Reaction

Glucose Tolerance Impaired reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,799 reports · 372 co-occurring drugs

As of the last recalculation, Glucose Tolerance Impaired appears in 5,799 FAERS reports alongside 372 co-occurring drug terms. The strongest observed disproportionality signal is CIMETIDINE (PRR 23.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Cimetidine	62	23.3	23.5
Lithium Carbonate	86	18.4	18.5
Anakinra	83	18.2	18.3
Olanzapine Pamoate	195	17.7	17.7
Acetylcysteine	46	17.7	17.7
Ziprasidone Mesylate	63	16.0	16.1
Memantine	58	15.4	15.4
Memantine Hydrochloride	58	15.4	15.4
Ziprasidone	73	15.1	15.1
Lanreotide Acetate	28	12.9	12.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	29	12.1	12.2
Diltiazem Hydrochloride Extended-Release Tablets	38	12.1	12.1
Amitriptyline Hydrochloride	49	10.1	10.1
Daspone	23	8.5	8.5
Dapsone Gel, 5%	23	8.5	8.5
Bumetanide	61	8.4	8.4
Olanzapine	239	8.3	8.3
Dapsone	24	8.1	8.1
Octreotide Acetate	66	7.8	7.8
Divalproex Sodium	95	7.4	7.4
Diltiazem Hydrochloride	67	7.0	7.0
Abacavir Sulfate	19	7.0	7.0
Clobetasol Propionate Ointment Usp, 0.05%	20	7.0	7.0
Clobetasol Propionate	20	7.0	7.0
Indapamide	34	6.8	6.9
Dolutegravir Sodium	17	6.8	6.8
Quetiapine	339	6.6	6.7
Aripiprazole	217	6.6	6.6
Buspirone Hydrochloride	20	6.5	6.5
Losartan Potassium And Hydrochlorothiazide	21	6.5	6.5
Clonidine	88	6.2	6.3
Raltegravir	28	6.1	6.1
Valsartan And Hydrochlorothiazide	23	6.1	6.1
Ezetimibe	124	6.0	6.1
Sodium Oxybate	109	6.0	6.0
Risperidone	216	6.0	6.0
Alendronate Sodium	164	6.0	6.0
Naltrexone Hydrochloride And Bupropion Hydrochloride	14	5.9	5.9
Methylprednisolone Acetate	13	5.8	5.8
Tizanidine Hydrochloride	29	5.8	5.8
Darunavir	24	5.7	5.7
Ezetimibe And Simvastatin	24	5.7	5.7
Relugolix	37	5.7	5.7
Lidocaine Hydrochloride	93	5.6	5.6
Atorvastatin Calcium	366	5.6	5.6
Lopinavir And Ritonavir	21	5.6	5.6
Vitamin E	46	5.3	5.3
Gemfibrozil	22	5.2	5.2
Colchicine	38	5.2	5.2
Lithium	36	5.2	5.2
Lithium Bromatum	36	5.2	5.2
Armodafinil	30	5.1	5.1
Mometasone	26	5.1	5.1
Icosapent Ethyl	12	5.1	5.1
Mometasone Furoate	58	5.0	5.0
Modafinil	45	5.0	5.0
Ciclesonide	19	5.0	5.0
Salmeterol Xinafoate	12	5.0	5.0
Metoroprolol Tartrate	89	4.9	4.9
Amlodipine Besylate And Valsartan	15	4.9	4.9
Amlodipine Besylate	191	4.8	4.8
Methocarbamol	30	4.8	4.8
Mycophenolate Mofetil	174	4.7	4.7
Mycophenolate Mofetil Hydrochloride	174	4.7	4.7
Ascorbic Acid	30	4.6	4.7
