OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Ibuprofen And Diphenhydramine Citrate

1,175 flagged reaction(s) · 102,294 total co-reports · max PRR 434.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Red Blood Cell Sedimentation Rate 91 434.7 436.4 signal
2 Deafness Transitory 145 184.8 185.9 signal
3 Granuloma Skin 96 118.8 119.3 signal
4 Enthesopathy 160 102.3 103.0 signal
5 Blood Parathyroid Hormone Decreased 110 72.1 72.5 signal
6 Tenosynovitis 166 57.9 58.3 signal
7 Alanine Aminotransferase Abnormal 115 52.5 52.8 signal
8 Panniculitis 114 44.9 45.2 signal
9 Shoulder Arthroplasty 116 41.4 41.6 signal
10 Rheumatoid Nodule 118 40.1 40.3 signal
11 Product Name Confusion 46 39.7 39.7 signal
12 Cholecystitis Chronic 284 39.6 40.0 signal
13 Gallbladder Cholesterolosis 19 38.9 39.0 signal
14 Biliary Dyskinesia 65 35.7 35.8 signal
15 Rheumatoid Lung 33 32.1 32.2 signal
16 Drug Effect Prolonged 16 26.7 26.7 signal
17 Gallbladder Non-functioning 16 25.9 25.9 signal
18 Product Difficult To Swallow 28 25.3 25.3 signal
19 Thrombophlebitis Superficial 81 24.5 24.5 signal
20 Tongue Disorder 177 22.5 22.7 signal
21 C-reactive Protein Abnormal 153 22.1 22.3 signal
22 Gallbladder Injury 45 21.5 21.5 signal
23 Superior Sagittal Sinus Thrombosis 18 20.6 20.6 signal
24 Functional Gastrointestinal Disorder 77 20.6 20.6 signal
25 Skin Necrosis 111 19.7 19.8 signal
26 Pharyngitis 255 18.9 19.1 signal
27 Pelvic Venous Thrombosis 28 17.9 17.9 signal
28 Drug Tolerance Decreased 53 17.5 17.5 signal
29 Foreign Body In Respiratory Tract 24 16.7 16.7 signal
30 Foot Operation 89 16.7 16.7 signal
31 Uterine Perforation 154 16.6 16.7 signal
32 Left Atrial Dilatation 23 16.5 16.5 signal
33 Gastrointestinal Pain 192 16.1 16.3 signal
34 Intracranial Venous Sinus Thrombosis 19 16.1 16.1 signal
35 Pulmonary Infarction 41 15.8 15.9 signal
36 Lumbar Radiculopathy 19 15.0 15.0 signal
37 Hangover 47 12.2 12.2 signal
38 Granuloma 45 11.9 12.0 signal
39 Tendonitis 202 11.9 12.0 signal
40 Fear Of Disease 23 11.7 11.7 signal
41 Foreign Body 49 11.1 11.1 signal
42 Osteosclerosis 19 11.0 11.0 signal
43 Pelvic Inflammatory Disease 18 11.0 11.0 signal
44 Drug Tolerance 61 11.0 11.0 signal
45 Biliary Colic 34 10.8 10.9 signal
46 Medical Device Pain 25 10.6 10.6 signal
47 Erection Increased 49 10.6 10.6 signal
48 Cholecystitis Acute 62 10.0 10.1 signal
49 Ulcer 173 9.9 10.0 signal
50 Ear Infection 284 9.8 9.9 signal
51 Gallbladder Disorder 187 9.6 9.6 signal
52 Hypercalcaemia 126 9.3 9.4 signal
53 Medical Device Discomfort 31 9.2 9.2 signal
54 Injury 708 9.2 9.4 signal
55 Musculoskeletal Disorder 190 9.1 9.1 signal
56 Acute Sinusitis 17 9.0 9.0 signal
57 Drug Effective For Unapproved Indication 287 9.0 9.1 signal
58 Spinal Osteoarthritis 84 8.7 8.7 signal
59 Red Blood Cell Sedimentation Rate Increased 102 8.4 8.4 signal
60 Synovitis 164 8.3 8.4 signal
61 Jugular Vein Thrombosis 16 8.3 8.3 signal
62 Drug Effect Delayed 41 8.1 8.2 signal
63 Fear Of Injection 62 8.1 8.1 signal
64 Bone Lesion 32 8.1 8.1 signal
65 Deep Vein Thrombosis 566 7.9 8.1 signal
66 Abnormal Loss Of Weight 58 7.8 7.8 signal
67 Essential Hypertension 22 7.8 7.8 signal
68 Cholelithiasis 274 7.6 7.7 signal
69 Osteolysis 17 7.6 7.6 signal
70 Drug Screen False Positive 23 7.5 7.5 signal
71 Basal Cell Carcinoma 128 7.5 7.5 signal
72 Accidental Exposure To Product By Child 53 7.1 7.1 signal
73 Aortic Arteriosclerosis 20 7.1 7.1 signal
74 Wrong Drug Administered 70 7.1 7.1 signal
75 Product Size Issue 41 7.0 7.0 signal
76 Psychological Trauma 67 7.0 7.0 signal
77 Hypophagia 193 6.9 7.0 signal
78 Carotid Artery Stenosis 26 6.8 6.8 signal
79 Atelectasis 71 6.7 6.7 signal
80 Blood Pressure Systolic Abnormal 18 6.6 6.6 signal
81 Poor Quality Drug Administered 47 6.5 6.5 signal
82 Hyperparathyroidism Secondary 18 6.5 6.5 signal
83 Ventricular Hypertrophy 18 6.5 6.5 signal
84 Adverse Reaction 94 6.5 6.5 signal
85 Temporomandibular Joint Syndrome 19 6.4 6.4 signal
86 Intervertebral Disc Degeneration 65 6.4 6.4 signal
87 Pre-existing Condition Improved 44 6.4 6.4 signal
88 Energy Increased 41 6.3 6.3 signal
89 Snoring 26 6.3 6.3 signal
90 Diabetic Neuropathy 34 6.2 6.2 signal
91 Tricuspid Valve Incompetence 53 6.1 6.1 signal
92 Blood Pressure Diastolic Abnormal 17 6.0 6.0 signal
93 Drug Eruption 116 6.0 6.0 signal
94 Feeding Disorder 129 5.9 5.9 signal
95 Diverticulum 46 5.8 5.8 signal
96 Cholecystitis 75 5.7 5.8 signal
97 Rhinitis Allergic 28 5.7 5.7 signal
98 Anhedonia 166 5.7 5.7 signal
99 Deafness 164 5.7 5.7 signal
100 Generalised Erythema 36 5.7 5.7 signal
101 Fear 168 5.6 5.7 signal
102 Cholecystectomy 70 5.6 5.6 signal
103 Pulmonary Embolism 588 5.6 5.7 signal
104 Lumbar Spinal Stenosis 18 5.6 5.6 signal
105 Neck Injury 18 5.6 5.6 signal
106 Peptic Ulcer 20 5.5 5.5 signal
107 Product Administered To Patient Of Inappropriate Age 36 5.5 5.5 signal
108 Nephrogenic Anaemia 28 5.5 5.5 signal
109 Non-cardiac Chest Pain 19 5.4 5.4 signal
110 Metastases To Spine 20 5.4 5.4 signal
111 Skin Ulcer 154 5.4 5.5 signal
112 Flank Pain 55 5.4 5.4 signal
113 Post-traumatic Stress Disorder 39 5.3 5.3 signal
114 Screaming 37 5.3 5.3 signal
115 Gastric Ulcer 110 5.3 5.3 signal
116 Otitis Media 19 5.2 5.2 signal
117 Restless Legs Syndrome 104 5.2 5.2 signal
118 Hyperlipidaemia 67 5.1 5.1 signal
119 Varicose Vein 29 5.1 5.1 signal
120 Intervertebral Disc Disorder 24 5.1 5.1 signal
121 Drug Screen Positive 44 5.1 5.1 signal
122 Joint Injury 119 5.1 5.1 signal
123 Drug Hypersensitivity 1,045 4.9 5.1 signal
124 Blood Pressure Systolic Increased 105 4.9 4.9 signal
125 Major Depression 38 4.7 4.7 signal
126 Eating Disorder 110 4.7 4.7 signal
127 Gastric Haemorrhage 59 4.6 4.6 signal
128 Decreased Interest 30 4.6 4.6 signal
129 Anxiety Disorder 17 4.6 4.6 signal
130 Supraventricular Extrasystoles 17 4.6 4.6 signal
131 Obsessive-compulsive Disorder 40 4.5 4.5 signal
132 Cardiac Murmur 43 4.5 4.5 signal
133 Benign Prostatic Hyperplasia 25 4.4 4.4 signal
134 Arthropathy 269 4.4 4.4 signal
135 Feeling Jittery 92 4.4 4.4 signal
136 Drug Administered To Patient Of Inappropriate Age 35 4.4 4.4 signal
137 Aspartate Aminotransferase Increased 254 4.4 4.4 signal
138 Cardiomegaly 59 4.3 4.3 signal
139 Synovial Cyst 22 4.3 4.3 signal
140 Psoriatic Arthropathy 190 4.3 4.3 signal
141 Mitral Valve Incompetence 53 4.3 4.3 signal
