OpenPV Signal Explorer
FAERS disproportionality dashboard
← All drugs
Drug

Levothyroxine Sodium Anhydrous

1,181 flagged reaction(s) · 480,381 total co-reports · max PRR 354.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Cardiospasm 348 354.4 355.7 signal
2 Immunisation 229 237.9 238.5 signal
3 Palmoplantar Keratoderma 343 192.7 193.4 signal
4 Ejection Fraction 174 89.3 89.4 signal
5 Sensitisation 221 85.4 85.6 signal
6 Total Lung Capacity Abnormal 99 73.9 74.0 signal
7 C-reactive Protein 232 72.2 72.4 signal
8 Neurologic Neglect Syndrome 136 67.4 67.5 signal
9 Pulmonary Vasculitis 122 63.1 63.1 signal
10 Deep Vein Thrombosis Postoperative 399 53.7 53.9 signal
11 Sedation Complication 479 49.8 50.0 signal
12 Multiple Drug Therapy 124 45.4 45.4 signal
13 Atrial Tachycardia 365 43.9 44.1 signal
14 Carotid Artery Thrombosis 137 40.1 40.2 signal
15 Mite Allergy 99 38.5 38.6 signal
16 Spirometry Abnormal 89 37.5 37.5 signal
17 Pruritus Genital 352 37.4 37.5 signal
18 Anti-cyclic Citrullinated Peptide Antibody 100 37.0 37.0 signal
19 Lupus Vulgaris 169 34.7 34.8 signal
20 Polycystic Ovaries 223 34.7 34.8 signal
21 Creatinine Renal Clearance Decreased 523 31.3 31.5 signal
22 Swollen Joint Count Increased 393 30.2 30.4 signal
23 Catarrh 105 28.1 28.1 signal
24 Schizoaffective Disorder 210 27.8 27.9 signal
25 Bronchopulmonary Aspergillosis Allergic 104 26.8 26.9 signal
26 Mycotic Allergy 95 26.6 26.7 signal
27 Steroid Dependence 94 26.1 26.1 signal
28 Antineutrophil Cytoplasmic Antibody Positive 80 25.9 25.9 signal
29 X-ray Abnormal 191 25.1 25.2 signal
30 Rheumatic Fever 450 24.1 24.2 signal
31 Adjustment Disorder 133 23.8 23.8 signal
32 Carotid Artery Occlusion 369 23.5 23.6 signal
33 Dust Allergy 96 23.2 23.2 signal
34 Systemic Infection 163 22.8 22.8 signal
35 Adjustment Disorder With Depressed Mood 186 21.3 21.4 signal
36 Tension Headache 381 20.4 20.5 signal
37 Product Monitoring Error 123 19.7 19.7 signal
38 Neuritis 131 19.5 19.5 signal
39 Sleep Terror 355 19.3 19.4 signal
40 Conjunctivitis Allergic 113 17.6 17.6 signal
41 Rheumatoid Factor Positive 432 17.0 17.0 signal
42 C-reactive Protein Abnormal 471 16.6 16.7 signal
43 Facet Joint Syndrome 217 15.5 15.5 signal
44 Dislocation Of Vertebra 145 14.6 14.6 signal
45 Duodenal Ulcer Perforation 473 14.4 14.5 signal
46 Rhinitis Allergic 286 14.4 14.5 signal
47 Ejection Fraction Abnormal 79 14.4 14.4 signal
48 Burns Second Degree 110 14.1 14.1 signal
49 Anti-cyclic Citrullinated Peptide Antibody Positive 444 14.0 14.0 signal
50 Blood Thyroid Stimulating Hormone Abnormal 114 13.8 13.9 signal
51 Bradycardia Neonatal 77 13.7 13.8 signal
52 Blood Thyroid Stimulating Hormone Increased 563 13.6 13.7 signal
53 Eosinophilic Granulomatosis With Polyangiitis 121 13.4 13.4 signal
54 Obstructive Sleep Apnoea Syndrome 82 13.1 13.1 signal
55 Peripheral Venous Disease 234 13.0 13.1 signal
56 Personality Disorder 154 13.0 13.0 signal
57 Sleep Disorder Due To General Medical Condition, Insomnia Type 364 12.6 12.6 signal
58 Total Lung Capacity Decreased 89 12.3 12.3 signal
59 Retinitis 88 11.7 11.7 signal
60 Hypothyroidism 1,673 11.6 11.8 signal
61 Blood Calcium Decreased 590 11.6 11.6 signal
62 Respiratory Disorder Neonatal 82 11.4 11.4 signal
63 Respiratory Symptom 144 11.4 11.4 signal
64 Pituitary Tumour Benign 82 11.0 11.0 signal
65 Pericarditis 828 11.0 11.0 signal
66 Muscle Injury 403 10.8 10.9 signal
67 Blood Thyroid Stimulating Hormone Decreased 219 10.6 10.6 signal
68 Facial Pain 426 10.5 10.6 signal
69 Orthostatic Hypotension 813 10.2 10.3 signal
70 Vasculitis 542 10.2 10.3 signal
71 Normochromic Normocytic Anaemia 139 10.2 10.2 signal
72 Subarachnoid Haemorrhage 472 10.2 10.2 signal
73 Helicobacter Infection 470 10.1 10.2 signal
74 Pleuritic Pain 124 9.8 9.8 signal
75 Full Blood Count Abnormal 470 9.8 9.8 signal
76 Thyroid Function Test Abnormal 186 9.8 9.8 signal
77 Autoimmune Disorder 426 9.8 9.8 signal
78 Nasal Obstruction 82 9.7 9.7 signal
79 Recalled Product Administered 381 9.5 9.5 signal
80 Drug Tolerance Decreased 120 9.4 9.4 signal
81 Eyelid Pain 80 9.0 9.0 signal
82 Lip Dry 368 9.0 9.0 signal
83 Sciatica 651 9.0 9.0 signal
84 Folliculitis 413 8.7 8.8 signal
85 Lung Opacity 102 8.6 8.7 signal
86 Cytolytic Hepatitis 127 8.2 8.2 signal
87 Hand Deformity 487 8.1 8.1 signal
88 Bursitis 439 7.9 7.9 signal
89 Live Birth 295 7.7 7.7 signal
90 Pemphigus 440 7.7 7.7 signal
91 Alcohol Poisoning 93 7.6 7.6 signal
92 Hypopnoea 120 7.5 7.5 signal
93 Arteriosclerosis Coronary Artery 223 7.3 7.3 signal
94 Sleep Disorder Due To A General Medical Condition 542 7.3 7.3 signal
95 Forced Expiratory Volume Decreased 95 7.3 7.3 signal
96 Bronchiectasis 223 7.3 7.3 signal
97 Fibromyalgia 808 7.2 7.3 signal
98 Autoimmune Thyroiditis 122 7.0 7.0 signal
99 Pulmonary Fibrosis 614 7.0 7.0 signal
100 Ventricular Tachycardia 532 7.0 7.0 signal
101 Hyperthyroidism 452 6.8 6.8 signal
102 Blood Test Abnormal 435 6.7 6.7 signal
103 Synovitis 549 6.6 6.6 signal
104 Joint Range Of Motion Decreased 401 6.5 6.5 signal
105 Rales 174 6.5 6.5 signal
106 Breast Cancer Stage Iii 192 6.4 6.5 signal
107 Cardiac Murmur 255 6.3 6.3 signal
108 Therapeutic Agent Toxicity 99 6.3 6.3 signal
109 Gangrene 177 6.3 6.3 signal
110 Obstructive Airways Disorder 324 6.3 6.3 signal
111 Anosmia 409 6.1 6.1 signal
112 Cognitive Disorder 1,295 6.0 6.1 signal
113 Seasonal Allergy 388 5.9 5.9 signal
114 Lower Limb Fracture 523 5.9 5.9 signal
115 Infusion Site Haemorrhage 88 5.8 5.9 signal
116 Neurological Symptom 154 5.8 5.9 signal
117 Throat Clearing 100 5.8 5.8 signal
118 Renal Function Test Abnormal 123 5.8 5.8 signal
119 Wound Infection 290 5.7 5.8 signal
120 Grip Strength Decreased 233 5.7 5.7 signal
121 Bone Erosion 94 5.7 5.7 signal
122 Sedation 691 5.7 5.7 signal
123 Gestational Diabetes 124 5.7 5.7 signal
124 Glossodynia 570 5.5 5.5 signal
125 Goitre 103 5.4 5.4 signal
126 Rhinitis 202 5.4 5.4 signal
127 Pulmonary Alveolar Haemorrhage 140 5.4 5.4 signal
128 Arterial Occlusive Disease 195 5.3 5.3 signal
129 Carpal Tunnel Syndrome 346 5.3 5.3 signal
130 Multiple Allergies 193 5.3 5.3 signal
131 Sensory Loss 196 5.2 5.2 signal
132 Thyroid Disorder 370 5.2 5.2 signal
133 Type 2 Diabetes Mellitus 793 5.0 5.1 signal
134 Walking Aid User 155 5.0 5.0 signal
135 Irritable Bowel Syndrome 497 5.0 5.0 signal
136 Hypercholesterolaemia 219 4.9 4.9 signal
137 Small For Dates Baby 113 4.9 4.9 signal
138 Red Blood Cell Sedimentation Rate Increased 250 4.8 4.8 signal
139 Wheezing 1,318 4.8 4.8 signal
