Reaction

Somnambulism reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,503 reports · 263 co-occurring drugs

As of the last recalculation, Somnambulism appears in 6,503 FAERS reports alongside 263 co-occurring drug terms. The strongest observed disproportionality signal is SODIUM OXYBATE (PRR 62.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Sodium Oxybate	1,083	62.9	63.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	154	58.6	59.7
Zolpidem Tartrate	1,494	45.6	46.1
Suvorexant	141	35.6	35.9
Armodafinil	212	33.2	33.6
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	275	26.0	26.2
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	288	23.2	23.4
Modafinil	216	22.1	22.3
Buspirone Hydrochloride	45	13.1	13.2
Ethyl Alcohol	106	12.7	12.7
Methylphenidate Hydrochloride	222	12.4	12.4
Eszopiclone	84	10.7	10.7
Isopropyl Alcohol	107	10.3	10.3
Asenapine Maleate	27	10.0	10.0
Doxepin Hydrochloride	39	9.9	10.0
Cariprazine	27	9.3	9.3
Alcohol	111	9.3	9.3
Doxepin	29	9.2	9.2
Sumatriptan Succinate	71	9.1	9.1
Varenicline Tartrate	216	8.9	8.9
Pramipexole	42	8.8	8.8
Ziprasidone	48	8.8	8.8
Temazepam	99	8.5	8.5
Lisdexamfetamine Dimesylate	85	8.3	8.4
Methylphenidate	71	7.9	7.9
Ziprasidone Mesylate	34	7.7	7.7
Rasagiline Mesylate	25	7.2	7.2
Buprenorphine Hydrochloride, Naloxone Hydrochloride	53	7.1	7.1
Quetiapine	403	7.1	7.1
Montelukast	181	7.1	7.1
Lithium Carbonate	37	7.0	7.0
Rizatriptan Benzoate	22	6.9	7.0
Lubiprostone	20	6.8	6.8
Butalbital, Acetaminophen, And Caffeine	22	6.6	6.6
Vilazodone Hydrochloride	19	6.6	6.6
Topiramate	186	6.5	6.6
Lurasidone Hydrochloride	42	6.5	6.5
Quetiapine Fumarate	58	6.3	6.3
Olanzapine Pamoate	80	6.3	6.3
Guanfacine	15	6.1	6.1
Carisoprodol	36	6.1	6.1
Montelukast Sodium	223	6.0	6.0
Melatonin	98	5.8	5.8
Olanzapine	189	5.8	5.8
Sumatriptan	67	5.7	5.7
Venlafaxine Hydrochloride	225	5.6	5.6
Hyoscyamine Sulfate	16	5.6	5.6
Clonazepam	267	5.5	5.5
Tizanidine Hydrochloride	31	5.5	5.5
Methocarbamol	38	5.4	5.4
Brexpiprazole	27	5.2	5.2
Meperidine Hydrochloride	15	5.2	5.2
Oxycodone And Acetaminophen Tablets	19	5.1	5.1
Testosterone Cypionate	14	5.0	5.0
Bupropion Hydrochloride	152	5.0	5.0
Amantadine	24	5.0	5.0
Mometasone	28	4.9	4.9
Fluoxetine Hydrochloride	190	4.9	4.9
Ropinirole	23	4.8	4.8
Escitalopram	202	4.7	4.7
Venlafaxine	104	4.7	4.7
Aripiprazole	173	4.6	4.6
Sertraline Hydrochloride	166	4.6	4.6
Diazepam	170	4.6	4.6
Cetirizine Hcl	13	4.5	4.5
Cyclobenzaprine	70	4.5	4.5
Aripiprazole Oral	58	4.5	4.5
Aripiprazole Orally Disintegrating	58	4.5	4.5
Fexofenadine Hydrochloride	30	4.4	4.4
Liothyronine Sodium	12	4.4	4.4
Fluticasone Propionate Nasal	41	4.4	4.4
Lithium	34	4.3	4.3
Lithium Bromatum	34	4.3	4.3
Meclizine	22	4.3	4.3
Divalproex Sodium	62	4.3	4.3
Cyclobenzaprine Hydrochloride	12	4.3	4.3
Dicyclomine Hydrochloride	19	4.3	4.3
Meclizine Hcl 12.5Mg	18	4.2	4.2
Meclizine Hcl 25Mg	18	4.2	4.2
Meclizine Hcl 12.5 Mg	18	4.2	4.2
Meclizine Hcl 25 Mg	18	4.2	4.2
Methocarbamol Tablets	22	4.2	4.2
