Drug

Loratadine Tablet

1,168 flagged reaction(s) · 185,989 total co-reports · max PRR 62.6

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Failure Of Child Resistant Mechanism For Pharmaceutical Product	61	62.6	62.7	signal
2	Accidental Exposure To Product By Child	566	35.5	35.9	signal
3	Chronic Spontaneous Urticaria	76	29.1	29.1	signal
4	Inappropriate Prescribing	34	22.6	22.6	signal
5	Product Package Associated Injury	76	13.9	13.9	signal
6	Extra Dose Administered	1,212	12.3	12.6	signal
7	Patient Dissatisfaction With Treatment	56	11.9	12.0	signal
8	Butterfly Rash	28	11.3	11.3	signal
9	Drug Effect Delayed	121	10.6	10.6	signal
10	Allergy To Animal	27	10.4	10.4	signal
11	Rhinitis Allergic	94	8.5	8.5	signal
12	Nephrogenic Anaemia	94	8.0	8.1	signal
13	Seasonal Allergy	274	7.8	7.8	signal
14	Expired Product Administered	639	7.7	7.8	signal
15	Acute Sinusitis	33	7.7	7.7	signal
16	Pre-existing Condition Improved	111	7.0	7.0	signal
17	Infusion Site Discharge	30	7.0	7.0	signal
18	Nasal Dryness	108	6.9	6.9	signal
19	Cholecystitis Chronic	113	6.6	6.7	signal
20	Essential Hypertension	43	6.6	6.6	signal
21	Sinus Pain	38	6.6	6.6	signal
22	Hyperparathyroidism Secondary	41	6.5	6.5	signal
23	Product Packaging Difficult To Open	40	6.5	6.5	signal
24	Upper-airway Cough Syndrome	132	6.4	6.4	signal
25	Multiple Allergies	125	6.3	6.4	signal
26	Infusion Site Infection	35	6.2	6.2	signal
27	Expired Drug Administered	77	6.1	6.1	signal
28	Incorrect Dosage Administered	75	6.1	6.1	signal
29	Infusion Site Haemorrhage	47	5.8	5.8	signal
30	Ear Congestion	39	5.7	5.7	signal
31	Drug Effect Incomplete	520	5.6	5.7	signal
32	Anxiety Disorder	46	5.4	5.4	signal
33	Sneezing	302	5.4	5.4	signal
34	Otitis Media	44	5.3	5.3	signal
35	Paranasal Sinus Discomfort	50	5.3	5.3	signal
36	Infusion Site Pruritus	41	5.2	5.2	signal
37	Device Infusion Issue	32	5.2	5.2	signal
38	Chronic Sinusitis	48	5.1	5.1	signal
39	Therapeutic Response Unexpected	566	5.0	5.0	signal
40	Drug Administered To Patient Of Inappropriate Age	90	4.9	4.9	signal
41	Monocyte Count Increased	44	4.8	4.8	signal
42	Infusion Site Swelling	73	4.7	4.7	signal
43	Sinus Headache	70	4.6	4.6	signal
44	Sinus Congestion	155	4.5	4.6	signal
45	Lumbar Spinal Stenosis	33	4.5	4.5	signal
46	Spinal Osteoarthritis	99	4.4	4.5	signal
47	Snoring	41	4.3	4.3	signal
48	Infusion Site Erythema	89	4.3	4.3	signal
49	Paranasal Sinus Hypersecretion	41	4.2	4.2	signal
50	Nasal Disorder	28	4.2	4.2	signal
51	Nasal Congestion	609	4.1	4.2	signal
52	Sinus Disorder	206	4.1	4.1	signal
53	Non-cardiac Chest Pain	33	4.1	4.1	signal
54	Migraine With Aura	28	4.1	4.1	signal
55	Sleep Apnoea Syndrome	197	4.1	4.1	signal
56	Infusion Site Pain	130	4.0	4.0	signal
57	Post-traumatic Stress Disorder	68	4.0	4.0	signal
58	Lacrimation Increased	302	4.0	4.0	signal
59	Infective Pulmonary Exacerbation Of Cystic Fibrosis	55	4.0	4.0	signal
60	Nasal Discomfort	79	3.9	3.9	signal
61	Accidental Overdose	362	3.9	3.9	signal
62	Increased Upper Airway Secretion	51	3.9	3.9	signal
63	Arthropod Bite	72	3.9	3.9	signal
64	Thrombophlebitis Superficial	30	3.9	3.9	signal
65	Therapeutic Product Ineffective	38	3.8	3.8	signal
66	Rhinorrhoea	614	3.8	3.8	signal
67	Ear Pruritus	33	3.8	3.8	signal
68	Vitamin B12 Deficiency	38	3.7	3.7	signal
69	Poor Quality Drug Administered	60	3.6	3.6	signal
70	Rebound Acid Hypersecretion	28	3.6	3.6	signal
71	Dermatitis Contact	103	3.6	3.6	signal
72	Hyperlipidaemia	108	3.6	3.6	signal
73	Temperature Intolerance	92	3.6	3.6	signal
74	Sinusitis	924	3.6	3.6	signal
75	Dry Throat	90	3.5	3.5	signal
76	Throat Clearing	32	3.4	3.4	signal
77	Hiatus Hernia	111	3.4	3.4	signal
78	Hair Disorder	71	3.4	3.4	signal
79	Vitamin D Deficiency	83	3.4	3.4	signal
80	Poor Quality Sleep	182	3.4	3.4	signal
81	Ear Discomfort	87	3.4	3.4	signal
82	Throat Irritation	379	3.4	3.4	signal
83	Head Discomfort	149	3.3	3.4	signal
84	Drug Effective For Unapproved Indication	247	3.3	3.4	signal
85	Diabetic Neuropathy	42	3.3	3.3	signal
86	Thyroid Mass	32	3.3	3.3	signal
87	Tricuspid Valve Incompetence	66	3.3	3.3	signal
88	Intervertebral Disc Degeneration	77	3.3	3.3	signal
89	Carotid Artery Stenosis	29	3.3	3.3	signal
90	Hangover	29	3.2	3.2	signal
91	Rhinovirus Infection	31	3.2	3.2	signal
92	Drug Effect Decreased	444	3.2	3.2	signal
93	Periorbital Oedema	42	3.2	3.2	signal
94	Scoliosis	50	3.2	3.2	signal
95	Atelectasis	78	3.2	3.2	signal
96	Ear Pain	154	3.1	3.1	signal
97	Middle Insomnia	145	3.1	3.1	signal
98	Cholecystitis Acute	44	3.1	3.1	signal
99	Bone Lesion	28	3.1	3.1	signal
100	Bronchitis	576	3.1	3.1	signal
101	Gastrooesophageal Reflux Disease	620	3.1	3.1	signal
102	Sputum Discoloured	72	3.0	3.0	signal
103	Diverticulum Intestinal	33	3.0	3.0	signal
104	Rosacea	35	3.0	3.0	signal
105	Somnolence	1,518	3.0	3.0	signal
106	Streptococcal Infection	42	3.0	3.0	signal
107	Blood Pressure Systolic Decreased	34	3.0	3.0	signal
108	Aortic Valve Incompetence	32	3.0	3.0	signal
109	Hair Texture Abnormal	101	3.0	3.0	signal
110	Respiratory Tract Congestion	119	3.0	3.0	signal
111	Nasal Polyps	36	2.9	2.9	signal
112	Mitral Valve Incompetence	84	2.9	2.9	signal
113	Hair Colour Changes	93	2.9	2.9	signal
114	Candidiasis	30	2.9	2.9	signal
115	Urticaria	1,220	2.9	2.9	signal
116	Skin Plaque	61	2.9	2.9	signal
117	Product Prescribing Issue	147	2.9	2.9	signal
118	Diverticulum	52	2.9	2.9	signal
119	Haemorrhagic Anaemia	32	2.8	2.8	signal
120	End Stage Renal Disease	132	2.8	2.8	signal
121	Product Use Issue	1,321	2.8	2.8	signal
122	Aneurysm	35	2.8	2.8	signal
123	Feeling Jittery	133	2.8	2.8	signal
124	Peripheral Vascular Disorder	36	2.7	2.7	signal
125	Eye Swelling	256	2.7	2.7	signal
126	Paraesthesia Oral	99	2.7	2.7	signal
127	Initial Insomnia	70	2.7	2.7	signal
128	Onychoclasis	47	2.7	2.7	signal
129	Photosensitivity Reaction	111	2.7	2.7	signal
130	Frustration Tolerance Decreased	54	2.7	2.7	signal
131	Gallbladder Disorder	120	2.6	2.6	signal
132	Asthma	751	2.6	2.7	signal
133	Pharyngeal Swelling	64	2.6	2.6	signal
134	Spinal Column Stenosis	32	2.6	2.6	signal
135	Haemoglobin Increased	30	2.6	2.6	signal
136	Vascular Device Infection	30	2.6	2.6	signal
137	Eye Pruritus	217	2.6	2.6	signal
138	Demyelination	27	2.6	2.6	signal
139	Product Taste Abnormal	88	2.6	2.6	signal
140	Renal Cyst	52	2.6	2.6	signal
141	Product Administration Interrupted	50	2.6	2.6	signal
142	Tension Headache	28	2.6	2.6	signal
143	Ear Infection	172	2.6	2.6	signal
144	Upper Respiratory Tract Infection	298	2.5	2.6	signal
145	Weight Fluctuation	67	2.5	2.5	signal
