OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Cenobamate

806 flagged reaction(s) · 27,203 total co-reports · max PRR 787.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Epilepsy Surgery 6 787.4 787.9 signal
2 Opsoclonus 3 440.0 440.2 signal
3 Polyneuropathy Idiopathic Progressive 7 290.9 291.1 signal
4 Pneumonitis Aspiration 32 265.1 266.1 signal
5 Product Regimen Confusion 4 249.3 249.4 signal
6 Seizure Cluster 63 214.9 216.5 signal
7 Vagal Nerve Stimulator Implantation 23 212.4 213.0 signal
8 Aura 112 162.0 164.2 signal
9 Electroencephalogram 3 141.1 141.2 signal
10 Cortical Dysplasia 3 133.6 133.6 signal
11 Increased Need For Sleep 9 108.4 108.5 signal
12 Drug Titration Error 101 102.7 103.9 signal
13 Postictal Psychosis 6 101.8 101.8 signal
14 Neuroprosthesis Implantation 5 100.5 100.6 signal
15 Drug Metabolite Level High 3 95.9 95.9 signal
16 Atonic Seizures 27 88.6 88.9 signal
17 Focal Dyscognitive Seizures 38 86.9 87.3 signal
18 Deja Vu 9 86.3 86.4 signal
19 Change In Seizure Presentation 19 75.3 75.5 signal
20 Sudden Unexplained Death In Epilepsy 15 72.1 72.2 signal
21 Partial Seizures 126 63.3 64.2 signal
22 Multiple-drug Resistance 72 60.2 60.7 signal
23 Petit Mal Epilepsy 114 57.9 58.7 signal
24 Seizure 2,450 55.1 77.8 signal
25 Tonic Convulsion 29 53.4 53.5 signal
26 Drug Titration 3 53.0 53.1 signal
27 Electrocardiogram Qt Shortened 5 42.8 42.9 signal
28 Postictal Paralysis 4 42.4 42.5 signal
29 Brain Operation 33 37.5 37.7 signal
30 Mitral Valve Thickening 4 36.9 37.0 signal
31 Increased Dose Administered 4 36.3 36.3 signal
32 Generalised Tonic-clonic Seizure 213 33.3 34.2 signal
33 Psychogenic Seizure 12 33.3 33.3 signal
34 Antimicrobial Susceptibility Test Resistant 4 32.8 32.8 signal
35 Partial Seizures With Secondary Generalisation 6 32.7 32.8 signal
36 Myoclonic Epilepsy 18 31.3 31.3 signal
37 Product Packaging Difficult To Open 29 30.0 30.1 signal
38 Epileptic Aura 3 29.7 29.7 signal
39 Slow Speech 25 26.6 26.7 signal
40 Craniotomy 4 24.9 24.9 signal
41 Postictal State 10 24.7 24.7 signal
42 Skull Fracture 15 23.5 23.5 signal
43 Gastrostomy 14 23.2 23.3 signal
44 Repetitive Speech 5 22.7 22.8 signal
45 Thrombocytosis 32 22.3 22.4 signal
46 Patient Elopement 3 22.3 22.3 signal
47 Head Banging 5 22.1 22.2 signal
48 Simple Partial Seizures 7 21.8 21.9 signal
49 Clonic Convulsion 6 20.9 20.9 signal
50 Feeling Drunk 60 20.5 20.6 signal
51 Occipital Neuralgia 4 18.1 18.1 signal
52 Rapid Eye Movements Sleep Abnormal 3 17.9 17.9 signal
53 Behaviour Disorder 37 17.7 17.8 signal
54 Drug Dose Titration Not Performed 12 17.7 17.7 signal
55 Paradoxical Drug Reaction 25 17.3 17.4 signal
56 Temporal Lobe Epilepsy 3 17.3 17.3 signal
57 Coma Scale Abnormal 19 16.9 16.9 signal
58 Ataxia 78 16.6 16.8 signal
59 Product Dose Omission Issue 1,837 16.4 20.8 signal
60 Diplopia 163 16.0 16.3 signal
61 Hypermagnesaemia 4 15.9 15.9 signal
62 Idiosyncratic Drug Reaction 6 15.5 15.5 signal
63 Loss Of Employment 18 15.0 15.0 signal
64 Hypersomnia 169 15.0 15.3 signal
65 Staring 14 14.8 14.8 signal
66 Febrile Convulsion 7 14.6 14.6 signal
67 Status Epilepticus 65 14.6 14.7 signal
68 Peripheral Sensorimotor Neuropathy 7 14.4 14.4 signal
69 Anticonvulsant Drug Level Increased 9 14.1 14.1 signal
70 Macroglossia 3 13.9 13.9 signal
71 Electroencephalogram Abnormal 17 13.7 13.7 signal
72 Oedematous Pancreatitis 3 13.6 13.7 signal
73 Lip Injury 7 13.6 13.6 signal
74 Sleep Deficit 11 13.5 13.5 signal
75 Tracheitis 4 13.4 13.4 signal
76 Gastrointestinal Tube Insertion 13 13.2 13.2 signal
77 Acidosis Hyperchloraemic 3 12.9 12.9 signal
78 Preterm Premature Rupture Of Membranes 6 12.8 12.8 signal
79 Metamorphopsia 9 12.4 12.5 signal
80 Pulmonary Valve Incompetence 7 12.4 12.4 signal
81 Psychomotor Skills Impaired 12 11.6 11.6 signal
82 Dysphemia 20 11.6 11.6 signal
83 Cerebellar Syndrome 10 11.5 11.5 signal
84 Shoulder Fracture 7 11.4 11.4 signal
85 Fear Of Death 10 11.3 11.4 signal
86 Intrusive Thoughts 5 11.2 11.2 signal
87 Clumsiness 12 11.1 11.1 signal
88 Tongue Biting 9 11.0 11.0 signal
89 Living In Residential Institution 8 10.8 10.8 signal
90 Face Injury 16 10.7 10.7 signal
91 Labile Blood Pressure 5 10.7 10.7 signal
