Reaction

Angle Closure Glaucoma reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,528 reports · 46 co-occurring drugs

As of the last recalculation, Angle Closure Glaucoma appears in 2,528 FAERS reports alongside 46 co-occurring drug terms. The strongest observed disproportionality signal is TOPIRAMATE (PRR 68.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Topiramate	597	68.7	69.2
Atropine	20	20.0	20.1
Timolol	27	18.6	18.6
Atropine Sulfate	23	17.7	17.7
Posaconazole Delayed-Release	20	15.1	15.1
Brimonidine Tartrate	32	15.0	15.0
Brinzolamide	15	14.3	14.3
Dorzolamide Hydrochloride And Timolol Maleate	12	12.6	12.6
Chlorthalidone	17	12.1	12.1
Prednisolone Acetate	15	12.0	12.0
Timolol Maleate	14	11.7	11.7
Norepinephrine	14	10.8	10.9
Tobramycin Sulfate	16	10.7	10.7
Posaconazole	20	10.2	10.2
Umeclidinium	11	10.2	10.2
Sevoflurane	10	9.9	10.0
Tobramycin Solution	14	9.6	9.7
Latanoprost	55	9.2	9.2
Sumatriptan Succinate	27	8.9	8.9
Labetalol	14	8.7	8.7
Ranibizumab	26	8.1	8.1
Dexamethasone Sodium Phosphate	10	8.1	8.1
Norepinephrine Bitartrate	14	8.0	8.1
Zonisamide	14	7.8	7.8
Sumatriptan	35	7.7	7.7
Amoxicillin And Clavulanate Potassium	23	7.0	7.0
Citalopram Hydrobromide	88	7.0	7.0
Remdesivir	11	6.8	6.8
Naltrexone Hydrochloride And Bupropion Hydrochloride	7	6.8	6.8
Primidone	8	6.5	6.5
Rocuronium Bromide	9	6.3	6.3
Aflibercept	23	6.1	6.1
Escitslopram	40	5.7	5.7
Asenapine Maleate	6	5.7	5.7
Bimatoprost	19	5.5	5.5
Memantine	9	5.4	5.4
Memantine Hydrochloride	9	5.4	5.4
Midazolam	16	5.3	5.3
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	21	4.9	4.9
Tobramycin	14	4.8	4.8
Fesoterodine Fumarate	6	4.6	4.6
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	22	4.4	4.4
Vortioxetine	9	4.4	4.4
Daratumumab	20	4.1	4.1
Travoprost	4	3.8	3.8
Desvenlafaxine Succinate	10	3.1	3.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.