OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Modafinil

1,195 flagged reaction(s) · 128,456 total co-reports · max PRR 159.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Cataplexy 280 159.5 160.9 signal
2 Pre-existing Condition Improved 556 63.1 64.2 signal
3 Periodic Limb Movement Disorder 32 62.0 62.1 signal
4 Narcolepsy 154 58.0 58.3 signal
5 Parasomnia 53 53.4 53.5 signal
6 Sleep-related Eating Disorder 65 48.5 48.6 signal
7 Product Administration Interrupted 454 41.1 41.6 signal
8 Sleep Attacks 28 41.0 41.0 signal
9 Sleep Paralysis 79 37.2 37.3 signal
10 Abnormal Sleep-related Event 64 33.1 33.2 signal
11 Obstructive Sleep Apnoea Syndrome 66 32.4 32.4 signal
12 Snoring 164 29.7 29.8 signal
13 Sleep Apnoea Syndrome 775 27.6 28.2 signal
14 Enuresis 161 27.1 27.2 signal
15 Blood Pressure Measurement 21 22.1 22.1 signal
16 Somnambulism 216 22.1 22.3 signal
17 Postural Orthostatic Tachycardia Syndrome 42 21.6 21.6 signal
18 Secondary Progressive Multiple Sclerosis 48 16.9 17.0 signal
19 Substance Use 38 16.5 16.5 signal
20 Hangover 84 15.9 15.9 signal
21 Cervical Spinal Stenosis 40 15.4 15.5 signal
22 Terminal Insomnia 39 15.0 15.0 signal
23 Jc Polyomavirus Test Positive 26 14.7 14.7 signal
24 Sleep Talking 37 14.4 14.5 signal
25 Hypervigilance 19 13.1 13.1 signal
26 Band Sensation 24 12.5 12.5 signal
27 Sudden Onset Of Sleep 26 12.4 12.4 signal
28 Feeling Drunk 135 12.0 12.1 signal
29 Nasal Septum Deviation 35 11.9 11.9 signal
30 Polycystic Ovaries 27 11.4 11.4 signal
31 Essential Tremor 19 11.3 11.3 signal
32 Neurogenic Bladder 35 11.0 11.0 signal
33 Mitral Valve Prolapse 26 10.3 10.3 signal
34 Complex Regional Pain Syndrome 23 10.2 10.3 signal
35 Impulse-control Disorder 31 10.0 10.0 signal
36 B-lymphocyte Count Decreased 20 9.8 9.8 signal
37 Drug Tolerance 75 9.8 9.8 signal
38 Wisdom Teeth Removal 19 9.7 9.7 signal
39 Post-traumatic Stress Disorder 98 9.7 9.7 signal
40 Major Depression 106 9.6 9.6 signal
41 Multiple Sclerosis 689 9.5 9.7 signal
42 Bruxism 77 9.4 9.5 signal
43 Pathological Gambling 24 9.4 9.4 signal
44 Muscle Spasticity 176 9.4 9.4 signal
45 Bipolar Disorder 153 9.2 9.3 signal
46 Obsessive-compulsive Disorder 112 9.2 9.2 signal
47 Peroneal Nerve Palsy 78 9.1 9.1 signal
48 Hypertonic Bladder 39 9.0 9.0 signal
49 Clumsiness 37 8.9 8.9 signal
50 White Blood Cells Urine Positive 25 8.8 8.9 signal
51 Tonsillectomy 22 8.7 8.7 signal
52 Initial Insomnia 133 8.6 8.7 signal
53 Gastric Bypass 28 8.5 8.5 signal
54 Multiple Sclerosis Relapse 868 8.3 8.5 signal
55 Wrong Dose 30 8.2 8.2 signal
56 Bladder Spasm 23 8.2 8.2 signal
57 Attention Deficit/hyperactivity Disorder 40 8.1 8.1 signal
58 Therapeutic Response Unexpected 550 8.1 8.2 signal
59 Concussion 94 8.0 8.0 signal
60 Slow Speech 29 8.0 8.0 signal
61 Trigeminal Neuralgia 47 7.7 7.7 signal
62 Conversion Disorder 22 7.5 7.5 signal
63 Restless Legs Syndrome 204 7.4 7.4 signal
64 Bipolar I Disorder 24 7.2 7.2 signal
65 Neck Injury 32 7.2 7.2 signal
66 Drug Titration Error 28 7.1 7.1 signal
67 Lyme Disease 35 7.0 7.0 signal
68 Eye Contusion 22 6.9 6.9 signal
69 Bladder Disorder 100 6.6 6.6 signal
70 Hunger 135 6.6 6.6 signal
71 Neck Surgery 23 6.6 6.6 signal
72 Temporomandibular Joint Syndrome 27 6.6 6.6 signal
73 Motion Sickness 19 6.5 6.5 signal
74 Oral Surgery 23 6.5 6.5 signal
75 Vitamin D Deficiency 96 6.5 6.5 signal
76 Autoimmune Thyroiditis 37 6.5 6.5 signal
77 Intervertebral Disc Degeneration 88 6.2 6.2 signal
78 Endometriosis 45 6.2 6.2 signal
79 Adjustment Disorder With Depressed Mood 19 6.2 6.2 signal
80 Spinal Stenosis 38 6.1 6.1 signal
81 Shoulder Operation 39 6.1 6.1 signal
82 Middle Insomnia 170 6.0 6.0 signal
83 Vitamin D Decreased 78 6.0 6.0 signal
84 Nocturia 110 6.0 6.0 signal
85 Back Injury 98 6.0 6.0 signal
86 Intervertebral Disc Protrusion 198 5.9 6.0 signal
87 Ligament Rupture 40 5.9 5.9 signal
88 Tic 49 5.9 5.9 signal
89 Spinal Fusion Surgery 36 5.9 5.9 signal
90 Poor Quality Sleep 191 5.9 5.9 signal
91 Attention Deficit Hyperactivity Disorder 37 5.9 5.9 signal
92 Optic Neuritis 81 5.8 5.9 signal
93 Fibromyalgia 214 5.8 5.8 signal
94 Decreased Interest 52 5.8 5.8 signal
95 Urine Analysis Abnormal 26 5.7 5.7 signal
96 Intervertebral Disc Disorder 37 5.7 5.7 signal
97 Spinal Osteoarthritis 76 5.7 5.7 signal
98 Mania 140 5.6 5.6 signal
99 Surgery 493 5.6 5.7 signal
100 Essential Hypertension 22 5.6 5.6 signal
101 Cartilage Injury 21 5.6 5.6 signal
102 Scoliosis 52 5.5 5.5 signal
103 Autonomic Nervous System Imbalance 24 5.5 5.5 signal
104 Seasonal Allergy 117 5.5 5.5 signal
105 Lumbar Spinal Stenosis 24 5.4 5.4 signal
106 Walking Aid User 54 5.4 5.4 signal
107 Temperature Intolerance 83 5.3 5.4 signal
108 Hysterectomy 70 5.3 5.3 signal
109 Nerve Compression 74 5.3 5.3 signal
110 Spinal Column Stenosis 38 5.2 5.2 signal
111 Hypersensitivity Vasculitis 21 5.2 5.2 signal
112 Balance Disorder 684 5.2 5.3 signal
113 Face Injury 30 5.2 5.2 signal
114 Ankle Fracture 122 5.2 5.2 signal
115 Paranoia 134 5.1 5.1 signal
116 Vitamin B12 Deficiency 31 5.1 5.1 signal
117 Neuralgia 186 5.0 5.1 signal
118 Glucose Tolerance Impaired 45 5.0 5.0 signal
119 Rhinitis Allergic 34 5.0 5.0 signal
120 Meniscus Injury 47 5.0 5.0 signal
121 Hallucinations, Mixed 32 5.0 5.0 signal
122 Spinal Operation 92 5.0 5.0 signal
123 Hypopnoea 26 4.9 4.9 signal
124 Hypersomnia 215 4.9 5.0 signal
125 Incontinence 79 4.9 4.9 signal
126 Nuclear Magnetic Resonance Imaging Abnormal 25 4.9 4.9 signal
127 Apnoea 58 4.9 4.9 signal
128 Blood Sodium Increased 20 4.8 4.9 signal
129 Invasive Ductal Breast Carcinoma 20 4.8 4.8 signal
130 Feeling Jittery 140 4.8 4.8 signal
131 Central Nervous System Lesion 101 4.8 4.8 signal
132 Ligament Sprain 72 4.8 4.8 signal
133 Fibula Fracture 21 4.8 4.8 signal
134 Red Blood Cell Count Increased 20 4.7 4.7 signal
135 Wheelchair User 32 4.7 4.7 signal
136 Micturition Urgency 81 4.7 4.7 signal
137 Suicidal Ideation 654 4.7 4.8 signal
138 Urine Abnormality 32 4.7 4.7 signal
139 Sleep Terror 30 4.7 4.7 signal
140 Urinary Incontinence 211 4.7 4.7 signal
141 Facial Bones Fracture 26 4.7 4.7 signal
142 Logorrhoea 25 4.7 4.7 signal
143 Depression 1,617 4.6 4.8 signal
144 Somnolence 1,418 4.6 4.8 signal
145 Demyelination 29 4.6 4.6 signal
146 Knee Operation 68 4.6 4.6 signal
147 Heart Rate Abnormal 38 4.5 4.5 signal
148 Drug Diversion 39 4.5 4.5 signal
149 Lymphocyte Count Decreased 120 4.5 4.5 signal
150 Hypomania 25 4.5 4.5 signal