92 Anticonvulsant Drug Level Decreased 6 10.7 10.7 signal
93 Bite 3 10.5 10.5 signal
94 Excessive Eye Blinking 6 10.3 10.3 signal
95 Somnolence 807 10.2 11.2 signal
96 Self-destructive Behaviour 3 10.2 10.2 signal
97 Brain Fog 58 10.1 10.1 signal
98 Nystagmus 21 10.0 10.1 signal
99 Sedation 103 10.0 10.1 signal
100 Intercepted Product Prescribing Error 5 9.8 9.8 signal
101 Eye Contusion 8 9.6 9.6 signal
102 Drooling 26 9.6 9.6 signal
103 Somatic Symptom Disorder 4 9.4 9.4 signal
104 Cerebral Venous Sinus Thrombosis 3 9.3 9.3 signal
105 Communication Disorder 14 9.3 9.3 signal
106 Moaning 4 9.1 9.1 signal
107 Labelled Drug-drug Interaction Issue 5 9.0 9.0 signal
108 Apathy 51 8.9 8.9 signal
109 Dysarthria 132 8.9 9.0 signal
110 Laziness 6 8.9 8.9 signal
111 Reading Disorder 8 8.9 8.9 signal
112 Intestinal Pseudo-obstruction 3 8.8 8.8 signal
113 Product Prescribing Error 79 8.5 8.5 signal
114 Wrong Dose 8 8.4 8.4 signal
115 Aortic Valve Incompetence 14 8.3 8.3 signal
116 Mouth Injury 5 8.3 8.3 signal
117 Personality Change 30 8.1 8.2 signal
118 Product Use Issue 599 8.1 8.7 signal
119 Hyperammonaemia 16 8.1 8.1 signal
120 Tricuspid Valve Incompetence 25 8.0 8.0 signal
121 Wrong Schedule 3 8.0 8.0 signal
122 Anticholinergic Syndrome 5 8.0 8.0 signal
123 Hypervigilance 3 7.9 7.9 signal
124 Slow Response To Stimuli 4 7.8 7.9 signal
125 Product Availability Issue 69 7.8 7.9 signal
126 Hypovitaminosis 4 7.7 7.7 signal
127 Epilepsy 92 7.6 7.7 signal
128 Balance Disorder 255 7.5 7.7 signal
129 Psychotic Behaviour 3 7.4 7.4 signal
130 Product Blister Packaging Issue 3 7.4 7.4 signal
131 Head Injury 91 7.3 7.4 signal
132 Intentional Underdose 21 7.3 7.3 signal
133 Echocardiogram Abnormal 4 7.3 7.3 signal
134 Endotracheal Intubation 8 7.2 7.3 signal
135 Binge Eating 3 7.1 7.1 signal
136 Language Disorder 6 7.0 7.0 signal
137 Coordination Abnormal 39 7.0 7.1 signal
138 Eye Movement Disorder 19 7.0 7.0 signal
139 Folate Deficiency 3 6.6 6.6 signal
140 Hyporesponsive To Stimuli 3 6.6 6.6 signal
141 Circumstance Or Information Capable Of Leading To Medication Error 87 6.6 6.6 signal
142 Hiccups 21 6.5 6.5 signal
143 Aphasia 75 6.3 6.3 signal
144 Bradyphrenia 16 6.2 6.2 signal
145 Affective Disorder 19 6.1 6.1 signal
146 Walking Disability 5 6.0 6.0 signal
147 Educational Problem 4 6.0 6.0 signal
148 Encephalopathy 58 6.0 6.0 signal
149 Tonic Clonic Movements 3 5.9 5.9 signal
150 Spinal Cord Injury 4 5.8 5.8 signal
151 Mood Altered 61 5.7 5.7 signal
152 Drug Interaction 354 5.6 5.9 signal
153 Head Titubation 3 5.5 5.5 signal
154 Ammonia Increased 11 5.5 5.5 signal
155 Posture Abnormal 7 5.5 5.5 signal
156 Impatience 4 5.4 5.4 signal
157 Intellectual Disability 3 5.4 5.4 signal
158 Incorrect Route Of Product Administration 35 5.3 5.3 signal
159 Strabismus 6 5.2 5.2 signal
160 Intentional Dose Omission 55 5.1 5.1 signal
161 Anger 68 5.1 5.1 signal
162 Craniocerebral Injury 6 5.1 5.1 signal
163 Sedation Complication 5 5.1 5.1 signal
164 Physical Deconditioning 5 5.1 5.1 signal
165 Drug Level Increased 33 5.0 5.1 signal
166 Walking Aid User 13 5.0 5.0 signal
167 Dysstasia 57 4.9 5.0 signal
168 Impulse-control Disorder 4 4.9 4.9 signal
169 Daydreaming 3 4.9 4.9 signal
170 Concussion 15 4.9 4.9 signal
171 Altered State Of Consciousness 41 4.8 4.8 signal
172 Oculogyric Crisis 4 4.8 4.8 signal
173 Wrong Technique In Product Usage Process 376 4.7 4.9 signal
174 Abnormal Behaviour 74 4.7 4.7 signal
175 Therapy Interrupted 128 4.7 4.8 signal
176 Lethargy 106 4.7 4.7 signal
177 Eosinophilia 32 4.6 4.6 signal
178 Rehabilitation Therapy 7 4.6 4.6 signal
179 Dysgraphia 12 4.6 4.6 signal
180 Memory Impairment 248 4.6 4.7 signal
181 Gastrointestinal Hypomotility 4 4.5 4.5 signal
182 Psychomotor Retardation 5 4.5 4.5 signal
183 Seizure Like Phenomena 3 4.5 4.5 signal
184 Therapy Change 17 4.5 4.5 signal
185 Sleep Talking 3 4.4 4.4 signal
186 Gait Inability 58 4.4 4.5 signal
187 Tongue Coated 3 4.4 4.4 signal
188 Enuresis 7 4.4 4.4 signal
189 Priapism 6 4.4 4.4 signal
190 Bradykinesia 10 4.3 4.3 signal
191 Neck Injury 5 4.3 4.3 signal
192 Emergency Care 5 4.3 4.3 signal
193 Drug Withdrawal Convulsions 3 4.3 4.3 signal
194 Mitral Valve Incompetence 19 4.2 4.3 signal
195 Self-injurious Ideation 7 4.2 4.2 signal
