OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Febuxostat

1,136 flagged reaction(s) · 62,738 total co-reports · max PRR 1,074.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Red Blood Cell Sedimentation Rate 129 1,074.3 1,082.7 signal
2 Congenital Diaphragmatic Anomaly 10 477.3 477.6 signal
3 Cytomegalovirus Nephritis 11 332.9 333.1 signal
4 Adult T-cell Lymphoma/leukaemia Recurrent 9 301.8 302.0 signal
5 Granuloma Skin 145 267.4 269.7 signal
6 Enthesopathy 247 234.0 237.5 signal
7 Splenic Necrosis 13 224.1 224.2 signal
8 Hyperkinetic Heart Syndrome 9 223.4 223.5 signal
9 Polycystic Liver Disease 13 173.5 173.6 signal
10 Gouty Tophus 26 164.6 164.9 signal
11 Blood Parathyroid Hormone Decreased 165 156.7 158.2 signal
12 Tenosynovitis 249 124.6 126.5 signal
13 Osteoma 13 97.2 97.3 signal
14 Panniculitis 165 92.4 93.4 signal
15 Alanine Aminotransferase Abnormal 142 91.3 92.1 signal
16 Splenic Cyst 14 89.1 89.2 signal
17 Haemoglobin Urine Present 13 85.4 85.4 signal
18 Rheumatoid Nodule 164 78.7 79.5 signal
19 Respiratory Tract Haemorrhage 33 73.5 73.7 signal
20 Activated Partial Thromboplastin Time Abnormal 13 70.1 70.2 signal
21 Metastases To Soft Tissue 13 65.8 65.9 signal
22 Rheumatoid Lung 46 63.1 63.2 signal
23 Blood Uric Acid Decreased 20 53.8 53.9 signal
24 Gout 698 50.9 53.0 signal
25 Splenic Lesion 14 49.8 49.8 signal
26 C-reactive Protein Abnormal 239 48.7 49.4 signal
27 Lordosis 13 48.2 48.2 signal
28 Skin Necrosis 172 43.0 43.4 signal
29 Drug Tolerance Decreased 89 41.3 41.5 signal
30 Tongue Disorder 229 40.8 41.4 signal
31 Dyspnoea Paroxysmal Nocturnal 20 35.1 35.1 signal
32 Gouty Arthritis 21 34.1 34.1 signal
33 Nephrogenic Anaemia 109 30.0 30.2 signal
34 Blood Uric Acid Abnormal 9 28.6 28.7 signal
35 Hyperuricaemia 89 27.9 28.0 signal
36 Prothrombin Time Abnormal 15 27.9 27.9 signal
37 Blood Uric Acid Increased 124 27.6 27.8 signal
38 Hyperparathyroidism Secondary 54 27.4 27.5 signal
39 Pneumonia Haemophilus 10 26.3 26.4 signal
40 Urinary Sediment Present 13 26.0 26.0 signal
41 Tonsil Cancer 16 25.3 25.3 signal
42 Cerebral Artery Thrombosis 10 24.8 24.8 signal
43 Orthostatic Intolerance 13 23.3 23.4 signal
44 Thalamus Haemorrhage 16 23.3 23.3 signal
45 Granuloma 61 22.6 22.7 signal
46 Red Blood Cells Urine Positive 16 21.1 21.1 signal
47 Hypercalcaemia 201 20.8 21.1 signal
48 Systemic Infection 27 20.7 20.8 signal
49 Cardiac Failure Chronic 66 19.8 19.9 signal
50 Transformation To Acute Myeloid Leukaemia 10 19.4 19.4 signal
51 Drug Monitoring Procedure Incorrectly Performed 10 19.1 19.1 signal
52 Tumour Lysis Syndrome 129 18.8 19.0 signal
53 Red Blood Cell Abnormality 14 18.5 18.5 signal
54 Tendonitis 220 18.0 18.3 signal
55 Folate Deficiency 16 17.8 17.8 signal
56 Chronic Kidney Disease-mineral And Bone Disorder 15 17.8 17.8 signal
57 Superinfection Bacterial 11 17.7 17.7 signal
58 Synovitis 241 17.0 17.3 signal
59 Hypoparathyroidism 10 16.7 16.7 signal
60 Blister Infected 10 16.2 16.2 signal
61 Red Blood Cell Sedimentation Rate Increased 140 16.1 16.2 signal
62 Differentiation Syndrome 9 16.0 16.0 signal
63 Prostatic Specific Antigen Abnormal 13 15.8 15.8 signal
64 Drug Eruption 215 15.5 15.7 signal
65 Drug Tolerance 59 14.8 14.8 signal
66 Coronavirus Test Positive 12 14.7 14.7 signal
67 Haematocrit Abnormal 14 14.4 14.4 signal
68 Fear Of Injection 79 14.4 14.5 signal
69 Osteochondrosis 13 14.1 14.1 signal
70 Basal Cell Carcinoma 172 14.0 14.1 signal
71 Ulcer 174 13.9 14.0 signal
72 Fulminant Type 1 Diabetes Mellitus 11 13.7 13.7 signal
73 Periodontitis 23 13.6 13.7 signal
74 Orthopnoea 33 13.1 13.2 signal
75 Blood Bilirubin Abnormal 13 13.0 13.0 signal
76 Cardiac Amyloidosis 11 12.9 12.9 signal
77 Physical Deconditioning 25 12.7 12.7 signal
78 Upper Respiratory Tract Inflammation 12 12.6 12.6 signal
79 Cardiac Failure Acute 66 12.6 12.7 signal
80 Ureterolithiasis 10 12.1 12.1 signal
81 Rhonchi 13 11.9 11.9 signal
82 Lung Opacity 24 11.8 11.8 signal
83 Prerenal Failure 13 11.8 11.8 signal
84 End Stage Renal Disease 170 11.7 11.8 signal
85 Rebound Acid Hypersecretion 28 11.6 11.6 signal
86 Small Intestinal Perforation 17 11.5 11.5 signal
87 Hyperphosphataemia 19 11.4 11.4 signal
88 Brain Natriuretic Peptide Increased 27 11.1 11.1 signal
89 N-terminal Prohormone Brain Natriuretic Peptide Increased 12 10.9 10.9 signal
90 Rubber Sensitivity 13 10.8 10.8 signal
91 Mean Cell Haemoglobin Increased 14 10.7 10.7 signal
92 Cerebellar Infarction 14 10.5 10.5 signal
93 Mesothelioma 10 10.5 10.5 signal
94 Glomerulonephritis Rapidly Progressive 9 10.4 10.5 signal
95 White Blood Cells Urine Positive 15 10.2 10.2 signal
96 Skin Ulcer 204 10.0 10.1 signal
97 Diabetic Nephropathy 17 9.7 9.7 signal
98 Haematoma Muscle 9 9.7 9.7 signal
99 Seborrhoeic Keratosis 11 9.5 9.5 signal
100 C-reactive Protein Increased 267 9.3 9.4 signal
101 Cytomegalovirus Test Positive 13 9.3 9.3 signal
102 Immune-mediated Hepatic Disorder 14 9.3 9.3 signal
103 Contraindicated Product Administered 218 9.2 9.3 signal
104 Anaemia Macrocytic 15 9.0 9.0 signal
105 Hypoproteinaemia 13 8.9 8.9 signal
106 Aortic Arteriosclerosis 18 8.8 8.8 signal
107 Bile Duct Stone 22 8.8 8.8 signal
108 Normocytic Anaemia 10 8.8 8.8 signal
109 Aspartate Aminotransferase Increased 365 8.7 8.9 signal
110 Osteolysis 14 8.6 8.6 signal
111 Aortic Valve Stenosis 12 8.5 8.5 signal
112 Anti-neutrophil Cytoplasmic Antibody Positive Vasculitis 16 8.3 8.3 signal
113 Anticoagulation Drug Level Above Therapeutic 10 8.2 8.2 signal
114 Chronic Fatigue Syndrome 9 8.2 8.2 signal
115 Hyperkalaemia 226 8.2 8.3 signal
116 Haemorrhage Subcutaneous 23 8.2 8.2 signal
117 Neoplasm Skin 10 8.1 8.1 signal
118 Generalised Erythema 37 8.1 8.1 signal
119 Blood Blister 20 8.1 8.1 signal
120 Hypopituitarism 11 8.0 8.0 signal
121 Chronic Kidney Disease 482 8.0 8.2 signal
122 Glomerular Filtration Rate Decreased 76 7.9 8.0 signal
123 Blood Creatinine Increased 409 7.9 8.1 signal
124 Renal Impairment 518 7.8 8.1 signal
125 Diverticulum Intestinal Haemorrhagic 14 7.8 7.8 signal
126 Hypoalbuminaemia 46 7.6 7.6 signal
127 Linear Iga Disease 10 7.6 7.6 signal
128 Embolic Stroke 21 7.6 7.6 signal
129 Marasmus 9 7.6 7.6 signal
