OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Bendamustine Hydrochloride

999 flagged reaction(s) · 35,055 total co-reports · max PRR 3,474.0
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Electrodesiccation 4 3,474.0 3,475.2 signal
2 B-cell Small Lymphocytic Lymphoma Recurrent 6 651.4 651.7 signal
3 Lymphoplasmacytoid Lymphoma/immunocytoma Recurrent 5 620.4 620.6 signal
4 Ascending Flaccid Paralysis 5 413.6 413.7 signal
5 Chondrosarcoma Metastatic 4 302.1 302.2 signal
6 Mantle Cell Lymphoma Recurrent 58 276.0 277.4 signal
7 Follicular Lymphoma Recurrent 9 252.1 252.3 signal
8 Infusion Site Phlebitis 27 235.7 236.2 signal
9 Follicular Lymphoma Refractory 7 233.8 234.0 signal
10 Exposure Via Contaminated Device 5 222.7 222.8 signal
11 Lymphoma Transformation 36 195.4 196.0 signal
12 Erythropoiesis Abnormal 25 157.3 157.7 signal
13 Coronavirus Pneumonia 13 155.7 155.9 signal
14 Apoptotic Colonopathy 6 139.0 139.0 signal
15 Paraneoplastic Pemphigus 8 117.8 117.8 signal
16 Tumour Obstruction 5 108.6 108.6 signal
17 Cytomegalovirus Enterocolitis 44 107.9 108.3 signal
18 Follicular Lymphoma 47 102.7 103.1 signal
19 Metastases To Retroperitoneum 9 98.3 98.4 signal
20 Leukaemia Cutis 8 95.8 95.9 signal
21 Injection Site Phlebitis 12 94.3 94.4 signal
22 Metastases To Muscle 9 93.1 93.1 signal
23 Cytomegalovirus Chorioretinitis 88 84.2 84.8 signal
24 Breakthrough Covid-19 10 79.0 79.0 signal
25 Vasogenic Cerebral Oedema 28 72.6 72.8 signal
26 Cd4 Lymphocytes Decreased 81 68.6 69.1 signal
27 Aspiration Bone Marrow Abnormal 5 67.3 67.4 signal
28 Diffuse Large B-cell Lymphoma Recurrent 77 65.5 65.9 signal
29 Humoral Immune Defect 13 63.8 63.9 signal
30 Mantle Cell Lymphoma 52 62.5 62.8 signal
31 Cytomegalovirus Test Positive 57 58.6 58.8 signal
32 Infusion Site Irritation 38 55.5 55.7 signal
33 Therapy Responder 15 55.2 55.3 signal
34 Polychromasia 9 54.1 54.1 signal
35 Alopecia Scarring 5 53.9 54.0 signal
36 Cytomegalovirus Gastroenteritis 6 51.9 51.9 signal
37 Cell-mediated Immune Deficiency 4 51.9 51.9 signal
38 Atypical Mycobacterial Pneumonia 4 51.5 51.5 signal
39 Nasal Abscess 6 47.6 47.6 signal
40 B-cell Lymphoma Recurrent 14 46.7 46.7 signal
41 Cytomegalovirus Hepatitis 9 46.0 46.0 signal
42 Chronic Lymphocytic Leukaemia Recurrent 17 44.3 44.3 signal
43 Bone Marrow Infiltration 9 42.0 42.1 signal
44 Encephalitis Cytomegalovirus 10 41.7 41.7 signal
45 Diffuse Large B-cell Lymphoma 174 41.1 41.7 signal
46 Post-acute Covid-19 Syndrome 28 40.8 40.9 signal
47 Chronic Lymphocytic Leukaemia 108 40.8 41.2 signal
48 Listeria Sepsis 6 40.6 40.6 signal
49 Extravasation 93 40.5 40.8 signal
50 Metastases To Bone Marrow 11 39.3 39.4 signal
51 Metastases To Spleen 9 38.9 38.9 signal
52 Hypertensive Cardiomyopathy 6 38.2 38.2 signal
53 Cerebral Aspergillosis 13 38.1 38.1 signal
54 Granuloma Skin 17 36.9 36.9 signal
55 Skin Neoplasm Excision 16 36.8 36.9 signal
56 Hypogammaglobulinaemia 127 35.6 35.9 signal
57 Urethral Obstruction 8 35.2 35.2 signal
58 Pneumonia Cytomegaloviral 36 33.6 33.7 signal
59 Lentigo Maligna 5 33.4 33.4 signal
60 Immunodeficiency Common Variable 9 33.1 33.1 signal
61 Ecthyma 7 31.1 31.1 signal
62 Cytomegalovirus Infection Reactivation 73 30.6 30.8 signal
63 Aplasia Pure Red Cell 58 30.2 30.3 signal
64 Tumour Lysis Syndrome 147 30.1 30.5 signal
65 Plasma Cell Leukaemia 10 29.9 29.9 signal
66 Clostridial Sepsis 4 29.8 29.8 signal
67 Infusion Site Reaction 48 29.6 29.7 signal
68 Cytomegalovirus Infection 271 29.2 29.8 signal
69 Gastrointestinal Fungal Infection 8 28.0 28.0 signal
70 Progressive Multifocal Leukoencephalopathy 128 27.7 28.0 signal
71 Human Polyomavirus Infection 8 27.5 27.5 signal
72 Pneumonia Escherichia 5 27.4 27.4 signal
73 Cytomegalovirus Viraemia 67 27.4 27.5 signal
74 Beta 2 Microglobulin Increased 4 27.4 27.4 signal
75 Coagulation Factor V Level Decreased 5 27.1 27.1 signal
76 Diffuse Large B-cell Lymphoma Refractory 14 26.9 26.9 signal
77 Lymphocyte Count Decreased 263 26.6 27.2 signal
78 Vein Discolouration 7 26.4 26.4 signal
79 Wound Necrosis 7 25.8 25.8 signal
80 Cytopenia 172 25.7 26.1 signal
81 Erythema Annulare 4 24.9 24.9 signal
82 Prescribed Underdose 278 24.9 25.5 signal
83 Congenital Aplasia 4 24.6 24.6 signal
84 Obliterative Bronchiolitis 18 24.2 24.3 signal
85 Neuroendocrine Carcinoma Of The Skin 13 23.8 23.8 signal
86 Cystitis Viral 5 23.4 23.4 signal
87 Klebsiella Test Positive 8 21.8 21.9 signal
88 Enterococcal Sepsis 10 21.8 21.8 signal
89 Covid-19 Pneumonia 145 21.7 22.0 signal
90 Oral Lichen Planus 6 21.7 21.7 signal
91 Sinus Polyp 7 21.6 21.6 signal
92 Procalcitonin Increased 14 21.6 21.6 signal
93 Anaemia Haemolytic Autoimmune 10 21.2 21.2 signal
94 Pneumonia Pseudomonal 18 21.1 21.1 signal
95 Tumour Flare 8 20.9 20.9 signal
96 Abdominal Lymphadenopathy 10 20.8 20.8 signal
97 Fungal Oesophagitis 8 20.6 20.6 signal
98 Autoimmune Haemolytic Anaemia 39 20.4 20.4 signal
99 Infusion Site Extravasation 71 20.3 20.4 signal
100 Blood Lactate Dehydrogenase Increased 182 20.3 20.6 signal
101 Blood Parathyroid Hormone Decreased 17 20.3 20.3 signal
102 Viral Haemorrhagic Cystitis 8 20.2 20.2 signal
103 Fungal Test Positive 4 20.1 20.1 signal
104 Scrotal Oedema 8 20.0 20.0 signal
105 Hepatitis Viral 9 20.0 20.0 signal
106 Plasma Cell Myeloma Refractory 14 19.2 19.2 signal
107 Opportunistic Infection 20 19.2 19.2 signal
108 Anisocytosis 7 19.2 19.2 signal
109 Coronavirus Infection 71 18.9 19.0 signal
