Reaction

Functional Gastrointestinal Disorder reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,421 reports · 157 co-occurring drugs

As of the last recalculation, Functional Gastrointestinal Disorder appears in 3,421 FAERS reports alongside 157 co-occurring drug terms. The strongest observed disproportionality signal is DICLOFENAC POTASSIUM, FILM COATED (PRR 65.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diclofenac Potassium, Film Coated	88	65.3	66.0
Diclofenac Potassium Tablets	88	65.2	65.9
Diclofenac Potassium	88	50.8	51.2
Ibuprofen And Diphenhydramine Citrate	77	20.6	20.6
Micafungin Sodium	21	15.2	15.2
Tramadol Hydrochloride	88	14.6	14.6
Trimethoprim	27	14.0	14.1
Basiliximab	22	11.4	11.5
Naproxen Sodium Tablet, Coated	22	9.9	10.0
Naproxen Sodium, Coated Tablets	22	9.9	10.0
Naproxen Sodium 220Mg	22	9.9	9.9
Chlorhexidine Gluconate	14	9.4	9.4
Ascorbic Acid	34	9.0	9.0
Diclofenac	119	8.7	8.7
Dalfampridine	97	8.4	8.4
Teriflunomide	61	8.3	8.3
Bisacodyl	19	8.3	8.3
Cyclobenzaprine Hydrochloride	12	8.1	8.2
Naproxen	102	8.1	8.1
Bisacodyl Suppositories	17	8.0	8.0
Infliximab-Dyyb	38	8.0	8.0
Biscodyl	17	8.0	8.0
Rifaximin	27	7.9	7.9
Mercaptopurine	22	7.8	7.8
Cholestyramine	15	7.6	7.6
Leflunomide	125	7.5	7.5
Linaclotide	32	7.4	7.4
Hydroxychloroquine Sulfate	106	7.3	7.3
Octreotide Acetate	35	7.0	7.0
Nicotine Polacrilex Mini	17	6.9	6.9
Nicotine Polarilex	17	6.9	6.9
Vitamin C	99	6.7	6.7
Calcium Gluconate	13	6.6	6.6
Lactulose	41	6.6	6.6
Diclofenac Sodium 1%	37	6.4	6.4
Diclofenac Sodium Topical	37	6.4	6.4
Diclofenac Sodium Topical Gel, 1%	37	6.3	6.4
Methylprednisolone Acetate	8	6.1	6.1
Mometasone	18	6.0	6.0
Voriconazole Injection	21	5.9	5.9
Mycophenilic Acid	20	5.9	5.9
Diclofenac Sodium	139	5.8	5.8
Hydroxychloroquine	70	5.8	5.8
Erythromycin	17	5.5	5.5
Naproxen Sodium	126	5.5	5.5
Cortisone Acetate	11	5.4	5.4
Midazolam	22	5.3	5.3
Hydrocortisone Acetate	62	5.3	5.3
Oxycodone And Acetaminophen	20	5.2	5.2
Midazolam Hydrochloride	23	5.2	5.2
Lubiprostone	8	5.2	5.2
Ibuprofen Capsule	153	4.8	4.8
Ibuprofen Tablet, Film Coated	153	4.8	4.8
Ibupfrofen	153	4.8	4.8
Ibuprofen Tablets Usp, 200Mg	153	4.8	4.8
Ibuprofen Oral	153	4.8	4.8
Ibuprofen Capsules 200 Mg	153	4.8	4.8
Ibuprofen 200 Mg	153	4.8	4.8
Ibuprofen 200Mg	153	4.8	4.8
Selexipag	20	4.7	4.7
Ibuprofen	201	4.7	4.7
Voriconazole	23	4.6	4.6
Teduglutide	10	4.5	4.5
Mycophenolic Acid	23	4.4	4.4
Baclofen	61	4.4	4.4
Tizanidine	17	4.4	4.4
Oxybutynin Chloride	6	4.2	4.2