130 Tubulointerstitial Nephritis 110 7.4 7.5 signal
131 Dermatitis Exfoliative Generalised 20 7.4 7.4 signal
132 Psoriatic Arthropathy 233 7.3 7.4 signal
133 Alanine Aminotransferase Increased 355 7.3 7.4 signal
134 Azotaemia 23 7.3 7.3 signal
135 Immune-mediated Lung Disease 10 7.2 7.2 signal
136 Cytokine Release Syndrome 109 7.2 7.3 signal
137 Skin Erosion 18 7.1 7.1 signal
138 Acute Kidney Injury 857 7.1 7.4 signal
139 Immune-mediated Hepatitis 11 7.1 7.1 signal
140 Hepatic Cyst 19 7.1 7.1 signal
141 Benign Prostatic Hyperplasia 29 7.1 7.1 signal
142 Ventricular Hypokinesia 18 7.1 7.1 signal
143 Umbilical Hernia 26 7.0 7.0 signal
144 Dyslipidaemia 28 7.0 7.0 signal
145 Haemothorax 16 7.0 7.0 signal
146 Mixed Liver Injury 16 6.9 7.0 signal
147 Pneumonia Bacterial 50 6.9 6.9 signal
148 International Normalised Ratio Abnormal 19 6.9 6.9 signal
149 Calciphylaxis 10 6.9 6.9 signal
150 Lacunar Infarction 13 6.9 6.9 signal
151 Blood Pressure Systolic Increased 106 6.8 6.9 signal
152 Loss Of Personal Independence In Daily Activities 257 6.8 6.9 signal
153 Pemphigoid 39 6.7 6.7 signal
154 Lower Gastrointestinal Haemorrhage 39 6.6 6.7 signal
155 Cardiac Failure 418 6.6 6.7 signal
156 Hepatic Mass 10 6.6 6.6 signal
157 Blood Phosphorus Increased 14 6.5 6.5 signal
158 Blood Urea Increased 86 6.5 6.5 signal
159 Right Ventricular Failure 36 6.4 6.5 signal
160 Mean Cell Volume Increased 13 6.4 6.4 signal
161 Fibrin D Dimer Increased 18 6.4 6.4 signal
162 Small Intestinal Haemorrhage 10 6.3 6.3 signal
163 Cholangitis 30 6.1 6.2 signal
164 Concomitant Disease Aggravated 30 6.1 6.1 signal
165 Cytomegalovirus Colitis 11 6.1 6.1 signal
166 Disseminated Intravascular Coagulation 68 6.1 6.1 signal
167 Renal Tubular Necrosis 47 6.0 6.1 signal
168 Venous Thrombosis Limb 10 6.0 6.0 signal
169 Troponin Increased 36 6.0 6.0 signal
170 Acute Myeloid Leukaemia Recurrent 10 5.9 5.9 signal
171 Left Ventricular Failure 16 5.9 5.9 signal
172 Cholestatic Liver Injury 10 5.9 5.9 signal
173 Cardiac Dysfunction 17 5.9 5.9 signal
174 Renal Function Test Abnormal 21 5.8 5.8 signal
175 Immune-mediated Enterocolitis 16 5.7 5.7 signal
176 Hepatic Function Abnormal 166 5.7 5.7 signal
177 Covid-19 Pneumonia 53 5.6 5.6 signal
178 Joint Injury 95 5.6 5.6 signal
179 Pneumocystis Jirovecii Pneumonia 44 5.6 5.6 signal
180 Pneumonia Fungal 17 5.5 5.5 signal
181 Enterocolitis 25 5.5 5.5 signal
182 Labelled Drug-drug Interaction Medication Error 39 5.5 5.5 signal
183 Osteomyelitis 79 5.5 5.5 signal
184 Cytomegalovirus Viraemia 19 5.5 5.5 signal
185 Polyomavirus-associated Nephropathy 10 5.4 5.4 signal
186 Myelofibrosis 13 5.4 5.4 signal
187 Pulmonary Alveolar Haemorrhage 24 5.4 5.4 signal
188 Neutrophil Count Decreased 173 5.4 5.4 signal
189 Atrial Tachycardia 9 5.4 5.4 signal
190 Haemoglobin Abnormal 27 5.3 5.3 signal
191 Infusion Related Reaction 275 5.3 5.3 signal
192 International Normalised Ratio Decreased 17 5.3 5.3 signal
193 Inflammation 212 5.2 5.3 signal
194 Rash Pruritic 222 5.2 5.3 signal
195 Blood Creatinine Abnormal 14 5.1 5.2 signal
196 Musculoskeletal Disorder 78 5.1 5.2 signal
197 Distributive Shock 9 5.1 5.1 signal
198 Faecaloma 22 5.1 5.1 signal
199 Iron Deficiency Anaemia 37 5.1 5.1 signal
200 Thyroiditis 12 5.1 5.1 signal
201 Chronic Gastritis 9 5.1 5.1 signal
202 Immune Thrombocytopenia 18 5.1 5.1 signal
203 Atrial Flutter 32 5.0 5.0 signal
204 Creatinine Renal Clearance Decreased 16 5.0 5.0 signal
205 Cerebral Infarction 97 5.0 5.0 signal
206 Toxic Epidermal Necrolysis 59 4.9 5.0 signal
207 Peripheral Arterial Occlusive Disease 16 4.9 4.9 signal
208 Odynophagia 23 4.9 4.9 signal
209 Haemorrhoidal Haemorrhage 19 4.9 4.9 signal
210 Essential Hypertension 10 4.9 4.9 signal
211 Tumour Haemorrhage 11 4.9 4.9 signal
212 Procedural Haemorrhage 15 4.8 4.8 signal
213 Amylase Increased 14 4.8 4.8 signal
214 Hypocalcaemia 72 4.8 4.8 signal
215 Hypokalaemia 175 4.8 4.9 signal
216 Hypoxic-ischaemic Encephalopathy 10 4.8 4.8 signal
217 Acute Myeloid Leukaemia 59 4.8 4.8 signal
218 Lymphocyte Count Decreased 67 4.8 4.8 signal
219 Acute Myocardial Infarction 112 4.8 4.8 signal
220 Aplasia Pure Red Cell 13 4.8 4.8 signal
221 Escherichia Urinary Tract Infection 16 4.8 4.8 signal
222 Blood Potassium Abnormal 10 4.7 4.7 signal
223 Gastric Ulcer Haemorrhage 21 4.7 4.8 signal
224 Adrenal Insufficiency 45 4.7 4.8 signal
225 Interstitial Lung Disease 181 4.7 4.8 signal
226 Cholecystitis Acute 21 4.7 4.7 signal
227 Hypercapnia 11 4.6 4.6 signal
228 Gastric Perforation 10 4.6 4.6 signal
229 Potentiating Drug Interaction 12 4.6 4.6 signal
230 Bacteraemia 43 4.6 4.6 signal
231 Blood Potassium Increased 59 4.6 4.6 signal
232 Intraventricular Haemorrhage 9 4.6 4.6 signal
233 Sputum Discoloured 34 4.5 4.5 signal
234 Non-small Cell Lung Cancer 17 4.5 4.5 signal
235 Shock Haemorrhagic 29 4.5 4.5 signal
236 Cardiac Tamponade 17 4.5 4.5 signal
237 Erythema Multiforme 33 4.5 4.5 signal
238 Renal Failure 465 4.4 4.5 signal
239 Hepatic Lesion 15 4.4 4.4 signal
240 Anuria 30 4.4 4.4 signal
241 Blood Lactate Dehydrogenase Increased 55 4.4 4.4 signal
242 Melaena 76 4.3 4.4 signal
243 Pulmonary Arterial Hypertension 50 4.3 4.3 signal
244 Febrile Neutropenia 227 4.3 4.4 signal
245 Gastritis Erosive 16 4.3 4.3 signal
246 Protein Urine Present 17 4.3 4.3 signal
247 Carotid Artery Stenosis 12 4.3 4.3 signal
248 Nephropathy 32 4.3 4.3 signal
249 Hepatitis Acute 22 4.3 4.3 signal
250 Immune Effector Cell-associated Neurotoxicity Syndrome 19 4.3 4.3 signal
251 Ileus Paralytic 15 4.3 4.3 signal
252 Haemorrhagic Anaemia 15 4.2 4.2 signal
253 Hypovolaemic Shock 16 4.2 4.2 signal
254 Dermatitis Bullous 24 4.2 4.2 signal
255 Platelet Count Abnormal 20 4.2 4.2 signal
256 Lung Adenocarcinoma 10 4.2 4.2 signal
257 Spinal Osteoarthritis 29 4.1 4.1 signal
258 Pulmonary Toxicity 23 4.1 4.1 signal
259 Stevens-johnson Syndrome 73 4.1 4.1 signal
260 Therapy Non-responder 146 4.1 4.2 signal
261 Splenomegaly 38 4.1 4.1 signal
262 Staphylococcal Sepsis 16 4.1 4.1 signal
263 Oliguria 20 4.1 4.1 signal
264 Cytomegalovirus Infection 53 4.0 4.0 signal
265 Pulmonary Function Test Decreased 14 4.0 4.0 signal
266 Coronavirus Infection 21 4.0 4.0 signal
