.5 1.5 no signal
542 Sensitive Skin 4 1.5 1.5 no signal
543 Product Packaging Quantity Issue 6 1.5 1.5 no signal
544 Developmental Delay 5 1.5 1.5 no signal
545 Product Prescribing Error 13 1.5 1.5 no signal
546 Constipation 118 1.5 1.5 no signal
547 Oral Disorder 4 1.5 1.5 no signal
548 Arthropod Bite 4 1.5 1.5 no signal
549 Ventricular Tachycardia 9 1.5 1.5 no signal
550 Viral Infection 18 1.5 1.5 no signal
551 Product Packaging Issue 5 1.4 1.4 no signal
552 Palpitations 63 1.4 1.4 no signal
553 Poisoning Deliberate 5 1.4 1.4 no signal
554 Dermatitis 11 1.4 1.4 no signal
555 Blood Pressure Increased 81 1.4 1.4 no signal
556 Disorientation 21 1.4 1.4 no signal
557 Discomfort 32 1.4 1.4 no signal
558 Acidosis 4 1.4 1.4 no signal
559 Speech Disorder 27 1.4 1.4 no signal
560 Feeling Abnormal 123 1.4 1.4 no signal
561 Illness 51 1.4 1.4 no signal
562 Application Site Rash 7 1.4 1.4 no signal
563 Erectile Dysfunction 13 1.4 1.4 no signal
564 Loss Of Personal Independence In Daily Activities 24 1.4 1.4 no signal
565 Body Temperature Decreased 5 1.3 1.4 no signal
566 Low Birth Weight Baby 4 1.3 1.3 no signal
567 Myoclonus 6 1.3 1.3 no signal
568 Tremor 83 1.3 1.3 no signal
569 Hypotonia 5 1.3 1.3 no signal
570 Product Dose Omission 33 1.3 1.3 no signal
571 Leukocytosis 9 1.3 1.3 no signal
572 Therapeutic Response Decreased 30 1.3 1.3 no signal
573 Glomerular Filtration Rate Decreased 6 1.3 1.3 no signal
574 Cardiac Arrest 41 1.3 1.3 no signal
575 Schizophrenia 6 1.3 1.3 no signal
576 Dry Throat 5 1.3 1.3 no signal
577 Influenza 55 1.3 1.3 no signal
578 Adverse Drug Reaction 44 1.3 1.3 no signal
579 Rib Fracture 10 1.3 1.3 no signal
580 Vomiting 228 1.3 1.3 no signal
581 Staphylococcal Infection 16 1.3 1.3 no signal
582 Shock 11 1.3 1.3 no signal
583 Photophobia 9 1.3 1.3 no signal
584 Nasal Congestion 28 1.3 1.3 no signal
585 Intentional Product Use Issue 42 1.3 1.3 no signal
586 Adverse Event 44 1.3 1.3 no signal
587 Abdominal Pain Upper 98 1.3 1.3 no signal
588 Hereditary Angioedema 5 1.3 1.3 no signal
589 Blood Urea Increased 8 1.3 1.3 no signal
590 Metabolic Acidosis 15 1.3 1.3 no signal
591 Pseudomonas Infection 4 1.3 1.3 no signal
592 Product Communication Issue 4 1.3 1.3 no signal
593 Vitamin D Decreased 4 1.3 1.3 no signal
594 Therapeutic Product Effect Incomplete 33 1.3 1.3 no signal
595 Hysterectomy 4 1.2 1.2 no signal
596 Intentional Product Misuse 40 1.2 1.2 no signal
597 Device Adhesion Issue 7 1.2 1.2 no signal
598 Cold Sweat 8 1.2 1.2 no signal
599 Migraine 43 1.2 1.2 no signal
600 Headache 283 1.2 1.2 no signal
601 Fatigue 351 1.2 1.2 no signal
602 Malnutrition 5 1.2 1.2 no signal
603 Respiratory Rate Increased 4 1.2 1.2 no signal
604 Oropharyngeal Discomfort 4 1.2 1.2 no signal
605 Nervous System Disorder 14 1.2 1.2 no signal
606 Product Dose Omission In Error 12 1.2 1.2 no signal
