Reaction

Infusion Site Discharge reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,688 reports · 178 co-occurring drugs

As of the last recalculation, Infusion Site Discharge appears in 1,688 FAERS reports alongside 178 co-occurring drug terms. The strongest observed disproportionality signal is DIPHENHYDRAMINE HYDROCHLORIDE CAPSULE, LIQUID FILLED (PRR 204.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diphenhydramine Hydrochloride Capsule, Liquid Filled	293	204.4	207.2
Human Immunoglobulin G	282	202.1	204.9
Treprostinil	915	195.1	196.6
Ketoprofen	140	143.4	144.9
Adrenalinum	330	121.6	122.6
Amitriptyline Hydrochloride	133	101.4	102.2
Lidocaine Hydrochloride	354	91.4	91.9
Epinephrine	333	77.9	78.3
Lidocaine	300	76.9	77.3
Lidicaine	217	62.6	62.9
Burn Relief	217	62.6	62.9
Lidocaine Hydrochloride And Epinephrine	217	62.5	62.8
Lidocaine, Menthol	217	61.8	62.0
0Xygen	214	61.2	61.5
Oxygen	214	61.2	61.5
Sodium Chloride Tablet	298	60.4	60.7
Sodium Chloride Tablets	298	60.4	60.7
Lidocaine Hydrochloride And Epinephrine Bitartrate	218	57.7	57.9
Macitentan	271	57.3	57.5
Sodium Chloride	300	56.7	56.9
Lidocaine 4%	217	56.2	56.4
Diphenhydramine	245	55.8	56.0
Sildenafil	217	52.9	53.1
Hydroxyzine Hydrochloride	54	52.3	52.5
Hydroxyzine Hydrochloride Oral	54	52.3	52.5
Cetirizine Hcl	37	50.8	51.0
Sildenafil Powder,	131	49.1	49.3
Tadalafil	318	48.0	48.2
Cyclobenzaprine Hydrochloride	31	43.3	43.5
Fluticasone Propionate Nasal	95	40.9	41.0
Riociguat	101	40.6	40.7
Azelastine	55	39.0	39.1
Clonidine	144	37.8	37.9
Ambrisentan	298	35.5	35.6
Buspirone Hydrochloride	31	35.3	35.4
Diphenhydramine Hydrochloride	366	34.5	34.6
Sildenafil Citrate	295	34.4	34.5
Doxyclycline Hyclate	38	28.1	28.2
Selexipag	51	25.1	25.1
Dicyclomine Hydrochloride	28	24.6	24.7
Tiotropium Bromide Inhalation Spray	22	24.5	24.6
Promethazine Hydrochloride	36	24.4	24.4
Acetaminophen Tablet Extended Release	385	23.8	23.8
Pain Reliever	385	23.8	23.8
Acetaminophen 500Mg	385	23.8	23.8
Tizanidine Hydrochloride	33	22.9	23.0
Fexofenadine Hcl	17	22.9	22.9
Butalbital, Acetaminophen, And Caffeine	18	21.0	21.1
Epoprostenol	22	21.0	21.0
Zinc Gluconate	43	20.8	20.8
Bumetanide	43	20.6	20.6
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	33	20.2	20.2
Naproxen Sodium, Pseudoephedrine Hydrochloride	33	20.1	20.2
Zinc	39	19.9	20.0
Zinc Chloride	39	19.8	19.8
Rosuvastatin Calcium	44	19.7	19.8
Potassium Chloride, Dextrose Monohydrate	126	18.0	18.1
Potassium Chloride Oral	126	18.0	18.1
Potassium Chloride Extended-Release	126	18.0	18.1
Fexofenadine Hydrochloride	31	17.9	17.9
Fluticasone Propionate	170	17.8	17.9
Mupirocin	19	17.6	17.6
Acetaminophen	465	17.3	17.3
Mupirocin Calcium	19	17.2	17.2
Torsemide	45	17.2	17.2
Potassium Chloride	144	16.9	17.0
Levocetirizine Dihydrochloride	32	16.7	16.7
Oxycodone And Acetaminophen Tablets	16	16.7	16.7
Pantoprazole Sodium In 0.9% Sodium Chloride	78	16.2	16.2
Pantoprazole Sodium Injection	78	16.2	16.2
Fluticasone Furoate And Vilanterol Trifenatate	45	15.8	15.8
Biotin	39	15.8	15.8
Guaifenesin	38	15.7	15.7
Oxybutynin Chloride	11	15.6	15.6
Metolazone	14	15.5	15.5
Azithromycin	49	15.4	15.5
Umeclidinium	11	15.2	15.3
Hydroxyzine	57	15.2	15.2
Montelukast Sodium	138	15.1	15.1
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	36	14.9	15.0
Azithromycin Monohydrate	49	14.9	14.9
Famotidine	130	14.7	14.7
Melatonin	62	14.5	14.6
Triamcinolone Acetonide Ointment Usp, 0.05%	27	14.4	14.4