267 Chronic Lymphocytic Leukaemia 15 4.0 4.0 signal
268 Duodenal Ulcer Haemorrhage 9 4.0 4.0 signal
269 Haemoglobin Increased 14 3.9 3.9 signal
270 Myoclonus 37 3.9 3.9 signal
271 Flank Pain 29 3.9 3.9 signal
272 Anaemia 588 3.9 4.0 signal
273 Nephrotic Syndrome 21 3.9 3.9 signal
274 Pleural Effusion 186 3.9 3.9 signal
275 Angina Unstable 20 3.8 3.8 signal
276 Cytomegalovirus Infection Reactivation 13 3.8 3.8 signal
277 Rhabdomyolysis 126 3.8 3.8 signal
278 Pneumonia Aspiration 75 3.8 3.8 signal
279 Duodenal Ulcer 21 3.8 3.8 signal
280 Coronary Artery Stenosis 15 3.7 3.8 signal
281 Altered State Of Consciousness 64 3.7 3.8 signal
282 Supraventricular Extrasystoles 10 3.7 3.7 signal
283 Stress Cardiomyopathy 17 3.7 3.7 signal
284 Pulmonary Fibrosis 56 3.7 3.7 signal
285 Platelet Count Decreased 311 3.7 3.7 signal
286 Appetite Disorder 19 3.7 3.7 signal
287 Dyspnoea Exertional 109 3.7 3.7 signal
288 Myelodysplastic Syndrome 42 3.7 3.7 signal
289 Faecal Calprotectin Increased 9 3.6 3.6 signal
290 Large Intestine Polyp 20 3.6 3.6 signal
291 Hypomagnesaemia 40 3.6 3.6 signal
292 Hepatocellular Carcinoma 22 3.6 3.6 signal
293 General Physical Health Deterioration 331 3.6 3.7 signal
294 Eosinophilic Pneumonia 9 3.6 3.6 signal
295 Organising Pneumonia 14 3.6 3.6 signal
296 Drug Intolerance 273 3.6 3.6 signal
297 Hepatitis B Reactivation 9 3.6 3.6 signal
298 Oedema Peripheral 346 3.6 3.6 signal
299 Drug-induced Liver Injury 87 3.6 3.6 signal
300 Upper Gastrointestinal Haemorrhage 47 3.5 3.5 signal
301 Haemophagocytic Lymphohistiocytosis 20 3.5 3.5 signal
302 Acute Coronary Syndrome 23 3.5 3.5 signal
303 Lymphocyte Count Increased 9 3.5 3.5 signal
304 Diffuse Large B-cell Lymphoma 21 3.5 3.5 signal
305 Muscle Haemorrhage 11 3.5 3.5 signal
306 Lactic Acidosis 88 3.5 3.5 signal
307 Spinal Compression Fracture 23 3.5 3.5 signal
308 Cystitis Haemorrhagic 11 3.5 3.5 signal
309 Infective Pulmonary Exacerbation Of Cystic Fibrosis 15 3.4 3.5 signal
310 Myelosuppression 93 3.4 3.5 signal
311 Blood Creatine Phosphokinase Increased 79 3.4 3.4 signal
312 Iron Deficiency 12 3.4 3.4 signal
313 Cardiac Failure Congestive 218 3.4 3.4 signal
314 Humerus Fracture 13 3.4 3.4 signal
315 Atelectasis 26 3.4 3.4 signal
316 Haematocrit Decreased 53 3.3 3.4 signal
317 Prothrombin Time Prolonged 16 3.3 3.3 signal
318 Pulmonary Congestion 35 3.3 3.3 signal
319 Drug Reaction With Eosinophilia And Systemic Symptoms 67 3.3 3.3 signal
320 Hypernatraemia 13 3.3 3.3 signal
321 Disease Complication 12 3.3 3.3 signal
322 Thrombotic Microangiopathy 25 3.3 3.3 signal
323 Hiccups 21 3.2 3.2 signal
324 Angina Pectoris 74 3.2 3.2 signal
325 Activated Partial Thromboplastin Time Prolonged 13 3.2 3.2 signal
326 Haemolytic Anaemia 23 3.2 3.2 signal
327 Ascites 75 3.2 3.2 signal
328 Femoral Neck Fracture 13 3.2 3.2 signal
329 Enteritis 16 3.2 3.2 signal
330 Urine Output Decreased 22 3.2 3.2 signal
331 Hypoxia 88 3.2 3.2 signal
332 Hyperlipidaemia 30 3.2 3.2 signal
333 Renal Injury 75 3.1 3.2 signal
334 Bone Lesion 9 3.1 3.1 signal
335 Kidney Transplant Rejection 12 3.1 3.1 signal
336 Rhinitis Allergic 11 3.1 3.1 signal
337 Ventricular Tachycardia 41 3.1 3.1 signal
338 Multiple Organ Dysfunction Syndrome 69 3.1 3.1 signal
339 Subarachnoid Haemorrhage 25 3.1 3.1 signal
340 Proteinuria 46 3.1 3.1 signal
341 Toxic Encephalopathy 12 3.1 3.1 signal
342 Pancreatitis Acute 54 3.1 3.1 signal
343 Torsade De Pointes 19 3.0 3.0 signal
344 Hypertriglyceridaemia 14 3.0 3.0 signal
345 Atrial Fibrillation 234 3.0 3.1 signal
346 Haematochezia 132 3.0 3.0 signal
347 Febrile Bone Marrow Aplasia 10 3.0 3.0 signal
348 Pancytopenia 133 3.0 3.0 signal
349 Toxic Skin Eruption 24 3.0 3.0 signal
350 Rosacea 11 3.0 3.0 signal
351 Cholecystitis 28 3.0 3.0 signal
352 Abscess Limb 10 3.0 3.0 signal
353 Bundle Branch Block Left 10 3.0 3.0 signal
354 Hypogammaglobulinaemia 15 2.9 3.0 signal
355 Type 1 Diabetes Mellitus 14 2.9 2.9 signal
356 Treatment Failure 191 2.9 3.0 signal
357 Blood Triglycerides Increased 41 2.9 2.9 signal
358 Therapeutic Product Effect Decreased 102 2.9 2.9 signal
359 Pulmonary Hypertension 48 2.9 2.9 signal
360 Hypervolaemia 11 2.9 2.9 signal
361 Dizziness Postural 22 2.9 2.9 signal
362 Transfusion 24 2.9 2.9 signal
363 Increased Tendency To Bruise 21 2.9 2.9 signal
364 Haematoma 59 2.9 2.9 signal
365 Device Related Infection 35 2.9 2.9 signal
366 Renal Cyst 18 2.9 2.9 signal
367 Scoliosis 14 2.8 2.8 signal
368 Blood Creatine Increased 10 2.8 2.8 signal
369 Eosinophilia 39 2.8 2.8 signal
370 Lipase Increased 17 2.8 2.8 signal
371 Haematuria 76 2.8 2.8 signal
372 Low Density Lipoprotein Increased 17 2.8 2.8 signal
373 Pyelonephritis 19 2.8 2.8 signal
374 Red Blood Cell Count Decreased 63 2.8 2.8 signal
375 Coronary Artery Disease 67 2.8 2.8 signal
376 Atrioventricular Block 17 2.8 2.8 signal
377 Ecchymosis 15 2.8 2.8 signal
378 Pulmonary Haemorrhage 17 2.7 2.7 signal
379 Electrolyte Imbalance 25 2.7 2.7 signal
380 Pericardial Effusion 50 2.7 2.7 signal
381 Therapeutic Response Decreased 131 2.7 2.8 signal
382 Sars-cov-2 Test Positive 29 2.7 2.7 signal
383 Peripheral Swelling 332 2.7 2.8 signal
384 Cellulitis 109 2.7 2.7 signal
385 Aortic Dissection 9 2.7 2.7 signal
386 Arthritis Infective 10 2.7 2.7 signal
387 Electrocardiogram Abnormal 17 2.7 2.7 signal
388 Prescribed Underdose 43 2.7 2.7 signal
389 Gastric Disorder 75 2.7 2.7 signal
390 Tricuspid Valve Incompetence 17 2.7 2.7 signal
391 Hepatic Enzyme Increased 146 2.7 2.7 signal
392 Pneumothorax 34 2.7 2.7 signal
393 Hydronephrosis 16 2.7 2.7 signal
394 Oedema 116 2.7 2.7 signal
395 Septic Shock 92 2.7 2.7 signal
396 Congestive Cardiomyopathy 9 2.7 2.7 signal
397 Pallor 58 2.7 2.7 signal
398 Arteriosclerosis 20 2.7 2.7 signal
399 Liver Function Test Abnormal 62 2.7 2.7 signal
400 Drug Level Increased 35 2.7 2.7 signal
401 Aortic Valve Incompetence 9 2.7 2.7 signal
402 Left Ventricular Hypertrophy 9 2.6 2.6 signal
403 Haemoglobin Decreased 216 2.6 2.7 signal
404 Atrioventricular Block Complete 14 2.6 2.6 signal
405 Colitis Ischaemic 14 2.6 2.6 signal
406 White Blood Cell Count Decreased 226 2.6 2.6 signal
407 Hiatus Hernia 27 2.6 2.6 signal
408 Myopathy 18 2.6 2.6 signal
409 Rash Vesicular 10 2.6 2.6 signal
