OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Cimetidine

1,143 flagged reaction(s) · 49,597 total co-reports · max PRR 329.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Specific Gravity Urine Decreased 20 329.8 330.5 signal
2 Body Tinea 56 241.5 242.9 signal
3 Urine Leukocyte Esterase Positive 53 177.2 178.2 signal
4 Urobilinogen Urine Increased 12 174.0 174.2 signal
5 Creatinine Urine Decreased 10 151.1 151.2 signal
6 Red Cell Distribution Width Decreased 19 93.7 93.9 signal
7 Chronic Kidney Disease-mineral And Bone Disorder 42 89.0 89.3 signal
8 Nitrite Urine Present 16 82.7 82.8 signal
9 Culture Urine Positive 50 80.3 80.7 signal
10 Inhibitory Drug Interaction 56 79.9 80.4 signal
11 Anion Gap Decreased 12 79.3 79.4 signal
12 Rebound Acid Hypersecretion 106 78.4 79.3 signal
13 Androgen Deficiency 12 76.9 77.0 signal
14 Urine Ketone Body Present 43 61.2 61.5 signal
15 Nephrogenic Anaemia 127 61.1 62.0 signal
16 Calcium Deficiency 35 60.4 60.7 signal
17 Infection Susceptibility Increased 57 58.6 59.0 signal
18 Hyperparathyroidism Secondary 66 58.6 59.0 signal
19 Infusion Site Scar 9 45.9 45.9 signal
20 Urine Abnormality 91 45.3 45.8 signal
21 End Stage Renal Disease 348 42.2 43.7 signal
22 Chronic Kidney Disease 1,266 36.8 42.2 signal
23 Band Sensation 20 34.8 34.9 signal
24 White Blood Cells Urine Positive 29 34.5 34.6 signal
25 Red Blood Cells Urine Positive 15 34.4 34.5 signal
26 Aortic Calcification 9 33.9 33.9 signal
27 Monocyte Count Decreased 17 31.1 31.2 signal
28 Aortic Valve Sclerosis 10 30.2 30.2 signal
29 Basophil Count Increased 10 29.5 29.5 signal
30 Primary Sequestrum 12 29.0 29.0 signal
31 Bacterial Test Positive 27 26.8 26.9 signal
32 Leukocyturia 10 26.8 26.9 signal
33 Mean Cell Haemoglobin Increased 20 26.7 26.8 signal
34 Acute Prerenal Failure 14 26.5 26.5 signal
35 Drug Exposure Before Pregnancy 12 26.1 26.1 signal
36 Tetany 21 25.3 25.4 signal
37 Aortic Disorder 9 25.0 25.0 signal
38 Mucosal Erosion 10 24.4 24.4 signal
39 Adenocarcinoma Gastric 10 24.0 24.1 signal
40 Infusion Site Discomfort 11 23.8 23.8 signal
41 Glucose Tolerance Impaired 62 23.3 23.5 signal
42 Secondary Adrenocortical Insufficiency 15 22.2 22.2 signal
43 Haematocrit Increased 22 21.3 21.3 signal
44 Renal Injury 289 21.3 21.9 signal
45 Osteosclerosis 15 21.0 21.0 signal
46 Thyroid Hormones Increased 10 21.0 21.0 signal
47 Lumbar Radiculopathy 11 20.8 20.8 signal
48 Renal Artery Stenosis 12 19.1 19.1 signal
49 Keratitis 26 19.0 19.1 signal
50 Dilatation Atrial 10 18.7 18.7 signal
51 Infusion Site Warmth 10 18.4 18.4 signal
52 Infusion Site Rash 11 17.8 17.8 signal
53 Glucose Urine Present 10 17.4 17.4 signal
54 Hepatic Infection 10 17.4 17.4 signal
55 Peptic Ulcer 25 16.6 16.6 signal
56 Hyperlipidaemia 90 16.6 16.7 signal
57 Lymphocyte Count Decreased 129 16.1 16.3 signal
58 Purpura 64 16.0 16.1 signal
59 Ventricular Hypertrophy 18 15.7 15.7 signal
60 Blood Creatinine Decreased 22 15.5 15.5 signal
61 Vitamin D Deficiency 68 15.4 15.5 signal
62 Diabetic Nephropathy 15 14.9 15.0 signal
63 Atrophy 13 14.6 14.7 signal
64 Tubulointerstitial Nephritis 123 14.5 14.6 signal
65 Multiple Fractures 108 14.4 14.5 signal
66 Red Cell Distribution Width Increased 27 14.3 14.3 signal
67 Chronic Fatigue Syndrome 9 14.3 14.3 signal
68 Protein Urine Present 32 14.2 14.2 signal
69 Cervical Spinal Stenosis 11 14.0 14.0 signal
70 Blood Amylase Increased 11 13.9 14.0 signal
71 Spondylolisthesis 11 13.9 13.9 signal
72 Duodenal Ulcer Haemorrhage 18 13.8 13.8 signal
73 Torsade De Pointes 49 13.7 13.8 signal
74 Mean Cell Volume Increased 16 13.7 13.7 signal
75 Spinal Osteoarthritis 55 13.7 13.8 signal
76 Bone Disorder 114 13.7 13.8 signal
77 Aortic Arteriosclerosis 16 13.7 13.7 signal
78 Mean Cell Haemoglobin Decreased 11 13.2 13.2 signal
79 Colonic Polyp 10 13.1 13.2 signal
80 Anaphylactoid Reaction 24 12.9 12.9 signal
81 Osteolysis 12 12.9 12.9 signal
82 Bone Lesion 21 12.8 12.8 signal
83 Radius Fracture 14 12.8 12.8 signal
84 C-reactive Protein Abnormal 37 12.7 12.8 signal
85 Fibrin D Dimer Increased 20 12.4 12.4 signal
86 Infrequent Bowel Movements 14 12.3 12.4 signal
87 Lumbar Spinal Stenosis 16 12.0 12.0 signal
88 Osteopenia 83 12.0 12.1 signal
89 Intervertebral Disc Degeneration 50 11.8 11.9 signal
90 Impaired Quality Of Life 77 11.8 11.9 signal
91 Blood Ph Decreased 9 11.5 11.5 signal
92 Renal Failure 698 11.5 12.3 signal
93 Renal Tubular Necrosis 51 11.4 11.5 signal
94 Osteoporosis 213 11.4 11.6 signal
95 Neutrophil Count Increased 52 11.1 11.2 signal
96 Poor Quality Sleep 106 10.9 11.0 signal
97 Hyperparathyroidism 10 10.7 10.7 signal
98 Bladder Spasm 9 10.6 10.7 signal
99 Scoliosis 30 10.6 10.7 signal
100 Hypertensive Heart Disease 9 10.5 10.5 signal
101 Supraventricular Extrasystoles 16 10.4 10.4 signal
102 Acute Kidney Injury 717 10.4 11.1 signal
103 Dilatation Ventricular 10 10.3 10.4 signal
104 Gastrooesophageal Reflux Disease 375 10.3 10.7 signal
105 Radiation Pneumonitis 10 10.3 10.3 signal
106 Skin Hypertrophy 13 10.2 10.2 signal
107 Essential Hypertension 12 10.2 10.2 signal
108 Haemoglobin Increased 20 9.8 9.8 signal
109 Left Ventricular Hypertrophy 19 9.7 9.8 signal
110 Excoriation 11 9.4 9.4 signal
111 Cerebral Atrophy 17 9.3 9.4 signal
112 Otitis Media 14 9.3 9.3 signal
113 Foot Fracture 79 9.1 9.2 signal
114 Hyperuricaemia 17 9.1 9.1 signal
115 Nephropathy 38 8.9 8.9 signal
116 Tricuspid Valve Incompetence 32 8.9 8.9 signal
117 Aortic Valve Incompetence 17 8.8 8.8 signal
118 Computerised Tomogram Abnormal 9 8.7 8.7 signal
119 Mastication Disorder 12 8.6 8.7 signal
120 Atrioventricular Block First Degree 17 8.6 8.6 signal
121 Monocyte Count Increased 14 8.5 8.5 signal
122 Mitral Valve Incompetence 43 8.3 8.4 signal
123 Lacunar Infarction 9 8.3 8.3 signal
124 Long Qt Syndrome 9 8.2 8.2 signal
125 Neck Injury 11 8.2 8.2 signal
126 Loose Tooth 12 8.2 8.2 signal
127 Synovial Cyst 17 8.0 8.1 signal
128 Ecchymosis 25 8.0 8.0 signal
129 Renal Failure Chronic 28 7.9 7.9 signal
130 Anxiety Disorder 12 7.8 7.9 signal