607 Hospitalisation 68 1.2 1.2 no signal
608 Dysstasia 13 1.2 1.2 no signal
609 Wrong Drug Administered 4 1.2 1.2 no signal
610 Dehydration 59 1.2 1.2 no signal
611 White Blood Cell Count Increased 17 1.2 1.2 no signal
612 Device Use Error 15 1.2 1.2 no signal
613 Feeling Hot 27 1.2 1.2 no signal
614 Wrong Technique In Device Usage Process 20 1.2 1.2 no signal
615 Device Issue 38 1.2 1.2 no signal
616 Increased Tendency To Bruise 4 1.2 1.2 no signal
617 Weight Decreased 121 1.2 1.2 no signal
618 Medication Error 24 1.2 1.2 no signal
619 Multiple Organ Dysfunction Syndrome 12 1.2 1.2 no signal
620 Sinusitis 44 1.1 1.1 no signal
621 Mouth Ulceration 9 1.1 1.1 no signal
622 Epistaxis 32 1.1 1.1 no signal
623 Seasonal Allergy 6 1.1 1.1 no signal
624 Unevaluable Event 32 1.1 1.1 no signal
625 Clostridium Difficile Infection 9 1.1 1.1 no signal
626 Amnesia 27 1.1 1.1 no signal
627 Choking 8 1.1 1.1 no signal
628 Flushing 42 1.1 1.1 no signal
629 Pollakiuria 17 1.1 1.1 no signal
630 Ileus 5 1.1 1.1 no signal
631 Ligament Sprain 4 1.1 1.1 no signal
632 Incorrect Dose Administered 91 1.1 1.1 no signal
633 Blood Pressure Diastolic Decreased 3 1.1 1.1 no signal
634 Chronic Kidney Disease 31 1.1 1.1 no signal
635 Disability 8 1.1 1.1 no signal
636 No Therapeutic Response 5 1.1 1.1 no signal
637 Libido Decreased 5 1.1 1.1 no signal
638 Neurotoxicity 7 1.1 1.1 no signal
639 Upper Limb Fracture 8 1.1 1.1 no signal
640 Respiratory Arrest 11 1.1 1.1 no signal
641 Motor Dysfunction 4 1.1 1.1 no signal
642 Diabetes Mellitus Inadequate Control 7 1.1 1.1 no signal
643 Emotional Distress 48 1.1 1.1 no signal
644 Anaphylactic Shock 10 1.0 1.0 no signal
645 Product Administered At Inappropriate Site 7 1.0 1.0 no signal
646 Deafness 10 1.0 1.0 no signal
647 Joint Dislocation 4 1.0 1.0 no signal
648 Blood Albumin Decreased 3 1.0 1.0 no signal
649 Complication Associated With Device 5 1.0 1.0 no signal
650 Anhedonia 10 1.0 1.0 no signal
651 Adverse Reaction 5 1.0 1.0 no signal
652 Diabetic Ketoacidosis 9 1.0 1.0 no signal
653 Stress 27 1.0 1.0 no signal
654 Asthma 42 1.0 1.0 no signal
655 Irritable Bowel Syndrome 8 1.0 1.0 no signal
656 Night Sweats 12 1.0 1.0 no signal
657 Chest Pain 69 1.0 1.0 no signal
658 Pain Of Skin 10 1.0 1.0 no signal
659 Sinus Congestion 5 1.0 1.0 no signal
660 Aspiration 4 1.0 1.0 no signal
661 Inappropriate Schedule Of Product Administration 65 1.0 1.0 no signal
662 Asphyxia 3 1.0 1.0 no signal
663 Lower Limb Fracture 7 1.0 1.0 no signal
664 Eye Disorder 12 1.0 1.0 no signal
665 Abdominal Pain 85 1.0 1.0 no signal
666 Gastrointestinal Pain 4 1.0 1.0 no signal
667 Pruritus Generalised 8 1.0 1.0 no signal
668 Eye Pain 20 1.0 1.0 no signal
669 Foot Deformity 4 1.0 1.0 no signal
670 Dysphagia 34 1.0 1.0 no signal
671 Scab 4 0.9 0.9 no signal