Isosorbide Mononitrate	14	4.1	4.1
Bosutinib	6	4.1	4.1
Thyroid, Porcine	7	4.0	4.0
Loperamide Hydrochloride And Dimethicone	21	4.0	4.0
Fesoterodine Fumarate	7	3.9	3.9
Modafinil	20	3.8	3.8
Vancomycin	34	3.6	3.6
Amantadine	9	3.5	3.5
Oxybutynin	17	3.5	3.5
Fosaprepitant Dimeglumine	8	3.5	3.5
Levodopa	7	3.5	3.5
Avapritinib	7	3.5	3.5
Ranolazine	6	3.5	3.5
Acetaminophen And Codeine	7	3.5	3.5
Glatiramer Acetate	34	3.5	3.5
Siponimod	5	3.4	3.4
Droxidopa	12	3.4	3.4
Hydrocodone Bitartrate And Acetaminophen	31	3.4	3.4
Polyethylene Glycol 3350	52	3.3	3.3
Isopropyl Alcohol	18	3.3	3.3
Hydromorphone Hydrochloride	48	3.2	3.2
Armodafinil	11	3.2	3.2
Cladribine	5	3.2	3.2
Panitumumab	8	3.1	3.1
Liraglutide	25	3.1	3.1
Oxycodone	93	3.1	3.1
Levocetirizine Dihydrochloride	12	3.0	3.0
Mirabegron	19	3.0	3.0
Alcohol	19	3.0	3.0
Pioglitazone	21	3.0	3.0
Dimethyl Fumarate	59	3.0	3.0
Amphetamine	4	2.9	2.9
Ethyl Alcohol	13	2.9	2.9
Rivastigmine	9	2.9	2.9
Fingolimod Hcl	41	2.9	2.9
Nicotine Polacrilex	18	2.9	2.9
Vedolizumab	40	2.8	2.8
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	14	2.7	2.8
Niraparib	10	2.7	2.7
Oxycodone Hydrochloride	96	2.7	2.7
Macitentan	30	2.7	2.7
Vilazodone Hydrochloride	4	2.6	2.6
Oral Semaglutide	31	2.6	2.6
Nicotine	17	2.6	2.6
Docetaxel Anhydrous	28	2.5	2.5
Docetaxel	28	2.5	2.5
Pertuzumab	11	2.5	2.5
Morphine Sulfate	48	2.4	2.4
Dronedarone	4	2.4	2.4
Sunitinib Malate	15	2.3	2.3
Oxaliplatin	28	2.3	2.3
Vibegron	3	2.3	2.3
Inclisiran	3	2.3	2.3
Trifluridine And Tipiracil	4	2.3	2.3
Ustekinumab	37	2.2	2.2
Iohexol	3	2.2	2.2
Ozanimod Hydrochloride	3	2.2	2.2
Cenobamate	3	2.2	2.2
Alirocumab	9	2.2	2.2
Teriparatide	39	2.1	2.1
Alpelisib	3	2.1	2.1
Rucaparib	3	2.1	2.1
Tafamidis	4	2.1	2.1
Interferon Beta-1A	65	2.1	2.1
Dabrafenib	7	2.0	2.0
Trametinib	8	2.0	2.0
Acalabrutinib	4	2.0	2.0
Tapentadol Hydrochloride	11	2.0	2.0
Naltrexone	10	2.0	2.0
Carfilzomib	9	1.9	1.9
Suvorexant	4	1.9	1.9
Dulaglutide	27	1.9	1.9
Pazopanib Hydrochloride	8	1.8	1.8
Abiraterone	4	1.8	1.8
Pseudoephedrine Hydrochloride	3	1.8	1.8
Enzalutamide	17	1.8	1.8
Natalizumab	52	1.8	1.8
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	1.7	1.7
Pseudoephedrine Hcl	3	1.7	1.7
Sarilumab	7	1.6	1.6
Fremanezumab-Vfrm	3	1.6	1.6
Aflibercept	8	1.6	1.6
Cannabidiol	6	1.6	1.6
Relugolix	6	1.5	1.5
Orlistat	5	1.2	1.2
Nirmatrelvir And Ritonavir	9	1.0	1.0
Apremilast	24	1.0	1.0
Tirzepatide	23	0.9	0.9
Voxelotor	3	0.8	0.8
Pimavanserin Tartrate	7	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.