146	Breast Mass	43	2.5	2.5	signal
147	Ligament Sprain	63	2.5	2.5	signal
148	Skin Warm	37	2.5	2.5	signal
149	Exostosis	58	2.5	2.5	signal
150	Food Allergy	48	2.5	2.5	signal
151	Rhinitis	51	2.5	2.5	signal
152	Impaired Quality Of Life	91	2.5	2.5	signal
153	Tenderness	66	2.5	2.5	signal
154	Drug Ineffective For Unapproved Indication	351	2.5	2.5	signal
155	Cardiomegaly	78	2.5	2.5	signal
156	Facial Pain	56	2.5	2.5	signal
157	Carpal Tunnel Syndrome	88	2.5	2.5	signal
158	Oral Pain	140	2.5	2.5	signal
159	Obsessive-compulsive Disorder	50	2.4	2.4	signal
160	Increased Tendency To Bruise	57	2.4	2.4	signal
161	Throat Tightness	167	2.4	2.4	signal
162	Pain In Jaw	175	2.4	2.4	signal
163	Drug Ineffective	8,106	2.4	2.7	signal
164	Concomitant Disease Aggravated	38	2.4	2.4	signal
165	Restless Legs Syndrome	112	2.4	2.4	signal
166	Blood Magnesium Decreased	53	2.4	2.4	signal
167	Bone Pain	359	2.4	2.4	signal
168	Psychomotor Hyperactivity	102	2.4	2.4	signal
169	Musculoskeletal Discomfort	105	2.4	2.4	signal
170	Scratch	63	2.4	2.4	signal
171	Madarosis	71	2.4	2.4	signal
172	Energy Increased	36	2.4	2.4	signal
173	Thirst	108	2.4	2.4	signal
174	Product Packaging Issue	56	2.4	2.4	signal
175	Nocturia	73	2.4	2.4	signal
176	Chronic Kidney Disease	461	2.4	2.4	signal
177	Meniscus Injury	37	2.4	2.4	signal
178	Lip Swelling	199	2.4	2.4	signal
179	Vitamin D Decreased	51	2.3	2.3	signal
180	Odynophagia	35	2.3	2.3	signal
181	Cheilitis	32	2.3	2.3	signal
182	Abdominal Hernia	27	2.3	2.3	signal
183	Thermal Burn	42	2.3	2.3	signal
184	Spinal Disorder	56	2.3	2.3	signal
185	Renal Failure Chronic	46	2.3	2.3	signal
186	Laryngitis	64	2.3	2.3	signal
187	Breath Sounds Abnormal	29	2.3	2.3	signal
188	Endometriosis	28	2.3	2.3	signal
189	Cardiac Murmur	51	2.3	2.3	signal
190	Phlebitis	30	2.3	2.3	signal
191	Bursitis	70	2.3	2.3	signal
192	Red Blood Cell Count Decreased	166	2.3	2.3	signal
193	Muscle Strain	50	2.3	2.3	signal
194	Irritable Bowel Syndrome	123	2.3	2.3	signal
195	Pharyngolaryngeal Pain	31	2.3	2.3	signal
196	Supraventricular Tachycardia	55	2.3	2.3	signal
197	Arteriosclerosis Coronary Artery	38	2.3	2.3	signal
198	Toothache	104	2.3	2.3	signal
199	Major Depression	42	2.3	2.3	signal
200	Nervousness	301	2.3	2.3	signal
201	Sensitivity To Weather Change	30	2.3	2.3	signal
202	Muscle Tightness	92	2.2	2.2	signal
203	Blood Potassium Decreased	171	2.2	2.2	signal
204	Eye Discharge	58	2.2	2.2	signal
205	Iron Deficiency Anaemia	52	2.2	2.2	signal
206	Therapeutic Response Shortened	180	2.2	2.2	signal
207	Body Height Decreased	61	2.2	2.2	signal
208	Hypersensitivity	1,044	2.2	2.2	signal
209	Productive Cough	266	2.2	2.2	signal
210	Oropharyngeal Pain	520	2.2	2.2	signal
211	Somnambulism	37	2.2	2.2	signal
212	Swelling Face	365	2.2	2.2	signal
213	Oropharyngeal Discomfort	50	2.2	2.2	signal
214	Rotator Cuff Syndrome	72	2.2	2.2	signal
215	Secretion Discharge	69	2.2	2.2	signal
216	Osteopenia	85	2.2	2.2	signal
217	Cardiac Flutter	36	2.2	2.2	signal
218	Dry Mouth	450	2.2	2.2	signal
219	Blood Uric Acid Increased	32	2.2	2.2	signal
220	Scar	95	2.2	2.2	signal
221	Faecal Incontinence	27	2.2	2.2	signal
222	Swollen Tongue	172	2.2	2.2	signal
223	Sensation Of Foreign Body	46	2.2	2.2	signal
224	Product Use Complaint	85	2.2	2.2	signal
225	Wheezing	324	2.2	2.2	signal
226	Epistaxis	410	2.2	2.2	signal
227	Dry Eye	265	2.2	2.2	signal
228	Screaming	35	2.2	2.2	signal
229	Exercise Tolerance Decreased	31	2.1	2.1	signal
230	Intervertebral Disc Protrusion	119	2.1	2.1	signal
231	Cholelithiasis	178	2.1	2.1	signal
232	Concussion	42	2.1	2.1	signal
233	Urine Odour Abnormal	32	2.1	2.1	signal
234	Hyperkeratosis	30	2.1	2.1	signal
235	Gastroenteritis Viral	98	2.1	2.1	signal
236	Cough	1,512	2.1	2.2	signal
237	Cholecystitis	64	2.1	2.1	signal
238	Micturition Urgency	61	2.1	2.1	signal
239	Pharyngitis	67	2.1	2.1	signal
240	Heart Rate Increased	527	2.1	2.1	signal
241	Nerve Compression	49	2.1	2.1	signal
242	Insurance Issue	79	2.1	2.1	signal
243	Tooth Infection	70	2.1	2.1	signal
244	Haemorrhoids	103	2.1	2.1	signal
245	Neutrophil Count Increased	54	2.1	2.1	signal
246	Anosmia	76	2.1	2.1	signal
247	Dyspnoea Exertional	196	2.1	2.1	signal
248	Palpitations	610	2.1	2.1	signal
249	Pharyngeal Oedema	81	2.0	2.0	signal
250	Postoperative Wound Infection	35	2.0	2.0	signal
251	White Blood Cell Count Abnormal	33	2.0	2.0	signal
252	Gastritis	136	2.0	2.0	signal
253	Pharyngitis Streptococcal	56	2.0	2.0	signal
254	Ovarian Cyst	52	2.0	2.0	signal
255	Blood Pressure Increased	791	2.0	2.1	signal
256	Crying	188	2.0	2.0	signal
257	Chest Discomfort	525	2.0	2.0	signal
258	Extrasystoles	36	2.0	2.0	signal
259	Anaphylactic Reaction	282	2.0	2.0	signal
260	Haematocrit Decreased	102	2.0	2.0	signal
261	Insomnia	1,360	2.0	2.0	signal
262	Photophobia	95	2.0	2.0	signal
263	Osteoarthritis	216	2.0	2.0	signal
264	Tinnitus	234	2.0	2.0	signal
265	Oral Candidiasis	66	2.0	2.0	no signal
266	Fibromyalgia	123	2.0	2.0	no signal
267	Blood Urea Increased	85	2.0	2.0	no signal
268	Pulmonary Mass	75	2.0	2.0	no signal
269	Decubitus Ulcer	41	2.0	2.0	no signal
270	Bipolar Disorder	55	2.0	2.0	no signal
271	Multiple Injuries	32	2.0	2.0	no signal
272	Blood Urine Present	95	2.0	2.0	no signal
273	Visual Disturbance	29	2.0	2.0	no signal
274	Product Use In Unapproved Indication	1,213	2.0	2.0	no signal
275	Hypersomnia	142	2.0	2.0	no signal
276	Red Blood Cell Sedimentation Rate Increased	55	2.0	2.0	no signal
277	Blood Pressure Systolic Increased	97	2.0	2.0	no signal
278	Symptom Recurrence	29	1.9	1.9	no signal
279	Lung Infiltration	44	1.9	1.9	no signal
280	Low Density Lipoprotein Increased	38	1.9	1.9	no signal
281	Pneumonia Aspiration	123	1.9	1.9	no signal
282	Glucose Tolerance Impaired	29	1.9	1.9	no signal
283	Brain Fog	72	1.9	1.9	no signal
284	Vitreous Floaters	48	1.9	1.9	no signal
285	Lymphoedema	34	1.9	1.9	no signal
286	Coronary Artery Disease	150	1.9	1.9	no signal
287	Hypercholesterolaemia	47	1.9	1.9	no signal
288	Decreased Interest	29	1.9	1.9	no signal
289	Neuralgia	119	1.9	1.9	no signal
290	Ventricular Extrasystoles	51	1.9	1.9	no signal
291	Deep Vein Thrombosis	320	1.9	1.9	no signal
292	Neck Pain	274	1.9	1.9	no signal
293	Rash Pruritic	264	1.9	1.9	no signal
294	Dental Caries	54	1.9	1.9	no signal
295	Mouth Swelling	28	1.9	1.9	no signal
296	Pleurisy	29	1.9	1.9	no signal
297	Rash Papular	109	1.9	1.9	no signal
298	Lower Gastrointestinal Haemorrhage	36	1.9	1.9	no signal
299	Ulcer	77	1.9	1.9	no signal
300	Laceration	46	1.9	1.9	no signal