110 Neutrophil Count Decreased 422 18.5 19.2 signal
111 B-cell Lymphoma 34 17.7 17.7 signal
112 Non-hodgkin's Lymphoma 13 17.4 17.4 signal
113 Hepatitis B Reactivation 31 17.3 17.4 signal
114 Infection In An Immunocompromised Host 7 17.3 17.3 signal
115 B-lymphocyte Count Decreased 13 17.1 17.2 signal
116 Cytomegalovirus Colitis 21 16.5 16.5 signal
117 Organising Pneumonia 45 16.3 16.3 signal
118 Neoplasm Skin 14 16.0 16.0 signal
119 Candida Sepsis 8 15.8 15.8 signal
120 Pulmonary Mycosis 7 15.7 15.7 signal
121 Biopsy Bone Marrow Abnormal 4 15.5 15.5 signal
122 Immune Thrombocytopenic Purpura 25 15.5 15.5 signal
123 Febrile Infection 10 15.4 15.4 signal
124 Pneumococcal Infection 5 15.1 15.1 signal
125 Cryoglobulinaemia 6 15.1 15.1 signal
126 Phlebitis 43 14.9 14.9 signal
127 Vaccination Failure 14 14.9 14.9 signal
128 Oral Fungal Infection 23 14.9 14.9 signal
129 Malignant Pleural Effusion 14 14.8 14.8 signal
130 Panniculitis 20 14.7 14.7 signal
131 Hepatitis E 13 14.7 14.7 signal
132 Varicella Zoster Virus Infection 17 14.6 14.6 signal
133 Myelodysplastic Syndrome 119 14.6 14.7 signal
134 Blood Immunoglobulin G Decreased 20 14.6 14.6 signal
135 Jc Virus Infection 13 14.4 14.5 signal
136 Febrile Neutropenia 535 14.3 15.0 signal
137 Aplasia 16 14.2 14.2 signal
138 Myelosuppression 272 14.2 14.5 signal
139 Extranodal Marginal Zone B-cell Lymphoma (malt Type) 4 14.1 14.1 signal
140 Granulocyte Count Decreased 14 13.9 14.0 signal
141 Demyelinating Polyneuropathy 8 13.8 13.8 signal
142 Infusion Site Induration 11 13.7 13.7 signal
143 Mucosal Erosion 7 13.7 13.7 signal
144 Herpes Zoster Disseminated 6 13.4 13.4 signal
145 Dysplasia 9 13.4 13.4 signal
146 Vulval Disorder 5 13.4 13.4 signal
147 Secondary Immunodeficiency 9 13.4 13.4 signal
148 Chronic Myelomonocytic Leukaemia 5 13.3 13.3 signal
149 Cerebral Toxoplasmosis 7 13.3 13.3 signal
150 Second Primary Malignancy 61 13.0 13.1 signal
151 Neutropenic Infection 7 12.8 12.8 signal
152 Pneumocystis Jirovecii Pneumonia 71 12.6 12.7 signal
153 Prinzmetal Angina 7 12.5 12.5 signal
154 Orthostatic Intolerance 5 12.4 12.4 signal
155 Infusion Site Discolouration 6 12.3 12.4 signal
156 Pancytopenia 386 12.3 12.7 signal
157 Abdominal Sepsis 6 12.2 12.2 signal
158 Metastasis 49 12.1 12.1 signal
159 Cryptococcosis 11 12.1 12.1 signal
160 Blister Rupture 5 12.0 12.1 signal
161 Urinary Tract Infection Bacterial 17 12.0 12.0 signal
162 Blood Bilirubin Decreased 4 11.4 11.4 signal
163 Vasculitic Rash 5 11.4 11.4 signal
164 Therapy Partial Responder 97 11.4 11.5 signal
165 Neutropenic Sepsis 46 11.4 11.4 signal
166 Haematotoxicity 59 11.3 11.3 signal
167 Vascular Pain 6 11.2 11.2 signal
168 Lymphopenia 89 11.2 11.3 signal
169 Pneumocystis Jiroveci Pneumonia 14 11.0 11.0 signal
170 Infusion Site Pain 79 11.0 11.0 signal
171 Rheumatoid Nodule 17 10.8 10.8 signal
172 Acute Myeloid Leukaemia 94 10.7 10.8 signal
173 Infusion Site Oedema 5 10.7 10.7 signal
174 Bacteraemia 71 10.7 10.7 signal
175 Jc Polyomavirus Test Positive 7 10.5 10.5 signal
176 Haemolytic Anaemia 53 10.4 10.5 signal
177 Enterovirus Infection 5 10.4 10.4 signal
178 Neurological Symptom 33 10.3 10.3 signal
179 Pseudomembranous Colitis 13 10.3 10.3 signal
180 Serum Sickness 16 10.2 10.2 signal
181 Lymphoma 89 10.2 10.2 signal
182 Bronchopulmonary Aspergillosis 44 10.1 10.1 signal
183 Chylothorax 4 9.9 9.9 signal
184 Venoocclusive Disease 14 9.9 9.9 signal
185 Bone Marrow Failure 113 9.8 9.9 signal
186 Fear Of Injection 38 9.6 9.7 signal
187 Adenocarcinoma Gastric 5 9.6 9.6 signal
188 Enterococcal Infection 26 9.5 9.5 signal
189 Aspergillosis 7 9.3 9.4 signal
190 Debridement 4 9.2 9.2 signal
191 Nephrogenic Diabetes Insipidus 6 9.2 9.2 signal
192 Staphylococcal Bacteraemia 22 9.0 9.0 signal
193 Rash Morbilliform 14 8.9 8.9 signal
194 Giant Cell Arteritis 4 8.8 8.8 signal
195 Hepatitis B 30 8.8 8.8 signal
196 Dermatitis Exfoliative Generalised 17 8.7 8.8 signal
197 Rash Maculo-papular 109 8.7 8.8 signal
198 Infusion Site Discomfort 5 8.7 8.7 signal
199 Venoocclusive Liver Disease 24 8.6 8.6 signal
200 Post Herpetic Neuralgia 7 8.6 8.6 signal
201 Disease Progression 572 8.6 9.0 signal
202 End Stage Renal Disease 88 8.4 8.5 signal
203 Febrile Bone Marrow Aplasia 20 8.4 8.5 signal
204 Squamous Cell Carcinoma 45 8.4 8.5 signal
205 Acute Febrile Neutrophilic Dermatosis 11 8.4 8.4 signal
206 Neoplasm Recurrence 16 8.3 8.3 signal
207 Streptococcal Bacteraemia 5 8.2 8.2 signal
208 Epstein-barr Viraemia 5 8.1 8.1 signal
209 Bacterial Sepsis 15 8.1 8.1 signal
210 Hyperleukocytosis 4 8.1 8.1 signal
211 Cytokine Release Syndrome 87 8.1 8.1 signal
212 Infusion Site Swelling 28 8.0 8.1 signal
213 Listeriosis 5 8.0 8.0 signal
214 Acarodermatitis 5 8.0 8.0 signal
215 Squamous Cell Carcinoma Of Skin 27 7.9 7.9 signal
216 Systemic Candida 11 7.9 7.9 signal
217 Klebsiella Sepsis 5 7.8 7.8 signal
218 Pneumonia Fungal 17 7.7 7.8 signal
219 Hypercalcaemia 54 7.7 7.8 signal
220 Lobar Pneumonia 8 7.5 7.5 signal
221 Gastrointestinal Toxicity 20 7.5 7.5 signal
222 H1n1 Influenza 6 7.5 7.5 signal
223 Myositis 38 7.5 7.5 signal
224 Adenovirus Infection 12 7.4 7.4 signal
225 Pneumonia Influenzal 5 7.4 7.4 signal
226 Hydronephrosis 31 7.3 7.4 signal
227 Upper Respiratory Tract Inflammation 5 7.3 7.3 signal
228 Platelet Count Decreased 438 7.3 7.5 signal
229 Red Blood Cell Count Abnormal 6 7.2 7.3 signal
230 Administration Site Extravasation 4 7.2 7.2 signal
231 Breath Sounds Abnormal 20 7.2 7.2 signal