196 Impaired Driving Ability 19 4.2 4.2 signal
197 Disturbance In Attention 88 4.1 4.2 signal
198 Psychiatric Symptom 12 4.1 4.1 signal
199 Tunnel Vision 3 4.1 4.1 signal
200 Hepatic Steatosis 30 4.1 4.1 signal
201 Impulsive Behaviour 6 4.0 4.0 signal
202 Urinary Tract Infection Bacterial 4 4.0 4.0 signal
203 Drug Intolerance 152 4.0 4.1 signal
204 Drug Level Decreased 16 4.0 4.0 signal
205 Mechanical Ventilation 3 4.0 4.0 no signal
206 Hostility 4 3.9 3.9 signal
207 Aggression 78 3.9 4.0 signal
208 Stupor 5 3.9 3.9 signal
209 Impaired Work Ability 33 3.9 3.9 signal
210 Personality Disorder 4 3.8 3.8 signal
211 Cognitive Disorder 70 3.8 3.8 signal
212 Overweight 8 3.8 3.8 signal
213 Muscle Contracture 3 3.7 3.7 no signal
214 Gait Disturbance 281 3.7 3.8 signal
215 Hypokinesia 21 3.7 3.7 signal
216 Pneumonia Aspiration 36 3.7 3.7 signal
217 Febrile Bone Marrow Aplasia 6 3.6 3.6 signal
218 Drug Tolerance Decreased 4 3.6 3.6 signal
219 Hand Fracture 10 3.6 3.6 signal
220 Mental Impairment 34 3.5 3.6 signal
221 Erectile Dysfunction 36 3.5 3.5 signal
222 Incoherent 9 3.5 3.5 signal
223 Agitation 102 3.5 3.5 signal
224 Hyperprolactinaemia 9 3.5 3.5 signal
225 Sluggishness 14 3.5 3.5 signal
226 Fall 458 3.5 3.6 signal
227 Product Preparation Issue 8 3.5 3.5 signal
228 Colonoscopy 3 3.4 3.4 no signal
229 Negative Thoughts 4 3.4 3.4 signal
230 Speech Disorder 71 3.4 3.4 signal
231 Decreased Interest 8 3.4 3.4 signal
232 Myoclonus 16 3.4 3.4 signal
233 Amnesia 87 3.4 3.4 signal
234 Suicidal Ideation 122 3.4 3.4 signal
235 Mydriasis 17 3.4 3.4 signal
236 Flat Affect 3 3.3 3.3 no signal
237 Dizziness 653 3.3 3.5 signal
238 Eyelid Disorder 3 3.3 3.3 no signal
239 Muscle Twitching 30 3.3 3.3 signal
240 Hospitalisation 196 3.3 3.3 signal
241 Thinking Abnormal 24 3.2 3.2 signal
242 Product Supply Issue 9 3.2 3.2 signal
243 Irritability 76 3.2 3.2 signal
244 Stress 90 3.2 3.2 signal
245 Screaming 8 3.2 3.2 signal
246 Feeling Abnormal 297 3.1 3.2 signal
247 Therapy Cessation 63 3.1 3.1 signal
248 Learning Disorder 3 3.1 3.1 no signal
249 Vision Blurred 165 3.1 3.1 signal
250 Skin Laceration 13 3.0 3.0 signal
251 Small For Dates Baby 6 3.0 3.0 signal
252 Loss Of Personal Independence In Daily Activities 57 3.0 3.0 signal
253 Emotional Disorder 37 3.0 3.0 signal
254 Mood Swings 38 3.0 3.0 signal
255 Product Packaging Quantity Issue 13 3.0 3.0 signal
256 Swollen Tongue 37 3.0 3.0 signal
257 Crying 43 3.0 3.0 signal
258 Product Administration Interrupted 9 3.0 3.0 signal
259 Abortion Induced 11 3.0 3.0 signal
260 Depression Suicidal 4 2.9 2.9 no signal
261 Paranoia 20 2.9 2.9 signal
262 Hypomenorrhoea 3 2.9 2.9 no signal
263 Tooth Injury 5 2.9 2.9 signal
264 Adverse Event 104 2.9 2.9 signal
265 Impaired Quality Of Life 16 2.8 2.8 signal
266 Mania 18 2.8 2.8 signal
267 Facial Bones Fracture 4 2.8 2.8 no signal
268 Prescribed Overdose 21 2.7 2.7 signal
269 Initial Insomnia 11 2.7 2.7 signal
270 Head Discomfort 19 2.7 2.7 signal
271 Eating Disorder 23 2.7 2.7 signal
272 Fatigue 831 2.7 2.9 signal
273 Product Communication Issue 9 2.7 2.7 signal
274 Vertigo 64 2.7 2.7 signal
275 Clavicle Fracture 4 2.6 2.6 no signal
276 Mixed Liver Injury 3 2.6 2.6 no signal
277 Adverse Drug Reaction 92 2.6 2.6 signal
278 Stridor 3 2.6 2.6 no signal
279 Product Distribution Issue 9 2.6 2.6 signal
280 Aspiration 11 2.6 2.6 signal
281 Hospice Care 10 2.6 2.6 signal
282 Polydipsia 4 2.6 2.6 no signal
283 Eye Injury 3 2.5 2.5 no signal
284 Motor Dysfunction 10 2.5 2.5 signal
285 Thermal Burn 7 2.5 2.5 signal
286 Tremor 162 2.5 2.5 signal
287 Loss Of Consciousness 124 2.4 2.5 signal
288 Diastolic Dysfunction 3 2.4 2.4 no signal
289 Blepharospasm 6 2.4 2.4 no signal
290 Sleep Terror 4 2.4 2.4 no signal
291 Hepatic Pain 4 2.4 2.4 no signal
292 Product Prescribing Issue 19 2.4 2.4 signal
293 Left Ventricular Hypertrophy 4 2.4 2.4 no signal
294 Back Injury 10 2.3 2.3 signal
295 Appetite Disorder 6 2.3 2.3 no signal
296 Normal Newborn 5 2.3 2.3 no signal
297 Drug Level Below Therapeutic 5 2.3 2.3 no signal
298 Confusional State 147 2.3 2.3 signal
299 Disorientation 36 2.3 2.3 signal
300 Product Physical Issue 18 2.3 2.3 signal
301 Myasthenia Gravis 7 2.2 2.2 no signal
302 Rebound Effect 10 2.2 2.2 signal
