OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Infusion Site Discomfort reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,009 reports · 45 co-occurring drugs

As of the last recalculation, Infusion Site Discomfort appears in 1,009 FAERS reports alongside 45 co-occurring drug terms. The strongest observed disproportionality signal is HUMAN IMMUNOGLOBULIN G (PRR 112.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Human Immunoglobulin G101112.1112.7
Treprostinil29568.168.3
Ketoprofen4167.267.4
Diphenhydramine Hydrochloride Capsule, Liquid Filled4949.749.8
Adrenalinum8847.847.9
Amitriptyline Hydrochloride3947.747.8
Lidocaine Hydrochloride9736.636.7
Diphenhydramine9734.935.0
Epinephrine9834.134.1
Macitentan10334.134.1
Sodium Chloride Tablet10833.833.8
Sodium Chloride Tablets10833.833.8
Dimenhydrinate1733.533.5
Sodium Chloride10931.831.8
Sildenafil8030.930.9
Lidocaine7930.230.3
Sildenafil Powder,4929.829.8
Infliximab-Dyyb3928.628.6
Riociguat4328.428.4
Lidocaine, Menthol6026.526.5
Lidicaine5825.925.9
Burn Relief5825.925.9
Lidocaine Hydrochloride And Epinephrine5825.825.9
0Xygen5825.725.7
Oxygen5825.725.7
Cimetidine1123.823.8
Lidocaine Hydrochloride And Epinephrine Bitartrate5823.723.8
Lidocaine 4%5823.223.3
Diphenhydramine Hydrochloride15823.123.1
Tranexamic Acid921.121.1
Buspirone Hydrochloride1120.820.8
Eptinezumab-Jjmr920.620.6
Azelastine1719.819.9
Tadalafil8819.819.8
Sildenafil Citrate10719.319.3
Agalsidase Beta818.018.0
Clonidine4217.617.6
Butalbital, Acetaminophen, And Caffeine917.617.6
Selexipag2016.316.3
Epoprostenol914.314.3
Ambrisentan7212.712.7
Umeclidinium511.611.6
Bendamustine Hydrochloride58.78.7
Rimegepant Sulfate58.28.2
Budesonide, Glycopyrrolate, And Formoterol Fumarate47.97.9

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.