140 Diplopia 578 4.8 4.8 signal
141 Infusion Site Swelling 137 4.8 4.8 signal
142 Atrioventricular Block First Degree 97 4.8 4.8 signal
143 Maternal Exposure Timing Unspecified 82 4.7 4.7 signal
144 Obesity 348 4.7 4.7 signal
145 Sleep Apnoea Syndrome 417 4.7 4.7 signal
146 Bundle Branch Block Left 93 4.7 4.7 signal
147 Muscle Twitching 502 4.7 4.7 signal
148 Blood Pressure Inadequately Controlled 131 4.6 4.6 signal
149 Wound 600 4.6 4.6 signal
150 Mobility Decreased 1,544 4.6 4.7 signal
151 Arteriosclerosis 202 4.6 4.6 signal
152 Depressed Level Of Consciousness 837 4.5 4.6 signal
153 Hemiplegia 177 4.5 4.5 signal
154 Atrial Septal Defect 178 4.5 4.5 signal
155 Motor Dysfunction 214 4.5 4.5 signal
156 Ulcer Haemorrhage 142 4.5 4.5 signal
157 Liver Injury 506 4.5 4.5 signal
158 Gingival Pain 166 4.5 4.5 signal
159 Parosmia 157 4.5 4.5 signal
160 Transient Ischaemic Attack 705 4.5 4.5 signal
161 Renal Failure Chronic 161 4.4 4.4 signal
162 Sinus Congestion 277 4.4 4.4 signal
163 Blood Calcium Increased 179 4.4 4.4 signal
164 Exercise Tolerance Decreased 116 4.3 4.3 signal
165 General Physical Health Deterioration 2,318 4.3 4.4 signal
166 Affect Lability 195 4.3 4.3 signal
167 Sputum Discoloured 190 4.3 4.3 signal
168 Erysipelas 100 4.2 4.2 signal
169 Renal Failure Acute 850 4.2 4.2 signal
170 Infusion Site Pain 252 4.2 4.2 signal
171 Hyponatraemia 1,107 4.2 4.2 signal
172 Infusion Site Erythema 163 4.2 4.2 signal
173 Muscle Spasticity 242 4.2 4.2 signal
174 Bundle Branch Block Right 90 4.2 4.2 signal
175 Systemic Lupus Erythematosus 669 4.0 4.1 signal
176 Candidiasis 77 4.0 4.0 signal
177 Vascular Device Infection 85 4.0 4.0 signal
178 Aortic Valve Incompetence 80 4.0 4.0 signal
179 Contraindicated Product Administered 564 4.0 4.0 signal
180 Blood Cholesterol Increased 868 4.0 4.0 signal
181 Coordination Abnormal 259 3.9 3.9 signal
182 Prescribed Overdose 356 3.9 3.9 signal
183 Aspiration 198 3.9 3.9 signal
184 Oedema 983 3.9 3.9 signal
185 Adrenal Insufficiency 217 3.9 3.9 signal
186 Night Sweats 583 3.9 3.9 signal
187 Lip Swelling 599 3.8 3.9 signal
188 Mitral Valve Incompetence 204 3.8 3.9 signal
189 Skin Haemorrhage 260 3.8 3.9 signal
190 Tinnitus 828 3.8 3.9 signal
191 Osteoarthritis 762 3.8 3.8 signal
192 Respiratory Tract Congestion 285 3.8 3.8 signal
193 Colitis Microscopic 84 3.8 3.8 signal
194 Dyspnoea Exertional 667 3.8 3.8 signal
195 Lung Disorder 868 3.8 3.8 signal
196 Labelled Drug-drug Interaction Medication Error 158 3.8 3.8 signal
197 Lower Respiratory Tract Infection 800 3.8 3.8 signal
198 Rash Papular 396 3.8 3.8 signal
199 Hypernatraemia 87 3.7 3.7 signal
200 Diabetic Neuropathy 87 3.7 3.7 signal
201 Oedema Peripheral 2,128 3.7 3.8 signal
202 Impaired Healing 570 3.7 3.7 signal
203 Gastrointestinal Motility Disorder 92 3.7 3.7 signal
204 Hip Arthroplasty 263 3.7 3.7 signal
205 Hypervolaemia 83 3.7 3.7 signal
206 International Normalised Ratio Increased 496 3.7 3.7 signal
207 Drug Level Increased 284 3.7 3.7 signal
208 Liver Disorder 751 3.6 3.6 signal
209 Sinus Disorder 330 3.5 3.6 signal
210 Pain Of Skin 448 3.5 3.5 signal
211 Amnesia 1,082 3.5 3.6 signal
212 Eye Pruritus 545 3.5 3.5 signal
213 Angina Pectoris 475 3.5 3.5 signal
214 Loss Of Personal Independence In Daily Activities 783 3.5 3.5 signal
215 Hemiparesis 279 3.5 3.5 signal
216 Activated Partial Thromboplastin Time Prolonged 83 3.5 3.5 signal
217 Cachexia 83 3.5 3.5 signal
218 Prescribed Underdose 323 3.4 3.5 signal
219 Electrocardiogram Qt Prolonged 581 3.4 3.5 signal
220 Type 1 Diabetes Mellitus 97 3.4 3.4 signal
221 Cystitis 514 3.4 3.4 signal
222 Electrocardiogram Abnormal 126 3.4 3.4 signal
223 Blood Urea Increased 269 3.4 3.4 signal
224 Vitamin D Deficiency 155 3.4 3.4 signal
225 Sinusitis 1,630 3.4 3.4 signal
226 Breath Sounds Abnormal 78 3.4 3.4 signal
227 Asthma 1,770 3.4 3.4 signal
228 Pharyngolaryngeal Pain 85 3.4 3.4 signal
229 Laryngitis 171 3.4 3.4 signal
230 Palpitations 1,830 3.3 3.4 signal
231 Balance Disorder 1,354 3.3 3.4 signal
232 Psoriatic Arthropathy 628 3.3 3.3 signal
233 Gastrooesophageal Reflux Disease 1,250 3.3 3.3 signal
234 Hyperlipidaemia 186 3.3 3.3 signal
235 Blister 868 3.3 3.3 signal
236 Ear Pain 301 3.3 3.3 signal
237 Exostosis 141 3.3 3.3 signal
238 Ventricular Septal Defect 89 3.3 3.3 signal
239 Gait Inability 510 3.3 3.3 signal
240 Diverticulum 111 3.3 3.3 signal
241 Haemoptysis 430 3.3 3.3 signal
242 Tachycardia 1,364 3.3 3.3 signal
243 Granulocytopenia 88 3.3 3.3 signal
244 Malabsorption 79 3.2 3.2 signal
245 Hypomagnesaemia 211 3.2 3.2 signal
246 Hypokalaemia 697 3.2 3.2 signal
247 Eye Pain 833 3.2 3.2 signal
248 Lymphoedema 104 3.2 3.2 signal
249 Electrolyte Imbalance 173 3.2 3.2 signal
250 Upper-airway Cough Syndrome 123 3.2 3.2 signal
251 Anorexia 196 3.2 3.2 signal
252 Muscular Weakness 1,698 3.2 3.2 signal
253 C-reactive Protein Increased 543 3.2 3.2 signal
254 Gamma-glutamyltransferase Increased 331 3.2 3.2 signal
255 Stomatitis 902 3.2 3.2 signal
256 Blepharospasm 92 3.2 3.2 signal
257 Disturbance In Attention 797 3.1 3.2 signal
258 Musculoskeletal Pain 778 3.1 3.1 signal
259 Cataract Operation 87 3.1 3.1 signal
260 Weight Fluctuation 153 3.1 3.1 signal
261 Haematocrit Decreased 293 3.1 3.1 signal
262 Dry Mouth 1,185 3.1 3.1 signal
263 Tricuspid Valve Incompetence 115 3.1 3.1 signal
264 Spinal Osteoarthritis 128 3.1 3.1 signal
265 Hiatus Hernia 188 3.1 3.1 signal
266 Blood Sodium Decreased 271 3.1 3.1 signal
267 Prothrombin Time Prolonged 87 3.1 3.1 signal
268 Hypoxia 504 3.1 3.1 signal
269 Iron Deficiency Anaemia 132 3.1 3.1 signal
270 Hepatic Steatosis 267 3.1 3.1 signal
271 Joint Dislocation 151 3.0 3.1 signal
272 Road Traffic Accident 596 3.0 3.0 signal
273 Angioedema 627 3.0 3.0 signal
274 Knee Arthroplasty 296 3.0 3.0 signal
275 Breast Cancer Stage Ii 119 3.0 3.0 signal
276 Oesophagitis 155 3.0 3.0 signal
277 Hyperkalaemia 491 3.0 3.0 signal
278 Dehydration 1,871 3.0 3.0 signal
279 Cholecystitis Chronic 95 3.0 3.0 signal
280 Drug Interaction 2,214 3.0 3.0 signal
281 Arthropathy 771 2.9 3.0 signal
282 Hypertransaminasaemia 94 2.9 2.9 signal
283 Aphasia 417 2.9 2.9 signal
284 Eating Disorder 294 2.9 2.9 signal
285 Lupus-like Syndrome 124 2.9 2.9 signal
286 Sneezing 307 2.9 2.9 signal
287 Productive Cough 649 2.9 2.9 signal
288 Confusional State 2,217 2.9 3.0 signal
289 Sinus Bradycardia 132 2.9 2.9 signal
290 Polyuria 111 2.9 2.9 signal
291 Oliguria 84 2.9 2.9 signal
292 Blood Albumin Decreased 107 2.9 2.9 signal
