OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Tizanidine Hydrochloride

1,148 flagged reaction(s) · 89,434 total co-reports · max PRR 37.1
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Myofascial Pain Syndrome 22 37.1 37.1 signal
2 Lumbar Radiculopathy 29 29.7 29.7 signal
3 Cervical Radiculopathy 17 28.3 28.3 signal
4 Chronic Kidney Disease-mineral And Bone Disorder 23 25.5 25.5 signal
5 Infusion Site Discharge 33 22.9 23.0 signal
6 Infusion Site Bruising 31 17.2 17.3 signal
7 Neurogenic Bladder 29 16.2 16.2 signal
8 Obstructive Sleep Apnoea Syndrome 19 16.1 16.1 signal
9 Pre-existing Condition Improved 85 15.9 16.0 signal
10 Secondary Progressive Multiple Sclerosis 25 15.6 15.6 signal
11 Product Administration Interrupted 94 14.5 14.5 signal
12 Complex Regional Pain Syndrome 18 14.3 14.3 signal
13 Infusion Site Pruritus 36 13.6 13.6 signal
14 Paraplegia 31 12.7 12.7 signal
15 Hyperparathyroidism Secondary 27 12.6 12.6 signal
16 Haemorrhagic Diathesis 38 12.5 12.6 signal
17 Nephrogenic Anaemia 49 12.4 12.4 signal
18 Muscle Spasticity 128 12.2 12.2 signal
19 Bladder Spasm 19 12.0 12.0 signal
20 Drug Screen Negative 18 12.0 12.0 signal
21 Cervical Spinal Stenosis 17 11.6 11.6 signal
22 Pneumonia Aspiration 239 11.3 11.4 signal
23 Infusion Site Haemorrhage 31 11.3 11.3 signal
24 Arthritis Infective 43 10.9 10.9 signal
25 Dysphoria 47 10.9 10.9 signal
26 Chronic Inflammatory Demyelinating Polyradiculoneuropathy 13 10.8 10.8 signal
27 Spinal Fusion Surgery 36 10.5 10.6 signal
28 Intervertebral Disc Degeneration 83 10.5 10.5 signal
29 Cartilage Injury 22 10.5 10.5 signal
30 Cystitis Interstitial 14 10.3 10.3 signal
31 Lumbar Spinal Stenosis 25 10.0 10.0 signal
32 Essential Hypertension 22 10.0 10.0 signal
33 Infusion Site Swelling 52 9.9 10.0 signal
34 Intervertebral Disc Disorder 36 9.9 9.9 signal
35 Spinal Osteoarthritis 73 9.7 9.8 signal
36 Acute Sinusitis 14 9.6 9.6 signal
37 Narcolepsy 15 9.3 9.4 signal
38 Multiple Allergies 62 9.3 9.3 signal
39 Facial Bones Fracture 28 9.0 9.0 signal
40 Fibula Fracture 22 8.9 8.9 signal
41 Post-traumatic Stress Disorder 50 8.7 8.8 signal
42 Anxiety Disorder 25 8.7 8.8 signal
43 Impaired Gastric Emptying 94 8.7 8.7 signal
44 Appetite Disorder 48 8.7 8.7 signal
45 Device Infusion Issue 18 8.6 8.6 signal
46 Intervertebral Disc Protrusion 160 8.6 8.6 signal
47 Patella Fracture 17 8.6 8.6 signal
48 Radiculopathy 19 8.5 8.5 signal
49 Urinary Tract Infection Bacterial 18 8.4 8.4 signal
50 Drug Tolerance 36 8.3 8.3 signal
51 Neck Surgery 16 8.2 8.2 signal
52 Seasonal Allergy 98 8.2 8.2 signal
53 Fibromyalgia 167 8.1 8.1 signal
54 Skin Warm 40 8.1 8.1 signal
55 Diabetic Neuropathy 34 8.0 8.0 signal
56 Sleep Apnoea Syndrome 125 7.7 7.7 signal
57 Multiple Sclerosis 311 7.6 7.7 signal
58 Tenderness 66 7.4 7.4 signal
59 Infusion Site Erythema 52 7.4 7.4 signal
60 Infusion Site Pain 77 7.1 7.1 signal
61 Ankle Fracture 92 7.0 7.0 signal
62 Multiple Sclerosis Relapse 404 6.9 7.0 signal
63 Snoring 22 6.8 6.8 signal