131 Ventricular Arrhythmia 13 7.8 7.8 signal
132 Infusion Site Pruritus 11 7.8 7.8 signal
133 Impaired Work Ability 75 7.7 7.7 signal
134 Facet Joint Syndrome 11 7.7 7.7 signal
135 Bone Density Decreased 110 7.6 7.7 signal
136 Blood Urine Present 66 7.6 7.7 signal
137 Fibula Fracture 10 7.6 7.6 signal
138 Carotid Artery Stenosis 12 7.5 7.5 signal
139 Atelectasis 33 7.5 7.5 signal
140 Eosinophil Count Increased 28 7.4 7.4 signal
141 Haemorrhagic Diathesis 12 7.4 7.4 signal
142 Immune Thrombocytopenia 15 7.4 7.4 signal
143 Hiatus Hernia 43 7.3 7.3 signal
144 Prostatitis 10 7.2 7.2 signal
145 Oral Herpes 64 7.2 7.3 signal
146 Exostosis 30 7.2 7.2 signal
147 Wound Dehiscence 11 7.1 7.1 signal
148 Renal Cell Carcinoma 16 7.1 7.1 signal
149 Abdominal Tenderness 16 7.1 7.1 signal
150 Diverticulum 23 7.0 7.0 signal
151 Candidiasis 13 7.0 7.0 signal
152 Hypomagnesaemia 44 7.0 7.0 signal
153 Coma Scale Abnormal 9 6.9 6.9 signal
154 Prothrombin Time Prolonged 19 6.9 6.9 signal
155 Spinal Column Stenosis 15 6.9 6.9 signal
156 Thyroid Function Test Abnormal 13 6.8 6.8 signal
157 Haematocrit Decreased 62 6.8 6.9 signal
158 Intervertebral Disc Protrusion 68 6.8 6.9 signal
159 Gingival Pain 24 6.6 6.6 signal
160 Gastritis Erosive 14 6.6 6.6 signal
161 Flank Pain 28 6.6 6.6 signal
162 Cardiomegaly 37 6.5 6.6 signal
163 Circulatory Collapse 51 6.5 6.6 signal
164 Hand Fracture 21 6.5 6.5 signal
165 Ventricular Tachycardia 49 6.5 6.5 signal
166 Dyslipidaemia 15 6.5 6.5 signal
167 Rotator Cuff Syndrome 38 6.5 6.5 signal
168 Rhinitis Allergic 13 6.4 6.4 signal
169 Hypercholesterolaemia 28 6.4 6.4 signal
170 Cervical Vertebral Fracture 10 6.4 6.4 signal
171 Diastolic Dysfunction 9 6.4 6.4 signal
172 Peripheral Vascular Disorder 15 6.3 6.4 signal
173 Compression Fracture 15 6.3 6.3 signal
174 Electroencephalogram Abnormal 9 6.3 6.3 signal
175 Breath Sounds Abnormal 14 6.2 6.2 signal
176 Disseminated Intravascular Coagulation 40 6.2 6.2 signal
177 Non-cardiac Chest Pain 9 6.2 6.2 signal
178 Dental Caries 31 6.2 6.2 signal
179 Osteoarthritis 119 6.2 6.2 signal
180 Cholecystitis Chronic 19 6.1 6.2 signal
181 Intervertebral Disc Disorder 12 6.1 6.1 signal
182 Polydipsia 11 6.1 6.1 signal
183 Infusion Site Swelling 17 6.1 6.1 signal
184 Anorexia 36 6.0 6.1 signal
185 Facial Bones Fracture 10 6.0 6.0 signal
186 Vitamin B12 Deficiency 11 6.0 6.0 signal
187 Economic Problem 42 6.0 6.0 signal
188 Coronary Artery Disease 82 5.9 5.9 signal
189 Peripheral Arterial Occlusive Disease 11 5.9 5.9 signal
190 Infusion Site Pain 34 5.8 5.9 signal
191 Renal Cyst 21 5.8 5.8 signal
192 Fluid Intake Reduced 13 5.8 5.8 signal
193 Face Injury 10 5.8 5.8 signal
194 Spinal Compression Fracture 22 5.7 5.8 signal
195 Diabetic Neuropathy 13 5.7 5.7 signal
196 Joint Effusion 18 5.7 5.7 signal
197 Oesophageal Ulcer 10 5.7 5.7 signal
198 Toxic Epidermal Necrolysis 39 5.7 5.7 signal
199 Tenderness 27 5.7 5.7 signal
200 Red Blood Cell Count Decreased 74 5.7 5.7 signal
201 Stress Fracture 14 5.7 5.7 signal
202 Bundle Branch Block Left 11 5.7 5.7 signal
203 Purulent Discharge 11 5.6 5.7 signal
204 Poor Peripheral Circulation 11 5.6 5.6 signal
205 Lung Neoplasm 11 5.6 5.6 signal
206 Duodenal Ulcer 18 5.6 5.6 signal
207 Urine Odour Abnormal 15 5.6 5.6 signal
208 Electrocardiogram Qrs Complex Prolonged 13 5.6 5.6 signal
209 Palmar-plantar Erythrodysaesthesia Syndrome 59 5.5 5.6 signal
210 Wrist Fracture 30 5.5 5.5 signal
211 Ventricular Extrasystoles 26 5.5 5.5 signal
212 Blood Urea Increased 42 5.5 5.5 signal
213 Skin Papilloma 10 5.5 5.5 signal
214 Bursitis 30 5.5 5.5 signal
215 Hypokalaemia 111 5.3 5.4 signal
216 Cardiac Murmur 21 5.3 5.3 signal
217 Chronic Sinusitis 9 5.3 5.3 signal
218 Increased Tendency To Bruise 22 5.2 5.2 signal
219 Bundle Branch Block Right 11 5.2 5.2 signal
220 Blood Lactate Dehydrogenase Increased 38 5.2 5.2 signal
221 Post-traumatic Stress Disorder 16 5.2 5.2 signal
222 Neutropenic Sepsis 17 5.2 5.2 signal
223 Pathological Fracture 12 5.2 5.2 signal
224 Hypoalbuminaemia 18 5.2 5.2 signal
225 Rash Maculo-papular 52 5.1 5.2 signal
226 Clavicle Fracture 9 5.1 5.1 signal
227 Pulmonary Tuberculosis 10 5.1 5.1 signal
228 Metastases To Lung 27 5.1 5.1 signal
229 Arteriosclerosis 22 5.1 5.1 signal
230 Back Disorder 38 5.1 5.1 signal
231 Renal Failure Acute 100 5.1 5.1 signal
232 Leukocytosis 42 5.1 5.1 signal
233 Ankle Fracture 36 5.1 5.1 signal
234 Pulse Absent 11 5.1 5.1 signal
235 Cholecystitis Acute 13 5.0 5.0 signal
236 Neutrophil Count Decreased 93 5.0 5.1 signal
237 Ileus 28 5.0 5.0 signal
238 Synovitis 41 5.0 5.0 signal
239 Sinus Bradycardia 22 5.0 5.0 signal
240 Gingival Swelling 10 5.0 5.0 signal
241 Sinus Tachycardia 32 5.0 5.0 signal
242 Oliguria 14 4.9 5.0 signal
243 Left Ventricular Dysfunction 15 4.9 4.9 signal
244 Haemorrhagic Anaemia 10 4.9 4.9 signal
245 Meningitis Aseptic 10 4.9 4.9 signal
246 Skin Disorder 74 4.9 4.9 signal
247 Cyanosis 35 4.9 4.9 signal
248 Cellulitis 112 4.9 4.9 signal
249 Enteritis 14 4.8 4.8 signal
250 Decreased Interest 13 4.8 4.8 signal
251 Pleurisy 13 4.8 4.8 signal
252 Gallbladder Disorder 39 4.8 4.8 signal
253 Hypophosphataemia 16 4.8 4.8 signal
254 Arthritis 170 4.7 4.8 signal
255 Foetal Growth Restriction 13 4.7 4.7 signal
256 Dermatitis Acneiform 13 4.7 4.7 signal
257 Carpal Tunnel Syndrome 30 4.7 4.7 signal
258 Angina Unstable 14 4.7 4.7 signal
259 Inguinal Hernia 13 4.7 4.7 signal
260 Tibia Fracture 10 4.7 4.7 signal
261 Arteriosclerosis Coronary Artery 14 4.6 4.7 signal
262 Pain In Jaw 59 4.6 4.6 signal
263 Cataract 123 4.5 4.6 signal
264 Rales 12 4.5 4.5 signal
265 Diverticulum Intestinal 9 4.5 4.5 signal
266 Blood Thyroid Stimulating Hormone Increased 19 4.5 4.5 signal
267 Blood Alkaline Phosphatase Increased 51 4.5 4.5 signal
268 Gingivitis 11 4.5 4.5 signal
269 Anaphylactic Shock 52 4.5 4.5 signal
270 Alanine Aminotransferase Increased 123 4.4 4.4 signal
271 Haemolytic Anaemia 18 4.4 4.4 signal
272 Osteomyelitis 36 4.4 4.4 signal
273 Pharyngeal Swelling 19 4.4 4.4 signal
274 Gamma-glutamyltransferase Increased 44 4.4 4.4 signal
