Reaction

Swollen Joint Count Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,079 reports · 189 co-occurring drugs

As of the last recalculation, Swollen Joint Count Increased appears in 3,079 FAERS reports alongside 189 co-occurring drug terms. The strongest observed disproportionality signal is DESOXIMETASONE (PRR 2,866.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Desoximetasone	2,230	2,866.8	3,249.2
Pseudoephedrine Hydrochloride	1,701	2,499.3	2,998.4
Pseudoephedrine Hcl	1,711	2,361.4	2,798.4
Cortisone Acetate	1,783	2,318.0	2,711.8
Diclofenac Potassium, Film Coated	1,333	1,887.6	2,245.2
Diclofenac Potassium Tablets	1,333	1,886.2	2,243.3
Diclofenac Potassium	1,333	1,469.8	1,677.8
Cetirizine Hydrochloride Allergy	1,972	1,222.5	1,308.2
Cetirizine Hydrochloride Tablets	1,972	1,222.4	1,308.0
Diclofenac Sodium 1%	2,042	1,145.3	1,215.2
Diclofenac Sodium Topical	2,042	1,145.3	1,215.1
Diclofenac Sodium Topical Gel, 1%	2,042	1,143.1	1,212.6
Tofacitinib Citrate	1,240	1,069.8	1,182.2
Naproxen Sodium Tablet, Coated	1,114	870.9	949.3
Naproxen Sodium, Coated Tablets	1,114	870.9	949.3
Naproxen Sodium 220Mg	1,114	869.6	947.9
Diclofenac	2,379	817.8	841.1
Sulfasalazine	2,295	775.8	799.4
Cetirizine	2,278	760.0	783.1
Tocilizumab	2,404	646.1	660.1
Golimumab	2,220	624.6	641.3
Leflunomide	2,321	606.0	619.8
Alendronate Sodium	2,291	596.8	610.7
Sarilumab	1,220	516.5	541.6
Adalimumab-Adaz	1,719	497.3	514.1
Diclofenac Sodium	2,406	490.9	498.9
Adalimumab-Fkjp	1,586	476.3	493.2
Adalimumab-Aaty	1,585	465.5	481.7
Certolizumab Pegol	2,201	442.7	451.2
Chlorhexidine Gluconate	480	420.5	443.9
Calcium Gluconate	596	414.4	436.0
Abatacept	2,226	389.6	396.0
Acetaminophen And Codeine	549	370.5	388.1
Cetirizine Hydrochloride	2,279	356.8	361.8
Hydrocortisone Sodium Succinate	411	340.9	356.6
Ustekinumab	1,892	322.6	328.7
Hydroxychloroquine Sulfate	1,793	317.1	323.5
Rituximab	2,326	301.1	304.4
Hydroxychloroquine	1,580	292.8	299.2
Tofacitinib	2,192	276.3	279.7
Hydrocortisone Acetate	1,443	251.7	256.8
Cetiirizine	1,043	251.2	257.6
Infliximab	2,226	246.1	248.7
Quetiapine Fumarate	791	243.5	250.2
Folic Acid	2,292	240.2	242.4
Isopropyl Alcohol	829	226.5	232.2
Antacid	1,041	223.3	228.3
Doxyclycline Hyclate	468	218.9	225.1
Calcium Carbonate	1,247	210.2	214.2
Alcohol	828	196.9	201.2
Hydrocortisone	1,385	189.8	192.8
Triamcinolone Acetonide Ointment Usp, 0.05%	539	188.4	192.9
Methotrexate Sodium	2,499	180.2	181.2
Methotrexate	2,402	172.0	172.9
Secukinumab	1,749	168.3	170.2
Risedronate Sodium	608	164.5	167.8
Anti-Itch	1,048	159.7	162.2
Anti-Pruritic	1,048	159.7	162.2
Antipruritic (Anti-Itch)	1,048	159.7	162.2
Cool Relief Gel With Aloe	1,048	159.7	162.2
Drs. Hydrocortisone	1,048	159.7	162.2
Hydrocortisone Continuous Spray	1,048	159.7	162.2
Hydrocortisone Spray	1,048	159.7	162.2
Anti-Itch Cream	1,048	159.7	162.2
Hydrocortisone Lotion	1,048	159.7	162.2
Hydrocortisone Cream 1%	1,048	159.6	162.1
Hydrocortisone Cream 1/2%	1,048	159.6	162.1
Hydrocortisone 1%	1,048	159.5	162.0
Hydrocortisone Cream	1,048	158.9	161.4
Doxycycline Hyclate	1,014	150.9	153.2
Doxycycline	1,014	149.3	151.6
Tramadol Hydrochloride	654	148.9	151.5
Triamcinolone Acetonide	539	142.8	145.3
Aprepitant	343	141.2	143.9
Apremilast	1,531	139.7	141.2
Pantoprazole Sodium In 0.9% Sodium Chloride	889	135.9	137.9
Pantoprazole Sodium Injection	889	135.9	137.8
Naproxen Sodium	1,488	135.3	136.7
Prednisone	2,341	128.1	128.7
Acetaminophen Tablet Extended Release	1,875	125.5	126.4
Pain Reliever	1,875	125.5	126.4
Acetaminophen 500Mg	1,875	125.4	126.3
Oxycodone And Acetaminophen Tablets	200	121.2	123.3