301	Social Avoidant Behaviour	28	1.9	1.9	no signal
302	Tongue Disorder	35	1.9	1.9	no signal
303	Viral Infection	159	1.9	1.9	no signal
304	Flushing	488	1.9	1.9	no signal
305	Uterine Leiomyoma	35	1.9	1.9	no signal
306	Migraine	452	1.9	1.9	no signal
307	Feeling Abnormal	1,145	1.9	1.9	no signal
308	Dysphonia	278	1.9	1.9	no signal
309	Dysgeusia	355	1.9	1.9	no signal
310	Inguinal Hernia	29	1.9	1.9	no signal
311	Blood Alkaline Phosphatase Increased	118	1.9	1.9	no signal
312	Emphysema	48	1.9	1.9	no signal
313	Economic Problem	73	1.9	1.9	no signal
314	Bladder Disorder	47	1.9	1.9	no signal
315	Ankle Fracture	73	1.9	1.9	no signal
316	Diverticulitis	130	1.9	1.9	no signal
317	Blood Albumin Decreased	37	1.8	1.8	no signal
318	Cyst	58	1.8	1.8	no signal
319	Blood Iron Decreased	55	1.8	1.8	no signal
320	Therapeutic Response Changed	29	1.8	1.8	no signal
321	Feeling Hot	286	1.8	1.8	no signal
322	Musculoskeletal Chest Pain	72	1.8	1.8	no signal
323	Spinal Compression Fracture	39	1.8	1.8	no signal
324	Blood Cholesterol Increased	216	1.8	1.8	no signal
325	Pulmonary Congestion	61	1.8	1.8	no signal
326	Dyspepsia	452	1.8	1.8	no signal
327	Pruritus Generalised	101	1.8	1.8	no signal
328	Anxiety	1,312	1.8	1.8	no signal
329	Oral Discomfort	64	1.8	1.8	no signal
330	Formication	32	1.8	1.8	no signal
331	Pruritus	1,732	1.8	1.8	no signal
332	Hypoaesthesia Oral	69	1.8	1.8	no signal
333	Ocular Hyperaemia	214	1.8	1.8	no signal
334	Cholecystectomy	52	1.8	1.8	no signal
335	Stress	329	1.8	1.8	no signal
336	Unevaluable Event	346	1.8	1.8	no signal
337	Skin Infection	51	1.8	1.8	no signal
338	Tendonitis	71	1.8	1.8	no signal
339	Feeling Drunk	34	1.8	1.8	no signal
340	Impaired Gastric Emptying	58	1.8	1.8	no signal
341	Eye Infection	51	1.8	1.8	no signal
342	Pulmonary Hypertension	95	1.8	1.8	no signal
343	Quality Of Life Decreased	61	1.8	1.8	no signal
344	Cellulitis	229	1.8	1.8	no signal
345	No Therapeutic Response	56	1.8	1.8	no signal
346	Menstrual Disorder	37	1.8	1.8	no signal
347	Neuropathy Peripheral	427	1.8	1.8	no signal
348	Conjunctivitis	83	1.8	1.8	no signal
349	Aphonia	63	1.8	1.8	no signal
350	Full Blood Count Decreased	91	1.8	1.8	no signal
351	Obesity	72	1.8	1.8	no signal
352	Angioedema	199	1.8	1.8	no signal
353	Respiratory Tract Infection	117	1.8	1.8	no signal
354	Tooth Abscess	46	1.8	1.8	no signal
355	Infusion Site Extravasation	28	1.8	1.8	no signal
356	Type 2 Diabetes Mellitus	152	1.8	1.8	no signal
357	Malnutrition	50	1.8	1.8	no signal
358	White Blood Cell Count Increased	173	1.8	1.8	no signal
359	Acute Respiratory Failure	86	1.8	1.8	no signal
360	Coordination Abnormal	63	1.8	1.8	no signal
361	Progressive Multifocal Leukoencephalopathy	37	1.8	1.8	no signal
362	Headache	2,804	1.8	1.8	no signal
363	Cystitis	143	1.8	1.8	no signal
364	Chest Pain	829	1.8	1.8	no signal
365	Pollakiuria	186	1.8	1.8	no signal
366	Local Swelling	79	1.8	1.8	no signal
367	Hypothyroidism	142	1.8	1.8	no signal
368	Appetite Disorder	29	1.8	1.8	no signal
369	Depression	1,012	1.7	1.8	no signal
370	Mass	62	1.7	1.7	no signal
371	Eczema	222	1.7	1.7	no signal
372	Hot Flush	332	1.7	1.7	no signal
373	Lymphadenopathy	156	1.7	1.7	no signal
374	Haemoptysis	123	1.7	1.7	no signal
375	Dysuria	162	1.7	1.7	no signal
376	Respiration Abnormal	30	1.7	1.7	no signal
377	Decreased Activity	47	1.7	1.7	no signal
378	Back Pain	1,014	1.7	1.7	no signal
379	Urinary Tract Infection	741	1.7	1.7	no signal
380	Arthritis	343	1.7	1.7	no signal
381	Circumstance Or Information Capable Of Leading To Medication Error	146	1.7	1.7	no signal
382	Skin Laceration	47	1.7	1.7	no signal
383	Gout	78	1.7	1.7	no signal
384	Feeling Cold	121	1.7	1.7	no signal
385	Wrist Fracture	52	1.7	1.7	no signal
386	Abdominal Discomfort	723	1.7	1.7	no signal
387	Retching	92	1.7	1.7	no signal
388	Product Label Issue	29	1.7	1.7	no signal
389	Papule	30	1.7	1.7	no signal
390	Chronic Obstructive Pulmonary Disease	225	1.7	1.7	no signal
391	Candida Infection	72	1.7	1.7	no signal
392	Heart Rate Irregular	98	1.7	1.7	no signal
393	Flatulence	244	1.7	1.7	no signal
394	Rash Macular	150	1.7	1.7	no signal
395	Panic Attack	157	1.7	1.7	no signal
396	Muscle Disorder	35	1.7	1.7	no signal
397	Infusion Related Reaction	284	1.7	1.7	no signal
398	Upper Limb Fracture	86	1.7	1.7	no signal
399	Sunburn	32	1.7	1.7	no signal
400	Dizziness	2,135	1.7	1.7	no signal
401	Tendon Disorder	28	1.7	1.7	no signal
402	Nasopharyngitis	790	1.7	1.7	no signal
403	Splenomegaly	50	1.7	1.7	no signal
404	Injury	301	1.7	1.7	no signal
405	Cardiomyopathy	63	1.7	1.7	no signal
406	Body Temperature Decreased	42	1.7	1.7	no signal
407	Fatigue	3,265	1.7	1.7	no signal
408	Clostridium Difficile Infection	91	1.7	1.7	no signal
409	Bowel Movement Irregularity	32	1.7	1.7	no signal
410	Joint Effusion	29	1.7	1.7	no signal
411	Transient Ischaemic Attack	142	1.7	1.7	no signal
412	Discomfort	254	1.7	1.7	no signal
413	Drug Screen Positive	33	1.6	1.6	no signal
414	Activities Of Daily Living Impaired	84	1.6	1.6	no signal
415	Blood Pressure Diastolic Decreased	31	1.6	1.6	no signal
416	Limb Injury	113	1.6	1.6	no signal
417	Hysterectomy	36	1.6	1.6	no signal
418	Constipation	901	1.6	1.7	no signal
419	Injection Site Urticaria	101	1.6	1.6	no signal
420	Chromaturia	94	1.6	1.6	no signal
421	Tooth Disorder	93	1.6	1.6	no signal
422	Visual Field Defect	30	1.6	1.6	no signal
423	Anal Incontinence	37	1.6	1.6	no signal
424	Respiratory Rate Increased	37	1.6	1.6	no signal
425	Foot Fracture	79	1.6	1.6	no signal
426	Anger	141	1.6	1.6	no signal
427	Scab	47	1.6	1.6	no signal
428	Ocular Discomfort	45	1.6	1.6	no signal
429	Gingival Pain	33	1.6	1.6	no signal
430	Sleep Disorder Due To A General Medical Condition	67	1.6	1.6	no signal
431	Hepatic Steatosis	77	1.6	1.6	no signal
432	Blood Test Abnormal	58	1.6	1.6	no signal
433	Contusion	397	1.6	1.6	no signal
434	Mood Altered	112	1.6	1.6	no signal
435	Blood Triglycerides Increased	73	1.6	1.6	no signal
436	Gastroenteritis	60	1.6	1.6	no signal
437	Muscle Spasms	754	1.6	1.6	no signal
438	Vertigo	250	1.6	1.6	no signal
439	Drug Hypersensitivity	796	1.6	1.6	no signal
440	Abdominal Pain Upper	841	1.6	1.6	no signal
441	Paraesthesia	642	1.6	1.6	no signal
442	Adverse Reaction	54	1.6	1.6	no signal
443	Post Procedural Infection	33	1.6	1.6	no signal
444	Chills	477	1.6	1.6	no signal
445	Platelet Count Increased	53	1.6	1.6	no signal
446	Disturbance In Attention	219	1.6	1.6	no signal
447	Atrial Septal Defect	34	1.6	1.6	no signal
448	Anhedonia	107	1.6	1.6	no signal