142 Hiatus Hernia 60 4.2 4.2 signal
143 Tenderness 48 4.2 4.2 signal
144 Spinal Column Stenosis 22 4.2 4.2 signal
145 Epigastric Discomfort 18 4.2 4.2 signal
146 Difficulty In Walking 16 4.2 4.2 signal
147 Blood Pressure Diastolic Increased 21 4.1 4.1 signal
148 Heart Disease Congenital 16 4.1 4.1 signal
149 Rales 26 4.1 4.1 signal
150 Aortic Valve Incompetence 19 4.0 4.0 signal
151 Drug Effect Incomplete 164 4.0 4.1 signal
152 Left Ventricular Hypertrophy 19 4.0 4.0 signal
153 Angina Unstable 29 4.0 4.0 signal
154 Osteomyelitis 80 4.0 4.0 signal
155 Musculoskeletal Discomfort 76 4.0 4.0 signal
156 Spondylitis 16 4.0 4.0 signal
157 Pelvic Pain 80 4.0 4.0 signal
158 Scoliosis 27 4.0 4.0 signal
159 Gastritis 114 3.9 4.0 signal
160 Activities Of Daily Living Impaired 87 3.9 3.9 signal
161 Osteopenia 66 3.9 3.9 signal
162 Gastric Disorder 150 3.9 3.9 signal
163 Maternal Exposure Timing Unspecified 16 3.9 3.9 signal
164 Ulcer Haemorrhage 29 3.9 3.9 signal
165 Exostosis 39 3.9 3.9 signal
166 Haemorrhagic Anaemia 19 3.9 3.9 signal
167 Arteriosclerosis 40 3.9 3.9 signal
168 Emotional Distress 514 3.8 3.9 signal
169 Stomach Discomfort 22 3.8 3.8 signal
170 Polyarthritis 22 3.8 3.8 signal
171 Contraindicated Product Administered 126 3.8 3.8 signal
172 Feeling Drunk 31 3.8 3.8 signal
173 Diverticulum Intestinal 18 3.8 3.8 signal
174 Sickle Cell Anaemia With Crisis 65 3.7 3.7 signal
175 Scar 70 3.7 3.7 signal
176 Sensation Of Heaviness 16 3.7 3.7 signal
177 Intervertebral Disc Protrusion 89 3.7 3.7 signal
178 Umbilical Hernia 19 3.7 3.7 signal
179 Breath Sounds Abnormal 20 3.7 3.7 signal
180 Abdominal Discomfort 677 3.7 3.8 signal
181 Aneurysm 20 3.6 3.6 signal
182 Loss Of Personal Independence In Daily Activities 189 3.6 3.6 signal
183 Poor Quality Sleep 85 3.6 3.6 signal
184 Alanine Aminotransferase Increased 244 3.6 3.6 signal
185 Micturition Urgency 45 3.6 3.6 signal
186 Hair Disorder 33 3.6 3.6 signal
187 Uterine Leiomyoma 29 3.6 3.6 signal
188 Middle Insomnia 73 3.6 3.6 signal
189 Dyspareunia 18 3.6 3.6 signal
190 C-reactive Protein Increased 142 3.5 3.6 signal
191 Tooth Fracture 43 3.5 3.5 signal
192 Dental Caries 43 3.5 3.5 signal
193 Neck Pain 216 3.5 3.5 signal
194 Ventricular Extrasystoles 40 3.5 3.5 signal
195 Coronary Artery Disease 117 3.5 3.5 signal
196 Economic Problem 59 3.5 3.5 signal
197 Abdominal Tenderness 19 3.5 3.5 signal
198 Choking Sensation 21 3.5 3.5 signal
199 Endometriosis 18 3.4 3.4 signal
200 Pulse Absent 18 3.4 3.4 signal
201 Somnolence 758 3.4 3.5 signal
202 Anxiety 1,071 3.4 3.5 signal
203 Ligament Sprain 37 3.4 3.4 signal
204 Purulent Discharge 16 3.4 3.4 signal
205 Sleep Apnoea Syndrome 71 3.4 3.4 signal
206 Nonspecific Reaction 20 3.4 3.4 signal
207 Psychomotor Hyperactivity 61 3.3 3.3 signal
208 Dysuria 134 3.3 3.3 signal
209 Concussion 28 3.3 3.3 signal
210 Wrong Product Administered 24 3.3 3.3 signal
211 Body Height Decreased 39 3.3 3.3 signal
212 Therapeutic Response Unexpected 162 3.3 3.3 signal
213 Formication 25 3.3 3.3 signal
214 Product Label Issue 24 3.3 3.3 signal
215 Ovarian Cyst 36 3.3 3.3 signal
216 Glucose Tolerance Impaired 21 3.2 3.2 signal
217 Affective Disorder 28 3.2 3.2 signal
218 Atrial Septal Defect 30 3.2 3.2 signal
219 Menorrhagia 71 3.2 3.2 signal
220 Therapeutic Product Effect Delayed 16 3.2 3.2 signal
221 Dyslipidaemia 18 3.2 3.2 signal
222 Blood Albumin Decreased 28 3.2 3.2 signal
223 Expired Product Administered 117 3.2 3.2 signal
224 Gingivitis 19 3.2 3.2 signal
225 Peroneal Nerve Palsy 20 3.2 3.2 signal
226 Obesity 56 3.2 3.2 signal
227 Inflammation 180 3.2 3.2 signal
228 Rash Pruritic 189 3.2 3.2 signal
229 Hair Colour Changes 44 3.2 3.2 signal
230 Somnambulism 23 3.2 3.2 signal
231 Infective Pulmonary Exacerbation Of Cystic Fibrosis 19 3.1 3.1 signal
232 Hepatomegaly 34 3.1 3.1 signal
233 Hair Texture Abnormal 46 3.1 3.1 signal
234 Bursitis 41 3.1 3.1 signal
235 Vaginal Infection 16 3.1 3.1 signal
236 Hand Fracture 24 3.1 3.1 signal
237 Expired Drug Administered 17 3.1 3.1 signal
238 Vitamin D Deficiency 33 3.1 3.1 signal
239 Spinal Disorder 32 3.1 3.1 signal
240 Muscle Strain 29 3.0 3.1 signal
241 Renal Tubular Necrosis 33 3.0 3.1 signal
242 Carpal Tunnel Syndrome 47 3.0 3.0 signal
243 Arteriosclerosis Coronary Artery 22 3.0 3.0 signal
244 Restlessness 122 3.0 3.0 signal
245 Tooth Abscess 34 3.0 3.0 signal
246 Haemorrhoids 65 3.0 3.0 signal
247 Genital Haemorrhage 43 3.0 3.0 signal
248 Hypoaesthesia Oral 50 3.0 3.0 signal
249 Gastrooesophageal Reflux Disease 266 3.0 3.0 signal
250 Toothache 60 3.0 3.0 signal
251 End Stage Renal Disease 61 3.0 3.0 signal
252 Abasia 83 3.0 3.0 signal
253 Deformity 31 3.0 3.0 signal
254 Dysmenorrhoea 43 3.0 3.0 signal
255 Increased Upper Airway Secretion 17 3.0 3.0 signal
256 Peripheral Vascular Disorder 17 3.0 3.0 signal
257 Renal Cyst 26 3.0 3.0 signal
258 Skin Warm 19 3.0 3.0 signal
259 Upper Gastrointestinal Haemorrhage 55 3.0 3.0 signal
260 Musculoskeletal Pain 172 3.0 3.0 signal
261 Madarosis 38 2.9 3.0 signal
262 Musculoskeletal Chest Pain 50 2.9 2.9 signal
263 Osteoarthritis 137 2.9 2.9 signal
264 Hepatic Steatosis 60 2.9 2.9 signal
265 Gastric Ulcer Haemorrhage 18 2.9 2.9 signal
266 Drug Effect Decreased 176 2.9 2.9 signal
267 Musculoskeletal Stiffness 280 2.9 2.9 signal
268 Apnoea 25 2.9 2.9 signal
269 Abdominal Pain Upper 653 2.9 2.9 signal
270 Pain 1,955 2.9 3.1 signal
271 Bone Disorder 58 2.9 2.9 signal
272 Haematocrit Decreased 63 2.9 2.9 signal
273 Muscle Tightness 51 2.9 2.9 signal
274 Left Ventricular Dysfunction 21 2.9 2.9 signal
275 Pathological Fracture 16 2.9 2.9 signal
276 Dyspepsia 309 2.9 2.9 signal
277 Insomnia 840 2.9 2.9 signal
278 Skin Laceration 34 2.9 2.9 signal
279 Embedded Device 31 2.9 2.9 signal
280 Blood Cholesterol Increased 146 2.8 2.9 signal
281 Arthropod Bite 23 2.8 2.8 signal
282 Ear Discomfort 32 2.8 2.8 signal
283 Product Physical Issue 62 2.8 2.8 signal
284 Oesophagitis 34 2.8 2.8 signal
285 Blood Triglycerides Increased 55 2.8 2.8 signal
286 Crying 113 2.8 2.8 signal
287 Depression 707 2.8 2.9 signal
288 Chest Pain 574 2.8 2.9 signal
289 Visual Disturbance 18 2.8 2.8 signal
290 Brain Injury 31 2.8 2.8 signal
291 Nervousness 162 2.8 2.8 signal
292 Compression Fracture 16 2.8 2.8 signal
293 Cyst 38 2.8 2.8 signal
294 Streptococcal Infection 17 2.8 2.8 signal
295 Local Swelling 54 2.8 2.8 signal