Rotigotine	19	4.2	4.2
Duloxetine Hydrochloride	237	4.2	4.2
Promethazine Hydrochloride	24	4.1	4.1
Levocetirizine Dihydrochloride	31	4.1	4.1
Cetirizine Hydrochloride Allergy	39	4.1	4.1
Cetirizine Hydrochloride Tablets	39	4.1	4.1
Loratadine Oral	63	4.1	4.1
Meclizine Hydrochloride	25	4.1	4.1
Primidone	13	4.1	4.1
Alprazolam	255	4.1	4.1
Propranolol Hydrochloride	90	4.0	4.0
Lamotrigine	163	4.0	4.0
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	38	4.0	4.0
Diazepam Oral Solution (Concentrate)	110	4.0	4.0
Diazepam Oral	110	4.0	4.0
Mirtazapine	113	4.0	4.0
Esomeprazole Magnesium Capsule, Delayed Release	18	4.0	4.0
Esomeprazole Magnesium Delayed Release Capsules	18	4.0	4.0
Esomeprazole Magnesium Dihydrate	18	4.0	4.0
Cetirizine	94	3.9	3.9
Rabeprazole	27	3.9	3.9
Amphetamine	10	3.9	3.9
Citalopram	157	3.7	3.7
Benzonatate	19	3.7	3.7
Escitslopram	66	3.7	3.7
Oxcarbazepine	37	3.7	3.7
Hydroxyzine Hydrochloride	15	3.7	3.7
Hydroxyzine Hydrochloride Oral	15	3.7	3.7
Oxybutynin Chloride	10	3.7	3.7
Acetaminophen, Aspirin, And Caffeine	24	3.7	3.7
Cyanocobalamin	37	3.6	3.6
Rivastigmine	21	3.6	3.6
Escitalopram Oxalate	79	3.5	3.5
Desvenlafaxine Succinate	29	3.4	3.5
Pimavanserin Tartrate	59	3.4	3.4
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	22	3.4	3.4
Naproxen Sodium, Pseudoephedrine Hydrochloride	22	3.4	3.4
Cetiirizine	45	3.4	3.4
Citalopram Hydrobromide	112	3.4	3.4
Quinine	9	3.4	3.4
Tizanidine	25	3.4	3.4
Cetirizine Hydrochloride	170	3.4	3.4
Docusate Sodium 100Mg	25	3.4	3.4
Fluoxetine	69	3.3	3.3
Alemtuzumab	20	3.3	3.3
Thyroid, Porcine	11	3.3	3.3
Meloxicam	59	3.3	3.3
Guaifenesin	31	3.3	3.3
Methadone Hydrochloride	11	3.3	3.3
Terazosin Hydrochloride	9	3.2	3.2
Acetaminophen, Aspirin (Nsaid) And Caffeine	17	3.2	3.2
Vortioxetine	17	3.2	3.2
Lamotirigine	71	3.2	3.2
Lamotrigine Extended-Release	71	3.2	3.2
Lamotrigine Chewable Dispersible	71	3.2	3.2
Biotin	31	3.2	3.2
Ibuprofen And Diphenhydramine Citrate	23	3.2	3.2
Mometasone Furoate	41	3.2	3.2
Tretinoin	8	3.2	3.2
Testosterone	23	3.2	3.2
Magnesium Oxide	41	3.2	3.2
Gabapentin	341	3.1	3.1
Atomoxetine Hydrochloride	23	3.1	3.1
Loratadine	102	3.1	3.1
Oseltamivir Phosphate	23	3.0	3.0
Ritonavir 100 Mg	14	3.0	3.0
Doxazosin	26	3.0	3.0
Valproate Sodium	19	2.9	2.9
Amitriptyline Hydrochloride	16	2.9	2.9
Sertraline	106	2.9	2.9
Phenytoin	19	2.9	2.9
Carbidopa And Levodopa	43	2.9	2.9
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	45	2.9	2.9
Oxycodone And Acetaminophen	21	2.9	2.9
Lorazepam	159	2.9	2.9
Diphenhydramine Hcl	10	2.9	2.9
Pregabalin	237	2.9	2.9
Metoprolol Succinate Er Tablets	55	2.8	2.8
Valsartan And Hydrochlorothiazide	12	2.8	2.8
Doxyclycline Hyclate	15	2.8	2.8
Progesterone	20	2.8	2.8
Fluticasone Propionate	112	2.8	2.8
Dronabinol	7	2.8	2.8
Losartan Potassium And Hydrochlorothiazide	10	2.8	2.8
Doxazosin Mesylate	31	2.8	2.8
Ezetimibe And Simvastatin	13	2.7	2.7
Bupropion	38	2.7	2.7
Acetylcysteine	8	2.7	2.7
Estradiol Gel 0.1%	38	2.7	2.7
