Drug

Promethazine Hydrochloride

1,181 flagged reaction(s) · 99,134 total co-reports · max PRR 200.9

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Human Rhinovirus Test Positive	56	200.9	201.5	signal
2	Viral Test Positive	38	131.3	131.5	signal
3	Pneumonia Haemophilus	50	129.8	130.2	signal
4	Respiratory Syncytial Virus Test Positive	57	99.8	100.1	signal
5	Autoscopy	26	57.8	57.9	signal
6	Biliary Dyskinesia	56	38.3	38.4	signal
7	Cholecystitis Chronic	170	29.1	29.4	signal
8	Mast Cell Activation Syndrome	33	29.0	29.0	signal
9	Gallbladder Injury	47	28.2	28.2	signal
10	Chronic Kidney Disease-mineral And Bone Disorder	26	28.1	28.1	signal
11	Tongue Biting	50	28.1	28.1	signal
12	Infusion Site Discharge	36	24.4	24.4	signal
13	Tongue Injury	19	23.4	23.5	signal
14	Hyperparathyroidism Secondary	45	20.5	20.6	signal
15	Nephrogenic Anaemia	79	19.5	19.6	signal
16	Pancreatitis Chronic	34	16.6	16.7	signal
17	Wrong Patient Received Product	41	16.5	16.5	signal
18	Jugular Vein Thrombosis	25	16.3	16.3	signal
19	Patent Ductus Arteriosus	53	15.3	15.3	signal
20	Thrombophlebitis Superficial	38	14.2	14.2	signal
21	Wound Infection Staphylococcal	20	13.2	13.2	signal
22	Fear Of Disease	20	12.8	12.8	signal
23	Infusion Site Haemorrhage	34	12.0	12.0	signal
24	Mouth Haemorrhage	74	11.6	11.6	signal
25	Jaundice Neonatal	19	11.5	11.5	signal
26	Acute Sinusitis	17	11.3	11.3	signal
27	Atelectasis	94	11.1	11.2	signal
28	Impaired Gastric Emptying	122	11.0	11.0	signal
29	Staphylococcus Test Positive	20	10.8	10.8	signal
30	Infusion Site Bruising	20	10.8	10.8	signal
31	Cholecystitis Acute	53	10.7	10.8	signal
32	Atrial Septal Defect	77	10.5	10.5	signal
33	Haemorrhagic Diathesis	32	10.2	10.3	signal
34	Rebound Acid Hypersecretion	27	10.1	10.1	signal
35	Hereditary Angioedema	92	10.0	10.1	signal
36	Orthopnoea	27	9.7	9.7	signal
37	Device Related Sepsis	17	9.6	9.6	signal
38	Appetite Disorder	54	9.5	9.5	signal
39	Alcohol Poisoning	22	9.5	9.5	signal
40	Supraventricular Extrasystoles	28	9.5	9.5	signal
41	End Stage Renal Disease	151	9.4	9.4	signal
42	Diabetic Neuropathy	40	9.2	9.2	signal
43	Ventricular Septal Defect	46	9.1	9.1	signal
44	Spinal Osteoarthritis	70	9.1	9.1	signal
45	Otitis Media	26	9.0	9.0	signal
46	Psychological Trauma	68	8.9	8.9	signal
47	Device Infusion Issue	19	8.9	8.9	signal
48	Cardiac Murmur	67	8.8	8.8	signal
49	Tricuspid Valve Incompetence	60	8.7	8.7	signal
50	Intervertebral Disc Degeneration	70	8.6	8.6	signal
51	Urinary Hesitation	18	8.6	8.6	signal
52	Catheter Site Pain	19	8.5	8.6	signal
53	Essential Hypertension	19	8.4	8.4	signal
54	Gallbladder Disorder	131	8.4	8.4	signal
55	Heart Disease Congenital	26	8.3	8.3	signal
56	Dysphoria	37	8.3	8.3	signal
57	Economic Problem	110	8.2	8.2	signal
58	Arthritis Infective	33	8.1	8.1	signal
59	Cardiomegaly	88	8.1	8.1	signal
60	Infusion Site Pruritus	22	8.1	8.1	signal
61	Biliary Colic	20	7.9	8.0	signal
62	Vascular Device Infection	31	7.8	7.8	signal
63	Pleuritic Pain	19	7.8	7.8	signal
64	Duodenitis	21	7.8	7.8	signal
65	Flank Pain	64	7.8	7.8	signal
66	Hypoalbuminaemia	52	7.8	7.8	signal
67	Skin Warm	39	7.7	7.7	signal
68	Metabolic Encephalopathy	20	7.6	7.6	signal
69	Bile Duct Stone	21	7.6	7.6	signal
70	Cholecystitis	79	7.6	7.6	signal
71	Non-cardiac Chest Pain	21	7.5	7.5	signal
72	Aortic Valve Incompetence	28	7.5	7.5	signal
73	Left Ventricular Hypertrophy	28	7.5	7.5	signal
74	Thrombophlebitis	23	7.4	7.4	signal
75	Blood Magnesium Decreased	56	7.4	7.4	signal
76	Hiatus Hernia	84	7.4	7.4	signal
77	Talipes	20	7.3	7.4	signal
78	Hypopnoea	22	7.3	7.3	signal
79	Infusion Site Pain	81	7.2	7.3	signal
80	Hypovolaemia	37	7.2	7.2	signal
81	Tenderness	66	7.2	7.2	signal
82	Oesophageal Stenosis	18	7.2	7.2	signal
83	Cholelithiasis	206	7.2	7.2	signal
84	Chronic Sinusitis	23	7.0	7.0	signal
85	Failure To Thrive	31	6.8	6.8	signal
86	Clostridium Difficile Colitis	63	6.8	6.8	signal
87	Maternal Exposure Timing Unspecified	22	6.7	6.8	signal
88	Fibrin D Dimer Increased	21	6.7	6.7	signal
89	Infusion Site Swelling	36	6.7	6.7	signal
90	Brain Natriuretic Peptide Increased	18	6.7	6.7	signal
91	Intervertebral Disc Disorder	25	6.6	6.6	signal
92	Infusion Site Erythema	48	6.6	6.6	signal
93	Renal Failure Chronic	45	6.6	6.6	signal
94	Malnutrition	64	6.6	6.6	signal
95	Azotaemia	23	6.5	6.5	signal
96	Major Depression	42	6.5	6.6	signal
97	Incorrect Drug Administration Rate	24	6.5	6.5	signal
98	Abdominal Adhesions	18	6.5	6.5	signal
99	Candidiasis	23	6.4	6.4	signal
100	Hair Disorder	47	6.4	6.4	signal
101	Rhinitis Allergic	25	6.4	6.4	signal
102	Therapeutic Agent Toxicity	19	6.4	6.4	signal
103	Multiple Allergies	44	6.4	6.4	signal
104	Wound Dehiscence	19	6.4	6.4	signal
105	Hypophosphataemia	41	6.4	6.4	signal
106	Compression Fracture	29	6.4	6.4	signal
107	Cholecystectomy	63	6.3	6.3	signal
108	Upper Respiratory Tract Infection	255	6.3	6.4	signal
109	Hyperlipidaemia	66	6.3	6.3	signal
110	Sinus Tachycardia	78	6.3	6.3	signal
111	Hypokalaemia	249	6.2	6.3	signal
112	Injury	382	6.2	6.3	signal
113	Small Intestinal Obstruction	66	6.1	6.2	signal
114	Humerus Fracture	26	6.1	6.1	signal
115	Staphylococcal Bacteraemia	23	6.0	6.1	signal
116	Snoring	20	6.0	6.0	signal
117	Blood Potassium Decreased	158	6.0	6.0	signal
118	Sleep Apnoea Syndrome	99	5.9	5.9	signal
119	Renal Cyst	41	5.9	5.9	signal
120	Ventricular Extrasystoles	53	5.8	5.8	signal
121	Hair Colour Changes	64	5.8	5.8	signal
122	Migraine	482	5.8	5.9	signal
123	Anhedonia	134	5.8	5.8	signal
124	Abdominal Hernia	23	5.7	5.7	signal
125	Abdominal Tenderness	25	5.7	5.7	signal
126	Endometriosis	24	5.7	5.7	signal
127	Obstruction	20	5.7	5.7	signal
128	Arteriosclerosis Coronary Artery	33	5.7	5.7	signal
129	Bone Lesion	18	5.7	5.7	signal
130	Electrolyte Imbalance	57	5.6	5.7	signal
131	Electrocardiogram Abnormal	39	5.6	5.6	signal
132	Mitral Valve Incompetence	56	5.6	5.7	signal
133	Mental Status Changes	137	5.6	5.7	signal
134	Vitamin D Deficiency	48	5.6	5.6	signal
135	Chronic Kidney Disease	376	5.6	5.7	signal
136	Deep Vein Thrombosis	319	5.6	5.6	signal
137	Breath Sounds Abnormal	24	5.5	5.5	signal
138	Diverticulum	35	5.5	5.5	signal
139	Insurance Issue	72	5.5	5.5	signal
140	Dermatitis Contact	55	5.5	5.5	signal
141	Restless Legs Syndrome	88	5.5	5.5	signal
142	Pharyngeal Swelling	46	5.5	5.5	signal
143	Prothrombin Time Prolonged	29	5.5	5.5	signal
144	Arteriosclerosis	45	5.4	5.4	signal