410 Hypothyroidism 66 2.6 2.6 signal
411 Fluid Retention 105 2.6 2.6 signal
412 Atrioventricular Block First Degree 9 2.6 2.6 signal
413 Agranulocytosis 38 2.6 2.6 signal
414 Eyelid Oedema 24 2.6 2.6 signal
415 Eosinophil Count Increased 17 2.6 2.6 signal
416 Cerebral Haemorrhage 73 2.6 2.6 signal
417 Renal Disorder 95 2.6 2.6 signal
418 Mitral Valve Incompetence 23 2.6 2.6 signal
419 Liver Disorder 90 2.6 2.6 signal
420 Ileus 25 2.6 2.6 signal
421 White Blood Cell Count Increased 78 2.6 2.6 signal
422 International Normalised Ratio Increased 58 2.5 2.5 signal
423 Body Temperature Decreased 20 2.5 2.5 signal
424 Haemoptysis 56 2.5 2.5 signal
425 Metabolic Acidosis 63 2.5 2.5 signal
426 Decreased Appetite 460 2.5 2.5 signal
427 Acute Respiratory Failure 38 2.5 2.5 signal
428 Lumbar Vertebral Fracture 9 2.5 2.5 signal
429 Hyponatraemia 111 2.5 2.5 signal
430 Dialysis 28 2.5 2.5 signal
431 Acidosis 15 2.5 2.5 signal
432 Neurotoxicity 34 2.5 2.5 signal
433 Left Ventricular Dysfunction 13 2.5 2.5 signal
434 Epistaxis 146 2.5 2.5 signal
435 Tendon Rupture 24 2.4 2.4 signal
436 Gamma-glutamyltransferase Increased 43 2.4 2.4 signal
437 Faeces Soft 14 2.4 2.4 signal
438 Arrhythmia 92 2.4 2.4 signal
439 Blood Pressure Decreased 128 2.4 2.4 signal
440 Uveitis 26 2.4 2.4 signal
441 Renal Failure Chronic 15 2.4 2.4 signal
442 Gastroenteritis 28 2.4 2.4 signal
443 Hypophosphataemia 14 2.4 2.4 signal
444 Myasthenia Gravis 15 2.4 2.4 signal
445 Serum Ferritin Increased 10 2.4 2.4 signal
446 Arthritis 150 2.4 2.4 signal
447 Rheumatoid Arthritis 215 2.4 2.4 signal
448 Arthropathy 106 2.4 2.4 signal
449 Therapeutic Product Effect Incomplete 134 2.4 2.4 signal
450 Orthostatic Hypotension 33 2.4 2.4 signal
451 Pseudomonas Infection 16 2.4 2.4 signal
452 Subdural Haematoma 27 2.4 2.4 signal
453 Joint Effusion 13 2.4 2.4 signal
454 Colon Cancer 28 2.4 2.4 signal
455 Bradycardia 99 2.3 2.4 signal
456 Anal Abscess 10 2.3 2.3 signal
457 Tachypnoea 25 2.3 2.3 signal
458 Rash 799 2.3 2.4 signal
459 Poor Venous Access 19 2.3 2.3 signal
460 Platelet Count Increased 24 2.3 2.3 signal
461 Gastrointestinal Haemorrhage 154 2.3 2.3 signal
462 Ventricular Extrasystoles 19 2.3 2.3 signal
463 Cardiogenic Shock 26 2.3 2.3 signal
464 Hepatitis B 11 2.3 2.3 signal
465 Bronchopulmonary Aspergillosis 14 2.3 2.3 signal
466 Rash Maculo-papular 40 2.3 2.3 signal
467 Squamous Cell Carcinoma 17 2.3 2.3 signal
468 Respiratory Failure 131 2.3 2.3 signal
469 Metastases To Lymph Nodes 12 2.3 2.3 signal
470 Drug Hypersensitivity 347 2.3 2.3 signal
471 Myositis 16 2.2 2.2 signal
472 Lymphopenia 25 2.2 2.2 signal
473 Dehydration 234 2.2 2.2 signal
474 Pollakiuria 73 2.2 2.2 signal
475 Lymphadenopathy 62 2.2 2.2 signal
476 Sepsis 194 2.2 2.2 signal
477 Blood Magnesium Decreased 15 2.2 2.2 signal
478 Gastric Ulcer 33 2.2 2.2 signal
479 Productive Cough 82 2.2 2.2 signal
480 Pneumonia 557 2.2 2.2 signal
481 Aplastic Anaemia 9 2.2 2.2 signal
482 Rash Generalised 45 2.2 2.2 signal
483 Post Procedural Haemorrhage 20 2.2 2.2 signal
484 Hyperglycaemia 62 2.1 2.2 signal
485 Generalised Oedema 21 2.1 2.1 signal
486 Hypertensive Crisis 19 2.1 2.1 signal
487 Glucose Tolerance Impaired 10 2.1 2.1 signal
488 Cardiomegaly 21 2.1 2.1 signal
489 Cardiomyopathy 25 2.1 2.1 signal
490 Product Prescribing Error 40 2.1 2.1 signal
491 Pleurisy 10 2.1 2.1 signal
492 Hepatic Steatosis 31 2.1 2.1 signal
493 Erythema 338 2.1 2.1 signal
494 Intestinal Ischaemia 9 2.1 2.1 no signal
495 Liver Function Test Increased 35 2.1 2.1 signal
496 Circulatory Collapse 28 2.1 2.1 signal
497 Vasculitis 19 2.1 2.1 signal
498 Thirst 29 2.0 2.1 signal
499 Drug Interaction 258 2.0 2.1 signal
500 Fluid Overload 24 2.0 2.0 signal
501 Coagulopathy 27 2.0 2.0 signal
502 Malnutrition 18 2.0 2.0 signal
503 Nephropathy Toxic 18 2.0 2.0 signal
504 Gingival Bleeding 22 2.0 2.0 signal
505 Pyrexia 556 2.0 2.1 signal
506 Hepatic Encephalopathy 15 2.0 2.0 signal
507 Dermatitis Allergic 20 2.0 2.0 signal
508 Musculoskeletal Stiffness 140 2.0 2.0 signal
509 Thrombocytopenia 178 2.0 2.0 signal
510 Encephalitis 11 2.0 2.0 signal
511 Cytopenia 19 2.0 2.0 signal
512 Hepatic Failure 48 2.0 2.0 signal
513 Joint Swelling 191 2.0 2.0 no signal
514 Large Intestine Perforation 11 2.0 2.0 no signal
515 Acute Respiratory Distress Syndrome 28 2.0 2.0 no signal
516 Abdominal Pain Lower 40 2.0 2.0 no signal
517 Hypertension 334 2.0 2.0 no signal
518 Hypercholesterolaemia 15 2.0 2.0 no signal
519 Mobility Decreased 112 2.0 2.0 no signal
520 Urinary Retention 52 2.0 2.0 no signal
521 Neutrophil Count Increased 16 2.0 2.0 no signal
522 Hypoglycaemia 75 1.9 2.0 no signal
523 Transient Ischaemic Attack 52 1.9 1.9 no signal
524 Faeces Discoloured 33 1.9 1.9 no signal
525 Head Injury 48 1.9 1.9 no signal
526 Blood Thyroid Stimulating Hormone Increased 14 1.9 1.9 no signal
527 Deep Vein Thrombosis 98 1.9 1.9 no signal
528 Mouth Haemorrhage 11 1.9 1.9 no signal
529 Mucosal Inflammation 39 1.9 1.9 no signal
530 Palmar-plantar Erythrodysaesthesia Syndrome 35 1.9 1.9 no signal
531 Constipation 322 1.9 1.9 no signal
532 Renal Failure Acute 64 1.9 1.9 no signal
533 Nocturia 18 1.9 1.9 no signal
534 Myocardial Ischaemia 17 1.9 1.9 no signal
535 Contusion 142 1.9 1.9 no signal
536 Recalled Product Administered 13 1.9 1.9 no signal
537 Ketoacidosis 11 1.9 1.9 no signal
538 Purpura 13 1.9 1.9 no signal
539 Cholestasis 28 1.8 1.8 no signal
540 Heart Rate Irregular 33 1.8 1.8 no signal
541 Peritonitis 30 1.8 1.8 no signal
542 Nephrolithiasis 66 1.8 1.8 no signal
543 Papule 10 1.8 1.8 no signal
544 Full Blood Count Decreased 29 1.8 1.8 no signal
545 Hypotension 284 1.8 1.8 no signal
546 Chromaturia 32 1.8 1.8 no signal
547 Clostridium Difficile Colitis 15 1.8 1.8 no signal
548 Dysuria 52 1.8 1.8 no signal
549 Retinal Haemorrhage 10 1.8 1.8 no signal
550 Liver Injury 34 1.8 1.8 no signal
551 Bacterial Infection 26 1.8 1.8 no signal
552 Dermatitis 29 1.8 1.8 no signal
553 Hepatic Cirrhosis 26 1.8 1.8 no signal
554 Diverticulum 10 1.7 1.7 no signal
555 Abdominal Discomfort 232 1.7 1.8 no signal
556 Pulmonary Oedema 62 1.7 1.7 no signal
557 Gingival Pain 11 1.7 1.7 no signal
558 Diarrhoea 881 1.7 1.8 no signal
