Reaction

Derealisation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,111 reports · 57 co-occurring drugs

As of the last recalculation, Derealisation appears in 2,111 FAERS reports alongside 57 co-occurring drug terms. The strongest observed disproportionality signal is PAROXETINE HYDROCHLORIDE HEMIHYDRATE (PRR 30.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Paroxetine Hydrochloride Hemihydrate	97	30.0	30.1
Paroxetine	97	29.4	29.5
Paroxetine Hydrochloride	161	18.8	18.8
Cyclobenzaprine Hydrochloride	17	18.8	18.8
Esketamine Hydrochloride	28	15.7	15.7
Amitriptyline Hydrochloride	27	15.4	15.4
Quetiapine Fumarate	40	13.6	13.6
Venlafaxine	87	12.4	12.5
Diazepam Oral Solution (Concentrate)	107	12.4	12.4
Diazepam Oral	107	12.4	12.4
Sertraline	137	12.2	12.3
Mirtazapine	107	12.1	12.1
Clonazepam	177	11.8	11.8
Quetiapine	208	11.7	11.7
Tramadol Hydrochloride	43	11.5	11.5
Clarithromycin	38	11.1	11.1
Escitslopram	62	10.8	10.8
Venlafaxine Hydrochloride	134	10.6	10.6
Salmeterol Xinafoate	9	10.3	10.3
Diazepam	117	10.0	10.0
Olanzapine	101	9.7	9.7
Escitalopram Oxalate	68	9.5	9.5
Ethyl Alcohol	25	9.2	9.2
Finasteride	52	8.7	8.7
Candesartan	31	8.7	8.7
Fluoxetine Hydrochloride	107	8.7	8.7
Lurasidone Hydrochloride	18	8.5	8.6
Cariprazine	8	8.5	8.5
Ketoprofen	11	8.3	8.3
Ziprasidone	14	7.9	7.9
Isopropyl Alcohol	26	7.7	7.7
Ziprasidone Mesylate	11	7.6	7.6
Fluoxetine	49	7.4	7.4
Olanzapine Pamoate	30	7.3	7.3
Alcohol	27	6.9	6.9
Amphetamine	5	6.0	6.0
Varenicline Tartrate	40	5.0	5.0
Botulinum Toxin Type A	6	4.8	4.8
Diclofenac Potassium, Film Coated	4	4.7	4.7
Diclofenac Potassium Tablets	4	4.7	4.7
Asenapine Maleate	4	4.6	4.6
Lisdexamfetamine Dimesylate	15	4.5	4.5
Vilazodone Hydrochloride	4	4.3	4.3
Atomoxetine Hydrochloride	10	4.2	4.2
Vortioxetine	7	4.1	4.1
Desvenlafaxine Succinate	11	4.0	4.0
Pimavanserin Tartrate	22	4.0	4.0
Nicotine Polacrilex	15	3.9	3.9
Diclofenac Potassium	4	3.7	3.7
Brexpiprazole	6	3.6	3.6
Fremanezumab-Vfrm	4	3.4	3.4
Brivaracetam	3	3.3	3.3
Erenumab-Aooe	18	3.2	3.2
Elexacaftor, Tezacaftor, And Ivacaftor	4	3.2	3.2
Paliperidone	6	2.5	2.5
Tafamidis	3	2.5	2.5
Paliperidone Palmitate	7	2.1	2.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.