232 Skin Necrosis 21 7.1 7.1 signal
233 Paresis 9 7.1 7.1 signal
234 Adenocarcinoma 9 7.1 7.1 signal
235 Klebsiella Infection 20 7.0 7.0 signal
236 Infusion Related Reaction 262 7.0 7.1 signal
237 Systemic Inflammatory Response Syndrome 15 7.0 7.0 signal
238 Peripheral Sensory Neuropathy 23 7.0 7.0 signal
239 Basal Cell Carcinoma 61 6.9 6.9 signal
240 Hyperuricaemia 16 6.9 6.9 signal
241 Red Cell Distribution Width Increased 16 6.8 6.8 signal
242 Immune Thrombocytopenia 17 6.7 6.7 signal
243 Erysipelas 19 6.6 6.7 signal
244 Immune Effector Cell-associated Neurotoxicity Syndrome 21 6.6 6.6 signal
245 Adenocarcinoma Of Colon 7 6.6 6.6 signal
246 Plasmacytoma 7 6.6 6.6 signal
247 Malignant Neoplasm Progression 378 6.6 6.7 signal
248 Aspergillus Infection 24 6.5 6.5 signal
249 Neutropenia 501 6.5 6.8 signal
250 Enterocolitis 21 6.5 6.5 signal
251 Lymphadenopathy 130 6.5 6.5 signal
252 Pseudomonas Infection 31 6.5 6.5 signal
253 Stevens-johnson Syndrome 80 6.3 6.4 signal
254 Peripheral Motor Neuropathy 5 6.3 6.3 signal
255 Escherichia Urinary Tract Infection 15 6.2 6.2 signal
256 Clostridial Infection 12 6.2 6.2 signal
257 Ileus 43 6.2 6.2 signal
258 Acute Sinusitis 6 6.2 6.2 signal
259 Diffuse Alveolar Damage 4 6.1 6.1 signal
260 Suspected Off Label Use 6 6.1 6.1 signal
261 Hyperthermia 26 6.1 6.1 signal
262 Spinal Cord Injury 6 6.1 6.1 signal
263 Multiple Myeloma 16 6.0 6.0 signal
264 Pneumonia Pneumococcal 5 6.0 6.0 signal
265 Drug Tolerance 17 5.9 5.9 signal
266 Splenomegaly 39 5.9 5.9 signal
267 Guillain-barre Syndrome 16 5.9 5.9 signal
268 Thrombocytopenia 367 5.8 6.0 signal
269 Lymphocytosis 7 5.8 5.8 signal
270 Infusion Site Erythema 27 5.8 5.8 signal
271 Aplastic Anaemia 17 5.7 5.7 signal
272 White Blood Cell Count Decreased 351 5.7 5.9 signal
273 Cystitis Haemorrhagic 13 5.7 5.7 signal
274 Haemolysis 25 5.7 5.7 signal
275 Staphylococcal Sepsis 16 5.7 5.7 signal
276 Eastern Cooperative Oncology Group Performance Status Worsened 4 5.7 5.7 signal
277 Eosinophilia 56 5.7 5.7 signal
278 Neutrophil Count Abnormal 9 5.6 5.6 signal
279 Disseminated Intravascular Coagulation 45 5.6 5.6 signal
280 Drug Eruption 56 5.6 5.6 signal
281 Pneumonia Bacterial 29 5.6 5.6 signal
282 Osteosclerosis 5 5.6 5.6 signal
283 Epstein-barr Virus Infection Reactivation 4 5.6 5.6 signal
284 Rhinovirus Infection 12 5.6 5.6 signal
285 Blood Uric Acid Increased 18 5.5 5.5 signal
286 Idiopathic Thrombocytopenic Purpura 5 5.5 5.5 signal
287 Septic Shock 134 5.5 5.5 signal
288 Vasculitis 36 5.5 5.5 signal
289 Toxic Skin Eruption 31 5.4 5.4 signal
290 Lymphocyte Count Increased 10 5.4 5.4 signal
291 Plasma Cell Myeloma Recurrent 10 5.4 5.4 signal
292 Agranulocytosis 56 5.3 5.4 signal
293 Escherichia Bacteraemia 7 5.3 5.3 signal
294 Gastroenteritis Norovirus 4 5.3 5.3 signal
295 Retinitis 5 5.3 5.3 signal
296 Dermatitis Exfoliative 15 5.2 5.2 signal
297 Device Related Sepsis 6 5.2 5.2 signal
298 Rheumatoid Factor Positive 17 5.2 5.2 signal
299 Type Iv Hypersensitivity Reaction 8 5.2 5.2 signal
300 Blood Count Abnormal 45 5.2 5.2 signal
301 Central Nervous System Lymphoma 4 5.1 5.1 signal
302 Meningitis Cryptococcal 5 5.1 5.1 signal
303 Atypical Mycobacterial Infection 4 5.1 5.1 signal
304 Skin Toxicity 16 5.1 5.1 signal
305 Pseudomonal Sepsis 5 5.0 5.0 signal
306 Thrombophlebitis 10 5.0 5.0 signal
307 Pneumonia Viral 9 5.0 5.0 signal
308 Oesophageal Candidiasis 11 4.9 4.9 signal
309 Vein Disorder 14 4.9 4.9 signal
310 Brain Abscess 7 4.9 4.9 signal
311 Immunosuppression 24 4.9 4.9 signal
312 Nocardiosis 7 4.8 4.8 signal
313 Lung Opacity 7 4.8 4.8 signal
314 Bacterial Test Positive 6 4.8 4.8 signal
315 C-reactive Protein Abnormal 17 4.7 4.7 signal
316 Plasma Cell Myeloma 103 4.6 4.7 signal
317 Lichen Planus 6 4.6 4.6 signal
318 Urosepsis 24 4.6 4.6 signal
319 Candida Infection 43 4.5 4.6 signal
320 Blood Phosphorus Increased 7 4.5 4.5 signal
321 Non-small Cell Lung Cancer 12 4.5 4.5 signal
322 Femoral Neck Fracture 13 4.5 4.5 signal
323 Mucosal Inflammation 66 4.5 4.5 signal
324 Respiratory Symptom 7 4.4 4.4 signal
325 Haemophagocytic Lymphohistiocytosis 18 4.4 4.4 signal
326 Lung Consolidation 7 4.4 4.4 signal
327 Pyrexia 861 4.4 4.7 signal
328 Atelectasis 24 4.4 4.4 signal
329 Neoplasm Progression 85 4.3 4.3 signal
330 Escherichia Sepsis 7 4.3 4.3 signal
331 Diverticular Perforation 5 4.3 4.3 signal
332 Anaemia Macrocytic 5 4.2 4.2 signal
333 Aortic Valve Incompetence 10 4.1 4.1 signal
334 Nephropathy Toxic 26 4.1 4.1 signal
335 Covid-19 411 4.1 4.2 signal
336 Oral Disorder 17 4.1 4.1 signal
337 Glomerular Filtration Rate Decreased 28 4.1 4.1 signal
338 Sepsis 255 4.0 4.1 signal
339 Clostridium Difficile Colitis 24 4.0 4.0 signal
340 Epstein-barr Virus Associated Lymphoproliferative Disorder 4 4.0 4.0 signal
341 Inflammatory Marker Increased 11 4.0 4.0 signal
342 Hepatic Function Abnormal 83 4.0 4.0 signal
343 Metastases To Meninges 5 3.9 3.9 signal
344 Hypoalbuminaemia 17 3.9 3.9 signal
345 Skin Reaction 31 3.9 3.9 signal
346 Skin Erosion 7 3.9 3.9 signal
347 Ventricular Hypokinesia 7 3.8 3.8 signal
348 Herpes Zoster 125 3.8 3.9 signal
349 Gastrointestinal Perforation 9 3.8 3.8 signal
350 Herpes Simplex 14 3.8 3.8 signal
351 Pemphigoid 16 3.8 3.8 signal
352 Oral Candidiasis 28 3.8 3.8 signal
353 Lung Infiltration 19 3.8 3.8 signal
354 Otitis Media 7 3.7 3.7 signal
355 Failure To Thrive 11 3.7 3.7 signal
356 Pulmonary Tuberculosis 9 3.7 3.7 signal
357 Pleural Effusion 127 3.7 3.7 signal