303 Hallucination, Auditory 14 2.2 2.2 signal
304 Euphoric Mood 9 2.2 2.2 signal
305 Suicide Attempt 53 2.2 2.2 signal
306 Obsessive-compulsive Disorder 7 2.2 2.2 no signal
307 Functional Gastrointestinal Disorder 3 2.2 2.2 no signal
308 Dyskinesia 35 2.2 2.2 signal
309 Skin Abrasion 4 2.2 2.2 no signal
310 Logorrhoea 3 2.1 2.1 no signal
311 Tibia Fracture 4 2.1 2.1 no signal
312 Hangover 3 2.1 2.1 no signal
313 Nervousness 44 2.1 2.1 signal
314 Hepatic Function Abnormal 31 2.1 2.1 signal
315 Depressed Level Of Consciousness 33 2.1 2.1 signal
316 Product Dose Omission In Error 22 2.1 2.1 signal
317 Quality Of Life Decreased 11 2.1 2.1 signal
318 Intentional Overdose 52 2.1 2.1 signal
319 Decreased Appetite 186 2.0 2.1 signal
320 Hepatic Enzyme Abnormal 4 2.0 2.0 no signal
321 Hypotonia 8 2.0 2.0 no signal
322 Blood Sodium Decreased 15 2.0 2.0 signal
323 Snoring 3 2.0 2.0 no signal
324 Panic Attack 29 2.0 2.0 signal
325 Groin Pain 7 2.0 2.0 no signal
326 Photopsia 5 2.0 2.0 no signal
327 Thirst 14 2.0 2.0 no signal
328 Loss Of Control Of Legs 3 2.0 2.0 no signal
329 Fear 21 2.0 2.0 no signal
330 Pelvic Fracture 6 2.0 2.0 no signal
331 Periorbital Oedema 4 1.9 1.9 no signal
332 Malabsorption 4 1.9 1.9 no signal
333 Hepatotoxicity 17 1.9 1.9 no signal
334 Venous Thrombosis 3 1.9 1.9 no signal
335 Somnambulism 5 1.9 1.9 no signal
336 Off Label Use 658 1.9 2.0 no signal
337 Abnormal Dreams 21 1.9 1.9 no signal
338 Cerebral Atrophy 3 1.9 1.9 no signal
339 Sars-cov-2 Test Positive 10 1.9 1.9 no signal
340 Incorrect Dose Administered 168 1.9 1.9 no signal
341 Insomnia 199 1.9 1.9 no signal
342 Drug Reaction With Eosinophilia And Systemic Symptoms 19 1.9 1.9 no signal
343 Bruxism 4 1.9 1.9 no signal
344 Drug Resistance 19 1.9 1.9 no signal
345 Tic 4 1.9 1.9 no signal
346 Autism Spectrum Disorder 4 1.8 1.8 no signal
347 Dizziness Postural 7 1.8 1.8 no signal
348 Maternal Exposure During Pregnancy 64 1.8 1.8 no signal
349 Depression 164 1.8 1.8 no signal
350 Suicidal Behaviour 3 1.8 1.8 no signal
351 Hallucinations, Mixed 3 1.8 1.8 no signal
352 Inability To Afford Medication 7 1.8 1.8 no signal
353 Ankle Fracture 11 1.8 1.8 no signal
354 Depressed Mood 37 1.8 1.8 no signal
355 Feeding Disorder 14 1.8 1.8 no signal
356 Hepatic Lesion 3 1.8 1.8 no signal
357 Toxic Skin Eruption 7 1.8 1.8 no signal
358 Nightmare 24 1.7 1.7 no signal
359 Dry Throat 7 1.7 1.7 no signal
360 Withdrawal Syndrome 29 1.7 1.7 no signal
361 Grip Strength Decreased 6 1.7 1.7 no signal
362 Cerebral Disorder 5 1.7 1.7 no signal
363 Gamma-glutamyltransferase Increased 15 1.7 1.7 no signal
364 Wheelchair User 3 1.7 1.7 no signal
365 Parosmia 5 1.7 1.7 no signal
366 Incontinence 7 1.7 1.7 no signal
367 Nephrolithiasis 30 1.7 1.7 no signal
368 Tension 4 1.7 1.7 no signal
369 Migraine 62 1.7 1.7 no signal
370 Decreased Activity 7 1.7 1.7 no signal
371 Illness 65 1.6 1.6 no signal
372 Product Packaging Issue 6 1.6 1.6 no signal
373 Abortion Spontaneous 26 1.6 1.6 no signal
374 Road Traffic Accident 27 1.6 1.6 no signal
375 Ocular Discomfort 7 1.6 1.6 no signal
376 Performance Status Decreased 3 1.6 1.6 no signal
377 Urinary Incontinence 19 1.6 1.6 no signal
378 Apnoea 5 1.6 1.6 no signal
379 Body Temperature Increased 13 1.6 1.6 no signal
380 Visual Impairment 78 1.6 1.6 no signal
381 Impaired Gastric Emptying 8 1.6 1.6 no signal
382 Hypogammaglobulinaemia 4 1.6 1.6 no signal
383 Frustration Tolerance Decreased 5 1.6 1.6 no signal
384 Chromaturia 14 1.6 1.6 no signal
385 Choking 12 1.6 1.6 no signal
386 Dementia 17 1.5 1.5 no signal
387 Gastrointestinal Sounds Abnormal 3 1.5 1.5 no signal
388 Psychotic Disorder 18 1.5 1.5 no signal
389 Bedridden 8 1.5 1.5 no signal
390 Headache 380 1.5 1.6 no signal
391 Hyponatraemia 34 1.5 1.5 no signal
392 Adverse Reaction 8 1.5 1.5 no signal
393 Restlessness 22 1.5 1.5 no signal
394 Sleep Disorder 42 1.5 1.5 no signal
395 Product Dispensing Error 13 1.5 1.5 no signal
396 Limb Injury 16 1.5 1.5 no signal
397 Drug Tolerance 3 1.5 1.5 no signal
398 Maternal Exposure Before Pregnancy 4 1.5 1.5 no signal
399 Coma 28 1.5 1.5 no signal
400 Hemiparesis 10 1.5 1.5 no signal
401 Dysphagia 55 1.5 1.5 no signal
402 Anxiety 165 1.5 1.5 no signal
