Reaction

Foot Operation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,854 reports · 180 co-occurring drugs

As of the last recalculation, Foot Operation appears in 4,854 FAERS reports alongside 180 co-occurring drug terms. The strongest observed disproportionality signal is CORTISONE ACETATE (PRR 34.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Cortisone Acetate	98	34.7	35.0
Diclofenac Potassium, Film Coated	50	25.7	25.9
Diclofenac Potassium Tablets	50	25.7	25.9
Desoximetasone	102	23.4	23.5
Anakinra	88	23.1	23.3
Diclofenac Potassium	52	20.8	20.9
Risedronate Sodium	132	18.7	18.8
Upadacitinib	321	18.0	18.1
Ibuprofen And Diphenhydramine Citrate	89	16.7	16.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	33	16.5	16.6
Leflunomide	344	15.1	15.1
Naproxen Sodium Tablet, Coated	47	15.0	15.1
Naproxen Sodium, Coated Tablets	47	15.0	15.1
Naproxen Sodium 220Mg	47	15.0	15.0
Diltiazem Hydrochloride Extended-Release Tablets	32	12.1	12.2
Hydroxychloroquine Sulfate	234	11.5	11.5
Human Immunoglobulin G	53	11.1	11.2
Golimumab	205	10.7	10.7
Alendronate Sodium	227	10.1	10.1
Triamcinolone Acetonide Ointment Usp, 0.05%	54	10.0	10.0
Certolizumab Pegol	259	10.0	10.0
Sodium Oxybate	138	9.2	9.2
Hydroxychloroquine	155	9.2	9.2
Naproxen	162	9.1	9.1
Risankizumab-Rzaa	165	8.9	8.9
Abatacept	271	8.8	8.8
Calcium Gluconate	24	8.6	8.6
Esomeprazole Magnesium Capsule, Delayed Release	28	8.3	8.3
Esomeprazole Magnesium Delayed Release Capsules	28	8.3	8.3
Esomeprazole Magnesium Dihydrate	28	8.3	8.3
Tofacitinib	324	8.0	8.0
Triamcinolone Acetonide	56	7.9	7.9
Cetirizine Hydrochloride Allergy	52	7.4	7.4
Cetirizine Hydrochloride Tablets	52	7.4	7.4
Sulfasalazine	131	7.4	7.4
Diclofenac Sodium 1%	60	7.3	7.3
Diclofenac Sodium Topical	60	7.3	7.3
Diclofenac Sodium Topical Gel, 1%	60	7.3	7.3
Diclofenac	142	7.3	7.3
Adalimumab-Aaty	77	7.1	7.1
Celecoxib	207	7.0	7.0
Armodafinil	34	7.0	7.0
Adalimumab-Fkjp	73	6.8	6.9
Etanercept	795	6.6	6.6
Adalimumab-Adaz	79	6.5	6.5
Tocilizumab	168	6.5	6.5
Methotrexate	533	6.0	6.0
Diltiazem Hydrochloride	47	5.9	5.9
Naproxen Sodium	188	5.8	5.8
Ascorbic Acid	31	5.7	5.8
Methotrexate Sodium	577	5.6	5.6
Tramadol Hydrochloride	45	5.2	5.2
Trimethoprim	14	5.1	5.1
Belimumab	37	5.0	5.0
Adalimumab	705	4.8	4.8
Tizanidine Hydrochloride	20	4.8	4.8
Diclofenac Sodium	161	4.7	4.7
Meperidine Hydrochloride	10	4.7	4.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	38	4.6	4.6
Primidone	11	4.6	4.6
Tizanidine	25	4.5	4.5
Thyroid, Porcine	11	4.4	4.4
Cyclobenzaprine Hydrochloride	9	4.3	4.3
Modafinil	32	4.3	4.3
Cetirizine	76	4.3	4.3
Infliximab	208	4.2	4.2
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	40	4.2	4.2
Folic Acid	233	4.2	4.2
Bupropion Hydrochloride	94	4.1	4.1
Biotin	30	4.1	4.1
Pramipexole	14	3.9	3.9
Vitamin C	83	3.9	3.9
Hydroxyzine Hydrochloride	12	3.9	3.9
Hydroxyzine Hydrochloride Oral	12	3.9	3.9
Cetirizine Hcl	8	3.7	3.7
Etonogestrel And Ethinyl Estradiol	19	3.7	3.7
Meloxicam	49	3.6	3.6
Sucralfate Oral	12	3.6	3.6
Sucralfate Oral Suspension	12	3.6	3.6