145	Meningitis Aseptic	21	5.3	5.4	signal
146	Ear Pain	91	5.3	5.4	signal
147	Blood Albumin Decreased	37	5.3	5.3	signal
148	Scoliosis	29	5.3	5.3	signal
149	Intentional Self-injury	93	5.3	5.3	signal
150	Gastroenteritis	67	5.2	5.3	signal
151	Leukocytosis	83	5.2	5.2	signal
152	Acute Respiratory Failure	87	5.2	5.2	signal
153	Gastroenteritis Viral	82	5.2	5.2	signal
154	Madarosis	53	5.2	5.2	signal
155	Lymphocyte Count Decreased	80	5.2	5.2	signal
156	Hair Texture Abnormal	61	5.2	5.2	signal
157	Temperature Intolerance	46	5.1	5.1	signal
158	Oral Pain	101	5.1	5.1	signal
159	Gastrointestinal Infection	40	5.1	5.1	signal
160	Vitamin B12 Deficiency	18	5.1	5.1	signal
161	Ileus	55	5.1	5.1	signal
162	Gastric Infection	17	5.1	5.1	signal
163	Uterine Perforation	38	5.1	5.1	signal
164	Haematocrit Decreased	88	5.0	5.0	signal
165	Lung Infiltration	39	5.0	5.0	signal
166	Dehydration	582	5.0	5.1	signal
167	Diverticulum Intestinal	19	5.0	5.0	signal
168	Ligament Sprain	43	5.0	5.0	signal
169	Sinus Headache	26	5.0	5.0	signal
170	Onychomycosis	19	4.9	4.9	signal
171	Activated Partial Thromboplastin Time Prolonged	22	4.9	4.9	signal
172	Crohn's Disease	30	4.9	4.9	signal
173	Ammonia Increased	22	4.9	4.9	signal
174	Rales	25	4.9	4.9	signal
175	Photophobia	80	4.9	4.9	signal
176	Escherichia Infection	35	4.9	4.9	signal
177	Exostosis	39	4.9	4.9	signal
178	Pancreatic Disorder	21	4.9	4.9	signal
179	Gastritis	112	4.9	4.9	signal
180	Aspiration	46	4.8	4.8	signal
181	Iron Deficiency Anaemia	39	4.8	4.8	signal
182	Intervertebral Disc Protrusion	93	4.8	4.9	signal
183	Congenital Anomaly	33	4.8	4.8	signal
184	Purulent Discharge	18	4.8	4.8	signal
185	Scar	72	4.8	4.8	signal
186	Kidney Infection	82	4.8	4.8	signal
187	Spinal Column Stenosis	20	4.8	4.8	signal
188	Renal Tubular Necrosis	41	4.7	4.8	signal
189	Hypervolaemia	20	4.7	4.8	signal
190	Goitre	17	4.7	4.7	signal
191	Aphagia	20	4.7	4.7	signal
192	Supraventricular Tachycardia	39	4.6	4.7	signal
193	Blood Calcium Decreased	46	4.6	4.7	signal
194	Gingivitis	22	4.6	4.6	signal
195	Dental Caries	45	4.6	4.6	signal
196	Product Administration Interrupted	31	4.6	4.6	signal
197	Premature Labour	23	4.6	4.6	signal
198	Catatonia	21	4.6	4.6	signal
199	Hypoxia	141	4.6	4.6	signal
200	Congestive Cardiomyopathy	17	4.6	4.6	signal
201	Post-traumatic Stress Disorder	27	4.6	4.6	signal
202	Tooth Abscess	41	4.6	4.6	signal
203	Osteopenia	61	4.6	4.6	signal
204	Oral Candidiasis	52	4.6	4.6	signal
205	Haemoglobin Increased	18	4.6	4.6	signal
206	Seasonal Allergy	56	4.5	4.5	signal
207	Diabetes Mellitus Inadequate Control	70	4.5	4.5	signal
208	Uterine Leiomyoma	29	4.5	4.5	signal
209	Dyslipidaemia	20	4.5	4.5	signal
210	Pulmonary Hypertension	82	4.5	4.5	signal
211	Hydronephrosis	29	4.4	4.4	signal
212	Ovarian Cyst	39	4.4	4.4	signal
213	Musculoskeletal Chest Pain	60	4.4	4.4	signal
214	Bronchitis	288	4.4	4.5	signal
215	Fibromyalgia	94	4.4	4.4	signal
216	Retching	82	4.4	4.4	signal
217	Abdominal Abscess	17	4.4	4.4	signal
218	Umbilical Hernia	18	4.4	4.4	signal
219	Pulmonary Mass	57	4.4	4.4	signal
220	Facial Pain	34	4.3	4.3	signal
221	Gastrooesophageal Reflux Disease	305	4.3	4.4	signal
222	Irritable Bowel Syndrome	81	4.3	4.3	signal
223	Vomiting	1,771	4.3	4.7	signal
224	Candida Infection	63	4.3	4.3	signal
225	Multiple Injuries	24	4.3	4.3	signal
226	Hypomagnesaemia	52	4.3	4.3	signal
227	Decreased Interest	22	4.2	4.2	signal
228	Troponin Increased	28	4.2	4.2	signal
229	Osteomyelitis	67	4.2	4.2	signal
230	Neuroleptic Malignant Syndrome	44	4.2	4.2	signal
231	Peripheral Vascular Disorder	19	4.2	4.2	signal
232	Serotonin Syndrome	70	4.2	4.2	signal
233	Pulmonary Embolism	349	4.2	4.2	signal
234	Hypocalcaemia	69	4.2	4.2	signal
235	Somnambulism	24	4.1	4.1	signal
236	Neck Pain	203	4.1	4.2	signal
237	Pulmonary Congestion	48	4.1	4.1	signal
238	Anaphylactic Reaction	199	4.1	4.2	signal
239	Enteritis	23	4.1	4.1	signal
240	Hepatic Steatosis	67	4.1	4.1	signal
241	Pain In Jaw	102	4.1	4.1	signal
242	Bone Disorder	66	4.1	4.1	signal
243	Parkinsonism	35	4.1	4.1	signal
244	Food Poisoning	19	4.1	4.1	signal
245	Oesophagitis	39	4.1	4.1	signal
246	Device Related Infection	55	4.1	4.1	signal
247	Emphysema	36	4.0	4.1	signal
248	Drug Abuser	22	4.0	4.0	signal
249	Respiratory Depression	43	4.0	4.0	signal
250	Respiratory Failure	255	4.0	4.0	signal
251	Ecchymosis	24	4.0	4.0	signal
252	Pre-existing Condition Improved	22	4.0	4.0	signal
253	Drug Hypersensitivity	674	3.9	4.1	signal
254	Paranoia	60	3.9	4.0	signal
255	Blood Alkaline Phosphatase Increased	86	3.9	3.9	signal
256	Blood Sodium Decreased	65	3.9	3.9	signal
257	Weight Fluctuation	36	3.9	3.9	signal
258	Bronchiectasis	23	3.9	3.9	signal
259	Cellulitis	174	3.9	4.0	signal
260	Renal Failure	461	3.9	4.0	signal
261	Apnoea	27	3.9	3.9	signal
262	Intestinal Obstruction	129	3.9	3.9	signal
263	Decubitus Ulcer	28	3.9	3.9	signal
264	Coagulopathy	57	3.9	3.9	signal
265	Serum Ferritin Increased	18	3.9	3.9	signal
266	Pseudomonas Infection	29	3.9	3.9	signal
267	Neutrophil Count Increased	35	3.9	3.9	signal
268	Abdominal Pain	791	3.9	4.0	signal
269	Oral Disorder	25	3.9	3.9	signal
270	Acidosis	26	3.9	3.9	signal
271	Foot Fracture	64	3.8	3.8	signal
272	Angiopathy	19	3.8	3.8	signal
273	Staphylococcal Infection	110	3.8	3.8	signal
274	Cachexia	17	3.8	3.8	signal
275	Cardiac Valve Disease	19	3.8	3.8	signal
276	Sinus Bradycardia	32	3.8	3.8	signal
277	Bipolar Disorder	36	3.7	3.7	signal
278	Nausea	2,586	3.7	4.2	signal
279	Ear Infection	87	3.7	3.7	signal
280	Haemorrhoids	64	3.7	3.7	signal
281	Colitis Ischaemic	22	3.7	3.7	signal
282	Proctalgia	21	3.7	3.7	signal
283	Rotator Cuff Syndrome	42	3.7	3.7	signal
284	Respiratory Rate Increased	29	3.7	3.7	signal
285	Laceration	31	3.7	3.7	signal
286	Sinusitis	334	3.7	3.7	signal
287	Dystonia	63	3.7	3.7	signal
288	Osteoarthritis	137	3.7	3.7	signal
289	Pleural Effusion	196	3.7	3.7	signal
290	Impaired Quality Of Life	46	3.6	3.6	signal
291	Nephropathy	30	3.6	3.6	signal
292	Lymphoedema	22	3.6	3.6	signal
293	Neutrophil Count Decreased	129	3.6	3.6	signal
294	Fluid Overload	47	3.6	3.6	signal
295	Pancreatitis Acute	71	3.6	3.6	signal
296	Joint Effusion	22	3.6	3.6	signal
297	Rib Fracture	65	3.6	3.6	signal
298	Sickle Cell Anaemia With Crisis	50	3.6	3.6	signal
299	Drug Exposure During Pregnancy	109	3.6	3.6	signal
300	Left Ventricular Dysfunction	21	3.6	3.6	signal