403 Respiratory Syncytial Virus Infection 5 1.5 1.5 no signal
404 Catatonia 3 1.5 1.5 no signal
405 Accidental Overdose 21 1.5 1.5 no signal
406 Expired Product Administered 19 1.4 1.4 no signal
407 Toxicity To Various Agents 95 1.4 1.4 no signal
408 Poor Quality Sleep 12 1.4 1.4 no signal
409 Subdural Haematoma 8 1.4 1.4 no signal
410 Panic Reaction 4 1.4 1.4 no signal
411 Asthenopia 3 1.4 1.4 no signal
412 Upper Limb Fracture 11 1.4 1.4 no signal
413 Limb Discomfort 17 1.4 1.4 no signal
414 Choking Sensation 3 1.4 1.4 no signal
415 Lymphadenopathy 19 1.4 1.4 no signal
416 Rib Fracture 11 1.4 1.4 no signal
417 Intentional Product Use Issue 47 1.4 1.4 no signal
418 Increased Appetite 10 1.3 1.3 no signal
419 Overdose 115 1.3 1.3 no signal
420 Hip Fracture 17 1.3 1.3 no signal
421 Neurological Symptom 3 1.3 1.3 no signal
422 Peroneal Nerve Palsy 3 1.3 1.3 no signal
423 Mental Disorder 23 1.3 1.3 no signal
424 Cardiac Valve Disease 3 1.3 1.3 no signal
425 Drug-induced Liver Injury 16 1.3 1.3 no signal
426 Metabolic Disorder 3 1.3 1.3 no signal
427 Delusion 8 1.3 1.3 no signal
428 Liver Function Test Increased 11 1.3 1.3 no signal
429 Gynaecomastia 16 1.3 1.3 no signal
430 Ligament Sprain 5 1.3 1.3 no signal
431 Rash 218 1.3 1.3 no signal
432 Weight Decreased 140 1.3 1.3 no signal
433 Wrist Fracture 6 1.3 1.3 no signal
434 Taste Disorder 10 1.3 1.3 no signal
435 Lactic Acidosis 16 1.3 1.3 no signal
436 Seasonal Allergy 7 1.3 1.3 no signal
437 Ill-defined Disorder 30 1.2 1.2 no signal
438 Swelling Of Eyelid 3 1.2 1.2 no signal
439 Secretion Discharge 6 1.2 1.2 no signal
440 Middle Insomnia 9 1.2 1.2 no signal
441 Scratch 5 1.2 1.2 no signal
442 Contusion 46 1.2 1.2 no signal
443 Facial Paralysis 4 1.2 1.2 no signal
444 Asthenia 177 1.2 1.2 no signal
445 Sleep Apnoea Syndrome 9 1.2 1.2 no signal
446 Bradycardia 25 1.2 1.2 no signal
447 Unresponsive To Stimuli 12 1.2 1.2 no signal
448 Underdose 34 1.2 1.2 no signal
449 Hepatitis Acute 3 1.2 1.2 no signal
450 Muscle Strain 4 1.2 1.2 no signal
451 Product Use Complaint 7 1.1 1.1 no signal
452 Spinal Fracture 9 1.1 1.1 no signal
453 Coronavirus Infection 3 1.1 1.1 no signal
454 Anal Incontinence 4 1.1 1.1 no signal
455 Hunger 6 1.1 1.1 no signal
456 Intentional Self-injury 9 1.1 1.1 no signal
457 Loss Of Libido 4 1.1 1.1 no signal
458 Gastroenteritis Viral 8 1.1 1.1 no signal
459 General Physical Condition Abnormal 3 1.1 1.1 no signal
460 Heart Rate Irregular 10 1.1 1.1 no signal
461 Respiration Abnormal 3 1.1 1.1 no signal
462 Brain Neoplasm 4 1.1 1.1 no signal
463 Lymphoedema 3 1.1 1.1 no signal
464 Constipation 94 1.1 1.1 no signal
465 Muscle Tightness 7 1.1 1.1 no signal
466 Mental Status Changes 12 1.1 1.1 no signal
467 Surgery 25 1.1 1.1 no signal
468 Premature Baby 13 1.1 1.1 no signal
469 Hallucination, Visual 9 1.1 1.1 no signal
470 Rash Erythematous 20 1.1 1.1 no signal
471 Hallucination 32 1.1 1.1 no signal
472 Bacteraemia 5 1.1 1.1 no signal
473 Retching 9 1.1 1.1 no signal
474 Muscular Weakness 48 1.1 1.1 no signal
475 Foot Fracture 8 1.1 1.1 no signal
476 Accident 5 1.1 1.1 no signal
477 Paraesthesia Oral 6 1.1 1.1 no signal
478 Vomiting 195 1.1 1.1 no signal
479 Visual Field Defect 3 1.1 1.1 no signal
480 Pancreatitis 22 1.1 1.1 no signal
481 Faeces Soft 3 1.0 1.0 no signal
482 Ear Pain 8 1.0 1.0 no signal
483 Condition Aggravated 124 1.0 1.0 no signal
484 Mouth Haemorrhage 3 1.0 1.0 no signal
485 Rash Pruritic 22 1.0 1.0 no signal
486 Respiratory Depression 5 1.0 1.0 no signal
487 Libido Decreased 5 1.0 1.0 no signal
488 Brain Injury 4 1.0 1.0 no signal
489 Dissociation 3 1.0 1.0 no signal
490 Eye Disorder 13 1.0 1.0 no signal
491 Bowel Movement Irregularity 3 1.0 1.0 no signal
492 Eye Discharge 4 1.0 1.0 no signal
493 Aphthous Ulcer 3 1.0 1.0 no signal
494 Urinary Retention 13 1.0 1.0 no signal
495 Low Density Lipoprotein Increased 3 1.0 1.0 no signal
496 Acute Generalised Exanthematous Pustulosis 3 1.0 1.0 no signal
497 Atrioventricular Block 3 1.0 1.0 no signal
498 Treatment Noncompliance 21 1.0 1.0 no signal
499 Exposure During Pregnancy 24 1.0 1.0 no signal
500 Menstruation Delayed 4 1.0 1.0 no signal
501 Palpitations 45 1.0 1.0 no signal
502 Petechiae 4 1.0 1.0 no signal
