Reaction

Periorbital Pain reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 792 reports · 36 co-occurring drugs

As of the last recalculation, Periorbital Pain appears in 792 FAERS reports alongside 36 co-occurring drug terms. The strongest observed disproportionality signal is CENEGERMIN-BKBJ (PRR 2,632.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Cenegermin-Bkbj	479	2,632.1	2,741.3
Carboxymethylcellulose Sodium	51	152.4	153.2
Moxifloxacin	40	78.5	78.8
Prednisolone Acetate	29	76.4	76.6
Lifitegrast	42	71.3	71.5
Moxifloxacin Hydrochloride	43	58.9	59.0
Timolol Maleate	16	43.3	43.4
Erythromycin	29	42.1	42.2
Doxyclycline Hyclate	26	41.5	41.5
Dorzolamide Hydrochloride And Timolol Maleate	11	37.1	37.1
Cyclobenzaprine Hydrochloride	11	32.6	32.6
Rosuvastatin Calcium	32	31.1	31.1
Pravastatin Sodium	21	28.6	28.6
Valacyclovir	41	27.2	27.2
Atorvastatin Calcium, Film Coated	56	22.5	22.5
Valacyclovir Hydrochloride	54	21.5	21.6
Hydroxyzine Hydrochloride	10	20.2	20.2
Hydroxyzine Hydrochloride Oral	10	20.2	20.2
Thyroid, Porcine	8	19.9	19.9
Brimonidine Tartrate	13	19.5	19.5
Botulinum Toxin Type A	9	19.3	19.3
Metoprolol Succinate Er Tablets	43	19.1	19.1
Biotin	22	19.0	19.0
Cetirizine Hcl	6	17.3	17.3
Faricimab	5	16.3	16.3
Estradiol Gel 0.1%	27	16.2	16.2
Estradiol Transdermal	27	16.2	16.2
Tobramycin Solution	7	15.4	15.5
Ranolazine	6	15.2	15.2
Tobramycin Sulfate	7	15.0	15.0
Azelastine	10	14.8	14.8
Icosapent Ethyl	4	12.4	12.4
Bimatoprost	12	11.1	11.1
Dupilumab	81	4.8	4.8
Adapalene	19	2.8	2.8
Salicylic Acid	5	2.5	2.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.