358 Anaemia 395 3.7 3.7 signal
359 Neuropathy Peripheral 194 3.6 3.7 signal
360 Hypogeusia 4 3.6 3.6 signal
361 Hyperbilirubinaemia 21 3.6 3.6 signal
362 Acute Coronary Syndrome 17 3.6 3.6 signal
363 C-reactive Protein Increased 74 3.6 3.6 signal
364 Encephalitis 14 3.6 3.6 signal
365 Atypical Pneumonia 6 3.5 3.6 signal
366 Aortic Stenosis 7 3.5 3.5 signal
367 Leukopenia 100 3.5 3.6 signal
368 Hypoaesthesia Oral 30 3.5 3.5 signal
369 Histiocytosis Haematophagic 6 3.5 3.5 signal
370 Jaundice Cholestatic 7 3.5 3.5 signal
371 Recurrent Cancer 8 3.5 3.5 signal
372 Inguinal Hernia 12 3.5 3.5 signal
373 Cachexia 10 3.4 3.4 signal
374 Generalised Oedema 24 3.4 3.4 signal
375 Capillary Leak Syndrome 4 3.4 3.4 signal
376 Interstitial Lung Disease 94 3.4 3.5 signal
377 Mucormycosis 5 3.4 3.4 signal
378 Performance Status Decreased 9 3.4 3.4 signal
379 Hypertransaminasaemia 13 3.4 3.4 signal
380 Psychomotor Skills Impaired 5 3.4 3.4 signal
381 Immune System Disorder 25 3.4 3.4 signal
382 Hyperlactacidaemia 5 3.3 3.3 signal
383 Atrial Flutter 15 3.3 3.3 signal
384 Leukoencephalopathy 7 3.3 3.3 signal
385 Faecaloma 10 3.2 3.2 signal
386 Infection Susceptibility Increased 4 3.2 3.2 signal
387 Immunosuppressant Drug Level Increased 6 3.2 3.2 signal
388 Device Related Infection 28 3.2 3.2 signal
389 Left Ventricular Dysfunction 12 3.2 3.2 signal
390 Embolism 15 3.2 3.2 signal
391 Post Transplant Lymphoproliferative Disorder 9 3.2 3.2 signal
392 Multiple Organ Dysfunction Syndrome 50 3.2 3.2 signal
393 Drug Resistance 46 3.2 3.2 signal
394 Dermatitis 37 3.1 3.2 signal
395 Cytolytic Hepatitis 6 3.1 3.1 signal
396 Lung Infection 28 3.1 3.1 signal
397 Polyneuropathy 21 3.1 3.1 signal
398 Thrombotic Microangiopathy 17 3.1 3.1 signal
399 Blood Disorder 14 3.1 3.1 signal
400 Generalised Erythema 10 3.1 3.1 signal
401 Chills 203 3.0 3.1 signal
402 Bronchopneumonia 6 3.0 3.0 signal
403 Pulmonary Fibrosis 33 3.0 3.0 signal
404 Product Use In Unapproved Indication 416 3.0 3.1 signal
405 Pneumonitis 46 3.0 3.0 signal
406 Hepatitis Fulminant 5 3.0 3.0 signal
407 Hypovolaemic Shock 8 3.0 3.0 signal
408 Aortic Dissection 7 3.0 3.0 signal
409 Aspartate Aminotransferase Increased 89 3.0 3.0 signal
410 Atrial Fibrillation 163 2.9 3.0 signal
411 Nonspecific Reaction 9 2.9 2.9 signal
412 Bacterial Infection 31 2.9 2.9 signal
413 Bone Marrow Disorder 5 2.9 2.9 signal
414 Cardiac Failure Acute 11 2.9 2.9 signal
415 Blood Culture Positive 5 2.9 2.9 signal
416 Meningitis 11 2.9 2.9 signal
417 Amylase Increased 6 2.9 2.9 signal
418 Glomerulonephritis 4 2.9 2.9 no signal
419 Thrombophlebitis Superficial 5 2.9 2.9 signal
420 Red Blood Cell Sedimentation Rate Increased 18 2.9 2.9 signal
421 Blood Pressure Decreased 107 2.8 2.9 signal
422 Drug Reaction With Eosinophilia And Systemic Symptoms 41 2.8 2.8 signal
423 Rash Generalised 42 2.8 2.8 signal
424 Angiopathy 9 2.8 2.8 signal
425 Troponin Increased 12 2.8 2.8 signal
426 Red Blood Cell Count Decreased 45 2.8 2.8 signal
427 Haemoglobin Abnormal 10 2.8 2.8 signal
428 Neoplasm 18 2.8 2.8 signal
429 Hypovolaemia 9 2.7 2.7 signal
430 Infection 221 2.7 2.7 signal
431 Blood Lactic Acid Increased 8 2.7 2.7 signal
432 Deafness Neurosensory 5 2.7 2.7 no signal
433 Odynophagia 9 2.7 2.7 signal
434 Ulcer 24 2.7 2.7 signal
435 Abdominal Mass 4 2.6 2.6 no signal
436 Bk Virus Infection 5 2.6 2.6 no signal
437 Anal Abscess 8 2.6 2.6 signal
438 Creatinine Renal Clearance Decreased 6 2.6 2.6 signal
439 Cardiomyopathy 22 2.6 2.6 signal
440 Gastrointestinal Injury 4 2.6 2.6 no signal
441 Arthritis Bacterial 6 2.6 2.6 signal
442 Escherichia Infection 12 2.6 2.6 signal
443 Alanine Aminotransferase Increased 90 2.6 2.6 signal
444 Toxic Epidermal Necrolysis 22 2.6 2.6 signal
445 Haematocrit Decreased 29 2.6 2.6 signal
446 Acute Graft Versus Host Disease In Skin 4 2.6 2.6 no signal
447 Hyperpyrexia 6 2.6 2.6 signal
448 Pneumonia 466 2.5 2.6 signal
449 Respiratory Failure 104 2.5 2.5 signal
450 Pulmonary Toxicity 10 2.5 2.5 signal
451 Acute Pulmonary Oedema 8 2.5 2.5 signal
452 Enteritis 9 2.5 2.5 signal
453 Drug Ineffective For Unapproved Indication 78 2.5 2.5 signal
454 Gamma-glutamyltransferase Increased 31 2.5 2.5 signal
455 Hypoxia 49 2.5 2.5 signal
456 Erythema Multiforme 13 2.5 2.5 signal
457 Granulocytopenia 8 2.5 2.5 signal
458 Graft Versus Host Disease 10 2.4 2.4 signal
459 Metabolic Disorder 8 2.4 2.4 signal
460 Refusal Of Treatment By Patient 9 2.4 2.4 signal
461 Chronic Graft Versus Host Disease 5 2.4 2.4 no signal
462 Rash Pruritic 74 2.4 2.4 signal
463 Oesophagitis 15 2.4 2.4 signal
464 Bronchiectasis 9 2.4 2.4 signal
465 Stomatitis 81 2.4 2.4 signal
466 Platelet Count Abnormal 8 2.3 2.3 signal
467 General Physical Condition Abnormal 9 2.3 2.3 signal
468 Subdural Haematoma 19 2.3 2.3 signal
469 Pathogen Resistance 12 2.3 2.3 signal
470 Embolism Venous 4 2.3 2.3 no signal
471 Hypokalaemia 60 2.3 2.3 signal
472 Off Label Use 1,133 2.3 2.4 signal
473 Duodenitis 4 2.3 2.3 no signal
474 Nodule 17 2.3 2.3 signal
475 Immunodeficiency 19 2.3 2.3 signal
476 Hepatitis 33 2.3 2.3 signal
477 Oliguria 8 2.3 2.3 signal
478 Epstein-barr Virus Infection 8 2.3 2.3 signal
479 Rash 557 2.3 2.3 signal
480 Blood Test Abnormal 18 2.3 2.3 signal
481 Therapy Non-responder 57 2.3 2.3 signal
482 Anuria 11 2.2 2.2 signal
483 Staphylococcal Infection 42 2.2 2.2 signal
484 Ventricular Tachycardia 21 2.2 2.2 signal
485 Liver Disorder 56 2.2 2.2 signal