672 Drug Effect Incomplete 13 0.9 0.9 no signal
673 Cholecystectomy 4 0.9 0.9 no signal
674 Impaired Driving Ability 4 0.9 0.9 no signal
675 Nephrolithiasis 16 0.9 0.9 no signal
676 Activities Of Daily Living Impaired 7 0.9 0.9 no signal
677 Tinnitus 16 0.9 0.9 no signal
678 Abdominal Discomfort 58 0.9 0.9 no signal
679 Oropharyngeal Pain 32 0.9 0.9 no signal
680 Hypokinesia 5 0.9 0.9 no signal
681 Nervousness 18 0.9 0.9 no signal
682 Paraesthesia 54 0.9 0.9 no signal
683 Hypoxia 12 0.9 0.9 no signal
684 Head Discomfort 6 0.9 0.9 no signal
685 Fall 113 0.9 0.9 no signal
686 Anal Incontinence 3 0.9 0.9 no signal
687 Rhabdomyolysis 14 0.9 0.9 no signal
688 Hyperlipidaemia 4 0.9 0.9 no signal
689 Therapy Interrupted 23 0.9 0.9 no signal
690 Renal Injury 10 0.9 0.9 no signal
691 Blood Pressure Fluctuation 8 0.9 0.9 no signal
692 Gait Inability 11 0.9 0.9 no signal
693 Toxic Epidermal Necrolysis 5 0.9 0.9 no signal
694 Lip Swelling 11 0.9 0.9 no signal
695 Spinal Operation 4 0.9 0.9 no signal
696 Fungal Infection 11 0.9 0.9 no signal
697 Restless Legs Syndrome 6 0.9 0.9 no signal
698 Underdose 24 0.9 0.9 no signal
699 Nausea 258 0.9 0.9 no signal
700 Hypokalaemia 15 0.9 0.9 no signal
701 Blood Thyroid Stimulating Hormone Increased 3 0.9 0.9 no signal
702 Generalised Oedema 4 0.9 0.9 no signal
703 Eye Swelling 12 0.9 0.9 no signal
704 Economic Problem 5 0.9 0.9 no signal
705 Hypersensitivity 60 0.9 0.9 no signal
706 Appendicitis 3 0.9 0.9 no signal
707 Bronchitis 24 0.9 0.9 no signal
708 Cardiomegaly 4 0.9 0.9 no signal
709 Blood Sodium Decreased 6 0.9 0.9 no signal
710 Rash Macular 11 0.8 0.8 no signal
711 Foot Fracture 6 0.8 0.8 no signal
712 Pneumothorax 5 0.8 0.8 no signal
713 Acne 24 0.8 0.8 no signal
714 Incorrect Dose Administered By Device 8 0.8 0.8 no signal
715 Urticaria 52 0.8 0.8 no signal
716 Angina Pectoris 9 0.8 0.8 no signal
717 Vertigo 19 0.8 0.8 no signal
718 Drug Resistance 8 0.8 0.8 no signal
719 Rhinorrhoea 20 0.8 0.8 no signal
720 Muscle Tightness 5 0.8 0.8 no signal
721 Hypoglycaemia 15 0.8 0.8 no signal
722 Nasopharyngitis 57 0.8 0.8 no signal
723 Ear Pain 6 0.8 0.8 no signal
724 Device Delivery System Issue 8 0.8 0.8 no signal
725 Covid-19 54 0.8 0.8 no signal
726 Skin Discolouration 14 0.8 0.8 no signal
727 Pulmonary Congestion 4 0.8 0.8 no signal
728 Extra Dose Administered 12 0.8 0.8 no signal
729 Blood Cholesterol Increased 14 0.8 0.8 no signal
730 Vision Blurred 41 0.8 0.8 no signal
731 Ocular Hyperaemia 14 0.8 0.8 no signal
732 Sars-cov-2 Test Positive 4 0.8 0.8 no signal
733 Gastrooesophageal Reflux Disease 24 0.8 0.8 no signal
734 Rash Erythematous 14 0.8 0.8 no signal
735 Dysuria 11 0.8 0.8 no signal
736 Rash 129 0.8 0.8 no signal
737 Gastrointestinal Haemorrhage 25 0.8 0.8 no signal
738 Pregnancy 6 0.8 0.8 no signal
739 Rash Pruritic 16 0.8 0.8 no signal