64 Neck Injury 17 6.8 6.8 signal
65 Metabolic Encephalopathy 17 6.6 6.7 signal
66 Decubitus Ulcer 46 6.6 6.6 signal
67 Rhinitis Allergic 25 6.6 6.6 signal
68 Chronic Sinusitis 21 6.6 6.6 signal
69 Decreased Interest 33 6.6 6.6 signal
70 Breakthrough Pain 13 6.5 6.5 signal
71 Vitamin D Deficiency 54 6.5 6.5 signal
72 Gastrooesophageal Reflux Disease 443 6.5 6.6 signal
73 Peroneal Nerve Palsy 31 6.4 6.4 signal
74 Back Disorder 89 6.4 6.4 signal
75 Ligament Rupture 24 6.4 6.4 signal
76 Respiratory Rate Decreased 17 6.3 6.3 signal
77 Inadequate Analgesia 46 6.3 6.3 signal
78 Major Depression 39 6.2 6.3 signal
79 Scoliosis 33 6.2 6.2 signal
80 Personality Disorder 14 6.2 6.2 signal
81 Concussion 41 6.2 6.2 signal
82 Bronchitis Chronic 13 6.2 6.2 signal
83 Coma 252 6.2 6.3 signal
84 Oesophageal Stenosis 15 6.2 6.2 signal
85 Trigeminal Neuralgia 21 6.1 6.1 signal
86 Nerve Compression 48 6.1 6.1 signal
87 Enuresis 21 6.1 6.1 signal
88 Ligament Sprain 51 6.1 6.1 signal
89 Infusion Site Reaction 15 6.0 6.1 signal
90 Dermatitis Contact 58 6.0 6.0 signal
91 Spinal Column Stenosis 24 5.9 5.9 signal
92 Obstruction 20 5.9 5.9 signal
93 Neck Pain 277 5.8 5.9 signal
94 Neuralgia 120 5.8 5.8 signal
95 Ear Pain 96 5.8 5.8 signal
96 Glucose Tolerance Impaired 29 5.8 5.8 signal
97 Areflexia 13 5.7 5.7 signal
98 Restless Legs Syndrome 88 5.7 5.7 signal
99 End Stage Renal Disease 89 5.7 5.7 signal
100 Bladder Disorder 48 5.7 5.7 signal
101 Thinking Abnormal 90 5.6 5.7 signal
102 Autoimmune Thyroiditis 18 5.6 5.6 signal
103 Insurance Issue 71 5.6 5.6 signal
104 Spinal Disorder 45 5.6 5.6 signal
105 Incorrect Drug Administration Rate 20 5.5 5.5 signal
106 Non-cardiac Chest Pain 15 5.5 5.5 signal
107 Spinal Operation 57 5.5 5.5 signal
108 Initial Insomnia 48 5.5 5.5 signal
109 Somnambulism 31 5.5 5.5 signal
110 Temperature Intolerance 48 5.5 5.5 signal
111 Paranasal Sinus Hypersecretion 18 5.5 5.5 signal
112 Hyperlipidaemia 56 5.5 5.5 signal
113 Foot Fracture 88 5.4 5.4 signal
114 Back Injury 50 5.4 5.4 signal
115 Difficulty In Walking 16 5.4 5.4 signal
116 Rotator Cuff Syndrome 59 5.4 5.4 signal
117 Migraine 433 5.3 5.5 signal
118 Lyme Disease 15 5.3 5.3 signal
119 Hand Fracture 32 5.3 5.3 signal
120 Bursitis 53 5.1 5.2 signal
121 Osteoarthritis 184 5.1 5.1 signal
122 Muscle Tightness 70 5.1 5.1 signal
123 Formication 30 5.0 5.0 signal
124 Sinus Disorder 85 5.0 5.0 signal
125 Carpal Tunnel Syndrome 60 5.0 5.0 signal
126 Intracranial Aneurysm 17 5.0 5.0 signal
127 Photophobia 79 5.0 5.0 signal
128 Urinary Tract Disorder 19 4.9 4.9 signal
129 Urinary Incontinence 125 4.9 5.0 signal
130 Fibrin D Dimer Increased 15 4.9 4.9 signal
131 Multiple Drug Overdose 21 4.9 4.9 signal
132 Nuclear Magnetic Resonance Imaging Abnormal 14 4.9 4.9 signal
133 Tooth Abscess 42 4.8 4.8 signal
134 Faecal Incontinence 20 4.8 4.8 signal
135 Cystitis 131 4.8 4.8 signal
136 Sensory Loss 33 4.8 4.8 signal
137 Vitamin D Decreased 35 4.8 4.8 signal
138 Foot Operation 20 4.8 4.8 signal
139 Skin Abrasion 19 4.8 4.8 signal
