Reaction
Vulvovaginal Discomfort reporting signals
As of the last recalculation, Vulvovaginal Discomfort appears in 4,348 FAERS reports alongside 32 co-occurring drug terms. The strongest observed disproportionality signal is MICONAZOLE NITRATE (PRR 282.0).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Miconazole Nitrate | 460 | 282.0 | 297.8 |
| Etonogestrel And Ethinyl Estradiol | 267 | 61.3 | 62.1 |
| Estradiol | 745 | 49.6 | 50.0 |
| Conjugated Estrogens | 288 | 25.3 | 25.4 |
| Estrogens, Conjugated | 289 | 24.9 | 25.0 |
| Estradiol Gel 0.1% | 164 | 18.0 | 18.1 |
| Estradiol Transdermal | 164 | 18.0 | 18.1 |
| Copper | 145 | 16.6 | 16.7 |
| Progesterone | 42 | 8.9 | 8.9 |
| Drs. Clotrimazole | 19 | 7.9 | 7.9 |
| Family Wellness Clotrimazole | 19 | 7.9 | 7.9 |
| Clotrimazole Topical | 19 | 7.9 | 7.9 |
| Clotrimazole | 19 | 7.4 | 7.4 |
| Levonorgestrel | 276 | 6.9 | 6.9 |
| Tranexamic Acid | 10 | 5.4 | 5.4 |
| Empagliflozin | 58 | 4.2 | 4.2 |
| Biotin | 27 | 4.2 | 4.2 |
| Lubiprostone | 8 | 4.1 | 4.1 |
| Nitrofurantoin | 13 | 3.8 | 3.8 |
| Nitrofurantoin (Monohydrate/Macrocrystals) | 13 | 3.7 | 3.7 |
| Clobetasol Propionate Ointment Usp, 0.05% | 8 | 3.7 | 3.7 |
| Anastrozole | 28 | 3.7 | 3.7 |
| Anastrozole Tablets | 15 | 3.4 | 3.4 |
| Canagliflozin | 20 | 3.2 | 3.2 |
| Gefitinib | 6 | 3.2 | 3.2 |
| Oxybutynin | 18 | 3.0 | 3.0 |
| Dapagliflozin | 18 | 2.7 | 2.7 |
| Ribociclib | 17 | 2.6 | 2.6 |
| Multivitamin | 26 | 2.5 | 2.5 |
| Conjugated Estrogens And Medroxyprogesterone Acetate | 11 | 2.2 | 2.2 |
| Etonogestrel | 18 | 1.8 | 1.8 |
| Drospirenone And Ethinyl Estradiol | 13 | 1.4 | 1.4 |