296 Pharyngitis Streptococcal 33 2.8 2.8 signal
297 Product Use Complaint 47 2.8 2.8 signal
298 Lung Infiltration 27 2.8 2.8 signal
299 Hysterectomy 26 2.7 2.7 signal
300 Retching 64 2.7 2.7 signal
301 Gastrointestinal Haemorrhage 253 2.7 2.8 signal
302 Euphoric Mood 31 2.7 2.7 signal
303 Bronchiectasis 20 2.7 2.7 signal
304 Pregnancy With Contraceptive Device 27 2.7 2.7 signal
305 Ear Pain 58 2.7 2.7 signal
306 Product Taste Abnormal 40 2.7 2.7 signal
307 Foot Deformity 33 2.7 2.7 signal
308 Pharyngolaryngeal Pain 16 2.7 2.7 signal
309 Diplopia 77 2.7 2.7 signal
310 Lower Gastrointestinal Haemorrhage 22 2.7 2.7 signal
311 Lymphadenopathy 105 2.7 2.7 signal
312 Mental Disorder 129 2.7 2.7 signal
313 Head Discomfort 52 2.7 2.7 signal
314 Activated Partial Thromboplastin Time Prolonged 15 2.7 2.7 signal
315 Abnormal Dreams 82 2.7 2.7 signal
316 Paranoia 51 2.7 2.7 signal
317 Renal Injury 88 2.7 2.7 signal
318 Upper Respiratory Tract Infection 135 2.7 2.7 signal
319 Abdominal Pain Lower 74 2.6 2.7 signal
320 Facial Pain 26 2.6 2.6 signal
321 Impaired Driving Ability 33 2.6 2.6 signal
322 Arthritis 227 2.6 2.6 signal
323 Hypersomnia 82 2.6 2.6 signal
324 Stress 205 2.6 2.6 signal
325 Joint Dislocation 30 2.6 2.6 signal
326 Limb Discomfort 88 2.6 2.6 signal
327 Sinus Headache 17 2.6 2.6 signal
328 Type 2 Diabetes Mellitus 96 2.6 2.6 signal
329 General Physical Health Deterioration 326 2.6 2.6 signal
330 Back Pain 659 2.6 2.6 signal
331 Haematemesis 72 2.6 2.6 signal
332 Blood Pressure Diastolic Decreased 21 2.6 2.6 signal
333 Colitis Ischaemic 19 2.6 2.6 signal
334 Nerve Compression 26 2.6 2.6 signal
335 Renal Failure Chronic 22 2.6 2.6 signal
336 Procedural Pain 78 2.6 2.6 signal
337 Central Nervous System Lesion 39 2.6 2.6 signal
338 Chronic Kidney Disease 215 2.5 2.6 signal
339 Premature Labour 16 2.5 2.5 signal
340 Transient Ischaemic Attack 95 2.5 2.6 signal
341 Oedema Peripheral 342 2.5 2.6 signal
342 Sinus Bradycardia 27 2.5 2.5 signal
343 Pyelonephritis 24 2.5 2.5 signal
344 Migraine 264 2.5 2.5 signal
345 Choking 54 2.5 2.5 signal
346 Ventricular Septal Defect 16 2.5 2.5 signal
347 Sciatica 44 2.5 2.5 signal
348 Urinary Incontinence 82 2.5 2.5 signal
349 Feeling Abnormal 666 2.5 2.6 signal
350 Coagulopathy 46 2.5 2.5 signal
351 Headache 1,731 2.5 2.6 signal
352 Gingival Pain 22 2.5 2.5 signal
353 Meniscus Injury 17 2.5 2.5 signal
354 Bipolar Disorder 30 2.5 2.5 signal
355 Rib Fracture 56 2.5 2.5 signal
356 Sensory Loss 22 2.5 2.5 signal
357 Cold Sweat 48 2.5 2.5 signal
358 Hypercholesterolaemia 26 2.5 2.5 signal
359 Hemiparesis 46 2.4 2.5 signal
360 Therapy Non-responder 120 2.4 2.5 signal
361 Pulmonary Mass 40 2.4 2.4 signal
362 Heart Rate Irregular 61 2.4 2.4 signal
363 Hydronephrosis 20 2.4 2.4 signal
364 Nightmare 93 2.4 2.4 signal
365 Drug Intolerance 257 2.4 2.4 signal
366 Irritable Bowel Syndrome 57 2.4 2.4 signal
367 Electrocardiogram Abnormal 21 2.4 2.4 signal
368 Oral Discomfort 37 2.4 2.4 signal
369 Coeliac Disease 26 2.4 2.4 signal
370 Intentional Product Misuse 229 2.4 2.4 signal
371 Visual Field Defect 19 2.4 2.4 signal
372 Eye Movement Disorder 18 2.4 2.4 signal
373 Renal Failure Acute 113 2.4 2.4 signal
374 Joint Range Of Motion Decreased 35 2.4 2.4 signal
375 Hypoaesthesia 392 2.4 2.4 signal
376 Bladder Disorder 26 2.4 2.4 signal
377 Accident 31 2.4 2.4 signal
378 Joint Effusion 18 2.4 2.4 signal
379 Leukocytosis 47 2.4 2.4 signal
380 Refusal Of Treatment By Patient 17 2.4 2.4 signal
381 Muscle Twitching 60 2.4 2.4 signal
382 Gastrointestinal Disorder 229 2.4 2.4 signal
383 Infusion Related Reaction 171 2.3 2.4 signal
384 Tinnitus 119 2.3 2.4 signal
385 Dysphagia 244 2.3 2.4 signal
386 Abdominal Pain 599 2.3 2.4 signal
387 Mobility Decreased 184 2.3 2.3 signal
388 Pain In Extremity 757 2.3 2.4 signal
389 Inadequate Analgesia 22 2.3 2.3 signal
390 Rotator Cuff Syndrome 33 2.3 2.3 signal
391 Stevens-johnson Syndrome 57 2.3 2.3 signal
392 Renal Pain 27 2.3 2.3 signal
393 Mental Status Changes 71 2.3 2.3 signal
394 Convulsion 148 2.3 2.3 signal
395 Diabetes Mellitus Inadequate Control 45 2.3 2.3 signal
396 Decreased Appetite 588 2.3 2.3 signal
397 Cystitis 81 2.3 2.3 signal
398 Anger 86 2.3 2.3 signal
399 Optic Neuritis 23 2.3 2.3 signal
400 Decreased Activity 27 2.3 2.3 signal
401 Toxic Epidermal Necrolysis 38 2.3 2.3 signal
402 Impaired Work Ability 54 2.3 2.3 signal
403 Photophobia 47 2.3 2.3 signal
404 Sinus Congestion 34 2.3 2.3 signal
405 Hypokalaemia 115 2.3 2.3 signal
406 Back Injury 27 2.3 2.3 signal
407 Blood Alkaline Phosphatase Increased 62 2.3 2.3 signal
408 Therapeutic Product Effect Incomplete 176 2.3 2.3 signal
409 Ecchymosis 17 2.2 2.2 signal
410 Vitreous Floaters 24 2.2 2.2 signal
411 Dizziness 1,223 2.2 2.3 signal
412 Ankylosing Spondylitis 32 2.2 2.2 signal
413 Initial Insomnia 25 2.2 2.2 signal
414 Crohn's Disease 17 2.2 2.2 signal
415 Viral Infection 81 2.2 2.2 signal
416 Ataxia 29 2.2 2.2 signal
417 Impaired Gastric Emptying 31 2.2 2.2 signal
418 Swelling Face 158 2.2 2.2 signal
419 Nephrolithiasis 111 2.2 2.2 signal
420 Tooth Infection 32 2.2 2.2 signal
421 Blood Urine Present 46 2.2 2.2 signal
422 Drug Effect Less Than Expected 34 2.2 2.2 signal
423 Duodenal Ulcer 17 2.2 2.2 signal
424 Accidental Overdose 88 2.2 2.2 signal
425 Acute Respiratory Failure 46 2.2 2.2 signal
426 Splenomegaly 28 2.2 2.2 signal
427 Speech Disorder 125 2.2 2.2 signal
428 Quality Of Life Decreased 32 2.2 2.2 signal
429 Gastroenteritis Viral 43 2.2 2.2 signal
430 Pharyngeal Oedema 37 2.2 2.2 signal
431 Emphysema 24 2.2 2.2 signal
432 Product Use In Unapproved Indication 577 2.1 2.2 signal
433 Respiratory Rate Increased 21 2.1 2.1 signal
434 Joint Swelling 284 2.1 2.2 signal
435 Temperature Intolerance 24 2.1 2.1 signal
436 Coordination Abnormal 33 2.1 2.1 signal
437 Breast Pain 25 2.1 2.1 signal
438 Cellulitis 118 2.1 2.1 signal
439 Muscle Disorder 19 2.1 2.1 signal
440 Menstrual Disorder 19 2.1 2.1 signal
441 Vomiting 1,087 2.1 2.2 signal
442 Heart Rate Increased 229 2.1 2.1 signal
443 Nocturia 28 2.1 2.1 signal
444 Autoimmune Hepatitis 16 2.1 2.1 signal
445 Influenza Like Illness 191 2.1 2.1 signal
446 Osteoporosis 95 2.1 2.1 signal
447 Fibromyalgia 56 2.1 2.1 signal
448 Throat Irritation 103 2.1 2.1 signal
449 Road Traffic Accident 96 2.1 2.1 signal
450 Urine Output Decreased 20 2.1 2.1 signal
451 Nausea 1,797 2.1 2.2 signal