740 Type 2 Diabetes Mellitus 10 0.8 0.8 no signal
741 Incorrect Product Administration Duration 6 0.8 0.8 no signal
742 Surgery 17 0.8 0.8 no signal
743 Musculoskeletal Discomfort 5 0.8 0.8 no signal
744 Injection Site Discomfort 3 0.8 0.8 no signal
745 Dry Skin 38 0.8 0.8 no signal
746 Neuralgia 7 0.8 0.8 no signal
747 Injection Site Urticaria 7 0.8 0.8 no signal
748 Device Occlusion 4 0.8 0.8 no signal
749 Road Traffic Accident 12 0.8 0.8 no signal
750 Haemoptysis 8 0.8 0.8 no signal
751 Pain In Jaw 8 0.8 0.8 no signal
752 Malaise 124 0.8 0.8 no signal
753 Product Complaint 7 0.8 0.8 no signal
754 Abasia 7 0.7 0.7 no signal
755 Paraesthesia Oral 4 0.7 0.7 no signal
756 Glycosylated Haemoglobin Increased 7 0.7 0.7 no signal
757 Body Height Decreased 3 0.7 0.7 no signal
758 Chest Discomfort 28 0.7 0.7 no signal
759 Cholelithiasis 9 0.7 0.7 no signal
760 Impaired Healing 9 0.7 0.7 no signal
761 Eye Pruritus 9 0.7 0.7 no signal
762 Conjunctivitis 5 0.7 0.7 no signal
763 Immunodeficiency 4 0.7 0.7 no signal
764 Injection Site Mass 10 0.7 0.7 no signal
765 Contusion 26 0.7 0.7 no signal
766 Hepatic Function Abnormal 10 0.7 0.7 no signal
767 Stevens-johnson Syndrome 6 0.7 0.7 no signal
768 Bacterial Infection 5 0.7 0.7 no signal
769 Pancreatitis Acute 6 0.7 0.7 no signal
770 Drug Withdrawal Syndrome Neonatal 4 0.7 0.7 no signal
771 Rash Papular 6 0.7 0.7 no signal
772 Tubulointerstitial Nephritis 5 0.7 0.7 no signal
773 Respiratory Disorder 8 0.7 0.7 no signal
774 Injection Site Reaction 18 0.7 0.7 no signal
775 Renal Failure 35 0.7 0.7 no signal
776 Swelling Face 17 0.7 0.7 no signal
777 Alanine Aminotransferase Increased 16 0.7 0.7 no signal
778 Respiratory Failure 19 0.7 0.7 no signal
779 Upper Respiratory Tract Infection 12 0.7 0.7 no signal
780 Abdominal Distension 27 0.7 0.7 no signal
781 Glaucoma 5 0.7 0.7 no signal
782 Confusional State 42 0.7 0.7 no signal
783 Oedema 14 0.7 0.7 no signal
784 Limb Discomfort 8 0.7 0.7 no signal
785 Cough 72 0.7 0.7 no signal
786 Renal Disorder 12 0.7 0.7 no signal
787 Muscle Spasms 47 0.7 0.7 no signal
788 Fluid Retention 13 0.7 0.7 no signal
789 Blood Iron Decreased 3 0.7 0.7 no signal
790 Sickle Cell Anaemia With Crisis 4 0.7 0.7 no signal
791 Cataract 15 0.7 0.7 no signal
792 Blood Pressure Abnormal 5 0.7 0.7 no signal
793 Sinus Disorder 5 0.7 0.7 no signal
794 Adrenal Insufficiency 3 0.7 0.7 no signal
795 Device Deployment Issue 3 0.7 0.7 no signal
796 Localised Infection 6 0.7 0.7 no signal
797 Hyperglycaemia 9 0.7 0.7 no signal
798 Flatulence 14 0.7 0.7 no signal
799 Device Defective 4 0.7 0.7 no signal
800 Blood Potassium Increased 4 0.7 0.7 no signal
801 Pancreatitis 13 0.7 0.7 no signal
802 Back Disorder 4 0.7 0.7 no signal
803 Asthenia 92 0.7 0.7 no signal
804 Photosensitivity Reaction 4 0.7 0.7 no signal
