Reaction
Skin Discomfort reporting signals
As of the last recalculation, Skin Discomfort appears in 2,624 FAERS reports alongside 24 co-occurring drug terms. The strongest observed disproportionality signal is ADAPALENE (PRR 55.3).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Adapalene | 861 | 55.3 | 55.6 |
| Sulfur | 44 | 42.1 | 42.3 |
| Salicylic Acid | 236 | 38.8 | 39.0 |
| Dupilumab | 671 | 14.5 | 14.5 |
| Hydroxyzine Hydrochloride | 22 | 13.4 | 13.4 |
| Hydroxyzine Hydrochloride Oral | 22 | 13.4 | 13.4 |
| Crisaborole | 12 | 10.0 | 10.0 |
| Brimonidine Tartrate | 22 | 9.9 | 9.9 |
| Mometasone | 21 | 9.1 | 9.2 |
| Nemolizumab-Ilto | 13 | 8.1 | 8.2 |
| Mupirocin | 13 | 7.7 | 7.7 |
| Mupirocin Calcium | 13 | 7.5 | 7.5 |
| Tretinoin | 6 | 5.9 | 5.9 |
| Epoprostenol | 8 | 4.9 | 4.9 |
| Azelastine | 10 | 4.4 | 4.4 |
| Fexofenadine Hydrochloride | 10 | 3.7 | 3.7 |
| Secukinumab | 70 | 3.5 | 3.5 |
| Mometasone Furoate And Formoterol Fumarate Dihydrate | 6 | 3.1 | 3.1 |
| Inclisiran | 3 | 3.0 | 3.0 |
| Cenegermin-Bkbj | 4 | 2.6 | 2.6 |
| Rimegepant Sulfate | 4 | 2.5 | 2.5 |
| Lifitegrast | 4 | 1.9 | 1.9 |
| Apremilast | 26 | 1.4 | 1.4 |
| Etonogestrel | 7 | 1.2 | 1.2 |