Reaction

Hyperuricaemia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,048 reports · 291 co-occurring drugs

As of the last recalculation, Hyperuricaemia appears in 4,048 FAERS reports alongside 291 co-occurring drug terms. The strongest observed disproportionality signal is FEBUXOSTAT TABLETS 40 MG (PRR 39.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Febuxostat Tablets 40 Mg	76	39.1	39.4
Febuxostat Tablets 80 Mg	76	39.1	39.4
Pyrazinamide	65	36.1	36.4
Polatuzumab Vedotin	53	28.3	28.4
Febuxostat	89	27.9	28.0
Tolvaptan	74	26.7	26.8
Pitavastatin Calcium	48	24.4	24.5
Dexamethasone Sodium Phosphate	47	24.1	24.2
Basiliximab	49	21.7	21.8
Eplerenone	48	19.5	19.6
Sodium Bicarbonate Injection,	84	18.9	19.0
Sodium Bicarbonate	83	18.7	18.8
Isoniazid	56	18.0	18.1
Allopurinol	467	17.2	17.3
Bendamustine Hcl	50	16.8	16.8
Ribavirin	199	16.7	16.7
Micafungin Sodium	27	16.5	16.5
Valganciclovir Hydrochloride Powder,	37	15.7	15.8
Mesna	25	15.4	15.4
Mesna Injection	24	15.0	15.1
Rifampicin	29	14.8	14.9
Torsemide	90	14.3	14.3
Ursodiol	55	13.1	13.2
Valganciclovir	46	12.7	12.7
Valganciclovir Hydrochloride	46	12.7	12.7
Acetylcysteine	20	11.0	11.0
Entecavir	24	10.6	10.6
Candesartan Cilexetil	53	10.5	10.5
Venetoclax	114	9.8	9.8
Ritonavir	54	9.6	9.6
Atovaquone	15	9.6	9.6
Rabeprazole	41	9.6	9.6
Brentuximab Vedotin	19	9.6	9.6
Granisetron Hydrochloride	19	9.4	9.4
Cimetidine	17	9.1	9.1
Raltegravir	29	9.1	9.1
Hydroxyurea	36	8.8	8.8
Magnesium Oxide	70	8.7	8.8
Atazanavir	24	8.6	8.6
Ganciclovir Sodium	17	8.3	8.3
Colchicine	42	8.3	8.3
Heparin Sodium	22	8.3	8.3
Ganciclovir	16	8.1	8.1
Valacyclovir	64	8.0	8.0
Magnesium Sulfate Heptahydrate	20	7.9	7.9
Piperacillin Sodium And Tazobactam Sodium	30	7.9	7.9
Valsartan	153	7.7	7.7
Magnesium Sulfate In Water For	19	7.7	7.7
Anti-Thymocyte Globulin (Rabbit)	12	7.7	7.7
Magnesium Sulfate	19	7.5	7.5
Amlodipine Besylate And Valsartan	16	7.5	7.5
Dolutegravir Sodium	13	7.4	7.4
Rabeprazole Sodium	39	7.4	7.4
Bisoprolol Fumarate	188	7.4	7.4
Abacavir Sulfate	14	7.4	7.4
Valsartan Oral	77	7.4	7.4
Lamivudine	44	7.4	7.4
Melphalan	32	7.3	7.3
Lopinavir And Ritonavir	19	7.2	7.2
Ursosiol	27	7.2	7.2
Dapagliflozin	43	7.1	7.1
Lubiprostone	13	7.1	7.1
Methylprednisolone Sodium Succinate	63	7.1	7.1
Itraconazole	16	7.1	7.1
Doxazosin	38	7.0	7.0
Leucovorin Calcium	26	7.0	7.0
Furosemide	485	6.9	6.9
Ezetimibe	99	6.9	6.9
Bendamustine Hydrochloride	16	6.9	6.9
Calcium Gluconate	16	6.9	6.9
Emtricitabine And Tenofovir Alafenamide	15	6.8	6.8
Sorafenib	27	6.7	6.7
Doxazosin Mesylate	46	6.6	6.6
Mycophenolic Acid	40	6.5	6.5
Mometasone	23	6.5	6.5
Bisacodyl Suppositories	16	6.4	6.4
Biscodyl	16	6.3	6.3
Nifedipine	57	6.3	6.3
Tacrolimus Ointment 0.1%	146	6.2	6.2
Chlorhexidine Gluconate	11	6.2	6.2
Tacrolimus Extended-Release Capsules	146	6.2	6.2
Tacrolimus	181	6.2	6.2
Darunavir	18	6.1	6.1
Hydrocortisone Sodium Succinate	11	6.0	6.0
Cefazolin Sodium	14	6.0	6.0
Obinutuzumab	19	6.0	6.0