Isosorbide Dinitrate	25	4.6	4.6
Zidovudine	17	4.6	4.6
Lisinopril And Hydrochlorothiazide	13	4.6	4.6
Montelukast	105	4.6	4.6
Efavirenz	14	4.5	4.5
Methocarbamol Tablets	21	4.5	4.5
Lidicaine	61	4.5	4.5
Burn Relief	61	4.5	4.5
Lidocaine Hydrochloride And Epinephrine	61	4.5	4.5
Captopril	12	4.5	4.5
Inclisiran	10	4.5	4.5
Lidocaine, Menthol	61	4.5	4.5
Cyclobenzaprine Hydrochloride	11	4.4	4.4
Cetirizine Hcl	11	4.3	4.3
Itraconazole	14	4.3	4.3
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	42	4.3	4.3
Magnesium	96	4.2	4.2
Lidocaine Hydrochloride And Epinephrine Bitartrate	62	4.2	4.2
Vitamin C	106	4.2	4.2
Valsartan	121	4.2	4.2
Lidocaine 4%	63	4.2	4.2
Carisoprodol	22	4.2	4.2
Fish Oil	103	4.1	4.1
Rosuvastatin	229	4.1	4.1
Bupropion Hydrochloride	112	4.1	4.1
Alpelisib	10	4.1	4.1
Clonazepam	179	4.1	4.1
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	56	4.0	4.1
Azelastine	20	4.0	4.0
Lidocaine	64	4.0	4.0
Lamivudine	34	4.0	4.0
Progesterone	25	3.9	3.9
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	45	3.9	3.9
Nilotinib	32	3.9	3.9
Trazodone Hydrochloride	17	3.9	3.9
Valsartan Oral	58	3.9	3.9
Dornase Alfa	21	3.9	3.9
Venlafaxine Hydrochloride	139	3.8	3.8
Ritonavir	31	3.8	3.8
Fluticasone Propionate Nasal	32	3.8	3.8
Pancrelipase	40	3.7	3.7
Paliperidone	24	3.7	3.7
Zolpidem Tartrate	137	3.7	3.7
Mirtazapine	93	3.7	3.7
Desloratadine	11	3.7	3.7
Metformin Hcl	56	3.7	3.7
Lisinopril And Hydrochlorothiazide Tablets	8	3.7	3.7
Metformin Hydrochloride Tablets	58	3.7	3.7
Metformin Hydrochloride Extended-Release Tablets	58	3.7	3.7
Metformin Hydrochloride Tablet	58	3.7	3.7
Methylprednisolone Sodium Succinate	47	3.7	3.7
Hydrochlorothiazide	145	3.6	3.7
Enalapril Maleate	25	3.6	3.6
Metformin Hydrochloride	59	3.6	3.6
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	18	3.6	3.6
Fenofibrate	35	3.6	3.6
Cyclobenzaprine	49	3.5	3.5
Tretinoin	8	3.5	3.5
Meperidine Hydrochloride	9	3.5	3.5
Meclizine Hydrochloride	19	3.5	3.5
Metoprolol	240	3.5	3.5
Metoprolol Tartrate	257	3.5	3.5
Elexacaftor, Tezacaftor, And Ivacaftor	12	3.5	3.5
Escitalopram	132	3.4	3.4
Metoprolol Succinate Er Tablets	59	3.4	3.4
Conjugated Estrogens	55	3.4	3.4
Montelukast Sodium	114	3.4	3.4
Chlorthalidone	11	3.4	3.4
Spironolactone	130	3.4	3.4
Estrogens, Conjugated	55	3.3	3.3
Fluticasone Propionate	119	3.3	3.3
Albuterol	110	3.3	3.3
Sertraline Hydrochloride	108	3.3	3.3
Human Immunoglobulin G	19	3.3	3.3
Meclizine	15	3.3	3.3