140 Lymphoedema 28 4.7 4.8 signal
141 Hysterectomy 35 4.7 4.8 signal
142 Blood Magnesium Decreased 35 4.7 4.8 signal
143 Joint Effusion 28 4.7 4.7 signal
144 Chronic Kidney Disease 309 4.7 4.8 signal
145 Atelectasis 39 4.7 4.7 signal
146 Drug Abuser 25 4.7 4.7 signal
147 Hyperreflexia 14 4.7 4.7 signal
148 Haemoglobin Increased 18 4.7 4.7 signal
149 Paranasal Sinus Discomfort 15 4.7 4.7 signal
150 Vitamin B12 Deficiency 16 4.7 4.7 signal
151 Skin Laceration 43 4.7 4.7 signal
152 Kidney Infection 78 4.7 4.7 signal
153 Hypervolaemia 19 4.6 4.6 signal
154 Thyroid Mass 15 4.6 4.6 signal
155 Arthropod Bite 29 4.6 4.6 signal
156 Exostosis 36 4.6 4.6 signal
157 Sinusitis 404 4.6 4.7 signal
158 Spondylitis 14 4.5 4.5 signal
159 Clostridial Infection 13 4.5 4.5 signal
160 Blood Potassium Decreased 114 4.4 4.5 signal
161 Bronchitis 281 4.4 4.5 signal
162 Dysarthria 142 4.4 4.4 signal
163 Escherichia Urinary Tract Infection 16 4.4 4.4 signal
164 Depression Suicidal 13 4.4 4.4 signal
165 Weight Fluctuation 39 4.4 4.4 signal
166 Overweight 20 4.4 4.4 signal
167 Sciatica 59 4.4 4.4 signal
168 Sinus Bradycardia 36 4.4 4.4 signal
169 Micturition Urgency 42 4.3 4.3 signal
170 Hiatus Hernia 48 4.3 4.3 signal
171 Post Procedural Infection 30 4.3 4.3 signal
172 Urinary Tract Infection 624 4.3 4.4 signal
173 Peripheral Vascular Disorder 19 4.3 4.3 signal
174 Loss Of Control Of Legs 14 4.3 4.3 signal
175 Thermal Burn 26 4.3 4.3 signal
176 Pancreatic Disorder 18 4.3 4.3 signal
177 Gastroenteritis Viral 66 4.3 4.3 signal
178 Walking Aid User 24 4.2 4.2 signal
179 Dental Caries 40 4.2 4.2 signal
180 Central Nervous System Lesion 50 4.2 4.2 signal
181 Product Distribution Issue 32 4.2 4.2 signal
182 Incontinence 38 4.2 4.2 signal
183 Obesity 57 4.2 4.2 signal
184 Hallucinations, Mixed 15 4.2 4.2 signal
185 Road Traffic Accident 149 4.2 4.2 signal
186 Drug Screen Positive 28 4.2 4.2 signal
187 Infusion Site Extravasation 22 4.1 4.1 signal
188 Oral Pain 79 4.1 4.1 signal
189 Nasal Dryness 22 4.1 4.1 signal
190 Ovarian Cyst 35 4.1 4.1 signal
191 Bipolar Disorder 38 4.1 4.1 signal
192 Diverticulum 25 4.1 4.1 signal
193 Upper Respiratory Tract Infection 160 4.1 4.1 signal
194 Hypoaesthesia 519 4.1 4.1 signal
195 Diverticulum Intestinal 15 4.0 4.0 signal
196 Spinal Stenosis 14 4.0 4.0 signal
197 Flank Pain 32 4.0 4.0 signal
198 Dysphemia 15 4.0 4.0 signal
199 Spinal Pain 40 4.0 4.0 signal
200 Joint Injury 73 4.0 4.0 signal
201 Streptococcal Infection 19 4.0 4.0 signal
202 Nerve Injury 38 4.0 4.0 signal
203 Tibia Fracture 16 4.0 4.0 signal
204 Incoherent 22 4.0 4.0 signal
205 Clavicle Fracture 13 4.0 4.0 signal
206 Mental Status Changes 94 4.0 4.0 signal
207 Depression 770 3.9 4.1 signal
208 Muscle Strain 29 3.9 3.9 signal
209 Muscle Spasms 616 3.9 4.0 signal
210 Diplopia 87 3.9 3.9 signal
211 Middle Insomnia 62 3.9 3.9 signal
212 Body Height Decreased 36 3.9 3.9 signal
213 Stress Fracture 18 3.9 3.9 signal
214 Lower Limb Fracture 63 3.9 3.9 signal
215 Somnolence 662 3.9 4.0 signal