Ibuprofen	220	3.6	3.6
Infliximab-Dyyb	24	3.5	3.5
Meclizine Hcl 12.5Mg	11	3.5	3.5
Meclizine Hcl 25Mg	11	3.5	3.5
Meclizine Hcl 12.5 Mg	11	3.5	3.5
Meclizine Hcl 25 Mg	11	3.5	3.5
Bimekizumab	17	3.4	3.4
Sarilumab	21	3.4	3.4
Rizatriptan Benzoate	8	3.4	3.4
Pseudoephedrine Hydrochloride	8	3.3	3.3
Ibuprofen Capsule	149	3.3	3.3
Ibuprofen Tablet, Film Coated	149	3.3	3.3
Ibupfrofen	149	3.3	3.3
Ibuprofen Tablets Usp, 200Mg	149	3.3	3.3
Ibuprofen Oral	149	3.3	3.3
Ibuprofen Capsules 200 Mg	149	3.3	3.3
Ibuprofen 200 Mg	149	3.3	3.3
Ibuprofen 200Mg	149	3.3	3.3
Teriflunomide	34	3.2	3.2
Cariprazine	7	3.2	3.2
Vibegron	6	3.2	3.2
Rituximab	153	3.2	3.2
Meclizine	12	3.2	3.2
Benzonatate	12	3.1	3.1
Pseudoephedrine Hcl	8	3.1	3.1
Icosapent Ethyl	6	3.0	3.0
Cetirizine Hydrochloride	111	2.9	2.9
Conjugated Estrogens	39	2.9	2.9
Oxycodone And Acetaminophen Tablets	8	2.9	2.9
Estrogens, Conjugated	39	2.8	2.8
Doxyclycline Hyclate	11	2.8	2.8
Pancrelipase	24	2.7	2.7
Estradiol Gel 0.1%	28	2.7	2.7
Estradiol Transdermal	28	2.7	2.7
Esketamine Hydrochloride	11	2.6	2.6
Raloxifene Hydrochloride	9	2.6	2.6
Azelastine	11	2.6	2.6
Pravastatin Sodium	12	2.6	2.6
Hydrocodone Bitartrate And Acetaminophen	34	2.6	2.6
Estradiol	52	2.6	2.6
Linaclotide	16	2.6	2.6
Insulin Glulisine	6	2.5	2.5
Lovastatin	15	2.5	2.5
Cenegermin-Bkbj	7	2.5	2.5
Testosterone Cypionate	5	2.4	2.4
Umeclidinium	5	2.4	2.4
Naltrexone	17	2.4	2.4
Eptinezumab-Jjmr	5	2.4	2.4
Oral Semaglutide	40	2.3	2.3
Tofacitinib Citrate	7	2.3	2.3
Oxymorphone Hydrochloride	6	2.2	2.2
Patiromer	7	2.2	2.2
Canagliflozin	15	2.2	2.2
Teriparatide	56	2.1	2.1
Rotigotine	7	2.1	2.1
Desvenlafaxine Succinate	13	2.1	2.1
Tolvaptan	7	2.1	2.1
Oxybutynin	14	2.1	2.1
Bosentan	24	2.0	2.0
Conjugated Estrogens And Medroxyprogesterone Acetate	11	2.0	2.0
Ibrutinib	37	2.0	2.0
Fluticasone Propionate And Salmeterol	19	2.0	2.0
Glecaprevir And Pibrentasvir	5	2.0	2.0
Tiotropium Bromide Inhalation Spray	5	1.9	1.9
Brivaracetam	4	1.9	1.9
Vilazodone Hydrochloride	4	1.9	1.9
Agalsidase Beta	4	1.9	1.9
Crisaborole	4	1.8	1.8
Naproxen Sodium Tablet	22	1.8	1.8
Fexofenadine Hydrochloride	9	1.8	1.8
Avapritinib	5	1.8	1.8
Dalfampridine	29	1.7	1.7
Rimegepant Sulfate	5	1.7	1.7
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	16	1.7	1.7
Ranolazine	4	1.6	1.6
Dofetilide	4	1.6	1.6
Umeclidinium Bromide And Vilanterol Trifenatate	6	1.5	1.5
Alirocumab	9	1.5	1.5
Vortioxetine	6	1.5	1.5
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	1.5	1.5
Methylphenidate	10	1.5	1.5
Acetaminophen, Aspirin, And Caffeine	7	1.4	1.4
Ambrisentan	40	1.4	1.4
Dupilumab	152	1.4	1.4
Denosumab	63	1.3	1.3
Brexpiprazole	5	1.3	1.3
Varenicline Tartrate	23	1.2	1.2
Dimethyl Fumarate	35	1.2	1.2
Valbenazine	7	1.2	1.2
Abaloparatide	8	1.2	1.2
Fremanezumab-Vfrm	3	1.1	1.1
Relugolix	6	1.1	1.1
Apremilast	37	1.1	1.1
Glatiramer Acetate	15	1.1	1.1
Ixekizumab	9	1.0	1.0
Droxidopa	5	1.0	1.0
Guselkumab	8	1.0	1.0
Pimavanserin Tartrate	10	0.8	0.8
Cinacalcet Hydrochloride	8	0.7	0.7
Evolocumab	22	0.6	0.6
Copper	3	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.