Budesonide, Glycopyrrolate, And Formoterol Fumarate	12	14.3	14.3
Methocarbamol Tablets	19	14.1	14.2
Bosentan	55	13.9	13.9
Meclizine	18	13.7	13.7
Metformin Hydrochloride Tablets	61	13.6	13.6
Metformin Hydrochloride Extended-Release Tablets	61	13.6	13.6
Mometasone Furoate And Formoterol Fumarate Dihydrate	17	13.6	13.6
Metformin Hydrochloride Tablet	61	13.6	13.6
Ipratropium Bromide	38	13.4	13.4
Atorvastatin Calcium, Film Coated	73	13.4	13.4
Amiodarone Hydrochloride	12	13.3	13.3
Clobetasol Propionate Ointment Usp, 0.05%	11	13.2	13.3
Clobetasol Propionate	11	13.2	13.2
Metformin Hydrochloride	61	13.1	13.2
Cefuroxime	12	13.0	13.0
Spironolactone	137	13.0	13.0
Amoxicillin And Clavulanate Potassium	28	12.9	12.9
Cetirizine Hydrochloride Allergy	31	12.8	12.9
Cetirizine Hydrochloride Tablets	31	12.8	12.8
Benzonatate	17	12.8	12.8
Pravastatin Sodium	20	12.6	12.6
Magnesium	80	12.5	12.6
Montelukast	81	12.4	12.5
Ondansetron Hydrochloride	115	12.3	12.4
Loratadine Oral	46	11.8	11.9
Chlorthalidone	11	11.8	11.8
Azithromycin Dihydrate	53	11.5	11.5
Polyethylene Glycol	10	11.5	11.5
Meclizine Hydrochloride	18	11.4	11.5
Cetirizine	69	11.4	11.4
Liothyronine Sodium	8	11.4	11.4
Sucralfate Oral	13	11.4	11.4
Triamcinolone Acetonide	28	11.3	11.4
Sucralfate Oral Suspension	13	11.3	11.3
Cholestyramine	11	11.3	11.3
Vitamin C	80	11.2	11.2
Cyclobenzaprine	44	11.1	11.1
Methocarbamol	20	11.0	11.0
Metoprolol Succinate Er Tablets	54	11.0	11.0
Docusate Sodium 100Mg	21	11.0	11.0
Fluticasone Propionate And Salmeterol Xinafoate	51	10.8	10.8
Cetirizine Hydrochloride	133	10.7	10.7
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	35	10.6	10.6
Sucralfate	20	10.4	10.4
Tobramycin Solution	10	10.3	10.3
Ergocalciferol	274	10.3	10.3
Fluticasone Furoate	10	10.2	10.2
Gabapentin	260	10.2	10.2
Doxycycline Hyclate	54	10.2	10.2
Doxycycline	54	10.0	10.1
Tobramycin Sulfate	10	10.0	10.0
Diphenoxylate Hydrochloride And Atropine Sulfate	11	10.0	10.0
Albuterol Sulfate	212	9.9	9.9
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	39	9.8	9.8
Drs. Clotrimazole	9	9.6	9.7
Family Wellness Clotrimazole	9	9.6	9.7
Clotrimazole Topical	9	9.6	9.6
Prochlorperazine Maleate	7	9.4	9.4
Vilazodone Hydrochloride	7	9.4	9.4
Ferrous Sulfate	36	9.0	9.0
Loratadine	74	8.8	8.8
Metoprolol Succinate	60	8.8	8.8
Oxycodone And Acetaminophen	16	8.5	8.5
Loperamide Hydrochloride	30	8.4	8.4
Losartan Potassium	51	8.2	8.2
Duloxetine	45	8.2	8.2
Thyroid, Porcine	7	8.1	8.1
Acetaminophen And Codeine	8	8.1	8.1
Guanfacine	5	7.9	7.9
Fondaparinux Sodium	5	7.6	7.6
Estradiol Gel 0.1%	27	7.5	7.5
Estradiol Transdermal	27	7.5	7.5
Loratadine Tablet	30	7.0	7.0
Linaclotide	15	7.0	7.0
Rimegepant Sulfate	7	6.8	6.8
Carboxymethylcellulose Sodium	5	6.6	6.6
Rotigotine	7	6.0	6.0
Mirabegron	18	5.8	5.8
Fremanezumab-Vfrm	5	5.4	5.4
Umeclidinium Bromide And Vilanterol Trifenatate	7	5.2	5.2
Tobramycin	10	5.2	5.2
Diclofenac Potassium	4	4.6	4.6
Diclofenac Potassium, Film Coated	3	4.4	4.4
Diclofenac Potassium Tablets	3	4.4	4.4
Acetaminophen, Aspirin (Nsaid) And Caffeine	6	4.4	4.4
Acetaminophen, Aspirin, And Caffeine	7	4.1	4.1
Acalabrutinib	4	4.1	4.1
Cariprazine	3	4.0	4.0
Benralizumab	6	3.7	3.7
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	5	3.4	3.4
Lifitegrast	4	3.0	3.0
Galcanezumab-Gnlm	6	2.4	2.4
Droxidopa	4	2.3	2.3
Nirmatrelvir And Ritonavir	8	1.8	1.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.