Reaction

Adjustment Disorder With Depressed Mood reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,990 reports · 192 co-occurring drugs

As of the last recalculation, Adjustment Disorder With Depressed Mood appears in 1,990 FAERS reports alongside 192 co-occurring drug terms. The strongest observed disproportionality signal is DICLOFENAC POTASSIUM, FILM COATED (PRR 1,294.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diclofenac Potassium, Film Coated	684	1,294.9	1,410.1
Diclofenac Potassium Tablets	684	1,294.0	1,409.0
Diclofenac Potassium	687	1,015.0	1,084.3
Desoximetasone	949	995.0	1,047.4
Pseudoephedrine Hydrochloride	586	845.1	896.4
Cortisone Acetate	635	789.6	832.6
Pseudoephedrine Hcl	586	788.0	832.5
Naproxen Sodium Tablet, Coated	625	703.4	737.5
Naproxen Sodium, Coated Tablets	625	703.4	737.5
Naproxen Sodium 220Mg	625	702.4	736.5
Tofacitinib Citrate	549	604.5	631.0
Chlorhexidine Gluconate	383	542.7	566.5
Cetirizine Hydrochloride Allergy	871	534.2	550.1
Cetirizine Hydrochloride Tablets	871	534.1	550.0
Diclofenac Sodium 1%	942	522.8	537.0
Diclofenac Sodium Topical	942	522.8	537.0
Diclofenac Sodium Topical Gel, 1%	942	521.8	535.9
Acetaminophen And Codeine	391	417.5	431.4
Hydrocortisone Sodium Succinate	291	379.0	391.2
Calcium Gluconate	355	374.8	386.2
Adalimumab-Adaz	956	363.7	370.5
Adalimumab-Fkjp	869	347.6	354.2
Adalimumab-Aaty	868	339.4	345.8
Diclofenac	1,104	299.8	303.7
Sarilumab	541	293.8	300.0
Cetirizine	1,035	289.6	293.5
Doxyclycline Hyclate	349	259.7	265.2
Sulfasalazine	969	251.5	254.7
Quetiapine Fumarate	521	249.8	254.3
Golimumab	978	233.6	236.3
Isopropyl Alcohol	547	233.1	236.9
Alendronate Sodium	1,052	230.2	232.6
Leflunomide	1,042	217.5	219.7
Diltiazem Hydrochloride Extended-Release Tablets	210	215.7	219.8
Alcohol	546	202.4	205.3
Tocilizumab	1,018	190.0	191.7
Calcium Carbonate	754	188.4	190.6
Antacid	599	188.2	190.7
Hydrocortisone Acetate	771	180.5	182.4
Hydroxychloroquine	777	178.0	179.8
Diclofenac Sodium	1,120	176.8	178.1
Cetiirizine	523	174.9	177.0
Aprepitant	254	164.8	167.1
Certolizumab Pegol	938	157.5	158.7
Fosaprepitant Dimeglumine	186	156.0	158.1
Ustekinumab	846	149.7	150.9
Hydroxychloroquine Sulfate	787	148.8	150.1
Risedronate Sodium	352	143.7	145.3
Hydrocortisone	757	142.6	143.8
Triamcinolone Acetonide Ointment Usp, 0.05%	274	141.8	143.5
Cetirizine Hydrochloride	1,046	138.8	139.7
Pantoprazole Sodium In 0.9% Sodium Chloride	581	138.0	139.3
Pantoprazole Sodium Injection	581	138.0	139.3
Oxycodone And Acetaminophen Tablets	145	137.2	138.8
Abatacept	935	132.3	133.2
Methylprednisolone Sodium Succinate	443	128.1	129.3
Diphenhydramine Hydrochloride Capsule, Liquid Filled	231	127.8	129.2
Anti-Itch	558	120.6	121.6
Anti-Pruritic	558	120.6	121.6
Antipruritic (Anti-Itch)	558	120.6	121.6
Cool Relief Gel With Aloe	558	120.6	121.6
Drs. Hydrocortisone	558	120.6	121.6
Hydrocortisone Continuous Spray	558	120.6	121.6
Hydrocortisone Spray	558	120.6	121.6
Anti-Itch Cream	558	120.6	121.6
Hydrocortisone Lotion	558	120.6	121.6
Hydrocortisone Cream 1%	558	120.5	121.5
Hydrocortisone Cream 1/2%	558	120.5	121.5
Hydrocortisone 1%	558	120.5	121.5
Hydrocortisone Cream	558	120.0	121.0
Secukinumab	943	115.3	116.0
Erythromycin	187	115.0	116.1
Rituximab	1,074	114.3	114.9
Naproxen Sodium	871	112.6	113.3
Triamcinolone Acetonide	275	107.9	108.8
Doxycycline Hyclate	510	105.9	106.7
Doxycycline	510	104.8	105.6
Tramadol Hydrochloride	288	93.4	94.1
Infliximab	964	88.6	89.0
Tofacitinib	879	88.5	88.9
Apremilast	765	88.2	88.7
Folic Acid	1,009	84.8	85.2
Celecoxib	696	84.5	84.9
Botulinum Toxin Type A	92	81.2	81.8
