Reaction

Drug Titration Error reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,554 reports · 60 co-occurring drugs

As of the last recalculation, Drug Titration Error appears in 2,554 FAERS reports alongside 60 co-occurring drug terms. The strongest observed disproportionality signal is NALTREXONE HYDROCHLORIDE AND BUPROPION HYDROCHLORIDE (PRR 365.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Naltrexone Hydrochloride And Bupropion Hydrochloride	333	365.8	380.8
Cenobamate	101	102.7	103.9
Siponimod	48	44.7	44.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	46	44.3	44.5
Droxidopa	85	33.2	33.3
Treprostinil	244	17.4	17.4
Gabapentin	560	15.7	15.8
Selexipag	46	14.8	14.8
Tolvaptan	26	14.7	14.7
Oral Semaglutide	126	14.7	14.7
Brexpiprazole	29	14.4	14.4
Vilazodone Hydrochloride	14	12.4	12.4
Propranolol Hydrochloride	99	11.6	11.6
Cariprazine	12	10.6	10.6
Buspirone Hydrochloride	13	9.6	9.7
0Xygen	57	9.6	9.6
Oxygen	57	9.6	9.6
Liraglutide	54	9.1	9.1
Riociguat	34	8.6	8.6
Sodium Oxybate	66	8.3	8.4
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	34	7.9	7.9
Macitentan	65	7.8	7.8
Clobazam	22	7.4	7.4
Brivaracetam	8	7.3	7.3
Sildenafil	50	7.2	7.2
Modafinil	28	7.1	7.1
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	35	7.0	7.0
Epoprostenol	11	6.9	6.9
Methocarbamol Tablets	14	6.8	6.9
Lamotrigine	106	6.8	6.8
Vortioxetine	14	6.7	6.7
Lamotirigine	58	6.7	6.7
Lisdexamfetamine Dimesylate	27	6.7	6.7
Lamotrigine Extended-Release	58	6.7	6.7
Lamotrigine Chewable Dispersible	58	6.7	6.7
Zonisamide	12	6.6	6.6
Cyclobenzaprine Hydrochloride	7	6.4	6.4
Tadalafil	76	6.3	6.3
Ketoprofen	10	6.2	6.2
Guanfacine	6	6.2	6.2
Tirzepatide	113	5.9	5.9
Armodafinil	15	5.8	5.8
Rotigotine	10	5.7	5.7
Lacosamide	25	5.5	5.5
Budesonide, Glycopyrrolate, And Formoterol Fumarate	7	5.5	5.5
Bupropion	29	5.4	5.4
Everolimus Tablets	10	4.9	4.9
Azelastine	10	4.6	4.6
Sildenafil Citrate	67	4.4	4.4
Linaclotide	13	4.0	4.0
Ambrisentan	59	3.9	3.9
Vigabatrin	6	3.4	3.4
Cannabidiol	9	3.1	3.1
Lenvatinib	12	3.0	3.0
Ethyl Alcohol	9	2.7	2.7
Tapentadol Hydrochloride	11	2.7	2.7
Naltrexone	9	2.4	2.4
Paliperidone	6	2.1	2.1
Diroximel Fumarate	3	2.1	2.1
Valbenazine	4	1.3	1.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.