301	Lipase Increased	24	3.6	3.6	signal
302	Pyelonephritis	27	3.6	3.6	signal
303	Pelvic Pain	57	3.6	3.6	signal
304	Right Ventricular Failure	22	3.5	3.5	signal
305	Ankle Fracture	48	3.5	3.5	signal
306	Mouth Ulceration	65	3.5	3.5	signal
307	Incoherent	20	3.5	3.5	signal
308	Obesity	49	3.5	3.5	signal
309	Anxiety	874	3.5	3.6	signal
310	Sepsis	341	3.5	3.5	signal
311	Polyp	20	3.5	3.5	signal
312	Pharyngitis	38	3.5	3.5	signal
313	Pharyngitis Streptococcal	33	3.5	3.5	signal
314	Clostridium Difficile Infection	66	3.5	3.5	signal
315	Night Sweats	98	3.5	3.5	signal
316	Chest Pain	563	3.5	3.5	signal
317	Hypercholesterolaemia	29	3.4	3.5	signal
318	Blood Urea Increased	51	3.4	3.5	signal
319	Ventricular Tachycardia	50	3.4	3.4	signal
320	Brain Fog	44	3.4	3.4	signal
321	Dysuria	111	3.4	3.4	signal
322	Chronic Obstructive Pulmonary Disease	157	3.4	3.4	signal
323	Atrial Flutter	24	3.4	3.4	signal
324	Type 1 Diabetes Mellitus	18	3.4	3.4	signal
325	Tooth Fracture	33	3.4	3.4	signal
326	Arthropod Bite	22	3.4	3.4	signal
327	Thinking Abnormal	56	3.4	3.4	signal
328	Osteoporosis	123	3.4	3.4	signal
329	Body Temperature Increased	61	3.4	3.4	signal
330	Spinal Compression Fracture	25	3.4	3.4	signal
331	Duodenal Ulcer	21	3.4	3.4	signal
332	Obsessive-compulsive Disorder	24	3.4	3.4	signal
333	Hyperglycaemia	108	3.4	3.4	signal
334	Respiratory Distress	82	3.4	3.4	signal
335	Screaming	19	3.4	3.4	signal
336	Skin Laceration	32	3.4	3.4	signal
337	Type 2 Diabetes Mellitus	100	3.4	3.4	signal
338	Tooth Infection	39	3.4	3.4	signal
339	Obstructive Airways Disorder	33	3.4	3.4	signal
340	Hypophagia	75	3.4	3.4	signal
341	Unresponsive To Stimuli	76	3.4	3.4	signal
342	Nephrolithiasis	135	3.4	3.4	signal
343	Renal Failure Acute	127	3.4	3.4	signal
344	Hepatomegaly	29	3.3	3.3	signal
345	Product Distribution Issue	26	3.3	3.3	signal
346	Blood Bilirubin Increased	79	3.3	3.3	signal
347	Respiratory Arrest	81	3.3	3.3	signal
348	Cardiomyopathy	43	3.3	3.3	signal
349	Bursitis	35	3.3	3.3	signal
350	Haemoptysis	81	3.3	3.3	signal
351	Glucose Tolerance Impaired	17	3.3	3.3	signal
352	Pancreatitis	153	3.3	3.3	signal
353	Emotional Distress	351	3.3	3.3	signal
354	Gingival Pain	23	3.3	3.3	signal
355	Haematemesis	73	3.3	3.3	signal
356	Dysgraphia	19	3.3	3.3	signal
357	Feeding Disorder	57	3.3	3.3	signal
358	Ascites	84	3.2	3.3	signal
359	Lymphadenopathy	101	3.2	3.3	signal
360	Generalised Oedema	35	3.2	3.2	signal
361	Sedation	74	3.2	3.2	signal
362	Activities Of Daily Living Impaired	57	3.2	3.2	signal
363	Postoperative Wound Infection	19	3.2	3.2	signal
364	Cystitis	90	3.2	3.2	signal
365	Feeling Drunk	21	3.2	3.2	signal
366	Oral Mucosal Blistering	18	3.2	3.2	signal
367	White Blood Cell Count Increased	108	3.2	3.2	signal
368	Urinary Tract Infection	477	3.2	3.2	signal
369	Bacterial Infection	52	3.2	3.2	signal
370	Cyanosis	44	3.2	3.2	signal
371	Hysterectomy	24	3.2	3.2	signal
372	Back Injury	30	3.2	3.2	signal
373	Panic Attack	101	3.1	3.2	signal
374	Anaemia	527	3.1	3.2	signal
375	Dysphagia	261	3.1	3.2	signal
376	Oedema Peripheral	337	3.1	3.2	signal
377	Fistula	31	3.1	3.1	signal
378	Refusal Of Treatment By Patient	18	3.1	3.1	signal
379	Dyspnoea Exertional	103	3.1	3.1	signal
380	Fear	74	3.1	3.1	signal
381	Hypersomnia	78	3.1	3.1	signal
382	Sensory Loss	22	3.1	3.1	signal
383	Nerve Compression	25	3.1	3.1	signal
384	Post Procedural Complication	52	3.1	3.1	signal
385	Respiratory Tract Infection	70	3.1	3.1	signal
386	Meningitis	18	3.1	3.1	signal
387	Orthostatic Hypotension	47	3.1	3.1	signal
388	Pneumonia Aspiration	67	3.1	3.1	signal
389	Vitamin D Decreased	23	3.1	3.1	signal
390	Dysarthria	101	3.1	3.1	signal
391	Hepatic Encephalopathy	25	3.0	3.0	signal
392	Emotional Disorder	83	3.0	3.1	signal
393	Fungal Infection	89	3.0	3.0	signal
394	Deformity	25	3.0	3.0	signal
395	Eating Disorder	57	3.0	3.0	signal
396	Renal Injury	80	3.0	3.0	signal
397	Drug Screen Positive	21	3.0	3.0	signal
398	Contusion	256	3.0	3.1	signal
399	Depression	608	3.0	3.1	signal
400	Thyroid Disorder	41	3.0	3.0	signal
401	Heart Rate Irregular	60	3.0	3.0	signal
402	Akathisia	36	3.0	3.0	signal
403	Blood Iron Decreased	31	3.0	3.0	signal
404	Chills	308	3.0	3.0	signal
405	Viral Infection	87	3.0	3.0	signal
406	Increased Tendency To Bruise	24	3.0	3.0	signal
407	Anorexia	34	3.0	3.0	signal
408	Toothache	47	3.0	3.0	signal
409	Mental Disorder	113	2.9	3.0	signal
410	Post Procedural Infection	21	2.9	2.9	signal
411	Pneumothorax	41	2.9	2.9	signal
412	Concussion	20	2.9	2.9	signal
413	Urinary Incontinence	76	2.9	2.9	signal
414	Splenomegaly	30	2.9	2.9	signal
415	Neuralgia	62	2.9	2.9	signal
416	Affective Disorder	20	2.9	2.9	signal
417	Acute Kidney Injury	388	2.9	2.9	signal
418	Hand Fracture	18	2.9	2.9	signal
419	Dyskinesia	103	2.9	2.9	signal
420	Muscle Tightness	41	2.9	2.9	signal
421	Colitis	95	2.9	2.9	signal
422	Sciatica	40	2.9	2.9	signal
423	Premature Baby	76	2.9	2.9	signal
424	Pneumonia	813	2.9	2.9	signal
425	Lower Limb Fracture	48	2.9	2.9	signal
426	Nerve Injury	28	2.9	2.9	signal
427	Tachypnoea	34	2.9	2.9	signal
428	Weight Decreased	698	2.8	2.9	signal
429	Diabetes Mellitus	190	2.8	2.8	signal
430	Aortic Aneurysm	19	2.8	2.8	signal
431	Cardiac Failure Congestive	201	2.8	2.8	signal
432	Oedema	134	2.8	2.8	signal
433	Drooling	17	2.8	2.8	signal
434	Low Density Lipoprotein Increased	19	2.8	2.8	signal
435	Dyspepsia	242	2.8	2.8	signal
436	Bacteraemia	29	2.8	2.8	signal
437	Swollen Tongue	77	2.8	2.8	signal
438	Tooth Disorder	55	2.8	2.8	signal
439	Back Pain	571	2.8	2.8	signal
440	Bone Pain	144	2.8	2.8	signal
441	Abdominal Pain Lower	62	2.8	2.8	signal
442	Hernia	47	2.8	2.8	signal
443	Sinus Congestion	33	2.8	2.8	signal
444	Psychiatric Symptom	18	2.8	2.8	signal
445	Urinary Retention	81	2.8	2.8	signal
446	Joint Injury	52	2.8	2.8	signal
447	Intentional Overdose	155	2.8	2.8	signal
448	Mass	34	2.8	2.8	signal
449	Diverticulitis	67	2.8	2.8	signal
450	Spinal Disorder	23	2.8	2.8	signal
451	Poor Venous Access	25	2.8	2.8	signal
452	Carpal Tunnel Syndrome	34	2.8	2.8	signal
453	Developmental Delay	22	2.7	2.8	signal
454	Cyst	30	2.7	2.7	signal
455	Red Blood Cell Count Decreased	69	2.7	2.7	signal
456	Encephalopathy	59	2.7	2.7	signal
457	Chest Discomfort	245	2.7	2.8	signal
458	Constipation	519	2.7	2.8	signal
459	Urine Output Decreased	21	2.7	2.7	signal
460	Decreased Appetite	555	2.7	2.8	signal
461	Pain	1,472	2.7	2.9	signal