216 Ear Infection 87 3.8 3.8 signal
217 Uterine Leiomyoma 24 3.8 3.8 signal
218 Balance Disorder 283 3.8 3.9 signal
219 Sedation 85 3.8 3.8 signal
220 Urosepsis 30 3.8 3.8 signal
221 Meniscus Injury 20 3.8 3.8 signal
222 Hypokinesia 47 3.8 3.8 signal
223 Head Injury 102 3.8 3.8 signal
224 Synovial Cyst 15 3.8 3.8 signal
225 Joint Dislocation 34 3.8 3.8 signal
226 Rhinitis 26 3.8 3.8 signal
227 Feeling Drunk 24 3.8 3.8 signal
228 Limb Injury 87 3.8 3.8 signal
229 Panic Attack 117 3.8 3.8 signal
230 Influenza Like Illness 262 3.7 3.7 signal
231 Product Dose Omission In Error 85 3.7 3.7 signal
232 Back Pain 735 3.7 3.8 signal
233 Skin Infection 35 3.7 3.7 signal
234 Tooth Infection 41 3.6 3.6 signal
235 Vascular Device Infection 14 3.6 3.6 signal
236 Fall 1,030 3.6 3.8 signal
237 Obsessive-compulsive Disorder 25 3.6 3.6 signal
238 Cholecystitis Chronic 21 3.6 3.6 signal
239 Gait Disturbance 590 3.6 3.7 signal
240 Abdominal Hernia 14 3.6 3.6 signal
241 Motor Dysfunction 31 3.6 3.6 signal
242 Hepatic Steatosis 57 3.6 3.6 signal
243 Surgery 177 3.6 3.6 signal
244 Laceration 29 3.6 3.6 signal
245 Increased Tendency To Bruise 28 3.6 3.6 signal
246 Activities Of Daily Living Impaired 61 3.6 3.6 signal
247 Tricuspid Valve Incompetence 24 3.6 3.6 signal
248 Energy Increased 18 3.5 3.5 signal
249 Sinus Congestion 41 3.5 3.5 signal
250 Convulsion 175 3.5 3.6 signal
251 Nephrolithiasis 138 3.5 3.5 signal
252 Post Procedural Complication 58 3.5 3.5 signal
253 Sinus Headache 18 3.5 3.5 signal
254 Dysstasia 88 3.5 3.5 signal
255 Wrist Fracture 36 3.5 3.5 signal
256 Candida Infection 50 3.5 3.5 signal
257 Tooth Fracture 33 3.5 3.5 signal
258 Coordination Abnormal 42 3.5 3.5 signal
259 Tendon Rupture 37 3.5 3.5 signal
260 Orthostatic Hypotension 52 3.5 3.5 signal
261 Musculoskeletal Chest Pain 46 3.5 3.5 signal
262 Hypersomnia 85 3.5 3.5 signal
263 Pelvic Fracture 23 3.5 3.5 signal
264 Respiratory Tract Congestion 47 3.5 3.5 signal
265 Osteopenia 45 3.4 3.5 signal
266 Illness 296 3.4 3.5 signal
267 Herpes Virus Infection 17 3.4 3.4 signal
268 Hemiparesis 50 3.4 3.4 signal
269 Upper-airway Cough Syndrome 24 3.4 3.4 signal
270 Social Avoidant Behaviour 17 3.4 3.4 signal
271 Catheterisation Cardiac 13 3.4 3.4 signal
272 Contusion 281 3.4 3.5 signal
273 Facial Pain 26 3.4 3.4 signal
274 Withdrawal Syndrome 123 3.4 3.4 signal
275 Progressive Multifocal Leukoencephalopathy 24 3.4 3.4 signal
276 Hypovolaemia 17 3.4 3.4 signal
277 Poor Venous Access 30 3.4 3.4 signal
278 Memory Impairment 399 3.4 3.4 signal
279 Paranoia 50 3.4 3.4 signal
280 Malnutrition 32 3.4 3.4 signal
281 Abasia 72 3.4 3.4 signal
282 Dysgraphia 19 3.4 3.4 signal
283 Fungal Infection 95 3.3 3.3 signal
284 Ataxia 34 3.3 3.3 signal
285 Cardiomegaly 35 3.3 3.3 signal
286 Abdominal Tenderness 14 3.3 3.3 signal
287 Respiratory Tract Infection 73 3.3 3.3 signal
288 Pharyngitis 35 3.3 3.3 signal
289 Hallucination 210 3.3 3.3 signal
290 Pharyngolaryngeal Pain 15 3.3 3.3 signal
291 Hypertonia 16 3.3 3.3 signal
292 Gastritis 73 3.2 3.3 signal
