Reaction

Skin Induration reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,038 reports · 60 co-occurring drugs

As of the last recalculation, Skin Induration appears in 2,038 FAERS reports alongside 60 co-occurring drug terms. The strongest observed disproportionality signal is EPOETIN ALFA (PRR 195.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Epoetin Alfa	204	195.3	198.8
Paricalcitol	64	47.7	48.0
Iron Sucrose	38	41.5	41.6
Erythropoietin	55	28.1	28.1
Quinine	20	24.0	24.1
Calcitriol Capsules 0.25 Mcg	41	21.3	21.3
Calcitriol Capsules 0.5 Mcg	41	21.3	21.3
Calcitriol	41	21.1	21.1
Regorafenib	23	20.5	20.5
Cinacalcet Hydrochloride	72	16.3	16.3
Sevelamer Carbonate	15	13.4	13.4
Clonidine	64	13.1	13.2
Darbepoetin Alfa	65	12.7	12.7
Metolazone	13	11.9	11.9
Enalapril Maleate	27	11.3	11.3
Valganciclovir	20	10.9	10.9
Valganciclovir Hydrochloride	20	10.9	10.9
Daspone	10	10.5	10.5
Dapsone Gel, 5%	10	10.5	10.5
Diltiazem Hydrochloride	35	10.5	10.5
Sodium Bicarbonate	23	10.2	10.2
Sodium Bicarbonate Injection,	23	10.2	10.2
Nitrofurantoin	16	10.0	10.0
Nitrofurantoin (Monohydrate/Macrocrystals)	16	9.8	9.9
Extended Phenytoin Sodium	16	9.8	9.8
Dapsone	10	9.6	9.6
Olmesartan Medoxomil	33	9.5	9.5
Isosorbide Dinitrate	18	9.5	9.5
Belimumab	29	9.5	9.5
Warfarin Sodium	40	9.0	9.0
Meperidine Hydrochloride	8	8.9	8.9
Nifedipine	40	8.8	8.8
Dicyclomine Hydrochloride	12	8.6	8.7
Colchicine	22	8.6	8.6
Metoroprolol Tartrate	54	8.6	8.6
Amlodipine Besylate	116	8.5	8.5
Rifampin	12	8.4	8.4
Clarithromycin	28	8.4	8.4
Doxazosin Mesylate	29	8.3	8.3
Doxazosin	22	8.1	8.1
Minocycline	9	7.9	7.9
Clobetasol Propionate Ointment Usp, 0.05%	7	7.0	7.0
Clobetasol Propionate	7	6.9	6.9
Sorafenib	14	6.9	6.9
Minoxidil Foam 5% (Womens)	20	6.2	6.2
Pegvaliase-Pqpz	5	6.2	6.2
Asfotase Alfa	6	6.1	6.1
Insulin Human	22	5.7	5.7
Interferon Beta-1B	10	5.3	5.4
Minoxidil	21	4.8	4.8
Isotretinoin	22	4.6	4.6
Adapalene	73	4.2	4.2
Nemolizumab-Ilto	5	4.0	4.0
Interferon Beta-1A	73	4.0	4.0
Glatiramer Acetate	23	4.0	4.0
Peginterferon Beta-1A	5	3.9	3.9
Sulfur	3	3.6	3.6
Salicylic Acid	18	3.5	3.5
Alteplase	5	3.4	3.4
Dupilumab	95	2.1	2.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.