462	Illness	240	2.7	2.7	signal
463	Hallucination	179	2.7	2.7	signal
464	Tardive Dyskinesia	68	2.7	2.7	signal
465	Ulcer	38	2.7	2.7	signal
466	Abscess	38	2.7	2.7	signal
467	Premature Delivery	38	2.7	2.7	signal
468	Pharyngeal Oedema	37	2.7	2.7	signal
469	Osteonecrosis Of Jaw	59	2.7	2.7	signal
470	Hyponatraemia	133	2.7	2.7	signal
471	Lethargy	136	2.7	2.7	signal
472	Incontinence	25	2.7	2.7	signal
473	Coronary Artery Disease	72	2.7	2.7	signal
474	Liver Function Test Abnormal	69	2.7	2.7	signal
475	Platelet Count Decreased	251	2.7	2.7	signal
476	Tachycardia	209	2.7	2.7	signal
477	Extrapyramidal Disorder	59	2.7	2.7	signal
478	Convulsion	136	2.7	2.7	signal
479	Rectal Haemorrhage	101	2.7	2.7	signal
480	Impaired Work Ability	50	2.7	2.7	signal
481	Limb Injury	63	2.6	2.6	signal
482	Upper-airway Cough Syndrome	19	2.6	2.6	signal
483	Electrocardiogram Qt Prolonged	83	2.6	2.6	signal
484	Neuropathy Peripheral	218	2.6	2.6	signal
485	Depressed Level Of Consciousness	91	2.6	2.6	signal
486	White Blood Cell Count Decreased	250	2.6	2.6	signal
487	Gastrointestinal Pain	25	2.6	2.6	signal
488	Hypokinesia	33	2.6	2.6	signal
489	Musculoskeletal Discomfort	39	2.6	2.6	signal
490	Ataxia	27	2.6	2.6	signal
491	Respiratory Tract Congestion	36	2.6	2.6	signal
492	Alanine Aminotransferase Increased	139	2.6	2.6	signal
493	Metastases To Bone	37	2.6	2.6	signal
494	Hypothyroidism	72	2.6	2.6	signal
495	Oropharyngeal Pain	209	2.6	2.6	signal
496	Hypoaesthesia	338	2.6	2.6	signal
497	Pulmonary Oedema	101	2.6	2.6	signal
498	Pyrexia	779	2.6	2.6	signal
499	Skin Ulcer	58	2.6	2.6	signal
500	Loss Of Consciousness	288	2.6	2.6	signal
501	Skin Infection	25	2.5	2.5	signal
502	Rhinitis	18	2.5	2.5	signal
503	Abdominal Distension	232	2.5	2.6	signal
504	Wound	62	2.5	2.5	signal
505	Myositis	20	2.5	2.5	signal
506	Paralysis	32	2.5	2.5	signal
507	Blood Pressure Abnormal	44	2.5	2.5	signal
508	Febrile Neutropenia	147	2.5	2.5	signal
509	Body Height Decreased	24	2.5	2.5	signal
510	Amnesia	145	2.5	2.5	signal
511	Vertigo	135	2.5	2.5	signal
512	Infusion Related Reaction	146	2.5	2.5	signal
513	Cold Sweat	39	2.5	2.5	signal
514	Gamma-glutamyltransferase Increased	49	2.5	2.5	signal
515	Oxygen Saturation Decreased	123	2.5	2.5	signal
516	Aspartate Aminotransferase Increased	117	2.5	2.5	signal
517	Hyperhidrosis	284	2.5	2.5	signal
518	Haemoglobin Decreased	226	2.5	2.5	signal
519	Diplopia	57	2.5	2.5	signal
520	Delirium	75	2.5	2.5	signal
521	Rash Maculo-papular	48	2.5	2.5	signal
522	Muscle Twitching	50	2.5	2.5	signal
523	Foot Deformity	24	2.5	2.5	signal
524	Live Birth	18	2.5	2.5	signal
525	Musculoskeletal Pain	114	2.5	2.5	signal
526	Asthenia	811	2.5	2.5	signal
527	Restlessness	79	2.4	2.5	signal
528	Tooth Loss	45	2.4	2.5	signal
529	Productive Cough	102	2.4	2.5	signal
530	Upper Limb Fracture	43	2.4	2.4	signal
531	Sneezing	48	2.4	2.4	signal
532	Blood Pressure Decreased	142	2.4	2.4	signal
533	Crying	78	2.4	2.4	signal
534	Speech Disorder	112	2.4	2.4	signal
535	Palpitations	250	2.4	2.4	signal
536	Injection Site Irritation	27	2.4	2.4	signal
537	Pericardial Effusion	49	2.4	2.4	signal
538	Blister	119	2.4	2.4	signal
539	Abdominal Pain Upper	436	2.4	2.4	signal
540	Myocarditis	24	2.4	2.4	signal
541	Agitation	156	2.4	2.4	signal
542	Hepatic Failure	64	2.4	2.4	signal
543	Micturition Urgency	24	2.4	2.4	signal
544	Wound Infection	23	2.4	2.4	signal
545	Sputum Discoloured	20	2.4	2.4	signal
546	Toxicity To Various Agents	354	2.4	2.4	signal
547	Hypertension	447	2.4	2.4	signal
548	Presyncope	51	2.4	2.4	signal
549	Skin Disorder	70	2.4	2.4	signal
550	Blood Pressure Increased	322	2.4	2.4	signal
551	Haematuria	72	2.4	2.4	signal
552	Psychotic Disorder	62	2.4	2.4	signal
553	Diabetic Ketoacidosis	50	2.4	2.4	signal
554	Upper Gastrointestinal Haemorrhage	35	2.4	2.4	signal
555	Disability	41	2.4	2.4	signal
556	Stress	149	2.4	2.4	signal
557	Hypothermia	21	2.4	2.4	signal
558	Muscle Atrophy	26	2.3	2.4	signal
559	Platelet Count Increased	27	2.3	2.4	signal
560	Fluid Retention	105	2.3	2.4	signal
561	Nocturia	25	2.3	2.3	signal
562	Inappropriate Antidiuretic Hormone Secretion	21	2.3	2.3	signal
563	Wheezing	122	2.3	2.4	signal
564	Pulmonary Arterial Hypertension	30	2.3	2.3	signal
565	Muscle Spasms	378	2.3	2.4	signal
566	Head Injury	65	2.3	2.3	signal
567	Decreased Activity	22	2.3	2.3	signal
568	Eye Infection	23	2.3	2.3	signal
569	Gingival Bleeding	28	2.3	2.3	signal
570	Intestinal Perforation	23	2.3	2.3	signal
571	Purpura	18	2.3	2.3	signal
572	Hepatic Cirrhosis	38	2.3	2.3	signal
573	Hypercalcaemia	25	2.3	2.3	signal
574	Procedural Pain	56	2.3	2.3	signal
575	Hypotension	405	2.3	2.3	signal
576	Insomnia	538	2.3	2.3	signal
577	Sinus Disorder	40	2.3	2.3	signal
578	Diarrhoea	1,297	2.3	2.4	signal
579	Withdrawal Syndrome	85	2.3	2.3	signal
580	Gastric Disorder	70	2.3	2.3	signal
581	Musculoskeletal Stiffness	176	2.3	2.3	signal
582	Suicidal Ideation	184	2.3	2.3	signal
583	Somnolence	402	2.3	2.3	signal
584	Gastric Ulcer	38	2.3	2.3	signal
585	Posterior Reversible Encephalopathy Syndrome	19	2.3	2.3	signal
586	Stomatitis	121	2.3	2.3	signal
587	Tendonitis	31	2.3	2.3	signal
588	Ejection Fraction Decreased	31	2.3	2.3	signal
589	Metabolic Acidosis	63	2.3	2.3	signal
590	Seizure	228	2.3	2.3	signal
591	Tinnitus	91	2.2	2.3	signal
592	Blood Triglycerides Increased	35	2.2	2.2	signal
593	Asthma	221	2.2	2.3	signal
594	Pneumonia Bacterial	18	2.2	2.2	signal
595	Throat Irritation	88	2.2	2.2	signal
596	Cardiac Arrest	163	2.2	2.2	signal
597	Herpes Zoster	113	2.2	2.2	signal
598	Heart Rate Increased	194	2.2	2.2	signal
599	Acute Myocardial Infarction	58	2.2	2.2	signal
600	Aggression	98	2.2	2.2	signal
601	Dyspnoea	1,104	2.2	2.3	signal
602	Hallucination, Auditory	31	2.2	2.2	signal
603	Headache	1,216	2.2	2.3	signal
604	Metastases To Liver	34	2.2	2.2	signal
605	Multi-organ Failure	34	2.2	2.2	signal
606	Quality Of Life Decreased	26	2.2	2.2	signal
607	Thrombosis	156	2.2	2.2	signal
608	Fall	641	2.2	2.2	signal
609	Local Swelling	34	2.2	2.2	signal
610	Tubulointerstitial Nephritis	36	2.2	2.2	signal
611	Septic Shock	83	2.2	2.2	signal
612	Transient Ischaemic Attack	65	2.2	2.2	signal
613	Myocardial Ischaemia	22	2.2	2.2	signal
614	Nodule	25	2.2	2.2	signal
615	Accidental Overdose	70	2.2	2.2	signal
616	Confusional State	310	2.2	2.2	signal
617	International Normalised Ratio Increased	55	2.2	2.2	signal
618	Bladder Disorder	19	2.2	2.2	signal