Liothyronine Sodium	8	3.3	3.3
Promethazine Hydrochloride	17	3.3	3.3
Budesonide And Formoterol Fumarate Dihydrate	88	3.3	3.3
Prednisolone	162	3.3	3.3
Prednisolone Oral	162	3.3	3.3
Prednisolone Oral Solution	162	3.3	3.3
Oxybutynin Chloride	8	3.3	3.3
Lurasidone Hydrochloride	19	3.3	3.3
Timolol Maleate	9	3.3	3.3
Temazepam	34	3.3	3.3
Somatropin	66	3.2	3.3
Ibuprofen And Diphenhydramine Citrate	21	3.2	3.2
Etonogestrel And Ethinyl Estradiol	20	3.2	3.2
Aripiprazole Oral	37	3.2	3.2
Aripiprazole Orally Disintegrating	37	3.2	3.2
Metformin	309	3.2	3.2
Hydroxychloroquine Sulfate	81	3.2	3.2
Levothyroxine Sodium	273	3.2	3.2
Simvastatin	218	3.2	3.2
Losartan	153	3.2	3.2
Doxepin	9	3.2	3.2
Instalax Polyethylene Glycol 3350	11	3.2	3.2
Febuxostat Tablets 40 Mg	9	3.2	3.2
Febuxostat Tablets 80 Mg	9	3.2	3.2
Duloxetine Hydrochloride	163	3.2	3.2
Metoprolol Succinate	76	3.2	3.2
Zinc Gluconate	23	3.2	3.2
Meclizine Hcl 12.5Mg	12	3.2	3.2
Meclizine Hcl 25Mg	12	3.2	3.2
Meclizine Hcl 12.5 Mg	12	3.2	3.2
Meclizine Hcl 25 Mg	12	3.2	3.2
Torsemide	29	3.2	3.2
Atorvastatin Calcium, Film Coated	61	3.1	3.1
Ergocalciferol	323	3.1	3.1
Polyethylene Glycol 400	11	3.1	3.1
Ciprofloxacin Hydrochloride And Hydrocortisone	18	3.1	3.1
Eszopiclone	22	3.1	3.1
Paroxetine Hydrochloride	78	3.1	3.1
Metformin Er 500 Mg	252	3.1	3.1
Metformin Er 750 Mg	252	3.1	3.1
Nitroglycerin	46	3.1	3.1
Lovastatin	22	3.1	3.1
Niraparib	19	3.1	3.1
Rosuvastatin Calcium	24	3.1	3.1
Atenolol	112	3.1	3.1
Metoprolol Tartrate Injection	158	3.0	3.0
Sacubitril And Valsartan	97	3.0	3.0
Candesartan Cilexetil	22	3.0	3.0
Pregabalin	222	3.0	3.0
Atazanavir	12	3.0	3.0
Fluoxetine Hydrochloride	105	3.0	3.0
Lumacaftor And Ivacaftor	7	2.9	2.9
Losartan Potassium	64	2.9	2.9
Methylphenidate Hydrochloride	48	2.9	2.9
Psyllium Husk	8	2.9	2.9
Olmesartan Medoxomil	29	2.9	2.9
Rabeprazole Sodium	22	2.9	2.9
Diphenhydramine Hcl	9	2.9	2.9
Amiodarone Hydrochloride	9	2.9	2.9
Fluticasone Propionate And Salmeterol Xinafoate	48	2.9	2.9
Calcium	117	2.9	2.9
Doxepin Hydrochloride	10	2.8	2.8
Terazosin Hydrochloride	7	2.8	2.8
Brimonidine Tartrate	14	2.8	2.8
Haloperidol	19	2.8	2.8
Estradiol	67	2.8	2.8
Paliperidone Palmitate	25	2.8	2.8
Estradiol Gel 0.1%	35	2.8	2.8
Estradiol Transdermal	35	2.8	2.8
Dicyclomine Hydrochloride	11	2.8	2.8
Zinc	19	2.8	2.8
Haloperidol Lactate	19	2.8	2.8
Esomeprazole Magnesium	176	2.8	2.8
Zinc Chloride	19	2.8	2.8
Pantoprazole Sodium	112	2.7	2.7