559 Blood Alkaline Phosphatase Increased 34 1.7 1.7 no signal
560 Blood Bilirubin Increased 37 1.7 1.7 no signal
561 Blood Potassium Decreased 41 1.7 1.7 no signal
562 Decubitus Ulcer 11 1.7 1.7 no signal
563 Ischaemic Stroke 24 1.7 1.7 no signal
564 Jaundice 36 1.7 1.7 no signal
565 Electrocardiogram Qt Prolonged 48 1.7 1.7 no signal
566 Blood Calcium Decreased 15 1.7 1.7 no signal
567 Herpes Zoster 76 1.7 1.7 no signal
568 Neuralgia 32 1.7 1.7 no signal
569 Blood Pressure Increased 202 1.7 1.7 no signal
570 Hepatomegaly 13 1.7 1.7 no signal
571 Internal Haemorrhage 15 1.6 1.7 no signal
572 Sudden Death 14 1.6 1.6 no signal
573 Sleep Apnoea Syndrome 25 1.6 1.6 no signal
574 Respiratory Distress 36 1.6 1.6 no signal
575 Metastases To Lung 15 1.6 1.6 no signal
576 Gastric Haemorrhage 15 1.6 1.6 no signal
577 Acute Generalised Exanthematous Pustulosis 10 1.6 1.6 no signal
578 Prescribed Overdose 25 1.6 1.6 no signal
579 Condition Aggravated 389 1.6 1.6 no signal
580 Ejection Fraction Decreased 20 1.6 1.6 no signal
581 Pharyngitis 16 1.6 1.6 no signal
582 Drug Prescribing Error 25 1.6 1.6 no signal
583 Haemorrhagic Stroke 10 1.6 1.6 no signal
584 Encephalopathy 31 1.6 1.6 no signal
585 Skin Disorder 42 1.6 1.6 no signal
586 Scratch 13 1.6 1.6 no signal
587 Feeding Disorder 25 1.6 1.6 no signal
588 Urinary Incontinence 37 1.6 1.6 no signal
589 Transplant Rejection 10 1.6 1.6 no signal
590 Eye Infection 14 1.6 1.6 no signal
591 Colitis 47 1.6 1.6 no signal
592 Myocarditis 14 1.6 1.6 no signal
593 Coronary Artery Occlusion 17 1.6 1.6 no signal
594 Renal Pain 13 1.5 1.5 no signal
595 Diverticulitis 34 1.5 1.6 no signal
596 Product Use Issue 230 1.5 1.6 no signal
597 Limb Discomfort 38 1.5 1.5 no signal
598 Lymphoma 19 1.5 1.5 no signal
599 Leukocytosis 22 1.5 1.5 no signal
600 Infection 174 1.5 1.5 no signal
601 Skin Laceration 13 1.5 1.5 no signal
602 Stomatitis 73 1.5 1.5 no signal
603 Clostridium Difficile Infection 26 1.5 1.5 no signal
604 Muscle Atrophy 15 1.5 1.5 no signal
605 Neutropenia 161 1.5 1.5 no signal
606 Blood Glucose Abnormal 22 1.5 1.5 no signal
607 Blood Iron Decreased 14 1.5 1.5 no signal
608 Shock 27 1.5 1.5 no signal
609 Hypophagia 30 1.5 1.5 no signal
610 Intervertebral Disc Degeneration 11 1.5 1.5 no signal
611 Syncope 118 1.5 1.5 no signal
612 Sensory Disturbance 19 1.5 1.5 no signal
613 Helicobacter Infection 12 1.5 1.5 no signal
614 Haemorrhoids 23 1.5 1.5 no signal
615 Urinary Tract Infection 200 1.5 1.5 no signal
616 Covid-19 208 1.5 1.5 no signal
617 Hyperthyroidism 17 1.5 1.5 no signal
618 Blood Sodium Decreased 22 1.5 1.5 no signal
619 Depressed Level Of Consciousness 46 1.5 1.5 no signal
620 Erectile Dysfunction 30 1.5 1.5 no signal
621 Cholelithiasis 38 1.5 1.5 no signal
622 Blood Urine Present 22 1.5 1.5 no signal
623 Weight Fluctuation 12 1.4 1.5 no signal
624 Nail Disorder 10 1.4 1.4 no signal
625 Hypersensitivity 213 1.4 1.5 no signal
626 Metastases To Liver 20 1.4 1.4 no signal
627 Cardio-respiratory Arrest 48 1.4 1.4 no signal
628 Pruritus Generalised 25 1.4 1.4 no signal
629 Dyspnoea 640 1.4 1.4 no signal
630 Transaminases Increased 25 1.4 1.4 no signal
631 Lung Infiltration 10 1.4 1.4 no signal
632 Fall 370 1.4 1.4 no signal
633 Neoplasm Progression 39 1.4 1.4 no signal
634 Arthralgia 460 1.4 1.4 no signal
635 Diabetes Mellitus 85 1.4 1.4 no signal
636 Delirium 38 1.4 1.4 no signal
637 Exostosis 10 1.4 1.4 no signal
638 Nausea 856 1.4 1.4 no signal
639 Ventricular Fibrillation 12 1.4 1.4 no signal
640 Skin Infection 12 1.4 1.4 no signal
641 Local Swelling 19 1.4 1.4 no signal
642 Neuropathy Peripheral 101 1.3 1.3 no signal
643 Underdose 78 1.3 1.3 no signal
644 Abscess 17 1.3 1.3 no signal
645 Obesity 17 1.3 1.3 no signal
646 Folliculitis 11 1.3 1.3 no signal
647 Tooth Infection 14 1.3 1.3 no signal
648 Oxygen Saturation Decreased 59 1.3 1.3 no signal
649 Blister 59 1.3 1.3 no signal
650 Skeletal Injury 11 1.3 1.3 no signal
651 Myocardial Infarction 183 1.3 1.3 no signal
652 Pneumonitis 28 1.3 1.3 no signal
653 Bronchitis 77 1.3 1.3 no signal
654 Urticaria 172 1.3 1.3 no signal
655 Hypokinesia 15 1.3 1.3 no signal
656 Acute Hepatic Failure 14 1.3 1.3 no signal
657 Vitamin D Deficiency 10 1.3 1.3 no signal
658 Haematemesis 26 1.3 1.3 no signal
659 Muscular Weakness 116 1.3 1.3 no signal
660 Cold Sweat 18 1.3 1.3 no signal
661 Osteoarthritis 43 1.3 1.3 no signal
662 Face Oedema 17 1.3 1.3 no signal
663 Pancreatitis 53 1.3 1.3 no signal
664 Blood Test Abnormal 14 1.3 1.3 no signal
665 Lower Limb Fracture 19 1.3 1.3 no signal
666 Treatment Noncompliance 54 1.3 1.3 no signal
667 Gastritis 26 1.2 1.2 no signal
668 Hip Arthroplasty 15 1.2 1.2 no signal
669 Pulmonary Embolism 94 1.2 1.2 no signal
670 Hepatitis C 12 1.2 1.2 no signal
671 Adverse Reaction 13 1.2 1.2 no signal
672 Chronic Obstructive Pulmonary Disease 51 1.2 1.2 no signal
673 Rhinorrhoea 63 1.2 1.2 no signal
674 Urosepsis 9 1.2 1.2 no signal
675 Paralysis 14 1.2 1.2 no signal
676 Hyperbilirubinaemia 10 1.2 1.2 no signal
677 Appendicitis 9 1.2 1.2 no signal
678 Abdominal Pain 225 1.2 1.2 no signal
679 Loss Of Consciousness 124 1.2 1.2 no signal
680 Petechiae 10 1.2 1.2 no signal
681 Rash Erythematous 45 1.2 1.2 no signal
682 Pericarditis 16 1.2 1.2 no signal
683 Chest Pain 178 1.2 1.2 no signal
684 Hair Colour Changes 12 1.2 1.2 no signal
685 Taste Disorder 19 1.2 1.2 no signal
686 Sciatica 15 1.2 1.2 no signal
687 Headache 591 1.2 1.2 no signal
688 Disease Recurrence 45 1.2 1.2 no signal
689 Supraventricular Tachycardia 9 1.2 1.2 no signal
690 Anaphylactic Shock 24 1.2 1.2 no signal
691 Flatulence 53 1.2 1.2 no signal
692 Skin Discolouration 43 1.2 1.2 no signal
693 Malaise 411 1.2 1.2 no signal
694 Therapy Change 9 1.2 1.2 no signal
695 Palpitations 109 1.2 1.2 no signal
696 Myalgia 157 1.2 1.2 no signal
697 Gastrooesophageal Reflux Disease 74 1.2 1.2 no signal
698 Seasonal Allergy 13 1.2 1.2 no signal
699 Sinus Tachycardia 13 1.2 1.2 no signal
700 Pain In Jaw 26 1.2 1.2 no signal
701 Hospice Care 9 1.1 1.2 no signal
702 Photosensitivity Reaction 15 1.1 1.1 no signal
703 Musculoskeletal Pain 48 1.1 1.1 no signal
704 Pain In Extremity 268 1.1 1.1 no signal