293 Ventricular Extrasystoles 140 2.9 2.9 signal
294 Hepatic Enzyme Increased 912 2.9 2.9 signal
295 Blood Potassium Increased 217 2.8 2.8 signal
296 Sleep Disorder 934 2.8 2.9 signal
297 Blood Creatinine Increased 872 2.8 2.8 signal
298 Product Prescribing Error 315 2.8 2.8 signal
299 Pregnancy 269 2.8 2.8 signal
300 Hypercalcaemia 164 2.8 2.8 signal
301 Bradycardia 704 2.8 2.8 signal
302 Circulatory Collapse 226 2.8 2.8 signal
303 Hypertension 2,796 2.8 2.9 signal
304 Myopathy 114 2.8 2.8 signal
305 Gastrointestinal Disorder 1,162 2.8 2.8 signal
306 Initial Insomnia 134 2.8 2.8 signal
307 Atrial Fibrillation 1,281 2.8 2.8 signal
308 Hypotension 2,623 2.8 2.8 signal
309 Blood Pressure Diastolic Decreased 97 2.8 2.8 signal
310 Contusion 1,257 2.8 2.8 signal
311 Inappropriate Antidiuretic Hormone Secretion 133 2.8 2.8 signal
312 Left Ventricular Dysfunction 87 2.8 2.8 signal
313 Delirium 450 2.8 2.8 signal
314 Intervertebral Disc Degeneration 121 2.8 2.8 signal
315 Micturition Urgency 147 2.8 2.8 signal
316 Transaminases Increased 287 2.7 2.7 signal
317 Hyperglycaemia 469 2.7 2.7 signal
318 Migraine 1,224 2.7 2.8 signal
319 Hypertensive Crisis 144 2.7 2.7 signal
320 Hospice Care 127 2.7 2.7 signal
321 Hypocalcaemia 243 2.7 2.7 signal
322 Respiratory Tract Infection 334 2.7 2.7 signal
323 Musculoskeletal Stiffness 1,127 2.7 2.7 signal
324 Troponin Increased 97 2.7 2.7 signal
325 Upper Respiratory Tract Infection 593 2.7 2.7 signal
326 Blood Alkaline Phosphatase Increased 319 2.7 2.7 signal
327 Blindness 521 2.7 2.7 signal
328 Skin Laceration 138 2.7 2.7 signal
329 Therapy Non-responder 569 2.7 2.7 signal
330 Gastritis 334 2.7 2.7 signal
331 Grand Mal Convulsion 119 2.7 2.7 signal
332 Abdominal Discomfort 2,123 2.7 2.7 signal
333 Tubulointerstitial Nephritis 237 2.7 2.7 signal
334 Constipation 2,737 2.7 2.7 signal
335 Tenderness 132 2.7 2.7 signal
336 Swollen Tongue 395 2.7 2.7 signal
337 Chest Pain 2,336 2.7 2.7 signal
338 Hepatic Cirrhosis 235 2.7 2.7 signal
339 Onychoclasis 86 2.7 2.7 signal
340 Blood Magnesium Decreased 108 2.7 2.7 signal
341 Ocular Discomfort 135 2.6 2.6 signal
342 Extrasystoles 87 2.6 2.6 signal
343 Discomfort 751 2.6 2.6 signal
344 Abdominal Pain Upper 2,537 2.6 2.7 signal
345 Renal Cyst 98 2.6 2.6 signal
346 Fall 4,079 2.6 2.7 signal
347 Therapeutic Product Effect Decreased 542 2.6 2.6 signal
348 Nail Disorder 106 2.6 2.6 signal
349 Dermatitis Contact 138 2.6 2.6 signal
350 Atrioventricular Block Complete 81 2.6 2.6 signal
351 Nodule 158 2.6 2.6 signal
352 Dysarthria 455 2.6 2.6 signal
353 Diabetes Mellitus Inadequate Control 214 2.6 2.6 signal
354 Haematoma 313 2.6 2.6 signal
355 Petechiae 125 2.5 2.6 signal
356 Pulmonary Hypertension 251 2.5 2.5 signal
357 Disorientation 474 2.5 2.5 signal
358 Hepatitis Acute 77 2.5 2.5 signal
359 Blood Pressure Systolic Increased 233 2.5 2.5 signal
360 Medication Error 658 2.5 2.5 signal
361 Glomerular Filtration Rate Decreased 143 2.5 2.5 signal
362 Oral Pain 265 2.5 2.5 signal
363 Drug Intolerance 1,134 2.5 2.5 signal
364 Cardiomegaly 146 2.5 2.5 signal
365 Temperature Intolerance 120 2.5 2.5 signal
366 Pemphigoid 87 2.5 2.5 signal
367 Pleural Effusion 714 2.5 2.5 signal
368 Arthritis 923 2.5 2.5 signal
369 Rhabdomyolysis 487 2.5 2.5 signal
370 Gout 210 2.5 2.5 signal
371 Vertigo 712 2.5 2.5 signal
372 Inflammation 599 2.5 2.5 signal
373 Atelectasis 113 2.5 2.5 signal
374 Coeliac Disease 114 2.5 2.5 signal
375 Cholecystitis 138 2.5 2.5 signal
376 Urosepsis 107 2.5 2.5 signal
377 Hallucination 867 2.5 2.5 signal
378 Liver Function Test Abnormal 338 2.4 2.5 signal
379 Purpura 102 2.4 2.4 signal
380 Atrial Flutter 92 2.4 2.4 signal
381 Body Height Decreased 124 2.4 2.4 signal
382 Rheumatoid Arthritis 1,294 2.4 2.4 signal
383 Asthenia 4,293 2.4 2.5 signal
384 Hypoglycaemia 554 2.4 2.4 signal
385 Peripheral Swelling 1,750 2.4 2.4 signal
386 Blood Potassium Decreased 343 2.4 2.4 signal
387 Liver Function Test Increased 243 2.4 2.4 signal
388 Rectal Haemorrhage 491 2.4 2.4 signal
389 Haematochezia 627 2.4 2.4 signal
390 Joint Swelling 1,367 2.4 2.4 signal
391 Renal Disorder 529 2.4 2.4 signal
392 Pallor 309 2.4 2.4 signal
393 Anaemia 2,161 2.4 2.4 signal
394 Shock Haemorrhagic 92 2.4 2.4 signal
395 Cholelithiasis 371 2.4 2.4 signal
396 Photophobia 211 2.4 2.4 signal
397 Urinary Tract Infection 1,916 2.4 2.4 signal
398 Decreased Appetite 2,606 2.4 2.4 signal
399 Pulmonary Mass 167 2.4 2.4 signal
400 Respiratory Disorder 336 2.4 2.4 signal
401 Syncope 1,120 2.4 2.4 signal
402 Flushing 1,142 2.4 2.4 signal
403 Musculoskeletal Chest Pain 173 2.4 2.4 signal
404 Lipase Increased 85 2.4 2.4 signal
405 Heart Rate Increased 1,100 2.4 2.4 signal
406 Dizziness Postural 106 2.3 2.3 signal
407 Haemorrhoids 215 2.3 2.3 signal
408 Intentional Product Use Issue 967 2.3 2.3 signal
409 Dyspnoea 6,210 2.3 2.4 signal
410 Atrioventricular Block 85 2.3 2.3 signal
411 Nerve Compression 101 2.3 2.3 signal
412 Alopecia 2,155 2.3 2.3 signal
413 Infusion Related Reaction 721 2.3 2.3 signal
414 Injection Site Irritation 138 2.3 2.3 signal
415 Diverticulitis 301 2.3 2.3 signal
416 Asphyxia 89 2.3 2.3 signal
417 Skin Ulcer 281 2.3 2.3 signal
418 Pericardial Effusion 250 2.3 2.3 signal
419 Increased Tendency To Bruise 100 2.3 2.3 signal
420 Blood Pressure Increased 1,659 2.3 2.3 signal
421 Presyncope 262 2.3 2.3 signal
422 Myositis 97 2.3 2.3 signal
423 Lower Gastrointestinal Haemorrhage 80 2.3 2.3 signal
424 Supraventricular Tachycardia 103 2.3 2.3 signal
425 Chronic Obstructive Pulmonary Disease 560 2.3 2.3 signal
426 Gallbladder Disorder 192 2.3 2.3 signal
427 Myocardial Ischaemia 123 2.3 2.3 signal
428 Acute Respiratory Failure 205 2.3 2.3 signal
429 Insurance Issue 159 2.3 2.3 signal
430 Cough 2,994 2.3 2.3 signal
431 Toxic Skin Eruption 108 2.3 2.3 signal
432 Pelvic Fracture 83 2.3 2.3 signal
433 Upper Gastrointestinal Haemorrhage 179 2.2 2.2 signal
434 Hyperhidrosis 1,364 2.2 2.3 signal
435 Injury 747 2.2 2.2 signal
436 Ear Infection 280 2.2 2.2 signal
437 Clostridium Difficile Colitis 112 2.2 2.2 signal
438 Foot Deformity 117 2.2 2.2 signal
439 Haemoglobin Decreased 1,084 2.2 2.2 signal
440 Anuria 91 2.2 2.2 signal
441 Fatigue 8,159 2.2 2.3 signal
442 Gastroenteritis 153 2.2 2.2 signal
443 Arrhythmia 499 2.2 2.2 signal
444 Sopor 140 2.2 2.2 signal
445 Blood Count Abnormal 161 2.2 2.2 signal
446 Musculoskeletal Discomfort 180 2.2 2.2 signal
447 Bronchitis 777 2.2 2.2 signal
448 Memory Impairment 1,435 2.2 2.2 signal
449 Heart Rate Irregular 237 2.2 2.2 signal