452 Panic Attack 83 2.1 2.1 signal
453 Weight Decreased 634 2.1 2.1 signal
454 Gastroenteritis 33 2.1 2.1 signal
455 Dysstasia 66 2.0 2.0 signal
456 Pulmonary Fibrosis 43 2.0 2.0 signal
457 Blood Potassium Decreased 67 2.0 2.0 signal
458 Neuralgia 54 2.0 2.0 signal
459 Irritability 134 2.0 2.0 signal
460 Multi-organ Failure 39 2.0 2.0 signal
461 Pain In Jaw 63 2.0 2.0 signal
462 Panic Reaction 16 2.0 2.0 signal
463 Anorexia 29 2.0 2.0 signal
464 Vitamin D Decreased 19 2.0 2.0 signal
465 Rheumatoid Arthritis 250 2.0 2.0 signal
466 Joint Stiffness 58 2.0 2.0 signal
467 Decubitus Ulcer 18 2.0 2.0 signal
468 Abnormal Behaviour 88 2.0 2.0 signal
469 Palpitations 258 2.0 2.0 signal
470 Night Sweats 71 2.0 2.0 signal
471 Abnormal Faeces 18 2.0 2.0 no signal
472 Gingival Bleeding 30 2.0 2.0 no signal
473 Tooth Disorder 49 2.0 2.0 no signal
474 Disorientation 87 2.0 2.0 no signal
475 Thinking Abnormal 41 2.0 2.0 no signal
476 Agitation 161 2.0 2.0 no signal
477 Oral Disorder 16 2.0 2.0 no signal
478 Sinus Disorder 43 2.0 2.0 no signal
479 Eye Swelling 80 2.0 2.0 no signal
480 Gait Disturbance 415 2.0 2.0 no signal
481 Emotional Disorder 67 2.0 2.0 no signal
482 Amnesia 141 2.0 2.0 no signal
483 Paraesthesia Oral 31 2.0 2.0 no signal
484 Peripheral Swelling 330 2.0 2.0 no signal
485 Dry Mouth 174 1.9 2.0 no signal
486 Paraesthesia 338 1.9 2.0 no signal
487 Arthralgia 888 1.9 2.0 no signal
488 Hypertension 454 1.9 2.0 no signal
489 Metastases To Bone 35 1.9 1.9 no signal
490 Blood Urea Increased 36 1.9 1.9 no signal
491 Drug Ineffective 2,813 1.9 2.1 no signal
492 Inflammatory Bowel Disease 21 1.9 1.9 no signal
493 Medical Device Complication 16 1.9 1.9 no signal
494 Parosmia 16 1.9 1.9 no signal
495 Faeces Discoloured 46 1.9 1.9 no signal
496 Troponin Increased 16 1.9 1.9 no signal
497 Sinus Tachycardia 30 1.9 1.9 no signal
498 Hypoxia 74 1.9 1.9 no signal
499 Blood Creatinine Increased 138 1.9 1.9 no signal
500 Rhinitis 17 1.9 1.9 no signal
501 Pulmonary Hypertension 44 1.9 1.9 no signal
502 Coronary Artery Occlusion 29 1.9 1.9 no signal
503 Skin Disorder 70 1.9 1.9 no signal
504 Body Temperature Increased 43 1.9 1.9 no signal
505 Mood Swings 67 1.9 1.9 no signal
506 Supraventricular Tachycardia 20 1.9 1.9 no signal
507 Vaginal Haemorrhage 89 1.9 1.9 no signal
508 Pollakiuria 87 1.9 1.9 no signal
509 Osteonecrosis Of Jaw 52 1.9 1.9 no signal
510 Blood Magnesium Decreased 18 1.9 1.9 no signal
511 Burning Sensation 146 1.9 1.9 no signal
512 Angina Pectoris 60 1.9 1.9 no signal
513 Thrombosis 167 1.9 1.9 no signal
514 Bronchitis 154 1.9 1.9 no signal
515 Ankle Fracture 32 1.9 1.9 no signal
516 Chills 242 1.9 1.9 no signal
517 Increased Tendency To Bruise 19 1.9 1.9 no signal
518 Head Injury 65 1.9 1.9 no signal
519 Bedridden 27 1.9 1.9 no signal
520 Muscle Spasms 377 1.9 1.9 no signal
521 Therapeutic Product Effect Decreased 91 1.9 1.9 no signal
522 Urticaria 341 1.9 1.9 no signal
523 Oral Pain 46 1.9 1.9 no signal
524 Dysarthria 77 1.9 1.9 no signal
525 Decreased Immune Responsiveness 20 1.9 1.9 no signal
526 Acute Coronary Syndrome 17 1.8 1.8 no signal
527 Discomfort 123 1.8 1.8 no signal
528 Vision Blurred 277 1.8 1.8 no signal
529 Prescribed Overdose 39 1.8 1.8 no signal
530 Sinusitis 207 1.8 1.8 no signal
531 Dehydration 268 1.8 1.8 no signal
532 Feeling Cold 56 1.8 1.8 no signal
533 Tachypnoea 27 1.8 1.8 no signal
534 Laceration 19 1.8 1.8 no signal
535 Drug Ineffective For Unapproved Indication 111 1.8 1.8 no signal
536 Frustration Tolerance Decreased 16 1.8 1.8 no signal
537 Pleural Effusion 121 1.8 1.8 no signal
538 Malnutrition 22 1.8 1.8 no signal
539 Bone Pain 116 1.8 1.8 no signal
540 Motor Dysfunction 20 1.8 1.8 no signal
541 Overdose 426 1.8 1.8 no signal
542 Metrorrhagia 34 1.8 1.8 no signal
543 Lethargy 113 1.8 1.8 no signal
544 Acidosis 15 1.8 1.8 no signal
545 Iron Deficiency Anaemia 18 1.8 1.8 no signal
546 Hypersensitivity 363 1.8 1.8 no signal
547 Mucosal Inflammation 51 1.8 1.8 no signal
548 Multiple Sclerosis Relapse 135 1.8 1.8 no signal
549 Upper-airway Cough Syndrome 16 1.8 1.8 no signal
550 Eye Disorder 64 1.8 1.8 no signal
551 Abdominal Distension 203 1.8 1.8 no signal
552 Constipation 422 1.8 1.8 no signal
553 Liver Function Test Abnormal 57 1.8 1.8 no signal
554 Foot Fracture 37 1.8 1.8 no signal
555 Presyncope 47 1.8 1.8 no signal
556 Libido Decreased 24 1.8 1.8 no signal
557 Vertigo 118 1.8 1.8 no signal
558 Suicidal Ideation 177 1.8 1.8 no signal
559 Sleep Disorder 135 1.7 1.8 no signal
560 Groin Pain 17 1.7 1.7 no signal
561 Throat Tightness 52 1.7 1.7 no signal
562 Uveitis 26 1.7 1.7 no signal
563 Disturbance In Attention 104 1.7 1.7 no signal
564 Renal Failure 257 1.7 1.8 no signal
565 Disability 38 1.7 1.7 no signal
566 Wrist Fracture 23 1.7 1.7 no signal
567 Increased Appetite 36 1.7 1.7 no signal
568 Contusion 184 1.7 1.7 no signal
569 Body Temperature Decreased 19 1.7 1.7 no signal
570 Seasonal Allergy 27 1.7 1.7 no signal
571 Device Dislocation 83 1.7 1.7 no signal
572 Urinary Tract Infection 325 1.7 1.7 no signal
573 Erythema 392 1.7 1.7 no signal
574 Hyperhidrosis 246 1.7 1.7 no signal
575 Spinal Compression Fracture 16 1.7 1.7 no signal
576 Pancreatitis 100 1.7 1.7 no signal
577 Pulmonary Congestion 25 1.7 1.7 no signal
578 Incontinence 20 1.7 1.7 no signal
579 Ventricular Fibrillation 21 1.7 1.7 no signal
580 Bacterial Infection 35 1.7 1.7 no signal
581 Balance Disorder 163 1.7 1.7 no signal
582 Diabetes Mellitus 144 1.7 1.7 no signal
583 Flushing 192 1.7 1.7 no signal
584 Spinal Pain 22 1.7 1.7 no signal
585 Impaired Quality Of Life 27 1.7 1.7 no signal
586 Feeling Hot 115 1.7 1.7 no signal
587 Tooth Loss 39 1.7 1.7 no signal
588 Unresponsive To Stimuli 48 1.7 1.7 no signal
589 Treatment Failure 153 1.7 1.7 no signal
590 Blood Sodium Decreased 35 1.7 1.7 no signal
591 Muscular Weakness 211 1.7 1.7 no signal
592 Rectal Haemorrhage 80 1.7 1.7 no signal
593 Multiple Sclerosis 89 1.7 1.7 no signal
594 Red Blood Cell Count Decreased 53 1.7 1.7 no signal
595 Respiratory Distress 51 1.7 1.7 no signal
596 Hyperglycaemia 67 1.7 1.7 no signal
597 Hallucination 138 1.7 1.7 no signal
598 Cyanosis 29 1.7 1.7 no signal
599 Mood Altered 50 1.7 1.7 no signal
600 Platelet Count Increased 24 1.7 1.7 no signal
601 Dysgeusia 137 1.7 1.7 no signal
602 Fatigue 1,417 1.7 1.7 no signal
603 Chest Discomfort 186 1.7 1.7 no signal