503 Oral Candidiasis 5 1.0 1.0 no signal
504 Drug Screen Positive 3 1.0 1.0 no signal
505 Joint Dislocation 4 1.0 1.0 no signal
506 Ear Infection 10 1.0 1.0 no signal
507 Nasal Discomfort 3 1.0 1.0 no signal
508 Joint Injury 8 0.9 0.9 no signal
509 Gastrointestinal Disorder 33 0.9 0.9 no signal
510 Sensory Disturbance 6 0.9 0.9 no signal
511 Dry Mouth 30 0.9 0.9 no signal
512 Pharyngitis Streptococcal 4 0.9 0.9 no signal
513 Swelling Face 24 0.9 0.9 no signal
514 Upper-airway Cough Syndrome 3 0.9 0.9 no signal
515 Oesophagitis 4 0.9 0.9 no signal
516 Muscle Injury 3 0.9 0.9 no signal
517 Photosensitivity Reaction 6 0.9 0.9 no signal
518 Psychomotor Hyperactivity 6 0.9 0.9 no signal
519 Feeling Cold 10 0.9 0.9 no signal
520 Therapeutic Response Unexpected 16 0.9 0.9 no signal
521 Drug Effect Less Than Expected 5 0.9 0.9 no signal
522 Heart Rate Increased 34 0.9 0.9 no signal
523 Night Sweats 11 0.9 0.9 no signal
524 Spinal Pain 4 0.9 0.9 no signal
525 Injury 24 0.9 0.9 no signal
526 Blood Iron Decreased 4 0.9 0.9 no signal
527 Hepatic Enzyme Increased 23 0.9 0.9 no signal
528 Gastrointestinal Infection 3 0.8 0.8 no signal
529 Oropharyngeal Discomfort 3 0.8 0.8 no signal
530 Respiratory Disorder 10 0.8 0.8 no signal
531 Haemorrhage Intracranial 5 0.8 0.8 no signal
532 Hypoaesthesia Oral 5 0.8 0.8 no signal
533 Urinary Tract Infection 56 0.8 0.8 no signal
534 Abdominal Discomfort 55 0.8 0.8 no signal
535 Weight Increased 73 0.8 0.8 no signal
536 Therapeutic Product Effect Incomplete 23 0.8 0.8 no signal
537 Product Use In Unapproved Indication 79 0.8 0.8 no signal
538 Syncope 32 0.8 0.8 no signal
539 Nasopharyngitis 59 0.8 0.8 no signal
540 Inappropriate Schedule Of Product Administration 56 0.8 0.8 no signal
541 Posterior Reversible Encephalopathy Syndrome 3 0.8 0.8 no signal
542 Nausea 248 0.8 0.8 no signal
543 Lower Limb Fracture 6 0.8 0.8 no signal
544 Pharyngeal Swelling 3 0.8 0.8 no signal
545 Premature Delivery 5 0.8 0.8 no signal
546 Rash Papular 7 0.8 0.8 no signal
547 Oral Pain 7 0.8 0.8 no signal
548 Feeling Hot 19 0.8 0.8 no signal
549 Abdominal Pain Upper 63 0.8 0.8 no signal
550 Medication Error 17 0.8 0.8 no signal
551 Oxygen Saturation Decreased 17 0.8 0.8 no signal
552 Tinnitus 14 0.8 0.8 no signal
553 Bladder Disorder 3 0.8 0.8 no signal
554 Salivary Hypersecretion 3 0.8 0.8 no signal
555 Pericarditis 5 0.8 0.8 no signal
556 Amenorrhoea 5 0.8 0.8 no signal
557 Ovarian Cyst 3 0.8 0.8 no signal
558 Malaise 131 0.8 0.7 no signal
559 Discomfort 18 0.8 0.7 no signal
560 Sinus Congestion 4 0.7 0.7 no signal
561 Covid-19 52 0.7 0.7 no signal
562 Hypoaesthesia 44 0.7 0.7 no signal
563 Ear Discomfort 3 0.7 0.7 no signal
564 Central Nervous System Lesion 4 0.7 0.7 no signal
565 Orthostatic Hypotension 5 0.7 0.7 no signal
566 Cold Sweat 5 0.7 0.7 no signal
567 Flatulence 16 0.7 0.7 no signal
568 Movement Disorder 9 0.7 0.7 no signal
569 Laryngitis 3 0.7 0.7 no signal
570 Hypophagia 7 0.7 0.7 no signal
571 Extra Dose Administered 11 0.7 0.7 no signal
572 Dysphonia 16 0.7 0.7 no signal
573 Nasal Congestion 16 0.7 0.7 no signal
574 Tooth Fracture 3 0.7 0.7 no signal
575 Lip Swelling 9 0.7 0.7 no signal
576 Oropharyngeal Pain 25 0.7 0.7 no signal
577 Insurance Issue 4 0.7 0.7 no signal
578 Drug Ineffective 351 0.7 0.7 no signal
579 Myocarditis 3 0.7 0.7 no signal
580 Unevaluable Event 20 0.7 0.7 no signal
581 Dermatitis Contact 3 0.7 0.7 no signal
582 Cholecystectomy 3 0.7 0.7 no signal
583 Eructation 5 0.7 0.7 no signal
584 Pulmonary Embolism 25 0.7 0.7 no signal
585 Feeling Jittery 5 0.7 0.7 no signal
586 Pericardial Effusion 6 0.7 0.7 no signal
587 Alanine Aminotransferase Increased 16 0.7 0.7 no signal
588 Thrombocytopenia 29 0.7 0.7 no signal
589 Rash Macular 9 0.7 0.7 no signal
590 Covid-19 Pneumonia 3 0.6 0.6 no signal
591 Sinus Disorder 5 0.6 0.6 no signal
592 Respiratory Arrest 7 0.6 0.6 no signal
593 Influenza 28 0.6 0.6 no signal
594 Liver Disorder 11 0.6 0.6 no signal
595 Presyncope 6 0.6 0.6 no signal
596 Paraesthesia 39 0.6 0.6 no signal
597 Blood Potassium Increased 4 0.6 0.6 no signal
598 Aspartate Aminotransferase Increased 13 0.6 0.6 no signal
599 Hypersensitivity 45 0.6 0.6 no signal
600 Cardiac Arrest 20 0.6 0.6 no signal
601 Pneumonia 78 0.6 0.6 no signal