151 Affective Disorder 53 4.4 4.4 signal
152 Iron Deficiency 30 4.4 4.4 signal
153 Foot Fracture 127 4.4 4.4 signal
154 Psychotic Disorder 196 4.4 4.4 signal
155 Coordination Abnormal 93 4.3 4.4 signal
156 Urine Odour Abnormal 39 4.3 4.3 signal
157 Abnormal Dreams 182 4.3 4.3 signal
158 Anal Incontinence 58 4.3 4.3 signal
159 Foot Operation 32 4.3 4.3 signal
160 Carpal Tunnel Syndrome 90 4.2 4.2 signal
161 Cognitive Disorder 298 4.2 4.2 signal
162 Nephrolithiasis 293 4.2 4.2 signal
163 Uterine Leiomyoma 47 4.2 4.2 signal
164 Brain Fog 93 4.2 4.2 signal
165 Muscle Strain 55 4.2 4.2 signal
166 Exostosis 58 4.2 4.2 signal
167 Escherichia Urinary Tract Infection 27 4.2 4.2 signal
168 Tachyphrenia 22 4.2 4.2 signal
169 Metabolic Encephalopathy 19 4.2 4.2 signal
170 Migraine 599 4.1 4.2 signal
171 Intentional Dose Omission 172 4.1 4.1 signal
172 Appendicectomy 22 4.1 4.1 signal
173 Hyperlipidaemia 73 4.0 4.0 signal
174 Memory Impairment 837 4.0 4.1 signal
175 Obesity 97 4.0 4.0 signal
176 Intentional Product Use Issue 531 4.0 4.0 signal
177 Craniocerebral Injury 18 3.9 3.9 signal
178 Trismus 31 3.9 3.9 signal
179 Dissociation 45 3.9 3.9 signal
180 Unevaluable Event 449 3.9 3.9 signal
181 Euphoric Mood 61 3.9 3.9 signal
182 Trigger Finger 24 3.9 3.9 signal
183 Sinus Disorder 117 3.9 3.9 signal
184 Panic Attack 215 3.9 3.9 signal
185 Depression Suicidal 20 3.8 3.8 signal
186 Functional Gastrointestinal Disorder 20 3.8 3.8 signal
187 Energy Increased 34 3.8 3.8 signal
188 Electroencephalogram Abnormal 18 3.7 3.7 signal
189 Incoherent 37 3.7 3.7 signal
190 Impaired Gastric Emptying 72 3.7 3.7 signal
191 Impaired Driving Ability 64 3.7 3.7 signal
192 Road Traffic Accident 235 3.7 3.7 signal
193 Benign Prostatic Hyperplasia 29 3.7 3.7 signal
194 Stress 402 3.7 3.7 signal
195 Muscle Twitching 129 3.7 3.7 signal
196 Progressive Multifocal Leukoencephalopathy 46 3.7 3.7 signal
197 Sedation 144 3.6 3.6 signal
198 Joint Injury 118 3.6 3.6 signal
199 Back Disorder 90 3.6 3.6 signal
200 Thinking Abnormal 103 3.6 3.6 signal
201 Delusion 85 3.6 3.6 signal
202 Lymphopenia 77 3.6 3.6 signal
203 Clavicle Fracture 21 3.6 3.6 signal
204 Cholecystectomy 62 3.6 3.6 signal
205 Head Injury 172 3.6 3.6 signal
206 Arthropod Bite 40 3.6 3.6 signal
207 Food Allergy 41 3.6 3.6 signal
208 Wrist Fracture 65 3.6 3.6 signal
209 Hiatus Hernia 70 3.5 3.5 signal
210 Fall 1,791 3.5 3.7 signal
211 Hyperacusis 20 3.5 3.5 signal
212 Sensory Loss 43 3.5 3.5 signal
213 Cardiac Murmur 46 3.5 3.5 signal
214 Hallucination, Auditory 84 3.5 3.5 signal
215 Anxiety 1,501 3.5 3.6 signal
216 Diabetic Neuropathy 26 3.4 3.4 signal
217 Hemiparesis 89 3.4 3.4 signal
218 Disability 103 3.4 3.4 signal
219 Muscle Fatigue 22 3.4 3.4 signal
220 Disturbance In Attention 279 3.4 3.4 signal
221 Dental Caries 57 3.4 3.4 signal
222 Homicidal Ideation 21 3.4 3.4 signal
223 Irritable Bowel Syndrome 110 3.4 3.4 signal
224 Left Ventricular Hypertrophy 22 3.4 3.4 signal
225 Dyskinesia 208 3.4 3.4 signal
226 Joint Dislocation 54 3.4 3.4 signal
227 Activities Of Daily Living Impaired 103 3.4 3.4 signal
228 Faecal Incontinence 25 3.4 3.4 signal
229 Tibia Fracture 24 3.3 3.3 signal
230 Gastroenteritis Viral 92 3.3 3.3 signal
231 Retching 108 3.3 3.3 signal
232 Nightmare 176 3.3 3.3 signal
233 Overweight 27 3.3 3.3 signal
234 Renal Cyst 40 3.3 3.3 signal
235 Onychomycosis 22 3.3 3.3 signal
236 Cerebral Disorder 37 3.3 3.3 signal
237 Thyroid Mass 19 3.3 3.3 signal
238 Macular Oedema 28 3.3 3.3 signal
239 Dysstasia 146 3.3 3.3 signal
240 Rib Fracture 102 3.3 3.3 signal
241 Gait Disturbance 952 3.3 3.3 signal
242 Ataxia 59 3.2 3.2 signal
243 Motor Dysfunction 50 3.2 3.2 signal
244 Grand Mal Convulsion 46 3.2 3.2 signal
245 Knee Arthroplasty 102 3.2 3.2 signal
246 Muscle Tightness 79 3.2 3.2 signal
247 Cystitis 156 3.2 3.2 signal
248 Flushing 496 3.2 3.2 signal
249 Dysgraphia 32 3.2 3.2 signal
250 Sensation Of Heaviness 19 3.2 3.2 signal
251 Autoimmune Disorder 46 3.1 3.2 signal
252 Thyroid Function Test Abnormal 20 3.1 3.1 signal
253 Muscular Weakness 543 3.1 3.2 signal
254 Sensory Disturbance 77 3.1 3.1 signal
255 Cerebral Atrophy 19 3.1 3.1 signal
256 Synovial Cyst 22 3.1 3.1 signal
257 Behaviour Disorder 25 3.1 3.1 signal
258 Gastrooesophageal Reflux Disease 374 3.1 3.1 signal
259 Disorientation 185 3.1 3.1 signal
260 Feeling Abnormal 1,118 3.0 3.1 signal
261 Hepatic Steatosis 86 3.0 3.0 signal
262 Blood Cholesterol Increased 214 3.0 3.0 signal
263 Post Procedural Complication 88 3.0 3.0 signal
264 Hypoaesthesia 685 3.0 3.0 signal
265 Drug Screen Positive 36 3.0 3.0 signal
266 Drug Effect Less Than Expected 64 3.0 3.0 signal
267 Tooth Fracture 50 3.0 3.0 signal
268 Sluggishness 46 3.0 3.0 signal
269 Food Poisoning 24 3.0 3.0 signal
270 Mitral Valve Incompetence 51 3.0 3.0 signal
271 Night Sweats 145 3.0 3.0 signal
272 Rotator Cuff Syndrome 58 2.9 3.0 signal
273 Tooth Extraction 56 2.9 2.9 signal
274 Urinary Tract Infection 763 2.9 3.0 signal
275 Affect Lability 43 2.9 2.9 signal
276 Tremor 739 2.9 3.0 signal
277 Limb Injury 120 2.9 2.9 signal
278 Malabsorption 23 2.9 2.9 signal
279 Abasia 111 2.9 2.9 signal
280 Hypothyroidism 141 2.9 2.9 signal
281 Candidiasis 18 2.9 2.9 signal
282 Lower Limb Fracture 84 2.9 2.9 signal
283 Upper-airway Cough Syndrome 36 2.9 2.9 signal
284 Influenza Like Illness 363 2.9 2.9 signal
285 Personality Change 41 2.9 2.9 signal
286 Kidney Infection 86 2.9 2.9 signal
287 Coeliac Disease 43 2.9 2.9 signal
288 Vein Disorder 22 2.9 2.9 signal
289 Blood Pressure Abnormal 86 2.8 2.8 signal
290 Dysarthria 163 2.8 2.8 signal
291 Blood Cholesterol Abnormal 20 2.8 2.8 signal
292 Spinal Disorder 41 2.8 2.8 signal
293 Sinusitis 443 2.8 2.8 signal
294 Insomnia 1,148 2.8 2.9 signal
295 Blood Pressure Increased 657 2.8 2.8 signal
296 Sciatica 68 2.8 2.8 signal
297 Skin Abrasion 20 2.8 2.8 signal
298 Amnesia 278 2.8 2.8 signal
299 Vertigo 259 2.8 2.8 signal
300 Musculoskeletal Discomfort 73 2.8 2.8 signal
301 Convulsion 246 2.8 2.8 signal
302 Food Craving 21 2.8 2.8 signal
303 Hypertension 896 2.8 2.8 signal
304 Ear Infection 112 2.8 2.8 signal
305 Osteoarthritis 179 2.8 2.8 signal
306 Blood Testosterone Decreased 29 2.8 2.8 signal
307 Osteopenia 64 2.7 2.8 signal
308 Immune Reconstitution Inflammatory Syndrome 21 2.7 2.7 signal
309 Pleurisy 25 2.7 2.7 signal
310 Hypoaesthesia Oral 63 2.7 2.7 signal
311 Anger 142 2.7 2.7 signal