604 Acute Myocardial Infarction 54 1.7 1.7 no signal
605 Respiratory Tract Congestion 29 1.7 1.7 no signal
606 Pruritus Generalised 40 1.7 1.7 no signal
607 Brain Oedema 23 1.7 1.7 no signal
608 Metastases To Lung 21 1.6 1.7 no signal
609 White Blood Cell Count Increased 70 1.6 1.7 no signal
610 Tremor 302 1.6 1.7 no signal
611 Lip Swelling 60 1.6 1.6 no signal
612 Sensory Disturbance 29 1.6 1.6 no signal
613 Conjunctivitis 33 1.6 1.6 no signal
614 Hypotonia 18 1.6 1.6 no signal
615 Intentional Drug Misuse 38 1.6 1.6 no signal
616 Flatulence 101 1.6 1.6 no signal
617 Myositis 16 1.6 1.6 no signal
618 Aphasia 54 1.6 1.6 no signal
619 Product Use Issue 333 1.6 1.6 no signal
620 Hepatic Enzyme Increased 121 1.6 1.6 no signal
621 Tendon Rupture 22 1.6 1.6 no signal
622 Nasal Congestion 104 1.6 1.6 no signal
623 Aggression 89 1.6 1.6 no signal
624 Alopecia 349 1.6 1.6 no signal
625 Pyrexia 614 1.6 1.6 no signal
626 Urinary Retention 59 1.6 1.6 no signal
627 Blood Calcium Decreased 20 1.6 1.6 no signal
628 Oral Candidiasis 23 1.6 1.6 no signal
629 Tooth Extraction 22 1.6 1.6 no signal
630 Helicobacter Infection 18 1.6 1.6 no signal
631 Tubulointerstitial Nephritis 33 1.6 1.6 no signal
632 Poor Quality Product Administered 18 1.6 1.6 no signal
633 Neutrophil Count Increased 18 1.6 1.6 no signal
634 Haematuria 60 1.6 1.6 no signal
635 Neuropathy Peripheral 165 1.6 1.6 no signal
636 Product Quality Issue 235 1.6 1.6 no signal
637 Blood Pressure Increased 267 1.6 1.6 no signal
638 Peripheral Coldness 24 1.6 1.6 no signal
639 Hot Flush 131 1.6 1.6 no signal
640 Drug Toxicity 24 1.6 1.6 no signal
641 Diverticulitis 48 1.6 1.6 no signal
642 Movement Disorder 56 1.6 1.6 no signal
643 Ejection Fraction Decreased 27 1.6 1.6 no signal
644 Mental Impairment 42 1.6 1.6 no signal
645 Petechiae 18 1.6 1.6 no signal
646 Myalgia 294 1.6 1.6 no signal
647 Sedation 45 1.6 1.6 no signal
648 Dyskinesia 70 1.6 1.6 no signal
649 Haematochezia 95 1.6 1.6 no signal
650 Appendicitis 16 1.6 1.6 no signal
651 Hypokinesia 25 1.6 1.6 no signal
652 Personality Change 16 1.6 1.6 no signal
653 Eyelid Oedema 20 1.5 1.5 no signal
654 Generalised Oedema 21 1.5 1.5 no signal
655 Nerve Injury 19 1.5 1.5 no signal
656 Drug Administration Error 53 1.5 1.5 no signal
657 Blood Bilirubin Increased 46 1.5 1.5 no signal
658 No Therapeutic Response 21 1.5 1.5 no signal
659 Lymphocyte Count Decreased 30 1.5 1.5 no signal
660 Acute Respiratory Distress Syndrome 30 1.5 1.5 no signal
661 Swollen Tongue 53 1.5 1.5 no signal
662 Abscess 27 1.5 1.5 no signal
663 Muscle Spasticity 21 1.5 1.5 no signal
664 Acute Hepatic Failure 23 1.5 1.5 no signal
665 Depressed Mood 89 1.5 1.5 no signal
666 Thirst 30 1.5 1.5 no signal
667 Kidney Infection 33 1.5 1.5 no signal
668 Fall 559 1.5 1.5 no signal
669 Unevaluable Event 127 1.5 1.5 no signal
670 Impaired Healing 55 1.5 1.5 no signal
671 Dry Throat 17 1.5 1.5 no signal
672 Sluggishness 17 1.5 1.5 no signal
673 Oedema 90 1.5 1.5 no signal
674 Glaucoma 32 1.5 1.5 no signal
675 Skin Discolouration 76 1.5 1.5 no signal
676 Dyspnoea Exertional 62 1.5 1.5 no signal
677 Chronic Obstructive Pulmonary Disease 86 1.5 1.5 no signal
678 Renal Disorder 77 1.5 1.5 no signal
679 Confusional State 266 1.5 1.5 no signal
680 Injection Site Haematoma 24 1.5 1.5 no signal
681 Intentional Product Use Issue 144 1.5 1.5 no signal
682 Asthenia 612 1.5 1.5 no signal
683 Limb Injury 44 1.5 1.5 no signal
684 Inappropriate Schedule Of Drug Administration 117 1.5 1.5 no signal
685 Memory Impairment 223 1.5 1.5 no signal
686 Cognitive Disorder 75 1.5 1.5 no signal
687 Eye Pain 89 1.5 1.5 no signal
688 Oropharyngeal Pain 149 1.5 1.5 no signal
689 Nodule 21 1.5 1.5 no signal
690 Rash Papular 36 1.5 1.5 no signal
691 Tachycardia 142 1.4 1.5 no signal
692 Back Disorder 26 1.4 1.4 no signal
693 Fungal Infection 53 1.4 1.4 no signal
694 Psychotic Disorder 47 1.4 1.4 no signal
695 Cerebrovascular Accident 270 1.4 1.4 no signal
696 Hip Arthroplasty 24 1.4 1.4 no signal
697 Anaemia 300 1.4 1.4 no signal
698 Hallucination, Auditory 25 1.4 1.4 no signal
699 Eye Haemorrhage 21 1.4 1.4 no signal
700 Dyspnoea 886 1.4 1.4 no signal
701 Electrolyte Imbalance 18 1.4 1.4 no signal
702 Pericardial Effusion 36 1.4 1.4 no signal
703 Productive Cough 74 1.4 1.4 no signal
704 Gout 28 1.4 1.4 no signal
705 Wheezing 92 1.4 1.4 no signal
706 Weight Increased 345 1.4 1.4 no signal
707 Taste Disorder 31 1.4 1.4 no signal
708 Ileus 19 1.4 1.4 no signal
709 Injection Site Induration 20 1.4 1.4 no signal
710 Sexual Dysfunction 18 1.4 1.4 no signal
711 Hyponatraemia 86 1.4 1.4 no signal
712 Hallucination, Visual 32 1.4 1.4 no signal
713 Rash Generalised 40 1.4 1.4 no signal
714 Rash Macular 53 1.4 1.4 no signal
715 Epistaxis 114 1.4 1.4 no signal
716 Bone Loss 23 1.4 1.4 no signal
717 Hypomagnesaemia 21 1.4 1.4 no signal
718 Cerebral Infarction 37 1.4 1.4 no signal
719 Staphylococcal Infection 50 1.4 1.4 no signal
720 Swelling 141 1.4 1.4 no signal
721 Chromaturia 34 1.4 1.4 no signal
722 Extra Dose Administered 60 1.4 1.4 no signal
723 Haemoptysis 42 1.4 1.4 no signal
724 Rash 651 1.4 1.4 no signal
725 Respiratory Disorder 45 1.4 1.4 no signal
726 Hepatic Encephalopathy 14 1.4 1.4 no signal
727 Infection 216 1.4 1.4 no signal
728 Grand Mal Convulsion 14 1.4 1.4 no signal
729 Therapeutic Response Decreased 90 1.4 1.4 no signal
730 Cardiomyopathy 22 1.3 1.3 no signal
731 Squamous Cell Carcinoma 14 1.3 1.3 no signal
732 Metastases To Liver 26 1.3 1.3 no signal
733 Hypothyroidism 47 1.3 1.3 no signal
734 Loss Of Consciousness 189 1.3 1.3 no signal
735 Myocardial Infarction 259 1.3 1.3 no signal
736 Rash Erythematous 69 1.3 1.3 no signal
737 Encephalopathy 36 1.3 1.3 no signal
738 Rhinorrhoea 94 1.3 1.3 no signal
739 Hepatic Failure 44 1.3 1.3 no signal
740 Asthma 163 1.3 1.3 no signal
741 Suicide Attempt 88 1.3 1.3 no signal
742 Diarrhoea 931 1.3 1.3 no signal
743 Heart Rate Decreased 51 1.3 1.3 no signal
744 Bacteraemia 17 1.3 1.3 no signal
745 Device Issue 126 1.3 1.3 no signal
746 Blood Iron Decreased 17 1.3 1.3 no signal
747 Candida Infection 24 1.3 1.3 no signal
748 Visual Acuity Reduced 48 1.3 1.3 no signal
749 Cardiac Failure Congestive 116 1.3 1.3 no signal
750 Pallor 39 1.3 1.3 no signal
751 Malaise 627 1.3 1.3 no signal
752 Blindness 58 1.3 1.3 no signal
753 Blindness Unilateral 20 1.3 1.3 no signal