602 Tooth Extraction 3 0.6 0.6 no signal
603 Dermatitis Allergic 3 0.6 0.6 no signal
604 Muscle Atrophy 3 0.6 0.6 no signal
605 Cardio-respiratory Arrest 10 0.6 0.6 no signal
606 Circulatory Collapse 4 0.6 0.6 no signal
607 Alopecia 46 0.6 0.6 no signal
608 Pancytopenia 13 0.6 0.6 no signal
609 Neurotoxicity 4 0.6 0.6 no signal
610 Dysmenorrhoea 3 0.6 0.6 no signal
611 Hyperkalaemia 8 0.6 0.6 no signal
612 Gastritis 6 0.6 0.6 no signal
613 Immune System Disorder 3 0.6 0.6 no signal
614 Pruritus 86 0.6 0.6 no signal
615 Tooth Infection 3 0.6 0.6 no signal
616 Drug Eruption 4 0.6 0.6 no signal
617 Heart Rate Decreased 8 0.6 0.6 no signal
618 Femur Fracture 7 0.6 0.6 no signal
619 Therapeutic Product Effect Decreased 10 0.6 0.6 no signal
620 Dehydration 30 0.6 0.6 no signal
621 Sneezing 5 0.6 0.6 no signal
622 Myalgia 37 0.6 0.5 no signal
623 Hyperhidrosis 28 0.5 0.5 no signal
624 Drug Ineffective For Unapproved Indication 12 0.5 0.5 no signal
625 Blister 12 0.5 0.5 no signal
626 Productive Cough 10 0.5 0.5 no signal
627 Fracture 4 0.5 0.5 no signal
628 Viral Infection 7 0.5 0.5 no signal
629 Mobility Decreased 15 0.5 0.5 no signal
630 Acute Respiratory Failure 4 0.5 0.5 no signal
631 Paralysis 3 0.5 0.5 no signal
632 International Normalised Ratio Increased 6 0.5 0.5 no signal
633 Musculoskeletal Stiffness 18 0.5 0.5 no signal
634 Disability 4 0.5 0.5 no signal
635 Blood Alkaline Phosphatase Increased 5 0.5 0.5 no signal
636 Colon Cancer 3 0.5 0.5 no signal
637 Drug Hypersensitivity 39 0.5 0.5 no signal
638 Leukopenia 10 0.5 0.5 no signal
639 Product Administration Error 4 0.5 0.5 no signal
640 Cerebrovascular Accident 34 0.5 0.5 no signal
641 Hypoxia 7 0.5 0.5 no signal
642 Eczema 10 0.5 0.5 no signal
643 Chest Discomfort 20 0.5 0.5 no signal
644 Skin Discolouration 9 0.5 0.5 no signal
645 Thyroid Disorder 3 0.5 0.5 no signal
646 Nervous System Disorder 6 0.5 0.5 no signal
647 Haemorrhage 20 0.5 0.5 no signal
648 Cyanosis 3 0.5 0.5 no signal
649 Metabolic Acidosis 6 0.5 0.5 no signal
650 Chest Pain 35 0.5 0.5 no signal
651 Abscess 3 0.5 0.5 no signal
652 Diarrhoea 121 0.5 0.5 no signal
653 Irritable Bowel Syndrome 4 0.5 0.5 no signal
654 Intentional Product Misuse 16 0.5 0.5 no signal
655 Rash Maculo-papular 4 0.5 0.5 no signal
656 Cough 50 0.5 0.4 no signal
657 Completed Suicide 15 0.5 0.4 no signal
658 Myelosuppression 6 0.4 0.4 no signal
659 No Adverse Event 31 0.4 0.4 no signal
660 Musculoskeletal Discomfort 3 0.4 0.4 no signal
661 Herpes Zoster 10 0.4 0.4 no signal
662 Blood Cholesterol Increased 8 0.4 0.4 no signal
663 Osteoporosis 7 0.4 0.4 no signal
664 Blood Triglycerides Increased 3 0.4 0.4 no signal
665 Cerebral Haemorrhage 6 0.4 0.4 no signal
666 Lacrimation Increased 5 0.4 0.4 no signal
667 Blood Pressure Fluctuation 4 0.4 0.4 no signal
668 Leukocytosis 3 0.4 0.4 no signal
669 Blood Pressure Decreased 11 0.4 0.4 no signal
670 Toothache 3 0.4 0.4 no signal
671 Restless Legs Syndrome 3 0.4 0.4 no signal
672 Pyrexia 57 0.4 0.4 no signal
673 Photophobia 3 0.4 0.4 no signal
674 Angioedema 7 0.4 0.4 no signal
675 Haematemesis 4 0.4 0.4 no signal
676 Therapy Non-responder 7 0.4 0.4 no signal
677 Back Pain 36 0.4 0.4 no signal
678 Dystonia 3 0.4 0.4 no signal
679 Haematoma 4 0.4 0.4 no signal
680 Haemorrhoids 3 0.4 0.4 no signal
681 Menstruation Irregular 4 0.4 0.4 no signal
682 Urticaria 25 0.4 0.4 no signal
683 Thrombosis 12 0.4 0.4 no signal
684 Pregnancy 3 0.4 0.4 no signal
685 Epistaxis 11 0.4 0.4 no signal
686 Diverticulitis 4 0.4 0.4 no signal
687 Delirium 5 0.4 0.4 no signal
688 Dry Eye 7 0.4 0.4 no signal
689 Acne 11 0.4 0.4 no signal
690 Knee Arthroplasty 3 0.4 0.4 no signal
691 Wound 4 0.4 0.4 no signal
692 Tooth Loss 3 0.4 0.4 no signal
693 Dyspepsia 14 0.4 0.4 no signal
694 Mouth Ulceration 3 0.4 0.4 no signal
695 Burning Sensation 10 0.4 0.4 no signal
696 Muscle Spasms 26 0.4 0.4 no signal
697 Dyspnoea 80 0.4 0.4 no signal
698 Neutropenia 19 0.4 0.4 no signal
699 Hypotension 28 0.4 0.4 no signal
700 Hypoacusis 6 0.4 0.4 no signal
701 Infection 20 0.4 0.3 no signal
702 Cardiac Disorder 13 0.3 0.3 no signal
703 Gastrooesophageal Reflux Disease 11 0.3 0.3 no signal
704 Bone Pain 8 0.3 0.3 no signal