705 Disorientation 36 1.1 1.1 no signal
706 Increased Appetite 17 1.1 1.1 no signal
707 Diabetes Mellitus Inadequate Control 16 1.1 1.1 no signal
708 Hepatic Cytolysis 11 1.1 1.1 no signal
709 Wound 25 1.1 1.1 no signal
710 Asthenia 338 1.1 1.1 no signal
711 Fracture 17 1.1 1.1 no signal
712 Swelling Face 58 1.1 1.1 no signal
713 Oral Pain 20 1.1 1.1 no signal
714 Intestinal Perforation 10 1.1 1.1 no signal
715 Immunodeficiency 13 1.1 1.1 no signal
716 Glaucoma 17 1.1 1.1 no signal
717 Skin Lesion 24 1.1 1.1 no signal
718 Hallucination 66 1.1 1.1 no signal
719 Insomnia 233 1.1 1.1 no signal
720 Movement Disorder 28 1.1 1.1 no signal
721 Localised Infection 21 1.1 1.1 no signal
722 Thrombosis 70 1.1 1.1 no signal
723 Upper Respiratory Tract Infection 40 1.1 1.1 no signal
724 Off Label Use 752 1.1 1.1 no signal
725 Haemorrhage Intracranial 13 1.1 1.1 no signal
726 Prostatic Specific Antigen Increased 12 1.1 1.1 no signal
727 Cough 242 1.1 1.1 no signal
728 Haematotoxicity 8 1.1 1.1 no signal
729 Tenderness 9 1.1 1.1 no signal
730 Infusion Site Pain 11 1.1 1.1 no signal
731 Back Pain 200 1.1 1.1 no signal
732 Abdominal Distension 89 1.1 1.1 no signal
733 Blindness Unilateral 12 1.1 1.1 no signal
734 Gait Inability 28 1.1 1.1 no signal
735 Rash Papular 19 1.1 1.1 no signal
736 Blood Count Abnormal 13 1.1 1.1 no signal
737 Cystitis 27 1.1 1.1 no signal
738 Chest Discomfort 86 1.1 1.1 no signal
739 Viral Infection 28 1.1 1.1 no signal
740 Foot Fracture 16 1.1 1.1 no signal
741 Polyneuropathy 10 1.1 1.1 no signal
742 Posterior Reversible Encephalopathy Syndrome 8 1.1 1.1 no signal
743 Skin Haemorrhage 12 1.0 1.0 no signal
744 Bone Marrow Failure 17 1.0 1.0 no signal
745 Bursitis 10 1.0 1.0 no signal
746 Gastroenteritis Viral 15 1.0 1.0 no signal
747 Wheezing 49 1.0 1.0 no signal
748 Wound Infection 9 1.0 1.0 no signal
749 Cyanosis 13 1.0 1.0 no signal
750 Joint Range Of Motion Decreased 11 1.0 1.0 no signal
751 Gastrointestinal Pain 9 1.0 1.0 no signal
752 Confusional State 133 1.0 1.0 no signal
753 Respiratory Tract Congestion 13 1.0 1.0 no signal
754 Rectal Haemorrhage 35 1.0 1.0 no signal
755 Hypoaesthesia 121 1.0 1.0 no signal
756 Pruritus 305 1.0 1.0 no signal
757 Weight Decreased 225 1.0 1.0 no signal
758 Femur Fracture 25 1.0 1.0 no signal
759 Spinal Fracture 16 1.0 1.0 no signal
760 Upper Limb Fracture 16 1.0 1.0 no signal
761 Fatigue 619 1.0 1.0 no signal
762 Eating Disorder 17 1.0 1.0 no signal
763 Adverse Event 73 1.0 1.0 no signal
764 Respiratory Arrest 22 1.0 1.0 no signal
765 Emphysema 8 1.0 1.0 no signal
766 Dementia 22 1.0 1.0 no signal
767 Heart Rate Increased 78 1.0 1.0 no signal
768 Presyncope 19 1.0 1.0 no signal
769 Muscle Spasms 144 1.0 1.0 no signal
770 Carpal Tunnel Syndrome 11 1.0 1.0 no signal
771 Eye Discharge 8 1.0 1.0 no signal
772 Tooth Abscess 8 1.0 1.0 no signal
773 Disease Progression 92 1.0 1.0 no signal
774 Rib Fracture 16 1.0 1.0 no signal
775 Rotator Cuff Syndrome 10 1.0 1.0 no signal
776 Dizziness 384 1.0 1.0 no signal
777 Oral Herpes 15 1.0 1.0 no signal
778 Product Administered At Inappropriate Site 14 1.0 1.0 no signal
779 Respiratory Tract Infection 20 1.0 1.0 no signal
780 Hypersomnia 22 1.0 1.0 no signal
781 Weight Increased 171 1.0 1.0 no signal
782 Retinal Detachment 7 1.0 1.0 no signal
783 Mouth Ulceration 16 1.0 1.0 no signal
784 Tinnitus 35 1.0 1.0 no signal
785 Immune System Disorder 10 1.0 1.0 no signal
786 Full Blood Count Abnormal 8 1.0 1.0 no signal
787 Chills 89 1.0 1.0 no signal
788 Brain Fog 11 0.9 0.9 no signal
789 Feeling Cold 21 0.9 0.9 no signal
790 Lip Swelling 25 0.9 0.9 no signal
791 Blood Pressure Fluctuation 18 0.9 0.9 no signal
792 Angioedema 33 0.9 0.9 no signal
793 Intestinal Obstruction 28 0.9 0.9 no signal
794 Decreased Activity 8 0.9 0.9 no signal
795 Haemorrhage 78 0.9 0.9 no signal
796 Dysarthria 28 0.9 0.9 no signal
797 Skin Cancer 16 0.9 0.9 no signal
798 Leukaemia 7 0.9 0.9 no signal
799 Muscle Tightness 12 0.9 0.9 no signal
800 Cerebrovascular Accident 126 0.9 0.9 no signal
801 Aspiration 8 0.9 0.9 no signal
802 Limb Injury 20 0.9 0.9 no signal
803 Heart Rate Decreased 26 0.9 0.9 no signal
804 Lung Disorder 36 0.9 0.9 no signal
805 Back Disorder 12 0.9 0.9 no signal
806 Balance Disorder 63 0.9 0.9 no signal
807 Alopecia 143 0.9 0.9 no signal
808 Gait Disturbance 139 0.9 0.9 no signal
809 Sinus Bradycardia 7 0.9 0.9 no signal
810 Leukopenia 36 0.9 0.9 no signal
811 Candida Infection 12 0.9 0.9 no signal
812 Dysphonia 42 0.9 0.9 no signal
813 Plasma Cell Myeloma 28 0.9 0.9 no signal
814 Tooth Disorder 16 0.9 0.9 no signal
815 Kidney Infection 14 0.9 0.9 no signal
816 Thyroid Disorder 11 0.9 0.9 no signal
817 Lethargy 41 0.9 0.9 no signal
818 Type 2 Diabetes Mellitus 24 0.9 0.9 no signal
819 Musculoskeletal Chest Pain 11 0.9 0.9 no signal
820 Tachycardia 63 0.9 0.9 no signal
821 Conjunctivitis 13 0.9 0.9 no signal
822 Abdominal Pain Upper 145 0.9 0.9 no signal
823 Scab 8 0.9 0.9 no signal
824 Micturition Urgency 8 0.9 0.9 no signal
825 Dermatitis Contact 8 0.9 0.9 no signal
826 Hemiparesis 12 0.9 0.9 no signal
827 Vomiting 330 0.9 0.9 no signal
828 Bladder Disorder 7 0.9 0.9 no signal
829 Product Administration Error 14 0.9 0.9 no signal
830 Musculoskeletal Discomfort 12 0.9 0.9 no signal
831 Pain 429 0.9 0.9 no signal
832 Swelling 65 0.9 0.9 no signal
833 Intentional Dose Omission 19 0.9 0.9 no signal
834 Aphasia 21 0.9 0.9 no signal
835 Cataract 41 0.9 0.9 no signal
836 Fungal Infection 23 0.9 0.9 no signal
837 Ankylosing Spondylitis 9 0.9 0.9 no signal
838 Nodule 9 0.9 0.9 no signal
839 Deafness 18 0.9 0.9 no signal
840 Intervertebral Disc Protrusion 15 0.9 0.9 no signal
841 Osteonecrosis Of Jaw 17 0.9 0.9 no signal
842 Head Discomfort 12 0.9 0.9 no signal
843 Abasia 17 0.9 0.9 no signal
844 Vision Blurred 92 0.8 0.8 no signal
845 Pulmonary Mass 10 0.8 0.8 no signal
846 Influenza 75 0.8 0.8 no signal
847 Medication Error 37 0.8 0.8 no signal
848 Cardiovascular Disorder 17 0.8 0.8 no signal
849 Staphylococcal Infection 22 0.8 0.8 no signal
850 Hepatitis 17 0.8 0.8 no signal
851 Lower Respiratory Tract Infection 30 0.8 0.8 no signal
852 Nasopharyngitis 121 0.8 0.8 no signal
853 Diplopia 17 0.8 0.8 no signal