486 Malnutrition 14 2.2 2.2 signal
487 Ascites 37 2.2 2.2 signal
488 Streptococcal Infection 7 2.2 2.2 no signal
489 Supraventricular Tachycardia 12 2.2 2.2 signal
490 Acute Respiratory Distress Syndrome 22 2.2 2.2 signal
491 Organ Failure 5 2.2 2.2 no signal
492 Renal Tubular Necrosis 12 2.2 2.2 signal
493 Herpes Virus Infection 7 2.1 2.1 no signal
494 Neurotoxicity 21 2.1 2.1 signal
495 Hypotonia 12 2.1 2.1 signal
496 Colitis 45 2.1 2.1 signal
497 Colitis Ischaemic 8 2.1 2.1 no signal
498 Acute Kidney Injury 180 2.1 2.1 signal
499 Tachypnoea 16 2.1 2.1 signal
500 Aphthous Ulcer 9 2.1 2.1 no signal
501 Gout 21 2.1 2.1 signal
502 Intestinal Perforation 13 2.0 2.0 signal
503 Granuloma 4 2.0 2.0 no signal
504 Respiratory Tract Infection 30 2.0 2.0 signal
505 Hypomagnesaemia 16 2.0 2.0 signal
506 Acute Respiratory Failure 22 2.0 2.0 signal
507 Hepatic Cytolysis 14 2.0 2.0 signal
508 Viral Infection 38 2.0 2.0 signal
509 Polyarthritis 6 2.0 2.0 no signal
510 Respiratory Distress 31 2.0 2.0 no signal
511 Cutaneous Vasculitis 4 2.0 2.0 no signal
512 Meningitis Aseptic 5 2.0 2.0 no signal
513 Rash Papular 25 2.0 2.0 no signal
514 Rash Erythematous 52 2.0 2.0 no signal
515 Bone Lesion 4 2.0 2.0 no signal
516 Haemoglobin Decreased 114 2.0 2.0 no signal
517 Vascular Device Infection 5 2.0 2.0 no signal
518 Eosinophil Count Increased 9 1.9 1.9 no signal
519 Acute Graft Versus Host Disease 5 1.9 1.9 no signal
520 Chronic Sinusitis 4 1.9 1.9 no signal
521 Renal Impairment 89 1.9 1.9 no signal
522 Myocarditis 12 1.9 1.9 no signal
523 Leukocytosis 19 1.9 1.9 no signal
524 Cardiac Tamponade 5 1.8 1.8 no signal
525 Sars-cov-2 Test Positive 14 1.8 1.8 no signal
526 Cholestasis 20 1.8 1.8 no signal
527 Metastases To Lymph Nodes 7 1.8 1.8 no signal
528 Subcutaneous Abscess 5 1.8 1.8 no signal
529 Blood Creatinine Increased 68 1.8 1.8 no signal
530 Sudden Death 11 1.8 1.8 no signal
531 Ejection Fraction Decreased 16 1.8 1.8 no signal
532 Body Temperature Increased 21 1.8 1.8 no signal
533 Decreased Immune Responsiveness 10 1.8 1.8 no signal
534 Hypotension 204 1.8 1.8 no signal
535 Cardiotoxicity 9 1.8 1.8 no signal
536 General Physical Health Deterioration 116 1.8 1.8 no signal
537 Face Oedema 17 1.8 1.8 no signal
538 Pneumonia Aspiration 25 1.8 1.8 no signal
539 Pericardial Effusion 23 1.8 1.8 no signal
540 Azotaemia 4 1.8 1.8 no signal
541 Blood Bilirubin Increased 27 1.8 1.8 no signal
542 Fungal Infection 33 1.7 1.7 no signal
543 Product Use Issue 185 1.7 1.8 no signal
544 Candidiasis 4 1.7 1.7 no signal
545 Hepatic Encephalopathy 9 1.7 1.7 no signal
546 Tubulointerstitial Nephritis 18 1.7 1.7 no signal
547 Disorientation 38 1.7 1.7 no signal
548 Intentional Product Use Issue 84 1.7 1.7 no signal
549 Skin Lesion 26 1.7 1.7 no signal
550 Hypocalcaemia 18 1.7 1.7 no signal
551 Metastases To Lung 11 1.7 1.7 no signal
552 Incorrect Drug Administration Rate 4 1.7 1.7 no signal
553 Synovitis 17 1.7 1.7 no signal
554 White Blood Cell Count Abnormal 6 1.7 1.7 no signal
555 Cardiac Failure Chronic 4 1.7 1.7 no signal
556 Metastases To Central Nervous System 12 1.7 1.7 no signal
557 Renal Failure Acute 40 1.6 1.6 no signal
558 Anaphylactic Reaction 51 1.6 1.6 no signal
559 Myopathy 8 1.6 1.6 no signal
560 Dehydration 123 1.6 1.6 no signal
561 Ankylosing Spondylitis 12 1.6 1.6 no signal
562 Adrenal Insufficiency 11 1.6 1.6 no signal
563 Sinus Tachycardia 13 1.6 1.6 no signal
564 Multi-organ Failure 16 1.6 1.6 no signal
565 White Blood Cell Count Increased 35 1.6 1.6 no signal
566 Purpura 8 1.6 1.6 no signal
567 Small Intestinal Obstruction 11 1.6 1.6 no signal
568 Necrosis 5 1.6 1.6 no signal
569 Liver Function Test Abnormal 26 1.6 1.6 no signal
570 Rebound Effect 10 1.6 1.6 no signal
571 Peroneal Nerve Palsy 5 1.5 1.5 no signal
572 Clostridium Difficile Infection 19 1.5 1.5 no signal
573 Pulmonary Mass 13 1.5 1.5 no signal
574 Skin Disorder 29 1.5 1.5 no signal
575 Conjunctivitis 16 1.5 1.5 no signal
576 Electrolyte Imbalance 10 1.5 1.5 no signal
577 Petechiae 9 1.5 1.5 no signal
578 Hepatic Cirrhosis 16 1.5 1.5 no signal
579 Metastases To Liver 15 1.5 1.5 no signal
580 Jaundice 23 1.5 1.5 no signal
581 Pulmonary Embolism 81 1.5 1.5 no signal
582 Blood Alkaline Phosphatase Increased 21 1.5 1.5 no signal
583 Hypersensitivity 156 1.5 1.5 no signal
584 Cholecystitis 10 1.5 1.5 no signal
585 Disease Recurrence 40 1.5 1.5 no signal
586 Spinal Compression Fracture 7 1.5 1.5 no signal
587 Hepatic Failure 25 1.5 1.5 no signal
588 Cardiac Failure 66 1.4 1.4 no signal
589 Decreased Appetite 190 1.4 1.5 no signal
590 Pneumothorax 13 1.4 1.4 no signal
591 Anaphylactic Shock 21 1.4 1.4 no signal
592 Encephalopathy 20 1.4 1.4 no signal
593 Pyelonephritis 7 1.4 1.4 no signal
594 Hepatotoxicity 18 1.4 1.4 no signal
595 Fluid Intake Reduced 4 1.4 1.4 no signal
596 Acute Hepatic Failure 11 1.4 1.4 no signal
597 Skin Infection 9 1.4 1.4 no signal
598 Hypernatraemia 4 1.4 1.4 no signal
599 Orthostatic Hypotension 14 1.4 1.4 no signal
600 Injection Site Extravasation 10 1.4 1.4 no signal
601 Therapeutic Response Decreased 48 1.4 1.4 no signal
602 Cellulitis 40 1.4 1.4 no signal
603 Hypophagia 20 1.4 1.4 no signal
604 Endocarditis 4 1.4 1.4 no signal
605 Neutrophil Count Increased 8 1.4 1.4 no signal
606 Cardiac Disorder 73 1.4 1.4 no signal
607 Acute Myocardial Infarction 23 1.4 1.4 no signal
608 Cerebral Ischaemia 4 1.4 1.4 no signal
609 Ventricular Extrasystoles 8 1.4 1.4 no signal
610 Circulatory Collapse 13 1.3 1.3 no signal