449	Eye Pain	223	1.6	1.6	no signal
450	Dysphagia	382	1.6	1.6	no signal
451	Osteomyelitis	73	1.6	1.6	no signal
452	Dyspnoea	2,280	1.6	1.6	no signal
453	Cataract	239	1.6	1.6	no signal
454	Immune System Disorder	53	1.6	1.6	no signal
455	Crohn's Disease	28	1.6	1.6	no signal
456	Urinary Incontinence	119	1.6	1.6	no signal
457	Choking	78	1.6	1.6	no signal
458	Hunger	54	1.6	1.6	no signal
459	Body Temperature Increased	82	1.6	1.6	no signal
460	Inappropriate Schedule Of Drug Administration	289	1.6	1.6	no signal
461	Glaucoma	77	1.6	1.6	no signal
462	Rash	1,731	1.6	1.6	no signal
463	Emotional Disorder	123	1.6	1.6	no signal
464	Pelvic Pain	72	1.6	1.6	no signal
465	Lymphocyte Count Decreased	70	1.6	1.6	no signal
466	Oedema Peripheral	484	1.6	1.6	no signal
467	Oral Disorder	29	1.6	1.6	no signal
468	Rib Fracture	81	1.6	1.6	no signal
469	Musculoskeletal Pain	208	1.6	1.6	no signal
470	Back Disorder	64	1.5	1.5	no signal
471	Peripheral Coldness	54	1.5	1.5	no signal
472	Influenza	438	1.5	1.5	no signal
473	Night Sweats	126	1.5	1.5	no signal
474	Nail Disorder	34	1.5	1.5	no signal
475	Nodule	51	1.5	1.5	no signal
476	Oxygen Saturation Decreased	218	1.5	1.5	no signal
477	Blood Count Abnormal	60	1.5	1.5	no signal
478	Lethargy	223	1.5	1.5	no signal
479	Limb Discomfort	120	1.5	1.5	no signal
480	Skin Fissures	73	1.5	1.5	no signal
481	Autoimmune Disorder	37	1.5	1.5	no signal
482	Erythema	793	1.5	1.5	no signal
483	Sleep Disorder	270	1.5	1.5	no signal
484	Pain In Extremity	1,137	1.5	1.5	no signal
485	Flank Pain	36	1.5	1.5	no signal
486	Coronary Artery Occlusion	53	1.5	1.5	no signal
487	Ageusia	96	1.5	1.5	no signal
488	Drug Effect Less Than Expected	54	1.5	1.5	no signal
489	Fungal Infection	127	1.5	1.5	no signal
490	Electrocardiogram Abnormal	30	1.5	1.5	no signal
491	Nausea	2,994	1.5	1.5	no signal
492	Back Injury	41	1.5	1.5	no signal
493	Sciatica	60	1.5	1.5	no signal
494	Impaired Healing	124	1.5	1.5	no signal
495	Blood Sodium Decreased	71	1.5	1.5	no signal
496	Urine Output Decreased	33	1.5	1.5	no signal
497	Burning Sensation	264	1.5	1.5	no signal
498	Skin Discolouration	173	1.5	1.5	no signal
499	Dermatitis	78	1.5	1.5	no signal
500	Hypoaesthesia	564	1.5	1.5	no signal
501	Peripheral Swelling	577	1.5	1.5	no signal
502	Hospice Care	37	1.5	1.5	no signal
503	Breast Pain	40	1.5	1.5	no signal
504	Eye Irritation	209	1.5	1.5	no signal
505	Dizziness Postural	36	1.5	1.5	no signal
506	Hyperaesthesia	31	1.5	1.5	no signal
507	Eosinophil Count Increased	31	1.5	1.5	no signal
508	Myalgia	633	1.5	1.5	no signal
509	Atrial Fibrillation	363	1.5	1.5	no signal
510	Tooth Fracture	41	1.5	1.5	no signal
511	Parosmia	28	1.5	1.5	no signal
512	Hereditary Angioedema	39	1.5	1.5	no signal
513	Glossodynia	83	1.5	1.5	no signal
514	Pulmonary Embolism	354	1.5	1.5	no signal
515	Head Injury	117	1.5	1.5	no signal
516	Dehydration	494	1.5	1.5	no signal
517	Mood Swings	118	1.5	1.5	no signal
518	Weight Decreased	1,032	1.5	1.5	no signal
519	Affective Disorder	29	1.5	1.5	no signal
520	Renal Injury	111	1.5	1.5	no signal
521	Renal Pain	39	1.5	1.5	no signal
522	Hypertension	782	1.5	1.5	no signal
523	Vision Blurred	502	1.4	1.5	no signal
524	Eye Haemorrhage	49	1.4	1.4	no signal
525	Oesophagitis	40	1.4	1.4	no signal
526	Pericardial Effusion	84	1.4	1.4	no signal
527	Eating Disorder	78	1.4	1.4	no signal
528	Diarrhoea	2,343	1.4	1.5	no signal
529	Overdose	789	1.4	1.4	no signal
530	Presyncope	88	1.4	1.4	no signal
531	Abnormal Behaviour	145	1.4	1.4	no signal
532	Blood Calcium Decreased	41	1.4	1.4	no signal
533	Thyroid Disorder	56	1.4	1.4	no signal
534	Device Related Infection	56	1.4	1.4	no signal
535	Atrial Flutter	29	1.4	1.4	no signal
536	Illness	363	1.4	1.4	no signal
537	Nephrolithiasis	165	1.4	1.4	no signal
538	Hypoxia	126	1.4	1.4	no signal
539	Pneumonia	1,161	1.4	1.4	no signal
540	Nerve Injury	40	1.4	1.4	no signal
541	Dermatitis Atopic	179	1.4	1.4	no signal
542	Therapeutic Response Decreased	216	1.4	1.4	no signal
543	Balance Disorder	310	1.4	1.4	no signal
544	Paranoia	62	1.4	1.4	no signal
545	Herpes Zoster	206	1.4	1.4	no signal
546	Weight Increased	797	1.4	1.4	no signal
547	Incorrect Dose Administered	804	1.4	1.4	no signal
548	Irritability	215	1.4	1.4	no signal
549	Kidney Infection	70	1.4	1.4	no signal
550	Swelling	333	1.4	1.4	no signal
551	Staphylococcal Infection	118	1.4	1.4	no signal
552	Increased Appetite	67	1.4	1.4	no signal
553	Product Physical Issue	71	1.4	1.4	no signal
554	Mental Status Changes	99	1.4	1.4	no signal
555	Abnormal Dreams	99	1.4	1.4	no signal
556	Inflammatory Bowel Disease	35	1.4	1.4	no signal
557	Lung Infection	56	1.4	1.4	no signal
558	Cardiac Failure Congestive	286	1.4	1.4	no signal
559	Fluid Retention	179	1.4	1.4	no signal
560	Abdominal Distension	366	1.4	1.4	no signal
561	Influenza Like Illness	290	1.4	1.4	no signal
562	Eye Disorder	115	1.4	1.4	no signal
563	Bacterial Infection	65	1.4	1.4	no signal
564	Hyperhidrosis	451	1.4	1.4	no signal
565	Osteoporosis	144	1.4	1.4	no signal
566	Device Failure	53	1.4	1.4	no signal
567	Taste Disorder	70	1.4	1.4	no signal
568	White Blood Cell Count Decreased	379	1.4	1.4	no signal
569	Pleural Effusion	212	1.4	1.4	no signal
570	Dry Skin	457	1.4	1.4	no signal
571	Product Odour Abnormal	36	1.4	1.4	no signal
572	Sensory Loss	28	1.4	1.4	no signal
573	Coeliac Disease	34	1.4	1.4	no signal
574	Cold Sweat	61	1.4	1.4	no signal
575	Skin Lesion	94	1.4	1.4	no signal
576	Arthralgia	1,421	1.3	1.4	no signal
577	Blood Pressure Fluctuation	82	1.3	1.3	no signal
578	Incontinence	36	1.3	1.3	no signal
579	Angina Pectoris	98	1.3	1.3	no signal
580	Arteriosclerosis	32	1.3	1.3	no signal
581	Rash Erythematous	159	1.3	1.3	no signal
582	Basal Cell Carcinoma	53	1.3	1.3	no signal
583	Clostridium Difficile Colitis	36	1.3	1.3	no signal
584	Platelet Count Decreased	361	1.3	1.3	no signal
585	Sinus Tachycardia	48	1.3	1.3	no signal
586	Asthenia	1,270	1.3	1.3	no signal
587	Hernia	65	1.3	1.3	no signal
588	Muscle Twitching	78	1.3	1.3	no signal
589	Renal Failure	451	1.3	1.3	no signal
590	Gingival Bleeding	46	1.3	1.3	no signal
591	Covid-19	595	1.3	1.3	no signal
592	Stomatitis	204	1.3	1.3	no signal
593	Blood Thyroid Stimulating Hormone Increased	31	1.3	1.3	no signal
594	Renal Tubular Necrosis	33	1.3	1.3	no signal
595	Respiratory Syncytial Virus Infection	29	1.3	1.3	no signal
596	Blood Pressure Abnormal	66	1.3	1.3	no signal
597	Pain	2,046	1.3	1.3	no signal
598	Oedema	180	1.3	1.3	no signal
599	Joint Dislocation	35	1.3	1.3	no signal
600	Abdominal Pain	772	1.3	1.3	no signal