805 Lower Respiratory Tract Infection 11 0.7 0.7 no signal
806 Pyrexia 84 0.7 0.6 no signal
807 Product Preparation Error 5 0.6 0.6 no signal
808 Peripheral Swelling 37 0.6 0.6 no signal
809 Expired Product Administered 8 0.6 0.6 no signal
810 Pneumonia Aspiration 6 0.6 0.6 no signal
811 Injection Site Extravasation 3 0.6 0.6 no signal
812 Amenorrhoea 4 0.6 0.6 no signal
813 Drug Effective For Unapproved Indication 7 0.6 0.6 no signal
814 Circumstance Or Information Capable Of Leading To Medication Error 8 0.6 0.6 no signal
815 Injection Site Swelling 18 0.6 0.6 no signal
816 Cardiac Failure 19 0.6 0.6 no signal
817 Transient Ischaemic Attack 8 0.6 0.6 no signal
818 Face Oedema 4 0.6 0.6 no signal
819 Pruritus 89 0.6 0.6 no signal
820 Gait Disturbance 45 0.6 0.6 no signal
821 Joint Injury 5 0.6 0.6 no signal
822 Scar 4 0.6 0.6 no signal
823 Oxygen Saturation Decreased 13 0.6 0.6 no signal
824 Blood Potassium Decreased 7 0.6 0.6 no signal
825 Memory Impairment 32 0.6 0.6 no signal
826 Drug Hypersensitivity 45 0.6 0.6 no signal
827 Injection Site Induration 3 0.6 0.6 no signal
828 Aphasia 7 0.6 0.6 no signal
829 Acute Kidney Injury 35 0.6 0.6 no signal
830 Dysmenorrhoea 3 0.6 0.6 no signal
831 Rash Generalised 6 0.6 0.6 no signal
832 Device Difficult To Use 15 0.6 0.6 no signal
833 Acute Respiratory Distress Syndrome 4 0.6 0.6 no signal
834 Pneumonia 73 0.6 0.6 no signal
835 Transaminases Increased 5 0.6 0.6 no signal
836 Sneezing 5 0.6 0.6 no signal
837 Gout 4 0.6 0.6 no signal
838 Limb Injury 6 0.6 0.6 no signal
839 Toothache 4 0.6 0.6 no signal
840 Hepatic Enzyme Increased 15 0.6 0.6 no signal
841 Hypoaesthesia 33 0.6 0.6 no signal
842 Hypothyroidism 7 0.6 0.6 no signal
843 Cystitis 7 0.6 0.6 no signal
844 General Physical Health Deterioration 25 0.6 0.6 no signal
845 Pain In Extremity 64 0.6 0.6 no signal
846 Abnormal Dreams 6 0.6 0.6 no signal
847 Complication Of Device Insertion 4 0.6 0.6 no signal
848 Inflammation 11 0.6 0.6 no signal
849 Drug Withdrawal Syndrome 19 0.6 0.6 no signal
850 Blister 12 0.6 0.6 no signal
851 Injection Site Pain 65 0.6 0.6 no signal
852 Cardio-respiratory Arrest 9 0.6 0.6 no signal
853 Diarrhoea 137 0.6 0.6 no signal
854 Hot Flush 16 0.6 0.6 no signal
855 White Blood Cell Count Decreased 23 0.6 0.6 no signal
856 Productive Cough 10 0.6 0.6 no signal
857 Muscular Weakness 24 0.6 0.6 no signal
858 Accidental Exposure To Product 21 0.6 0.6 no signal
859 Needle Issue 6 0.6 0.6 no signal
860 Acute Respiratory Failure 4 0.6 0.6 no signal
861 Herpes Zoster 12 0.6 0.6 no signal
862 Aspartate Aminotransferase Increased 11 0.6 0.6 no signal
863 Oral Herpes 4 0.6 0.6 no signal
864 Dysphonia 12 0.6 0.5 no signal
865 Skin Exfoliation 17 0.5 0.5 no signal
866 Cerebral Infarction 5 0.5 0.5 no signal
867 Chills 24 0.5 0.5 no signal
868 Kidney Infection 4 0.5 0.5 no signal