611 Oedema 41 1.3 1.3 no signal
612 Treatment Failure 62 1.3 1.3 no signal
613 Gastroenteritis 11 1.3 1.3 no signal
614 Delirium 26 1.3 1.3 no signal
615 Malignant Melanoma 10 1.3 1.3 no signal
616 Tachycardia 66 1.3 1.3 no signal
617 Skin Ulcer 19 1.3 1.3 no signal
618 Hiccups 6 1.3 1.3 no signal
619 Drug Level Below Therapeutic 4 1.3 1.3 no signal
620 Ischaemic Stroke 13 1.3 1.3 no signal
621 Erythema 149 1.3 1.3 no signal
622 Renal Failure 97 1.3 1.3 no signal
623 Hyperkalaemia 25 1.3 1.3 no signal
624 Lung Disorder 35 1.3 1.3 no signal
625 Bronchitis 53 1.3 1.3 no signal
626 Blindness 29 1.3 1.3 no signal
627 Psychotic Disorder 21 1.3 1.3 no signal
628 Mitral Valve Incompetence 8 1.2 1.2 no signal
629 Haemodialysis 6 1.2 1.2 no signal
630 Skin Swelling 6 1.2 1.2 no signal
631 Inflammation 36 1.2 1.2 no signal
632 Altered State Of Consciousness 15 1.2 1.2 no signal
633 Full Blood Count Decreased 14 1.2 1.2 no signal
634 Respiratory Syncytial Virus Infection 6 1.2 1.2 no signal
635 Pulmonary Oedema 31 1.2 1.2 no signal
636 Hyperventilation 4 1.2 1.2 no signal
637 Rash Macular 24 1.2 1.2 no signal
638 Cystitis 22 1.2 1.2 no signal
639 Rash Pustular 5 1.2 1.2 no signal
640 Hypophosphataemia 5 1.2 1.2 no signal
641 Drug Effect Incomplete 25 1.2 1.2 no signal
642 Ataxia 8 1.2 1.2 no signal
643 Tenderness 7 1.2 1.2 no signal
644 Colon Cancer 10 1.2 1.2 no signal
645 Hepatitis Cholestatic 4 1.2 1.2 no signal
646 Lipase Increased 5 1.2 1.2 no signal
647 Blood Urea Increased 11 1.2 1.2 no signal
648 Chronic Obstructive Pulmonary Disease 34 1.1 1.1 no signal
649 No Therapeutic Response 8 1.1 1.1 no signal
650 Hemiparesis 11 1.1 1.1 no signal
651 Dermatitis Allergic 8 1.1 1.1 no signal
652 Flank Pain 6 1.1 1.1 no signal
653 Tricuspid Valve Incompetence 5 1.1 1.1 no signal
654 Urinary Retention 21 1.1 1.1 no signal
655 Transaminases Increased 14 1.1 1.1 no signal
656 Ventricular Fibrillation 7 1.1 1.1 no signal
657 Pulmonary Hypertension 13 1.1 1.1 no signal
658 Liver Injury 15 1.1 1.1 no signal
659 Prescribed Overdose 12 1.1 1.1 no signal
660 Sinus Bradycardia 6 1.1 1.1 no signal
661 Syncope 62 1.1 1.1 no signal
662 Diverticulitis 17 1.1 1.1 no signal
663 Intestinal Obstruction 23 1.1 1.1 no signal
664 Cerebral Infarction 15 1.1 1.1 no signal
665 Haematuria 21 1.1 1.1 no signal
666 Mental Status Changes 17 1.1 1.1 no signal
667 Polyuria 5 1.1 1.1 no signal
668 Cholelithiasis 20 1.1 1.1 no signal
669 Flushing 62 1.1 1.1 no signal
670 Nervous System Disorder 19 1.1 1.1 no signal
671 Deep Vein Thrombosis 39 1.1 1.1 no signal
672 Emphysema 6 1.0 1.0 no signal
673 Upper Gastrointestinal Haemorrhage 10 1.0 1.0 no signal
674 Melaena 13 1.0 1.0 no signal
675 Subarachnoid Haemorrhage 6 1.0 1.0 no signal
676 Drug Level Decreased 6 1.0 1.0 no signal
677 Cardiac Arrest 48 1.0 1.0 no signal
678 Asthenia 216 1.0 1.0 no signal
679 Urine Output Decreased 5 1.0 1.0 no signal
680 Shock 13 1.0 1.0 no signal
681 Blindness Unilateral 8 1.0 1.0 no signal
682 Arrhythmia 27 1.0 1.0 no signal
683 Oral Herpes 11 1.0 1.0 no signal
684 Abscess 9 1.0 1.0 no signal
685 Pemphigus 7 1.0 1.0 no signal
686 Blood Pressure Systolic Increased 11 1.0 1.0 no signal
687 Decreased Activity 6 1.0 1.0 no signal
688 Gastrointestinal Infection 5 1.0 1.0 no signal
689 Dermatitis Bullous 4 1.0 1.0 no signal
690 Hyperglycaemia 20 1.0 1.0 no signal
691 Drug Intolerance 52 1.0 1.0 no signal
692 Appendicitis 5 0.9 0.9 no signal
693 Haemorrhage Intracranial 8 0.9 0.9 no signal
694 Cerebral Haemorrhage 19 0.9 0.9 no signal
695 Leukaemia 5 0.9 0.9 no signal
696 Pancreatitis 28 0.9 0.9 no signal
697 Abdominal Pain 123 0.9 0.9 no signal
698 Diarrhoea 337 0.9 0.9 no signal
699 Constipation 113 0.9 0.9 no signal
700 Acute Generalised Exanthematous Pustulosis 4 0.9 0.9 no signal
701 Atrioventricular Block 4 0.9 0.9 no signal
702 Hepatic Enzyme Increased 35 0.9 0.9 no signal
703 Vitreous Floaters 5 0.9 0.9 no signal
704 Therapeutic Product Effect Incomplete 36 0.9 0.9 no signal
705 Feeling Cold 14 0.9 0.9 no signal
706 Taste Disorder 10 0.9 0.9 no signal
707 Motor Dysfunction 5 0.9 0.9 no signal
708 Pancreatitis Acute 11 0.9 0.9 no signal
709 Death 424 0.9 0.9 no signal
710 Hepatocellular Injury 7 0.9 0.9 no signal
711 Eyelid Ptosis 5 0.9 0.9 no signal
712 Cardiogenic Shock 7 0.9 0.9 no signal
713 Tooth Abscess 5 0.9 0.9 no signal
714 Cardiomegaly 6 0.9 0.9 no signal
715 Influenza 54 0.9 0.8 no signal
716 Product Preparation Error 10 0.9 0.9 no signal
717 Peritonitis 10 0.9 0.9 no signal
718 Tooth Extraction 6 0.8 0.8 no signal
719 Dyspnoea Exertional 18 0.8 0.8 no signal
720 Dysarthria 18 0.8 0.8 no signal
721 Vomiting 224 0.8 0.8 no signal
722 Mouth Ulceration 10 0.8 0.8 no signal
723 Laboratory Test Abnormal 14 0.8 0.8 no signal
724 Full Blood Count Abnormal 5 0.8 0.8 no signal
725 Oedema Peripheral 58 0.8 0.8 no signal
726 Therapeutic Product Effect Decreased 21 0.8 0.8 no signal
727 Electrocardiogram Qt Prolonged 17 0.8 0.8 no signal
728 Nausea 372 0.8 0.8 no signal
729 Renal Disorder 22 0.8 0.8 no signal
730 Blister 26 0.8 0.8 no signal
731 Blood Magnesium Decreased 4 0.8 0.8 no signal
732 Confusional State 75 0.8 0.8 no signal
733 Loss Of Personal Independence In Daily Activities 22 0.8 0.8 no signal
734 Haematoma 12 0.8 0.8 no signal
735 Deafness 12 0.8 0.8 no signal
736 Burning Sensation 32 0.8 0.8 no signal
737 Upper Respiratory Tract Infection 21 0.8 0.8 no signal
738 Groin Pain 4 0.8 0.8 no signal