854 Hip Fracture 21 0.8 0.8 no signal
855 Dyspepsia 64 0.8 0.8 no signal
856 Cardiac Arrest 54 0.8 0.8 no signal
857 Back Injury 7 0.8 0.8 no signal
858 Ankle Fracture 10 0.8 0.8 no signal
859 Gastrointestinal Disorder 57 0.8 0.8 no signal
860 Dysphagia 61 0.8 0.8 no signal
861 Mass 9 0.8 0.8 no signal
862 Pulmonary Thrombosis 7 0.8 0.8 no signal
863 Ageusia 16 0.8 0.8 no signal
864 Cardiac Disorder 60 0.8 0.8 no signal
865 Overdose 138 0.8 0.8 no signal
866 Glycosylated Haemoglobin Increased 16 0.8 0.8 no signal
867 Frequent Bowel Movements 17 0.8 0.8 no signal
868 Eructation 12 0.8 0.8 no signal
869 Foot Deformity 7 0.8 0.8 no signal
870 Accidental Overdose 23 0.8 0.8 no signal
871 Impaired Gastric Emptying 8 0.8 0.8 no signal
872 Autoimmune Disorder 6 0.8 0.8 no signal
873 Neck Pain 35 0.8 0.8 no signal
874 Hot Flush 47 0.8 0.8 no signal
875 Knee Arthroplasty 13 0.8 0.8 no signal
876 Inappropriate Schedule Of Product Administration 110 0.8 0.8 no signal
877 Road Traffic Accident 26 0.8 0.8 no signal
878 Hallucination, Visual 13 0.8 0.8 no signal
879 Cholecystectomy 7 0.8 0.8 no signal
880 Nasal Congestion 36 0.8 0.8 no signal
881 Metastases To Bone 10 0.8 0.8 no signal
882 Joint Stiffness 16 0.8 0.8 no signal
883 Malignant Neoplasm Progression 62 0.8 0.8 no signal
884 Death 524 0.8 0.8 no signal
885 Coma 29 0.8 0.8 no signal
886 Ligament Sprain 6 0.8 0.8 no signal
887 Swollen Tongue 19 0.8 0.8 no signal
888 Somnolence 121 0.8 0.8 no signal
889 Salivary Hypersecretion 6 0.8 0.8 no signal
890 Blood Cholesterol Increased 28 0.8 0.8 no signal
891 Bone Disorder 11 0.8 0.8 no signal
892 Amnesia 39 0.8 0.8 no signal
893 Peritonitis Bacterial 6 0.7 0.7 no signal
894 Quality Of Life Decreased 8 0.7 0.7 no signal
895 Oropharyngeal Pain 55 0.7 0.7 no signal
896 Hypothermia 6 0.7 0.7 no signal
897 Tremor 98 0.7 0.7 no signal
898 Inappropriate Antidiuretic Hormone Secretion 6 0.7 0.7 no signal
899 Product Dose Omission 39 0.7 0.7 no signal
900 Accident 7 0.7 0.7 no signal
901 Ataxia 7 0.7 0.7 no signal
902 Blood Glucose Increased 111 0.7 0.7 no signal
903 Drug Level Decreased 6 0.7 0.7 no signal
904 Body Temperature Increased 12 0.7 0.7 no signal
905 Ear Discomfort 6 0.7 0.7 no signal
906 Gastric Cancer 15 0.7 0.7 no signal
907 Unresponsive To Stimuli 15 0.7 0.7 no signal
908 Dysstasia 17 0.7 0.7 no signal
909 Therapy Interrupted 40 0.7 0.7 no signal
910 Eczema 29 0.7 0.7 no signal
911 Sinusitis 59 0.7 0.7 no signal
912 Restlessness 21 0.7 0.7 no signal
913 Lung Infection 9 0.7 0.7 no signal
914 Lacrimation Increased 17 0.7 0.7 no signal
915 Respiratory Disorder 17 0.7 0.7 no signal
916 Pemphigus 7 0.7 0.7 no signal
917 Dysgeusia 42 0.7 0.7 no signal
918 Tooth Extraction 7 0.7 0.7 no signal
919 Blood Glucose Decreased 27 0.7 0.7 no signal
920 Night Sweats 18 0.7 0.7 no signal
921 Epilepsy 17 0.7 0.7 no signal
922 Pain Of Skin 15 0.7 0.7 no signal
923 Skin Exfoliation 46 0.7 0.7 no signal
924 Laryngitis 6 0.7 0.7 no signal
925 Oesophagitis 6 0.7 0.7 no signal
926 Impaired Healing 18 0.7 0.7 no signal
927 Therapy Cessation 28 0.7 0.7 no signal
928 Metastases To Central Nervous System 7 0.7 0.7 no signal
929 Injection Site Nodule 6 0.7 0.7 no signal
930 Bone Pain 32 0.7 0.7 no signal
931 Injection Site Induration 7 0.7 0.7 no signal
932 Feeling Hot 33 0.7 0.7 no signal
933 Obstructive Airways Disorder 6 0.7 0.7 no signal
934 Diarrhoea Haemorrhagic 5 0.7 0.7 no signal
935 Drug Ineffective 701 0.7 0.7 no signal
936 Hypoaesthesia Oral 8 0.7 0.7 no signal
937 Sleep Disorder 37 0.7 0.7 no signal
938 Sopor 7 0.7 0.7 no signal
939 Intentional Product Use Issue 46 0.7 0.7 no signal
940 Feeling Abnormal 125 0.7 0.7 no signal
941 Sinus Congestion 7 0.7 0.7 no signal
942 Product Use In Unapproved Indication 126 0.6 0.6 no signal
943 Lung Neoplasm Malignant 21 0.6 0.6 no signal
944 Toxicity To Various Agents 85 0.6 0.6 no signal
945 Product Physical Issue 10 0.6 0.6 no signal
946 Hospitalisation 76 0.6 0.6 no signal
947 Coordination Abnormal 7 0.6 0.6 no signal
948 Activities Of Daily Living Impaired 10 0.6 0.6 no signal
949 Toothache 9 0.6 0.6 no signal
950 Spinal Operation 6 0.6 0.6 no signal
951 Motor Dysfunction 5 0.6 0.6 no signal
952 Vertigo 30 0.6 0.6 no signal
953 Sneezing 11 0.6 0.6 no signal
954 Anaphylactic Reaction 27 0.6 0.6 no signal
955 Eye Swelling 18 0.6 0.6 no signal
956 Secretion Discharge 6 0.6 0.6 no signal
957 No Therapeutic Response 6 0.6 0.6 no signal
958 Injection Site Discomfort 5 0.6 0.6 no signal
959 Apathy 7 0.6 0.6 no signal
960 Visual Impairment 59 0.6 0.6 no signal
961 Visual Acuity Reduced 16 0.6 0.6 no signal
962 Skin Fissures 9 0.6 0.6 no signal
963 Asthma 53 0.6 0.6 no signal
964 Drug Dose Omission 79 0.6 0.6 no signal
965 Breast Pain 5 0.6 0.6 no signal
966 Mental Status Changes 13 0.6 0.6 no signal
967 Therapy Partial Responder 7 0.6 0.6 no signal
968 Paraesthesia 73 0.6 0.6 no signal
969 Ocular Discomfort 5 0.6 0.6 no signal
970 Rash Macular 16 0.6 0.6 no signal
971 Blood Glucose Fluctuation 5 0.6 0.6 no signal
972 Anhedonia 12 0.6 0.6 no signal
973 Eye Pain 25 0.6 0.6 no signal
974 No Adverse Event 80 0.6 0.6 no signal
975 Drug Administration Error 14 0.6 0.6 no signal
976 Pancreatic Carcinoma 13 0.6 0.6 no signal
977 Product Prescribing Issue 9 0.6 0.6 no signal
978 Laboratory Test Abnormal 13 0.6 0.6 no signal
979 Nerve Compression 4 0.5 0.5 no signal
980 Dry Mouth 35 0.5 0.5 no signal
981 Device Occlusion 6 0.5 0.5 no signal
982 Oral Discomfort 6 0.5 0.5 no signal
983 Middle Insomnia 8 0.5 0.5 no signal
984 Personality Change 4 0.5 0.5 no signal
985 Eye Disorder 14 0.5 0.5 no signal
986 Spinal Pain 5 0.5 0.5 no signal
987 Therapeutic Response Unexpected 19 0.5 0.5 no signal
988 Macular Degeneration 5 0.5 0.5 no signal
989 Laceration 4 0.5 0.5 no signal
990 Bronchospasm 6 0.5 0.5 no signal
991 Hypoacusis 18 0.5 0.5 no signal
992 Hyperhidrosis 54 0.5 0.5 no signal
993 Muscle Rigidity 5 0.5 0.5 no signal
994 Anxiety 119 0.5 0.5 no signal
995 Affect Lability 4 0.5 0.5 no signal
996 Osteoporosis 17 0.5 0.5 no signal
997 Cognitive Disorder 19 0.5 0.5 no signal
998 Wrong Technique In Product Usage Process 82 0.5 0.5 no signal