450 Urinary Incontinence 308 2.2 2.2 signal
451 Aspartate Aminotransferase Increased 552 2.2 2.2 signal
452 Haematemesis 264 2.2 2.2 signal
453 Dysphonia 606 2.2 2.2 signal
454 Frequent Bowel Movements 279 2.2 2.2 signal
455 Dyspepsia 1,017 2.2 2.2 signal
456 Bladder Disorder 103 2.2 2.2 signal
457 Melaena 228 2.2 2.2 signal
458 Pyelonephritis 89 2.2 2.2 signal
459 Taste Disorder 207 2.2 2.2 signal
460 Rhinorrhoea 665 2.2 2.2 signal
461 Maternal Drugs Affecting Foetus 80 2.2 2.2 signal
462 Body Temperature Increased 211 2.2 2.2 signal
463 Burning Sensation 722 2.2 2.2 signal
464 Escherichia Infection 84 2.2 2.2 signal
465 Cataract 609 2.2 2.2 signal
466 Flank Pain 96 2.2 2.2 signal
467 Rash Pruritic 553 2.2 2.2 signal
468 Hypoaesthesia 1,536 2.2 2.2 signal
469 Swelling 957 2.2 2.2 signal
470 Cardiac Failure 823 2.2 2.2 signal
471 Oxygen Saturation Decreased 568 2.2 2.2 signal
472 Torsade De Pointes 80 2.2 2.2 signal
473 Throat Irritation 454 2.1 2.2 signal
474 Therapeutic Product Effect Incomplete 718 2.1 2.2 signal
475 Alanine Aminotransferase Increased 623 2.1 2.2 signal
476 Head Injury 320 2.1 2.1 signal
477 Pulmonary Embolism 966 2.1 2.2 signal
478 Sudden Death 108 2.1 2.1 signal
479 Multi-organ Failure 177 2.1 2.1 signal
480 Polyneuropathy 120 2.1 2.1 signal
481 Weight Decreased 2,813 2.1 2.2 signal
482 Diarrhoea 6,473 2.1 2.2 signal
483 Dizziness 4,995 2.1 2.2 signal
484 Myasthenia Gravis 79 2.1 2.1 signal
485 Headache 6,277 2.1 2.2 signal
486 Blood Creatine Phosphokinase Increased 293 2.1 2.1 signal
487 Full Blood Count Decreased 201 2.1 2.1 signal
488 Gastrointestinal Infection 89 2.1 2.1 signal
489 Restlessness 365 2.1 2.1 signal
490 Sluggishness 101 2.1 2.1 signal
491 Nasopharyngitis 1,832 2.1 2.1 signal
492 Chest Discomfort 1,009 2.1 2.1 signal
493 Dysphagia 936 2.1 2.1 signal
494 Blood Lactate Dehydrogenase Increased 157 2.1 2.1 signal
495 Feeling Hot 604 2.1 2.1 signal
496 Deep Vein Thrombosis 642 2.1 2.1 signal
497 Nocturia 119 2.1 2.1 signal
498 Insomnia 2,619 2.1 2.1 signal
499 Poor Quality Sleep 210 2.1 2.1 signal
500 Neck Pain 549 2.1 2.1 signal
501 Anxiety 2,798 2.1 2.1 signal
502 Impaired Quality Of Life 141 2.1 2.1 signal
503 Feeling Cold 273 2.1 2.1 signal
504 Red Blood Cell Count Decreased 280 2.1 2.1 signal
505 Blood Pressure Decreased 648 2.1 2.1 signal
506 Weight Increased 2,175 2.1 2.1 signal
507 Joint Stiffness 256 2.1 2.1 signal
508 Epistaxis 731 2.1 2.1 signal
509 Parkinsonism 95 2.1 2.1 signal
510 Ataxia 116 2.1 2.1 signal
511 Peripheral Coldness 134 2.1 2.1 signal
512 Pyrexia 3,364 2.1 2.1 signal
513 Laboratory Test Abnormal 286 2.1 2.1 signal
514 Oral Candidiasis 126 2.0 2.1 signal
515 Anal Incontinence 86 2.0 2.0 signal
516 Haemodialysis 82 2.0 2.0 signal
517 Back Pain 2,244 2.0 2.1 signal
518 Pain In Extremity 2,844 2.0 2.1 signal
519 Secretion Discharge 119 2.0 2.0 signal
520 Lethargy 553 2.0 2.0 signal
521 Paraesthesia 1,516 2.0 2.0 signal
522 Nephropathy 90 2.0 2.0 signal
523 Cellulitis 483 2.0 2.0 signal
524 Foot Fracture 182 2.0 2.0 signal
525 Body Temperature Decreased 95 2.0 2.0 signal
526 Muscle Spasms 1,756 2.0 2.0 signal
527 Vomiting 4,485 2.0 2.1 signal
528 Leukopenia 477 2.0 2.0 signal
529 Rib Fracture 196 2.0 2.0 signal
530 Pancreatitis Acute 213 2.0 2.0 signal
531 Lung Infiltration 85 2.0 2.0 signal
532 Incontinence 101 2.0 2.0 signal
533 Mental Status Changes 265 2.0 2.0 signal
534 Cholestasis 182 2.0 2.0 signal
535 Unresponsive To Stimuli 245 2.0 2.0 signal
536 Caesarean Section 112 2.0 2.0 signal
537 Middle Insomnia 177 2.0 2.0 signal
538 Arthralgia 3,927 2.0 2.0 signal
539 Tooth Infection 125 2.0 2.0 signal
540 Femur Fracture 294 2.0 2.0 signal
541 Palmar-plantar Erythrodysaesthesia Syndrome 221 2.0 2.0 no signal
542 Chromaturia 213 2.0 2.0 no signal
543 Ill-defined Disorder 573 2.0 2.0 no signal
544 Jaundice 254 2.0 2.0 no signal
545 Incorrect Route Of Product Administration 158 2.0 2.0 no signal
546 Covid-19 1,663 2.0 2.0 no signal
547 Blood Pressure Fluctuation 226 2.0 2.0 no signal
548 Eczema 471 2.0 2.0 no signal
549 Accidental Overdose 342 2.0 2.0 no signal
550 Metabolic Acidosis 296 2.0 2.0 no signal
551 Acute Coronary Syndrome 78 2.0 2.0 no signal
552 Osteoporosis 385 2.0 2.0 no signal
553 Injection Site Haematoma 137 2.0 2.0 no signal
554 Leukocytosis 168 2.0 2.0 no signal
555 Renal Impairment 777 2.0 2.0 no signal
556 Hypothermia 94 2.0 2.0 no signal
557 Thyroid Cancer 112 2.0 2.0 no signal
558 Condition Aggravated 2,781 1.9 2.0 no signal
559 Malaise 4,040 1.9 2.0 no signal
560 Platelet Count Increased 120 1.9 1.9 no signal
561 Hypotonia 92 1.9 1.9 no signal
562 Restless Legs Syndrome 167 1.9 1.9 no signal
563 Sinus Tachycardia 130 1.9 1.9 no signal
564 Immunodeficiency 135 1.9 1.9 no signal
565 Tachypnoea 124 1.9 1.9 no signal
566 Foetal Exposure During Pregnancy 743 1.9 1.9 no signal
567 Myalgia 1,553 1.9 1.9 no signal
568 Drug Toxicity 126 1.9 1.9 no signal
569 Brain Fog 133 1.9 1.9 no signal
570 Feeling Jittery 174 1.9 1.9 no signal
571 Vitamin D Decreased 78 1.9 1.9 no signal
572 Generalised Oedema 112 1.9 1.9 no signal
573 Tremor 1,511 1.9 1.9 no signal
574 Blood Iron Decreased 107 1.9 1.9 no signal
575 Nausea 7,152 1.9 2.0 no signal
576 White Blood Cell Count Increased 348 1.9 1.9 no signal
577 Pneumonia 2,917 1.9 1.9 no signal
578 Urine Output Decreased 79 1.9 1.9 no signal
579 Somnolence 1,812 1.9 1.9 no signal
580 Emphysema 91 1.9 1.9 no signal
581 Pulmonary Congestion 119 1.9 1.9 no signal
582 Visual Impairment 1,105 1.9 1.9 no signal
583 Epilepsy 274 1.9 1.9 no signal
584 Pruritus 3,392 1.9 1.9 no signal
585 Head Discomfort 158 1.9 1.9 no signal
586 Basal Cell Carcinoma 140 1.9 1.9 no signal
587 Hallucination, Visual 188 1.9 1.9 no signal
588 Cardiac Failure Congestive 726 1.9 1.9 no signal
589 Blood Pressure Abnormal 177 1.9 1.9 no signal
590 Ear Discomfort 91 1.9 1.9 no signal
591 Infection 1,281 1.9 1.9 no signal
592 Ageusia 222 1.9 1.9 no signal
593 Skin Infection 99 1.9 1.9 no signal
594 Product Administration Error 177 1.9 1.9 no signal
595 Pancreatitis 469 1.9 1.9 no signal
596 Joint Injury 189 1.9 1.9 no signal
597 Flatulence 500 1.9 1.9 no signal
598 Oropharyngeal Pain 817 1.9 1.9 no signal
599 Myoclonus 105 1.9 1.9 no signal
600 Abdominal Pain 2,046 1.9 1.9 no signal
601 Influenza Like Illness 727 1.9 1.9 no signal
602 Coagulopathy 146 1.9 1.9 no signal
603 Nightmare 305 1.9 1.9 no signal
604 Economic Problem 135 1.9 1.9 no signal
605 Abdominal Pain Lower 222 1.9 1.9 no signal