739 Local Swelling 8 0.8 0.8 no signal
740 Cough 126 0.8 0.8 no signal
741 Thirst 8 0.8 0.8 no signal
742 Urinary Tract Infection 76 0.8 0.8 no signal
743 Alopecia 86 0.8 0.8 no signal
744 Myocardial Ischaemia 5 0.8 0.8 no signal
745 Dry Eye 21 0.8 0.8 no signal
746 Urticaria 72 0.8 0.8 no signal
747 Toxicity To Various Agents 72 0.8 0.8 no signal
748 Mass 6 0.8 0.8 no signal
749 Hyponatraemia 24 0.8 0.8 no signal
750 Nephropathy 4 0.8 0.8 no signal
751 Blood Urine Present 8 0.7 0.7 no signal
752 Dyspnoea 237 0.7 0.7 no signal
753 Weight Decreased 116 0.7 0.7 no signal
754 Skin Exfoliation 34 0.7 0.7 no signal
755 Dysuria 15 0.7 0.7 no signal
756 Urinary Incontinence 12 0.7 0.7 no signal
757 Respiratory Disorder 12 0.7 0.7 no signal
758 Blood Potassium Decreased 12 0.7 0.7 no signal
759 Fatigue 309 0.7 0.7 no signal
760 Pruritus 150 0.7 0.7 no signal
761 Hypothermia 4 0.7 0.7 no signal
762 Abdominal Pain Lower 10 0.7 0.7 no signal
763 Incorrect Product Administration Duration 8 0.7 0.7 no signal
764 Inappropriate Antidiuretic Hormone Secretion 4 0.7 0.7 no signal
765 Bone Pain 23 0.7 0.7 no signal
766 Drug Hypersensitivity 75 0.7 0.7 no signal
767 Cardio-respiratory Arrest 16 0.7 0.7 no signal
768 Pulmonary Congestion 5 0.7 0.7 no signal
769 Incontinence 4 0.7 0.7 no signal
770 Oxygen Saturation Decreased 21 0.7 0.7 no signal
771 Lower Respiratory Tract Infection 17 0.7 0.7 no signal
772 Breast Cancer Metastatic 4 0.7 0.7 no signal
773 Night Sweats 12 0.7 0.7 no signal
774 Proteinuria 7 0.7 0.7 no signal
775 Fracture 7 0.7 0.7 no signal
776 Aspiration 4 0.7 0.6 no signal
777 Gastric Ulcer 7 0.6 0.6 no signal
778 Generalised Tonic-clonic Seizure 6 0.6 0.6 no signal
779 Renal Injury 11 0.6 0.6 no signal
780 Abasia 9 0.6 0.6 no signal
781 Hypertensive Crisis 4 0.6 0.6 no signal
782 Haemorrhoids 7 0.6 0.6 no signal
783 Kidney Infection 7 0.6 0.6 no signal
784 Wrong Technique In Drug Usage Process 13 0.6 0.6 no signal
785 Spinal Fracture 7 0.6 0.6 no signal
786 Gastrointestinal Disorder 31 0.6 0.6 no signal
787 Back Pain 81 0.6 0.6 no signal
788 Paralysis 5 0.6 0.6 no signal
789 Metabolic Acidosis 11 0.6 0.6 no signal
790 Thrombosis 28 0.6 0.6 no signal
791 Skin Haemorrhage 5 0.6 0.6 no signal
792 Haemorrhage 36 0.6 0.6 no signal
793 Apathy 5 0.6 0.6 no signal
794 Drug Effective For Unapproved Indication 10 0.6 0.6 no signal
795 Spinal Pain 4 0.6 0.6 no signal
796 Arthropathy 19 0.6 0.6 no signal
797 Drug Ineffective 448 0.6 0.6 no signal
798 Flatulence 19 0.6 0.6 no signal
799 Heart Rate Increased 33 0.6 0.6 no signal
800 Contraindicated Product Administered 10 0.6 0.6 no signal
801 Presyncope 8 0.6 0.6 no signal
802 Lethargy 19 0.6 0.6 no signal
803 Aphasia 10 0.6 0.6 no signal
804 Depressed Level Of Consciousness 13 0.6 0.6 no signal
805 Suicide Attempt 20 0.6 0.6 no signal
806 Ill-defined Disorder 20 0.6 0.6 no signal
807 Eating Disorder 7 0.6 0.6 no signal
808 Dementia 9 0.6 0.6 no signal
809 Haemoptysis 9 0.6 0.6 no signal
810 Personality Change 3 0.6 0.6 no signal
811 Abnormal Weight Gain 4 0.6 0.6 no signal
812 Eczema 16 0.6 0.6 no signal
813 Skin Fissures 6 0.6 0.6 no signal
814 Cyanosis 5 0.6 0.6 no signal
815 Injection Site Irritation 4 0.6 0.6 no signal
816 Angina Pectoris 9 0.5 0.5 no signal
817 Gastrointestinal Haemorrhage 26 0.5 0.5 no signal
818 Cardiac Failure Congestive 25 0.5 0.5 no signal
819 Blood Potassium Increased 5 0.5 0.5 no signal
820 Tremor 51 0.5 0.5 no signal
821 Dysphagia 29 0.5 0.5 no signal
822 Anorexia 4 0.5 0.5 no signal
823 Chest Discomfort 31 0.5 0.5 no signal
824 Hypertension 64 0.5 0.5 no signal
825 Myocardial Infarction 53 0.5 0.5 no signal
826 Pericarditis 5 0.5 0.5 no signal
827 Upper Limb Fracture 6 0.5 0.5 no signal
828 Chest Pain 55 0.5 0.5 no signal
829 Malaise 129 0.5 0.5 no signal
830 Gingival Bleeding 4 0.5 0.5 no signal
831 Arthritis 23 0.5 0.5 no signal
832 Respiratory Arrest 8 0.5 0.5 no signal
833 Diabetes Mellitus 22 0.5 0.5 no signal
834 Bradycardia 15 0.5 0.5 no signal
835 Retching 6 0.5 0.5 no signal
836 Hyperhidrosis 36 0.5 0.5 no signal
837 Movement Disorder 9 0.5 0.5 no signal
838 Productive Cough 13 0.5 0.5 no signal
839 Pulmonary Arterial Hypertension 4 0.5 0.5 no signal
840 Musculoskeletal Stiffness 24 0.5 0.5 no signal
841 Gastric Cancer 7 0.5 0.5 no signal
842 Sinusitis 28 0.5 0.5 no signal
843 Diplopia 7 0.5 0.5 no signal
844 Visual Acuity Reduced 9 0.5 0.5 no signal
845 Condition Aggravated 81 0.5 0.5 no signal
846 Dysgeusia 20 0.5 0.5 no signal
847 Lung Neoplasm Malignant 11 0.5 0.5 no signal
848 Blood Sodium Decreased 5 0.5 0.5 no signal
849 Blood Pressure Increased 40 0.5 0.5 no signal
850 Paraesthesia 41 0.5 0.5 no signal
851 Gastric Haemorrhage 3 0.5 0.5 no signal
852 Pallor 7 0.5 0.5 no signal
853 Swollen Tongue 8 0.5 0.5 no signal
854 Peripheral Swelling 39 0.4 0.4 no signal
855 Lactic Acidosis 8 0.4 0.4 no signal
856 Hepatic Cancer 6 0.4 0.4 no signal
857 Myalgia 42 0.4 0.4 no signal
858 Muscular Weakness 28 0.4 0.4 no signal
859 Swelling Face 16 0.4 0.4 no signal
860 Blood Creatine Phosphokinase Increased 7 0.4 0.4 no signal
861 Cognitive Disorder 11 0.4 0.4 no signal
862 Fluid Retention 12 0.4 0.4 no signal
863 Liver Function Test Increased 5 0.4 0.4 no signal
864 Skin Cancer 5 0.4 0.4 no signal
865 Pruritus Generalised 5 0.4 0.4 no signal
866 Head Discomfort 4 0.4 0.4 no signal
867 Oropharyngeal Pain 21 0.4 0.4 no signal
868 Cold Sweat 4 0.4 0.4 no signal