312 Viral Upper Respiratory Tract Infection 20 2.7 2.7 signal
313 Paralysis 60 2.7 2.7 signal
314 Cardiac Flutter 27 2.7 2.7 signal
315 Jaw Disorder 23 2.7 2.7 signal
316 Tooth Disorder 93 2.7 2.7 signal
317 Thirst 74 2.7 2.7 signal
318 Hallucination 311 2.7 2.7 signal
319 Muscle Spasms 761 2.7 2.8 signal
320 Depressed Mood 218 2.7 2.7 signal
321 Peripheral Coldness 57 2.7 2.7 signal
322 Prescribed Overdose 80 2.7 2.7 signal
323 Hypokinesia 60 2.7 2.7 signal
324 Petit Mal Epilepsy 21 2.7 2.7 signal
325 Diplopia 107 2.7 2.7 signal
326 Crying 150 2.7 2.7 signal
327 Hypovolaemia 24 2.7 2.7 signal
328 Aphasia 124 2.7 2.7 signal
329 Bronchitis 304 2.7 2.7 signal
330 Choking 79 2.7 2.7 signal
331 Performance Status Decreased 19 2.7 2.7 signal
332 Screaming 26 2.7 2.7 signal
333 Blood Potassium Decreased 122 2.7 2.7 signal
334 Abnormal Behaviour 160 2.6 2.6 signal
335 Pre-eclampsia 19 2.6 2.6 signal
336 Neck Pain 224 2.6 2.6 signal
337 Limb Operation 19 2.6 2.6 signal
338 Mobility Decreased 285 2.6 2.6 signal
339 Weight Decreased 1,107 2.6 2.7 signal
340 Hormone Level Abnormal 19 2.6 2.6 signal
341 Irritability 237 2.6 2.6 signal
342 Lymphoedema 27 2.6 2.6 signal
343 Upper Limb Fracture 78 2.6 2.6 signal
344 Dry Mouth 315 2.5 2.6 signal
345 Panic Reaction 28 2.5 2.5 signal
346 Urinary Retention 129 2.5 2.5 signal
347 Therapy Cessation 198 2.5 2.5 signal
348 Dermatitis Contact 44 2.5 2.5 signal
349 Varicose Vein 20 2.5 2.5 signal
350 Protein Urine Present 19 2.5 2.5 signal
351 Paraesthesia 603 2.5 2.5 signal
352 Photophobia 71 2.5 2.5 signal
353 Aneurysm 19 2.5 2.5 signal
354 Speech Disorder 199 2.5 2.5 signal
355 Hyperventilation 22 2.5 2.5 signal
356 Fatigue 2,945 2.5 2.6 signal
357 Ovarian Cyst 38 2.5 2.5 signal
358 Nervousness 198 2.5 2.5 signal
359 Condition Aggravated 1,132 2.5 2.5 signal
360 Diverticulum 27 2.5 2.5 signal
361 Formication 26 2.4 2.4 signal
362 Blood Sodium Decreased 70 2.4 2.4 signal
363 Product Taste Abnormal 50 2.4 2.4 signal
364 Cyst 46 2.4 2.4 signal
365 Decubitus Ulcer 30 2.4 2.4 signal
366 Nerve Injury 41 2.4 2.4 signal
367 Emotional Disorder 114 2.4 2.4 signal
368 Oral Disorder 27 2.4 2.4 signal
369 Pollakiuria 153 2.4 2.4 signal
370 Anorexia 48 2.4 2.4 signal
371 Serotonin Syndrome 70 2.4 2.4 signal
372 Limb Discomfort 113 2.4 2.4 signal
373 Tooth Infection 48 2.4 2.4 signal
374 Libido Decreased 45 2.4 2.4 signal
375 Movement Disorder 117 2.4 2.4 signal
376 Agitation 267 2.4 2.4 signal
377 Metabolic Disorder 21 2.4 2.4 signal
378 Social Avoidant Behaviour 21 2.4 2.4 signal
379 Product Substitution Issue 208 2.4 2.4 signal
380 Iron Deficiency Anaemia 33 2.4 2.4 signal
381 Loss Of Consciousness 460 2.3 2.4 signal
382 Brain Injury 36 2.3 2.3 signal
383 Gallbladder Disorder 64 2.3 2.3 signal
384 Mood Altered 97 2.3 2.3 signal
385 Thyroid Disorder 55 2.3 2.3 signal
386 Bursitis 43 2.3 2.3 signal
387 Hernia 68 2.3 2.3 signal
388 Hand Fracture 25 2.3 2.3 signal
389 Tooth Abscess 36 2.3 2.3 signal
390 Sinus Headache 21 2.3 2.3 signal
391 Atelectasis 34 2.3 2.3 signal
392 Restlessness 128 2.3 2.3 signal
393 Frustration Tolerance Decreased 28 2.3 2.3 signal
394 Cellulitis 175 2.3 2.3 signal
395 Cardiomegaly 43 2.3 2.3 signal
396 Spinal Compression Fracture 29 2.3 2.3 signal
397 Cardiomyopathy 51 2.3 2.3 signal
398 Facial Paralysis 29 2.2 2.2 signal
399 Tricuspid Valve Incompetence 27 2.2 2.2 signal
400 Sinus Congestion 46 2.2 2.2 signal
401 Blindness Transient 25 2.2 2.2 signal
402 Hyperaesthesia 28 2.2 2.2 signal
403 Confusional State 548 2.2 2.2 signal
404 Blepharospasm 21 2.2 2.2 signal
405 Drug Abuser 21 2.2 2.2 signal
406 Aphonia 47 2.2 2.2 signal
407 Respiration Abnormal 23 2.2 2.2 signal
408 Accident 40 2.2 2.2 signal
409 Blood Magnesium Decreased 29 2.2 2.2 signal
410 Weight Fluctuation 35 2.2 2.2 signal
411 Nasal Dryness 21 2.2 2.2 signal
412 Tinnitus 154 2.2 2.2 signal
413 Hyperhidrosis 431 2.2 2.2 signal
414 Brain Oedema 42 2.2 2.2 signal
415 Toothache 60 2.2 2.2 signal
416 Prescribed Underdose 66 2.2 2.2 signal
417 Transient Ischaemic Attack 112 2.2 2.2 signal
418 Psychomotor Hyperactivity 55 2.2 2.2 signal
419 Electrocardiogram Abnormal 26 2.2 2.2 signal
420 Delirium 114 2.2 2.2 signal
421 Treatment Noncompliance 179 2.2 2.2 signal
422 Malignant Melanoma 44 2.1 2.1 signal
423 Tension 20 2.1 2.1 signal
424 Choking Sensation 18 2.1 2.1 signal
425 Scar 56 2.1 2.1 signal
426 Emphysema 33 2.1 2.1 signal
427 Facial Pain 29 2.1 2.1 signal
428 Mental Status Changes 90 2.1 2.1 signal
429 Loss Of Personal Independence In Daily Activities 152 2.1 2.1 signal
430 Bradyphrenia 21 2.1 2.1 signal
431 Sleep Disorder 223 2.1 2.1 signal
432 Ventricular Extrasystoles 33 2.1 2.1 signal
433 Staphylococcal Infection 105 2.1 2.1 signal
434 Sexual Dysfunction 37 2.1 2.1 signal
435 Apathy 46 2.1 2.1 signal
436 Arthritis 249 2.1 2.1 signal
437 Diabetes Mellitus 242 2.1 2.1 signal
438 Tenderness 33 2.1 2.1 signal
439 Suicide Attempt 192 2.1 2.1 signal
440 Drug Interaction 501 2.1 2.1 signal
441 Intentional Underdose 23 2.1 2.1 signal
442 Malnutrition 35 2.1 2.1 signal
443 Heart Rate Decreased 111 2.1 2.1 signal
444 Laceration 30 2.1 2.1 signal
445 Basal Cell Carcinoma 49 2.1 2.1 signal
446 Supraventricular Tachycardia 30 2.1 2.1 signal
447 Breast Mass 21 2.0 2.0 signal
448 Low Density Lipoprotein Increased 24 2.0 2.0 signal
449 Cold Sweat 55 2.0 2.0 signal
450 Immune System Disorder 41 2.0 2.0 signal
451 Economic Problem 48 2.0 2.0 signal
452 Type 2 Diabetes Mellitus 105 2.0 2.0 signal
453 Upper Respiratory Tract Infection 143 2.0 2.0 signal
454 Hallucination, Visual 65 2.0 2.0 signal
455 Mental Disorder 135 2.0 2.0 signal
456 Muscle Rigidity 37 2.0 2.0 signal
457 Heart Rate Increased 306 2.0 2.0 signal
458 Tardive Dyskinesia 88 2.0 2.0 signal
459 Musculoskeletal Disorder 59 2.0 2.0 signal
460 Akathisia 42 2.0 2.0 signal
461 Arteriosclerosis 29 2.0 2.0 signal
462 Appetite Disorder 20 2.0 2.0 signal
463 Eye Movement Disorder 21 2.0 2.0 signal
464 Paraesthesia Oral 44 2.0 2.0 signal
465 Palpitations 358 2.0 2.0 signal
466 Multiple Allergies 24 2.0 2.0 signal
467 Skin Laceration 33 2.0 2.0 no signal
468 Drug Effect Decreased 166 2.0 2.0 no signal
469 Muscle Atrophy 38 2.0 2.0 no signal
470 Tendonitis 47 2.0 2.0 no signal
471 Contusion 290 2.0 2.0 no signal
472 Nasopharyngitis 557 2.0 2.0 no signal
473 Flank Pain 28 2.0 2.0 no signal
474 Blood Triglycerides Increased 53 2.0 2.0 no signal
475 Headache 1,871 2.0 2.0 no signal