275 Blood Thyroid Stimulating Hormone Decreased 9 4.3 4.3 signal
276 Hepatic Function Abnormal 73 4.3 4.3 signal
277 Ear Disorder 9 4.3 4.3 signal
278 Femoral Neck Fracture 10 4.3 4.3 signal
279 Dyspepsia 191 4.3 4.3 signal
280 Haemorrhoids 38 4.3 4.3 signal
281 Multi-organ Failure 34 4.3 4.3 signal
282 Benign Prostatic Hyperplasia 10 4.2 4.2 signal
283 Ligament Sprain 19 4.2 4.2 signal
284 Oesophagitis 21 4.2 4.2 signal
285 Cardiac Valve Disease 11 4.2 4.2 signal
286 Major Depression 14 4.2 4.2 signal
287 Stomach Discomfort 10 4.2 4.2 signal
288 Lactic Acidosis 61 4.2 4.2 signal
289 Rib Fracture 39 4.2 4.2 signal
290 Spinal Disorder 18 4.2 4.2 signal
291 Angina Pectoris 54 4.1 4.1 signal
292 Gastritis 49 4.1 4.1 signal
293 Blood Calcium Decreased 21 4.1 4.1 signal
294 Enterococcal Infection 9 4.1 4.1 signal
295 Hyperchlorhydria 11 4.1 4.1 signal
296 Infusion Related Reaction 122 4.1 4.1 signal
297 Faecal Incontinence 9 4.0 4.0 signal
298 Lipase Increased 14 4.0 4.0 signal
299 Pulmonary Fibrosis 35 4.0 4.0 signal
300 Cholelithiasis 60 4.0 4.0 signal
301 Irritable Bowel Syndrome 39 4.0 4.0 signal
302 Choking Sensation 10 4.0 4.0 signal
303 Malnutrition 20 3.9 4.0 signal
304 Tongue Disorder 13 3.9 3.9 signal
305 Electrocardiogram Abnormal 14 3.9 3.9 signal
306 Rash Pustular 13 3.9 3.9 signal
307 Decreased Activity 19 3.9 3.9 signal
308 Metastases To Liver 31 3.9 3.9 signal
309 Oral Candidiasis 23 3.9 3.9 signal
310 Cachexia 9 3.9 3.9 signal
311 Cardiomyopathy 26 3.9 3.9 signal
312 Proteinuria 33 3.8 3.8 signal
313 Chronic Obstructive Pulmonary Disease 91 3.8 3.9 signal
314 Hydronephrosis 13 3.8 3.8 signal
315 Peripheral Coldness 24 3.8 3.8 signal
316 Lymphoedema 12 3.8 3.8 signal
317 Gastrointestinal Pain 19 3.8 3.8 signal
318 Aspartate Aminotransferase Increased 92 3.8 3.8 signal
319 Hypoaesthesia Oral 26 3.8 3.8 signal
320 Osteonecrosis Of Jaw 43 3.8 3.8 signal
321 Multiple Injuries 11 3.8 3.8 signal
322 Hyperventilation 10 3.8 3.8 signal
323 White Blood Cell Count Decreased 186 3.8 3.8 signal
324 Proctalgia 11 3.8 3.8 signal
325 Metastases To Bone 28 3.8 3.8 signal
326 Extrasystoles 12 3.8 3.8 signal
327 Renal Impairment 143 3.7 3.8 signal
328 Anhedonia 45 3.7 3.7 signal
329 Ear Pain 33 3.7 3.7 signal
330 Cardiotoxicity 15 3.7 3.7 signal
331 White Blood Cell Count Increased 65 3.7 3.7 signal
332 Conjunctivitis 31 3.7 3.7 signal
333 Pharyngitis 21 3.7 3.7 signal
334 Respiratory Rate Increased 15 3.7 3.7 signal
335 Lung Infiltration 15 3.7 3.7 signal
336 Joint Injury 36 3.7 3.7 signal
337 Cholecystitis 20 3.7 3.7 signal
338 Toxic Skin Eruption 17 3.7 3.7 signal
339 Gastric Ulcer 32 3.7 3.7 signal
340 Sensation Of Foreign Body 14 3.7 3.7 signal
341 Herpes Zoster 96 3.7 3.7 signal
342 Hepatitis Cholestatic 10 3.7 3.7 signal
343 Bipolar Disorder 18 3.6 3.6 signal
344 International Normalised Ratio Increased 47 3.6 3.6 signal
345 Ulcer Haemorrhage 11 3.6 3.6 signal
346 Cholangitis 10 3.6 3.6 signal
347 Hypercalcaemia 20 3.6 3.6 signal
348 Hepatomegaly 16 3.6 3.6 signal
349 Septic Shock 70 3.6 3.6 signal
350 Frustration Tolerance Decreased 13 3.5 3.5 signal
351 Limb Discomfort 50 3.5 3.6 signal
352 Musculoskeletal Chest Pain 25 3.5 3.5 signal
353 Pancreatitis Acute 36 3.5 3.5 signal
354 Hypertension 342 3.5 3.6 signal
355 Pleural Effusion 98 3.5 3.6 signal
356 Feeling Drunk 12 3.5 3.5 signal
357 Bronchospasm 23 3.5 3.5 signal
358 Diabetes Mellitus 123 3.5 3.6 signal
359 Psychological Trauma 14 3.5 3.5 signal
360 Febrile Neutropenia 106 3.5 3.5 signal
361 Decubitus Ulcer 13 3.5 3.5 signal
362 Groin Pain 14 3.5 3.5 signal
363 Enterocolitis 9 3.5 3.5 signal
364 Lower Limb Fracture 30 3.4 3.5 signal
365 Nocturia 19 3.4 3.4 signal
366 Serotonin Syndrome 30 3.4 3.4 signal
367 C-reactive Protein Increased 57 3.4 3.5 signal
368 Laryngitis 17 3.4 3.4 signal
369 Sinus Disorder 31 3.4 3.4 signal
370 Metastases To Central Nervous System 20 3.4 3.4 signal
371 Contusion 150 3.4 3.5 signal
372 Generalised Erythema 9 3.4 3.4 signal
373 Oral Pain 35 3.4 3.4 signal
374 Blood Bilirubin Increased 42 3.4 3.4 signal
375 Muscle Tightness 25 3.4 3.4 signal
376 Bradycardia 82 3.4 3.4 signal
377 Ejection Fraction Decreased 24 3.4 3.4 signal
378 Vitreous Floaters 15 3.4 3.4 signal
379 Hypoxia 54 3.4 3.4 signal
380 Hypovolaemia 9 3.4 3.4 signal
381 Drug Interaction 244 3.4 3.4 signal
382 Haematoma 40 3.4 3.4 signal
383 Hypocalcaemia 29 3.4 3.4 signal
384 Haematemesis 39 3.4 3.4 signal
385 Apnoea 12 3.4 3.4 signal
386 Platelet Count Increased 20 3.4 3.4 signal
387 Polyp 10 3.3 3.3 signal
388 Tooth Extraction 19 3.3 3.3 signal
389 Blood Albumin Decreased 12 3.3 3.3 signal
390 Gastroenteritis 22 3.3 3.3 signal
391 Bladder Disorder 15 3.3 3.3 signal
392 Depression 344 3.3 3.4 signal
393 Muscle Strain 13 3.3 3.3 signal
394 Platelet Count Decreased 160 3.3 3.3 signal
395 Thyroid Disorder 23 3.3 3.3 signal
396 Rhinitis 12 3.3 3.3 signal
397 Metabolic Acidosis 47 3.3 3.3 signal
398 Myelosuppression 50 3.2 3.2 signal
399 Bone Pain 86 3.2 3.2 signal
400 Facial Pain 13 3.2 3.2 signal
401 Pancytopenia 81 3.2 3.2 signal
402 Musculoskeletal Discomfort 25 3.2 3.2 signal
403 Tachycardia 129 3.2 3.2 signal
404 Tooth Fracture 16 3.2 3.2 signal
405 Chest Pain 268 3.2 3.2 signal
406 Large Intestine Polyp 10 3.2 3.2 signal
407 Acute Coronary Syndrome 12 3.2 3.2 signal
408 Dysuria 53 3.2 3.2 signal
409 Ventricular Fibrillation 16 3.1 3.2 signal
410 Formication 10 3.1 3.1 signal
411 Joint Dislocation 15 3.1 3.1 signal
412 Leukopenia 71 3.1 3.1 signal
413 Upper Gastrointestinal Haemorrhage 24 3.1 3.1 signal
414 Bone Marrow Failure 29 3.1 3.1 signal
415 Seasonal Allergy 20 3.1 3.1 signal
416 Face Oedema 24 3.1 3.1 signal
417 Nerve Compression 13 3.1 3.1 signal
418 Blood Triglycerides Increased 25 3.1 3.1 signal
419 Arrhythmia 67 3.1 3.1 signal
420 Fibromyalgia 34 3.1 3.1 signal
421 Upper Limb Fracture 28 3.1 3.1 signal
422 Depressed Level Of Consciousness 55 3.1 3.1 signal
423 Electrolyte Imbalance 16 3.0 3.1 signal
424 Cardiac Flutter 9 3.0 3.0 signal