601	Hypokalaemia	152	1.3	1.3	no signal
602	Depressed Mood	174	1.3	1.3	no signal
603	Fear	89	1.3	1.3	no signal
604	Bronchospasm	47	1.3	1.3	no signal
605	Mental Disorder	143	1.3	1.3	no signal
606	Drug Administration Error	102	1.3	1.3	no signal
607	Macular Degeneration	39	1.3	1.3	no signal
608	Abscess	52	1.3	1.3	no signal
609	Adrenal Insufficiency	39	1.3	1.3	no signal
610	Brain Oedema	41	1.3	1.3	no signal
611	Gastric Disorder	113	1.3	1.3	no signal
612	Foot Deformity	36	1.3	1.3	no signal
613	Joint Stiffness	85	1.3	1.3	no signal
614	Rash Generalised	85	1.3	1.3	no signal
615	Lip Dry	29	1.3	1.3	no signal
616	Drug Prescribing Error	63	1.3	1.3	no signal
617	Tendon Rupture	40	1.3	1.3	no signal
618	Joint Injury	69	1.3	1.3	no signal
619	Sedation	84	1.3	1.3	no signal
620	Fall	1,069	1.3	1.3	no signal
621	Therapy Change	31	1.3	1.3	no signal
622	Leukocytosis	58	1.3	1.3	no signal
623	Deformity	30	1.3	1.3	no signal
624	Grip Strength Decreased	28	1.3	1.3	no signal
625	Haemoglobin Decreased	329	1.3	1.3	no signal
626	Blood Pressure Decreased	212	1.3	1.3	no signal
627	Hypophagia	81	1.3	1.3	no signal
628	Tremor	530	1.3	1.3	no signal
629	Muscular Weakness	360	1.2	1.2	no signal
630	Injection Site Rash	96	1.2	1.2	no signal
631	Injection Site Warmth	65	1.2	1.2	no signal
632	Dysstasia	92	1.2	1.2	no signal
633	Aphasia	95	1.2	1.2	no signal
634	Faeces Discoloured	68	1.2	1.2	no signal
635	Anorexia	41	1.2	1.2	no signal
636	Urinary Retention	104	1.2	1.2	no signal
637	Vaginal Haemorrhage	133	1.2	1.2	no signal
638	Post Procedural Complication	60	1.2	1.2	no signal
639	Suicidal Ideation	285	1.2	1.2	no signal
640	Decreased Appetite	720	1.2	1.2	no signal
641	Renal Disorder	145	1.2	1.2	no signal
642	Eructation	59	1.2	1.2	no signal
643	Bone Disorder	57	1.2	1.2	no signal
644	Personality Change	29	1.2	1.2	no signal
645	Pyrexia	1,071	1.2	1.2	no signal
646	Pneumothorax	49	1.2	1.2	no signal
647	Vaginal Discharge	31	1.2	1.2	no signal
648	Musculoskeletal Disorder	59	1.2	1.2	no signal
649	Road Traffic Accident	129	1.2	1.2	no signal
650	Diplopia	80	1.2	1.2	no signal
651	Petechiae	32	1.2	1.2	no signal
652	Vomiting	1,438	1.2	1.2	no signal
653	Respiratory Disorder	92	1.2	1.2	no signal
654	Dysmenorrhoea	40	1.2	1.2	no signal
655	Alopecia	601	1.2	1.2	no signal
656	Sluggishness	31	1.2	1.2	no signal
657	Gastric Ulcer	58	1.2	1.2	no signal
658	Thinking Abnormal	57	1.2	1.2	no signal
659	Lower Limb Fracture	58	1.2	1.2	no signal
660	Urosepsis	28	1.2	1.2	no signal
661	Injection Site Pruritus	202	1.2	1.2	no signal
662	Cognitive Disorder	141	1.2	1.2	no signal
663	Amnesia	198	1.2	1.2	no signal
664	Pulmonary Arterial Hypertension	44	1.2	1.2	no signal
665	Nightmare	105	1.2	1.2	no signal
666	Small Intestinal Obstruction	37	1.2	1.2	no signal
667	Face Oedema	51	1.2	1.2	no signal
668	Immunodeficiency	44	1.2	1.2	no signal
669	Syncope	299	1.2	1.2	no signal
670	Therapeutic Product Effect Incomplete	210	1.2	1.2	no signal
671	Gait Disturbance	569	1.2	1.2	no signal
672	Pain Of Skin	80	1.2	1.2	no signal
673	Thrombosis	238	1.2	1.2	no signal
674	Eyelid Ptosis	30	1.2	1.2	no signal
675	Metrorrhagia	51	1.2	1.2	no signal
676	Inappropriate Schedule Of Product Administration	521	1.2	1.2	no signal
677	Speech Disorder	154	1.2	1.2	no signal
678	Joint Swelling	354	1.2	1.2	no signal
679	Pulmonary Thrombosis	32	1.2	1.2	no signal
680	Procedural Pain	81	1.2	1.2	no signal
681	Blister	164	1.2	1.2	no signal
682	Memory Impairment	402	1.1	1.2	no signal
683	Skin Exfoliation	242	1.1	1.1	no signal
684	Euphoric Mood	30	1.1	1.1	no signal
685	Skin Haemorrhage	42	1.1	1.1	no signal
686	Feeding Disorder	58	1.1	1.1	no signal
687	Upper Gastrointestinal Haemorrhage	49	1.1	1.1	no signal
688	Mouth Ulceration	61	1.1	1.1	no signal
689	Blood Potassium Increased	47	1.1	1.1	no signal
690	Affect Lability	28	1.1	1.1	no signal
691	Aggression	145	1.1	1.1	no signal
692	Impaired Work Ability	62	1.1	1.1	no signal
693	Skin Disorder	96	1.1	1.1	no signal
694	Diarrhoea Haemorrhagic	27	1.1	1.1	no signal
695	Wrong Technique In Product Usage Process	582	1.1	1.1	no signal
696	Knee Arthroplasty	60	1.1	1.1	no signal
697	Complication Associated With Device	38	1.1	1.1	no signal
698	Malaise	1,263	1.1	1.1	no signal
699	Liver Function Test Increased	61	1.1	1.1	no signal
700	Product Availability Issue	64	1.1	1.1	no signal
701	Transfusion	30	1.1	1.1	no signal
702	Wound Infection	31	1.1	1.1	no signal
703	Full Blood Count Abnormal	30	1.1	1.1	no signal
704	Inflammation	146	1.1	1.1	no signal
705	Musculoskeletal Stiffness	249	1.1	1.1	no signal
706	Hepatomegaly	28	1.1	1.1	no signal
707	Acne	216	1.1	1.1	no signal
708	Skin Irritation	130	1.1	1.1	no signal
709	Hip Arthroplasty	43	1.1	1.1	no signal
710	Oral Herpes	55	1.1	1.1	no signal
711	Hemiparesis	48	1.1	1.1	no signal
712	Surgery	163	1.1	1.1	no signal
713	Restlessness	103	1.1	1.1	no signal
714	Spinal Fracture	56	1.1	1.1	no signal
715	Glomerular Filtration Rate Decreased	34	1.1	1.1	no signal
716	Sepsis	313	1.1	1.1	no signal
717	Hepatic Enzyme Increased	190	1.1	1.1	no signal
718	Wrong Technique In Drug Usage Process	103	1.1	1.1	no signal
719	Disorientation	111	1.1	1.1	no signal
720	Anaemia	533	1.1	1.1	no signal
721	Prescribed Overdose	54	1.1	1.1	no signal
722	Fluid Overload	41	1.1	1.1	no signal
723	Loss Of Consciousness	356	1.1	1.1	no signal
724	Sars-cov-2 Test Positive	37	1.1	1.1	no signal
725	Localised Infection	67	1.1	1.1	no signal
726	Liver Function Test Abnormal	81	1.1	1.1	no signal
727	Alanine Aminotransferase Increased	170	1.1	1.1	no signal
728	Dysarthria	104	1.1	1.1	no signal
729	Menorrhagia	55	1.1	1.1	no signal
730	Abdominal Pain Lower	70	1.1	1.1	no signal
731	Skin Ulcer	71	1.1	1.1	no signal
732	Heart Rate Decreased	97	1.1	1.1	no signal
733	Laboratory Test Abnormal	81	1.1	1.1	no signal
734	Libido Decreased	34	1.1	1.1	no signal
735	Diabetes Mellitus	210	1.1	1.1	no signal
736	Bedridden	36	1.1	1.1	no signal
737	Convulsion	159	1.1	1.1	no signal
738	Post Procedural Haemorrhage	32	1.1	1.1	no signal
739	Gastrointestinal Pain	30	1.1	1.1	no signal
740	Femur Fracture	85	1.1	1.1	no signal
741	Eyelid Oedema	32	1.1	1.1	no signal
742	Tooth Extraction	34	1.1	1.1	no signal
743	Caesarean Section	32	1.1	1.1	no signal
744	Renal Failure Acute	117	1.1	1.1	no signal
745	Product Dose Omission	180	1.1	1.1	no signal
746	Rectal Haemorrhage	117	1.1	1.1	no signal
747	Frequent Bowel Movements	73	1.1	1.1	no signal
748	Skin Burning Sensation	193	1.1	1.1	no signal