476 Osteoporosis 123 2.0 2.0 no signal
477 Influenza 333 1.9 2.0 no signal
478 Coronary Artery Occlusion 41 1.9 1.9 no signal
479 Mental Impairment 72 1.9 1.9 no signal
480 Withdrawal Syndrome 125 1.9 1.9 no signal
481 Lethargy 170 1.9 1.9 no signal
482 Ear Discomfort 30 1.9 1.9 no signal
483 Polyuria 24 1.9 1.9 no signal
484 Back Pain 676 1.9 1.9 no signal
485 Appendicitis 27 1.9 1.9 no signal
486 Herpes Zoster 167 1.9 1.9 no signal
487 Drug Use Disorder 24 1.9 1.9 no signal
488 Seizure 332 1.9 1.9 no signal
489 Therapeutic Response Decreased 174 1.9 1.9 no signal
490 Blood Iron Decreased 34 1.9 1.9 no signal
491 Abortion Spontaneous 116 1.9 1.9 no signal
492 Dysuria 106 1.9 1.9 no signal
493 Asthenia 1,079 1.9 1.9 no signal
494 Defaecation Urgency 20 1.9 1.9 no signal
495 Feeling Hot 176 1.9 1.9 no signal
496 Pharyngitis Streptococcal 31 1.9 1.9 no signal
497 Vision Blurred 391 1.9 1.9 no signal
498 Rhinitis 23 1.9 1.9 no signal
499 Immunodeficiency 42 1.9 1.9 no signal
500 Nausea 2,248 1.9 1.9 no signal
501 Chronic Obstructive Pulmonary Disease 148 1.9 1.9 no signal
502 Post Procedural Infection 23 1.9 1.9 no signal
503 Muscle Disorder 23 1.8 1.8 no signal
504 Dizziness 1,405 1.8 1.9 no signal
505 Neuropathy Peripheral 266 1.8 1.8 no signal
506 Asthma 314 1.8 1.8 no signal
507 Foot Deformity 31 1.8 1.8 no signal
508 Hypotonia 28 1.8 1.8 no signal
509 Aggression 140 1.8 1.8 no signal
510 Parosmia 21 1.8 1.8 no signal
511 Visual Field Defect 20 1.8 1.8 no signal
512 Weight Increased 617 1.8 1.8 no signal
513 Decreased Immune Responsiveness 27 1.8 1.8 no signal
514 Cholelithiasis 90 1.8 1.8 no signal
515 Blood Pressure Fluctuation 66 1.8 1.8 no signal
516 Bedridden 36 1.8 1.8 no signal
517 Laboratory Test Abnormal 80 1.8 1.8 no signal
518 Scratch 28 1.8 1.8 no signal
519 Feeling Cold 75 1.8 1.8 no signal
520 Skin Infection 30 1.8 1.8 no signal
521 Gastrointestinal Infection 24 1.8 1.8 no signal
522 Depressed Level Of Consciousness 106 1.8 1.8 no signal
523 Eye Pain 147 1.7 1.7 no signal
524 Musculoskeletal Stiffness 233 1.7 1.7 no signal
525 Gingival Pain 21 1.7 1.7 no signal
526 Gastritis 69 1.7 1.7 no signal
527 Pulmonary Mass 39 1.7 1.7 no signal
528 Haemorrhoids 51 1.7 1.7 no signal
529 Increased Appetite 49 1.7 1.7 no signal
530 Increased Tendency To Bruise 24 1.7 1.7 no signal
531 Blood Thyroid Stimulating Hormone Increased 24 1.7 1.7 no signal
532 Aspiration 28 1.7 1.7 no signal
533 Exposure During Pregnancy 160 1.7 1.7 no signal
534 Psychiatric Symptom 19 1.7 1.7 no signal
535 Mood Swings 82 1.7 1.7 no signal
536 Inadequate Analgesia 22 1.7 1.7 no signal
537 Eye Disorder 84 1.7 1.7 no signal
538 Abdominal Discomfort 428 1.7 1.7 no signal
539 Fungal Infection 85 1.7 1.7 no signal
540 Sinus Tachycardia 36 1.7 1.7 no signal
541 Myasthenia Gravis 20 1.7 1.7 no signal
542 Burning Sensation 178 1.7 1.7 no signal
543 Drug Toxicity 35 1.7 1.7 no signal
544 Neutrophil Count Increased 26 1.7 1.7 no signal
545 Inappropriate Schedule Of Drug Administration 182 1.6 1.7 no signal
546 Hot Flush 190 1.6 1.7 no signal
547 General Symptom 19 1.6 1.6 no signal
548 Illness 253 1.6 1.7 no signal
549 Dystonia 49 1.6 1.6 no signal
550 Myoclonus 30 1.6 1.6 no signal
551 Stevens-johnson Syndrome 56 1.6 1.6 no signal
552 Haematocrit Decreased 50 1.6 1.6 no signal
553 Mydriasis 32 1.6 1.6 no signal
554 Extra Dose Administered 99 1.6 1.6 no signal
555 Eating Disorder 53 1.6 1.6 no signal
556 White Blood Cell Count Increased 95 1.6 1.6 no signal
557 Dyspepsia 242 1.6 1.6 no signal
558 Gastrointestinal Pain 27 1.6 1.6 no signal
559 Chest Pain 457 1.6 1.6 no signal
560 Parkinsonism 24 1.6 1.6 no signal
561 Coronary Artery Disease 75 1.6 1.6 no signal
562 Photosensitivity Reaction 40 1.6 1.6 no signal
563 Mass 34 1.6 1.6 no signal
564 Covid-19 428 1.6 1.6 no signal
565 Oral Herpes 47 1.6 1.6 no signal
566 Hepatic Enzyme Increased 164 1.6 1.6 no signal
567 Blood Pressure Decreased 160 1.6 1.6 no signal
568 Unresponsive To Stimuli 62 1.6 1.6 no signal
569 Dry Eye 116 1.6 1.6 no signal
570 Retinal Detachment 22 1.6 1.6 no signal
571 Blood Calcium Increased 21 1.6 1.6 no signal
572 Gait Inability 79 1.6 1.6 no signal
573 Bacteraemia 28 1.6 1.6 no signal
574 Leukocytosis 43 1.6 1.6 no signal
575 Poisoning 30 1.6 1.6 no signal
576 Mouth Ulceration 50 1.6 1.6 no signal
577 Dehydration 317 1.6 1.6 no signal
578 Drug Prescribing Error 46 1.5 1.5 no signal
579 Drug Hypersensitivity 458 1.5 1.5 no signal
580 Nasal Congestion 138 1.5 1.5 no signal
581 Localised Infection 57 1.5 1.5 no signal
582 Aortic Aneurysm 18 1.5 1.5 no signal
583 Gastrointestinal Disorder 207 1.5 1.5 no signal
584 Substance Abuse 19 1.5 1.5 no signal
585 Chest Discomfort 237 1.5 1.5 no signal
586 Decreased Appetite 538 1.5 1.5 no signal
587 Sars-cov-2 Test Positive 31 1.5 1.5 no signal
588 Product Preparation Error 48 1.5 1.5 no signal
589 Ear Pain 45 1.5 1.5 no signal
590 Skin Disorder 77 1.5 1.5 no signal
591 Arthropathy 129 1.5 1.5 no signal
592 Pain In Extremity 682 1.5 1.5 no signal
593 Clostridium Difficile Infection 50 1.5 1.5 no signal
594 Laryngitis 25 1.5 1.5 no signal
595 Orthostatic Hypotension 40 1.5 1.5 no signal
596 Heart Rate Irregular 52 1.5 1.5 no signal
597 Skin Reaction 32 1.5 1.5 no signal
598 Pregnancy 46 1.5 1.5 no signal
599 Oedema 123 1.5 1.5 no signal
600 Blindness Unilateral 32 1.5 1.5 no signal
601 Musculoskeletal Pain 120 1.5 1.5 no signal
602 Dysphagia 215 1.5 1.5 no signal
603 Deep Vein Thrombosis 148 1.5 1.5 no signal
604 Osteomyelitis 41 1.5 1.5 no signal
605 Dysphonia 132 1.5 1.5 no signal
606 Musculoskeletal Chest Pain 35 1.5 1.5 no signal
607 Viral Infection 75 1.5 1.5 no signal
608 Visual Impairment 276 1.5 1.5 no signal
609 Hypersensitivity 415 1.5 1.5 no signal
610 Hip Arthroplasty 34 1.5 1.5 no signal
611 Injury 158 1.5 1.5 no signal
612 Therapeutic Product Effect Decreased 99 1.5 1.5 no signal
613 Oropharyngeal Pain 206 1.5 1.5 no signal
614 Tachycardia 197 1.4 1.5 no signal
615 Lupus-like Syndrome 20 1.4 1.4 no signal
616 Vomiting 1,038 1.4 1.5 no signal
617 Nervous System Disorder 69 1.4 1.4 no signal
618 Ulcer 35 1.4 1.4 no signal
619 Constipation 475 1.4 1.4 no signal
620 Oesophagitis 24 1.4 1.4 no signal
621 No Therapeutic Response 27 1.4 1.4 no signal
622 Grip Strength Decreased 19 1.4 1.4 no signal
623 Urosepsis 20 1.4 1.4 no signal
624 Encephalopathy 53 1.4 1.4 no signal
625 Head Discomfort 38 1.4 1.4 no signal