425 Body Height Decreased 15 3.0 3.0 signal
426 Panic Reaction 10 3.0 3.0 signal
427 Deformity 13 3.0 3.0 signal
428 Upper Respiratory Tract Infection 64 3.0 3.1 signal
429 Emphysema 14 3.0 3.0 signal
430 Ulcer 22 3.0 3.0 signal
431 Cystitis 44 3.0 3.0 signal
432 Vasculitis 16 3.0 3.0 signal
433 Chromaturia 31 3.0 3.0 signal
434 Temperature Intolerance 14 3.0 3.0 signal
435 Bronchitis 102 3.0 3.0 signal
436 Tooth Abscess 14 3.0 3.0 signal
437 Pneumonia Aspiration 34 3.0 3.0 signal
438 Electrocardiogram Qt Prolonged 49 3.0 3.0 signal
439 Melaena 30 3.0 3.0 signal
440 Sleep Apnoea Syndrome 26 3.0 3.0 signal
441 Injury 96 3.0 3.0 signal
442 Dysarthria 51 3.0 3.0 signal
443 Spinal Fracture 27 3.0 3.0 signal
444 Coordination Abnormal 19 3.0 3.0 signal
445 Feeling Hot 83 3.0 3.0 signal
446 Rhabdomyolysis 56 2.9 3.0 signal
447 Nerve Injury 15 2.9 3.0 signal
448 Oropharyngeal Discomfort 12 2.9 2.9 signal
449 Anaphylactic Reaction 73 2.9 2.9 signal
450 Lymphadenopathy 47 2.9 2.9 signal
451 Neck Pain 74 2.9 2.9 signal
452 Flushing 135 2.9 2.9 signal
453 Emotional Disorder 41 2.9 2.9 signal
454 Cholecystectomy 15 2.9 2.9 signal
455 Body Temperature Increased 27 2.9 2.9 signal
456 Restless Legs Syndrome 24 2.9 2.9 signal
457 Bone Loss 20 2.9 2.9 signal
458 Urinary Incontinence 39 2.9 2.9 signal
459 Obesity 21 2.9 2.9 signal
460 Urticaria 219 2.9 2.9 signal
461 Eye Movement Disorder 9 2.9 2.9 signal
462 Body Temperature Decreased 13 2.9 2.9 signal
463 Myocardial Ischaemia 15 2.9 2.9 signal
464 Acidosis 10 2.9 2.9 signal
465 Coronary Artery Occlusion 18 2.9 2.9 signal
466 Pseudomonas Infection 11 2.8 2.9 signal
467 Pollakiuria 54 2.8 2.9 signal
468 Chest Discomfort 132 2.8 2.9 signal
469 Ascites 38 2.8 2.8 signal
470 Cardiovascular Disorder 33 2.8 2.8 signal
471 Abdominal Distension 134 2.8 2.9 signal
472 Erythema Multiforme 12 2.8 2.8 signal
473 Stomatitis 78 2.8 2.8 signal
474 Visual Acuity Reduced 43 2.8 2.8 signal
475 Scar 22 2.8 2.8 signal
476 Heart Rate Irregular 29 2.8 2.8 signal
477 Multiple Allergies 10 2.8 2.8 signal
478 Blood Magnesium Decreased 11 2.8 2.8 signal
479 Drug Level Increased 21 2.8 2.8 signal
480 Nail Disorder 11 2.8 2.8 signal
481 Gastric Disorder 44 2.8 2.8 signal
482 Dysstasia 37 2.8 2.8 signal
483 Neutropenia 171 2.8 2.8 signal
484 Sciatica 20 2.8 2.8 signal
485 Pericardial Effusion 29 2.8 2.8 signal
486 Myoclonus 15 2.8 2.8 signal
487 Anxiety 358 2.8 2.8 signal
488 Tachypnoea 17 2.8 2.8 signal
489 Supraventricular Tachycardia 12 2.8 2.8 signal
490 Dermatitis Bullous 9 2.7 2.7 signal
491 Abdominal Pain 290 2.7 2.8 signal
492 Sepsis 139 2.7 2.8 signal
493 Agranulocytosis 23 2.7 2.7 signal
494 Local Swelling 22 2.7 2.7 signal
495 Gingival Bleeding 17 2.7 2.7 signal
496 Diabetes Mellitus Inadequate Control 22 2.7 2.7 signal
497 Hereditary Angioedema 13 2.7 2.7 signal
498 Drug Toxicity 17 2.7 2.7 signal
499 Mouth Haemorrhage 9 2.7 2.7 signal
500 Haemoglobin Decreased 126 2.7 2.7 signal
501 Mental Status Changes 34 2.7 2.7 signal
502 Small Intestinal Obstruction 15 2.7 2.7 signal
503 Polyuria 10 2.7 2.7 signal
504 Respiratory Failure 89 2.7 2.7 signal
505 Back Pain 283 2.7 2.7 signal
506 Mass 17 2.7 2.7 signal
507 Erythema 249 2.7 2.7 signal
508 Infusion Site Erythema 10 2.6 2.6 signal
509 Pneumothorax 19 2.6 2.6 signal
510 Hemiplegia 10 2.6 2.6 signal
511 Anaemia 228 2.6 2.7 signal
512 Road Traffic Accident 50 2.6 2.6 signal
513 Hypothyroidism 38 2.6 2.6 signal
514 Cardiogenic Shock 17 2.6 2.6 signal
515 Cold Sweat 21 2.6 2.6 signal
516 Oedema Peripheral 145 2.6 2.6 signal
517 Neuropathy Peripheral 112 2.6 2.6 signal
518 Throat Tightness 32 2.6 2.6 signal
519 Dry Throat 12 2.6 2.6 signal
520 Blood Pressure Decreased 78 2.6 2.6 signal
521 Musculoskeletal Pain 62 2.6 2.6 signal
522 Foot Deformity 13 2.6 2.6 signal
523 Blood Potassium Decreased 35 2.5 2.6 signal
524 Hypoaesthesia 174 2.5 2.6 signal
525 Altered State Of Consciousness 25 2.5 2.5 signal
526 Diverticulitis 32 2.5 2.5 signal
527 Eructation 22 2.5 2.5 signal
528 Type 2 Diabetes Mellitus 39 2.5 2.5 signal
529 Mucosal Inflammation 30 2.5 2.5 signal
530 Acute Myocardial Infarction 34 2.5 2.5 signal
531 Arthropathy 64 2.5 2.5 signal
532 Micturition Urgency 13 2.5 2.5 signal
533 Rash Generalised 30 2.5 2.5 signal
534 Impaired Driving Ability 13 2.5 2.5 signal
535 Affect Lability 11 2.5 2.5 signal
536 Cardiac Failure Congestive 92 2.5 2.5 signal
537 Flatulence 64 2.5 2.5 signal
538 Acute Respiratory Distress Syndrome 20 2.5 2.5 signal
539 Hepatic Steatosis 21 2.5 2.5 signal
540 Insomnia 300 2.5 2.5 signal
541 Atrial Flutter 9 2.5 2.5 signal
542 Eating Disorder 24 2.5 2.5 signal
543 Constipation 242 2.5 2.5 signal
544 Interstitial Lung Disease 54 2.4 2.5 signal
545 Obsessive-compulsive Disorder 9 2.4 2.4 signal
546 Blood Cholesterol Increased 52 2.4 2.5 signal
547 Pneumonitis 30 2.4 2.4 signal
548 Abdominal Pain Lower 28 2.4 2.4 signal
549 Hiccups 9 2.4 2.4 signal
550 Tooth Loss 23 2.4 2.4 signal
551 Abnormal Faeces 9 2.4 2.4 signal
552 Panic Attack 40 2.4 2.4 signal
553 Dehydration 146 2.4 2.4 signal
554 Dyspnoea Exertional 41 2.4 2.4 signal
555 Skin Ulcer 28 2.4 2.4 signal
556 Vomiting 507 2.4 2.4 signal
557 Heart Rate Decreased 38 2.4 2.4 signal
558 Oxygen Saturation Decreased 60 2.4 2.4 signal
559 Haemoptysis 30 2.4 2.4 signal
560 Respiratory Tract Congestion 17 2.3 2.3 signal
561 Rash Papular 24 2.3 2.3 signal
562 Syncope 106 2.3 2.3 signal
563 Gout 19 2.3 2.3 signal
564 Pulmonary Congestion 14 2.3 2.3 signal
565 Hypoglycaemia 51 2.3 2.3 signal
566 Toothache 19 2.3 2.3 signal
567 Gastroenteritis Viral 19 2.3 2.3 signal
568 Libido Decreased 13 2.3 2.3 signal
569 Hyperglycaemia 38 2.3 2.3 signal
570 Dysphagia 99 2.3 2.3 signal
571 Autoimmune Disorder 10 2.3 2.3 signal
572 Stress 75 2.3 2.3 signal
573 Neoplasm 12 2.3 2.3 signal
574 Dizziness Postural 10 2.3 2.3 signal
575 Thrombocytopenia 116 2.3 2.3 signal
576 Hernia 20 2.3 2.3 signal
577 Incontinence 11 2.3 2.3 signal
578 Device Related Infection 16 2.3 2.3 signal
579 Oropharyngeal Pain 96 2.3 2.3 signal