749	Injection Site Discomfort	28	1.1	1.1	no signal
750	Underdose	198	1.1	1.1	no signal
751	Blood Lactate Dehydrogenase Increased	43	1.1	1.1	no signal
752	Condition Aggravated	814	1.1	1.1	no signal
753	Aspartate Aminotransferase Increased	143	1.1	1.1	no signal
754	Generalised Oedema	33	1.1	1.1	no signal
755	Product Prescribing Error	63	1.0	1.0	no signal
756	Blood Glucose Decreased	128	1.0	1.0	no signal
757	Drug Dose Omission	445	1.0	1.0	no signal
758	Product Dose Omission Issue	754	1.0	1.0	no signal
759	Coagulopathy	44	1.0	1.0	no signal
760	Tachycardia	235	1.0	1.0	no signal
761	Product Dose Omission In Error	71	1.0	1.0	no signal
762	Therapy Cessation	135	1.0	1.0	no signal
763	Hallucination	198	1.0	1.0	no signal
764	Gastrointestinal Disorder	233	1.0	1.0	no signal
765	Pharmaceutical Product Complaint	69	1.0	1.0	no signal
766	Product Quality Issue	353	1.0	1.0	no signal
767	Intestinal Obstruction	98	1.0	1.0	no signal
768	Adverse Drug Reaction	234	1.0	1.0	no signal
769	Dyskinesia	106	1.0	1.0	no signal
770	Hypotension	523	1.0	1.0	no signal
771	Haematemesis	66	1.0	1.0	no signal
772	Neutrophil Count Decreased	105	1.0	1.0	no signal
773	Aspiration	28	1.0	1.0	no signal
774	Off Label Use	2,231	1.0	1.0	no signal
775	Acute Myocardial Infarction	76	1.0	1.0	no signal
776	Pallor	70	1.0	1.0	no signal
777	Injection Site Erythema	316	1.0	1.0	no signal
778	Blood Creatinine Increased	167	1.0	1.0	no signal
779	Visual Impairment	314	1.0	1.0	no signal
780	Pneumonitis	69	1.0	1.0	no signal
781	Muscle Atrophy	32	1.0	1.0	no signal
782	Mobility Decreased	182	1.0	1.0	no signal
783	Injection Site Swelling	192	1.0	1.0	no signal
784	Lung Disorder	124	1.0	1.0	no signal
785	Intentional Dose Omission	69	1.0	1.0	no signal
786	Product Substitution Issue	145	1.0	1.0	no signal
787	Incorrect Product Administration Duration	51	1.0	1.0	no signal
788	Agitation	185	1.0	1.0	no signal
789	Hyperglycaemia	91	1.0	1.0	no signal
790	Paralysis	36	1.0	1.0	no signal
791	Ejection Fraction Decreased	39	1.0	1.0	no signal
792	Haematochezia	138	1.0	1.0	no signal
793	Loss Of Personal Independence In Daily Activities	119	1.0	1.0	no signal
794	Coma	119	1.0	1.0	no signal
795	Injection Site Bruising	196	1.0	1.0	no signal
796	Spinal Operation	30	1.0	1.0	no signal
797	Spinal Pain	29	1.0	1.0	no signal
798	Appendicitis	23	1.0	1.0	no signal
799	Blood Bilirubin Increased	67	1.0	1.0	no signal
800	Product Packaging Quantity Issue	27	1.0	1.0	no signal
801	Knee Operation	24	1.0	1.0	no signal
802	Joint Range Of Motion Decreased	33	1.0	1.0	no signal
803	Bacteraemia	29	1.0	1.0	no signal
804	Psoriasis	322	1.0	1.0	no signal
805	Confusional State	398	1.0	1.0	no signal
806	Injection Site Nodule	27	1.0	1.0	no signal
807	Tubulointerstitial Nephritis	46	1.0	1.0	no signal
808	Grand Mal Convulsion	23	1.0	1.0	no signal
809	Therapy Non-responder	109	1.0	1.0	no signal
810	Infection	352	1.0	1.0	no signal
811	Psoriatic Arthropathy	98	1.0	1.0	no signal
812	Ataxia	29	1.0	1.0	no signal
813	Emotional Distress	295	1.0	1.0	no signal
814	Colitis	91	0.9	0.9	no signal
815	Intraocular Pressure Increased	31	0.9	0.9	no signal
816	Ventricular Tachycardia	40	0.9	0.9	no signal
817	Cardiac Disorder	226	0.9	0.9	no signal
818	Gait Inability	79	0.9	0.9	no signal
819	Movement Disorder	77	0.9	0.9	no signal
820	Incorrect Drug Administration Duration	68	0.9	0.9	no signal
821	Impaired Driving Ability	27	0.9	0.9	no signal
822	Diabetes Mellitus Inadequate Control	42	0.9	0.9	no signal
823	Deafness	62	0.9	0.9	no signal
824	Haematuria	81	0.9	0.9	no signal
825	Myocardial Ischaemia	27	0.9	0.9	no signal
826	Poor Quality Product Administered	24	0.9	0.9	no signal
827	Cyanosis	37	0.9	0.9	no signal
828	Pancreatitis	124	0.9	0.9	no signal
829	Ventricular Fibrillation	26	0.9	0.9	no signal
830	Squamous Cell Carcinoma	22	0.9	0.9	no signal
831	Arrhythmia	111	0.9	0.9	no signal
832	Obstructive Airways Disorder	26	0.9	0.9	no signal
833	Plasma Cell Myeloma	91	0.9	0.9	no signal
834	Dermatitis Allergic	29	0.9	0.9	no signal
835	Drug Eruption	41	0.9	0.9	no signal
836	Disability	46	0.9	0.9	no signal
837	Folliculitis	24	0.9	0.9	no signal
838	Metastases To Bone	38	0.9	0.9	no signal
839	Skin Cancer	50	0.9	0.9	no signal
840	Injection Site Induration	30	0.9	0.9	no signal
841	C-reactive Protein Increased	84	0.9	0.9	no signal
842	Glycosylated Haemoglobin Increased	58	0.9	0.9	no signal
843	Pulmonary Oedema	103	0.9	0.9	no signal
844	Intentional Product Use Issue	202	0.9	0.9	no signal
845	Acute Kidney Injury	349	0.9	0.9	no signal
846	Motor Dysfunction	23	0.9	0.9	no signal
847	Disease Recurrence	108	0.9	0.9	no signal
848	Gastrointestinal Haemorrhage	190	0.9	0.9	no signal
849	Device Dislocation	98	0.9	0.9	no signal
850	Muscle Spasticity	28	0.9	0.9	no signal
851	Respiratory Distress	62	0.9	0.9	no signal
852	Injection Site Pain	681	0.9	0.9	no signal
853	Visual Acuity Reduced	75	0.9	0.9	no signal
854	Inability To Afford Medication	22	0.9	0.9	no signal
855	Hypomagnesaemia	31	0.9	0.9	no signal
856	Abasia	56	0.9	0.9	no signal
857	Embedded Device	22	0.9	0.9	no signal
858	Seizure	256	0.9	0.9	no signal
859	Rheumatoid Arthritis	252	0.9	0.9	no signal
860	Poor Venous Access	23	0.9	0.9	no signal
861	Intentional Product Misuse	193	0.9	0.9	no signal
862	Menstruation Delayed	23	0.9	0.9	no signal
863	Osteonecrosis Of Jaw	55	0.9	0.9	no signal
864	Ileus	27	0.9	0.9	no signal
865	Arthropathy	122	0.9	0.9	no signal
866	Hip Fracture	70	0.9	0.9	no signal
867	Respiratory Failure	159	0.9	0.9	no signal
868	Sensory Disturbance	35	0.9	0.9	no signal
869	Neoplasm	25	0.9	0.9	no signal
870	Central Nervous System Lesion	30	0.9	0.9	no signal
871	Injection Site Reaction	148	0.8	0.8	no signal
872	Drug Level Decreased	22	0.8	0.8	no signal
873	Hallucination, Visual	45	0.8	0.8	no signal
874	Therapeutic Product Effect Decreased	95	0.8	0.8	no signal
875	Unresponsive To Stimuli	55	0.8	0.8	no signal
876	Apathy	31	0.8	0.8	no signal
877	Nephropathy	20	0.8	0.8	no signal
878	Haemorrhage	222	0.8	0.8	no signal
879	Hypercalcaemia	26	0.8	0.8	no signal
880	Mydriasis	27	0.8	0.8	no signal
881	Salivary Hypersecretion	21	0.8	0.8	no signal
882	Application Site Pain	46	0.8	0.8	no signal
883	Device Occlusion	29	0.8	0.8	no signal
884	Myocardial Infarction	366	0.8	0.8	no signal
885	Menstruation Irregular	55	0.8	0.8	no signal
886	Mania	34	0.8	0.8	no signal
887	Delusion	32	0.8	0.8	no signal
888	Retinal Detachment	19	0.8	0.8	no signal
889	Sinus Bradycardia	20	0.8	0.8	no signal
890	Lymphoma	32	0.8	0.8	no signal