626 Spinal Fracture 43 1.4 1.4 no signal
627 Insurance Issue 32 1.4 1.4 no signal
628 Blood Urine Present 41 1.4 1.4 no signal
629 Drug Intolerance 207 1.4 1.4 no signal
630 Visual Acuity Reduced 72 1.4 1.4 no signal
631 Body Temperature Increased 44 1.4 1.4 no signal
632 Impaired Work Ability 46 1.4 1.4 no signal
633 Eye Infection 24 1.4 1.4 no signal
634 Syncope 214 1.4 1.4 no signal
635 Joint Stiffness 56 1.4 1.4 no signal
636 Oedema Peripheral 261 1.4 1.4 no signal
637 Body Height Decreased 23 1.4 1.4 no signal
638 Hepatomegaly 21 1.4 1.4 no signal
639 Gastric Disorder 74 1.4 1.4 no signal
640 Bone Disorder 39 1.4 1.4 no signal
641 Respiratory Depression 26 1.4 1.4 no signal
642 Petechiae 22 1.4 1.4 no signal
643 Swelling 197 1.4 1.4 no signal
644 Fluid Retention 107 1.4 1.4 no signal
645 Chills 247 1.4 1.4 no signal
646 Tendon Rupture 26 1.4 1.4 no signal
647 Hospitalisation 320 1.4 1.4 no signal
648 Pain 1,292 1.4 1.4 no signal
649 Drug Exposure During Pregnancy 72 1.4 1.4 no signal
650 Injection Site Induration 27 1.4 1.4 no signal
651 Pneumothorax 33 1.4 1.4 no signal
652 Sinus Bradycardia 20 1.3 1.3 no signal
653 Erectile Dysfunction 53 1.3 1.3 no signal
654 Skin Lesion 56 1.3 1.3 no signal
655 Gastric Ulcer 39 1.3 1.3 no signal
656 Gingival Bleeding 28 1.3 1.3 no signal
657 Pneumonia Aspiration 51 1.3 1.3 no signal
658 Caesarean Section 24 1.3 1.3 no signal
659 Pulmonary Congestion 27 1.3 1.3 no signal
660 Small Intestinal Obstruction 25 1.3 1.3 no signal
661 Malaise 894 1.3 1.3 no signal
662 Swelling Face 132 1.3 1.3 no signal
663 Red Blood Cell Count Decreased 58 1.3 1.3 no signal
664 Hip Fracture 65 1.3 1.3 no signal
665 Covid-19 Pneumonia 24 1.3 1.3 no signal
666 Macular Degeneration 24 1.3 1.3 no signal
667 Respiratory Arrest 56 1.3 1.3 no signal
668 Tooth Loss 42 1.3 1.3 no signal
669 Blood Alkaline Phosphatase Increased 50 1.3 1.3 no signal
670 Drug Ineffective For Unapproved Indication 112 1.3 1.3 no signal
671 Gout 36 1.3 1.3 no signal
672 Respiratory Tract Infection 52 1.3 1.3 no signal
673 Salivary Hypersecretion 20 1.3 1.3 no signal
674 Product Dose Omission 132 1.3 1.3 no signal
675 Abdominal Pain Upper 409 1.3 1.3 no signal
676 Rhinorrhoea 128 1.3 1.3 no signal
677 Systemic Lupus Erythematosus 70 1.3 1.3 no signal
678 Lymphadenopathy 70 1.3 1.3 no signal
679 Decreased Activity 21 1.3 1.3 no signal
680 Pulmonary Embolism 187 1.3 1.3 no signal
681 Brain Neoplasm 18 1.3 1.3 no signal
682 Generalised Tonic-clonic Seizure 32 1.3 1.3 no signal
683 Diverticulitis 54 1.3 1.3 no signal
684 Drug Dose Omission 326 1.3 1.3 no signal
685 Hypoxia 68 1.3 1.3 no signal
686 Product Dose Omission Issue 549 1.3 1.3 no signal
687 Blood Test Abnormal 27 1.3 1.3 no signal
688 Intentional Product Misuse 167 1.3 1.3 no signal
689 Electrolyte Imbalance 22 1.2 1.2 no signal
690 Squamous Cell Carcinoma 18 1.2 1.2 no signal
691 Wrong Technique In Product Usage Process 385 1.2 1.2 no signal
692 Pain In Jaw 54 1.2 1.2 no signal
693 Schizophrenia 23 1.2 1.2 no signal
694 Accidental Overdose 69 1.2 1.2 no signal
695 Hypercholesterolaemia 18 1.2 1.2 no signal
696 Alopecia 369 1.2 1.2 no signal
697 Dry Throat 19 1.2 1.2 no signal
698 Deafness 49 1.2 1.2 no signal
699 Eye Haemorrhage 25 1.2 1.2 no signal
700 Oral Pain 42 1.2 1.2 no signal
701 Eyelid Ptosis 19 1.2 1.2 no signal
702 Dementia 52 1.2 1.2 no signal
703 Myalgia 317 1.2 1.2 no signal
704 Helicobacter Infection 19 1.2 1.2 no signal
705 Ejection Fraction Decreased 29 1.2 1.2 no signal
706 Presyncope 45 1.2 1.2 no signal
707 Toxic Epidermal Necrolysis 28 1.2 1.2 no signal
708 Cataract 110 1.2 1.2 no signal
709 Pneumonia 598 1.2 1.2 no signal
710 Vitreous Floaters 18 1.2 1.2 no signal
711 Procedural Pain 51 1.2 1.2 no signal
712 Ankylosing Spondylitis 24 1.2 1.2 no signal
713 Blood Urea Increased 31 1.2 1.2 no signal
714 Peripheral Swelling 282 1.2 1.2 no signal
715 Pulmonary Thrombosis 20 1.2 1.2 no signal
716 Cough 512 1.2 1.2 no signal
717 Acute Respiratory Failure 35 1.2 1.2 no signal
718 Urticaria 304 1.2 1.2 no signal
719 Abscess 29 1.2 1.2 no signal
720 Pulmonary Hypertension 38 1.2 1.2 no signal
721 Drug Abuse 152 1.2 1.2 no signal
722 White Blood Cell Count Decreased 197 1.2 1.2 no signal
723 Deformity 17 1.2 1.2 no signal
724 Throat Irritation 81 1.2 1.2 no signal
725 Thrombosis 146 1.2 1.2 no signal
726 Feeding Disorder 36 1.2 1.2 no signal
727 Hepatitis C 22 1.2 1.2 no signal
728 Candida Infection 30 1.2 1.2 no signal
729 Oral Discomfort 25 1.2 1.2 no signal
730 Bradycardia 95 1.2 1.2 no signal
731 Product Dose Omission In Error 48 1.2 1.2 no signal
732 Arthralgia 740 1.2 1.2 no signal
733 Dysgeusia 133 1.2 1.2 no signal
734 Abdominal Distension 185 1.2 1.2 no signal
735 Hypophagia 45 1.2 1.2 no signal
736 Dizziness Postural 17 1.2 1.2 no signal
737 Oral Candidiasis 23 1.2 1.2 no signal
738 Glaucoma 34 1.2 1.2 no signal
739 Scab 20 1.2 1.2 no signal
740 Atrial Fibrillation 172 1.2 1.2 no signal
741 Cardiac Failure Congestive 143 1.2 1.2 no signal
742 Therapy Change 17 1.2 1.2 no signal
743 Acute Myocardial Infarction 52 1.1 1.1 no signal
744 Injection Site Reaction 120 1.1 1.1 no signal
745 Pancreatitis 92 1.1 1.1 no signal
746 Alanine Aminotransferase Increased 106 1.1 1.1 no signal
747 Arrhythmia 82 1.1 1.1 no signal
748 Completed Suicide 145 1.1 1.1 no signal
749 Frequent Bowel Movements 46 1.1 1.1 no signal
750 Liver Function Test Abnormal 50 1.1 1.1 no signal
751 Spinal Pain 20 1.1 1.1 no signal
752 Impaired Healing 56 1.1 1.1 no signal
753 Throat Tightness 46 1.1 1.1 no signal
754 Dyspnoea 962 1.1 1.1 no signal
755 Fear 46 1.1 1.1 no signal
756 Infection 244 1.1 1.1 no signal
757 Pharyngitis 21 1.1 1.1 no signal
758 Cholecystitis 20 1.1 1.1 no signal
759 Angina Pectoris 48 1.1 1.1 no signal
760 Swollen Tongue 52 1.1 1.1 no signal
761 Ill-defined Disorder 101 1.1 1.1 no signal
762 Flatulence 94 1.1 1.1 no signal
763 Joint Range Of Motion Decreased 22 1.1 1.1 no signal
764 Infusion Site Pain 21 1.1 1.1 no signal
765 Pruritus Generalised 36 1.1 1.1 no signal
766 Local Swelling 29 1.1 1.1 no signal
767 Chromaturia 37 1.1 1.1 no signal
768 Rash Generalised 43 1.1 1.1 no signal
769 Respiratory Tract Congestion 26 1.1 1.1 no signal
770 Discomfort 99 1.1 1.1 no signal
771 Eructation 31 1.1 1.1 no signal
772 Drug Ineffective 2,139 1.1 1.1 no signal
773 Generalised Oedema 20 1.1 1.1 no signal
774 Leukopenia 81 1.1 1.1 no signal