869 Angioedema 10 0.4 0.4 no signal
870 Ear Infection 6 0.4 0.4 no signal
871 Fall 75 0.4 0.4 no signal
872 Unevaluable Event 17 0.4 0.4 no signal
873 Joint Swelling 27 0.4 0.4 no signal
874 Pain Of Skin 6 0.4 0.4 no signal
875 Throat Tightness 6 0.4 0.4 no signal
876 Head Injury 7 0.4 0.4 no signal
877 Loss Of Consciousness 28 0.4 0.4 no signal
878 Skin Discolouration 10 0.4 0.4 no signal
879 Central Nervous System Lesion 3 0.4 0.4 no signal
880 Prostatic Specific Antigen Increased 3 0.4 0.4 no signal
881 Eye Swelling 8 0.4 0.4 no signal
882 Drug Interaction 34 0.4 0.4 no signal
883 Palmar-plantar Erythrodysaesthesia Syndrome 5 0.4 0.4 no signal
884 Nasopharyngitis 39 0.4 0.4 no signal
885 Hypoaesthesia 31 0.4 0.4 no signal
886 Transient Ischaemic Attack 7 0.4 0.4 no signal
887 Neuralgia 5 0.4 0.4 no signal
888 Wheezing 12 0.4 0.4 no signal
889 Colitis Ulcerative 9 0.4 0.4 no signal
890 Osteonecrosis Of Jaw 5 0.4 0.4 no signal
891 Activities Of Daily Living Impaired 4 0.4 0.4 no signal
892 Epilepsy 6 0.3 0.3 no signal
893 Pain In Extremity 58 0.3 0.3 no signal
894 Feeling Hot 12 0.3 0.3 no signal
895 Unresponsive To Stimuli 5 0.3 0.3 no signal
896 Limb Discomfort 6 0.3 0.3 no signal
897 Drug Dispensing Error 3 0.3 0.3 no signal
898 Swelling 18 0.3 0.3 no signal
899 Abdominal Distension 20 0.3 0.3 no signal
900 Rhabdomyolysis 8 0.3 0.3 no signal
901 Abdominal Discomfort 32 0.3 0.3 no signal
902 Gastritis 5 0.3 0.3 no signal
903 Palpitations 22 0.3 0.3 no signal
904 Insomnia 50 0.3 0.3 no signal
905 Rheumatoid Arthritis 21 0.3 0.3 no signal
906 Impaired Healing 6 0.3 0.3 no signal
907 Haematochezia 10 0.3 0.3 no signal
908 Discomfort 11 0.3 0.3 no signal
909 Dizziness 90 0.3 0.3 no signal
910 Lip Swelling 6 0.3 0.3 no signal
911 Abnormal Dreams 5 0.3 0.3 no signal
912 Circumstance Or Information Capable Of Leading To Medication Error 6 0.3 0.3 no signal
913 Contusion 17 0.3 0.3 no signal
914 Headache 110 0.3 0.3 no signal
915 Incorrect Drug Administration Duration 5 0.3 0.3 no signal
916 Pain 107 0.3 0.3 no signal
917 Epistaxis 13 0.3 0.3 no signal
918 Dry Mouth 14 0.3 0.3 no signal
919 Speech Disorder 9 0.3 0.3 no signal
920 Weight Increased 38 0.3 0.3 no signal
921 Heart Rate Decreased 6 0.3 0.3 no signal
922 Chronic Kidney Disease 13 0.3 0.3 no signal
923 Underdose 12 0.3 0.3 no signal
924 Dyspepsia 16 0.3 0.3 no signal
925 Drug-induced Liver Injury 5 0.3 0.3 no signal
926 Depression 37 0.3 0.3 no signal
927 Arthralgia 67 0.3 0.3 no signal
928 Femur Fracture 5 0.3 0.3 no signal
929 Hot Flush 12 0.3 0.3 no signal
930 Hypothyroidism 5 0.3 0.3 no signal
931 Therapy Cessation 8 0.3 0.3 no signal
932 Cardiovascular Disorder 4 0.3 0.3 no signal
933 Bladder Cancer 9 0.3 0.3 no signal
934 Type 2 Diabetes Mellitus 5 0.3 0.3 no signal
935 Disturbance In Attention 8 0.3 0.3 no signal
936 Pollakiuria 6 0.3 0.3 no signal
937 Abdominal Pain Upper 29 0.2 0.2 no signal
938 Rhinorrhoea 9 0.2 0.2 no signal
939 Dysstasia 4 0.2 0.2 no signal
940 Muscle Spasms 25 0.2 0.2 no signal
941 Injection Site Mass 5 0.2 0.2 no signal
942 Prostate Cancer 11 0.2 0.2 no signal
943 Throat Irritation 6 0.2 0.2 no signal
944 Musculoskeletal Pain 7 0.2 0.2 no signal
945 Vertigo 8 0.2 0.2 no signal
946 Nephrolithiasis 6 0.2 0.2 no signal
947 Injection Site Reaction 9 0.2 0.2 no signal
948 Coronary Artery Disease 4 0.2 0.2 no signal
949 Tinnitus 6 0.2 0.2 no signal
950 Coma 6 0.2 0.2 no signal
951 Neck Pain 7 0.2 0.2 no signal
952 Hypoglycaemia 6 0.2 0.2 no signal
953 Amnesia 8 0.2 0.2 no signal
954 Agitation 9 0.2 0.2 no signal
955 Eye Disorder 4 0.2 0.2 no signal
956 Seizure 14 0.2 0.2 no signal
957 Injection Site Pain 37 0.2 0.2 no signal
958 Dry Skin 16 0.2 0.2 no signal
959 Neoplasm Malignant 8 0.2 0.2 no signal
960 Gait Disturbance 23 0.2 0.2 no signal
961 Dysphonia 7 0.2 0.2 no signal
962 Nasal Congestion 7 0.2 0.2 no signal
963 Adverse Event 11 0.2 0.2 no signal
964 Cataract 7 0.2 0.2 no signal
965 Osteoarthritis 5 0.2 0.2 no signal
966 Gastrooesophageal Reflux Disease 9 0.2 0.2 no signal
967 Cerebrovascular Accident 19 0.2 0.2 no signal
968 Blood Glucose Increased 21 0.2 0.2 no signal
969 Visual Impairment 13 0.2 0.2 no signal
970 Convulsion 6 0.2 0.2 no signal
971 Therapy Interrupted 7 0.2 0.2 no signal
972 Abnormal Behaviour 4 0.2 0.2 no signal
973 Mobility Decreased 7 0.2 0.2 no signal
974 Hallucination 7 0.2 0.2 no signal
975 Acne 7 0.2 0.2 no signal
976 No Adverse Event 16 0.2 0.2 no signal
977 Eye Irritation 5 0.2 0.2 no signal
978 Feeling Abnormal 21 0.2 0.2 no signal
979 Blood Glucose Decreased 4 0.1 0.1 no signal
980 Renal Cancer 4 0.1 0.1 no signal
981 Balance Disorder 7 0.1 0.1 no signal
982 Accidental Exposure To Product 8 0.1 0.1 no signal
983 Memory Impairment 11 0.1 0.1 no signal
984 Intentional Overdose 5 0.1 0.1 no signal
985 Somnolence 15 0.1 0.1 no signal
986 Anxiety 21 0.1 0.1 no signal
987 Adverse Drug Reaction 6 0.1 0.1 no signal
988 Hospitalisation 10 0.1 0.1 no signal
989 Overdose 11 0.1 0.1 no signal
990 Illness 5 0.1 0.1 no signal
991 Injection Site Erythema 6 0.1 0.1 no signal
992 Asthma 5 0.1 0.1 no signal
993 Incorrect Dose Administered 10 0.1 0.1 no signal
994 Vision Blurred 6 0.1 0.1 no signal
995 Breast Cancer 4 0.1 0.1 no signal
996 Drug Dose Omission 6 0.1 0.1 no signal
997 Wrong Technique In Product Usage Process 7 0.1 0.1 no signal
998 Inappropriate Schedule Of Product Administration 4 0.0 0.0 no signal
999 Product Dose Omission Issue 5 0.0 0.0 no signal