891	Withdrawal Syndrome	87	0.8	0.8	no signal
892	Multiple Sclerosis	99	0.8	0.8	no signal
893	Blindness Unilateral	29	0.8	0.8	no signal
894	Sudden Death	22	0.8	0.8	no signal
895	Injection Site Irritation	26	0.8	0.8	no signal
896	Liver Disorder	91	0.8	0.8	no signal
897	Application Site Erythema	54	0.8	0.8	no signal
898	Hypoacusis	88	0.8	0.8	no signal
899	Fistula	23	0.8	0.8	no signal
900	Pulmonary Fibrosis	39	0.8	0.8	no signal
901	Haematoma	53	0.8	0.8	no signal
902	Febrile Neutropenia	134	0.8	0.8	no signal
903	Subdural Haematoma	29	0.8	0.8	no signal
904	Covid-19 Pneumonia	24	0.8	0.8	no signal
905	Cerebrovascular Accident	343	0.8	0.8	no signal
906	Accident	24	0.8	0.8	no signal
907	Blindness	82	0.8	0.8	no signal
908	Orthostatic Hypotension	35	0.8	0.8	no signal
909	Brain Injury	20	0.8	0.8	no signal
910	Erectile Dysfunction	51	0.8	0.8	no signal
911	Disease Progression	233	0.8	0.8	no signal
912	Drug Intolerance	190	0.8	0.8	no signal
913	Vasculitis	23	0.8	0.8	no signal
914	Helicobacter Infection	20	0.8	0.8	no signal
915	Bone Density Decreased	62	0.8	0.8	no signal
916	Application Site Rash	27	0.8	0.8	no signal
917	Product Administration Error	39	0.8	0.8	no signal
918	Multiple Sclerosis Relapse	135	0.8	0.8	no signal
919	Nervous System Disorder	61	0.8	0.8	no signal
920	Malignant Melanoma	26	0.8	0.8	no signal
921	Breast Cancer Female	52	0.8	0.8	no signal
922	Adverse Event	177	0.8	0.8	no signal
923	Lower Respiratory Tract Infection	87	0.8	0.8	no signal
924	Skin Reaction	27	0.8	0.8	no signal
925	Encephalopathy	47	0.8	0.8	no signal
926	Blood Glucose Fluctuation	21	0.8	0.8	no signal
927	Eye Inflammation	18	0.7	0.7	no signal
928	Wound	53	0.7	0.7	no signal
929	Metastases To Lung	22	0.7	0.7	no signal
930	Hypoglycaemia	92	0.7	0.7	no signal
931	Hypotonia	19	0.7	0.7	no signal
932	Sexual Dysfunction	22	0.7	0.7	no signal
933	Pregnancy	38	0.7	0.7	no signal
934	International Normalised Ratio Increased	54	0.7	0.7	no signal
935	Injection Site Mass	69	0.7	0.7	no signal
936	Ascites	55	0.7	0.7	no signal
937	Dementia	52	0.7	0.7	no signal
938	Blood Glucose Increased	351	0.7	0.7	no signal
939	Device Malfunction	124	0.7	0.7	no signal
940	Psychotic Disorder	54	0.7	0.7	no signal
941	Electrolyte Imbalance	21	0.7	0.7	no signal
942	No Adverse Event	323	0.7	0.7	no signal
943	Tooth Loss	38	0.7	0.7	no signal
944	Application Site Pruritus	41	0.7	0.7	no signal
945	Gamma-glutamyltransferase Increased	40	0.7	0.7	no signal
946	Exposure During Pregnancy	112	0.7	0.7	no signal
947	Acute Myeloid Leukaemia	28	0.7	0.7	no signal
948	Pancytopenia	100	0.7	0.7	no signal
949	Colitis Ulcerative	80	0.7	0.7	no signal
950	Metastases To Liver	31	0.7	0.7	no signal
951	Application Site Irritation	22	0.7	0.7	no signal
952	Anaphylactic Shock	45	0.7	0.7	no signal
953	Device Issue	153	0.7	0.7	no signal
954	Prostatic Specific Antigen Increased	24	0.7	0.7	no signal
955	Mental Impairment	42	0.7	0.7	no signal
956	Cerebral Infarction	42	0.7	0.7	no signal
957	Shock	39	0.7	0.7	no signal
958	Leukaemia	16	0.7	0.7	no signal
959	Hallucination, Auditory	27	0.7	0.7	no signal
960	Suicide Attempt	103	0.7	0.7	no signal
961	Drug Exposure During Pregnancy	58	0.7	0.7	no signal
962	Myoclonus	20	0.7	0.7	no signal
963	Colon Cancer	25	0.7	0.7	no signal
964	Cytopenia	20	0.7	0.7	no signal
965	Diabetic Ketoacidosis	40	0.7	0.7	no signal
966	Hepatic Cirrhosis	31	0.7	0.7	no signal
967	Myelodysplastic Syndrome	24	0.7	0.7	no signal
968	Hypokinesia	24	0.6	0.6	no signal
969	Generalised Tonic-clonic Seizure	27	0.6	0.6	no signal
970	Mucosal Inflammation	43	0.6	0.6	no signal
971	Sickle Cell Anaemia With Crisis	26	0.6	0.6	no signal
972	Metastases To Central Nervous System	21	0.6	0.6	no signal
973	Injection Site Haemorrhage	130	0.6	0.6	no signal
974	Therapy Interrupted	113	0.6	0.6	no signal
975	Exposure Via Skin Contact	37	0.6	0.6	no signal
976	Brain Neoplasm	15	0.6	0.6	no signal
977	Palmar-plantar Erythrodysaesthesia Syndrome	38	0.6	0.6	no signal
978	Drug Dispensing Error	25	0.6	0.6	no signal
979	Injection Site Discolouration	20	0.6	0.6	no signal
980	Ankylosing Spondylitis	21	0.6	0.6	no signal
981	Systemic Lupus Erythematosus	57	0.6	0.6	no signal
982	Hyperkalaemia	56	0.6	0.6	no signal
983	Medication Error	89	0.6	0.6	no signal
984	Ill-defined Disorder	97	0.6	0.6	no signal
985	Internal Haemorrhage	18	0.6	0.6	no signal
986	Hyponatraemia	88	0.6	0.6	no signal
987	Amenorrhoea	26	0.6	0.6	no signal
988	Tachypnoea	21	0.6	0.6	no signal
989	Treatment Noncompliance	84	0.6	0.6	no signal
990	Decreased Immune Responsiveness	15	0.6	0.6	no signal
991	General Physical Health Deterioration	175	0.6	0.6	no signal
992	Tardive Dyskinesia	43	0.6	0.6	no signal
993	Multiple Fractures	25	0.6	0.6	no signal
994	Blood Creatine Phosphokinase Increased	44	0.6	0.6	no signal
995	Prescribed Underdose	30	0.6	0.6	no signal
996	Melaena	33	0.6	0.6	no signal
997	Device Delivery System Issue	39	0.6	0.6	no signal
998	Breast Cancer Metastatic	16	0.6	0.6	no signal
999	Rash Maculo-papular	33	0.6	0.6	no signal
1000	Jaundice	40	0.6	0.6	no signal
1001	Pancreatitis Acute	33	0.6	0.6	no signal
1002	Accidental Exposure To Product	147	0.6	0.6	no signal
1003	Renal Impairment	123	0.6	0.6	no signal
1004	Therapy Partial Responder	22	0.6	0.6	no signal
1005	Contraindicated Product Administered	44	0.6	0.6	no signal
1006	Hospitalisation	221	0.6	0.6	no signal
1007	Stevens-johnson Syndrome	32	0.6	0.6	no signal
1008	Needle Issue	41	0.6	0.6	no signal
1009	Injection Site Haematoma	21	0.6	0.6	no signal
1010	Maternal Exposure During Pregnancy	126	0.6	0.6	no signal
1011	Incorrect Route Of Product Administration	24	0.6	0.6	no signal
1012	Incorrect Product Storage	19	0.6	0.6	no signal
1013	Neoplasm Progression	50	0.6	0.6	no signal
1014	Intestinal Perforation	16	0.6	0.6	no signal
1015	Thrombocytopenia	158	0.6	0.6	no signal
1016	Rebound Effect	16	0.6	0.6	no signal
1017	Dialysis	20	0.6	0.6	no signal
1018	Bradycardia	74	0.5	0.5	no signal
1019	Septic Shock	60	0.5	0.5	no signal
1020	Fracture	26	0.5	0.5	no signal
1021	Cardiovascular Disorder	35	0.5	0.5	no signal
1022	Electrocardiogram Qt Prolonged	49	0.5	0.5	no signal
1023	Osteonecrosis	45	0.5	0.5	no signal
1024	Cardiac Failure	109	0.5	0.5	no signal
1025	Drug Interaction	215	0.5	0.5	no signal
1026	Product Preparation Error	28	0.5	0.5	no signal
1027	Complication Of Device Insertion	25	0.5	0.5	no signal
1028	Abortion Spontaneous	54	0.5	0.5	no signal
1029	Product Dispensing Error	29	0.5	0.5	no signal