Estradiol Transdermal	38	2.7	2.7
Baclofen	72	2.7	2.7
Valbenazine	21	2.7	2.7
Clonidine	42	2.6	2.6
Multivitamin	41	2.6	2.6
Methadone	35	2.6	2.6
Paroxetine Hydrochloride	74	2.6	2.6
Iron	54	2.6	2.6
Tiotropium Bromide Inhalation Spray	9	2.6	2.6
Nicotine Polacrilex Mini	12	2.6	2.6
Nicotine Polarilex	12	2.6	2.6
Felodipine Extended-Release Tablets	9	2.5	2.5
Felodipine	9	2.5	2.5
Albuterol Sulfate	228	2.5	2.5
Hydroxyzine	37	2.5	2.5
Chlorthalidone	9	2.5	2.5
Duloxetine	53	2.4	2.4
Metoprolol Succinate	65	2.4	2.4
Oxycodone Hydrochloride And Acetaminophen	74	2.4	2.4
Donepezil Hydrochloride	27	2.4	2.4
Fluticasone Propionate And Salmeterol Xinafoate	44	2.4	2.4
Estradiol	63	2.3	2.3
Metformin Hcl	40	2.3	2.3
Fish Oil	65	2.3	2.3
Ibuprofen Capsule	142	2.3	2.3
Ibuprofen Tablet, Film Coated	142	2.3	2.3
Ibupfrofen	142	2.3	2.3
Ibuprofen Tablets Usp, 200Mg	142	2.3	2.3
Ibuprofen Oral	142	2.3	2.3
Ibuprofen Capsules 200 Mg	142	2.3	2.3
Ibuprofen 200 Mg	142	2.3	2.3
Ibuprofen 200Mg	142	2.3	2.3
Oxybutynin	21	2.3	2.3
Efavirenz	8	2.3	2.3
Rimegepant Sulfate	9	2.3	2.3
Loratadine Tablet	37	2.2	2.2
Paroxetine Hydrochloride Hemihydrate	23	2.2	2.2
Ibuprofen	185	2.2	2.2
Haloperidol Lactate	17	2.2	2.2
Zonisamide	10	2.2	2.2
Linaclotide	18	2.2	2.2
Azelastine	12	2.1	2.1
Fexofenadine	11	2.1	2.1
Avapritinib	8	2.1	2.1
Memantine	9	2.1	2.1
Memantine Hydrochloride	9	2.1	2.1
Pravastatin Sodium	13	2.1	2.1
Metoroprolol Tartrate	43	2.1	2.1
Lisinopril And Hydrochlorothiazide Tablets	5	2.0	2.0
Atazanavir	9	2.0	2.0
Derma Foam Excel Hand Sanitizer	5	2.0	2.0
Ethanol	5	2.0	2.0
Tramadol Hydrochloride	23	2.0	2.0
Fremanezumab-Vfrm	7	2.0	2.0
Liraglutide	30	1.9	1.9
Cenobamate	5	1.9	1.9
Naltrexone Hydrochloride And Bupropion Hydrochloride	5	1.9	1.9
Losartan	100	1.8	1.8
Diclofenac Potassium	6	1.8	1.8
Oxycodone	99	1.7	1.7
Buprenorphine	49	1.7	1.7
Ibuprofen Tablets, Coated	22	1.7	1.7
Naproxen Sodium Tablet, Coated	7	1.7	1.7
Naproxen Sodium, Coated Tablets	7	1.7	1.7
Naproxen Sodium 220Mg	7	1.7	1.7
Mometasone Furoate And Formoterol Fumarate Dihydrate	8	1.6	1.6
Nicotine Polacrilex	19	1.6	1.6
Mirabegron	19	1.6	1.6
Naproxen Sodium Tablet	26	1.6	1.6
Elexacaftor, Tezacaftor, And Ivacaftor	6	1.5	1.5
Oxycodone Hydrochloride	101	1.5	1.5
Nicotine	18	1.4	1.4
Hydrocodone Bitartrate And Acetaminophen	25	1.4	1.4
Hydrocodone Bitartrate	19	1.4	1.4
Risperidone	57	1.4	1.4
Morphine Sulfate	51	1.3	1.3
Budesonide, Glycopyrrolate, And Formoterol Fumarate	4	1.2	1.2
Glecaprevir And Pibrentasvir	4	1.2	1.2
Tapentadol Hydrochloride	12	1.1	1.1
Diclofenac Potassium, Film Coated	3	1.1	1.1
Diclofenac Potassium Tablets	3	1.1	1.1
Siponimod	3	1.1	1.1
Teriflunomide	15	1.1	1.1
Emtricitabine And Tenofovir Disoproxil Fumarate	15	1.1	1.1
Ranitidine	62	1.0	1.0
Paliperidone	7	1.0	1.0
Droxidopa	6	0.9	0.9
Pseudoephedrine Hcl	3	0.9	0.9
Galcanezumab-Gnlm	8	0.8	0.8
Paliperidone Palmitate	8	0.8	0.8
Nirmatrelvir And Ritonavir	8	0.5	0.5
Etonogestrel	6	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.