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	23	2.7	2.7
Enalapril	42	2.7	2.7
Amlodipine Besylate And Benazepril Hydrochloride	7	2.7	2.7
Cyclosporine	83	2.7	2.7
Ketoconazole	13	2.7	2.7
Goserelin	10	2.7	2.7
Lubiprostone	7	2.7	2.7
Lisinopril	221	2.7	2.7
Biotin	23	2.7	2.7
Duloxetine	51	2.6	2.6
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	15	2.6	2.6
Naproxen Sodium, Pseudoephedrine Hydrochloride	15	2.6	2.6
Mepolizumab	36	2.6	2.6
Aspirin	375	2.6	2.6
Aspirin 325 Mg	357	2.6	2.6
Aspirin 81 Mg	357	2.6	2.6
Brexpiprazole	12	2.6	2.6
Albuterol Sulfate	210	2.6	2.6
Guaifenesin	22	2.6	2.6
Ticagrelor	23	2.6	2.6
Bicalutamide	11	2.6	2.6
Tiotropium Bromide Inhalation Spray	8	2.6	2.6
Celecoxib	93	2.6	2.6
Topiramate	65	2.5	2.5
Dapagliflozin	22	2.5	2.5
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	7	2.5	2.5
Loratadine Oral	34	2.5	2.5
Asenapine Maleate	6	2.5	2.5
Omeprazole Magnesium	299	2.5	2.5
Rizatriptan Benzoate	7	2.5	2.5
Rifampin	10	2.5	2.5
Triamcinolone Acetonide Ointment Usp, 0.05%	16	2.5	2.5
Alprazolam	139	2.5	2.5
Mycophenilic Acid	14	2.4	2.4
Amlodipine	179	2.4	2.4
Omalizumab	57	2.4	2.4
Testosterone Cypionate	6	2.4	2.4
Tizanidine	16	2.4	2.4
Nevirapine	6	2.4	2.4
Timolol	8	2.4	2.4
Extended Phenytoin Sodium	11	2.4	2.4
Pravastatin Sodium	13	2.4	2.4
Clozapine	81	2.3	2.3
Warfarin Sodium	30	2.3	2.3
Tacrolimus Ointment 0.1%	80	2.3	2.3
Oxcarbazepine	21	2.3	2.3
Tacrolimus Extended-Release Capsules	80	2.3	2.3
Doxazosin	18	2.3	2.3
Gabapentin	229	2.3	2.3
Posaconazole Delayed-Release	7	2.3	2.3
Lisdexamfetamine Dimesylate	21	2.3	2.3
Conjugated Estrogens And Medroxyprogesterone Acetate	15	2.3	2.3
Tacrolimus	98	2.3	2.3
Carvedilol	84	2.2	2.2
Cladribine	6	2.2	2.2
Loperamide Hcl	8	2.2	2.2
Triamcinolone Acetonide	19	2.2	2.2
Tenofovir Disoproxil Fumarate	20	2.2	2.2
Linaclotide	16	2.2	2.2
Febuxostat	10	2.1	2.1
Cetirizine Hydrochloride Allergy	18	2.1	2.1
Cetirizine Hydrochloride Tablets	18	2.1	2.1
Diclofenac Potassium, Film Coated	5	2.1	2.1
Diclofenac Potassium Tablets	5	2.1	2.1
Loratadine	63	2.1	2.1
Loperamide Hydrochloride Oral	6	2.1	2.1
Pitavastatin Calcium	6	2.1	2.1
Tobramycin Solution	7	2.1	2.1
Multivitamin	29	2.1	2.1
Orlistat	15	2.1	2.1
Tobramycin Sulfate	7	2.0	2.0
Apremilast	82	2.0	2.0
Umeclidinium	5	2.0	2.0
Diclofenac Potassium	6	2.0	2.0
Canakinumab	6	2.0	2.0
Rimegepant Sulfate	7	2.0	2.0
Sumatriptan	21	2.0	2.0
Loratadine Tablet	29	1.9	1.9
Agalsidase Beta	5	1.9	1.9