580 Productive Cough 49 2.3 2.3 signal
581 Limb Injury 28 2.3 2.3 signal
582 Fear 28 2.3 2.3 signal
583 Transient Ischaemic Attack 35 2.3 2.3 signal
584 Hyperkalaemia 36 2.3 2.3 signal
585 Throat Irritation 46 2.3 2.3 signal
586 Tendonitis 16 2.3 2.3 signal
587 Nephrolithiasis 47 2.3 2.3 signal
588 Staphylococcal Infection 34 2.3 2.3 signal
589 Night Sweats 33 2.2 2.3 signal
590 Urinary Tract Infection 174 2.2 2.3 signal
591 Haematuria 35 2.2 2.2 signal
592 Bacteraemia 12 2.2 2.2 signal
593 Impaired Gastric Emptying 13 2.2 2.2 signal
594 Systemic Lupus Erythematosus 36 2.2 2.2 signal
595 Convulsion 59 2.2 2.2 signal
596 Back Injury 11 2.2 2.2 signal
597 Impaired Healing 33 2.2 2.2 signal
598 Adrenal Insufficiency 12 2.2 2.2 signal
599 Oedema 54 2.2 2.2 signal
600 Chills 117 2.2 2.2 signal
601 Vaginal Discharge 10 2.2 2.2 signal
602 Lymphopenia 14 2.2 2.2 signal
603 Blood Creatinine Increased 65 2.2 2.2 signal
604 Viral Infection 33 2.2 2.2 signal
605 Neuralgia 24 2.2 2.2 signal
606 Hypotension 198 2.2 2.2 signal
607 Epistaxis 74 2.2 2.2 signal
608 Tooth Infection 13 2.2 2.2 signal
609 Dialysis 14 2.2 2.2 signal
610 Restlessness 36 2.2 2.2 signal
611 Deep Vein Thrombosis 64 2.1 2.2 signal
612 Iron Deficiency Anaemia 9 2.1 2.1 signal
613 Skin Discolouration 45 2.1 2.2 signal
614 Brain Neoplasm 9 2.1 2.1 signal
615 Respiratory Distress 27 2.1 2.1 signal
616 Fistula 11 2.1 2.1 signal
617 Cardio-respiratory Arrest 41 2.1 2.1 signal
618 Eosinophilia 17 2.1 2.1 signal
619 Respiratory Arrest 27 2.1 2.1 signal
620 Hyperbilirubinaemia 10 2.1 2.1 signal
621 Heart Rate Increased 96 2.1 2.1 signal
622 Poor Venous Access 10 2.1 2.1 signal
623 Dermatitis Contact 11 2.1 2.1 signal
624 Peritonitis 20 2.1 2.1 signal
625 Muscle Spasms 177 2.1 2.1 signal
626 Shock 22 2.1 2.1 signal
627 Swelling 90 2.1 2.1 signal
628 Decreased Appetite 223 2.1 2.1 signal
629 Respiratory Tract Infection 25 2.1 2.1 signal
630 Urinary Retention 32 2.1 2.1 signal
631 Weight Fluctuation 10 2.1 2.1 signal
632 Muscular Weakness 109 2.1 2.1 signal
633 Sputum Discoloured 9 2.1 2.1 signal
634 Abdominal Pain Upper 195 2.1 2.1 signal
635 Activities Of Daily Living Impaired 19 2.1 2.1 signal
636 Acute Respiratory Failure 18 2.1 2.1 signal
637 Splenomegaly 11 2.1 2.1 signal
638 Pyrexia 325 2.1 2.1 signal
639 Hemiparesis 16 2.1 2.1 signal
640 Hepatitis 24 2.1 2.1 signal
641 Hip Fracture 30 2.0 2.1 signal
642 Pneumonia 302 2.0 2.1 signal
643 Femur Fracture 29 2.0 2.0 signal
644 Feeling Cold 26 2.0 2.0 signal
645 Multiple Organ Dysfunction Syndrome 26 2.0 2.0 signal
646 Rectal Haemorrhage 40 2.0 2.0 signal
647 Blood Potassium Increased 15 2.0 2.0 signal
648 Disease Progression 109 2.0 2.0 signal
649 Sinusitis 95 2.0 2.0 signal
650 Cerebral Haemorrhage 33 2.0 2.0 signal
651 Lethargy 53 2.0 2.0 signal
652 Renal Disorder 43 2.0 2.0 signal
653 Dyspnoea 518 2.0 2.1 signal
654 Gastrointestinal Haemorrhage 77 2.0 2.0 signal
655 Hot Flush 69 2.0 2.0 signal
656 Hyperhidrosis 118 2.0 2.0 signal
657 Myalgia 155 2.0 2.0 no signal
658 Disorientation 36 2.0 2.0 no signal
659 Liver Disorder 40 2.0 2.0 no signal
660 Coagulopathy 15 2.0 2.0 no signal
661 Prescribed Underdose 18 2.0 2.0 no signal
662 Fungal Infection 30 2.0 2.0 no signal
663 Salivary Hypersecretion 9 2.0 2.0 no signal
664 Nausea 709 2.0 2.0 no signal
665 Pharyngeal Oedema 14 2.0 2.0 no signal
666 Unresponsive To Stimuli 23 2.0 2.0 no signal
667 Retching 19 2.0 2.0 no signal
668 Generalised Oedema 11 2.0 2.0 no signal
669 Sinus Congestion 12 1.9 1.9 no signal
670 Head Injury 28 1.9 1.9 no signal
671 Vertigo 54 1.9 1.9 no signal
672 Helicobacter Infection 9 1.9 1.9 no signal
673 Initial Insomnia 9 1.9 1.9 no signal
674 Cardiac Arrest 73 1.9 1.9 no signal
675 Ear Discomfort 9 1.9 1.9 no signal
676 Drug-induced Liver Injury 27 1.9 1.9 no signal
677 Pulmonary Mass 13 1.9 1.9 no signal
678 Dysgeusia 65 1.9 1.9 no signal
679 Pulmonary Oedema 39 1.9 1.9 no signal
680 Asthenia 327 1.9 1.9 no signal
681 Urosepsis 8 1.9 1.9 no signal
682 Muscle Twitching 20 1.9 1.9 no signal
683 Wheezing 51 1.9 1.9 no signal
684 Rash Macular 30 1.9 1.9 no signal
685 Emotional Distress 104 1.9 1.9 no signal
686 Stevens-johnson Syndrome 19 1.9 1.9 no signal
687 Drug Eruption 15 1.9 1.9 no signal
688 Caesarean Section 10 1.9 1.9 no signal
689 Vision Blurred 116 1.9 1.9 no signal
690 Intentional Drug Misuse 18 1.9 1.9 no signal
691 Taste Disorder 17 1.9 1.9 no signal
692 Hypersensitivity 157 1.9 1.9 no signal
693 Pruritus 320 1.9 1.9 no signal
694 Osteonecrosis 28 1.9 1.9 no signal
695 Breast Pain 9 1.8 1.9 no signal
696 Full Blood Count Decreased 17 1.8 1.8 no signal
697 Nodule 11 1.8 1.8 no signal
698 Cough 235 1.8 1.9 no signal
699 Dry Mouth 68 1.8 1.8 no signal
700 Ataxia 10 1.8 1.8 no signal
701 Dysphonia 49 1.8 1.8 no signal
702 Weight Decreased 234 1.8 1.9 no signal
703 Joint Stiffness 22 1.8 1.8 no signal
704 Musculoskeletal Disorder 16 1.8 1.8 no signal
705 Subdural Haematoma 12 1.8 1.8 no signal
706 Pharmaceutical Product Complaint 22 1.8 1.8 no signal
707 Loss Of Consciousness 107 1.8 1.8 no signal
708 Migraine 79 1.8 1.8 no signal
709 Rash Erythematous 39 1.8 1.8 no signal
710 Basal Cell Carcinoma 13 1.8 1.8 no signal
711 Post Procedural Complication 16 1.8 1.8 no signal
712 Glaucoma 16 1.8 1.8 no signal
713 Palpitations 97 1.8 1.8 no signal
714 Hypophagia 21 1.8 1.8 no signal
715 Myocardial Infarction 145 1.8 1.8 no signal
716 Dermatitis 17 1.8 1.8 no signal
717 Pruritus Generalised 18 1.8 1.8 no signal
718 Lung Disorder 40 1.8 1.8 no signal
719 Haematochezia 45 1.8 1.8 no signal
720 Blood Pressure Systolic Increased 16 1.8 1.8 no signal
721 Fatigue 631 1.8 1.8 no signal
722 Delirium 28 1.8 1.8 no signal
723 Bacterial Infection 15 1.8 1.8 no signal
724 Cyst 10 1.8 1.8 no signal
725 Dizziness 400 1.8 1.8 no signal
726 Injection Site Extravasation 10 1.8 1.8 no signal
727 Swelling Face 52 1.8 1.8 no signal
728 Hypotonia 8 1.7 1.7 no signal
729 Eye Pain 44 1.7 1.7 no signal
730 Abdominal Discomfort 133 1.7 1.8 no signal