775 Gamma-glutamyltransferase Increased 36 1.1 1.1 no signal
776 Device Related Infection 25 1.1 1.1 no signal
777 Chronic Kidney Disease 124 1.1 1.1 no signal
778 Bacterial Infection 30 1.1 1.1 no signal
779 Body Temperature Decreased 16 1.1 1.1 no signal
780 Sneezing 36 1.1 1.1 no signal
781 Intentional Drug Misuse 34 1.0 1.0 no signal
782 Abnormal Weight Gain 20 1.0 1.0 no signal
783 Aspartate Aminotransferase Increased 85 1.0 1.0 no signal
784 Pyrexia 553 1.0 1.0 no signal
785 Drug Withdrawal Syndrome 140 1.0 1.0 no signal
786 Skin Cancer 34 1.0 1.0 no signal
787 Infusion Related Reaction 104 1.0 1.0 no signal
788 Therapeutic Response Shortened 50 1.0 1.0 no signal
789 Thyroid Cancer 19 1.0 1.0 no signal
790 Anaphylactic Reaction 86 1.0 1.0 no signal
791 Wound 43 1.0 1.0 no signal
792 Eye Swelling 57 1.0 1.0 no signal
793 Eyelid Oedema 18 1.0 1.0 no signal
794 Splenomegaly 18 1.0 1.0 no signal
795 Bronchospasm 22 1.0 1.0 no signal
796 Diarrhoea 986 1.0 1.0 no signal
797 Stomatitis 93 1.0 1.0 no signal
798 Sepsis 170 1.0 1.0 no signal
799 Intestinal Obstruction 57 1.0 1.0 no signal
800 Hyperthyroidism 22 1.0 1.0 no signal
801 Renal Pain 16 1.0 1.0 no signal
802 Ovarian Cancer 14 1.0 1.0 no signal
803 Anhedonia 40 1.0 1.0 no signal
804 Skin Discolouration 69 1.0 1.0 no signal
805 Respiratory Disorder 45 1.0 1.0 no signal
806 Dermatitis 31 1.0 1.0 no signal
807 Hyponatraemia 84 1.0 1.0 no signal
808 Pain Of Skin 40 1.0 1.0 no signal
809 Pharyngeal Oedema 23 1.0 1.0 no signal
810 Pruritus 557 1.0 1.0 no signal
811 Coma 70 1.0 1.0 no signal
812 Hypoacusis 63 1.0 1.0 no signal
813 Pharyngeal Swelling 14 1.0 1.0 no signal
814 Blood Glucose Abnormal 27 1.0 1.0 no signal
815 Secretion Discharge 18 1.0 1.0 no signal
816 Respiratory Distress 40 0.9 0.9 no signal
817 Multiple Fractures 24 0.9 0.9 no signal
818 Lip Swelling 48 0.9 0.9 no signal
819 Hypokalaemia 66 0.9 0.9 no signal
820 Intentional Self-injury 29 0.9 0.9 no signal
821 Breast Cancer 135 0.9 0.9 no signal
822 Meningioma 21 0.9 0.9 no signal
823 Fracture 27 0.9 0.9 no signal
824 Adrenal Insufficiency 17 0.9 0.9 no signal
825 Hypotension 284 0.9 0.9 no signal
826 Cardiac Disorder 133 0.9 0.9 no signal
827 Status Epilepticus 16 0.9 0.9 no signal
828 Renal Disorder 66 0.9 0.9 no signal
829 Wrong Technique In Drug Usage Process 52 0.9 0.9 no signal
830 Injection Site Mass 52 0.9 0.9 no signal
831 Hair Texture Abnormal 19 0.9 0.9 no signal
832 Medication Error 78 0.9 0.9 no signal
833 Glomerular Filtration Rate Decreased 17 0.9 0.9 no signal
834 Blindness 57 0.9 0.9 no signal
835 Intentional Overdose 89 0.9 0.9 no signal
836 Erythema Multiforme 13 0.9 0.9 no signal
837 Myocardial Ischaemia 16 0.9 0.9 no signal
838 Blister 78 0.9 0.9 no signal
839 Rash Pruritic 75 0.9 0.9 no signal
840 Dyspnoea Exertional 52 0.9 0.9 no signal
841 Colitis 52 0.9 0.9 no signal
842 Wound Infection 15 0.9 0.9 no signal
843 Blood Pressure Systolic Increased 27 0.9 0.9 no signal
844 Amenorrhoea 23 0.9 0.9 no signal
845 Dysmenorrhoea 18 0.9 0.9 no signal
846 Epilepsy 42 0.9 0.9 no signal
847 Lacrimation Increased 41 0.9 0.9 no signal
848 Abdominal Pain 319 0.9 0.9 no signal
849 Injection Site Haematoma 20 0.9 0.9 no signal
850 Maternal Exposure During Pregnancy 120 0.9 0.9 no signal
851 Adverse Reaction 18 0.9 0.9 no signal
852 Poor Venous Access 14 0.9 0.9 no signal
853 Skin Ulcer 35 0.9 0.9 no signal
854 Folliculitis 14 0.9 0.9 no signal
855 Menorrhagia 27 0.9 0.9 no signal
856 Red Blood Cell Sedimentation Rate Increased 15 0.9 0.9 no signal
857 Product Prescribing Error 32 0.9 0.9 no signal
858 Product Odour Abnormal 14 0.9 0.9 no signal
859 Rash Erythematous 63 0.9 0.9 no signal
860 Cerebral Haemorrhage 48 0.9 0.9 no signal
861 Quality Of Life Decreased 18 0.9 0.9 no signal
862 Acne 102 0.9 0.9 no signal
863 Proteinuria 25 0.9 0.9 no signal
864 Subdural Haematoma 19 0.9 0.9 no signal
865 Epistaxis 99 0.9 0.9 no signal
866 Clostridium Difficile Colitis 14 0.9 0.9 no signal
867 Productive Cough 62 0.9 0.9 no signal
868 Sudden Death 14 0.9 0.9 no signal
869 Adverse Drug Reaction 117 0.9 0.9 no signal
870 Lung Disorder 64 0.9 0.9 no signal
871 Conjunctivitis 24 0.9 0.9 no signal
872 Inflammation 67 0.9 0.9 no signal
873 Pancreatitis Acute 29 0.8 0.8 no signal
874 Drug Dispensing Error 20 0.8 0.8 no signal
875 Fluid Overload 19 0.8 0.8 no signal
876 Wheezing 76 0.8 0.8 no signal
877 Injection Site Erythema 158 0.8 0.8 no signal
878 Extrapyramidal Disorder 32 0.8 0.8 no signal
879 Eye Discharge 13 0.8 0.8 no signal
880 Lung Infection 20 0.8 0.8 no signal
881 Cardiac Arrest 105 0.8 0.8 no signal
882 Myocardial Infarction 222 0.8 0.8 no signal
883 Rash 545 0.8 0.8 no signal
884 Metastases To Liver 22 0.8 0.8 no signal
885 Hypertensive Crisis 14 0.8 0.8 no signal
886 Cerebrovascular Accident 213 0.8 0.8 no signal
887 Glossodynia 28 0.8 0.8 no signal
888 Intraocular Pressure Increased 16 0.8 0.8 no signal
889 Psoriatic Arthropathy 50 0.8 0.8 no signal
890 Blood Calcium Decreased 14 0.8 0.8 no signal
891 Expired Product Administered 41 0.8 0.8 no signal
892 Gastroenteritis 18 0.8 0.8 no signal
893 Renal Failure Acute 53 0.8 0.8 no signal
894 Haematoma 32 0.8 0.8 no signal
895 Bone Pain 72 0.8 0.8 no signal
896 Nodule 16 0.8 0.8 no signal
897 Blood Glucose Decreased 59 0.8 0.8 no signal
898 Abdominal Pain Lower 31 0.8 0.8 no signal
899 Anaemia 232 0.8 0.8 no signal
900 Pharmaceutical Product Complaint 32 0.8 0.8 no signal
901 Complication Associated With Device 16 0.8 0.8 no signal
902 Pallor 33 0.8 0.8 no signal
903 Rash Macular 42 0.8 0.8 no signal
904 Joint Swelling 145 0.8 0.8 no signal
905 Pleural Effusion 73 0.8 0.8 no signal
906 Ocular Discomfort 13 0.8 0.8 no signal
907 Blood Creatine Phosphokinase Increased 35 0.8 0.8 no signal
908 Madarosis 14 0.8 0.8 no signal
909 Drug Eruption 21 0.8 0.8 no signal
910 Breast Cancer Female 32 0.8 0.8 no signal
911 Product Use Issue 222 0.8 0.8 no signal
912 Injection Site Irritation 15 0.8 0.8 no signal
913 Face Oedema 20 0.8 0.8 no signal
914 Ocular Hyperaemia 55 0.8 0.8 no signal
915 Neuroleptic Malignant Syndrome 14 0.8 0.8 no signal
916 Hepatic Cirrhosis 22 0.8 0.8 no signal
917 Polyneuropathy 14 0.8 0.8 no signal
918 Liver Disorder 52 0.8 0.8 no signal
919 Adverse Event 108 0.8 0.8 no signal
920 Pulmonary Arterial Hypertension 17 0.8 0.8 no signal
921 Abortion Induced 11 0.8 0.8 no signal
922 Oxygen Saturation Decreased 65 0.8 0.8 no signal