606 Thirst 156 1.8 1.9 no signal
607 Aphonia 122 1.8 1.8 no signal
608 Eye Infection 98 1.8 1.8 no signal
609 Hernia 168 1.8 1.8 no signal
610 Heart Rate Decreased 308 1.8 1.8 no signal
611 Blood Bilirubin Increased 236 1.8 1.8 no signal
612 Depressed Mood 458 1.8 1.8 no signal
613 Gait Disturbance 1,670 1.8 1.9 no signal
614 Hypersomnia 249 1.8 1.8 no signal
615 Lactic Acidosis 279 1.8 1.8 no signal
616 Maternal Exposure During Pregnancy 766 1.8 1.8 no signal
617 Fluid Retention 441 1.8 1.8 no signal
618 Lymphopenia 122 1.8 1.8 no signal
619 Lacrimation Increased 259 1.8 1.8 no signal
620 Intervertebral Disc Protrusion 190 1.8 1.8 no signal
621 Gastric Ulcer 165 1.8 1.8 no signal
622 Malnutrition 96 1.8 1.8 no signal
623 Spinal Fracture 172 1.8 1.8 no signal
624 Cholecystectomy 98 1.8 1.8 no signal
625 Sensory Disturbance 139 1.8 1.8 no signal
626 Retching 183 1.8 1.8 no signal
627 Ulcer 137 1.8 1.8 no signal
628 Pancytopenia 479 1.8 1.8 no signal
629 Hepatitis 220 1.8 1.8 no signal
630 Wrist Fracture 103 1.8 1.8 no signal
631 Feeling Abnormal 2,066 1.8 1.8 no signal
632 Coronary Artery Disease 261 1.8 1.8 no signal
633 Acute Myocardial Infarction 253 1.8 1.8 no signal
634 Pain 5,233 1.8 1.8 no signal
635 Dysuria 313 1.8 1.8 no signal
636 Thrombocytopenia 947 1.8 1.8 no signal
637 Gastrointestinal Pain 93 1.8 1.8 no signal
638 Platelet Count Decreased 904 1.8 1.8 no signal
639 Ejection Fraction Decreased 132 1.8 1.8 no signal
640 Hot Flush 639 1.8 1.8 no signal
641 Localised Infection 205 1.8 1.8 no signal
642 Drug Hypersensitivity 1,645 1.8 1.8 no signal
643 Renal Failure 1,133 1.8 1.8 no signal
644 Apathy 123 1.8 1.8 no signal
645 Pain In Jaw 240 1.8 1.8 no signal
646 Blood Triglycerides Increased 150 1.8 1.8 no signal
647 Neuralgia 204 1.8 1.8 no signal
648 Salivary Hypersecretion 84 1.8 1.8 no signal
649 Back Injury 91 1.8 1.8 no signal
650 Rash Maculo-papular 186 1.8 1.8 no signal
651 Impaired Work Ability 180 1.8 1.8 no signal
652 Pneumonia Aspiration 209 1.8 1.8 no signal
653 Pharmaceutical Product Complaint 220 1.8 1.8 no signal
654 Depression 1,908 1.8 1.8 no signal
655 Hypokinesia 121 1.8 1.8 no signal
656 Pneumonitis 225 1.8 1.8 no signal
657 Ankle Fracture 129 1.8 1.8 no signal
658 Hip Fracture 267 1.8 1.8 no signal
659 Serotonin Syndrome 159 1.8 1.8 no signal
660 Kidney Infection 163 1.8 1.8 no signal
661 Hepatomegaly 82 1.8 1.8 no signal
662 Dysstasia 243 1.8 1.8 no signal
663 Subdural Haematoma 119 1.8 1.8 no signal
664 Nasal Congestion 484 1.7 1.8 no signal
665 Skin Reaction 116 1.7 1.7 no signal
666 Abdominal Distension 855 1.7 1.7 no signal
667 Mania 135 1.7 1.7 no signal
668 Ischaemic Stroke 146 1.7 1.7 no signal
669 Convulsion 473 1.7 1.7 no signal
670 Face Oedema 138 1.7 1.7 no signal
671 Abasia 204 1.7 1.7 no signal
672 White Blood Cell Count Decreased 881 1.7 1.7 no signal
673 Dementia 226 1.7 1.7 no signal
674 Muscle Rigidity 97 1.7 1.7 no signal
675 Splenomegaly 95 1.7 1.7 no signal
676 Hypersensitivity 1,503 1.7 1.7 no signal
677 Pharyngitis 101 1.7 1.7 no signal
678 Ventricular Fibrillation 90 1.7 1.7 no signal
679 Tooth Fracture 89 1.7 1.7 no signal
680 Faeces Discoloured 175 1.7 1.7 no signal
681 Loss Of Consciousness 1,034 1.7 1.7 no signal
682 Gastroenteritis Viral 146 1.7 1.7 no signal
683 Urinary Retention 268 1.7 1.7 no signal
684 Cold Sweat 142 1.7 1.7 no signal
685 Dysgeusia 600 1.7 1.7 no signal
686 Pulmonary Oedema 360 1.7 1.7 no signal
687 Bone Pain 470 1.7 1.7 no signal
688 Dry Skin 1,054 1.7 1.7 no signal
689 Treatment Noncompliance 435 1.7 1.7 no signal
690 Agranulocytosis 148 1.7 1.7 no signal
691 Eye Disorder 262 1.7 1.7 no signal
692 Candida Infection 133 1.7 1.7 no signal
693 Acute Respiratory Distress Syndrome 141 1.7 1.7 no signal
694 Thrombosis 643 1.7 1.7 no signal
695 Cardiac Disorder 745 1.7 1.7 no signal
696 Cardiomyopathy 117 1.7 1.7 no signal
697 Adverse Drug Reaction 707 1.7 1.7 no signal
698 Post Procedural Complication 152 1.7 1.7 no signal
699 Eosinophilia 138 1.7 1.7 no signal
700 Chills 927 1.7 1.7 no signal
701 Agitation 581 1.7 1.7 no signal
702 Colitis 297 1.7 1.7 no signal
703 Ileus 97 1.7 1.7 no signal
704 Scar 135 1.7 1.7 no signal
705 Osteopenia 120 1.7 1.7 no signal
706 Influenza 878 1.7 1.7 no signal
707 Eye Swelling 290 1.7 1.7 no signal
708 Glaucoma 151 1.7 1.7 no signal
709 Pollakiuria 326 1.7 1.7 no signal
710 Neuroleptic Malignant Syndrome 93 1.7 1.7 no signal
711 Rash 3,384 1.6 1.7 no signal
712 Ligament Sprain 77 1.6 1.6 no signal
713 Encephalopathy 191 1.6 1.6 no signal
714 Oral Discomfort 108 1.6 1.6 no signal
715 Ovarian Cyst 78 1.6 1.6 no signal
716 Diabetes Mellitus 592 1.6 1.6 no signal
717 Tooth Abscess 79 1.6 1.6 no signal
718 Pulmonary Thrombosis 84 1.6 1.6 no signal
719 Brain Oedema 97 1.6 1.6 no signal
720 Rotator Cuff Syndrome 99 1.6 1.6 no signal
721 Limb Injury 208 1.6 1.6 no signal
722 Swelling Face 498 1.6 1.6 no signal
723 Back Disorder 125 1.6 1.6 no signal
724 Renal Tubular Necrosis 75 1.6 1.6 no signal
725 Viral Infection 253 1.6 1.6 no signal
726 Transfusion 80 1.6 1.6 no signal
727 Diarrhoea Haemorrhagic 71 1.6 1.6 no signal
728 Dry Eye 367 1.6 1.6 no signal
729 Activities Of Daily Living Impaired 152 1.6 1.6 no signal
730 Sepsis 843 1.6 1.6 no signal
731 Haematuria 259 1.6 1.6 no signal
732 Septic Shock 326 1.6 1.6 no signal
733 Intentional Product Misuse 654 1.6 1.6 no signal
734 Limb Discomfort 233 1.6 1.6 no signal
735 Rash Macular 262 1.6 1.6 no signal
736 Skin Exfoliation 625 1.6 1.6 no signal
737 Dental Caries 83 1.6 1.6 no signal
738 Hepatic Failure 227 1.6 1.6 no signal
739 Blood Urine Present 143 1.6 1.6 no signal
740 Vitreous Floaters 73 1.6 1.6 no signal
741 Urticaria 1,246 1.6 1.6 no signal
742 Dry Throat 76 1.6 1.6 no signal
743 Blood Glucose Fluctuation 82 1.6 1.6 no signal
744 Hypophagia 189 1.6 1.6 no signal
745 Psychomotor Hyperactivity 124 1.6 1.6 no signal
746 Eyelid Oedema 87 1.6 1.6 no signal
747 Pruritus Generalised 163 1.6 1.6 no signal
748 Illness 745 1.6 1.6 no signal
749 Herpes Zoster 426 1.6 1.6 no signal
750 Decreased Activity 79 1.6 1.6 no signal
751 Proteinuria 139 1.6 1.6 no signal
752 Skin Fissures 139 1.6 1.6 no signal
753 Laceration 70 1.5 1.5 no signal
754 Gastrointestinal Haemorrhage 616 1.5 1.5 no signal
755 Feeding Disorder 146 1.5 1.5 no signal
756 Bacterial Infection 136 1.5 1.5 no signal
757 Cyst 91 1.5 1.5 no signal
758 Stress 526 1.5 1.5 no signal
759 Toothache 132 1.5 1.5 no signal
760 Erythema Multiforme 68 1.5 1.5 no signal