Vitamin C	1,073	120.6	122.1
Celecoxib	1,335	120.3	121.5
Fosaprepitant Dimeglumine	219	115.8	117.7
Methylprednisolone Sodium Succinate	612	111.0	112.5
Diltiazem Hydrochloride Extended-Release Tablets	173	108.8	110.5
Adalimumab	2,409	102.2	102.5
Ramipril	1,096	92.3	93.1
Mycophenolate Mofetil Hydrochloride	1,159	91.7	92.5
Mycophenolate Mofetil	1,142	89.8	90.5
Oxycodone	1,363	87.6	88.3
Diphenhydramine Hydrochloride Capsule, Liquid Filled	249	85.6	86.6
Acetaminophen	1,976	81.5	81.9
Ascorbic Acid	252	79.7	80.6
Etanercept	2,151	78.3	78.6
Pantoprazole	1,507	77.9	78.3
Naproxen	675	74.1	74.8
Moxifloxacin Hydrochloride	203	72.4	73.1
Moxifloxacin	141	70.9	71.6
Botulinum Toxin Type A	124	70.3	71.0
Meloxicam	493	68.1	68.7
Quetiapine	1,178	66.3	66.8
Erythromycin	170	64.8	65.4
Oxycodone And Acetaminophen	201	62.3	62.8
Magnesium	604	61.5	62.0
Trimethoprim	101	59.9	60.4
Pantoprazole Sodium	889	56.6	56.9
Ibuprofen Capsule	1,011	50.5	50.8
Ibuprofen Tablet, Film Coated	1,011	50.5	50.8
Ibupfrofen	1,011	50.5	50.8
Ibuprofen Tablets Usp, 200Mg	1,011	50.5	50.8
Ibuprofen Oral	1,011	50.5	50.8
Ibuprofen Capsules 200 Mg	1,011	50.5	50.7
Ibuprofen 200 Mg	1,011	50.5	50.7
Ibuprofen 200Mg	1,011	50.5	50.7
Minocycline	77	45.8	46.1
Calcium	748	44.6	44.9
Lansoprazole	823	42.3	42.5
Fish Oil	471	41.4	41.6
Lorazepam	816	41.4	41.6
Ibuprofen	1,079	40.8	41.0
Pregabalin	1,077	40.6	40.8
Azathioprine	448	40.1	40.3
Cyanocobalamin	175	38.0	38.2
Tretinoin	44	37.2	37.4
Sulfamethoxazole And Trimethoprim	399	36.6	36.8
Mesalamine	274	36.1	36.3
Diltiazem Hydrochloride	173	35.8	35.9
Atomoxetine Hydrochloride	121	35.7	35.9
Candesartan	177	35.5	35.7
Ergocalciferol	1,204	34.1	34.2
Alendronate Sodium Tablet	88	33.0	33.2
Levothyroxine Sodium Anhydrous	393	30.2	30.4
Lisinopril	939	29.4	29.5
Vedolizumab	322	28.1	28.2
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	531	26.9	27.0
Methylprednisolone	468	26.8	26.9
Thiamine Hydrochloride	47	25.9	26.0
Mirabegron	131	23.9	23.9
Morphine	242	23.7	23.8
Prednisolone	520	23.2	23.3
Prednisolone Oral	520	23.2	23.3
Prednisolone Oral Solution	520	23.2	23.3
Oxycodone Hydrochloride	606	23.2	23.3
Erenumab-Aooe	164	21.2	21.3
Icosapent Ethyl	25	20.0	20.1
Fluticasone Furoate	34	19.2	19.2
Oxycodone Hydrochloride And Acetaminophen	252	18.7	18.7
Mepolizumab	125	17.7	17.7
Dexamethasone Sodium Phosphate	26	17.4	17.5
Diphenhydramine Hydrochloride	361	16.5	16.6
Cyclobenzaprine Hydrochloride	21	15.9	15.9
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	63	14.3	14.4
Salicylic Acid	96	12.6	12.7
Indomethacin	24	12.3	12.4
Magnesium Hydroxide	24	12.1	12.1
Diphenhydramine	109	12.1	12.1
Topiramate	157	11.9	12.0
Morphine Sulfate	195	11.5	11.6
Cyclobenzaprine	77	10.7	10.7
Ibuprofen Sodium	66	10.6	10.6
Ibuprofen Tablets, Coated	65	10.5	10.6
Levothyroxine Sodium	402	9.8	9.8
Albuterol	162	9.6	9.6
Buprenorphine	124	9.4	9.4
Lamotirigine	92	8.9	8.9
Lamotrigine Extended-Release	92	8.9	8.9
Lamotrigine Chewable Dispersible	92	8.9	8.9
Trazodone Hydrochloride	20	8.7	8.7
Ranitidine Hydrochloride	68	8.6	8.6
Upadacitinib	101	8.6	8.6
Anakinra	21	8.6	8.6
Dexamethasone 1.5 Mg	323	8.2	8.2
Dexamethasone	323	8.1	8.1
Telmisartan	21	8.0	8.0
Candesartan Cilexetil	30	7.8	7.8
Methylprednisolone Acetate	9	7.6	7.6
Lamotrigine	140	7.5	7.5
Bupropion	47	7.2	7.2
Hydromorphone Hydrochloride	95	7.2	7.2
Bupivacaine	9	6.5	6.5
Fluticasone Propionate Nasal	27	6.1	6.1
Paroxetine Hydrochloride Hemihydrate	24	4.9	4.9
Paroxetine	24	4.8	4.8
Infliximab-Dyyb	19	4.4	4.4
Leucovorin Calcium	12	4.3	4.3
Onabotulinumtoxina	28	2.5	2.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.