923 Respiratory Failure 85 0.8 0.8 no signal
924 Sputum Discoloured 11 0.8 0.8 no signal
925 Altered State Of Consciousness 25 0.8 0.8 no signal
926 Rash Papular 26 0.8 0.8 no signal
927 Glycosylated Haemoglobin Increased 29 0.8 0.8 no signal
928 Incorrect Dose Administered 258 0.7 0.7 no signal
929 Cyanosis 18 0.7 0.7 no signal
930 Colon Cancer 17 0.7 0.7 no signal
931 Metabolic Acidosis 36 0.7 0.7 no signal
932 Hypercalcaemia 14 0.7 0.7 no signal
933 No Adverse Event 201 0.7 0.7 no signal
934 Hypoglycaemia 55 0.7 0.7 no signal
935 Injection Site Discolouration 14 0.7 0.7 no signal
936 Breast Pain 12 0.7 0.7 no signal
937 Dermatitis Allergic 14 0.7 0.7 no signal
938 Ageusia 28 0.7 0.7 no signal
939 Injection Site Bruising 88 0.7 0.7 no signal
940 Anosmia 16 0.7 0.7 no signal
941 Haematemesis 28 0.7 0.7 no signal
942 Pelvic Pain 20 0.7 0.7 no signal
943 Pulmonary Oedema 49 0.7 0.7 no signal
944 Anaphylactic Shock 28 0.7 0.7 no signal
945 Disease Recurrence 52 0.7 0.7 no signal
946 Ventricular Tachycardia 18 0.7 0.7 no signal
947 End Stage Renal Disease 20 0.7 0.7 no signal
948 Inappropriate Antidiuretic Hormone Secretion 11 0.7 0.7 no signal
949 Product Packaging Issue 10 0.7 0.7 no signal
950 Haemoptysis 30 0.7 0.7 no signal
951 Nephropathy 10 0.7 0.7 no signal
952 Skin Fissures 20 0.7 0.7 no signal
953 Osteonecrosis 35 0.7 0.7 no signal
954 Inappropriate Schedule Of Product Administration 186 0.7 0.7 no signal
955 Off Label Use 912 0.7 0.7 no signal
956 Rectal Haemorrhage 45 0.7 0.7 no signal
957 Full Blood Count Abnormal 11 0.7 0.7 no signal
958 Impaired Quality Of Life 15 0.7 0.7 no signal
959 Renal Failure 139 0.7 0.7 no signal
960 Lymphoma 16 0.7 0.7 no signal
961 Femur Fracture 32 0.7 0.7 no signal
962 Vasculitis 12 0.7 0.7 no signal
963 Post Procedural Haemorrhage 12 0.7 0.7 no signal
964 Contraindicated Product Administered 31 0.7 0.7 no signal
965 Product Availability Issue 23 0.7 0.7 no signal
966 Injection Site Rash 31 0.7 0.7 no signal
967 Hospice Care 10 0.7 0.7 no signal
968 Osteonecrosis Of Jaw 25 0.7 0.7 no signal
969 Injection Site Urticaria 24 0.6 0.6 no signal
970 Emotional Distress 119 0.6 0.6 no signal
971 Erythema 201 0.6 0.6 no signal
972 Metastases To Bone 16 0.6 0.6 no signal
973 Hepatitis 25 0.6 0.6 no signal
974 Haemorrhage 102 0.6 0.6 no signal
975 Electrocardiogram Qt Prolonged 35 0.6 0.6 no signal
976 Myocarditis 11 0.6 0.6 no signal
977 Lower Respiratory Tract Infection 44 0.6 0.6 no signal
978 Rebound Effect 11 0.6 0.6 no signal
979 Toxicity To Various Agents 162 0.6 0.6 no signal
980 Coagulopathy 16 0.6 0.6 no signal
981 Uveitis 13 0.6 0.6 no signal
982 Eye Inflammation 9 0.6 0.6 no signal
983 Hereditary Angioedema 10 0.6 0.6 no signal
984 Overdose 206 0.6 0.6 no signal
985 Upper Gastrointestinal Haemorrhage 16 0.6 0.6 no signal
986 General Physical Health Deterioration 108 0.6 0.6 no signal
987 Rheumatoid Arthritis 106 0.6 0.6 no signal
988 Hyperglycaemia 34 0.6 0.6 no signal
989 Eczema 47 0.6 0.6 no signal
990 Haematuria 32 0.6 0.6 no signal
991 Breast Cancer Metastatic 10 0.6 0.6 no signal
992 Metrorrhagia 16 0.6 0.6 no signal
993 Bone Loss 14 0.6 0.6 no signal
994 Platelet Count Increased 12 0.6 0.6 no signal
995 Eye Irritation 51 0.6 0.6 no signal
996 Rhabdomyolysis 38 0.6 0.6 no signal
997 Product Physical Issue 18 0.6 0.6 no signal
998 Drug Administration Error 28 0.6 0.6 no signal
999 Colitis Ulcerative 40 0.6 0.6 no signal
1000 Injection Site Pruritus 59 0.6 0.6 no signal
1001 Haemoglobin Decreased 91 0.6 0.6 no signal
1002 Subarachnoid Haemorrhage 9 0.6 0.6 no signal
1003 Drug Level Decreased 9 0.6 0.6 no signal
1004 Application Site Erythema 23 0.6 0.6 no signal
1005 Pericardial Effusion 20 0.6 0.6 no signal
1006 Blood Potassium Increased 14 0.6 0.6 no signal
1007 Blood Creatinine Increased 56 0.6 0.6 no signal
1008 Neoplasm Malignant 57 0.6 0.6 no signal
1009 Blood Bilirubin Increased 23 0.6 0.6 no signal
1010 Therapeutic Product Effect Incomplete 60 0.6 0.6 no signal
1011 Diabetes Mellitus Inadequate Control 15 0.6 0.6 no signal
1012 Vaginal Haemorrhage 36 0.6 0.6 no signal
1013 Blood Count Abnormal 13 0.6 0.6 no signal
1014 Ischaemic Stroke 15 0.5 0.5 no signal
1015 Product Use Complaint 13 0.5 0.5 no signal
1016 Incorrect Product Administration Duration 17 0.5 0.5 no signal
1017 Skin Haemorrhage 12 0.5 0.5 no signal
1018 Menstruation Irregular 22 0.5 0.5 no signal
1019 Blood Glucose Fluctuation 9 0.5 0.5 no signal
1020 Drug Dependence 133 0.5 0.5 no signal
1021 Inability To Afford Medication 8 0.5 0.5 no signal
1022 Renal Tubular Necrosis 8 0.5 0.5 no signal
1023 Inflammatory Bowel Disease 8 0.5 0.5 no signal
1024 Ileus 10 0.5 0.5 no signal
1025 Tachypnoea 11 0.5 0.5 no signal
1026 Therapy Interrupted 56 0.5 0.5 no signal
1027 Cardio-respiratory Arrest 34 0.5 0.5 no signal
1028 Product Use In Unapproved Indication 197 0.5 0.5 no signal
1029 Intestinal Perforation 9 0.5 0.5 no signal
1030 Lung Neoplasm Malignant 33 0.5 0.5 no signal
1031 Prostatic Specific Antigen Increased 11 0.5 0.5 no signal
1032 Full Blood Count Decreased 16 0.5 0.5 no signal
1033 Acute Respiratory Distress Syndrome 14 0.5 0.5 no signal
1034 Device Occlusion 11 0.5 0.5 no signal
1035 Underdose 57 0.5 0.5 no signal
1036 Skin Burning Sensation 55 0.5 0.5 no signal
1037 Angioedema 34 0.5 0.5 no signal
1038 Hepatic Failure 23 0.5 0.5 no signal
1039 Drug Effect Incomplete 28 0.5 0.5 no signal
1040 Bone Density Decreased 24 0.5 0.5 no signal
1041 Product Quality Issue 102 0.5 0.5 no signal
1042 Treatment Failure 62 0.5 0.5 no signal
1043 Injection Site Pain 228 0.5 0.5 no signal
1044 Diarrhoea Haemorrhagic 7 0.5 0.5 no signal
1045 Acute Kidney Injury 113 0.5 0.5 no signal
1046 Septic Shock 32 0.5 0.5 no signal
1047 Pneumonitis 20 0.5 0.5 no signal
1048 Blood Glucose Increased 139 0.5 0.5 no signal
1049 Skin Exfoliation 61 0.5 0.5 no signal
1050 Mucosal Inflammation 19 0.5 0.5 no signal
1051 Injection Site Nodule 8 0.5 0.5 no signal
1052 Injection Site Warmth 15 0.5 0.5 no signal
1053 Application Site Rash 10 0.5 0.5 no signal
1054 Hypomagnesaemia 10 0.5 0.5 no signal
1055 Lactic Acidosis 23 0.5 0.5 no signal
1056 Obstructive Airways Disorder 8 0.5 0.5 no signal
1057 Ascites 21 0.5 0.5 no signal
1058 Gastrointestinal Haemorrhage 60 0.5 0.5 no signal
1059 Fistula 8 0.5 0.5 no signal
1060 Liver Function Test Increased 15 0.5 0.5 no signal