761 Throat Tightness 197 1.5 1.5 no signal
762 Muscle Tightness 117 1.5 1.5 no signal
763 Mucosal Inflammation 188 1.5 1.5 no signal
764 Blood Glucose Increased 1,363 1.5 1.5 no signal
765 Metastases To Lung 83 1.5 1.5 no signal
766 Respiratory Failure 524 1.5 1.5 no signal
767 Hepatic Encephalopathy 67 1.5 1.5 no signal
768 Nervousness 376 1.5 1.5 no signal
769 Bedridden 94 1.5 1.5 no signal
770 Tooth Disorder 160 1.5 1.5 no signal
771 Product Dose Omission In Error 192 1.5 1.5 no signal
772 Vision Blurred 976 1.5 1.5 no signal
773 Eye Discharge 73 1.5 1.5 no signal
774 Pulmonary Arterial Hypertension 104 1.5 1.5 no signal
775 Speech Disorder 374 1.5 1.5 no signal
776 Respiratory Distress 197 1.5 1.5 no signal
777 Bipolar Disorder 78 1.5 1.5 no signal
778 Pharyngeal Oedema 111 1.5 1.5 no signal
779 Acute Kidney Injury 1,083 1.5 1.5 no signal
780 Coronary Artery Occlusion 98 1.5 1.5 no signal
781 Disability 140 1.5 1.5 no signal
782 Tendonitis 110 1.5 1.5 no signal
783 Neuropathy Peripheral 667 1.5 1.5 no signal
784 Mouth Ulceration 148 1.5 1.5 no signal
785 Dialysis 100 1.5 1.5 no signal
786 Gingival Bleeding 96 1.5 1.5 no signal
787 Staphylococcal Infection 232 1.5 1.5 no signal
788 Small Intestinal Obstruction 86 1.5 1.5 no signal
789 Interstitial Lung Disease 338 1.5 1.5 no signal
790 Photosensitivity Reaction 115 1.5 1.5 no signal
791 Rash Erythematous 327 1.5 1.5 no signal
792 Dyskinesia 283 1.5 1.5 no signal
793 Ascites 205 1.5 1.5 no signal
794 Hereditary Angioedema 73 1.5 1.5 no signal
795 Gastric Disorder 242 1.5 1.5 no signal
796 Lymphocyte Count Decreased 122 1.5 1.5 no signal
797 Exposure During Pregnancy 428 1.5 1.5 no signal
798 Poor Venous Access 71 1.5 1.5 no signal
799 Pneumothorax 109 1.5 1.5 no signal
800 Drug-induced Liver Injury 212 1.4 1.5 no signal
801 Visual Acuity Reduced 230 1.4 1.4 no signal
802 Product Substitution Issue 394 1.4 1.4 no signal
803 Treatment Failure 560 1.4 1.4 no signal
804 Choking 132 1.4 1.4 no signal
805 Upper Limb Fracture 136 1.4 1.4 no signal
806 Skin Lesion 185 1.4 1.4 no signal
807 Eructation 129 1.4 1.4 no signal
808 Rash Generalised 178 1.4 1.4 no signal
809 Drug Eruption 119 1.4 1.4 no signal
810 Spinal Disorder 64 1.4 1.4 no signal
811 Bronchospasm 96 1.4 1.4 no signal
812 Scab 76 1.4 1.4 no signal
813 Paraesthesia Oral 96 1.4 1.4 no signal
814 Hallucination, Auditory 106 1.4 1.4 no signal
815 Cerebrovascular Accident 1,129 1.4 1.4 no signal
816 Cerebral Haemorrhage 237 1.4 1.4 no signal
817 Increased Appetite 124 1.4 1.4 no signal
818 Tooth Extraction 82 1.4 1.4 no signal
819 Eye Haemorrhage 88 1.4 1.4 no signal
820 Squamous Cell Carcinoma 62 1.4 1.4 no signal
821 Movement Disorder 212 1.4 1.4 no signal
822 Mass 92 1.4 1.4 no signal
823 Tendon Rupture 81 1.4 1.4 no signal
824 Fear 177 1.4 1.4 no signal
825 Oral Herpes 126 1.4 1.4 no signal
826 Thinking Abnormal 121 1.4 1.4 no signal
827 Delusion 100 1.4 1.4 no signal
828 Product Use Complaint 100 1.4 1.4 no signal
829 Conjunctivitis 118 1.4 1.4 no signal
830 Dermatitis Allergic 80 1.4 1.4 no signal
831 Lymphadenopathy 227 1.4 1.4 no signal
832 Metastases To Central Nervous System 82 1.3 1.4 no signal
833 Abscess 102 1.3 1.3 no signal
834 Immune System Disorder 84 1.3 1.3 no signal
835 Hepatic Cytolysis 78 1.3 1.3 no signal
836 Breast Pain 68 1.3 1.3 no signal
837 Macular Degeneration 76 1.3 1.3 no signal
838 Toxic Epidermal Necrolysis 96 1.3 1.3 no signal
839 Eye Irritation 354 1.3 1.3 no signal
840 Product Use Issue 1,187 1.3 1.3 no signal
841 Product Dose Omission Issue 1,805 1.3 1.3 no signal
842 Panic Attack 231 1.3 1.3 no signal
843 Neutrophil Count Increased 65 1.3 1.3 no signal
844 Nephrolithiasis 288 1.3 1.3 no signal
845 Skin Disorder 209 1.3 1.3 no signal
846 Scratch 65 1.3 1.3 no signal
847 Febrile Neutropenia 413 1.3 1.3 no signal
848 Spinal Pain 73 1.3 1.3 no signal
849 Myocardial Infarction 1,095 1.3 1.3 no signal
850 Cyanosis 98 1.3 1.3 no signal
851 Ocular Hyperaemia 289 1.3 1.3 no signal
852 Injection Site Extravasation 77 1.3 1.3 no signal
853 Colitis Ulcerative 274 1.3 1.3 no signal
854 Fungal Infection 204 1.3 1.3 no signal
855 Fracture 116 1.3 1.3 no signal
856 Muscle Atrophy 77 1.3 1.3 no signal
857 Acute Hepatic Failure 83 1.3 1.3 no signal
858 Blood Glucose Decreased 294 1.3 1.3 no signal
859 Drug Effect Less Than Expected 86 1.3 1.3 no signal
860 Deafness 159 1.3 1.3 no signal
861 Neoplasm Progression 213 1.3 1.3 no signal
862 Lymphoma 94 1.3 1.3 no signal
863 Erythema 1,245 1.3 1.3 no signal
864 Impaired Driving Ability 69 1.3 1.3 no signal
865 Pharyngeal Swelling 58 1.3 1.3 no signal
866 Skin Discolouration 278 1.3 1.3 no signal
867 Irritability 364 1.3 1.3 no signal
868 Coma 288 1.3 1.3 no signal
869 Cardiogenic Shock 86 1.3 1.3 no signal
870 Mydriasis 77 1.3 1.3 no signal
871 Paranoia 103 1.3 1.3 no signal
872 Altered State Of Consciousness 128 1.3 1.3 no signal
873 Toxicity To Various Agents 994 1.2 1.3 no signal
874 Therapeutic Response Decreased 357 1.2 1.2 no signal
875 End Stage Renal Disease 109 1.2 1.2 no signal
876 Appendicitis 55 1.2 1.2 no signal
877 Shock 135 1.2 1.2 no signal
878 Covid-19 Pneumonia 70 1.2 1.2 no signal
879 Personality Change 55 1.2 1.2 no signal
880 Disseminated Intravascular Coagulation 83 1.2 1.2 no signal
881 Hunger 79 1.2 1.2 no signal
882 Osteomyelitis 106 1.2 1.2 no signal
883 Wrong Technique In Drug Usage Process 215 1.2 1.2 no signal
884 Device Related Infection 90 1.2 1.2 no signal
885 Hyperbilirubinaemia 60 1.2 1.2 no signal
886 Bone Disorder 107 1.2 1.2 no signal
887 Mood Altered 158 1.2 1.2 no signal
888 Respiratory Depression 71 1.2 1.2 no signal
889 Neutrophil Count Decreased 234 1.2 1.2 no signal
890 Renal Pain 61 1.2 1.2 no signal
891 Hypoacusis 248 1.2 1.2 no signal
892 Adverse Event 530 1.2 1.2 no signal
893 Cerebral Infarction 140 1.2 1.2 no signal
894 Impaired Gastric Emptying 73 1.2 1.2 no signal
895 Cardiac Arrest 472 1.2 1.2 no signal
896 Intentional Dose Omission 155 1.2 1.2 no signal
897 Stevens-johnson Syndrome 126 1.2 1.2 no signal
898 Eye Inflammation 53 1.2 1.2 no signal
899 Product Use In Unapproved Indication 1,371 1.2 1.2 no signal
900 Haemorrhage Intracranial 84 1.2 1.2 no signal
901 Quality Of Life Decreased 75 1.2 1.2 no signal
902 Neutropenia 756 1.2 1.2 no signal
903 Therapy Partial Responder 84 1.2 1.2 no signal
904 Hair Texture Abnormal 75 1.2 1.2 no signal
905 Colon Cancer 83 1.2 1.2 no signal
906 Completed Suicide 466 1.2 1.2 no signal