619	Metastases To Lung	22	2.2	2.2	signal
620	Oral Herpes	37	2.2	2.2	signal
621	Poisoning	24	2.2	2.2	signal
622	Brain Oedema	24	2.2	2.2	signal
623	Tremor	315	2.2	2.2	signal
624	Arthritis	149	2.1	2.2	signal
625	Complication Associated With Device	25	2.1	2.1	signal
626	Jaundice	51	2.1	2.2	signal
627	Road Traffic Accident	79	2.1	2.1	signal
628	Peripheral Coldness	26	2.1	2.1	signal
629	Mania	31	2.1	2.1	signal
630	Ventricular Fibrillation	21	2.1	2.1	signal
631	Glossodynia	42	2.1	2.1	signal
632	Caesarean Section	22	2.1	2.1	signal
633	Pallor	51	2.1	2.1	signal
634	Influenza	209	2.1	2.1	signal
635	Initial Insomnia	19	2.1	2.1	signal
636	Memory Impairment	256	2.1	2.1	signal
637	Fatigue	1,443	2.1	2.2	signal
638	Pain In Extremity	546	2.1	2.1	signal
639	Dysphonia	108	2.1	2.1	signal
640	Device Failure	28	2.1	2.1	signal
641	Gastrointestinal Haemorrhage	155	2.1	2.1	signal
642	Epistaxis	138	2.1	2.1	signal
643	Nightmare	64	2.1	2.1	signal
644	Influenza Like Illness	152	2.1	2.1	signal
645	Gastrointestinal Disorder	162	2.1	2.1	signal
646	Appendicitis	17	2.1	2.1	signal
647	Bedridden	24	2.1	2.1	signal
648	Cardiogenic Shock	26	2.1	2.1	signal
649	Hemiparesis	31	2.1	2.1	signal
650	Infection	262	2.1	2.1	signal
651	Bronchospasm	26	2.1	2.1	signal
652	Grand Mal Convulsion	17	2.1	2.1	signal
653	Mental Impairment	44	2.1	2.1	signal
654	Foetal Exposure During Pregnancy	147	2.1	2.1	signal
655	Syncope	181	2.1	2.1	signal
656	Skin Discolouration	83	2.1	2.1	signal
657	Post Procedural Haemorrhage	21	2.0	2.0	signal
658	Metastases To Central Nervous System	23	2.0	2.0	signal
659	Abasia	45	2.0	2.0	signal
660	Stevens-johnson Syndrome	40	2.0	2.0	signal
661	Mydriasis	23	2.0	2.0	signal
662	Brain Injury	18	2.0	2.0	signal
663	Spinal Pain	21	2.0	2.0	signal
664	Dry Mouth	145	2.0	2.0	signal
665	Disorientation	71	2.0	2.0	signal
666	Arrhythmia	85	2.0	2.0	signal
667	Incorrect Route Of Product Administration	30	2.0	2.0	signal
668	Blood Urine Present	34	2.0	2.0	signal
669	Atrial Fibrillation	174	2.0	2.0	signal
670	Feeling Jittery	34	2.0	2.0	signal
671	Blood Cholesterol Increased	83	2.0	2.0	signal
672	Alopecia	350	2.0	2.0	signal
673	Swelling	166	2.0	2.0	signal
674	Lung Disorder	87	2.0	2.0	signal
675	Sluggishness	18	2.0	2.0	signal
676	Haematoma	46	2.0	2.0	signal
677	Feeling Abnormal	425	2.0	2.0	signal
678	Covid-19 Pneumonia	21	2.0	2.0	signal
679	Blood Creatinine Increased	115	2.0	2.0	no signal
680	Burning Sensation	123	2.0	2.0	no signal
681	Adrenal Insufficiency	21	2.0	2.0	no signal
682	Wrist Fracture	21	2.0	2.0	no signal
683	Immune System Disorder	23	2.0	2.0	no signal
684	Drug Toxicity	24	2.0	2.0	no signal
685	Neoplasm	20	2.0	2.0	no signal
686	Cardio-respiratory Arrest	73	2.0	2.0	no signal
687	Cough	485	2.0	2.0	no signal
688	Angina Pectoris	50	2.0	2.0	no signal
689	Pollakiuria	72	2.0	2.0	no signal
690	Chromaturia	39	2.0	2.0	no signal
691	Back Disorder	28	1.9	1.9	no signal
692	Nervousness	90	1.9	2.0	no signal
693	Rash Generalised	45	1.9	1.9	no signal
694	Suicide Attempt	104	1.9	1.9	no signal
695	Generalised Tonic-clonic Seizure	28	1.9	1.9	no signal
696	Muscular Weakness	193	1.9	1.9	no signal
697	Cognitive Disorder	79	1.9	1.9	no signal
698	Squamous Cell Carcinoma	16	1.9	1.9	no signal
699	No Therapeutic Response	21	1.9	1.9	no signal
700	Blood Count Abnormal	26	1.9	1.9	no signal
701	Malaise	743	1.9	2.0	no signal
702	Arthralgia	699	1.9	2.0	no signal
703	Tooth Extraction	21	1.9	1.9	no signal
704	Wrong Technique In Drug Usage Process	62	1.9	1.9	no signal
705	Poor Quality Sleep	36	1.9	1.9	no signal
706	Coma	80	1.9	1.9	no signal
707	Myoclonus	20	1.9	1.9	no signal
708	Middle Insomnia	31	1.9	1.9	no signal
709	Shock	38	1.9	1.9	no signal
710	Pneumonitis	45	1.9	1.9	no signal
711	Abdominal Discomfort	278	1.9	1.9	no signal
712	Laboratory Test Abnormal	49	1.9	1.9	no signal
713	Hypoaesthesia Oral	25	1.9	1.9	no signal
714	Localised Infection	40	1.9	1.9	no signal
715	Oral Discomfort	23	1.9	1.9	no signal
716	Schizophrenia	20	1.9	1.9	no signal
717	Multiple Sclerosis	79	1.9	1.9	no signal
718	Dependence	91	1.9	1.9	no signal
719	Full Blood Count Decreased	33	1.9	1.9	no signal
720	Rhinorrhoea	105	1.9	1.9	no signal
721	Renal Disorder	76	1.8	1.9	no signal
722	Cytokine Release Syndrome	31	1.8	1.8	no signal
723	Hospice Care	16	1.8	1.8	no signal
724	Psychomotor Hyperactivity	27	1.8	1.8	no signal
725	Myelosuppression	55	1.8	1.8	no signal
726	Transfusion	17	1.8	1.8	no signal
727	Gait Disturbance	310	1.8	1.8	no signal
728	Depressed Mood	85	1.8	1.8	no signal
729	Joint Dislocation	17	1.8	1.8	no signal
730	Impaired Healing	53	1.8	1.8	no signal
731	Systemic Lupus Erythematosus	57	1.8	1.8	no signal
732	Menorrhagia	32	1.8	1.8	no signal
733	Spinal Fracture	32	1.8	1.8	no signal
734	Myalgia	272	1.8	1.8	no signal
735	Hypotonia	16	1.8	1.8	no signal
736	Dermatitis	33	1.8	1.8	no signal
737	Paraesthesia	251	1.8	1.8	no signal
738	Skin Fissures	30	1.8	1.8	no signal
739	Movement Disorder	51	1.8	1.8	no signal
740	Weight Increased	352	1.8	1.8	no signal
741	Thrombocytopenia	176	1.8	1.8	no signal
742	Conjunctivitis	29	1.8	1.8	no signal
743	Hyperkalaemia	55	1.8	1.8	no signal
744	Mucosal Inflammation	41	1.8	1.8	no signal
745	Eyelid Ptosis	16	1.8	1.8	no signal
746	Joint Range Of Motion Decreased	21	1.8	1.8	no signal
747	Swelling Face	102	1.8	1.8	no signal
748	Coordination Abnormal	22	1.8	1.8	no signal
749	Laryngitis	17	1.8	1.8	no signal
750	Hot Flush	118	1.8	1.8	no signal
751	Ear Discomfort	16	1.8	1.8	no signal
752	Joint Stiffness	41	1.8	1.8	no signal
753	Immunodeficiency	23	1.8	1.8	no signal
754	Unevaluable Event	118	1.8	1.8	no signal
755	Sleep Disorder	109	1.8	1.8	no signal
756	Hepatitis C	19	1.8	1.8	no signal
757	Dizziness	773	1.8	1.8	no signal
758	Injection Site Nodule	17	1.8	1.8	no signal
759	Treatment Noncompliance	84	1.8	1.8	no signal
760	Choking	30	1.8	1.8	no signal
761	General Physical Health Deterioration	177	1.7	1.8	no signal
762	Petechiae	16	1.7	1.7	no signal
763	Blood Pressure Fluctuation	37	1.7	1.7	no signal
764	Disturbance In Attention	83	1.7	1.7	no signal
765	Maternal Exposure During Pregnancy	135	1.7	1.7	no signal
766	Coeliac Disease	15	1.7	1.7	no signal
767	Coronary Artery Occlusion	21	1.7	1.7	no signal
768	Photosensitivity Reaction	25	1.7	1.7	no signal
769	Throat Tightness	41	1.7	1.7	no signal
770	Glaucoma	29	1.7	1.7	no signal
