Reaction

Hypogammaglobulinaemia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,328 reports · 236 co-occurring drugs

As of the last recalculation, Hypogammaglobulinaemia appears in 6,328 FAERS reports alongside 236 co-occurring drug terms. The strongest observed disproportionality signal is FLUDARABINE PHOSPHATE (PRR 75.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Fludarabine Phosphate	790	75.4	76.9
Axicabtagene Ciloleucel	161	55.0	55.9
Obinutuzumab	238	49.4	50.1
Rituximab	2,077	47.6	48.1
Bendamustine Hcl	183	39.9	40.4
Polatuzumab Vedotin	107	36.7	37.1
Bendamustine Hydrochloride	127	35.6	35.9
Cyclophosphamide Injection, Solution	1,437	34.2	34.5
Cyclophosphamide	1,437	34.2	34.5
Cyclophosphamide For Injection	1,437	34.2	34.5
Daratumumab	317	27.4	27.6
Thiotepa	74	25.8	26.0
Blinatumomab	70	22.3	22.4
Sirolimus	89	22.0	22.2
Melphalan	147	21.7	21.9
Valganciclovir Hydrochloride Powder,	77	21.0	21.1
Melphalan Hydrochloride	154	20.7	20.8
Anti-Thymocyte Globulin (Rabbit)	49	20.1	20.2
Carfilzomib	165	19.7	19.8
Ganciclovir Sodium	61	19.1	19.2
Ganciclovir	59	19.1	19.2
Mycophenolate Mofetil	690	18.6	18.7
Mycophenolate Mofetil Hydrochloride	690	18.6	18.7
Cytarabine	301	17.3	17.3
Busulfan	81	17.1	17.2
Doxorubicin	427	16.8	16.9
Valganciclovir	91	16.1	16.2
Valganciclovir Hydrochloride	91	16.1	16.2
Mycophenilic Acid	95	15.3	15.4
Ifosfamide	96	14.9	15.0
Doxorubicin Hydrochloride	138	14.2	14.2
Tacrolimus Ointment 0.1%	497	14.2	14.2
Tacrolimus Extended-Release Capsules	497	14.1	14.2
Human Immunoglobulin G	87	14.0	14.1
Posaconazole Delayed-Release	44	13.3	13.3
Etoposide	281	13.1	13.2
Prednisolone	633	12.7	12.8
Prednisolone Oral	633	12.7	12.8
Prednisolone Oral Solution	633	12.7	12.8
Tacrolimus	546	12.5	12.5
Alemtuzumab	71	12.2	12.2
Vincristine Sulfate	107	12.2	12.2
Cyclosporine	380	11.9	11.9
Methylprednisolone	462	11.8	11.8
Micafungin Sodium	28	10.9	10.9
Mycophenolic Acid	104	10.8	10.9
Ocrelizumab	195	10.6	10.7
Mesna	27	10.6	10.6
Basiliximab	37	10.4	10.4
Mesna Injection	26	10.4	10.4
Posaconazole	50	10.2	10.2
Bortezomib	247	9.4	9.4
Filgrastim	106	9.4	9.4
Ibrutinib	215	9.0	9.0
Ofatumumab	90	9.0	9.0
Dexamethasone Sodium Phosphate	27	8.8	8.8
Amphotericin B	32	8.4	8.5
Azathioprine	215	8.3	8.3
Dexamethasone 1.5 Mg	649	8.0	8.0
Dexamethasone	649	7.9	7.9
Valacyclovir	98	7.8	7.9
Venetoclax	136	7.4	7.4
Itraconazole	25	7.1	7.1
Pegaspargase	26	7.0	7.0
Budesonide	123	7.0	7.0
Lamotirigine	149	7.0	7.0
