Reaction

Brain Operation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,226 reports · 55 co-occurring drugs

As of the last recalculation, Brain Operation appears in 2,226 FAERS reports alongside 55 co-occurring drug terms. The strongest observed disproportionality signal is BRIVARACETAM (PRR 75.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Brivaracetam	70	75.1	75.7
Vigabatrin	76	50.4	50.7
Lacosamide	177	48.2	48.5
Cenobamate	33	37.5	37.7
Clobazam	62	24.4	24.5
Cannabidiol	55	22.5	22.6
Extended Phenytoin Sodium	37	21.0	21.1
Levetiracetam	242	18.9	18.9
Oxcarbazepine	58	17.1	17.1
Lapatinib	25	15.2	15.2
Phenobarbital	20	13.0	13.0
Temozolomide	28	12.6	12.6
Encorafenib	13	12.3	12.4
Levetiracetam In Sodium Chloride	83	10.4	10.4
Levetiracetam Oral	83	10.4	10.4
Levetiracetam Injection	83	10.4	10.4
Zonisamide	16	10.2	10.2
Divalproex Sodium	48	9.8	9.8
Lamotrigine	114	8.5	8.5
Phenytoin	16	7.2	7.2
Vemurafenib	9	7.0	7.0
Ado-Trastuzumab Emtansine	6	6.7	6.7
Carbamazepine	44	6.2	6.2
Eptinezumab-Jjmr	6	6.2	6.2
Crizotinib	8	5.9	5.9
Fluticasone Propionate And Salmeterol	25	5.7	5.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	5	5.4	5.4
Esketamine Hydrochloride	10	5.3	5.3
Risankizumab-Rzaa	45	5.2	5.2
Rotigotine	7	4.5	4.5
Selexipag	12	4.4	4.4
Capecitabine	42	4.4	4.4
Dabrafenib	9	4.0	4.0
Levodopa	5	3.9	3.9
Niraparib	9	3.8	3.8
Linaclotide	10	3.5	3.5
Trametinib	9	3.5	3.5
Trifluridine And Tipiracil	4	3.5	3.5
Axitinib	7	3.4	3.4
Cenegermin-Bkbj	4	3.1	3.1
Belimumab	10	3.0	3.0
Peginterferon Beta-1A	4	2.9	2.9
Pazopanib Hydrochloride	8	2.8	2.8
Ranolazine	3	2.7	2.7
Tafamidis	3	2.4	2.4
Ambrisentan	30	2.3	2.3
Brexpiprazole	4	2.3	2.3
Erenumab-Aooe	13	2.2	2.2
Somatropin	17	2.2	2.2
Romosozumab-Aqqg	3	2.1	2.1
Dimethyl Fumarate	25	1.9	1.9
Pimavanserin Tartrate	11	1.9	1.9
Droxidopa	4	1.7	1.7
Relugolix	4	1.6	1.6
Cinacalcet Hydrochloride	6	1.2	1.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.