771	Flatulence	85	1.7	1.7	no signal
772	Peripheral Swelling	230	1.7	1.7	no signal
773	Prescribed Overdose	29	1.7	1.7	no signal
774	Taste Disorder	30	1.7	1.7	no signal
775	Melaena	33	1.7	1.7	no signal
776	Haematochezia	82	1.7	1.7	no signal
777	Limb Discomfort	46	1.7	1.7	no signal
778	Aphasia	45	1.7	1.7	no signal
779	Abnormal Behaviour	59	1.7	1.7	no signal
780	Mood Swings	47	1.7	1.7	no signal
781	Feeling Cold	41	1.7	1.7	no signal
782	Nasal Congestion	86	1.7	1.7	no signal
783	Skin Lesion	40	1.7	1.7	no signal
784	Bradycardia	78	1.7	1.7	no signal
785	Liver Disorder	65	1.7	1.7	no signal
786	Gastric Haemorrhage	17	1.7	1.7	no signal
787	Balance Disorder	127	1.7	1.7	no signal
788	Pulmonary Thrombosis	16	1.7	1.7	no signal
789	Covid-19	259	1.7	1.7	no signal
790	Hypoglycaemia	71	1.7	1.7	no signal
791	Intentional Dose Omission	40	1.7	1.7	no signal
792	Autoimmune Disorder	14	1.7	1.7	no signal
793	Pruritus Generalised	32	1.7	1.7	no signal
794	Blood Glucose Fluctuation	16	1.7	1.7	no signal
795	Pancytopenia	81	1.7	1.7	no signal
796	Product Administration Error	29	1.7	1.7	no signal
797	Multiple Fractures	24	1.6	1.6	no signal
798	Gout	26	1.6	1.6	no signal
799	Central Nervous System Lesion	20	1.6	1.6	no signal
800	Medication Error	80	1.6	1.6	no signal
801	Altered State Of Consciousness	31	1.6	1.6	no signal
802	Hypersensitivity	266	1.6	1.6	no signal
803	Joint Swelling	172	1.6	1.6	no signal
804	Renal Pain	15	1.6	1.6	no signal
805	Blood Potassium Increased	23	1.6	1.6	no signal
806	Arthropathy	79	1.6	1.6	no signal
807	Exposure During Pregnancy	88	1.6	1.6	no signal
808	Pulmonary Fibrosis	27	1.6	1.6	no signal
809	Urosepsis	13	1.6	1.6	no signal
810	Drug Withdrawal Syndrome	125	1.6	1.6	no signal
811	Blood Thyroid Stimulating Hormone Increased	13	1.6	1.6	no signal
812	Nervous System Disorder	44	1.6	1.6	no signal
813	Hip Fracture	45	1.6	1.6	no signal
814	Salivary Hypersecretion	14	1.6	1.6	no signal
815	Dysstasia	41	1.6	1.6	no signal
816	Paraesthesia Oral	20	1.6	1.6	no signal
817	Flushing	142	1.6	1.6	no signal
818	Pregnancy	28	1.6	1.6	no signal
819	Vision Blurred	189	1.6	1.6	no signal
820	Bone Loss	21	1.6	1.6	no signal
821	Cataract	82	1.6	1.6	no signal
822	Surgery	80	1.6	1.6	no signal
823	Blood Pressure Systolic Increased	27	1.6	1.6	no signal
824	Deafness	36	1.6	1.6	no signal
825	Visual Impairment	169	1.6	1.6	no signal
826	Vasculitis	16	1.6	1.6	no signal
827	Eye Discharge	14	1.6	1.6	no signal
828	Discomfort	83	1.6	1.6	no signal
829	Respiratory Disorder	41	1.6	1.6	no signal
830	Hyperbilirubinaemia	14	1.5	1.5	no signal
831	Pruritus	513	1.5	1.6	no signal
832	Bone Density Decreased	43	1.5	1.5	no signal
833	Rash Pruritic	73	1.5	1.5	no signal
834	Scratch	14	1.5	1.5	no signal
835	Drug Intolerance	130	1.5	1.5	no signal
836	Disease Progression	159	1.5	1.5	no signal
837	Leukopenia	67	1.5	1.5	no signal
838	Dysgeusia	100	1.5	1.5	no signal
839	Faeces Discoloured	29	1.5	1.5	no signal
840	Malignant Neoplasm Progression	136	1.5	1.5	no signal
841	Hallucination, Visual	28	1.5	1.5	no signal
842	Lung Infection	21	1.5	1.5	no signal
843	Anger	45	1.5	1.5	no signal
844	Glomerular Filtration Rate Decreased	16	1.5	1.5	no signal
845	Internal Haemorrhage	15	1.5	1.5	no signal
846	Drug Administered At Inappropriate Site	14	1.5	1.5	no signal
847	Retinal Detachment	12	1.5	1.5	no signal
848	Acute Respiratory Distress Syndrome	23	1.5	1.5	no signal
849	Cerebrovascular Accident	221	1.5	1.5	no signal
850	Lip Swelling	43	1.5	1.5	no signal
851	Product Use Complaint	20	1.5	1.5	no signal
852	Ocular Discomfort	14	1.5	1.5	no signal
853	Multiple Sclerosis Relapse	89	1.5	1.5	no signal
854	Sexual Dysfunction	15	1.5	1.5	no signal
855	Dermatitis Allergic	16	1.5	1.5	no signal
856	Personality Change	12	1.5	1.5	no signal
857	Ageusia	32	1.5	1.5	no signal
858	Increased Appetite	24	1.4	1.5	no signal
859	Heart Rate Decreased	45	1.4	1.4	no signal
860	Drug Withdrawal Syndrome Neonatal	19	1.4	1.4	no signal
861	Red Blood Cell Sedimentation Rate Increased	14	1.4	1.4	no signal
862	Cardiac Disorder	118	1.4	1.4	no signal
863	Neoplasm Progression	44	1.4	1.4	no signal
864	Mood Altered	34	1.4	1.4	no signal
865	Eye Pain	69	1.4	1.4	no signal
866	Drug Abuse	104	1.4	1.4	no signal
867	Renal Impairment	104	1.4	1.4	no signal
868	Interstitial Lung Disease	60	1.4	1.4	no signal
869	Affect Lability	12	1.4	1.4	no signal
870	Face Oedema	21	1.4	1.4	no signal
871	Rash Macular	43	1.4	1.4	no signal
872	Haemorrhage	129	1.4	1.4	no signal
873	Thirst	22	1.4	1.4	no signal
874	Application Site Rash	17	1.4	1.4	no signal
875	Dysmenorrhoea	16	1.4	1.4	no signal
876	Aphonia	17	1.4	1.4	no signal
877	Multiple Organ Dysfunction Syndrome	34	1.4	1.4	no signal
878	Erythema	250	1.4	1.4	no signal
879	Tendon Rupture	15	1.4	1.4	no signal
880	Product Dose Omission Issue	345	1.4	1.4	no signal
881	Rheumatoid Arthritis	137	1.4	1.4	no signal
882	Hepatic Enzyme Increased	82	1.4	1.4	no signal
883	Colon Cancer	18	1.4	1.4	no signal
884	Disseminated Intravascular Coagulation	17	1.4	1.4	no signal
885	Sars-cov-2 Test Positive	16	1.4	1.4	no signal
886	Head Discomfort	21	1.4	1.4	no signal
887	Lower Respiratory Tract Infection	54	1.4	1.4	no signal
888	Eye Swelling	44	1.4	1.4	no signal
889	Eye Disorder	39	1.4	1.4	no signal
890	Bone Marrow Failure	24	1.3	1.3	no signal
891	Muscle Rigidity	14	1.3	1.3	no signal
892	Condition Aggravated	353	1.3	1.3	no signal
893	Leukaemia	11	1.3	1.3	no signal
894	Drug Dose Omission	195	1.3	1.3	no signal
895	Urticaria	193	1.3	1.3	no signal
896	Eructation	22	1.3	1.3	no signal
897	Product Adhesion Issue	41	1.3	1.3	no signal
898	Product Physical Issue	23	1.3	1.3	no signal
899	Rash Erythematous	54	1.3	1.3	no signal
900	Device Occlusion	16	1.3	1.3	no signal
901	Dementia	32	1.3	1.3	no signal
902	Rash	498	1.3	1.3	no signal
903	Drug Interaction	182	1.3	1.3	no signal
904	Feeling Hot	70	1.3	1.3	no signal
905	Intentional Product Use Issue	100	1.3	1.3	no signal
906	Loss Of Personal Independence In Daily Activities	54	1.3	1.3	no signal
907	Blood Lactate Dehydrogenase Increased	18	1.3	1.3	no signal
908	Vaginal Haemorrhage	48	1.3	1.3	no signal
909	Inability To Afford Medication	11	1.3	1.3	no signal
910	Mobility Decreased	80	1.3	1.3	no signal
911	Liver Injury	27	1.3	1.3	no signal
912	Sensory Disturbance	18	1.3	1.3	no signal
913	Neutropenia	150	1.3	1.3	no signal