1030	Hypocalcaemia	25	0.5	0.5	no signal
1031	Thyroid Cancer	16	0.5	0.5	no signal
1032	Bone Loss	20	0.5	0.5	no signal
1033	Hepatitis C	16	0.5	0.5	no signal
1034	Drug Administered At Inappropriate Site	14	0.5	0.5	no signal
1035	Drug Toxicity	18	0.5	0.5	no signal
1036	Altered State Of Consciousness	28	0.5	0.5	no signal
1037	Device Breakage	51	0.5	0.5	no signal
1038	Complication Of Device Removal	22	0.5	0.5	no signal
1039	Ovarian Cancer	12	0.5	0.5	no signal
1040	Neoplasm Malignant	86	0.5	0.5	no signal
1041	Hepatitis	33	0.5	0.5	no signal
1042	Intentional Self-injury	26	0.5	0.5	no signal
1043	Neutropenia	174	0.5	0.5	no signal
1044	Extrapyramidal Disorder	32	0.5	0.5	no signal
1045	Subarachnoid Haemorrhage	13	0.5	0.5	no signal
1046	Device Use Issue	22	0.5	0.5	no signal
1047	Interstitial Lung Disease	61	0.5	0.5	no signal
1048	Hyperbilirubinaemia	13	0.5	0.5	no signal
1049	Transaminases Increased	28	0.5	0.5	no signal
1050	Cerebral Haemorrhage	45	0.5	0.5	no signal
1051	Hyperthyroidism	18	0.5	0.5	no signal
1052	Delirium	43	0.5	0.5	no signal
1053	Blood Glucose Abnormal	23	0.5	0.5	no signal
1054	Hepatic Function Abnormal	46	0.5	0.5	no signal
1055	Proteinuria	23	0.5	0.5	no signal
1056	Multi-organ Failure	21	0.5	0.5	no signal
1057	Cardiogenic Shock	17	0.5	0.5	no signal
1058	Depressed Level Of Consciousness	47	0.5	0.5	no signal
1059	Product Adhesion Issue	42	0.5	0.5	no signal
1060	Inappropriate Antidiuretic Hormone Secretion	12	0.5	0.5	no signal
1061	Breast Cancer	108	0.5	0.4	no signal
1062	Epilepsy	35	0.5	0.4	no signal
1063	Hepatic Failure	34	0.4	0.4	no signal
1064	Gastric Haemorrhage	13	0.4	0.4	no signal
1065	Malignant Neoplasm Progression	114	0.4	0.4	no signal
1066	Uveitis	15	0.4	0.4	no signal
1067	Cardiac Arrest	92	0.4	0.4	no signal
1068	Leukopenia	55	0.4	0.4	no signal
1069	Cytokine Release Syndrome	21	0.4	0.4	no signal
1070	Drug Withdrawal Syndrome	97	0.4	0.4	no signal
1071	Cardio-respiratory Arrest	46	0.4	0.4	no signal
1072	Device Leakage	46	0.4	0.4	no signal
1073	Agranulocytosis	20	0.4	0.4	no signal
1074	Pericarditis	18	0.4	0.4	no signal
1075	Dystonia	21	0.4	0.4	no signal
1076	Hypertensive Crisis	12	0.4	0.4	no signal
1077	Erythema Multiforme	10	0.4	0.4	no signal
1078	Hepatic Encephalopathy	10	0.4	0.4	no signal
1079	Schizophrenia	13	0.4	0.4	no signal
1080	Haemorrhage Intracranial	16	0.4	0.4	no signal
1081	Serotonin Syndrome	20	0.4	0.4	no signal
1082	Intentional Drug Misuse	22	0.4	0.4	no signal
1083	Parkinsonism	10	0.4	0.4	no signal
1084	Neuroleptic Malignant Syndrome	12	0.4	0.4	no signal
1085	Ischaemic Stroke	18	0.4	0.4	no signal
1086	Muscle Rigidity	12	0.4	0.4	no signal
1087	Product Complaint	25	0.4	0.4	no signal
1088	Device Use Error	34	0.4	0.4	no signal
1089	Toxic Skin Eruption	10	0.4	0.4	no signal
1090	Eosinophilia	17	0.4	0.4	no signal
1091	Injection Site Extravasation	12	0.4	0.4	no signal
1092	Skeletal Injury	10	0.4	0.4	no signal
1093	Metabolic Acidosis	30	0.4	0.4	no signal
1094	Incorrect Dose Administered By Device	24	0.4	0.4	no signal
1095	Lung Neoplasm Malignant	39	0.4	0.4	no signal
1096	Cholestasis	18	0.4	0.4	no signal
1097	Premature Delivery	15	0.4	0.4	no signal
1098	Bone Marrow Failure	19	0.4	0.4	no signal
1099	Acute Respiratory Distress Syndrome	16	0.4	0.4	no signal
1100	Hypothermia	9	0.3	0.3	no signal
1101	Synovitis	16	0.3	0.3	no signal
1102	Akathisia	12	0.3	0.3	no signal
1103	Drug-induced Liver Injury	27	0.3	0.3	no signal
1104	Drug Dose Omission By Device	67	0.3	0.3	no signal
1105	Device Defective	14	0.3	0.3	no signal
1106	Toxic Epidermal Necrolysis	13	0.3	0.3	no signal
1107	Drug Resistance	22	0.3	0.3	no signal
1108	Genital Haemorrhage	11	0.3	0.3	no signal
1109	Polyneuropathy	10	0.3	0.3	no signal
1110	Death	721	0.3	0.3	no signal
1111	Respiratory Arrest	23	0.3	0.3	no signal
1112	Peritonitis	17	0.3	0.3	no signal
1113	Circulatory Collapse	14	0.3	0.3	no signal
1114	Syringe Issue	14	0.3	0.3	no signal
1115	Wrong Technique In Device Usage Process	36	0.3	0.3	no signal
1116	Liver Injury	19	0.3	0.3	no signal
1117	Disseminated Intravascular Coagulation	11	0.3	0.3	no signal
1118	Unintentional Medical Device Removal	9	0.3	0.3	no signal
1119	Rhabdomyolysis	32	0.3	0.3	no signal
1120	Device Expulsion	49	0.3	0.3	no signal
1121	Incorrect Route Of Drug Administration	27	0.3	0.3	no signal
1122	Drug Level Increased	12	0.3	0.3	no signal
1123	Cytomegalovirus Infection	12	0.3	0.3	no signal
1124	Multiple Organ Dysfunction Syndrome	20	0.3	0.3	no signal
1125	Myocarditis	8	0.3	0.3	no signal
1126	Respiratory Depression	8	0.3	0.3	no signal
1127	Abnormal Weight Gain	8	0.3	0.3	no signal
1128	Abortion Induced	6	0.2	0.2	no signal
1129	Poisoning	8	0.2	0.2	no signal
1130	Hepatotoxicity	14	0.2	0.2	no signal
1131	Premature Baby	19	0.2	0.2	no signal
1132	Nephropathy Toxic	7	0.2	0.2	no signal
1133	Treatment Failure	51	0.2	0.2	no signal
1134	Injury Associated With Device	12	0.2	0.2	no signal
1135	Peritonitis Bacterial	6	0.2	0.2	no signal
1136	Device Deployment Issue	7	0.2	0.2	no signal
1137	Unintended Pregnancy	6	0.2	0.2	no signal
1138	Product Administered At Inappropriate Site	10	0.2	0.2	no signal
1139	Hepatic Cancer	13	0.2	0.2	no signal
1140	Hand Deformity	7	0.2	0.2	no signal
1141	Status Epilepticus	6	0.2	0.2	no signal
1142	Lactic Acidosis	17	0.2	0.2	no signal
1143	Product Storage Error	45	0.2	0.2	no signal
1144	Intentional Overdose	33	0.2	0.2	no signal
1145	Acute Hepatic Failure	7	0.2	0.2	no signal
1146	Pneumocystis Jirovecii Pneumonia	5	0.2	0.2	no signal
1147	Lymphopenia	7	0.2	0.2	no signal
1148	Device Difficult To Use	32	0.2	0.2	no signal
1149	Meningioma	7	0.2	0.2	no signal
1150	Prostate Cancer	38	0.2	0.2	no signal
1151	Neurotoxicity	8	0.2	0.2	no signal
1152	Foetal Exposure During Pregnancy	37	0.2	0.2	no signal
1153	Gastric Cancer	11	0.2	0.2	no signal
1154	Pancreatic Carcinoma	12	0.2	0.2	no signal
1155	Accidental Underdose	6	0.2	0.2	no signal
1156	Device Adhesion Issue	6	0.2	0.2	no signal
1157	Device Mechanical Issue	5	0.2	0.2	no signal
1158	Drug Dependence	62	0.1	0.1	no signal
1159	Completed Suicide	30	0.1	0.1	no signal
1160	Toxicity To Various Agents	56	0.1	0.1	no signal
1161	Gynaecomastia	10	0.1	0.1	no signal
1162	Renal Cancer	14	0.1	0.1	no signal
1163	Drug Reaction With Eosinophilia And Systemic Symptoms	7	0.1	0.1	no signal
1164	Drug Abuse	20	0.1	0.1	no signal
1165	Bladder Cancer	14	0.1	0.1	no signal
1166	Tuberculosis	3	0.1	0.1	no signal
1167	Dependence	10	0.1	0.1	no signal
1168	Oesophageal Carcinoma	5	0.1	0.1	no signal