OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Sedation Complication reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,468 reports · 146 co-occurring drugs

As of the last recalculation, Sedation Complication appears in 2,468 FAERS reports alongside 146 co-occurring drug terms. The strongest observed disproportionality signal is QUINAPRIL HYDROCHLORIDE (PRR 733.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Quinapril Hydrochloride537733.4787.3
Magnesium Hydroxide519411.0427.5
Diltiazem Hydrochloride Extended-Release Tablets433389.0404.5
Oxazepam540270.8277.8
Cyclobenzaprine Hydrochloride242251.7258.7
Amitriptyline Hydrochloride428248.7254.9
Bisacodyl Suppositories302224.1229.5
Biscodyl302222.1227.4
Bisacodyl303206.8211.4
Lactulose550155.4157.7
Diltiazem Hydrochloride433127.8129.4
Zinc314122.9124.5
Zinc Chloride314122.0123.6
Rosuvastatin Calcium349121.5123.1
Cyclobenzaprine548118.8120.1
Zinc Gluconate314115.9117.3
Quinine9698.299.3
Carbamazepine58696.497.3
Nitroglycerin46589.990.7
Levofloxacin46880.581.2
Levofloxacin In 5% Dextrose46880.581.2
Atropine6770.170.6
Atropine Sulfate6854.654.9
Acetaminophen And Codeine7251.351.6
Levothyroxine Sodium Anhydrous47949.850.0
Morphine Sulfate53046.746.9
Phenobarbital7343.744.0
Aripiprazole Oral19442.943.1
Aripiprazole Orally Disintegrating19442.943.1
Midazolam Hydrochloride11537.737.9
Tiotropium Bromide47335.835.9
Asenapine Maleate3534.534.7
Paliperidone9134.134.3
Midazolam9834.134.2
Psyllium Husk3429.429.5
Oxcarbazepine10829.329.3
Haloperidol7326.126.2
Haloperidol Lactate7325.625.7
Acetaminophen Tablet Extended Release58825.225.3
Pain Reliever58825.225.3
Acetaminophen 500Mg58825.225.2
Antacid13024.324.4
Albuterol29923.823.8
Diazepam Oral Solution (Concentrate)22323.123.2
Diazepam Oral22323.123.2
Fentanyl Citrate4622.122.2
Clobazam6221.922.0
Doxepin2521.021.1
Olanzapine23620.420.4
Docusate Sodium 100Mg5620.220.2
Quetiapine Fumarate6719.719.7
Propofol7918.818.8
Risperidone26418.618.7
Diazepam23517.917.9
Doxepin Hydrochloride2617.517.6
Calcium Carbonate13217.517.5
Omeprazole55917.417.4
Aripiprazole22617.017.1
Lurasidone Hydrochloride4116.816.8
Amlodipine Besylate26016.616.6
Furosemide59916.316.4
Levothyroxine Sodium49116.216.2
Sennosides5616.116.2
Ascorbic Acid4215.515.5
Morphine12815.215.2
Vitamin C15415.015.0
Omeprazole Magnesium61115.015.0
Acetaminophen59314.414.4
Rosuvastatin30214.014.1
Guanfacine1314.014.0
Quetiapine28313.913.9
Clozapine18513.413.4
Memantine2113.013.1
Memantine Hydrochloride2113.013.1
Bupivacaine1412.712.7
Paroxetine Hydrochloride Hemihydrate4912.612.7
Donepezil Hydrochloride5312.412.4
Telmisartan2612.412.4
Paroxetine4912.412.4
Sevoflurane1212.212.2
Albuterol Sulfate35711.711.7
Brexpiprazole2211.311.3
Cariprazine1210.910.9
Rocuronium Bromide1510.810.8
Valproate Sodium2510.310.3
Lorazepam20310.310.3
Ziprasidone2110.110.1
Fentanyl11210.010.0
Divalproex Sodium5410.010.0
Pramipexole1810.010.0
Melatonin619.79.7
Paliperidone Palmitate369.69.6
Lithium289.59.5
Lithium Bromatum289.59.5
Brivaracetam109.49.4
Escitslopram639.39.4
Trimethoprim139.39.4
Fosaprepitant Dimeglumine159.29.3
Amlodipine2649.19.1
Felodipine Extended-Release Tablets128.98.9
Felodipine128.98.9
Linagliptin198.88.9
Docusate Sodium598.88.8
Oxymorphone Hydrochloride128.78.7
Meclizine Hcl 12.5Mg148.78.7
Meclizine Hcl 25Mg148.78.7
Meclizine Hcl 12.5 Mg148.78.7
Meclizine Hcl 25 Mg148.78.7
Valproic Acid328.78.7
Cefazolin98.38.4
Meclizine168.38.3
Fluoxetine628.08.0
Hydroxyzine447.97.9
Sertraline1057.87.8
Escitalopram Oxalate667.87.8
Mirtazapine827.87.8
Phenytoin197.77.7
Cefazolin Sodium117.77.7
Baclofen757.57.6
Meclizine Hydrochloride177.47.4
Methylphenidate247.07.1
Lithium Carbonate147.07.0
Cetiirizine346.96.9
Vortioxetine136.56.5
Clonidine386.36.3
Isosorbide Mononitrate156.16.1
Ethyl Alcohol195.95.9
Suvorexant95.95.9
Nebivolol115.85.8
Amantadine105.55.5
Methylphenidate Hydrochloride375.35.3
Norepinephrine Bitartrate95.35.3
Cenobamate55.15.1
Lacosamide225.05.0
Abiraterone85.05.0
Isopropyl Alcohol194.84.8
Norepinephrine64.74.7
Methadone234.64.6
Eszopiclone134.34.3
Alcohol194.24.2
Cannabidiol114.04.0
Methadone Hydrochloride53.93.9
Valbenazine113.73.7
Esketamine Hydrochloride73.33.3
Tapentadol Hydrochloride92.32.3
Pimavanserin Tartrate91.41.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.