Ramipril	625	76.5	76.9
Ascorbic Acid	155	75.5	76.0
Diltiazem Hydrochloride	211	71.2	71.7
Vitamin C	475	70.7	71.1
Oxycodone And Acetaminophen	145	70.1	70.5
Mycophenolate Mofetil Hydrochloride	625	69.6	69.9
Quetiapine	776	68.4	68.7
Mycophenolate Mofetil	612	67.6	67.9
Oxycodone	747	66.3	66.6
Naproxen	394	65.2	65.5
Vedolizumab	406	61.7	62.0
Acetaminophen Tablet Extended Release	857	61.0	61.2
Pantoprazole	853	60.9	61.1
Pain Reliever	857	60.9	61.1
Acetaminophen 500Mg	857	60.9	61.1
Azathioprine	404	59.9	60.2
Meloxicam	283	59.2	59.5
Pantoprazole Sodium	585	58.0	58.3
Mesalamine	267	57.3	57.5
Ibuprofen Capsule	689	54.7	54.9
Ibuprofen Tablet, Film Coated	689	54.7	54.9
Ibupfrofen	689	54.7	54.9
Ibuprofen Tablets Usp, 200Mg	689	54.7	54.9
Ibuprofen Oral	689	54.7	54.9
Ibuprofen Capsules 200 Mg	689	54.7	54.9
Ibuprofen 200 Mg	689	54.7	54.9
Ibuprofen 200Mg	689	54.7	54.9
Magnesium	350	53.8	54.1
Methotrexate	1,044	53.5	53.6
Thiamine Hydrochloride	61	52.8	53.1
Methotrexate Sodium	1,109	52.7	52.8
Lorazepam	595	49.0	49.1
Lansoprazole	581	47.8	47.9
Prednisone	1,072	47.2	47.3
Ibuprofen	747	45.4	45.6
Acetaminophen	978	44.0	44.1
Indomethacin	54	43.8	44.0
Candesartan	137	43.1	43.2
Trimethoprim	47	42.7	42.9
Minocycline	46	42.2	42.4
Calcium	451	40.8	40.9
Adalimumab	1,172	40.7	40.8
Morphine	253	40.5	40.6
Tretinoin	30	39.2	39.4
Sulfamethoxazole And Trimethoprim	271	38.7	38.9
Cyanocobalamin	110	36.9	37.0
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	438	36.4	36.5
Erenumab-Aooe	173	35.9	36.0
Fish Oil	264	35.1	35.2
Atomoxetine Hydrochloride	76	34.7	34.8
Moxifloxacin Hydrochloride	65	34.6	34.7
Alendronate Sodium Tablet	59	34.3	34.4
Methylprednisolone	368	33.9	34.0
Etanercept	976	32.5	32.6
Ergocalciferol	754	32.4	32.4
Lisinopril	639	31.7	31.8
Moxifloxacin	41	31.1	31.1
Oxycodone Hydrochloride	428	26.0	26.0
Pregabalin	507	25.8	25.9
Diphenhydramine Hydrochloride	335	25.2	25.3
Mirabegron	88	24.8	24.9
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	67	23.9	23.9
Oxycodone Hydrochloride And Acetaminophen	203	23.8	23.9
Albuterol	227	22.2	22.2
Prednisolone	313	21.3	21.4
Prednisolone Oral	313	21.3	21.4
Prednisolone Oral Solution	313	21.3	21.4
Levothyroxine Sodium Anhydrous	186	21.3	21.4
Icosapent Ethyl	17	21.1	21.1
Mepolizumab	95	20.9	21.0
Diphenhydramine	108	18.8	18.9
Topiramate	154	18.6	18.7
Salicylic Acid	77	15.8	15.8
Ibuprofen Tablets, Coated	59	14.9	14.9
Ibuprofen Sodium	59	14.8	14.8
Fluticasone Furoate	16	13.9	13.9
Upadacitinib	101	13.6	13.6
Methylprednisolone Acetate	10	13.1	13.1
Albuterol Sulfate	308	12.7	12.7
Cyclobenzaprine	57	12.3	12.3
Cyclobenzaprine Hydrochloride	10	11.7	11.7
Sodium Oxybate	69	11.3	11.3
Morphine Sulfate	123	11.2	11.2
Methocarbamol Tablets	17	10.7	10.7
Armodafinil	21	10.5	10.5
Ranitidine Hydrochloride	52	10.2	10.3
Magnesium Hydroxide	13	10.1	10.2
Buprenorphine	86	10.1	10.1
Lamotrigine	117	9.8	9.8
Lamotirigine	60	9.0	9.0
Lamotrigine Extended-Release	60	9.0	9.0
Lamotrigine Chewable Dispersible	60	9.0	9.0
Anakinra	14	8.9	8.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	7	8.5	8.5
Methocarbamol	18	8.4	8.4
Prednisolone Acetate	7	7.1	7.1
Dexamethasone 1.5 Mg	175	6.8	6.8
Dexamethasone	175	6.7	6.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	22	6.6	6.6
Amphetamine	5	6.3	6.3
Modafinil	19	6.2	6.2
Thyroid, Porcine	6	5.9	5.9
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	23	5.9	5.9
Bupivacaine	5	5.6	5.6
Etonogestrel And Ethinyl Estradiol	10	4.7	4.7
Cariprazine	4	4.5	4.5
Peginterferon Beta-1A	4	3.2	3.2
Copper	3	0.7	0.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.