Reaction

Tension Headache reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,241 reports · 166 co-occurring drugs

As of the last recalculation, Tension Headache appears in 4,241 FAERS reports alongside 166 co-occurring drug terms. The strongest observed disproportionality signal is FELODIPINE EXTENDED-RELEASE TABLETS (PRR 187.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Felodipine Extended-Release Tablets	394	187.1	193.8
Felodipine	394	187.0	193.8
Amitriptyline Hydrochloride	381	117.0	119.6
Linagliptin	387	114.5	117.0
Isosorbide Dinitrate	368	101.2	103.1
Isosorbide Mononitrate	375	97.3	99.0
Dapagliflozin	388	66.5	67.4
Cetirizine Hydrochloride Allergy	269	46.5	46.9
Cetirizine Hydrochloride Tablets	269	46.5	46.9
Candesartan	289	42.6	42.9
Esomeprazole	402	35.0	35.3
Apixaban	403	32.6	32.8
Candesartan Cilexetil	158	30.6	30.8
Esomeprazole Magnesium Capsule, Delayed Release	88	30.4	30.6
Esomeprazole Magnesium Delayed Release Capsules	88	30.4	30.6
Esomeprazole Magnesium Dihydrate	88	30.2	30.4
Digoxin	401	30.2	30.4
Naproxen	431	29.9	30.0
Cetirizine	414	28.9	29.1
Levothyroxine Sodium Anhydrous	381	20.4	20.5
Cetiirizine	153	18.4	18.4
Naltrexone Hydrochloride And Bupropion Hydrochloride	30	17.4	17.4
Naproxen Sodium	453	17.3	17.4
Bisoprolol Fumarate	431	17.2	17.3
Fexofenadine	57	17.1	17.2
Hydrochlorothiazide	434	16.2	16.3
Cetirizine Hydrochloride	448	14.8	14.8
Bumetanide	77	14.6	14.6
Lansoprazole	469	14.4	14.4
Sotalol Hydrochloride	48	14.3	14.4
Apremilast	366	13.3	13.4
Losartan	408	12.6	12.6
Sumatriptan Succinate	61	12.0	12.0
Rizatriptan Benzoate	23	11.2	11.2
Esomeprazole Magnesium	459	10.7	10.7
Doxazosin	58	10.3	10.3
Eptinezumab-Jjmr	19	10.3	10.3
Insulin Glargine-Yfgn	45	10.2	10.2
Simvastatin	463	10.1	10.1
Docusate Sodium 100Mg	47	9.7	9.8
Rimegepant Sulfate	23	9.0	9.0
Butalbital, Acetaminophen, And Caffeine	19	8.8	8.8
Sumatriptan	67	8.8	8.8
Fluticasone Propionate Nasal	51	8.3	8.4
Doxazosin Mesylate	60	8.3	8.3
Levothyroxine Sodium	474	8.2	8.2
Doxepin Hydrochloride	21	8.2	8.2
Botulinum Toxin Type A	20	7.9	8.0
Onabotulinumtoxina	121	7.9	7.9
Omeprazole	495	7.8	7.9
Etonogestrel And Ethinyl Estradiol	35	7.8	7.8
Doxepin	15	7.3	7.3
Sildenafil Powder,	51	7.1	7.1
Abaloparatide	42	7.1	7.1
Omeprazole Magnesium	528	6.5	6.5
Lactulose	49	6.3	6.3
Nitroglycerin	65	6.0	6.0
Citalopram Hydrobromide	128	6.0	6.0
Warfarin Sodium	55	5.9	5.9
Sildenafil	68	5.8	5.8
Citalopram	152	5.6	5.6
Senna Leaf	25	5.3	5.3
Cefuroxime	12	5.2	5.2
Meclizine Hcl 12.5Mg	14	5.1	5.1
Meclizine Hcl 25Mg	14	5.1	5.1
Meclizine Hcl 12.5 Mg	14	5.1	5.1
Meclizine Hcl 25 Mg	14	5.1	5.1
Losartan Potassium	80	5.1	5.1
Carisoprodol	19	4.9	4.9
Vibegron	8	4.9	4.9
Galcanezumab-Gnlm	30	4.7	4.7
Docusate Sodium	54	4.6	4.6
Thyroid, Porcine	10	4.6	4.6
Sennosides 8.6 Mg Tablets	19	4.5	4.5
Senna	19	4.4	4.4