999 Dry Skin 53 0.5 0.5 no signal
1000 Glossodynia 9 0.5 0.5 no signal
1001 Cyst 5 0.5 0.5 no signal
1002 Product Availability Issue 9 0.5 0.5 no signal
1003 Injection Site Extravasation 5 0.5 0.5 no signal
1004 Memory Impairment 55 0.5 0.5 no signal
1005 Multi-organ Failure 7 0.5 0.5 no signal
1006 Hypotonia 4 0.5 0.5 no signal
1007 Brain Injury 4 0.5 0.5 no signal
1008 Procedural Pain 11 0.5 0.5 no signal
1009 Ovarian Cyst 4 0.5 0.5 no signal
1010 Discomfort 24 0.5 0.5 no signal
1011 Eyelid Ptosis 4 0.5 0.5 no signal
1012 Osteonecrosis 13 0.5 0.5 no signal
1013 Mental Disorder 17 0.5 0.5 no signal
1014 Economic Problem 6 0.5 0.5 no signal
1015 Product Odour Abnormal 4 0.5 0.5 no signal
1016 Burning Sensation 27 0.5 0.5 no signal
1017 Pharyngeal Oedema 6 0.5 0.5 no signal
1018 Intentional Product Misuse 33 0.5 0.5 no signal
1019 Surgery 22 0.5 0.5 no signal
1020 Illness 38 0.5 0.5 no signal
1021 Ear Infection 10 0.5 0.5 no signal
1022 Diabetic Ketoacidosis 9 0.5 0.5 no signal
1023 Malignant Melanoma 5 0.5 0.5 no signal
1024 Flushing 38 0.5 0.5 no signal
1025 Body Height Decreased 4 0.5 0.5 no signal
1026 Pharyngitis Streptococcal 4 0.5 0.5 no signal
1027 Seizure 42 0.5 0.5 no signal
1028 Ocular Hyperaemia 17 0.5 0.5 no signal
1029 Hernia 7 0.5 0.5 no signal
1030 Inappropriate Schedule Of Drug Administration 26 0.5 0.5 no signal
1031 Unevaluable Event 27 0.4 0.4 no signal
1032 Drug Effect Incomplete 13 0.4 0.4 no signal
1033 Psoriasis 46 0.4 0.4 no signal
1034 Gynaecomastia 11 0.4 0.4 no signal
1035 Nervous System Disorder 11 0.4 0.4 no signal
1036 Drug Resistance 9 0.4 0.4 no signal
1037 Dyskinesia 14 0.4 0.4 no signal
1038 Blindness 14 0.4 0.4 no signal
1039 Speech Disorder 18 0.4 0.4 no signal
1040 Product Dose Omission Issue 97 0.4 0.4 no signal
1041 Colitis Ulcerative 15 0.4 0.4 no signal
1042 Mood Altered 9 0.4 0.4 no signal
1043 Dry Eye 16 0.4 0.4 no signal
1044 Neoplasm Malignant 22 0.4 0.4 no signal
1045 Device Failure 5 0.4 0.4 no signal
1046 Hepatic Cancer 8 0.4 0.4 no signal
1047 Ill-defined Disorder 20 0.4 0.4 no signal
1048 Skin Irritation 15 0.4 0.4 no signal
1049 Brain Neoplasm 3 0.4 0.4 no signal
1050 Respiratory Depression 4 0.4 0.4 no signal
1051 Deformity 3 0.4 0.4 no signal
1052 Depression 73 0.4 0.4 no signal
1053 Bone Density Decreased 10 0.4 0.4 no signal
1054 Incorrect Drug Administration Duration 9 0.4 0.4 no signal
1055 Feeling Jittery 6 0.4 0.4 no signal
1056 Tuberculosis 4 0.4 0.4 no signal
1057 Knee Operation 3 0.4 0.4 no signal
1058 Hand Deformity 4 0.4 0.4 no signal
1059 Coeliac Disease 3 0.4 0.4 no signal
1060 Inability To Afford Medication 3 0.4 0.4 no signal
1061 Injection Site Bruising 24 0.4 0.4 no signal
1062 Adverse Drug Reaction 27 0.4 0.4 no signal
1063 Incorrect Product Storage 4 0.4 0.4 no signal
1064 Psychomotor Hyperactivity 5 0.4 0.4 no signal
1065 Eye Haemorrhage 4 0.4 0.4 no signal
1066 Hair Texture Abnormal 4 0.4 0.4 no signal
1067 Product Substitution Issue 17 0.4 0.4 no signal
1068 Poor Quality Product Administered 3 0.4 0.4 no signal
1069 Injection Site Warmth 6 0.4 0.4 no signal
1070 Product Preparation Error 6 0.4 0.4 no signal
1071 Incorrect Dose Administered 65 0.4 0.4 no signal
1072 Nervousness 15 0.4 0.4 no signal
1073 Hepatocellular Injury 4 0.4 0.4 no signal
1074 Influenza Like Illness 23 0.4 0.3 no signal
1075 Stress 20 0.3 0.3 no signal
1076 Product Dispensing Error 6 0.3 0.3 no signal
1077 Prostate Cancer 22 0.3 0.3 no signal
1078 Injection Site Pruritus 18 0.3 0.3 no signal
1079 Throat Irritation 12 0.3 0.3 no signal
1080 Fistula 3 0.3 0.3 no signal
1081 Device Issue 23 0.3 0.3 no signal
1082 Disturbance In Attention 14 0.3 0.3 no signal
1083 Abnormal Dreams 7 0.3 0.3 no signal
1084 Abnormal Behaviour 10 0.3 0.3 no signal
1085 Renal Cancer 12 0.3 0.3 no signal
1086 Sleep Disorder Due To A General Medical Condition 4 0.3 0.3 no signal
1087 Schizophrenia 3 0.3 0.3 no signal
1088 Incorrect Product Administration Duration 5 0.3 0.3 no signal
1089 Injection Site Discolouration 3 0.3 0.3 no signal
1090 Expired Product Administered 8 0.3 0.3 no signal
1091 Abnormal Weight Gain 3 0.3 0.3 no signal
1092 Poisoning 3 0.3 0.3 no signal
1093 Injection Site Irritation 3 0.3 0.3 no signal
1094 Drug Ineffective For Unapproved Indication 13 0.3 0.3 no signal
1095 Device Use Issue 4 0.3 0.3 no signal
1096 Depressed Mood 12 0.3 0.3 no signal
1097 Product Adhesion Issue 8 0.3 0.3 no signal
1098 Therapeutic Response Shortened 7 0.3 0.3 no signal
1099 Agitation 16 0.3 0.3 no signal
1100 Device Malfunction 14 0.3 0.3 no signal
1101 Device Dislocation 9 0.3 0.3 no signal
1102 Bladder Cancer 12 0.3 0.3 no signal
1103 Product Quality Issue 27 0.3 0.3 no signal
1104 Injury 14 0.2 0.2 no signal
1105 Injection Site Rash 6 0.2 0.2 no signal
1106 Drug Dispensing Error 3 0.2 0.2 no signal
1107 Migraine 18 0.2 0.2 no signal
1108 Injection Site Reaction 13 0.2 0.2 no signal
1109 Drug Effect Decreased 10 0.2 0.2 no signal
1110 Injection Site Pain 55 0.2 0.2 no signal
1111 Aggression 9 0.2 0.2 no signal
1112 Eye Irritation 10 0.2 0.2 no signal
1113 Injection Site Haemorrhage 14 0.2 0.2 no signal
1114 Extra Dose Administered 7 0.2 0.2 no signal
1115 Vaginal Haemorrhage 7 0.2 0.2 no signal
1116 Injection Site Erythema 20 0.2 0.2 no signal
1117 Breast Cancer 15 0.2 0.2 no signal
1118 Acne 12 0.2 0.2 no signal
1119 Emotional Distress 19 0.2 0.2 no signal
1120 Irritability 9 0.2 0.2 no signal
1121 Intentional Drug Misuse 3 0.2 0.2 no signal
1122 Intentional Overdose 9 0.2 0.2 no signal
1123 Tardive Dyskinesia 4 0.2 0.2 no signal
1124 Dermatitis Atopic 7 0.2 0.2 no signal
1125 Needle Issue 4 0.2 0.2 no signal
1126 Wrong Technique In Drug Usage Process 5 0.2 0.2 no signal
1127 Oesophageal Carcinoma 4 0.2 0.2 no signal
1128 Suicidal Ideation 12 0.2 0.2 no signal
1129 Skin Burning Sensation 9 0.2 0.2 no signal
1130 Injection Site Urticaria 3 0.2 0.2 no signal
1131 Device Leakage 5 0.1 0.1 no signal
1132 Breast Cancer Female 3 0.1 0.1 no signal
1133 Wrong Technique In Device Usage Process 4 0.1 0.1 no signal
1134 Incorrect Route Of Drug Administration 3 0.1 0.1 no signal
1135 Device Breakage 3 0.1 0.1 no signal
1136 Device Difficult To Use 3 0.1 0.1 no signal