293 Loss Of Consciousness 356 3.2 3.3 signal
294 Blood Pressure Abnormal 55 3.2 3.3 signal
295 Coronary Artery Stenosis 14 3.2 3.2 signal
296 Pharyngitis Streptococcal 30 3.2 3.2 signal
297 Musculoskeletal Stiffness 242 3.2 3.3 signal
298 Sluggishness 28 3.2 3.2 signal
299 Bedridden 36 3.2 3.2 signal
300 Optic Neuritis 25 3.2 3.2 signal
301 Muscular Weakness 311 3.2 3.2 signal
302 Sneezing 61 3.2 3.2 signal
303 Endometriosis 13 3.2 3.2 signal
304 Osteoporosis 112 3.2 3.2 signal
305 Anhedonia 72 3.2 3.2 signal
306 Wrong Technique In Drug Usage Process 100 3.2 3.2 signal
307 Muscle Disorder 22 3.2 3.2 signal
308 Benign Prostatic Hyperplasia 14 3.2 3.2 signal
309 Abnormal Dreams 75 3.2 3.2 signal
310 Malabsorption 14 3.2 3.2 signal
311 Anal Incontinence 24 3.2 3.2 signal
312 Therapeutic Response Unexpected 121 3.1 3.2 signal
313 Limb Discomfort 83 3.1 3.1 signal
314 Scar 46 3.1 3.1 signal
315 Brain Fog 39 3.1 3.1 signal
316 Eye Pain 147 3.1 3.1 signal
317 Amnesia 173 3.1 3.1 signal
318 Cardiac Murmur 23 3.1 3.1 signal
319 Oedema 143 3.1 3.1 signal
320 Impaired Driving Ability 30 3.1 3.1 signal
321 Herpes Simplex 17 3.1 3.1 signal
322 Scratch 27 3.0 3.1 signal
323 Cellulitis 131 3.0 3.1 signal
324 Immune System Disorder 34 3.0 3.0 signal
325 Visual Disturbance 15 3.0 3.0 signal
326 Hip Arthroplasty 39 3.0 3.0 signal
327 Blood Pressure Decreased 170 3.0 3.0 signal
328 Foreign Body Sensation In Eyes 16 3.0 3.0 signal
329 Musculoskeletal Pain 135 3.0 3.0 signal
330 Arthritis 201 3.0 3.0 signal
331 Lymphocyte Count Decreased 45 3.0 3.0 signal
332 Sensory Disturbance 41 3.0 3.0 signal
333 Knee Arthroplasty 53 3.0 3.0 signal
334 Retching 54 3.0 3.0 signal
335 Hyperaesthesia 21 3.0 3.0 signal
336 Transient Ischaemic Attack 86 3.0 3.0 signal
337 Electrocardiogram Abnormal 20 3.0 3.0 signal
338 Rib Fracture 52 3.0 3.0 signal
339 Crying 92 2.9 3.0 signal
340 Heart Rate Decreased 89 2.9 3.0 signal
341 Flushing 257 2.9 3.0 signal
342 Gallbladder Disorder 45 2.9 2.9 signal
343 Renal Cyst 20 2.9 2.9 signal
344 Chronic Obstructive Pulmonary Disease 131 2.9 3.0 signal
345 Staphylococcal Infection 83 2.9 2.9 signal
346 Complication Associated With Device 33 2.9 2.9 signal
347 Laryngitis 27 2.9 2.9 signal
348 Eye Movement Disorder 17 2.9 2.9 signal
349 Cognitive Disorder 115 2.9 2.9 signal
350 Dry Mouth 200 2.9 2.9 signal
351 Viral Infection 82 2.9 2.9 signal
352 Cholecystectomy 28 2.9 2.9 signal
353 Blood Iron Decreased 29 2.9 2.9 signal
354 Chills 288 2.9 2.9 signal
355 Renal Tubular Necrosis 24 2.9 2.9 signal
356 Tremor 404 2.8 2.9 signal
357 Anxiety 689 2.8 2.9 signal
358 Cyst 30 2.8 2.8 signal
359 Burning Sensation 169 2.8 2.8 signal
360 Influenza 269 2.8 2.8 signal
361 Haemorrhoids 47 2.8 2.8 signal
362 Pharyngeal Swelling 23 2.8 2.8 signal
363 Economic Problem 37 2.8 2.8 signal
364 Blood Calcium Increased 21 2.8 2.8 signal
365 Night Sweats 77 2.8 2.8 signal
366 Poor Quality Sleep 51 2.8 2.8 signal
367 Insomnia 635 2.8 2.8 signal
368 Drug Withdrawal Syndrome 211 2.8 2.8 signal