907 Hypoaesthesia Oral 83 1.2 1.2 no signal
908 Abnormal Behaviour 219 1.2 1.2 no signal
909 Diabetic Ketoacidosis 131 1.2 1.2 no signal
910 Myelodysplastic Syndrome 79 1.1 1.1 no signal
911 Crying 199 1.1 1.1 no signal
912 Brain Neoplasm 50 1.1 1.1 no signal
913 No Therapeutic Response 67 1.1 1.1 no signal
914 Status Epilepticus 61 1.1 1.1 no signal
915 Multiple Sclerosis 258 1.1 1.1 no signal
916 Pharyngitis Streptococcal 58 1.1 1.1 no signal
917 Schizophrenia 65 1.1 1.1 no signal
918 Drug Exposure During Pregnancy 183 1.1 1.1 no signal
919 Myocarditis 60 1.1 1.1 no signal
920 Osteonecrosis Of Jaw 132 1.1 1.1 no signal
921 Blood Glucose Abnormal 98 1.1 1.1 no signal
922 Nerve Injury 59 1.1 1.1 no signal
923 Metastases To Bone 86 1.1 1.1 no signal
924 Abnormal Dreams 146 1.1 1.1 no signal
925 Acute Myeloid Leukaemia 81 1.1 1.1 no signal
926 Respiratory Arrest 143 1.1 1.1 no signal
927 Injection Site Nodule 56 1.1 1.1 no signal
928 Bacteraemia 60 1.1 1.1 no signal
929 Metastases To Liver 89 1.1 1.1 no signal
930 Inappropriate Schedule Of Product Administration 896 1.1 1.1 no signal
931 Mental Impairment 123 1.1 1.1 no signal
932 Unevaluable Event 380 1.1 1.1 no signal
933 Aggression 251 1.1 1.1 no signal
934 Cardiovascular Disorder 128 1.1 1.1 no signal
935 Anaphylactic Shock 128 1.1 1.1 no signal
936 Malignant Melanoma 67 1.1 1.1 no signal
937 Intestinal Obstruction 187 1.1 1.1 no signal
938 Hepatic Function Abnormal 185 1.1 1.1 no signal
939 Dystonia 97 1.0 1.0 no signal
940 Therapeutic Response Unexpected 224 1.0 1.0 no signal
941 Injection Site Pruritus 331 1.0 1.0 no signal
942 Product Packaging Issue 46 1.0 1.0 no signal
943 Dermatitis 102 1.0 1.0 no signal
944 Premature Baby 148 1.0 1.0 no signal
945 Anaphylactic Reaction 269 1.0 1.0 no signal
946 Cardio-respiratory Arrest 206 1.0 1.0 no signal
947 Internal Haemorrhage 56 1.0 1.0 no signal
948 Clostridium Difficile Infection 106 1.0 1.0 no signal
949 Leukaemia 46 1.0 1.0 no signal
950 Haemorrhage 509 1.0 1.0 no signal
951 Mental Disorder 212 1.0 1.0 no signal
952 Posterior Reversible Encephalopathy Syndrome 46 1.0 1.0 no signal
953 Lung Infection 76 1.0 1.0 no signal
954 Spinal Operation 58 1.0 1.0 no signal
955 Hair Colour Changes 60 1.0 1.0 no signal
956 Glycosylated Haemoglobin Increased 120 1.0 1.0 no signal
957 Blindness Unilateral 67 1.0 1.0 no signal
958 Chronic Kidney Disease 362 1.0 1.0 no signal
959 Drug Prescribing Error 92 1.0 1.0 no signal
960 Malignant Neoplasm Progression 480 1.0 1.0 no signal
961 Drug Dispensing Error 73 1.0 1.0 no signal
962 Emotional Disorder 146 1.0 1.0 no signal
963 Product Taste Abnormal 63 1.0 1.0 no signal
964 Device Failure 71 1.0 1.0 no signal
965 Nephropathy Toxic 52 1.0 1.0 no signal
966 Drug Effect Decreased 254 1.0 1.0 no signal
967 Off Label Use 4,025 1.0 1.0 no signal
968 Peritonitis 96 1.0 1.0 no signal
969 Post Procedural Haemorrhage 54 1.0 1.0 no signal
970 Intentional Drug Misuse 98 1.0 1.0 no signal
971 Deformity 43 1.0 1.0 no signal
972 Osteonecrosis 152 1.0 1.0 no signal
973 Injection Site Erythema 560 1.0 1.0 no signal
974 Suicide Attempt 275 1.0 1.0 no signal
975 Eyelid Ptosis 46 1.0 1.0 no signal
976 Pneumocystis Jirovecii Pneumonia 45 0.9 0.9 no signal
977 Suicidal Ideation 411 0.9 0.9 no signal
978 Mood Swings 143 0.9 0.9 no signal
979 Psychotic Disorder 132 0.9 0.9 no signal
980 Euphoric Mood 46 0.9 0.9 no signal
981 Retinal Detachment 41 0.9 0.9 no signal
982 Psoriasis 582 0.9 0.9 no signal
983 Injection Site Rash 135 0.9 0.9 no signal
984 Surgery 257 0.9 0.9 no signal
985 Hospitalisation 675 0.9 0.9 no signal
986 Premature Delivery 70 0.9 0.9 no signal
987 Product Dose Omission 288 0.9 0.9 no signal
988 Hepatotoxicity 96 0.9 0.9 no signal
989 Knee Operation 42 0.9 0.9 no signal
990 Injection Site Warmth 89 0.9 0.9 no signal
991 Gastric Haemorrhage 50 0.9 0.9 no signal
992 Libido Decreased 53 0.9 0.9 no signal
993 Bone Marrow Failure 87 0.9 0.9 no signal
994 Musculoskeletal Disorder 81 0.9 0.9 no signal
995 Plasma Cell Myeloma 165 0.9 0.9 no signal
996 Disease Progression 497 0.9 0.9 no signal
997 Product Availability Issue 94 0.9 0.9 no signal
998 Local Swelling 74 0.9 0.9 no signal
999 Intestinal Perforation 47 0.9 0.9 no signal
1000 Pelvic Pain 76 0.9 0.9 no signal
1001 Injection Site Induration 54 0.9 0.9 no signal
1002 Neoplasm 48 0.9 0.9 no signal
1003 Multiple Fractures 69 0.9 0.9 no signal
1004 Multiple Organ Dysfunction Syndrome 116 0.9 0.9 no signal
1005 Therapy Interrupted 283 0.9 0.9 no signal
1006 Madarosis 48 0.9 0.9 no signal
1007 Product Dispensing Error 89 0.9 0.9 no signal
1008 Nervous System Disorder 128 0.9 0.9 no signal
1009 Uveitis 55 0.9 0.9 no signal
1010 Intentional Self-injury 82 0.9 0.9 no signal
1011 Renal Injury 122 0.9 0.9 no signal
1012 Drug Administration Error 126 0.9 0.9 no signal
1013 Anger 137 0.8 0.8 no signal
1014 Drug Ineffective 5,307 0.8 0.8 no signal
1015 Breast Cancer Metastatic 43 0.8 0.8 no signal
1016 Adverse Reaction 53 0.8 0.8 no signal
1017 Brain Injury 40 0.8 0.8 no signal
1018 Vaginal Discharge 40 0.8 0.8 no signal
1019 Accident 47 0.8 0.8 no signal
1020 Hepatocellular Injury 56 0.8 0.8 no signal
1021 Intentional Overdose 251 0.8 0.8 no signal
1022 Anhedonia 104 0.8 0.8 no signal
1023 Abortion Induced 37 0.8 0.8 no signal
1024 Seizure 449 0.8 0.8 no signal
1025 Paralysis 56 0.8 0.8 no signal
1026 Intraocular Pressure Increased 50 0.8 0.8 no signal
1027 Cytokine Release Syndrome 74 0.8 0.8 no signal
1028 Device Dislocation 168 0.8 0.8 no signal
1029 Fluid Overload 57 0.8 0.8 no signal
1030 Cytopenia 46 0.8 0.8 no signal
1031 Poor Quality Product Administered 39 0.8 0.8 no signal
1032 Disease Recurrence 182 0.8 0.8 no signal
1033 Incorrect Dose Administered 856 0.8 0.8 no signal
1034 Product Quality Issue 513 0.8 0.8 no signal
1035 Skin Cancer 82 0.8 0.8 no signal
1036 Neurotoxicity 66 0.8 0.8 no signal
1037 Injection Site Discolouration 47 0.8 0.8 no signal
1038 Withdrawal Syndrome 160 0.8 0.8 no signal
1039 Complication Associated With Device 50 0.8 0.8 no signal
1040 Product Physical Issue 75 0.8 0.8 no signal
1041 Injection Site Reaction 252 0.8 0.8 no signal
1042 Sars-cov-2 Test Positive 49 0.8 0.8 no signal
1043 Drug Level Decreased 37 0.8 0.8 no signal
1044 Neoplasm Malignant 241 0.8 0.8 no signal
1045 Lung Neoplasm Malignant 148 0.8 0.8 no signal
1046 Injection Site Swelling 270 0.7 0.7 no signal
1047 Incorrect Drug Administration Duration 101 0.7 0.7 no signal
1048 Exposure Via Skin Contact 80 0.7 0.7 no signal
