Reaction

Coma Scale Abnormal reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,825 reports · 137 co-occurring drugs

As of the last recalculation, Coma Scale Abnormal appears in 2,825 FAERS reports alongside 137 co-occurring drug terms. The strongest observed disproportionality signal is DIAZEPAM ORAL SOLUTION (CONCENTRATE) (PRR 23.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diazepam Oral Solution (Concentrate)	261	23.7	23.8
Diazepam Oral	261	23.7	23.8
Thiamine Hydrochloride	36	21.6	21.6
Quetiapine Fumarate	82	21.1	21.1
Norepinephrine	30	20.9	20.9
Atropine Sulfate	28	19.3	19.3
Diazepam	283	18.9	19.0
Norepinephrine Bitartrate	33	17.1	17.1
Atropine	19	17.0	17.0
Cenobamate	19	16.9	16.9
Haloperidol	47	14.5	14.5
Venlafaxine	134	14.4	14.4
Everolimus Tablets	32	14.2	14.2
Haloperidol Lactate	47	14.2	14.2
Ethyl Alcohol	49	13.5	13.5
Valproate Sodium	35	12.6	12.6
Temazepam	63	12.6	12.6
Sevoflurane	14	12.5	12.5
Pravastatin Sodium	33	12.4	12.4
Calcitriol Capsules 0.25 Mcg	33	12.3	12.3
Calcitriol Capsules 0.5 Mcg	33	12.3	12.3
Calcitriol	33	12.1	12.1
Voriconazole Injection	35	12.0	12.0
Quetiapine	283	11.9	11.9
Alcohol	57	11.0	11.0
Clobazam	36	11.0	11.0
Isopropyl Alcohol	49	10.9	10.9
Fluoxetine	95	10.8	10.8
Desvenlafaxine Succinate	39	10.8	10.8
Aripiprazole Oral	59	10.7	10.7
Aripiprazole Orally Disintegrating	59	10.7	10.7
Pyrazinamide	13	10.2	10.3
Sennosides 8.6 Mg Tablets	28	9.9	9.9
Senna	28	9.9	9.9
Olanzapine	137	9.8	9.8
Lamotirigine	90	9.5	9.5
Lamotrigine Extended-Release	90	9.5	9.5
Lamotrigine Chewable Dispersible	90	9.5	9.5
Ganciclovir	13	9.4	9.4
Methadone	53	9.3	9.3
Phenytoin	26	9.3	9.3
Citalopram Hydrobromide	129	9.2	9.3
Mirtazapine	110	9.2	9.2
Ganciclovir Sodium	13	9.1	9.1
Senna Leaf	28	9.0	9.0
Ceftriaxone Sodium	46	9.0	9.0
Voriconazole	36	8.8	8.8
Propranolol Hydrochloride	82	8.6	8.6
Methadone Hydrochloride	12	8.2	8.2
Venlafaxine Hydrochloride	139	8.1	8.1
Clozapine	128	7.8	7.8
Pramipexole	16	7.7	7.7
Ropinirole	16	7.7	7.7
Sennosides	31	7.7	7.7
Dalteparin Sodium	11	7.7	7.7
Bisoprolol Fumarate	135	7.6	7.6
Clindamycin	29	7.6	7.6
Derma Foam Excel Hand Sanitizer	8	7.4	7.4
Ethanol	8	7.4	7.4
Gentamicin	13	7.4	7.4
Fentanyl	94	7.2	7.2
Citalopram	129	7.2	7.2
Phenobarbital	14	7.1	7.2
Valproic Acid	30	7.1	7.1
Candesartan Cilexetil	25	7.1	7.1
Fentanyl Citrate	17	7.0	7.1
Ceftriaxone	31	7.0	7.0
Sodium Bicarbonate	22	7.0	7.0
Sodium Bicarbonate Injection,	22	7.0	7.0
Baclofen	80	7.0	7.0
Propofol	34	6.9	6.9
Cladribine	9	6.9	6.9
Cimetidine	9	6.9	6.9
Escitalopram Oxalate	66	6.8	6.8
Duloxetine	63	6.8	6.8
Midazolam	23	6.8	6.8
Lorazepam	156	6.7	6.7
Fluoxetine Hydrochloride	112	6.7	6.7
Escitslopram	52	6.7	6.7
Doxazosin	25	6.6	6.6
Midazolam Hydrochloride	24	6.6	6.6
Gentamicin Sulfate	14	6.6	6.6
Meropenem	28	6.5	6.5
Lithium	22	6.5	6.5
Lithium Bromatum	22	6.5	6.5
Clindamycin Phosphate	29	6.5	6.5
Glyburide	21	6.4	6.4
Lamotrigine	107	6.2	6.2
Dextrose	11	6.2	6.2
Dextrose Monohydrate	11	6.1	6.1
Carbamazepine	53	5.9	5.9
Prochlorperazine	22	5.9	5.9
Oxazepam	17	5.9	5.9
Diltiazem Hydrochloride Extended-Release Tablets	9	5.8	5.8
Clopidogrel Bisulfate	79	5.8	5.8
Doxazosin Mesylate	28	5.8	5.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	7	5.7	5.7
Bupropion	34	5.7	5.7
Oxycodone And Acetaminophen Tablets	9	5.6	5.6
Tramadol Hydrochloride	28	5.5	5.5
Metformin Hydrochloride Tablets	42	5.5	5.5
Metformin Hydrochloride Extended-Release Tablets	42	5.5	5.5
Metformin Hydrochloride Tablet	42	5.5	5.5
Ramipril	89	5.4	5.4
Amphetamine	6	5.4	5.4
Metformin Hydrochloride	42	5.3	5.3
Paroxetine Hydrochloride Hemihydrate	23	5.1	5.1
Donepezil Hydrochloride	25	5.1	5.1
Paroxetine	23	5.0	5.0
Adrenalinum	28	5.0	5.0
Lansoprazole	117	5.0	5.0
Terbinafine Hydrochloride	6	5.0	5.0
Sertraline	76	4.9	4.9
Memantine	9	4.9	4.9
Memantine Hydrochloride	9	4.9	4.9
Everolimus	32	4.7	4.7
Isoniazid	10	4.6	4.6
Rifampin	9	4.6	4.6
Rocuronium Bromide	7	4.4	4.4
Metformin Hcl	31	4.2	4.2
Aripiprazole	66	4.0	4.0
Cariprazine	5	4.0	4.0
Insulin Aspart	34	3.8	3.8
Lacosamide	19	3.8	3.8
Apixaban	33	3.7	3.7
Timolol	6	3.7	3.7
Medroxyprogesterone Acetate	20	3.0	3.0
Methylphenidate	11	2.8	2.8
Iohexol	3	2.7	2.7
Vortioxetine	6	2.6	2.6
Travoprost	3	2.6	2.6
Orlistat	8	2.3	2.3
Paliperidone	6	1.9	1.9
Brexpiprazole	4	1.8	1.8
Crizotinib	3	1.7	1.7
Buprenorphine	21	1.7	1.7
Tapentadol Hydrochloride	5	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.