914	Acute Hepatic Failure	15	1.3	1.3	no signal
915	Apathy	16	1.3	1.3	no signal
916	Delusion	17	1.2	1.2	no signal
917	Blood Creatine Phosphokinase Increased	32	1.2	1.2	no signal
918	Anaphylactic Shock	28	1.2	1.2	no signal
919	Spinal Operation	13	1.2	1.2	no signal
920	Lacrimation Increased	32	1.2	1.2	no signal
921	Palmar-plantar Erythrodysaesthesia Syndrome	25	1.2	1.2	no signal
922	Haemorrhage Intracranial	16	1.2	1.2	no signal
923	Injection Site Discomfort	11	1.2	1.2	no signal
924	Pharmaceutical Product Complaint	28	1.2	1.2	no signal
925	Nasopharyngitis	196	1.2	1.2	no signal
926	Scab	12	1.2	1.2	no signal
927	Cardiac Failure	85	1.2	1.2	no signal
928	Osteonecrosis	35	1.2	1.2	no signal
929	Adverse Reaction	14	1.2	1.2	no signal
930	Knee Arthroplasty	22	1.2	1.2	no signal
931	Dialysis	15	1.2	1.2	no signal
932	Injection Site Rash	32	1.2	1.2	no signal
933	Injection Site Discolouration	13	1.2	1.2	no signal
934	Muscle Spasticity	13	1.2	1.2	no signal
935	Skin Exfoliation	87	1.2	1.2	no signal
936	Subdural Haematoma	15	1.2	1.2	no signal
937	Full Blood Count Abnormal	11	1.2	1.2	no signal
938	Dizziness Postural	10	1.2	1.2	no signal
939	Product Taste Abnormal	14	1.2	1.2	no signal
940	Product Use Issue	194	1.2	1.2	no signal
941	Hyperthyroidism	15	1.2	1.2	no signal
942	Breast Pain	11	1.2	1.2	no signal
943	Liver Function Test Increased	22	1.2	1.2	no signal
944	Knee Operation	10	1.2	1.2	no signal
945	Sudden Death	11	1.2	1.2	no signal
946	Gait Inability	34	1.2	1.2	no signal
947	Vitreous Floaters	10	1.2	1.2	no signal
948	Product Availability Issue	23	1.2	1.2	no signal
949	Inappropriate Schedule Of Drug Administration	74	1.2	1.2	no signal
950	Injection Site Haematoma	15	1.2	1.2	no signal
951	Pericarditis	17	1.2	1.2	no signal
952	Amenorrhoea	17	1.2	1.2	no signal
953	Blood Glucose Decreased	49	1.2	1.2	no signal
954	Inflammatory Bowel Disease	10	1.2	1.2	no signal
955	Inflammation	52	1.1	1.2	no signal
956	Prostatic Specific Antigen Increased	14	1.1	1.1	no signal
957	Therapy Non-responder	45	1.1	1.1	no signal
958	Accident	12	1.1	1.1	no signal
959	Frequent Bowel Movements	27	1.1	1.1	no signal
960	Injection Site Bruising	79	1.1	1.1	no signal
961	Injection Site Pain	304	1.1	1.1	no signal
962	Inappropriate Schedule Of Product Administration	177	1.1	1.1	no signal
963	Therapeutic Response Unexpected	45	1.1	1.1	no signal
964	Irritability	60	1.1	1.1	no signal
965	Intentional Drug Misuse	21	1.1	1.1	no signal
966	Motor Dysfunction	10	1.1	1.1	no signal
967	Helicobacter Infection	10	1.1	1.1	no signal
968	Injection Site Mass	36	1.1	1.1	no signal
969	Drug Prescribing Error	19	1.1	1.1	no signal
970	Completed Suicide	82	1.1	1.1	no signal
971	Ill-defined Disorder	59	1.1	1.1	no signal
972	Dry Eye	47	1.1	1.1	no signal
973	Folliculitis	10	1.1	1.1	no signal
974	Hunger	13	1.1	1.1	no signal
975	Impaired Driving Ability	11	1.1	1.1	no signal
976	Femur Fracture	30	1.1	1.1	no signal
977	Dry Skin	127	1.1	1.1	no signal
978	Erythema Multiforme	9	1.1	1.1	no signal
979	Proteinuria	18	1.1	1.1	no signal
980	Eye Inflammation	9	1.1	1.1	no signal
981	Adverse Drug Reaction	85	1.1	1.1	no signal
982	Myocardial Infarction	167	1.1	1.1	no signal
983	Incorrect Drug Administration Duration	27	1.1	1.1	no signal
984	Overdose	204	1.1	1.1	no signal
985	Hospitalisation	143	1.1	1.1	no signal
986	Rash Papular	21	1.1	1.1	no signal
987	Expired Product Administered	31	1.1	1.1	no signal
988	Breast Cancer Metastatic	10	1.1	1.1	no signal
989	Therapy Partial Responder	14	1.1	1.1	no signal
990	Skin Cancer	20	1.1	1.1	no signal
991	Injection Site Induration	12	1.1	1.1	no signal
992	Drug Effect Less Than Expected	13	1.0	1.0	no signal
993	Device Dislocation	40	1.0	1.0	no signal
994	Plasma Cell Myeloma	36	1.0	1.0	no signal
995	Cytopenia	11	1.0	1.0	no signal
996	Peritonitis	19	1.0	1.0	no signal
997	Embedded Device	9	1.0	1.0	no signal
998	Blood Glucose Increased	172	1.0	1.0	no signal
999	Blindness	37	1.0	1.0	no signal
1000	Body Temperature Decreased	9	1.0	1.0	no signal
1001	Injection Site Pruritus	60	1.0	1.0	no signal
1002	Skin Haemorrhage	13	1.0	1.0	no signal
1003	Basal Cell Carcinoma	14	1.0	1.0	no signal
1004	Hypertensive Crisis	10	1.0	1.0	no signal
1005	Malignant Melanoma	12	1.0	1.0	no signal
1006	Product Dose Omission In Error	24	1.0	1.0	no signal
1007	Secretion Discharge	11	1.0	1.0	no signal
1008	Pain Of Skin	24	1.0	1.0	no signal
1009	Musculoskeletal Disorder	17	1.0	1.0	no signal
1010	Libido Decreased	11	1.0	1.0	no signal
1011	Status Epilepticus	10	1.0	1.0	no signal
1012	Device Issue	77	1.0	1.0	no signal
1013	Subarachnoid Haemorrhage	9	1.0	1.0	no signal
1014	Intentional Product Misuse	76	1.0	1.0	no signal
1015	Euphoric Mood	9	1.0	1.0	no signal
1016	Glycosylated Haemoglobin Increased	22	1.0	1.0	no signal
1017	Brain Neoplasm	8	1.0	1.0	no signal
1018	Visual Acuity Reduced	29	1.0	1.0	no signal
1019	Ovarian Cancer	8	1.0	1.0	no signal
1020	Drug Effect Decreased	47	1.0	1.0	no signal
1021	Eosinophilia	15	1.0	1.0	no signal
1022	Injection Site Swelling	65	1.0	1.0	no signal
1023	Injection Site Haemorrhage	68	1.0	1.0	no signal
1024	Transaminases Increased	19	1.0	1.0	no signal
1025	Blood Test Abnormal	12	1.0	1.0	no signal
1026	Off Label Use	739	1.0	1.0	no signal
1027	Abortion Spontaneous	34	1.0	1.0	no signal
1028	Drug-induced Liver Injury	26	1.0	1.0	no signal
1029	Macular Degeneration	10	1.0	1.0	no signal
1030	Lymphoma	13	1.0	1.0	no signal
1031	Cerebral Haemorrhage	30	1.0	1.0	no signal
1032	Hypoacusis	36	1.0	1.0	no signal
1033	Drug Administration Error	26	0.9	0.9	no signal
1034	Myelodysplastic Syndrome	12	0.9	0.9	no signal
1035	Injection Site Urticaria	20	0.9	0.9	no signal
1036	Hepatitis	21	0.9	0.9	no signal
1037	Decreased Immune Responsiveness	8	0.9	0.9	no signal
1038	Agranulocytosis	15	0.9	0.9	no signal
1039	Needle Issue	23	0.9	0.9	no signal
1040	Application Site Erythema	21	0.9	0.9	no signal
1041	Psoriatic Arthropathy	32	0.9	0.9	no signal
1042	Neoplasm Malignant	53	0.9	0.9	no signal
1043	Toxic Skin Eruption	8	0.9	0.9	no signal
1044	Hip Arthroplasty	12	0.9	0.9	no signal
1045	Injection Site Reaction	54	0.9	0.9	no signal
1046	Hepatic Function Abnormal	29	0.9	0.9	no signal
1047	Device Leakage	33	0.9	0.9	no signal
1048	Cerebral Infarction	19	0.9	0.9	no signal
1049	Injection Site Warmth	16	0.9	0.9	no signal
1050	Product Dose Omission	51	0.9	0.9	no signal