1061 Product Administration Error 14 0.5 0.5 no signal
1062 Cardiogenic Shock 10 0.5 0.5 no signal
1063 Pneumocystis Jirovecii Pneumonia 7 0.5 0.5 no signal
1064 Taste Disorder 14 0.5 0.5 no signal
1065 Vaginal Discharge 7 0.5 0.5 no signal
1066 Neoplasm 8 0.5 0.5 no signal
1067 Metastases To Lung 8 0.5 0.5 no signal
1068 Neutrophil Count Decreased 28 0.5 0.5 no signal
1069 Myelodysplastic Syndrome 10 0.5 0.5 no signal
1070 Gastric Haemorrhage 8 0.5 0.5 no signal
1071 Product Prescribing Issue 14 0.4 0.4 no signal
1072 Multiple Organ Dysfunction Syndrome 19 0.4 0.4 no signal
1073 Psoriasis 89 0.4 0.4 no signal
1074 Therapy Non-responder 30 0.4 0.4 no signal
1075 Renal Impairment 56 0.4 0.4 no signal
1076 Diabetic Ketoacidosis 16 0.4 0.4 no signal
1077 Eye Pruritus 22 0.4 0.4 no signal
1078 Renal Injury 20 0.4 0.4 no signal
1079 Dry Skin 87 0.4 0.4 no signal
1080 Pericarditis 11 0.4 0.4 no signal
1081 C-reactive Protein Increased 24 0.4 0.4 no signal
1082 Device Failure 10 0.4 0.4 no signal
1083 Drug Administered At Inappropriate Site 7 0.4 0.4 no signal
1084 Application Site Irritation 8 0.4 0.4 no signal
1085 Breast Cancer Stage I 6 0.4 0.4 no signal
1086 Leukaemia 6 0.4 0.4 no signal
1087 Hypocalcaemia 12 0.4 0.4 no signal
1088 Needle Issue 18 0.4 0.4 no signal
1089 Ventricular Fibrillation 7 0.4 0.4 no signal
1090 Syringe Issue 11 0.4 0.4 no signal
1091 Metastases To Central Nervous System 8 0.4 0.4 no signal
1092 Injection Site Swelling 47 0.4 0.4 no signal
1093 Liver Injury 15 0.4 0.4 no signal
1094 Application Site Pruritus 14 0.4 0.4 no signal
1095 Platelet Count Decreased 65 0.4 0.4 no signal
1096 Haemorrhage Intracranial 9 0.4 0.4 no signal
1097 Incorrect Route Of Product Administration 10 0.4 0.4 no signal
1098 Disease Progression 70 0.4 0.4 no signal
1099 Hypothermia 6 0.4 0.4 no signal
1100 Poor Quality Product Administered 6 0.4 0.4 no signal
1101 Cardiovascular Disorder 15 0.4 0.4 no signal
1102 Circulatory Collapse 10 0.4 0.4 no signal
1103 Haematochezia 32 0.4 0.4 no signal
1104 Injection Site Haemorrhage 46 0.4 0.4 no signal
1105 Neurotoxicity 10 0.4 0.4 no signal
1106 Unintended Pregnancy 6 0.4 0.4 no signal
1107 Injection Site Extravasation 7 0.4 0.4 no signal
1108 Hair Colour Changes 7 0.4 0.4 no signal
1109 Foetal Exposure During Pregnancy 45 0.4 0.4 no signal
1110 Product Dispensing Error 12 0.4 0.4 no signal
1111 Pancytopenia 30 0.4 0.4 no signal
1112 Interstitial Lung Disease 26 0.4 0.4 no signal
1113 Thrombocytopenia 60 0.4 0.3 no signal
1114 Hand Deformity 7 0.3 0.3 no signal
1115 Premature Baby 16 0.3 0.3 no signal
1116 Incorrect Drug Administration Duration 15 0.3 0.3 no signal
1117 Posterior Reversible Encephalopathy Syndrome 5 0.3 0.3 no signal
1118 Incorrect Product Storage 7 0.3 0.3 no signal
1119 Product Complaint 13 0.3 0.3 no signal
1120 Device Malfunction 35 0.3 0.3 no signal
1121 Pancreatic Carcinoma 15 0.3 0.3 no signal
1122 Faeces Discoloured 11 0.3 0.3 no signal
1123 Prostate Cancer 41 0.3 0.3 no signal
1124 Melaena 11 0.3 0.3 no signal
1125 Device Leakage 21 0.3 0.3 no signal
1126 Dialysis 7 0.3 0.3 no signal
1127 International Normalised Ratio Increased 14 0.3 0.3 no signal
1128 Injection Site Discomfort 5 0.3 0.3 no signal
1129 Incorrect Route Of Drug Administration 17 0.3 0.3 no signal
1130 Dermatitis Atopic 23 0.3 0.3 no signal
1131 Product Packaging Quantity Issue 5 0.3 0.3 no signal
1132 Neutropenia 62 0.3 0.3 no signal
1133 Transaminases Increased 10 0.3 0.3 no signal
1134 Cerebral Infarction 11 0.3 0.3 no signal
1135 Acute Myeloid Leukaemia 7 0.3 0.3 no signal
1136 Sopor 6 0.3 0.3 no signal
1137 Acute Hepatic Failure 6 0.3 0.3 no signal
1138 Shock 10 0.3 0.3 no signal
1139 Plasma Cell Myeloma 17 0.3 0.3 no signal
1140 Incorrect Dose Administered By Device 11 0.3 0.3 no signal
1141 Hepatic Function Abnormal 16 0.3 0.3 no signal
1142 Poisoning Deliberate 4 0.3 0.3 no signal
1143 Drug Resistance 11 0.3 0.3 no signal
1144 Hepatic Encephalopathy 4 0.3 0.3 no signal
1145 Cardiac Failure 34 0.3 0.3 no signal
1146 Product Adhesion Issue 15 0.3 0.3 no signal
1147 Drug Level Increased 7 0.3 0.3 no signal
1148 Hepatocellular Injury 6 0.3 0.3 no signal
1149 Device Dislocation 18 0.3 0.3 no signal
1150 Renal Cancer 20 0.3 0.3 no signal
1151 Device Issue 36 0.3 0.3 no signal
1152 Death 354 0.3 0.3 no signal
1153 Jaundice 11 0.3 0.3 no signal
1154 Rash Maculo-papular 9 0.3 0.3 no signal
1155 Embedded Device 4 0.3 0.3 no signal
1156 Eosinophilia 7 0.3 0.3 no signal
1157 Exposure Via Skin Contact 9 0.3 0.3 no signal
1158 Tuberculosis 5 0.3 0.3 no signal
1159 Synovitis 7 0.3 0.3 no signal
1160 Premature Delivery 6 0.2 0.2 no signal
1161 Device Defective 6 0.2 0.2 no signal
1162 Cholestasis 7 0.2 0.2 no signal
1163 Device Breakage 14 0.2 0.2 no signal
1164 Internal Haemorrhage 4 0.2 0.2 no signal
1165 Product Storage Error 30 0.2 0.2 no signal
1166 Peritonitis 7 0.2 0.2 no signal
1167 Accidental Exposure To Product 33 0.2 0.2 no signal
1168 Malignant Neoplasm Progression 33 0.2 0.2 no signal
1169 Application Site Pain 7 0.2 0.2 no signal
1170 Drug Reaction With Eosinophilia And Systemic Symptoms 8 0.2 0.2 no signal
1171 Injury Associated With Device 6 0.2 0.2 no signal
1172 Bone Marrow Failure 6 0.2 0.2 no signal
1173 Gynaecomastia 9 0.2 0.2 no signal
1174 Skeletal Injury 3 0.2 0.2 no signal
1175 Accidental Underdose 4 0.2 0.2 no signal
1176 Skin Irritation 12 0.2 0.2 no signal
1177 Palmar-plantar Erythrodysaesthesia Syndrome 6 0.2 0.2 no signal
1178 Cytomegalovirus Infection 4 0.2 0.2 no signal
1179 Device Mechanical Issue 3 0.2 0.2 no signal
1180 Device Delivery System Issue 6 0.1 0.1 no signal
1181 Dependence 12 0.1 0.1 no signal
1182 Drug Effective For Unapproved Indication 6 0.1 0.1 no signal
1183 Wrong Technique In Device Usage Process 9 0.1 0.1 no signal
1184 Circumstance Or Information Capable Of Leading To Medication Error 6 0.1 0.1 no signal
1185 Complication Of Device Removal 3 0.1 0.1 no signal
1186 Device Use Issue 3 0.1 0.1 no signal
1187 Bladder Cancer 10 0.1 0.1 no signal
1188 Product Administered At Inappropriate Site 3 0.1 0.1 no signal
1189 Complication Of Device Insertion 3 0.1 0.1 no signal
1190 Gastric Cancer 4 0.1 0.1 no signal
1191 Device Difficult To Use 10 0.1 0.1 no signal
1192 Drug Dose Omission By Device 9 0.1 0.1 no signal
1193 Oesophageal Carcinoma 3 0.1 0.1 no signal
1194 Colorectal Cancer 3 0.0 0.0 no signal
1195 Device Expulsion 3 0.0 0.0 no signal