Reaction
Anion Gap Increased reporting signals
As of the last recalculation, Anion Gap Increased appears in 1,324 FAERS reports alongside 34 co-occurring drug terms. The strongest observed disproportionality signal is NOREPINEPHRINE (PRR 34.4).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Norepinephrine | 23 | 34.4 | 34.5 |
| Norepinephrine Bitartrate | 29 | 32.4 | 32.4 |
| Acetylcysteine | 15 | 25.3 | 25.3 |
| Calcium, Magnesium, Potassium, And Sodium Oxybates | 13 | 24.0 | 24.0 |
| Derma Foam Excel Hand Sanitizer | 10 | 19.8 | 19.8 |
| Ethanol | 10 | 19.7 | 19.8 |
| Paliperidone | 23 | 15.8 | 15.8 |
| Empagliflozin | 62 | 15.1 | 15.2 |
| Polyethylene Glycol | 10 | 14.6 | 14.6 |
| Metformin Hcl | 49 | 14.4 | 14.4 |
| Nevirapine | 8 | 14.0 | 14.0 |
| Thiamine Hydrochloride | 11 | 14.0 | 14.0 |
| Valproate Sodium | 17 | 13.1 | 13.1 |
| Metformin Er 500 Mg | 212 | 13.0 | 13.0 |
| Metformin Er 750 Mg | 212 | 13.0 | 13.0 |
| Metformin | 243 | 12.9 | 12.9 |
| Canagliflozin | 24 | 12.8 | 12.8 |
| Sodium Bicarbonate | 18 | 12.3 | 12.3 |
| Sodium Bicarbonate Injection, | 18 | 12.3 | 12.3 |
| Dextrose | 10 | 12.0 | 12.0 |
| Dextrose Monohydrate | 10 | 11.8 | 11.9 |
| Methoxy Polyethylene Glycol-Epoetin Beta | 8 | 11.5 | 11.5 |
| Lisinopril And Hydrochlorothiazide Tablets | 5 | 10.0 | 10.0 |
| Tolvaptan | 9 | 9.8 | 9.8 |
| Clozapine | 72 | 9.5 | 9.5 |
| Alcohol | 20 | 8.2 | 8.2 |
| Asfotase Alfa | 5 | 7.9 | 7.9 |
| Amphetamine | 4 | 7.6 | 7.6 |
| Iohexol | 4 | 7.6 | 7.6 |
| Ethyl Alcohol | 10 | 5.8 | 5.8 |
| Somatropin | 25 | 5.4 | 5.4 |
| Paliperidone Palmitate | 10 | 4.9 | 4.9 |
| Blinatumomab | 3 | 4.5 | 4.5 |
| Dornase Alfa | 4 | 3.2 | 3.2 |