754 Anaphylactic Reaction 78 1.3 1.3 no signal
755 Cough 396 1.3 1.3 no signal
756 Blister 79 1.3 1.3 no signal
757 Infusion Site Pain 18 1.3 1.3 no signal
758 Dermatitis Contact 16 1.3 1.3 no signal
759 Blood Thyroid Stimulating Hormone Increased 13 1.3 1.3 no signal
760 Hepatitis 36 1.3 1.3 no signal
761 Nervous System Disorder 44 1.3 1.3 no signal
762 Localised Infection 34 1.3 1.3 no signal
763 Pharmaceutical Product Complaint 37 1.3 1.3 no signal
764 Spinal Fracture 28 1.3 1.3 no signal
765 Influenza 157 1.3 1.3 no signal
766 Hernia 27 1.3 1.3 no signal
767 Drug Administered At Inappropriate Site 15 1.3 1.3 no signal
768 Incorrect Drug Administration Duration 40 1.3 1.3 no signal
769 Product Packaging Issue 13 1.3 1.3 no signal
770 Photosensitivity Reaction 23 1.3 1.3 no signal
771 Bronchospasm 20 1.3 1.3 no signal
772 Vaginal Discharge 14 1.3 1.3 no signal
773 Herpes Zoster 80 1.3 1.3 no signal
774 Adverse Event 128 1.3 1.3 no signal
775 Diarrhoea Haemorrhagic 13 1.3 1.3 no signal
776 Pneumothorax 22 1.3 1.3 no signal
777 Dysphonia 81 1.3 1.3 no signal
778 Aspiration 15 1.3 1.3 no signal
779 Wrong Technique In Drug Usage Process 51 1.3 1.3 no signal
780 Intentional Overdose 88 1.3 1.3 no signal
781 Haemoglobin Decreased 142 1.3 1.3 no signal
782 Mouth Ulceration 29 1.2 1.2 no signal
783 Skin Fissures 26 1.2 1.2 no signal
784 Apathy 20 1.2 1.2 no signal
785 Vasculitis 16 1.2 1.2 no signal
786 Syncope 137 1.2 1.2 no signal
787 Incorrect Dose Administered 307 1.2 1.2 no signal
788 Fluid Overload 20 1.2 1.2 no signal
789 Dizziness Postural 13 1.2 1.2 no signal
790 Acute Kidney Injury 205 1.2 1.2 no signal
791 Pancreatitis Acute 30 1.2 1.2 no signal
792 Glossodynia 30 1.2 1.2 no signal
793 Knee Operation 13 1.2 1.2 no signal
794 Underdose 97 1.2 1.2 no signal
795 Mydriasis 17 1.2 1.2 no signal
796 Laboratory Test Abnormal 39 1.2 1.2 no signal
797 Cataract 78 1.2 1.2 no signal
798 Melaena 29 1.2 1.2 no signal
799 Liver Function Test Increased 28 1.2 1.2 no signal
800 Condition Aggravated 396 1.2 1.2 no signal
801 Internal Haemorrhage 15 1.2 1.2 no signal
802 Myocardial Ischaemia 15 1.2 1.2 no signal
803 Dermatitis 27 1.2 1.2 no signal
804 Dry Eye 63 1.2 1.2 no signal
805 Nasopharyngitis 240 1.2 1.2 no signal
806 Hand Deformity 17 1.2 1.2 no signal
807 Post Procedural Complication 25 1.2 1.2 no signal
808 Gait Inability 43 1.2 1.2 no signal
809 Sleep Disorder Due To A General Medical Condition 21 1.2 1.2 no signal
810 Thyroid Disorder 20 1.2 1.2 no signal
811 Jaundice 35 1.2 1.2 no signal
812 Adverse Drug Reaction 116 1.2 1.2 no signal
813 Pneumonitis 35 1.2 1.2 no signal
814 Blood Potassium Increased 21 1.2 1.2 no signal
815 Lung Disorder 63 1.2 1.2 no signal
816 Mass 18 1.2 1.2 no signal
817 Intestinal Obstruction 48 1.2 1.2 no signal
818 Menstruation Irregular 34 1.2 1.2 no signal
819 Withdrawal Syndrome 54 1.2 1.2 no signal
820 Eyelid Ptosis 13 1.2 1.2 no signal
821 Eye Inflammation 12 1.2 1.2 no signal
822 Ventricular Tachycardia 21 1.1 1.1 no signal
823 Multiple Fractures 21 1.1 1.1 no signal
824 Eructation 24 1.1 1.1 no signal
825 Pharyngeal Swelling 12 1.1 1.1 no signal
826 Device Failure 19 1.1 1.1 no signal
827 Diabetic Ketoacidosis 30 1.1 1.1 no signal
828 Upper Limb Fracture 25 1.1 1.1 no signal
829 Injection Site Mass 46 1.1 1.1 no signal
830 Hyperthyroidism 18 1.1 1.1 no signal
831 Pneumonia Aspiration 31 1.1 1.1 no signal
832 Arrhythmia 59 1.1 1.1 no signal
833 Lacrimation Increased 37 1.1 1.1 no signal
834 Complication Of Device Removal 21 1.1 1.1 no signal
835 Injection Site Urticaria 30 1.1 1.1 no signal
836 Oxygen Saturation Decreased 69 1.1 1.1 no signal
837 Cardiac Disorder 115 1.1 1.1 no signal
838 Small Intestinal Obstruction 15 1.1 1.1 no signal
839 Mania 20 1.1 1.1 no signal
840 Skin Lesion 33 1.1 1.1 no signal
841 Breast Cancer Metastatic 13 1.1 1.1 no signal
842 Blood Pressure Abnormal 24 1.1 1.1 no signal
843 Ageusia 30 1.1 1.1 no signal
844 Brain Neoplasm 11 1.1 1.1 no signal
845 Haemorrhage 125 1.1 1.1 no signal
846 Dialysis 17 1.1 1.1 no signal
847 Hunger 16 1.1 1.1 no signal
848 Drug Exposure During Pregnancy 41 1.1 1.1 no signal
849 Paralysis 17 1.1 1.1 no signal
850 Injection Site Erythema 146 1.1 1.1 no signal
851 Injection Site Reaction 81 1.1 1.1 no signal
852 Respiratory Failure 86 1.1 1.1 no signal
853 Angioedema 52 1.1 1.1 no signal
854 Subarachnoid Haemorrhage 12 1.1 1.1 no signal
855 Nephropathy 11 1.1 1.1 no signal
856 Abortion Spontaneous 47 1.1 1.1 no signal
857 Device Related Infection 18 1.1 1.1 no signal
858 Skin Infection 13 1.1 1.1 no signal
859 Pruritus 440 1.1 1.1 no signal
860 Fracture 22 1.1 1.1 no signal
861 Product Odour Abnormal 12 1.0 1.0 no signal
862 Weight Fluctuation 12 1.0 1.0 no signal
863 Sepsis 128 1.0 1.0 no signal
864 Scab 13 1.0 1.0 no signal
865 Colon Cancer 17 1.0 1.0 no signal
866 Application Site Pain 25 1.0 1.0 no signal
867 Secretion Discharge 14 1.0 1.0 no signal
868 Haemorrhage Intracranial 17 1.0 1.0 no signal
869 Visual Impairment 139 1.0 1.0 no signal
870 Injection Site Discolouration 14 1.0 1.0 no signal
871 Hepatotoxicity 25 1.0 1.0 no signal
872 Sneezing 25 1.0 1.0 no signal
873 Injection Site Bruising 88 1.0 1.0 no signal
874 Proteinuria 21 1.0 1.0 no signal
875 Muscle Atrophy 14 1.0 1.0 no signal
876 Blood Count Abnormal 17 1.0 1.0 no signal
877 Bone Density Decreased 35 1.0 1.0 no signal
878 Ill-defined Disorder 67 1.0 1.0 no signal
879 Lower Limb Fracture 21 1.0 1.0 no signal
880 Ocular Hyperaemia 51 1.0 1.0 no signal
881 Stomatitis 66 1.0 1.0 no signal
882 Ascites 32 1.0 1.0 no signal
883 White Blood Cell Count Decreased 118 1.0 1.0 no signal
884 Immunodeficiency 16 1.0 1.0 no signal
885 Drug Dose Omission 182 1.0 1.0 no signal
886 Prostatic Specific Antigen Increased 15 1.0 1.0 no signal
887 Drug Withdrawal Syndrome 96 1.0 1.0 no signal
888 Medication Error 60 1.0 1.0 no signal
889 Pericarditis 18 1.0 1.0 no signal
890 Wound 30 1.0 1.0 no signal
891 Respiratory Tract Infection 28 1.0 1.0 no signal
892 Surgery 62 1.0 1.0 no signal
893 Disease Recurrence 51 1.0 1.0 no signal
894 Intestinal Perforation 12 1.0 1.0 no signal
895 Immune System Disorder 14 1.0 1.0 no signal
896 Femur Fracture 33 1.0 1.0 no signal
897 Disseminated Intravascular Coagulation 15 1.0 1.0 no signal
898 Status Epilepticus 12 1.0 1.0 no signal