731 Muscle Atrophy 10 1.7 1.7 no signal
732 Head Discomfort 14 1.7 1.7 no signal
733 Aphasia 24 1.7 1.7 no signal
734 Abnormal Dreams 22 1.7 1.7 no signal
735 Fall 263 1.7 1.8 no signal
736 Device Occlusion 11 1.7 1.7 no signal
737 Cardiac Disorder 74 1.7 1.7 no signal
738 Paraesthesia 124 1.7 1.7 no signal
739 Localised Infection 19 1.7 1.7 no signal
740 Alopecia 153 1.7 1.7 no signal
741 Tuberculosis 10 1.7 1.7 no signal
742 Cerebral Infarction 19 1.7 1.7 no signal
743 Rhinorrhoea 50 1.7 1.7 no signal
744 Folliculitis 8 1.7 1.7 no signal
745 Diplopia 20 1.7 1.7 no signal
746 Atrial Fibrillation 75 1.7 1.7 no signal
747 Eyelid Oedema 9 1.7 1.7 no signal
748 Madarosis 9 1.7 1.7 no signal
749 Spinal Pain 9 1.7 1.7 no signal
750 Hypersomnia 22 1.7 1.7 no signal
751 Transaminases Increased 17 1.7 1.7 no signal
752 Hyponatraemia 43 1.7 1.7 no signal
753 Blood Pressure Increased 117 1.7 1.7 no signal
754 Contraindicated Product Administered 23 1.7 1.7 no signal
755 Immune System Disorder 10 1.7 1.7 no signal
756 Disturbance In Attention 41 1.7 1.7 no signal
757 Neuroleptic Malignant Syndrome 9 1.7 1.7 no signal
758 Feeding Disorder 15 1.6 1.6 no signal
759 Tremor 125 1.6 1.7 no signal
760 Liver Function Test Abnormal 22 1.6 1.6 no signal
761 Amnesia 49 1.6 1.6 no signal
762 Neurotoxicity 13 1.6 1.6 no signal
763 Blood Pressure Fluctuation 18 1.6 1.6 no signal
764 Increased Appetite 14 1.6 1.6 no signal
765 Liver Injury 18 1.6 1.6 no signal
766 Glomerular Filtration Rate Decreased 9 1.6 1.6 no signal
767 Leukaemia 7 1.6 1.6 no signal
768 Pain 456 1.6 1.7 no signal
769 Hair Texture Abnormal 10 1.6 1.6 no signal
770 Jaundice 20 1.6 1.6 no signal
771 Dyskinesia 30 1.6 1.6 no signal
772 Fracture 14 1.6 1.6 no signal
773 Balance Disorder 64 1.6 1.6 no signal
774 Erectile Dysfunction 19 1.6 1.6 no signal
775 Tardive Dyskinesia 21 1.6 1.6 no signal
776 Hepatitis C 9 1.6 1.6 no signal
777 Encephalopathy 18 1.6 1.6 no signal
778 Coma 35 1.6 1.6 no signal
779 Respiratory Depression 9 1.6 1.6 no signal
780 Laceration 7 1.6 1.6 no signal
781 Weight Increased 163 1.6 1.6 no signal
782 Diarrhoea 468 1.6 1.6 no signal
783 Angioedema 32 1.6 1.6 no signal
784 Ill-defined Disorder 44 1.6 1.6 no signal
785 Hepatotoxicity 16 1.6 1.6 no signal
786 Red Blood Cell Sedimentation Rate Increased 8 1.6 1.6 no signal
787 Arthralgia 298 1.6 1.6 no signal
788 Parkinsonism 7 1.6 1.6 no signal
789 Tooth Disorder 16 1.6 1.6 no signal
790 Rash 309 1.6 1.6 no signal
791 Pulmonary Embolism 68 1.6 1.6 no signal
792 Pain In Extremity 210 1.6 1.6 no signal
793 Skin Reaction 10 1.6 1.6 no signal
794 Agitation 52 1.5 1.5 no signal
795 Drug Hypersensitivity 137 1.5 1.6 no signal
796 Confusional State 114 1.5 1.5 no signal
797 Swollen Tongue 22 1.5 1.5 no signal
798 Feeling Abnormal 168 1.5 1.5 no signal
799 Cardiac Failure 56 1.5 1.5 no signal
800 Photophobia 13 1.5 1.5 no signal
801 Blister 39 1.5 1.5 no signal
802 Paraesthesia Oral 10 1.5 1.5 no signal
803 Drug Exposure During Pregnancy 24 1.5 1.5 no signal
804 Hepatic Failure 21 1.5 1.5 no signal
805 Lip Swelling 23 1.5 1.5 no signal
806 Faeces Discoloured 15 1.5 1.5 no signal
807 Myelodysplastic Syndrome 10 1.5 1.5 no signal
808 Colitis 26 1.5 1.5 no signal
809 Sluggishness 7 1.5 1.5 no signal
810 Rash Pruritic 37 1.5 1.5 no signal
811 Blood Creatine Phosphokinase Increased 20 1.5 1.5 no signal
812 Cholestasis 13 1.5 1.5 no signal
813 Immunodeficiency 10 1.5 1.5 no signal
814 Scratch 7 1.5 1.5 no signal
815 Tinnitus 31 1.5 1.5 no signal
816 Joint Range Of Motion Decreased 9 1.5 1.5 no signal
817 Thirst 12 1.5 1.5 no signal
818 Petechiae 7 1.5 1.5 no signal
819 Generalised Tonic-clonic Seizure 11 1.5 1.5 no signal
820 Gait Disturbance 129 1.5 1.5 no signal
821 Nervous System Disorder 21 1.5 1.5 no signal
822 Cerebrovascular Accident 114 1.5 1.5 no signal
823 Pulmonary Hypertension 14 1.5 1.5 no signal
824 Fluid Retention 34 1.5 1.5 no signal
825 Mouth Ulceration 14 1.5 1.5 no signal
826 Kidney Infection 13 1.5 1.5 no signal
827 Renal Pain 7 1.5 1.5 no signal
828 Pancreatitis 35 1.4 1.5 no signal
829 Cytomegalovirus Infection 11 1.4 1.4 no signal
830 Discomfort 40 1.4 1.4 no signal
831 Mental Impairment 16 1.4 1.4 no signal
832 Suicidal Ideation 60 1.4 1.4 no signal
833 Deafness 17 1.4 1.4 no signal
834 Ovarian Cancer 6 1.4 1.4 no signal
835 Irritability 39 1.4 1.4 no signal
836 Oral Discomfort 9 1.4 1.4 no signal
837 No Therapeutic Response 8 1.4 1.4 no signal
838 Laboratory Test Abnormal 19 1.4 1.4 no signal
839 Drug Administration Error 20 1.4 1.4 no signal
840 Mobility Decreased 46 1.4 1.4 no signal
841 Burning Sensation 45 1.4 1.4 no signal
842 Influenza Like Illness 53 1.4 1.4 no signal
843 Diarrhoea Haemorrhagic 6 1.4 1.4 no signal
844 Thinking Abnormal 12 1.4 1.4 no signal
845 Malaise 281 1.4 1.4 no signal
846 Gynaecomastia 20 1.4 1.4 no signal
847 Paranoia 11 1.4 1.4 no signal
848 Poisoning 8 1.4 1.4 no signal
849 Nasal Congestion 37 1.4 1.4 no signal
850 Posterior Reversible Encephalopathy Syndrome 6 1.4 1.4 no signal
851 Paralysis 9 1.4 1.4 no signal
852 Memory Impairment 86 1.4 1.4 no signal
853 Headache 391 1.4 1.4 no signal
854 Skin Haemorrhage 9 1.4 1.4 no signal
855 Inflammation 32 1.4 1.4 no signal
856 Pallor 17 1.4 1.4 no signal
857 Intestinal Perforation 7 1.4 1.4 no signal
858 Therapy Change 6 1.4 1.4 no signal
859 Malignant Neoplasm Progression 63 1.4 1.4 no signal
860 Rebound Effect 7 1.4 1.4 no signal
861 Somnolence 124 1.4 1.4 no signal
862 Procedural Pain 17 1.3 1.3 no signal
863 Dementia 17 1.3 1.3 no signal
864 Drug Abuse 51 1.3 1.3 no signal
865 Disease Recurrence 29 1.3 1.3 no signal
866 Insurance Issue 9 1.3 1.3 no signal
867 Blood Pressure Abnormal 12 1.3 1.3 no signal
868 Condition Aggravated 182 1.3 1.3 no signal
869 Toxicity To Various Agents 101 1.3 1.3 no signal
870 Respiratory Disorder 18 1.3 1.3 no signal
871 Candida Infection 10 1.3 1.3 no signal
872 Abasia 15 1.3 1.3 no signal
873 Eye Haemorrhage 8 1.3 1.3 no signal
874 Ovarian Cyst 6 1.3 1.3 no signal
875 Quality Of Life Decreased 8 1.3 1.3 no signal
