Reaction

Rheumatoid Nodule reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,749 reports · 120 co-occurring drugs

As of the last recalculation, Rheumatoid Nodule appears in 2,749 FAERS reports alongside 120 co-occurring drug terms. The strongest observed disproportionality signal is METHYLPREDNISOLONE ACETATE (PRR 138.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Methylprednisolone Acetate	139	138.4	140.8
Leflunomide	1,120	136.1	137.5
Dimenhydrinate	157	118.2	120.0
Febuxostat Tablets 40 Mg	143	112.3	113.9
Febuxostat Tablets 80 Mg	143	112.3	113.9
Tocilizumab	994	102.8	103.7
Sulfasalazine	761	101.5	102.4
Hydroxychloroquine Sulfate	756	86.3	87.0
Abatacept	972	81.7	82.2
Febuxostat	164	78.7	79.5
Risedronate Sodium	280	75.8	76.5
Esomeprazole Magnesium Capsule, Delayed Release	136	74.6	75.3
Esomeprazole Magnesium Delayed Release Capsules	136	74.6	75.3
Methotrexate Sodium	1,759	74.3	74.6
Tofacitinib Citrate	123	74.3	75.0
Esomeprazole Magnesium Dihydrate	136	74.3	75.0
Hydroxychloroquine	551	69.6	70.2
Methotrexate	1,542	61.9	62.1
Naproxen Sodium Tablet, Coated	104	60.4	60.9
Naproxen Sodium, Coated Tablets	104	60.4	60.9
Naproxen Sodium 220Mg	104	60.3	60.8
Alendronate Sodium	592	56.3	56.7
Golimumab	504	54.3	54.6
Tofacitinib	882	52.8	53.1
Cortisone Acetate	83	52.5	52.8
Colchicine	163	49.8	50.1
Desoximetasone	118	49.0	49.3
Diltiazem Hydrochloride Extended-Release Tablets	71	48.5	48.8
Adalimumab-Fkjp	252	45.2	45.5
Adalimumab-Aaty	252	44.3	44.5
Rituximab	834	42.4	42.6
Naproxen	379	42.2	42.4
Ibuprofen And Diphenhydramine Citrate	118	40.1	40.3
Adalimumab-Adaz	254	40.1	40.2
Dexlansoprazole	186	36.1	36.3
Certolizumab Pegol	466	36.0	36.2
Iron Sucrose	40	32.2	32.4
Telmisartan	73	31.8	31.9
Infliximab	684	31.2	31.3
Celecoxib	442	30.1	30.2
Etanercept	1,295	30.1	30.1
Trimethoprim	46	30.0	30.1
Azathioprine	303	29.1	29.2
Pramipexole	57	28.7	28.8
Doxyclycline Hyclate	63	28.6	28.7
Alendronate Sodium Tablet	68	28.5	28.6
Cyanocobalamin	110	26.3	26.4
Naproxen Sodium	414	25.7	25.7
Diphenhydramine Hydrochloride Capsule, Liquid Filled	68	24.7	24.8
Esomeprazole	185	24.1	24.2
Meloxicam	171	23.7	23.8
Adalimumab	1,249	23.7	23.7
Cyclosporine	275	20.7	20.7
Prednisone	924	20.4	20.5
Amitriptyline Hydrochloride	46	20.2	20.2
Folic Acid	536	20.0	20.0
Magnesium Oxide	105	19.7	19.8
Diltiazem Hydrochloride	81	18.2	18.3
Budesonide	108	14.4	14.4
Pantoprazole Sodium In 0.9% Sodium Chloride	113	14.3	14.4
Pantoprazole Sodium Injection	113	14.3	14.4
Ustekinumab	165	12.9	12.9
Propranolol Hydrochloride	110	12.0	12.0
Anakinra	26	12.0	12.0
Iron	102	12.0	12.0
Ibuprofen Capsule	269	11.2	11.2
Ibuprofen Tablet, Film Coated	269	11.2	11.2
Ibupfrofen	269	11.2	11.2
Ibuprofen Tablets Usp, 200Mg	269	11.2	11.2
Ibuprofen Oral	269	11.2	11.2
Ibuprofen Capsules 200 Mg	269	11.2	11.2
Ibuprofen 200 Mg	269	11.2	11.2
Ibuprofen 200Mg	269	11.2	11.2
Ixekizumab	53	11.0	11.1
Bendamustine Hydrochloride	17	10.8	10.8
Diphenhydramine Hydrochloride	216	10.6	10.6
Diclofenac	115	10.5	10.5
Ramipril	148	9.5	9.5
Tranexamic Acid	11	9.4	9.4
Apremilast	170	9.3	9.3
Prednisolone	206	9.3	9.3
Prednisolone Oral	206	9.3	9.3
Prednisolone Oral Solution	206	9.3	9.3
Paroxetine Hydrochloride Hemihydrate	40	9.2	9.2
Doxycycline Hyclate	79	9.1	9.1
Paroxetine	40	9.0	9.0
Ibuprofen	293	9.0	9.0
Doxycycline	79	9.0	9.0
Secukinumab	178	8.9	8.9
Bendamustine Hcl	18	8.8	8.8
Bupropion	51	8.8	8.8
Methylprednisolone Sodium Succinate	53	8.8	8.8
Oxazepam	23	8.2	8.2
Baricitinib	10	7.9	7.9
Pregabalin	253	7.7	7.7
Oxycodone	175	7.5	7.5
Atenolol	121	7.1	7.2
Esomeprazole Magnesium	204	7.0	7.1
Diclofenac Sodium	126	6.6	6.6
Oxycodone And Acetaminophen Tablets	10	6.4	6.4
Pantoprazole	199	6.3	6.3
Diclofenac Potassium, Film Coated	7	6.3	6.3
Diclofenac Potassium Tablets	7	6.3	6.3
Paroxetine Hydrochloride	74	6.3	6.3
Pantoprazole Sodium	114	6.0	6.0
Sulfamethoxazole And Trimethoprim	65	6.0	6.0
Bisoprolol Fumarate	101	5.8	5.8
Pemetrexed	15	5.3	5.3
Morphine Sulfate	77	4.9	4.9
Diclofenac Potassium	7	4.9	4.9
Sarilumab	16	4.6	4.6
Acetaminophen And Codeine	7	4.4	4.4
Ranitidine Hydrochloride	29	4.1	4.1
Pemetrexed Disodium	20	4.0	4.0
Oxycodone Hydrochloride	96	3.4	3.4
Upadacitinib	34	3.2	3.2
Pseudoephedrine Hydrochloride	4	3.0	3.0
Ranitidine	74	2.9	2.9
Pseudoephedrine Hcl	4	2.8	2.8
Pegfilgrastim	18	1.4	1.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.