869 Dyspepsia 20 0.5 0.5 no signal
870 Swelling 19 0.5 0.5 no signal
871 Liver Disorder 9 0.5 0.5 no signal
872 Infection 29 0.5 0.5 no signal
873 Blood Alkaline Phosphatase Increased 5 0.5 0.5 no signal
874 Haematocrit Decreased 4 0.5 0.5 no signal
875 Anaphylactic Reaction 11 0.5 0.5 no signal
876 Haematochezia 11 0.5 0.5 no signal
877 Lymphadenopathy 7 0.5 0.5 no signal
878 Ill-defined Disorder 12 0.5 0.5 no signal
879 Eye Irritation 11 0.5 0.5 no signal
880 Haematemesis 5 0.5 0.5 no signal
881 Neck Pain 11 0.5 0.5 no signal
882 Balance Disorder 17 0.5 0.5 no signal
883 Oedema Peripheral 24 0.5 0.5 no signal
884 Body Temperature Increased 4 0.5 0.5 no signal
885 Visual Impairment 24 0.5 0.5 no signal
886 Skin Ulcer 5 0.5 0.5 no signal
887 Ankle Fracture 3 0.5 0.5 no signal
888 Respiratory Tract Infection 5 0.5 0.5 no signal
889 Swollen Tongue 6 0.5 0.5 no signal
890 Renal Impairment 16 0.5 0.5 no signal
891 Drug Dependence 31 0.5 0.5 no signal
892 Gastritis 5 0.5 0.5 no signal
893 Erythema 39 0.5 0.5 no signal
894 Disease Recurrence 9 0.5 0.5 no signal
895 Urinary Tract Infection 32 0.5 0.5 no signal
896 Dysgeusia 14 0.5 0.5 no signal
897 Impaired Work Ability 4 0.5 0.5 no signal
898 Dry Eye 9 0.5 0.5 no signal
899 Blood Glucose Increased 35 0.5 0.5 no signal
900 Dyspnoea 104 0.5 0.5 no signal
901 Diabetes Mellitus 14 0.5 0.5 no signal
902 Intervertebral Disc Protrusion 4 0.5 0.5 no signal
903 Stomatitis 11 0.5 0.5 no signal
904 Respiratory Distress 5 0.5 0.5 no signal
905 Procedural Pain 5 0.5 0.5 no signal
906 Oral Pain 4 0.5 0.5 no signal
907 Chromaturia 4 0.5 0.5 no signal
908 Complication Of Device Removal 3 0.5 0.5 no signal
909 Heart Rate Irregular 4 0.5 0.5 no signal
910 Blindness 7 0.5 0.5 no signal
911 Liver Function Test Abnormal 5 0.5 0.5 no signal
912 Injury 12 0.5 0.5 no signal
913 Influenza Like Illness 14 0.5 0.5 no signal
914 Cerebral Haemorrhage 6 0.4 0.4 no signal
915 Mobility Decreased 12 0.4 0.4 no signal
916 Blood Glucose Decreased 8 0.4 0.4 no signal
917 Hepatic Failure 5 0.4 0.4 no signal
918 Fibromyalgia 4 0.4 0.4 no signal
919 Pleural Effusion 10 0.4 0.4 no signal
920 Back Pain 38 0.4 0.4 no signal
921 Hypoacusis 7 0.4 0.4 no signal
922 Neutropenia 22 0.4 0.4 no signal
923 Rectal Haemorrhage 7 0.4 0.4 no signal
924 Septic Shock 7 0.4 0.4 no signal
925 Intestinal Obstruction 6 0.4 0.4 no signal
926 Ageusia 4 0.4 0.4 no signal
927 Cardiac Disorder 15 0.4 0.4 no signal
928 Neuropathy Peripheral 15 0.4 0.4 no signal
929 Angioedema 7 0.4 0.4 no signal
930 Haematoma 4 0.4 0.4 no signal
931 Blood Pressure Systolic Increased 3 0.4 0.4 no signal
932 Skin Irritation 7 0.4 0.4 no signal
933 Arthritis 12 0.4 0.4 no signal
934 Menstruation Irregular 4 0.4 0.4 no signal
935 Skin Disorder 5 0.4 0.4 no signal
936 Device Malfunction 10 0.4 0.4 no signal