Indapamide	16	4.4	4.4
Vortioxetine	15	4.3	4.3
Loratadine And Pseudoephedrine Sulfate	7	4.3	4.3
Agalsidase Beta	8	4.3	4.3
Ramipril	105	4.2	4.2
Niacin	10	4.2	4.2
Meclizine	14	4.2	4.2
Acetylcysteine	8	4.2	4.2
Magnesium	66	4.0	4.0
Timolol Maleate	8	4.0	4.0
Topiramate	74	3.9	4.0
Fremanezumab-Vfrm	9	3.9	3.9
Cefazolin	7	3.8	3.8
Meclizine Hydrochloride	15	3.8	3.8
Venlafaxine	54	3.7	3.7
Dextrose	10	3.7	3.7
Raloxifene Hydrochloride	11	3.7	3.7
Duloxetine	52	3.7	3.7
Ibuprofen Sodium	32	3.7	3.7
Dextrose Monohydrate	10	3.7	3.7
Erenumab-Aooe	41	3.7	3.7
Naltrexone	23	3.7	3.7
Sitagliptin	53	3.6	3.6
Diclofenac Potassium	8	3.6	3.6
Sennosides	22	3.6	3.6
Ibuprofen Tablets, Coated	31	3.6	3.6
Buspirone Hydrochloride	8	3.6	3.6
Extended Phenytoin Sodium	12	3.5	3.5
Acetaminophen, Aspirin (Nsaid) And Caffeine	12	3.5	3.5
Spironolactone	97	3.4	3.4
Lumacaftor And Ivacaftor	6	3.4	3.4
Loratadine Oral	34	3.4	3.4
Propranolol Hydrochloride	49	3.4	3.4
Pitavastatin Calcium	7	3.4	3.4
Fluticasone Propionate	87	3.3	3.3
Azelastine	12	3.3	3.3
Duloxetine Hydrochloride	123	3.3	3.3
Avapritinib	8	3.2	3.2
Rosuvastatin	131	3.2	3.2
Fingolimod Hcl	56	3.2	3.2
Vilazodone Hydrochloride	6	3.2	3.2
Carboxymethylcellulose Sodium	6	3.1	3.1
Sildenafil Citrate	80	3.1	3.1
Bupropion	28	3.1	3.1
Estradiol Gel 0.1%	28	3.1	3.1
Estradiol Transdermal	28	3.1	3.1
Acetaminophen, Aspirin, And Caffeine	13	3.0	3.0
Olanzapine	63	2.9	2.9
Niraparib	13	2.9	2.9
Loratadine	62	2.9	2.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	5	2.9	2.9
Lurasidone Hydrochloride	12	2.8	2.8
Sodium Oxybate	36	2.7	2.7
Loratadine Tablet	28	2.6	2.6
Fexofenadine Hydrochloride	11	2.5	2.5
Selexipag	13	2.5	2.5
Pegvaliase-Pqpz	4	2.4	2.4
Desvenlafaxine Succinate	13	2.4	2.4
Diclofenac Potassium, Film Coated	4	2.3	2.3
Diclofenac Potassium Tablets	4	2.3	2.3
Desoximetasone	9	2.3	2.3
Lisdexamfetamine Dimesylate	15	2.2	2.2
Ofatumumab	15	2.2	2.2
Nintedanib	14	2.2	2.2
Atomoxetine Hydrochloride	10	2.1	2.1
Diroximel Fumarate	5	2.1	2.1
Asfotase Alfa	4	2.0	2.0
Suvorexant	5	1.9	1.9
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.9	1.9
Dabigatran Etexilate	28	1.8	1.8
Treprostinil	45	1.8	1.8
Conjugated Estrogens And Medroxyprogesterone Acetate	8	1.7	1.7
Elexacaftor, Tezacaftor, And Ivacaftor	4	1.6	1.6
Orlistat	8	1.5	1.5
Brexpiprazole	5	1.5	1.5
Drospirenone And Ethinyl Estradiol	13	1.4	1.4
Teriflunomide	13	1.4	1.4
Varenicline Tartrate	22	1.4	1.4
Isotretinoin	13	1.3	1.3
Dimethyl Fumarate	32	1.3	1.3
Ranitidine Hydrochloride	14	1.3	1.3
Lifitegrast	4	1.2	1.2
Velpatasvir And Sofosbuvir	3	1.1	1.1
Ambrisentan	29	1.1	1.1
Minoxidil	10	1.1	1.1
Relugolix	5	1.0	1.0
Droxidopa	4	0.9	0.9
Levonorgestrel	36	0.9	0.9
Nirmatrelvir And Ritonavir	9	0.8	0.8
Tirzepatide	23	0.7	0.7
Pimavanserin Tartrate	6	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.