Latanoprost	27	1.9	1.9
Cariprazine	5	1.9	1.9
Pioglitazone	23	1.9	1.9
Carboxymethylcellulose Sodium	5	1.9	1.9
Everolimus	27	1.9	1.9
Fluticasone Propionate And Salmeterol	22	1.9	1.9
Desvenlafaxine Succinate	14	1.9	1.9
Oral Semaglutide	38	1.9	1.9
Glimepiride	20	1.8	1.8
Oxybutynin	15	1.8	1.8
Abiraterone Acetate	21	1.8	1.8
Naproxen Sodium Tablet	27	1.8	1.8
Medroxyprogesterone Acetate	25	1.8	1.8
Ocrelizumab	31	1.8	1.8
Tobramycin	12	1.8	1.8
Interferon Beta-1A	95	1.8	1.8
Acetaminophen And Codeine	6	1.8	1.8
Naltrexone	15	1.7	1.7
Amphetamine	4	1.7	1.7
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	20	1.7	1.7
Ozanimod Hydrochloride	4	1.7	1.7
Budesonide, Glycopyrrolate, And Formoterol Fumarate	5	1.7	1.7
Acetaminophen, Aspirin, And Caffeine	10	1.7	1.7
Acetaminophen, Aspirin (Nsaid) And Caffeine	8	1.7	1.7
Tiotropium Bromide	64	1.7	1.7
Secukinumab	75	1.7	1.7
Risankizumab-Rzaa	38	1.7	1.7
Suvorexant	6	1.7	1.7
Atomoxetine Hydrochloride	11	1.7	1.7
Ruxolitinib	33	1.7	1.7
Evolocumab	74	1.6	1.6
Levocetirizine Dihydrochloride	11	1.6	1.6
Empagliflozin	30	1.6	1.6
Fluticasone Furoate And Vilanterol Trifenatate	16	1.6	1.6
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	4	1.6	1.6
Abaloparatide	13	1.6	1.6
Abiraterone	6	1.6	1.6
Emtricitabine And Tenofovir Disoproxil Fumarate	20	1.6	1.6
Alirocumab	11	1.6	1.6
Vilazodone Hydrochloride	4	1.6	1.6
Interferon Beta-1B	8	1.5	1.5
Methylphenidate	12	1.5	1.5
Fexofenadine Hydrochloride	9	1.5	1.5
Cortisone Acetate	5	1.5	1.5
Benralizumab	8	1.4	1.4
Dofetilide	4	1.4	1.4
Upadacitinib	30	1.3	1.3
Pegvaliase-Pqpz	3	1.3	1.3
Ofatumumab	12	1.3	1.3
Umeclidinium Bromide And Vilanterol Trifenatate	6	1.3	1.3
Vortioxetine	6	1.3	1.3
Fremanezumab-Vfrm	4	1.3	1.3
Tofacitinib	64	1.2	1.2
Belimumab	11	1.2	1.2
Varenicline Tartrate	27	1.2	1.2
Bosutinib	3	1.2	1.2
Brivaracetam	3	1.2	1.2
Avapritinib	4	1.2	1.2
Leuprolide Acetate	25	1.2	1.2
Bimatoprost	9	1.1	1.1
Lifitegrast	5	1.1	1.1
Ravulizumab	4	1.1	1.1
Dalfampridine	21	1.1	1.1
Hydrocodone Bitartrate	12	1.0	1.0
Ranibizumab	7	0.9	0.9
Diroximel Fumarate	3	0.9	0.9
Abemaciclib	5	0.9	0.9
Dimethyl Fumarate	30	0.9	0.9
Sarilumab	6	0.8	0.8
Romosozumab-Aqqg	3	0.8	0.8
Minoxidil Foam 5% (Womens)	7	0.8	0.8
Valbenazine	5	0.7	0.7
Minoxidil	7	0.6	0.6
Tirzepatide	25	0.6	0.6
Etonogestrel	7	0.5	0.5
Dupilumab	65	0.5	0.5
Copper	4	0.3	0.3
Pimavanserin Tartrate	5	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.