937 Frequent Bowel Movements 4 0.4 0.4 no signal
938 Musculoskeletal Stiffness 13 0.4 0.4 no signal
939 Jaundice 4 0.4 0.4 no signal
940 Throat Tightness 4 0.4 0.4 no signal
941 Pain 91 0.4 0.4 no signal
942 Blood Bilirubin Increased 4 0.4 0.4 no signal
943 Drug Abuse 12 0.4 0.4 no signal
944 Lung Disorder 7 0.4 0.4 no signal
945 Renal Failure Acute 6 0.4 0.4 no signal
946 Psoriasis 18 0.4 0.4 no signal
947 Arthralgia 57 0.4 0.4 no signal
948 Dyspnoea Exertional 5 0.4 0.4 no signal
949 Exposure Via Skin Contact 3 0.4 0.4 no signal
950 Contraindicated Product Administered 4 0.4 0.4 no signal
951 Injection Site Erythema 16 0.3 0.3 no signal
952 Pulmonary Embolism 12 0.3 0.3 no signal
953 Arthropathy 7 0.3 0.3 no signal
954 Sepsis 14 0.3 0.3 no signal
955 Psoriatic Arthropathy 5 0.3 0.3 no signal
956 Abortion Spontaneous 5 0.3 0.3 no signal
957 Foetal Exposure During Pregnancy 10 0.3 0.3 no signal
958 Abdominal Pain Lower 3 0.3 0.3 no signal
959 Osteoarthritis 5 0.3 0.3 no signal
960 Myalgia 20 0.3 0.3 no signal
961 Product Storage Error 10 0.3 0.3 no signal
962 Gastric Disorder 4 0.3 0.3 no signal
963 Hyperkalaemia 4 0.3 0.3 no signal
964 Burning Sensation 8 0.3 0.3 no signal
965 Exposure During Pregnancy 7 0.3 0.3 no signal
966 Colitis Ulcerative 5 0.3 0.3 no signal
967 Throat Irritation 5 0.3 0.3 no signal
968 Cardiac Failure Congestive 9 0.3 0.3 no signal
969 Device Expulsion 7 0.3 0.3 no signal
970 Alopecia 21 0.3 0.3 no signal
971 Injection Site Pruritus 7 0.3 0.3 no signal
972 Injection Site Haemorrhage 8 0.3 0.3 no signal
973 Cerebrovascular Accident 17 0.3 0.3 no signal
974 Cellulitis 5 0.3 0.3 no signal
975 Neutrophil Count Decreased 4 0.3 0.3 no signal
976 Skin Burning Sensation 7 0.3 0.3 no signal
977 Chronic Obstructive Pulmonary Disease 5 0.3 0.3 no signal
978 Haemorrhage 10 0.3 0.3 no signal
979 Musculoskeletal Pain 5 0.3 0.3 no signal
980 Vaginal Haemorrhage 4 0.3 0.3 no signal
981 Disease Progression 11 0.2 0.2 no signal
982 Atrial Fibrillation 9 0.2 0.2 no signal
983 Device Dislocation 4 0.2 0.2 no signal
984 Deep Vein Thrombosis 6 0.2 0.2 no signal
985 Pancytopenia 5 0.2 0.2 no signal
986 Anaemia 17 0.2 0.2 no signal
987 Hyponatraemia 5 0.2 0.2 no signal
988 Wheezing 5 0.2 0.2 no signal
989 Platelet Count Decreased 9 0.2 0.2 no signal
990 Infusion Related Reaction 5 0.2 0.2 no signal
991 Neoplasm Malignant 5 0.2 0.2 no signal
992 Joint Swelling 9 0.2 0.2 no signal
993 Thrombosis 6 0.2 0.2 no signal
994 Myocardial Infarction 12 0.2 0.2 no signal
995 Haemoglobin Decreased 7 0.2 0.2 no signal
996 Maternal Exposure During Pregnancy 6 0.2 0.2 no signal
997 Injection Site Bruising 5 0.2 0.2 no signal
998 Death 54 0.2 0.2 no signal
999 Febrile Neutropenia 4 0.2 0.2 no signal
1000 Thrombocytopenia 6 0.1 0.1 no signal
1001 Rheumatoid Arthritis 5 0.1 0.1 no signal