1049 Inappropriate Schedule Of Drug Administration 255 0.7 0.7 no signal
1050 Multiple Sclerosis Relapse 241 0.7 0.7 no signal
1051 No Adverse Event 618 0.7 0.7 no signal
1052 Amenorrhoea 58 0.7 0.7 no signal
1053 Underdose 251 0.7 0.7 no signal
1054 Breast Cancer Female 92 0.7 0.7 no signal
1055 Overdose 739 0.7 0.7 no signal
1056 Poisoning 43 0.7 0.7 no signal
1057 Vaginal Haemorrhage 145 0.7 0.7 no signal
1058 Central Nervous System Lesion 47 0.7 0.7 no signal
1059 Tardive Dyskinesia 96 0.7 0.7 no signal
1060 Incorrect Product Administration Duration 68 0.7 0.7 no signal
1061 Device Occlusion 46 0.7 0.7 no signal
1062 Akathisia 45 0.7 0.7 no signal
1063 Drug Dose Omission 551 0.7 0.7 no signal
1064 Injection Site Pain 996 0.7 0.7 no signal
1065 Decreased Immune Responsiveness 32 0.7 0.7 no signal
1066 Therapy Change 31 0.7 0.7 no signal
1067 Menorrhagia 64 0.7 0.7 no signal
1068 Procedural Pain 88 0.7 0.7 no signal
1069 Product Odour Abnormal 33 0.7 0.7 no signal
1070 Application Site Pruritus 71 0.7 0.7 no signal
1071 Device Use Issue 54 0.7 0.7 no signal
1072 Drug Abuse 259 0.7 0.6 no signal
1073 Injection Site Urticaria 75 0.6 0.6 no signal
1074 Inability To Afford Medication 30 0.6 0.6 no signal
1075 Gastrointestinal Carcinoma 28 0.6 0.6 no signal
1076 Injection Site Haemorrhage 241 0.6 0.6 no signal
1077 Tuberculosis 39 0.6 0.6 no signal
1078 Hepatitis C 37 0.6 0.6 no signal
1079 Ovarian Cancer 28 0.6 0.6 no signal
1080 Dermatitis Atopic 151 0.6 0.6 no signal
1081 Skin Burning Sensation 215 0.6 0.6 no signal
1082 Application Site Erythema 79 0.6 0.6 no signal
1083 Myelosuppression 102 0.6 0.6 no signal
1084 Therapeutic Response Shortened 95 0.6 0.6 no signal
1085 Product Prescribing Issue 60 0.6 0.6 no signal
1086 Death 2,510 0.6 0.6 no signal
1087 Rebound Effect 33 0.6 0.6 no signal
1088 Abortion Spontaneous 116 0.6 0.6 no signal
1089 Extrapyramidal Disorder 72 0.6 0.6 no signal
1090 Injection Site Mass 103 0.6 0.6 no signal
1091 Thrombotic Microangiopathy 27 0.6 0.6 no signal
1092 Therapy Cessation 141 0.6 0.6 no signal
1093 Fistula 31 0.6 0.6 no signal
1094 Injection Site Bruising 213 0.6 0.6 no signal
1095 Emotional Distress 326 0.6 0.6 no signal
1096 Application Site Rash 37 0.6 0.6 no signal
1097 Device Malfunction 180 0.6 0.6 no signal
1098 Application Site Irritation 33 0.6 0.6 no signal
1099 Breast Cancer 246 0.5 0.5 no signal
1100 Prostatic Specific Antigen Increased 36 0.5 0.5 no signal
1101 Unintended Pregnancy 27 0.5 0.5 no signal
1102 Drug Resistance 66 0.5 0.5 no signal
1103 Erectile Dysfunction 65 0.5 0.5 no signal
1104 Injection Site Discomfort 26 0.5 0.5 no signal
1105 Tooth Loss 52 0.5 0.5 no signal
1106 Metrorrhagia 43 0.5 0.5 no signal
1107 Peritonitis Bacterial 25 0.5 0.5 no signal
1108 Needle Issue 71 0.5 0.5 no signal
1109 Meningioma 36 0.5 0.5 no signal
1110 Drug Ineffective For Unapproved Indication 133 0.5 0.5 no signal
1111 Generalised Tonic-clonic Seizure 39 0.5 0.5 no signal
1112 Bone Loss 36 0.5 0.5 no signal
1113 Drug Reaction With Eosinophilia And Systemic Symptoms 60 0.5 0.5 no signal
1114 Cytomegalovirus Infection 39 0.5 0.5 no signal
1115 Drug Withdrawal Syndrome 204 0.5 0.5 no signal
1116 Menstruation Irregular 60 0.5 0.5 no signal
1117 Skin Irritation 100 0.5 0.5 no signal
1118 Extra Dose Administered 86 0.5 0.5 no signal
1119 Drug Administered At Inappropriate Site 23 0.5 0.5 no signal
1120 Dysmenorrhoea 28 0.4 0.4 no signal
1121 Acne 162 0.4 0.4 no signal
1122 Ankylosing Spondylitis 27 0.4 0.4 no signal
1123 Haematotoxicity 19 0.4 0.4 no signal
1124 Wrong Technique In Product Usage Process 413 0.4 0.4 no signal
1125 Device Issue 176 0.4 0.4 no signal
1126 Sexual Dysfunction 23 0.4 0.4 no signal
1127 Device Breakage 76 0.4 0.4 no signal
1128 Drug Effect Incomplete 71 0.4 0.4 no signal
1129 Pancreatic Carcinoma 53 0.4 0.4 no signal
1130 Device Leakage 73 0.4 0.4 no signal
1131 Poisoning Deliberate 16 0.4 0.4 no signal
1132 Abnormal Weight Gain 21 0.4 0.4 no signal
1133 Product Packaging Quantity Issue 18 0.3 0.3 no signal
1134 Skeletal Injury 17 0.3 0.3 no signal
1135 Product Adhesion Issue 57 0.3 0.3 no signal
1136 Incorrect Route Of Drug Administration 55 0.3 0.3 no signal
1137 Bone Density Decreased 48 0.3 0.3 no signal
1138 Genital Haemorrhage 19 0.3 0.3 no signal
1139 Unintentional Medical Device Removal 17 0.3 0.3 no signal
1140 Circumstance Or Information Capable Of Leading To Medication Error 47 0.3 0.3 no signal
1141 Breast Cancer Stage I 13 0.3 0.3 no signal
1142 Inflammatory Bowel Disease 13 0.3 0.3 no signal
1143 Device Use Error 45 0.3 0.3 no signal
1144 Embedded Device 13 0.3 0.3 no signal
1145 Application Site Pain 29 0.3 0.3 no signal
1146 Accidental Exposure To Product 130 0.3 0.3 no signal
1147 Device Defective 21 0.3 0.3 no signal
1148 Complication Of Device Removal 22 0.3 0.3 no signal
1149 Gastric Cancer 33 0.3 0.3 no signal
1150 Renal Cancer 56 0.2 0.2 no signal
1151 Product Preparation Error 24 0.2 0.2 no signal
1152 Drug Withdrawal Syndrome Neonatal 17 0.2 0.2 no signal
1153 Expired Product Administered 37 0.2 0.2 no signal
1154 Incorrect Dose Administered By Device 28 0.2 0.2 no signal
1155 Product Administered At Inappropriate Site 20 0.2 0.2 no signal
1156 Wrong Technique In Device Usage Process 50 0.2 0.2 no signal
1157 Device Deployment Issue 13 0.2 0.2 no signal
1158 Menstruation Delayed 11 0.2 0.2 no signal
1159 Product Storage Error 90 0.2 0.2 no signal
1160 Injury Associated With Device 19 0.2 0.2 no signal
1161 Bladder Cancer 54 0.2 0.2 no signal
1162 Prostate Cancer 71 0.2 0.2 no signal
1163 Drug Dependence 141 0.2 0.2 no signal
1164 Drug Effective For Unapproved Indication 24 0.2 0.2 no signal
1165 Product Complaint 20 0.2 0.2 no signal
1166 Oesophageal Carcinoma 22 0.2 0.2 no signal
1167 Device Difficult To Use 44 0.1 0.1 no signal
1168 Hepatic Cancer 16 0.1 0.1 no signal
1169 Gynaecomastia 20 0.1 0.1 no signal
1170 Syringe Issue 11 0.1 0.1 no signal
1171 Device Delivery System Issue 16 0.1 0.1 no signal
1172 Drug Dose Omission By Device 38 0.1 0.1 no signal
1173 Accidental Underdose 7 0.1 0.1 no signal
1174 Device Adhesion Issue 7 0.1 0.1 no signal
1175 Incorrect Product Storage 6 0.1 0.1 no signal
1176 Complication Of Device Insertion 8 0.1 0.1 no signal
1177 Device Expulsion 28 0.1 0.1 no signal
1178 Dependence 19 0.1 0.1 no signal
1179 Sickle Cell Anaemia With Crisis 4 0.1 0.1 no signal
1180 Device Mechanical Issue 3 0.0 0.0 no signal
1181 Colorectal Cancer 9 0.0 0.0 no signal