369 Intentional Dose Omission 65 2.8 2.8 signal
370 Disability 47 2.8 2.8 signal
371 Asthma 266 2.8 2.8 signal
372 Stress 170 2.8 2.8 signal
373 Pain 1,451 2.8 2.9 signal
374 Pulmonary Mass 35 2.8 2.8 signal
375 Personality Change 22 2.7 2.8 signal
376 Accident 28 2.7 2.8 signal
377 Oral Mucosal Blistering 15 2.7 2.7 signal
378 Blood Sodium Decreased 44 2.7 2.7 signal
379 Dysphagia 221 2.7 2.8 signal
380 Sputum Discoloured 22 2.7 2.7 signal
381 Gait Inability 77 2.7 2.7 signal
382 Hallucination, Auditory 37 2.7 2.7 signal
383 Covid-19 410 2.7 2.7 signal
384 Blood Cholesterol Increased 108 2.7 2.7 signal
385 Hypophosphataemia 17 2.7 2.7 signal
386 Skin Disorder 77 2.7 2.7 signal
387 Hunger 31 2.7 2.7 signal
388 Blood Calcium Decreased 26 2.7 2.7 signal
389 Speech Disorder 120 2.7 2.7 signal
390 Iron Deficiency Anaemia 21 2.7 2.7 signal
391 Small Intestinal Obstruction 28 2.7 2.7 signal
392 Prescribed Overdose 44 2.7 2.7 signal
393 Localised Infection 55 2.7 2.7 signal
394 Loss Of Personal Independence In Daily Activities 108 2.7 2.7 signal
395 Anger 77 2.6 2.7 signal
396 Cold Sweat 40 2.6 2.7 signal
397 Knee Operation 22 2.6 2.6 signal
398 Movement Disorder 73 2.6 2.7 signal
399 Local Swelling 40 2.6 2.6 signal
400 Dysuria 83 2.6 2.6 signal
401 Headache 1,408 2.6 2.8 signal
402 Chest Pain 417 2.6 2.7 signal
403 Constipation 486 2.6 2.7 signal
404 Blood Pressure Increased 343 2.6 2.6 signal
405 Bowel Movement Irregularity 17 2.6 2.6 signal
406 Nocturia 27 2.6 2.6 signal
407 Postoperative Wound Infection 15 2.6 2.6 signal
408 Drug Hypersensitivity 431 2.6 2.6 signal
409 Skin Haemorrhage 32 2.6 2.6 signal
410 Intestinal Obstruction 83 2.6 2.6 signal
411 Completed Suicide 186 2.6 2.6 signal
412 Hyperhidrosis 285 2.6 2.6 signal
413 Musculoskeletal Discomfort 38 2.6 2.6 signal
414 Hypertension 468 2.6 2.6 signal
415 Paraesthesia 348 2.6 2.6 signal
416 Thyroid Disorder 34 2.6 2.6 signal
417 Hypothyroidism 70 2.6 2.6 signal
418 Blister 123 2.6 2.6 signal
419 Hypercholesterolaemia 21 2.6 2.6 signal
420 Hypotonia 22 2.6 2.6 signal
421 Suicidal Ideation 201 2.6 2.6 signal
422 Type 2 Diabetes Mellitus 74 2.6 2.6 signal
423 Disorientation 87 2.6 2.6 signal
424 Pneumonia Bacterial 20 2.6 2.6 signal
425 Dehydration 291 2.5 2.6 signal
426 Nasal Congestion 127 2.5 2.5 signal
427 Tooth Extraction 27 2.5 2.5 signal
428 Large Intestine Polyp 15 2.5 2.5 signal
429 Muscle Twitching 50 2.5 2.5 signal
430 Cardiac Flutter 14 2.5 2.5 signal
431 Galactorrhoea 14 2.5 2.5 signal
432 Pain In Extremity 637 2.5 2.6 signal
433 Groin Pain 19 2.5 2.5 signal
434 Ear Discomfort 22 2.5 2.5 signal
435 Decreased Activity 23 2.5 2.5 signal
436 Dyskinesia 87 2.5 2.5 signal
437 Injection Site Urticaria 52 2.5 2.5 signal
438 Serotonin Syndrome 41 2.5 2.5 signal
439 Polyp 14 2.5 2.5 signal
440 Euphoric Mood 22 2.5 2.5 signal
441 Angina Unstable 14 2.5 2.5 signal
442 Thirst 38 2.5 2.5 signal
443 Wheezing 126 2.5 2.5 signal
444 Drug Effect Less Than Expected 30 2.5 2.5 signal
445 Gastrointestinal Infection 19 2.5 2.5 signal