705 Chills 16 0.3 0.3 no signal
706 Foetal Exposure During Pregnancy 11 0.3 0.3 no signal
707 Acute Myocardial Infarction 4 0.3 0.3 no signal
708 Tachycardia 12 0.3 0.3 no signal
709 Renal Injury 4 0.3 0.3 no signal
710 Blood Potassium Decreased 4 0.3 0.3 no signal
711 Hot Flush 10 0.3 0.3 no signal
712 Pain In Extremity 39 0.3 0.3 no signal
713 Stomatitis 8 0.3 0.3 no signal
714 Anaemia 25 0.3 0.3 no signal
715 Eye Pain 7 0.3 0.3 no signal
716 Arrhythmia 6 0.3 0.3 no signal
717 Cystitis 4 0.3 0.3 no signal
718 Acute Kidney Injury 19 0.3 0.3 no signal
719 Neuralgia 3 0.3 0.3 no signal
720 Treatment Failure 10 0.3 0.3 no signal
721 Product Complaint 3 0.3 0.3 no signal
722 Fungal Infection 4 0.3 0.3 no signal
723 Ageusia 3 0.3 0.3 no signal
724 Pain 73 0.3 0.3 no signal
725 Abdominal Pain Lower 3 0.3 0.3 no signal
726 Peripheral Swelling 18 0.3 0.3 no signal
727 Erythema 24 0.3 0.3 no signal
728 Abdominal Distension 12 0.3 0.3 no signal
729 Emotional Distress 14 0.3 0.3 no signal
730 Blood Pressure Increased 17 0.3 0.3 no signal
731 Pallor 3 0.3 0.3 no signal
732 Respiratory Failure 8 0.3 0.3 no signal
733 Skin Irritation 5 0.3 0.3 no signal
734 Hypokalaemia 5 0.3 0.3 no signal
735 Respiratory Distress 3 0.3 0.3 no signal
736 Rhinorrhoea 7 0.3 0.3 no signal
737 Eye Swelling 4 0.3 0.3 no signal
738 Bronchitis 8 0.3 0.3 no signal
739 Swelling 10 0.3 0.3 no signal
740 Ocular Hyperaemia 5 0.3 0.3 no signal
741 Pain In Jaw 3 0.3 0.3 no signal
742 Death 91 0.3 0.3 no signal
743 Tardive Dyskinesia 3 0.3 0.3 no signal
744 Neoplasm Malignant 7 0.3 0.3 no signal
745 Abdominal Pain 24 0.3 0.3 no signal
746 Atrial Fibrillation 10 0.3 0.3 no signal
747 Liver Function Test Abnormal 3 0.3 0.3 no signal
748 Laboratory Test Abnormal 3 0.3 0.3 no signal
749 Hypertension 21 0.3 0.2 no signal
750 Pollakiuria 4 0.2 0.2 no signal
751 General Physical Health Deterioration 11 0.2 0.2 no signal
752 Therapeutic Response Shortened 3 0.2 0.2 no signal
753 Deep Vein Thrombosis 6 0.2 0.2 no signal
754 Arthralgia 38 0.2 0.2 no signal
755 Joint Swelling 11 0.2 0.2 no signal
756 Throat Irritation 4 0.2 0.2 no signal
757 Haematuria 3 0.2 0.2 no signal
758 Upper Respiratory Tract Infection 4 0.2 0.2 no signal
759 Systemic Lupus Erythematosus 3 0.2 0.2 no signal
760 Blood Glucose Decreased 4 0.2 0.2 no signal
761 Lung Disorder 4 0.2 0.2 no signal
762 Dysuria 3 0.2 0.2 no signal
763 Colitis 3 0.2 0.2 no signal
764 Myocardial Infarction 14 0.2 0.2 no signal
765 Fluid Retention 4 0.2 0.2 no signal
766 Inflammation 4 0.2 0.2 no signal
767 Neutrophil Count Decreased 3 0.2 0.2 no signal
768 Blindness 3 0.2 0.2 no signal
769 Anaphylactic Reaction 4 0.2 0.2 no signal
770 Lung Neoplasm Malignant 3 0.2 0.2 no signal
771 Rhabdomyolysis 3 0.2 0.2 no signal
772 Eye Irritation 4 0.2 0.2 no signal
773 Neck Pain 4 0.2 0.2 no signal
774 Skin Burning Sensation 5 0.2 0.2 no signal
775 Rectal Haemorrhage 3 0.2 0.2 no signal
776 Cataract 4 0.2 0.2 no signal
777 Pulmonary Oedema 3 0.2 0.2 no signal
778 Lower Respiratory Tract Infection 3 0.2 0.2 no signal
779 Platelet Count Decreased 7 0.2 0.2 no signal
780 Pleural Effusion 4 0.2 0.2 no signal
781 Oedema Peripheral 8 0.2 0.2 no signal
782 White Blood Cell Count Decreased 7 0.2 0.2 no signal
783 Renal Disorder 3 0.2 0.2 no signal
784 Breast Cancer 6 0.2 0.2 no signal
785 Influenza Like Illness 5 0.2 0.2 no signal
786 Renal Failure 8 0.2 0.2 no signal
787 Sinusitis 6 0.1 0.1 no signal
788 Musculoskeletal Pain 3 0.1 0.1 no signal
789 Haematochezia 3 0.1 0.1 no signal
790 Sepsis 6 0.1 0.1 no signal
791 Diabetes Mellitus 4 0.1 0.1 no signal
792 Accidental Exposure To Product 5 0.1 0.1 no signal
793 Cardiac Failure 4 0.1 0.1 no signal
794 Skin Exfoliation 4 0.1 0.1 no signal
795 Renal Impairment 4 0.1 0.1 no signal
796 Product Storage Error 4 0.1 0.1 no signal
797 Blood Creatinine Increased 3 0.1 0.1 no signal
798 Dry Skin 6 0.1 0.1 no signal
799 Infusion Related Reaction 3 0.1 0.1 no signal
800 Drug Withdrawal Syndrome 4 0.1 0.1 no signal
801 Neuropathy Peripheral 4 0.1 0.1 no signal
802 Arthritis 3 0.1 0.1 no signal
803 Drug Abuse 3 0.1 0.1 no signal
804 Flushing 3 0.1 0.1 no signal
805 Blood Glucose Increased 4 0.1 0.1 no signal
806 Drug Dependence 3 0.0 0.0 no signal