876 Glycosylated Haemoglobin Increased 15 1.3 1.3 no signal
877 Eye Swelling 22 1.3 1.3 no signal
878 Blood Iron Decreased 7 1.3 1.3 no signal
879 Musculoskeletal Stiffness 52 1.3 1.3 no signal
880 Pain Of Skin 16 1.3 1.3 no signal
881 Influenza 66 1.3 1.3 no signal
882 Eyelid Ptosis 6 1.3 1.3 no signal
883 Skin Lesion 16 1.3 1.3 no signal
884 Muscle Rigidity 7 1.3 1.3 no signal
885 Gastric Cancer 15 1.3 1.3 no signal
886 Neoplasm Malignant 39 1.3 1.3 no signal
887 Diabetic Ketoacidosis 14 1.3 1.3 no signal
888 Thrombosis 47 1.3 1.3 no signal
889 Lymphoma 9 1.3 1.3 no signal
890 Nasopharyngitis 107 1.3 1.3 no signal
891 Presyncope 14 1.3 1.3 no signal
892 Spinal Operation 7 1.3 1.3 no signal
893 Metrorrhagia 10 1.3 1.3 no signal
894 Eczema 29 1.3 1.3 no signal
895 Hepatic Enzyme Increased 39 1.3 1.3 no signal
896 Aphonia 8 1.3 1.3 no signal
897 Skeletal Injury 6 1.3 1.3 no signal
898 Hepatic Cytolysis 7 1.3 1.3 no signal
899 Lacrimation Increased 17 1.2 1.2 no signal
900 Blindness Unilateral 8 1.2 1.2 no signal
901 Dystonia 11 1.2 1.2 no signal
902 Ear Infection 15 1.2 1.2 no signal
903 Infection 81 1.2 1.2 no signal
904 Sudden Death 6 1.2 1.2 no signal
905 Intestinal Obstruction 21 1.2 1.2 no signal
906 Breast Cancer Metastatic 6 1.2 1.2 no signal
907 Extrapyramidal Disorder 14 1.2 1.2 no signal
908 Sensory Disturbance 9 1.2 1.2 no signal
909 Hair Colour Changes 7 1.2 1.2 no signal
910 Skin Laceration 6 1.2 1.2 no signal
911 Haemorrhage 58 1.2 1.2 no signal
912 Gastrointestinal Disorder 49 1.2 1.2 no signal
913 Nervousness 29 1.2 1.2 no signal
914 Apathy 8 1.2 1.2 no signal
915 Hypokinesia 8 1.2 1.2 no signal
916 Pelvic Pain 10 1.2 1.2 no signal
917 General Physical Health Deterioration 63 1.2 1.2 no signal
918 Brain Fog 8 1.2 1.2 no signal
919 Rheumatoid Arthritis 62 1.2 1.2 no signal
920 Photosensitivity Reaction 9 1.2 1.2 no signal
921 Skin Infection 6 1.2 1.2 no signal
922 Colon Cancer 8 1.2 1.2 no signal
923 Speech Disorder 28 1.2 1.2 no signal
924 Grand Mal Convulsion 5 1.2 1.2 no signal
925 Intentional Overdose 34 1.2 1.2 no signal
926 Sleep Disorder 37 1.2 1.2 no signal
927 Unevaluable Event 40 1.2 1.2 no signal
928 Mental Disorder 23 1.2 1.2 no signal
929 Suicide Attempt 32 1.2 1.2 no signal
930 Asthma 59 1.2 1.2 no signal
931 Feeling Jittery 10 1.1 1.1 no signal
932 Crying 19 1.1 1.1 no signal
933 Gastric Haemorrhage 6 1.1 1.1 no signal
934 Prescribed Overdose 10 1.1 1.1 no signal
935 Orthostatic Hypotension 9 1.1 1.1 no signal
936 Inflammatory Bowel Disease 5 1.1 1.1 no signal
937 Lung Infection 8 1.1 1.1 no signal
938 Clostridium Difficile Infection 11 1.1 1.1 no signal
939 Polyneuropathy 6 1.1 1.1 no signal
940 Macular Degeneration 6 1.1 1.1 no signal
941 Hallucination, Auditory 8 1.1 1.1 no signal
942 Abscess 8 1.1 1.1 no signal
943 Pneumocystis Jirovecii Pneumonia 5 1.1 1.1 no signal
944 Brain Injury 5 1.1 1.1 no signal
945 Abortion Spontaneous 20 1.1 1.1 no signal
946 Movement Disorder 16 1.1 1.1 no signal
947 Dry Eye 24 1.1 1.1 no signal
948 Cognitive Disorder 23 1.1 1.1 no signal
949 Motor Dysfunction 5 1.1 1.1 no signal
950 Hallucination 37 1.1 1.1 no signal
951 Therapy Non-responder 22 1.1 1.1 no signal
952 Therapeutic Response Unexpected 22 1.1 1.1 no signal
953 Mania 8 1.1 1.1 no signal
954 Euphoric Mood 5 1.1 1.1 no signal
955 Middle Insomnia 9 1.1 1.1 no signal
956 Application Site Irritation 6 1.1 1.1 no signal
957 Hepatic Cirrhosis 9 1.1 1.1 no signal
958 Dermatitis Allergic 6 1.1 1.1 no signal
959 Death 413 1.1 1.1 no signal
960 Transfusion 5 1.0 1.0 no signal
961 Fluid Overload 7 1.0 1.0 no signal
962 Mydriasis 6 1.0 1.0 no signal
963 Blood Glucose Increased 88 1.0 1.0 no signal
964 Choking 9 1.0 1.0 no signal
965 Bedridden 6 1.0 1.0 no signal
966 Blood Glucose Fluctuation 5 1.0 1.0 no signal
967 Delusion 7 1.0 1.0 no signal
968 Peripheral Swelling 69 1.0 1.0 no signal
969 Acute Myeloid Leukaemia 7 1.0 1.0 no signal
970 Nephropathy Toxic 5 1.0 1.0 no signal
971 Multiple Sclerosis Relapse 31 1.0 1.0 no signal
972 Hypertensive Crisis 5 1.0 1.0 no signal
973 Glossodynia 10 1.0 1.0 no signal
974 Sneezing 10 1.0 1.0 no signal
975 Off Label Use 388 1.0 1.0 no signal
976 Hunger 6 1.0 1.0 no signal
977 Eye Infection 5 1.0 1.0 no signal
978 Skin Exfoliation 37 1.0 1.0 no signal
979 Pregnancy 9 1.0 1.0 no signal
980 Treatment Noncompliance 24 1.0 1.0 no signal
981 Blood Glucose Decreased 21 1.0 1.0 no signal
982 Adverse Event 40 1.0 1.0 no signal
983 Nightmare 15 0.9 0.9 no signal
984 Hallucination, Visual 9 0.9 0.9 no signal
985 Neoplasm Progression 15 0.9 0.9 no signal
986 Colitis Ulcerative 19 0.9 0.9 no signal
987 Eye Inflammation 4 0.9 0.9 no signal
988 Drug Effect Decreased 23 0.9 0.9 no signal
989 Covid-19 Pneumonia 5 0.9 0.9 no signal
990 Pericarditis 7 0.9 0.9 no signal
991 Depressed Mood 22 0.9 0.9 no signal
992 Completed Suicide 35 0.9 0.9 no signal
993 Hyperthyroidism 6 0.9 0.9 no signal
994 Intentional Product Misuse 36 0.9 0.9 no signal
995 Pulmonary Arterial Hypertension 6 0.9 0.9 no signal
996 Lung Neoplasm Malignant 17 0.9 0.9 no signal
997 Accidental Overdose 15 0.9 0.9 no signal
998 Illness 41 0.9 0.9 no signal
999 Coeliac Disease 4 0.9 0.9 no signal
1000 Ocular Hyperaemia 19 0.9 0.9 no signal
1001 Drug Withdrawal Syndrome 36 0.9 0.9 no signal
1002 Tendon Rupture 5 0.9 0.9 no signal
1003 Product Physical Issue 8 0.9 0.9 no signal
1004 Drug Ineffective 524 0.9 0.9 no signal
1005 Hypothermia 4 0.9 0.9 no signal
1006 Inappropriate Antidiuretic Hormone Secretion 4 0.9 0.9 no signal
1007 Ischaemic Stroke 7 0.9 0.9 no signal
1008 Drug Reaction With Eosinophilia And Systemic Symptoms 10 0.9 0.9 no signal
1009 Mood Swings 12 0.8 0.8 no signal
1010 Abnormal Behaviour 15 0.8 0.8 no signal
1011 Joint Swelling 45 0.8 0.8 no signal
1012 Sleep Disorder Due To A General Medical Condition 6 0.8 0.8 no signal
1013 Ocular Discomfort 4 0.8 0.8 no signal
1014 Cytokine Release Syndrome 7 0.8 0.8 no signal
1015 Akathisia 5 0.8 0.8 no signal
1016 Visual Impairment 45 0.8 0.8 no signal
