Reaction

Alanine Aminotransferase Abnormal reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,071 reports · 142 co-occurring drugs

As of the last recalculation, Alanine Aminotransferase Abnormal appears in 2,071 FAERS reports alongside 142 co-occurring drug terms. The strongest observed disproportionality signal is FEBUXOSTAT TABLETS 40 MG (PRR 140.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Febuxostat Tablets 40 Mg	133	140.4	142.3
Febuxostat Tablets 80 Mg	133	140.4	142.3
Dimenhydrinate	124	124.3	125.8
Febuxostat	142	91.3	92.1
Colchicine	140	57.2	57.5
Ibuprofen And Diphenhydramine Citrate	115	52.5	52.8
Desoximetasone	78	42.7	42.9
Dexlansoprazole	147	38.1	38.2
Risedronate Sodium	109	37.1	37.3
Methylprednisolone Acetate	29	36.9	37.0
Adalimumab-Fkjp	145	33.8	33.9
Adalimumab-Aaty	145	33.0	33.1
Sulfasalazine	224	32.1	32.2
Adalimumab-Adaz	145	29.6	29.7
Leflunomide	247	26.8	26.9
Golimumab	184	23.6	23.6
Itraconazole	27	23.5	23.6
Ribociclib	67	22.0	22.1
Hydroxychloroquine Sulfate	180	21.7	21.7
Axicabtagene Ciloleucel	21	21.6	21.6
Fluticasone Furoate	24	20.1	20.2
Ustekinumab	184	19.7	19.8
Diphenhydramine Hydrochloride Capsule, Liquid Filled	39	18.7	18.7
Ursosiol	33	17.3	17.3
Tocilizumab	180	17.3	17.3
Certolizumab Pegol	184	17.2	17.2
Abatacept	214	17.2	17.2
Hydroxychloroquine	117	16.6	16.7
Ursodiol	33	15.5	15.5
Naproxen	110	14.8	14.8
Alendronate Sodium	138	14.7	14.7
Cyclosporine	148	14.3	14.3
Apremilast	184	13.8	13.8
Anastrozole Tablets	28	13.3	13.3
Canagliflozin	36	12.3	12.3
Fulvestrant	39	12.1	12.1
Brentuximab Vedotin	12	11.8	11.8
Infliximab	227	11.6	11.6
Darunavir	17	11.4	11.4
Letrozole Tablets	52	11.1	11.1
Secukinumab	161	10.8	10.8
Folic Acid	225	10.1	10.1
Raltegravir	16	9.8	9.8
Leucovorin Calcium	18	9.5	9.5
Rituximab	182	9.4	9.4
Diphenhydramine Hydrochloride	141	9.1	9.1
Methotrexate	327	9.1	9.1
Oxycodone	154	8.9	8.9
Letrozole	52	8.7	8.7
Methotrexate Sodium	355	8.7	8.7
Anastrozole	31	8.6	8.6
Naproxen Sodium	114	8.4	8.4
Sennosides 8.6 Mg Tablets	17	8.2	8.2
Lopinavir And Ritonavir	11	8.2	8.2
Senna	17	8.2	8.2
Senna Leaf	18	7.9	7.9
Metformin Hydrochloride Tablets	44	7.9	7.9
Metformin Hydrochloride Extended-Release Tablets	44	7.9	7.9
Metformin Hydrochloride Tablet	44	7.9	7.9
Ibuprofen Capsule	144	7.7	7.7
Ibuprofen Tablet, Film Coated	144	7.7	7.7
Ibupfrofen	144	7.7	7.7
Ibuprofen Tablets Usp, 200Mg	144	7.7	7.7
Ibuprofen Oral	144	7.7	7.7
Ibuprofen Capsules 200 Mg	144	7.7	7.7
Ibuprofen 200 Mg	144	7.7	7.7
Ibuprofen 200Mg	144	7.7	7.7
Celecoxib	96	7.6	7.6
Metformin Hydrochloride	44	7.6	7.6
Pemetrexed	16	7.6	7.6
Zidovudine	10	7.5	7.6
Dapagliflozin	23	7.4	7.4
Erlotinib	7	7.3	7.3
Erlotinib Hydrochloride	9	7.3	7.3
Daspone	7	7.2	7.2
Tofacitinib	126	7.2	7.2
Dapsone Gel, 5%	7	7.2	7.2
Ritonavir	20	6.9	6.9
Fenofibrate	24	6.9	6.9
Doxorubicin Hydrochloride	22	6.8	6.8
Dapsone	7	6.6	6.6
Nilotinib	19	6.5	6.5
Pyrazinamide	6	6.4	6.4
Pemetrexed Disodium	24	6.4	6.4
Abacavir Sulfate	6	6.2	6.2
Regorafenib	7	6.1	6.1
Oxaliplatin	44	6.1	6.1
Micafungin Sodium	5	5.9	5.9
Paclitaxel (Aibumin-Bound)	47	5.9	5.9
Blinatumomab	6	5.8	5.8
Bevacizumab	69	5.8	5.8
Dabrafenib	12	5.8	5.8
Mepolizumab	28	5.7	5.7
Oxycodone Hydrochloride	117	5.7	5.7
Doxorubicin	49	5.6	5.6
Conjugated Estrogens	32	5.6	5.6
Etanercept	293	5.6	5.6
Rifampin	8	5.5	5.5
Estrogens, Conjugated	32	5.5	5.5
Pembrolizumab	56	5.5	5.5
Sorafenib	11	5.3	5.3
Remdesivir	7	5.3	5.3
Cabozantinib	25	5.3	5.3
Adalimumab	321	5.2	5.2
Lapatinib	8	5.2	5.2
Ifosfamide	11	5.2	5.2
Paclitaxel	49	5.1	5.1
Trametinib	12	5.0	5.0
Carboplatin	61	4.9	4.9
Mesna Injection	4	4.9	4.9
Mesna	4	4.8	4.8
Velpatasvir And Sofosbuvir	6	4.7	4.7
Tenofovir Disoproxil Fumarate Tablets	4	4.7	4.7
Canakinumab	5	4.7	4.7
Capecitabine	38	4.2	4.2
Tolvaptan	6	4.2	4.2
Temozolomide	8	3.8	3.8
Oseltamivir	3	3.8	3.8
Derma Foam Excel Hand Sanitizer	3	3.8	3.8
Ethanol	3	3.8	3.8
Cabotegravir	3	3.7	3.7
Ledipasvir And Sofosbuvir	7	3.7	3.7
Tenofovir Disoproxil Fumarate	12	3.7	3.7
Ribavirin	23	3.6	3.6
Ado-Trastuzumab Emtansine	3	3.6	3.6
Emtricitabine And Tenofovir Disoproxil Fumarate	16	3.5	3.5
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	3	3.4	3.4
Vemurafenib	4	3.3	3.4
Gefitinib	3	3.3	3.3
Cariprazine	3	3.2	3.2
Voxelotor	7	3.1	3.1
Teriflunomide	14	3.1	3.1
Fam-Trastuzumab Deruxtecan-Nxki	3	3.0	3.0
Cetuximab	9	2.9	2.9
Osimertinib	9	2.8	2.8
Tafamidis	3	2.6	2.6
Sofosbuvir	5	2.6	2.6
Isotretinoin	12	2.4	2.4
Elexacaftor, Tezacaftor, And Ivacaftor	3	2.4	2.4
Crizotinib	3	2.4	2.4
Peginterferon Beta-1A	3	2.3	2.3
Erenumab-Aooe	8	1.5	1.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.