Reaction
Sick Sinus Syndrome reporting signals
As of the last recalculation, Sick Sinus Syndrome appears in 1,150 FAERS reports alongside 31 co-occurring drug terms. The strongest observed disproportionality signal is DIGOXIN (PRR 46.0).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Digoxin | 158 | 46.0 | 46.1 |
| Donepezil Hydrochloride | 58 | 30.1 | 30.1 |
| Amlodipine Besylate And Benazepril Hydrochloride | 15 | 29.8 | 29.8 |
| Diltiazem Hydrochloride | 49 | 26.7 | 26.8 |
| Atropine | 12 | 26.5 | 26.5 |
| Atropine Sulfate | 15 | 25.4 | 25.5 |
| Sotalol Hydrochloride | 21 | 23.3 | 23.3 |
| Enalapril Maleate | 29 | 21.7 | 21.7 |
| Diltiazem Hydrochloride Extended-Release Tablets | 13 | 20.9 | 20.9 |
| Timolol Maleate | 11 | 20.3 | 20.3 |
| Quinine | 9 | 19.1 | 19.2 |
| Lopinavir And Ritonavir | 14 | 18.9 | 18.9 |
| Meclizine Hcl 12.5Mg | 14 | 18.8 | 18.8 |
| Meclizine Hcl 25Mg | 14 | 18.8 | 18.8 |
| Meclizine Hcl 12.5 Mg | 14 | 18.8 | 18.8 |
| Meclizine Hcl 25 Mg | 14 | 18.8 | 18.8 |
| Warfarin Sodium | 46 | 18.7 | 18.7 |
| Sevoflurane | 8 | 17.5 | 17.6 |
| Nitroglycerin | 49 | 17.2 | 17.2 |
| Isosorbide Dinitrate | 18 | 16.9 | 16.9 |
| Meclizine | 14 | 15.7 | 15.7 |
| Ezetimibe And Simvastatin | 13 | 15.6 | 15.7 |
| Abacavir Sulfate | 8 | 15.0 | 15.0 |
| Amiodarone Hydrochloride | 9 | 14.6 | 14.7 |
| Human Insulin | 10 | 14.6 | 14.6 |
| Meclizine Hydrochloride | 14 | 13.1 | 13.1 |
| Glyburide | 17 | 12.9 | 12.9 |
| Rabeprazole Sodium | 19 | 12.8 | 12.8 |
| Thalidomide | 22 | 11.0 | 11.0 |
| Rivastigmine | 11 | 10.7 | 10.7 |
| Metformin Hcl | 27 | 9.0 | 9.0 |