446 Hepatomegaly 21 2.5 2.5 signal
447 Disturbance In Attention 115 2.5 2.5 signal
448 Aspiration 23 2.5 2.5 signal
449 Arthropathy 118 2.5 2.5 signal
450 Aphasia 64 2.5 2.5 signal
451 Mobility Decreased 151 2.5 2.5 signal
452 Lethargy 121 2.5 2.5 signal
453 Osteomyelitis 38 2.5 2.5 signal
454 Coronary Artery Disease 64 2.5 2.5 signal
455 Product Dose Omission Issue 597 2.4 2.5 signal
456 Joint Range Of Motion Decreased 28 2.4 2.4 signal
457 Neuropathy Peripheral 198 2.4 2.5 signal
458 Autoimmune Disorder 20 2.4 2.4 signal
459 Pollakiuria 87 2.4 2.4 signal
460 Colitis Ischaemic 14 2.4 2.4 signal
461 Breast Mass 14 2.4 2.4 signal
462 Aphonia 29 2.4 2.4 signal
463 Respiratory Syncytial Virus Infection 18 2.4 2.4 signal
464 Escherichia Infection 17 2.4 2.4 signal
465 Low Density Lipoprotein Increased 16 2.4 2.4 signal
466 Ulcer 33 2.4 2.4 signal
467 Dry Throat 21 2.4 2.4 signal
468 Affect Lability 20 2.4 2.4 signal
469 Vertigo 126 2.4 2.4 signal
470 Diverticulitis 57 2.4 2.4 signal
471 Irritable Bowel Syndrome 44 2.4 2.4 signal
472 Weight Decreased 573 2.4 2.4 signal
473 Wound 57 2.4 2.4 signal
474 Nightmare 71 2.4 2.4 signal
475 Feeling Jittery 39 2.4 2.4 signal
476 Feeling Abnormal 491 2.4 2.4 signal
477 Drooling 14 2.4 2.4 signal
478 Asthenia 765 2.4 2.4 signal
479 Thrombosis 164 2.4 2.4 signal
480 Renal Injury 61 2.4 2.4 signal
481 Peripheral Coldness 28 2.4 2.4 signal
482 Psychiatric Symptom 15 2.4 2.4 signal
483 Vision Blurred 277 2.4 2.4 signal
484 Renal Failure 271 2.4 2.4 signal
485 Procedural Pain 56 2.4 2.4 signal
486 Wound Infection 22 2.4 2.4 signal
487 Dry Eye 98 2.4 2.4 signal
488 Unresponsive To Stimuli 52 2.4 2.4 signal
489 Paralysis 29 2.4 2.4 signal
490 Rhinorrhoea 130 2.4 2.4 signal
491 Pulmonary Thrombosis 22 2.4 2.4 signal
492 Oral Discomfort 28 2.4 2.4 signal
493 Pain In Jaw 57 2.3 2.4 signal
494 Gastrointestinal Pain 22 2.3 2.3 signal
495 Spinal Fracture 40 2.3 2.3 signal
496 Deep Vein Thrombosis 131 2.3 2.4 signal
497 Haematocrit Decreased 40 2.3 2.3 signal
498 Hereditary Angioedema 21 2.3 2.3 signal
499 Upper Limb Fracture 40 2.3 2.3 signal
500 Application Site Vesicles 13 2.3 2.3 signal
501 Tendonitis 31 2.3 2.3 signal
502 Bacterial Infection 37 2.3 2.3 signal
503 Toothache 36 2.3 2.3 signal
504 Muscle Atrophy 25 2.3 2.3 signal
505 Renal Pain 21 2.3 2.3 signal
506 Pharyngeal Oedema 31 2.3 2.3 signal
507 Food Allergy 15 2.3 2.3 signal
508 Hypotension 397 2.3 2.3 signal
509 Foot Deformity 22 2.3 2.3 signal
510 Joint Stiffness 52 2.3 2.3 signal
511 Sleep Disorder 138 2.3 2.3 signal
512 Feeling Cold 55 2.3 2.3 signal
513 Feeling Hot 121 2.3 2.3 signal
514 Tooth Disorder 44 2.3 2.3 signal
515 Fluid Retention 100 2.3 2.3 signal
516 Herpes Zoster 113 2.3 2.3 signal
517 Eye Infection 22 2.3 2.3 signal
518 Weight Increased 436 2.3 2.3 signal
519 Fatigue 1,518 2.3 2.4 signal
520 Body Temperature Increased 40 2.3 2.3 signal
521 Arthralgia 809 2.3 2.3 signal
522 Visual Impairment 240 2.3 2.3 signal
523 Procedural Complication 15 2.3 2.3 signal