899 Leukaemia 10 1.0 1.0 no signal
900 Product Substitution Issue 61 1.0 1.0 no signal
901 Sputum Discoloured 10 1.0 1.0 no signal
902 Pulmonary Oedema 47 0.9 0.9 no signal
903 Erectile Dysfunction 27 0.9 0.9 no signal
904 Atrial Fibrillation 102 0.9 0.9 no signal
905 Application Site Irritation 13 0.9 0.9 no signal
906 Autoimmune Disorder 10 0.9 0.9 no signal
907 Malignant Melanoma 14 0.9 0.9 no signal
908 International Normalised Ratio Increased 30 0.9 0.9 no signal
909 Neoplasm 12 0.9 0.9 no signal
910 Generalised Tonic-clonic Seizure 17 0.9 0.9 no signal
911 Liver Disorder 46 0.9 0.9 no signal
912 Liver Injury 25 0.9 0.9 no signal
913 Delusion 16 0.9 0.9 no signal
914 Oral Herpes 20 0.9 0.9 no signal
915 Blood Glucose Increased 194 0.9 0.9 no signal
916 Complication Of Device Insertion 19 0.9 0.9 no signal
917 Caesarean Section 12 0.9 0.9 no signal
918 Cardiovascular Disorder 26 0.9 0.9 no signal
919 Laryngitis 11 0.9 0.9 no signal
920 Pneumonia 326 0.9 0.9 no signal
921 Drug Interaction 160 0.9 0.9 no signal
922 Knee Arthroplasty 21 0.9 0.9 no signal
923 Ischaemic Stroke 18 0.9 0.9 no signal
924 Hypocalcaemia 19 0.9 0.9 no signal
925 Hypotension 201 0.9 0.9 no signal
926 Adrenal Insufficiency 12 0.9 0.9 no signal
927 Product Administration Error 20 0.9 0.9 no signal
928 Product Complaint 25 0.9 0.9 no signal
929 Premature Delivery 16 0.9 0.9 no signal
930 Therapy Cessation 51 0.9 0.9 no signal
931 Bradycardia 53 0.9 0.9 no signal
932 Blood Pressure Fluctuation 24 0.9 0.9 no signal
933 Product Dose Omission 66 0.9 0.9 no signal
934 Glycosylated Haemoglobin Increased 25 0.9 0.9 no signal
935 Glomerular Filtration Rate Decreased 12 0.9 0.9 no signal
936 Schizophrenia 12 0.9 0.9 no signal
937 Obstructive Airways Disorder 11 0.9 0.9 no signal
938 Seizure 113 0.9 0.9 no signal
939 Complication Associated With Device 13 0.9 0.9 no signal
940 Blood Pressure Decreased 65 0.9 0.9 no signal
941 Retinal Detachment 9 0.9 0.9 no signal
942 Treatment Noncompliance 53 0.9 0.9 no signal
943 Erythema Multiforme 9 0.9 0.9 no signal
944 Shock 22 0.9 0.9 no signal
945 Injection Site Swelling 73 0.9 0.9 no signal
946 Hypoacusis 41 0.9 0.9 no signal
947 Intentional Dose Omission 26 0.9 0.9 no signal
948 Off Label Use 822 0.9 0.9 no signal
949 Face Oedema 16 0.9 0.9 no signal
950 Full Blood Count Decreased 19 0.9 0.9 no signal
951 Drug-induced Liver Injury 29 0.9 0.9 no signal
952 Incorrect Product Administration Duration 19 0.8 0.8 no signal
953 Renal Impairment 78 0.8 0.8 no signal
954 Injection Site Pruritus 62 0.8 0.8 no signal
955 Pain Of Skin 25 0.8 0.8 no signal
956 Ocular Discomfort 10 0.8 0.8 no signal
957 Metabolic Acidosis 29 0.8 0.8 no signal
958 Drug Dispensing Error 14 0.8 0.8 no signal
959 Cardio-respiratory Arrest 38 0.8 0.8 no signal
960 Skin Haemorrhage 13 0.8 0.8 no signal
961 Intentional Self-injury 18 0.8 0.8 no signal
962 Eye Infection 10 0.8 0.8 no signal
963 Brain Fog 13 0.8 0.8 no signal
964 Hypothermia 9 0.8 0.8 no signal
965 Injection Site Extravasation 11 0.8 0.8 no signal
966 Eye Irritation 49 0.8 0.8 no signal
967 Blood Lactate Dehydrogenase Increased 14 0.8 0.8 no signal
968 Injection Site Pain 266 0.8 0.8 no signal
969 Colitis 33 0.8 0.8 no signal
970 Dry Skin 115 0.8 0.8 no signal
971 Hyperbilirubinaemia 9 0.8 0.8 no signal
972 Dystonia 17 0.8 0.8 no signal
973 Platelet Count Decreased 93 0.8 0.8 no signal
974 Poor Venous Access 9 0.8 0.8 no signal
975 Delirium 30 0.8 0.8 no signal
976 Neutrophil Count Decreased 35 0.8 0.8 no signal
977 Metastases To Central Nervous System 11 0.8 0.8 no signal
978 Injection Site Haemorrhage 68 0.8 0.8 no signal
979 Injection Site Rash 26 0.8 0.8 no signal
980 Prescribed Underdose 17 0.8 0.8 no signal
981 Eye Pruritus 28 0.8 0.8 no signal
982 Fluid Retention 43 0.8 0.8 no signal
983 Haematoma 22 0.8 0.8 no signal
984 Osteonecrosis 28 0.8 0.8 no signal
985 Skin Exfoliation 69 0.8 0.8 no signal
986 Therapy Change 8 0.8 0.8 no signal
987 Premature Baby 25 0.8 0.7 no signal
988 Lung Infection 13 0.7 0.7 no signal
989 Leukopenia 41 0.7 0.7 no signal
990 Cardiac Arrest 68 0.7 0.7 no signal
991 Product Adhesion Issue 29 0.7 0.7 no signal
992 Therapeutic Response Shortened 26 0.7 0.7 no signal
993 Acne 62 0.7 0.7 no signal
994 Gamma-glutamyltransferase Increased 18 0.7 0.7 no signal
995 Septic Shock 35 0.7 0.7 no signal
996 Blood Glucose Decreased 39 0.7 0.7 no signal
997 Insurance Issue 12 0.7 0.7 no signal
998 Hepatic Cirrhosis 15 0.7 0.7 no signal
999 Salivary Hypersecretion 8 0.7 0.7 no signal
1000 Application Site Erythema 21 0.7 0.7 no signal
1001 Inappropriate Antidiuretic Hormone Secretion 8 0.7 0.7 no signal
1002 Hypoglycaemia 38 0.7 0.7 no signal
1003 Product Dose Omission In Error 21 0.7 0.7 no signal
1004 Anaphylactic Shock 20 0.7 0.7 no signal
1005 Psoriasis 102 0.7 0.7 no signal
1006 Amenorrhoea 13 0.7 0.7 no signal
1007 Scratch 8 0.7 0.7 no signal
1008 Tardive Dyskinesia 22 0.7 0.7 no signal
1009 Wrong Technique In Product Usage Process 155 0.7 0.7 no signal
1010 Rash Maculo-papular 17 0.7 0.7 no signal
1011 Transaminases Increased 17 0.7 0.7 no signal
1012 Hereditary Angioedema 8 0.7 0.7 no signal
1013 Transfusion 8 0.7 0.7 no signal
1014 Depressed Level Of Consciousness 30 0.7 0.7 no signal
1015 Urosepsis 7 0.7 0.7 no signal
1016 Full Blood Count Abnormal 8 0.7 0.7 no signal
1017 Covid-19 Pneumonia 9 0.7 0.7 no signal
1018 Neuroleptic Malignant Syndrome 9 0.7 0.7 no signal
1019 Ovarian Cancer 7 0.7 0.7 no signal
1020 Cerebral Haemorrhage 27 0.7 0.7 no signal
1021 Thrombocytopenia 84 0.7 0.7 no signal
1022 Drug Dependence 122 0.7 0.7 no signal
1023 Sars-cov-2 Test Positive 10 0.7 0.7 no signal
1024 Spinal Operation 9 0.7 0.7 no signal
1025 Pregnancy 15 0.7 0.7 no signal
1026 Device Defective 12 0.7 0.7 no signal
1027 Clostridium Difficile Infection 16 0.7 0.7 no signal
1028 Illness 74 0.7 0.7 no signal
1029 Wound Infection 8 0.7 0.7 no signal
1030 Pancytopenia 41 0.7 0.7 no signal
1031 Coma 35 0.7 0.7 no signal
1032 Application Site Rash 10 0.7 0.7 no signal
1033 Affect Lability 7 0.7 0.7 no signal
1034 Dermatitis Allergic 9 0.7 0.7 no signal
1035 Accidental Exposure To Product 72 0.7 0.7 no signal
1036 Dementia 20 0.7 0.7 no signal
1037 Hypertensive Crisis 8 0.6 0.6 no signal
1038 Hyperkalaemia 25 0.6 0.6 no signal
1039 Fistula 8 0.6 0.6 no signal
1040 Blood Glucose Abnormal 13 0.6 0.6 no signal