Lamotrigine Extended-Release	149	7.0	7.0
Lamotrigine Chewable Dispersible	149	7.0	7.0
Atovaquone	17	7.0	7.0
Acyclovir	232	6.9	6.9
Methylprednisolone Sodium Succinate	94	6.7	6.8
Prednisone	870	6.4	6.4
Carbamazepine	128	6.4	6.4
Hydroxychloroquine	138	6.2	6.2
Cefepime Hydrochloride	30	6.1	6.2
Thalidomide	68	6.1	6.2
Cisplatin	139	6.0	6.0
Voriconazole Injection	38	5.8	5.8
Anakinra	29	5.8	5.8
Valacyclovir Hydrochloride	121	5.7	5.7
Sulfamethoxazole And Trimethoprim	144	5.7	5.7
Remdesivir	23	5.7	5.7
Ciclesonide	23	5.6	5.6
Mercaptopurine	29	5.5	5.5
Cefepime	22	5.1	5.1
Oseltamivir	12	5.0	5.0
Azithromycin	60	4.9	4.9
Lamotrigine	192	4.9	4.9
Voriconazole	45	4.9	4.9
Tocilizumab	166	4.9	4.9
Azithromycin Monohydrate	61	4.9	4.9
Meropenem	45	4.6	4.6
Selinexor	12	4.6	4.6
Hydrocortisone Sodium Succinate	13	4.6	4.6
Ixazomib	38	4.4	4.4
Telmisartan	23	4.3	4.3
Fluconazole	89	4.2	4.2
Azithromycin Dihydrate	73	4.1	4.1
Granisetron Hydrochloride	13	4.1	4.1
Daspone	12	4.1	4.1
Dapsone Gel, 5%	12	4.1	4.1
Nystatin Ointment	32	4.0	4.0
Nystatin Cream	32	4.0	4.0
Desloratadine	13	4.0	4.0
Ampicillin	10	4.0	4.0
Ampicillin Sodium	10	4.0	4.0
Trimethoprim	14	3.9	3.9
Methotrexate	470	3.9	3.9
Linezolid	35	3.9	3.9
Nystatin	32	3.9	3.9
Methotrexate Sodium	526	3.8	3.8
Pomalidomide	116	3.8	3.8
Belimumab	36	3.8	3.8
Piperacillin Sodium,Tazobactam Sodium	30	3.7	3.7
Theophylline	13	3.7	3.7
Theophylline Anhydrous	14	3.7	3.7
Dapsone	12	3.7	3.7
Oxcarbazepine	36	3.7	3.7
Phenytoin	23	3.6	3.6
Magnesium Sulfate In Water For	14	3.6	3.6
Febuxostat Tablets 40 Mg	11	3.6	3.6
Febuxostat Tablets 80 Mg	11	3.6	3.6
Magnesium Sulfate Heptahydrate	14	3.5	3.5
Magnesium Sulfate	14	3.5	3.5
Risedronate Sodium	33	3.5	3.5
Romiplostim	16	3.5	3.5
Ruxolitinib	75	3.5	3.5
Entecavir	12	3.4	3.4
Allopurinol	154	3.3	3.3
Acalabrutinib	12	3.3	3.3
Piperacillin Sodium And Tazobactam Sodium	19	3.2	3.2
Acetaminophen Tablet Extended Release	240	3.2	3.2
Pain Reliever	240	3.2	3.2
Acetaminophen 500Mg	240	3.2	3.2
Levetiracetam In Sodium Chloride	72	3.1	3.1
Levetiracetam Oral	72	3.1	3.1
Levetiracetam Injection	72	3.1	3.1
Zoledronic Acid	37	3.0	3.0
Adalimumab-Fkjp	42	3.0	3.0
Erythromycin	17	3.0	3.0
Febuxostat	15	2.9	3.0
Adalimumab-Aaty	42	2.9	2.9
Anti-Itch	59	2.9	2.9
Anti-Pruritic	59	2.9	2.9
Antipruritic (Anti-Itch)	59	2.9	2.9
Cool Relief Gel With Aloe	59	2.9	2.9
Drs. Hydrocortisone	59	2.9	2.9
Hydrocortisone Continuous Spray	59	2.9	2.9
Hydrocortisone Spray	59	2.9	2.9
Anti-Itch Cream	59	2.9	2.9