1017 Eye Pruritus 12 0.8 0.8 no signal
1018 Drug Dose Omission 61 0.8 0.8 no signal
1019 Application Site Rash 5 0.8 0.8 no signal
1020 Central Nervous System Lesion 5 0.8 0.8 no signal
1021 Seizure 41 0.8 0.8 no signal
1022 Covid-19 63 0.8 0.8 no signal
1023 Withdrawal Syndrome 15 0.8 0.8 no signal
1024 Drug Effect Less Than Expected 5 0.8 0.8 no signal
1025 Anger 12 0.8 0.8 no signal
1026 Drug Effect Incomplete 13 0.8 0.8 no signal
1027 Vaginal Haemorrhage 15 0.8 0.8 no signal
1028 Product Administration Error 7 0.8 0.8 no signal
1029 Incorrect Drug Administration Duration 10 0.8 0.8 no signal
1030 Overdose 75 0.8 0.8 no signal
1031 Surgery 20 0.8 0.8 no signal
1032 Product Prescribing Issue 7 0.8 0.8 no signal
1033 Application Site Erythema 9 0.7 0.7 no signal
1034 Eye Irritation 19 0.7 0.7 no signal
1035 Menstruation Irregular 9 0.7 0.7 no signal
1036 Accident 4 0.7 0.7 no signal
1037 Eye Disorder 11 0.7 0.7 no signal
1038 Breast Cancer Female 9 0.7 0.7 no signal
1039 Multiple Sclerosis 16 0.7 0.7 no signal
1040 Drug Intolerance 32 0.7 0.7 no signal
1041 Product Dose Omission 22 0.7 0.7 no signal
1042 Device Failure 5 0.7 0.7 no signal
1043 Hypoacusis 14 0.7 0.7 no signal
1044 Wrong Technique In Drug Usage Process 12 0.7 0.7 no signal
1045 Blood Count Abnormal 5 0.7 0.7 no signal
1046 Medication Error 18 0.7 0.7 no signal
1047 Blood Glucose Abnormal 6 0.7 0.7 no signal
1048 Product Packaging Issue 3 0.7 0.7 no signal
1049 Muscle Spasticity 4 0.7 0.7 no signal
1050 Ageusia 8 0.7 0.7 no signal
1051 Blindness 13 0.7 0.7 no signal
1052 Dry Skin 42 0.7 0.7 no signal
1053 Abortion Induced 3 0.7 0.7 no signal
1054 Application Site Pain 7 0.7 0.7 no signal
1055 Thrombotic Microangiopathy 3 0.7 0.7 no signal
1056 Knee Operation 3 0.7 0.7 no signal
1057 Injection Site Induration 4 0.7 0.7 no signal
1058 Intentional Product Use Issue 27 0.7 0.7 no signal
1059 Ankylosing Spondylitis 4 0.7 0.7 no signal
1060 Sedation 8 0.7 0.7 no signal
1061 Psychotic Disorder 9 0.7 0.7 no signal
1062 Disability 6 0.7 0.7 no signal
1063 Adverse Reaction 4 0.7 0.7 no signal
1064 Dermatitis Atopic 15 0.7 0.7 no signal
1065 Aggression 15 0.7 0.7 no signal
1066 Product Use In Unapproved Indication 73 0.7 0.7 no signal
1067 Incorrect Product Administration Duration 6 0.6 0.6 no signal
1068 Mood Altered 8 0.6 0.6 no signal
1069 Acute Hepatic Failure 4 0.6 0.6 no signal
1070 Therapy Cessation 15 0.6 0.6 no signal
1071 Therapeutic Product Effect Decreased 13 0.6 0.6 no signal
1072 Injection Site Warmth 6 0.6 0.6 no signal
1073 Prostatic Specific Antigen Increased 4 0.6 0.6 no signal
1074 Lower Respiratory Tract Infection 13 0.6 0.6 no signal
1075 Plasma Cell Myeloma 11 0.6 0.6 no signal
1076 Needle Issue 8 0.6 0.6 no signal
1077 Skin Cancer 6 0.6 0.6 no signal
1078 Product Quality Issue 37 0.6 0.6 no signal
1079 Exposure During Pregnancy 17 0.6 0.6 no signal
1080 Loss Of Personal Independence In Daily Activities 13 0.6 0.6 no signal
1081 Gait Inability 9 0.6 0.6 no signal
1082 Expired Product Administered 9 0.6 0.6 no signal
1083 Product Availability Issue 6 0.6 0.6 no signal
1084 Haemorrhage Intracranial 4 0.6 0.6 no signal
1085 Injection Site Bruising 21 0.6 0.6 no signal
1086 Myocarditis 3 0.6 0.6 no signal
1087 Product Dose Omission Issue 75 0.6 0.6 no signal
1088 Therapy Interrupted 18 0.6 0.6 no signal
1089 Product Substitution Issue 15 0.6 0.6 no signal
1090 Injection Site Erythema 32 0.6 0.6 no signal
1091 Skin Burning Sensation 18 0.6 0.6 no signal
1092 Incorrect Route Of Drug Administration 9 0.5 0.5 no signal
1093 Injection Site Reaction 17 0.5 0.5 no signal
1094 Thyroid Cancer 3 0.5 0.5 no signal
1095 Product Use Issue 46 0.5 0.5 no signal
1096 Injection Site Pruritus 16 0.5 0.5 no signal
1097 Skin Irritation 11 0.5 0.5 no signal
1098 Amenorrhoea 4 0.5 0.5 no signal
1099 Drug Ineffective For Unapproved Indication 13 0.5 0.5 no signal
1100 Premature Baby 7 0.5 0.5 no signal
1101 Treatment Failure 19 0.5 0.5 no signal
1102 Renal Cancer 11 0.5 0.5 no signal
1103 Complication Associated With Device 3 0.5 0.5 no signal
1104 Psoriatic Arthropathy 9 0.5 0.5 no signal
1105 Psoriasis 29 0.5 0.5 no signal
1106 Maternal Exposure During Pregnancy 19 0.5 0.5 no signal
1107 Breast Cancer 20 0.5 0.5 no signal
1108 Inappropriate Schedule Of Drug Administration 15 0.5 0.5 no signal
1109 Injection Site Haematoma 3 0.4 0.4 no signal
1110 Injection Site Haemorrhage 16 0.4 0.4 no signal
1111 Extra Dose Administered 8 0.4 0.4 no signal
1112 Injection Site Swelling 15 0.4 0.4 no signal
1113 Underdose 14 0.4 0.4 no signal
1114 Adverse Drug Reaction 17 0.4 0.4 no signal
1115 Therapeutic Response Decreased 11 0.4 0.4 no signal
1116 Incorrect Dose Administered 41 0.4 0.4 no signal
1117 Drug Dependence 29 0.4 0.4 no signal
1118 Drug Effective For Unapproved Indication 5 0.4 0.4 no signal
1119 Acne 13 0.4 0.4 no signal
1120 Hospitalisation 26 0.4 0.4 no signal
1121 Product Adhesion Issue 6 0.4 0.4 no signal
1122 Injection Site Urticaria 4 0.4 0.4 no signal
1123 Inappropriate Schedule Of Product Administration 28 0.3 0.3 no signal
1124 Menorrhagia 3 0.3 0.3 no signal
1125 Injury Associated With Device 3 0.3 0.3 no signal
1126 Intentional Self-injury 3 0.3 0.3 no signal
1127 Foetal Exposure During Pregnancy 12 0.3 0.3 no signal
1128 Product Preparation Error 3 0.3 0.3 no signal
1129 Wrong Technique In Product Usage Process 29 0.3 0.3 no signal
1130 Pancreatic Carcinoma 4 0.3 0.3 no signal
1131 Device Malfunction 9 0.3 0.3 no signal
1132 Oesophageal Carcinoma 4 0.3 0.3 no signal
1133 Application Site Pruritus 3 0.3 0.3 no signal
1134 Injection Site Rash 4 0.3 0.3 no signal
1135 Injection Site Pain 38 0.3 0.3 no signal
1136 Prostate Cancer 10 0.3 0.3 no signal
1137 Incorrect Dose Administered By Device 3 0.3 0.3 no signal
1138 Bladder Cancer 7 0.3 0.3 no signal
1139 Device Issue 10 0.3 0.3 no signal
1140 No Adverse Event 20 0.2 0.2 no signal
1141 Device Dislocation 4 0.2 0.2 no signal
1142 Dependence 4 0.2 0.2 no signal
1143 Device Difficult To Use 4 0.1 0.1 no signal