Calcitriol Capsules 0.25 Mcg	23	5.9	5.9
Calcitriol Capsules 0.5 Mcg	23	5.9	5.9
Sulfamethoxazole And Trimethoprim	95	5.9	5.9
Ketoprofen	15	5.9	5.9
Bisacodyl	16	5.9	5.9
Calcitriol	23	5.9	5.9
Everolimus Tablets	19	5.8	5.9
Nebivolol	18	5.8	5.8
Candesartan	40	5.8	5.8
Indapamide	20	5.8	5.8
Doxorubicin Hydrochloride	36	5.7	5.7
Rifampin	16	5.7	5.7
Levofloxacin	65	5.6	5.6
Levofloxacin In 5% Dextrose	65	5.6	5.6
Ibrutinib	86	5.6	5.6
Isosorbide Dinitrate	21	5.6	5.6
Spironolactone	147	5.5	5.5
Amlodipine Besylate	152	5.5	5.5
Moxifloxacin	15	5.5	5.5
Valacyclovir Hydrochloride	74	5.5	5.5
Cytarabine	63	5.5	5.5
Doxorubicin	92	5.4	5.4
Theophylline	12	5.4	5.4
Meropenem	33	5.3	5.3
Lamivudine Oral	26	5.3	5.3
Anakinra	17	5.3	5.3
Nilotinib	30	5.3	5.3
Metoprolol Succinate Er Tablets	63	5.3	5.3
Linezolid	30	5.2	5.2
Telmisartan	18	5.2	5.2
Etoposide	73	5.2	5.2
Rituximab	203	5.1	5.1
Fluconazole	69	5.1	5.1
Cyclosporine	108	5.1	5.1
Moxifloxacin Hydrochloride	20	5.1	5.1
Piperacillin Sodium,Tazobactam Sodium	26	5.1	5.1
Tamsulosin Hydrochloride	20	5.1	5.1
Indomethacin	13	5.1	5.1
Theophylline Anhydrous	12	5.0	5.0
Sotalol Hydrochloride	16	5.0	5.0
Peginterferon Alfa-2A	51	4.9	4.9
Dalteparin Sodium	10	4.9	4.9
Mycophenolate Mofetil	125	4.9	4.9
Mycophenolate Mofetil Hydrochloride	125	4.8	4.8
Piperacillin And Tazobactam	12	4.8	4.8
Captopril	9	4.8	4.8
Erythropoietin	19	4.8	4.8
Nystatin Ointment	24	4.7	4.7
Isosorbide Mononitrate	19	4.7	4.7
Nystatin Cream	24	4.7	4.7
Cyclophosphamide Injection, Solution	156	4.7	4.7
Cyclophosphamide	156	4.7	4.7
Cyclophosphamide For Injection	156	4.7	4.7
Potassium Chloride, Dextrose Monohydrate	82	4.6	4.6
Potassium Chloride Oral	82	4.6	4.6
Zidovudine	12	4.6	4.6
Potassium Chloride Extended-Release	82	4.6	4.6
Ceftriaxone Sodium	34	4.6	4.6
Metolazone	10	4.6	4.6
Amikacin	15	4.5	4.5
Nystatin	24	4.5	4.5
Melphalan Hydrochloride	22	4.5	4.5
Ruxolitinib	62	4.5	4.5
Bleomycin Sulfate	9	4.5	4.5
Cefepime Hydrochloride	14	4.5	4.5
Fexofenadine Hcl	8	4.5	4.5
Esomeprazole	53	4.4	4.4
Voriconazole	26	4.4	4.4
Granisetron	9	4.4	4.4
Filgrastim	32	4.4	4.4
Sunitinib Malate	33	4.3	4.3
Fludarabine Phosphate	33	4.3	4.3
Lactulose	32	4.3	4.3
Olmesartan Medoxomil	30	4.3	4.3
Letrozole Tablets	40	4.3	4.3
Enalapril	46	4.3	4.3
Deferasirox	22	4.3	4.3
Everolimus	42	4.3	4.3
Voriconazole Injection	18	4.3	4.3
Linagliptin	15	4.2	4.2
Lidocaine Hydrochloride	49	4.2	4.2
Prednisolone	144	4.2	4.2
Prednisolone Oral	144	4.2	4.2
Prednisolone Oral Solution	144	4.2	4.2
Methoxy Polyethylene Glycol-Epoetin Beta	9	4.2	4.2
Amoxicillin And Clavulanate Potassium	22	4.2	4.2
Azacitidine	24	4.2	4.2
Enalapril Maleate	20	4.2	4.2
Ramipril	98	4.1	4.1
Ritonavir 100 Mg	12	4.1	4.1
Cisplatin	62	4.1	4.1
Amphotericin B	10	4.1	4.1
Exemestane	17	4.1	4.1
Imatinib	14	4.1	4.1
Metoprolol Succinate	68	4.1	4.1
Levocetirizine Dihydrochloride	19	4.1	4.1
Acyclovir	89	4.1	4.1
Bosutinib	7	4.0	4.0
Clobetasol Propionate Ointment Usp, 0.05%	8	4.0	4.0
Clobetasol Propionate	8	4.0	4.0