1041 Intraocular Pressure Increased 9 0.6 0.6 no signal
1042 Covid-19 124 0.6 0.6 no signal
1043 Incorrect Route Of Drug Administration 25 0.6 0.6 no signal
1044 Anosmia 10 0.6 0.6 no signal
1045 Device Breakage 27 0.6 0.6 no signal
1046 Eye Discharge 7 0.6 0.6 no signal
1047 Folliculitis 7 0.6 0.6 no signal
1048 Menstruation Delayed 7 0.6 0.6 no signal
1049 Drug Prescribing Error 13 0.6 0.6 no signal
1050 Febrile Neutropenia 44 0.6 0.6 no signal
1051 Epilepsy 20 0.6 0.6 no signal
1052 Incorrect Route Of Product Administration 11 0.6 0.6 no signal
1053 Hip Fracture 21 0.6 0.6 no signal
1054 Colitis Ulcerative 29 0.6 0.6 no signal
1055 Skin Cancer 14 0.6 0.6 no signal
1056 Malignant Neoplasm Progression 66 0.6 0.6 no signal
1057 Lymphoma 10 0.6 0.6 no signal
1058 Aphonia 9 0.6 0.6 no signal
1059 Blood Test Abnormal 9 0.6 0.6 no signal
1060 Pulmonary Thrombosis 7 0.6 0.6 no signal
1061 Device Malfunction 43 0.6 0.6 no signal
1062 Electrocardiogram Qt Prolonged 23 0.6 0.6 no signal
1063 Maternal Exposure During Pregnancy 56 0.6 0.6 no signal
1064 Injection Site Irritation 8 0.6 0.6 no signal
1065 Neoplasm Progression 22 0.6 0.6 no signal
1066 Myocarditis 7 0.6 0.6 no signal
1067 Lower Respiratory Tract Infection 28 0.6 0.6 no signal
1068 Product Dose Omission Issue 173 0.6 0.5 no signal
1069 Device Difficult To Use 40 0.5 0.5 no signal
1070 Drug Level Increased 10 0.5 0.5 no signal
1071 Post Procedural Haemorrhage 7 0.5 0.5 no signal
1072 Extrapyramidal Disorder 15 0.5 0.5 no signal
1073 Neoplasm Malignant 39 0.5 0.5 no signal
1074 Circulatory Collapse 10 0.5 0.5 no signal
1075 Injection Site Warmth 12 0.5 0.5 no signal
1076 Injection Site Discomfort 6 0.5 0.5 no signal
1077 Rhabdomyolysis 24 0.5 0.5 no signal
1078 Eczema 29 0.5 0.5 no signal
1079 Skeletal Injury 6 0.5 0.5 no signal
1080 Hepatitis C 7 0.5 0.5 no signal
1081 Application Site Pruritus 13 0.5 0.5 no signal
1082 Respiratory Depression 7 0.5 0.5 no signal
1083 Exposure During Pregnancy 35 0.5 0.5 no signal
1084 Skin Burning Sensation 40 0.5 0.5 no signal
1085 Lactic Acidosis 18 0.5 0.5 no signal
1086 Subdural Haematoma 8 0.5 0.5 no signal
1087 Altered State Of Consciousness 12 0.5 0.5 no signal
1088 Product Dispensing Error 12 0.5 0.5 no signal
1089 Product Packaging Quantity Issue 6 0.5 0.5 no signal
1090 Product Prescribing Error 13 0.5 0.5 no signal
1091 Injection Site Nodule 6 0.5 0.5 no signal
1092 Skin Irritation 25 0.5 0.5 no signal
1093 Disease Progression 64 0.5 0.5 no signal
1094 Hepatic Function Abnormal 20 0.5 0.5 no signal
1095 Respiratory Arrest 15 0.5 0.5 no signal
1096 Systemic Lupus Erythematosus 19 0.5 0.5 no signal
1097 Rebound Effect 6 0.5 0.5 no signal
1098 Breast Cancer Female 14 0.5 0.5 no signal
1099 Frequent Bowel Movements 14 0.5 0.5 no signal
1100 Device Use Issue 9 0.5 0.5 no signal
1101 Palmar-plantar Erythrodysaesthesia Syndrome 12 0.5 0.5 no signal
1102 Parkinsonism 5 0.5 0.5 no signal
1103 Hospice Care 5 0.5 0.5 no signal
1104 Muscle Rigidity 6 0.5 0.5 no signal
1105 Device Use Error 17 0.5 0.5 no signal
1106 Skin Reaction 7 0.5 0.5 no signal
1107 Cardiogenic Shock 7 0.4 0.4 no signal
1108 Peritonitis 10 0.4 0.4 no signal
1109 Inappropriate Schedule Of Product Administration 85 0.4 0.4 no signal
1110 No Adverse Event 85 0.4 0.4 no signal
1111 Drug Abuse 40 0.4 0.4 no signal
1112 Unintended Pregnancy 5 0.4 0.4 no signal
1113 Cholestasis 9 0.4 0.4 no signal
1114 Syringe Issue 8 0.4 0.4 no signal
1115 Blood Creatine Phosphokinase Increased 13 0.4 0.4 no signal
1116 Bone Marrow Failure 9 0.4 0.4 no signal
1117 Akathisia 6 0.4 0.4 no signal
1118 Therapy Interrupted 30 0.4 0.4 no signal
1119 Neutropenia 58 0.4 0.4 no signal
1120 Posterior Reversible Encephalopathy Syndrome 4 0.4 0.4 no signal
1121 Myoclonus 5 0.4 0.4 no signal
1122 Device Deployment Issue 5 0.4 0.4 no signal
1123 Thyroid Cancer 5 0.4 0.4 no signal
1124 Lung Neoplasm Malignant 17 0.4 0.4 no signal
1125 Meningioma 6 0.4 0.4 no signal
1126 Poisoning 5 0.4 0.4 no signal
1127 Foetal Exposure During Pregnancy 32 0.4 0.4 no signal
1128 Hospitalisation 60 0.4 0.4 no signal
1129 Breast Cancer 37 0.4 0.4 no signal
1130 Circumstance Or Information Capable Of Leading To Medication Error 13 0.4 0.4 no signal
1131 Product Preparation Error 8 0.3 0.3 no signal
1132 Acute Myeloid Leukaemia 6 0.3 0.3 no signal
1133 Device Expulsion 25 0.3 0.3 no signal
1134 Agranulocytosis 7 0.3 0.3 no signal
1135 Incorrect Product Storage 5 0.3 0.3 no signal
1136 Sudden Death 4 0.3 0.3 no signal
1137 Hepatic Cancer 9 0.3 0.3 no signal
1138 Blood Glucose Fluctuation 4 0.3 0.3 no signal
1139 Dependence 20 0.3 0.3 no signal
1140 Plasma Cell Myeloma 14 0.3 0.3 no signal
1141 Product Availability Issue 8 0.3 0.3 no signal
1142 Cardiac Failure 28 0.3 0.3 no signal
1143 Neurotoxicity 6 0.3 0.3 no signal
1144 Eosinophilia 6 0.3 0.3 no signal
1145 Polyneuropathy 4 0.3 0.3 no signal
1146 Macular Degeneration 4 0.3 0.3 no signal
1147 Poisoning Deliberate 3 0.3 0.3 no signal
1148 Completed Suicide 27 0.3 0.3 no signal
1149 Abortion Induced 3 0.3 0.3 no signal
1150 Serotonin Syndrome 6 0.3 0.3 no signal
1151 Gastric Cancer 8 0.3 0.3 no signal
1152 Tuberculosis 4 0.3 0.3 no signal
1153 Prostate Cancer 25 0.3 0.3 no signal
1154 Death 260 0.3 0.3 no signal
1155 Toxicity To Various Agents 50 0.3 0.3 no signal
1156 Drug Level Decreased 3 0.3 0.3 no signal
1157 Gynaecomastia 9 0.3 0.3 no signal
1158 Device Leakage 12 0.3 0.3 no signal
1159 Myelodysplastic Syndrome 4 0.3 0.3 no signal
1160 Product Storage Error 22 0.2 0.2 no signal
1161 Pancreatic Carcinoma 7 0.2 0.2 no signal
1162 Abnormal Weight Gain 3 0.2 0.2 no signal
1163 Dermatitis Atopic 12 0.2 0.2 no signal
1164 Incorrect Dose Administered By Device 6 0.2 0.2 no signal
1165 Product Administered At Inappropriate Site 4 0.2 0.2 no signal
1166 Injury Associated With Device 4 0.2 0.2 no signal
1167 Drug Reaction With Eosinophilia And Systemic Symptoms 5 0.2 0.2 no signal
1168 Exposure Via Skin Contact 4 0.2 0.2 no signal
1169 Needle Issue 5 0.2 0.2 no signal
1170 Device Delivery System Issue 3 0.1 0.1 no signal
1171 Oesophageal Carcinoma 3 0.1 0.1 no signal
1172 Wrong Technique In Device Usage Process 4 0.1 0.1 no signal
1173 Bladder Cancer 5 0.1 0.1 no signal
1174 Drug Dose Omission By Device 6 0.1 0.1 no signal
1175 Colorectal Cancer 3 0.1 0.1 no signal