1051	Injection Site Erythema	95	0.9	0.9	no signal
1052	Unintended Pregnancy	8	0.9	0.9	no signal
1053	Drug Dependence	124	0.9	0.9	no signal
1054	Circulatory Collapse	13	0.9	0.9	no signal
1055	Polyneuropathy	9	0.9	0.9	no signal
1056	Product Packaging Issue	7	0.9	0.9	no signal
1057	Drug Ineffective For Unapproved Indication	42	0.9	0.9	no signal
1058	Poisoning Deliberate	7	0.9	0.9	no signal
1059	Prescribed Underdose	15	0.9	0.9	no signal
1060	Angioedema	33	0.8	0.8	no signal
1061	Incorrect Route Of Drug Administration	27	0.8	0.8	no signal
1062	Device Malfunction	50	0.8	0.8	no signal
1063	Fracture	14	0.8	0.8	no signal
1064	Toxic Epidermal Necrolysis	11	0.8	0.8	no signal
1065	Application Site Irritation	9	0.8	0.8	no signal
1066	Cytomegalovirus Infection	12	0.8	0.8	no signal
1067	Abnormal Dreams	20	0.8	0.8	no signal
1068	Colitis Ulcerative	32	0.8	0.8	no signal
1069	Product Quality Issue	96	0.8	0.8	no signal
1070	Lymphopenia	10	0.8	0.8	no signal
1071	Drug Dispensing Error	11	0.8	0.8	no signal
1072	Drug Effect Incomplete	26	0.8	0.8	no signal
1073	Tuberculosis	9	0.8	0.8	no signal
1074	Eye Pruritus	23	0.8	0.8	no signal
1075	Vaginal Discharge	7	0.8	0.8	no signal
1076	Rhabdomyolysis	29	0.8	0.8	no signal
1077	Therapy Interrupted	48	0.8	0.8	no signal
1078	Peritonitis Bacterial	7	0.8	0.8	no signal
1079	Adverse Event	64	0.8	0.8	no signal
1080	Metrorrhagia	12	0.8	0.8	no signal
1081	Therapeutic Response Shortened	22	0.8	0.8	no signal
1082	Ankylosing Spondylitis	9	0.8	0.8	no signal
1083	Lactic Acidosis	22	0.8	0.8	no signal
1084	Drug Eruption	12	0.8	0.8	no signal
1085	Product Substitution Issue	39	0.8	0.8	no signal
1086	Ischaemic Stroke	12	0.8	0.8	no signal
1087	Skeletal Injury	7	0.8	0.8	no signal
1088	Drug Ineffective	880	0.8	0.7	no signal
1089	Drug Level Increased	11	0.8	0.8	no signal
1090	Incorrect Dose Administered	146	0.7	0.7	no signal
1091	Blood Glucose Abnormal	12	0.7	0.7	no signal
1092	Product Packaging Quantity Issue	7	0.7	0.7	no signal
1093	Injection Site Extravasation	8	0.7	0.7	no signal
1094	Diarrhoea Haemorrhagic	6	0.7	0.7	no signal
1095	Blindness Unilateral	9	0.7	0.7	no signal
1096	Product Prescribing Issue	13	0.7	0.7	no signal
1097	Neurotoxicity	11	0.7	0.7	no signal
1098	Hepatocellular Injury	9	0.7	0.7	no signal
1099	Product Use In Unapproved Indication	153	0.7	0.7	no signal
1100	Death	535	0.7	0.7	no signal
1101	Genital Haemorrhage	8	0.7	0.7	no signal
1102	Lung Neoplasm Malignant	25	0.7	0.7	no signal
1103	C-reactive Protein Increased	22	0.7	0.7	no signal
1104	Ocular Hyperaemia	28	0.7	0.7	no signal
1105	Therapeutic Response Decreased	36	0.7	0.7	no signal
1106	Incorrect Product Administration Duration	12	0.7	0.7	no signal
1107	Application Site Pain	13	0.7	0.7	no signal
1108	Device Use Error	20	0.7	0.7	no signal
1109	Drug Level Decreased	6	0.7	0.7	no signal
1110	Skin Reaction	8	0.6	0.6	no signal
1111	Eczema	28	0.6	0.6	no signal
1112	Anosmia	8	0.6	0.6	no signal
1113	Extra Dose Administered	22	0.6	0.6	no signal
1114	Pancreatic Carcinoma	16	0.6	0.6	no signal
1115	Therapy Cessation	28	0.6	0.6	no signal
1116	Drug Reaction With Eosinophilia And Systemic Symptoms	14	0.6	0.6	no signal
1117	Injury Associated With Device	11	0.6	0.6	no signal
1118	Hepatic Cancer	13	0.6	0.6	no signal
1119	Psoriasis	70	0.6	0.6	no signal
1120	Application Site Pruritus	12	0.6	0.6	no signal
1121	Epilepsy	16	0.6	0.6	no signal
1122	Eye Haemorrhage	7	0.6	0.6	no signal
1123	Device Use Issue	9	0.6	0.6	no signal
1124	Therapeutic Product Effect Decreased	23	0.6	0.6	no signal
1125	Acute Myeloid Leukaemia	8	0.6	0.6	no signal
1126	Underdose	37	0.6	0.6	no signal
1127	Eye Irritation	28	0.6	0.6	no signal
1128	Pneumocystis Jirovecii Pneumonia	5	0.6	0.6	no signal
1129	Thyroid Cancer	6	0.6	0.6	no signal
1130	Sleep Disorder Due To A General Medical Condition	8	0.6	0.6	no signal
1131	Poor Quality Product Administered	5	0.6	0.6	no signal
1132	Exposure Via Skin Contact	11	0.6	0.6	no signal
1133	Product Preparation Error	10	0.5	0.5	no signal
1134	Therapeutic Product Effect Incomplete	34	0.5	0.5	no signal
1135	Abnormal Weight Gain	6	0.5	0.5	no signal
1136	Skin Irritation	22	0.5	0.5	no signal
1137	Cardiovascular Disorder	12	0.5	0.5	no signal
1138	Device Adhesion Issue	7	0.5	0.5	no signal
1139	Menstruation Irregular	12	0.5	0.5	no signal
1140	Wrong Technique In Product Usage Process	91	0.5	0.5	no signal
1141	Incorrect Product Storage	6	0.5	0.5	no signal
1142	Skin Burning Sensation	32	0.5	0.5	no signal
1143	Synovitis	8	0.5	0.5	no signal
1144	Product Administered At Inappropriate Site	8	0.5	0.5	no signal
1145	Erectile Dysfunction	11	0.5	0.5	no signal
1146	Product Prescribing Error	10	0.5	0.5	no signal
1147	Dermatitis Atopic	21	0.5	0.5	no signal
1148	Disease Recurrence	20	0.5	0.5	no signal
1149	Therapy Change	4	0.5	0.5	no signal
1150	Renal Cancer	20	0.5	0.5	no signal
1151	Product Dispensing Error	9	0.5	0.5	no signal
1152	Device Difficult To Use	27	0.5	0.5	no signal
1153	Breast Cancer	38	0.5	0.5	no signal
1154	Syringe Issue	7	0.5	0.5	no signal
1155	Acne	30	0.4	0.4	no signal
1156	Hand Deformity	5	0.4	0.4	no signal
1157	Cholestasis	7	0.4	0.4	no signal
1158	Circumstance Or Information Capable Of Leading To Medication Error	12	0.4	0.4	no signal
1159	Device Breakage	14	0.4	0.4	no signal
1160	Incorrect Dose Administered By Device	9	0.4	0.4	no signal
1161	Rebound Effect	4	0.4	0.4	no signal
1162	Breast Cancer Female	9	0.4	0.4	no signal
1163	Treatment Failure	27	0.4	0.4	no signal
1164	Abortion Induced	3	0.4	0.4	no signal
1165	Product Odour Abnormal	3	0.3	0.3	no signal
1166	Accidental Exposure To Product	26	0.3	0.3	no signal
1167	No Adverse Event	46	0.3	0.3	no signal
1168	Gynaecomastia	8	0.3	0.3	no signal
1169	Device Defective	4	0.3	0.3	no signal
1170	Product Complaint	6	0.3	0.3	no signal
1171	Complication Of Device Removal	4	0.3	0.3	no signal
1172	Gastric Cancer	6	0.3	0.3	no signal
1173	Intraocular Pressure Increased	3	0.3	0.3	no signal
1174	Complication Of Device Insertion	3	0.2	0.2	no signal
1175	Device Expulsion	10	0.2	0.2	no signal
1176	Device Delivery System Issue	4	0.2	0.2	no signal
1177	Product Storage Error	13	0.2	0.2	no signal
1178	Drug Dose Omission By Device	9	0.1	0.1	no signal
1179	Wrong Technique In Device Usage Process	5	0.1	0.1	no signal
1180	Bladder Cancer	6	0.1	0.1	no signal
1181	Prostate Cancer	6	0.1	0.1	no signal