Amlodipine	198	3.9	3.9
Potassium Chloride	85	3.9	3.9
Carfilzomib	21	3.8	3.8
Acalabrutinib	9	3.8	3.8
Lansoprazole	129	3.8	3.8
Pegaspargase	9	3.8	3.8
Vancomycin Hydrochloride	48	3.8	3.8
Darbepoetin Alfa	39	3.7	3.7
Fosaprepitant Dimeglumine	10	3.7	3.7
Instalax Polyethylene Glycol 3350	9	3.7	3.7
Letrozole	44	3.7	3.7
Efavirenz	8	3.7	3.7
Famotidine	83	3.7	3.7
Carvedilol	95	3.7	3.7
Nebivolol Hydrochloride	24	3.7	3.7
Pemetrexed Disodium	27	3.7	3.7
Polyethylene Glycol 400	9	3.7	3.7
Lapatinib	11	3.7	3.7
Pravastatin Sodium	14	3.6	3.6
Aprepitant	13	3.6	3.6
Pazopanib Hydrochloride	19	3.6	3.6
Loperamide Hcl	9	3.6	3.6
Insulin Glargine-Yfgn	15	3.5	3.5
Loperamide Hydrochloride Oral	7	3.5	3.5
Dextrose	9	3.5	3.5
Vancomycin	39	3.5	3.5
Metoclopramide	37	3.5	3.5
Irbesartan	30	3.5	3.5
Dextrose Monohydrate	9	3.5	3.5
Clarithromycin	23	3.5	3.5
Warfarin Sodium	31	3.5	3.5
Blinatumomab	7	3.5	3.5
Memantine	9	3.4	3.4
Memantine Hydrochloride	9	3.4	3.4
Bortezomib	58	3.4	3.4
Daptomycin	6	3.3	3.3
Vincristine Sulfate	19	3.3	3.3
Atezolizumab	25	3.3	3.3
Mercaptopurine	11	3.3	3.3
Cefepime	9	3.2	3.2
Phenytoin	13	3.2	3.2
Loratadine	65	3.1	3.1
Sofosbuvir	12	3.1	3.1
Azacitidine For	11	3.1	3.1
Regorafenib	7	3.1	3.1
Atorvastatin Calcium, Film Coated	42	3.1	3.1
Emtricitabine And Tenofovir Disoproxil Fumarate	27	3.1	3.1
Dasatinib	22	3.1	3.1
Ixazomib	17	3.0	3.0
Dexamethasone 1.5 Mg	168	3.0	3.0
Dexamethasone	170	3.0	3.0
Vemurafenib	7	3.0	3.0
Pioglitazone	25	3.0	3.0
Imatinib Mesylate	16	3.0	3.0
Ifosfamide	12	2.9	2.9
Tenofovir Disoproxil Fumarate	18	2.8	2.8
Oxaliplatin	40	2.8	2.8
Prochlorperazine	15	2.8	2.8
Clobazam	13	2.7	2.7
Carboxymethylcellulose Sodium	5	2.7	2.7
Cladribine	5	2.7	2.7
Encorafenib	5	2.6	2.6
Daratumumab	20	2.6	2.6
Pembrolizumab	52	2.6	2.6
Ipilimumab	21	2.5	2.5
Paclitaxel (Aibumin-Bound)	39	2.5	2.5
Carboplatin	60	2.5	2.5
Dabrafenib	10	2.4	2.4
Gemcitabine Hydrochloride	25	2.4	2.4
Ticagrelor	15	2.4	2.4
Icosapent Ethyl	4	2.4	2.4
Paclitaxel	46	2.4	2.4
Selexipag	12	2.4	2.4
Thalidomide	17	2.4	2.4
Tenofovir Disoproxil Fumarate Tablets	4	2.4	2.4
Canakinumab	5	2.4	2.4
Brinzolamide	4	2.4	2.4
Gemcitabine	18	2.4	2.4
Abemaciclib	9	2.3	2.3
Mometasone Furoate And Formoterol Fumarate Dihydrate	7	2.3	2.3
Pemetrexed	9	2.2	2.2
Docetaxel Anhydrous	28	2.1	2.1
Docetaxel	28	2.1	2.1
Bevacizumab	51	2.1	2.1
Fexofenadine Hydrochloride	9	2.1	2.1
Acetaminophen, Aspirin (Nsaid) And Caffeine	7	2.1	2.1
Nivolumab	39	2.1	2.1
Suvorexant	5	2.0	2.0
Temozolomide	8	2.0	2.0
Dabigatran Etexilate	28	1.9	1.9
Selinexor	3	1.8	1.8
Vigabatrin	5	1.8	1.8
Acetaminophen, Aspirin, And Caffeine	7	1.7	1.7
Romiplostim	5	1.7	1.7
Trametinib	8	1.7	1.7
Emicizumab	4	1.7	1.7
Crizotinib	4	1.6	1.6
Axitinib	6	1.6	1.6
Abiraterone	4	1.5	1.5
Pomalidomide	30	1.5	1.5
Dabigatran Etexilate Mesylate	21	1.5	1.5
Sacubitril And Valsartan	32	1.4	1.4
Pegfilgrastim	25	1.3	1.3
Lenalidomide	89	1.1	1.1
Ledipasvir And Sofosbuvir	4	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.