Hydrocortisone Lotion	59	2.9	2.9
Hydrocortisone Cream 1%	59	2.9	2.9
Hydrocortisone Cream 1/2%	59	2.9	2.9
Hydrocortisone 1%	59	2.9	2.9
Hydrocortisone Cream	59	2.9	2.9
Zonisamide	13	2.9	2.9
Montelukast	73	2.9	2.9
Diphenhydramine	55	2.9	2.9
Prednisolone Acetate	9	2.9	2.9
Fexofenadine Hcl	8	2.8	2.9
Fondaparinux Sodium	7	2.8	2.8
Magnesium Oxide	36	2.8	2.8
Epoetin Alfa	10	2.8	2.8
Ciprofolxacin	60	2.8	2.8
Ciprofloxacin Tablets	60	2.8	2.8
Clindamycin Phosphate	28	2.8	2.8
Hydroxyzine Hydrochloride	11	2.8	2.8
Hydroxyzine Hydrochloride Oral	11	2.8	2.8
Canakinumab	9	2.7	2.7
Baricitinib	8	2.7	2.7
Adalimumab-Adaz	43	2.7	2.7
Zinc	20	2.7	2.7
Amoxicillin And Clavulanate Potassium	22	2.7	2.7
Zinc Chloride	20	2.7	2.7
Oxybutynin Chloride	7	2.6	2.6
Ceftriaxone	26	2.6	2.6
Vancomycin Hydrochloride	52	2.6	2.6
Leflunomide	82	2.6	2.6
Paroxetine Hydrochloride Hemihydrate	26	2.6	2.6
Erythropoietin	16	2.6	2.6
Insulin Glargine-Yfgn	17	2.6	2.6
Cefazolin	7	2.5	2.5
Paroxetine	26	2.5	2.5
Vancomycin	44	2.5	2.5
Clozapine	95	2.5	2.5
Tofacitinib Citrate	10	2.5	2.5
Temozolomide	16	2.5	2.5
Ceftriaxone Sodium	29	2.5	2.5
Cefazolin Sodium	9	2.5	2.5
Dronabinol	6	2.5	2.5
Sulfasalazine	58	2.5	2.5
Montelukast Sodium	90	2.5	2.5
Gemcitabine	29	2.4	2.4
Imatinib	13	2.4	2.4
Fosaprepitant Dimeglumine	10	2.4	2.4
Gemcitabine Hydrochloride	38	2.4	2.4
Rifaximin	15	2.4	2.4
Lenalidomide	289	2.3	2.3
Clobazam	17	2.3	2.3
Carboplatin	87	2.3	2.3
Terbinafine Hydrochloride	6	2.2	2.2
Levetiracetam	89	2.2	2.2
Darbepoetin Alfa	35	2.1	2.1
Haloperidol Lactate	16	2.1	2.1
Amikacin	11	2.1	2.1
Ursodiol	14	2.1	2.1
Piperacillin And Tazobactam	8	2.1	2.1
Haloperidol	15	2.0	2.0
Omalizumab	52	2.0	2.0
Azacitidine For	11	2.0	2.0
Brentuximab Vedotin	6	1.9	1.9
Oseltamivir Phosphate	14	1.9	1.9
Granisetron	6	1.9	1.9
Dasatinib	21	1.9	1.9
Rifampin	8	1.8	1.8
Carboxymethylcellulose Sodium	5	1.8	1.8
Eltrombopag Olamine	12	1.7	1.7
Cladribine	5	1.7	1.7
Abatacept	71	1.7	1.7
Eculizumab	27	1.6	1.6
Cenobamate	4	1.6	1.6
Brivaracetam	4	1.5	1.5
Ribavirin	28	1.4	1.4
Fexofenadine Hydrochloride	9	1.4	1.4
Dapagliflozin	13	1.4	1.4
Pertuzumab	11	1.3	1.3
Azacitidine	12	1.3	1.3
Teriflunomide	18	1.3	1.3
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	16	1.3	1.3
Tapentadol Hydrochloride	12	1.2	1.2
Travoprost	3	1.1	1.1
Bosutinib	3	1.1	1.1
Sofosbuvir	6	1.0	1.0
Palivizumab	3	0.6	0.6
Nirmatrelvir And Ritonavir	10	0.6	0.6
Pegfilgrastim	18	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.