524 Respiratory Arrest 54 2.3 2.3 signal
525 Scab 22 2.3 2.3 signal
526 Ocular Discomfort 21 2.3 2.3 signal
527 Musculoskeletal Disorder 37 2.3 2.3 signal
528 Oropharyngeal Pain 179 2.3 2.3 signal
529 Myalgia 328 2.3 2.3 signal
530 Gastroenteritis 28 2.2 2.2 signal
531 Abnormal Loss Of Weight 13 2.2 2.2 signal
532 Anorexia 25 2.2 2.2 signal
533 Lung Infiltration 17 2.2 2.2 signal
534 Acute Kidney Injury 290 2.2 2.2 signal
535 Presyncope 46 2.2 2.2 signal
536 Oxygen Saturation Decreased 106 2.2 2.2 signal
537 Pharmaceutical Product Complaint 50 2.2 2.2 signal
538 Dyspnoea Exertional 71 2.2 2.2 signal
539 Cholelithiasis 62 2.2 2.2 signal
540 Pulmonary Congestion 25 2.2 2.2 signal
541 Coronary Artery Occlusion 26 2.2 2.2 signal
542 Clostridium Difficile Colitis 20 2.2 2.2 signal
543 Bradycardia 100 2.2 2.2 signal
544 Acute Respiratory Failure 36 2.2 2.2 signal
545 Emphysema 19 2.2 2.2 signal
546 Bone Pain 110 2.2 2.2 signal
547 Seizure 215 2.2 2.2 signal
548 Eating Disorder 40 2.2 2.2 signal
549 Hot Flush 141 2.2 2.2 signal
550 Pruritus Generalised 41 2.2 2.2 signal
551 Dizziness 926 2.2 2.2 signal
552 Productive Cough 88 2.2 2.2 signal
553 Hallucination, Visual 39 2.2 2.2 signal
554 Parosmia 14 2.2 2.2 signal
555 Mental Impairment 45 2.2 2.2 signal
556 Extrasystoles 13 2.2 2.2 signal
557 Hypoxia 65 2.2 2.2 signal
558 Heart Rate Irregular 42 2.2 2.2 signal
559 Oedema Peripheral 226 2.2 2.2 signal
560 Oral Candidiasis 24 2.2 2.2 signal
561 Immunosuppression 16 2.2 2.2 signal
562 Diabetes Mellitus 141 2.2 2.2 signal
563 Nausea 1,452 2.1 2.3 signal
564 Dyspepsia 180 2.1 2.2 signal
565 Abnormal Faeces 15 2.1 2.1 signal
566 Grip Strength Decreased 16 2.1 2.1 signal
567 Heart Rate Increased 181 2.1 2.1 signal
568 Aortic Aneurysm 14 2.1 2.1 signal
569 Tinnitus 84 2.1 2.1 signal
570 Mood Altered 49 2.1 2.1 signal
571 Pneumonia 582 2.1 2.1 signal
572 Impaired Healing 59 2.1 2.1 signal
573 Irritability 108 2.1 2.1 signal
574 Confusional State 290 2.1 2.1 signal
575 Syncope 179 2.1 2.1 signal
576 Apnoea 14 2.1 2.1 signal
577 Injury 126 2.1 2.1 signal
578 Gastric Disorder 62 2.1 2.1 signal
579 Device Failure 27 2.1 2.1 signal
580 Supraventricular Tachycardia 17 2.1 2.1 signal
581 Drug Administered At Inappropriate Site 19 2.1 2.1 signal
582 Cough 496 2.1 2.1 signal
583 Eyelid Ptosis 18 2.1 2.1 signal
584 Furuncle 14 2.1 2.1 signal
585 Mitral Valve Incompetence 20 2.1 2.1 signal
586 Eye Discharge 18 2.1 2.1 signal
587 Psychotic Disorder 52 2.1 2.1 signal
588 Unevaluable Event 133 2.1 2.1 signal
589 Depressed Level Of Consciousness 69 2.0 2.0 signal
590 Abdominal Discomfort 292 2.0 2.1 signal
591 Peripheral Swelling 268 2.0 2.1 signal
592 Injection Site Irritation 22 2.0 2.0 signal
593 Abdominal Distension 180 2.0 2.0 signal
594 Ventricular Extrasystoles 18 2.0 2.0 signal
595 Abnormal Behaviour 69 2.0 2.0 signal
596 Inability To Afford Medication 17 2.0 2.0 signal
597 White Blood Cell Count Increased 66 2.0 2.0 signal
598 Polyuria 14 2.0 2.0 no signal
599 Feeding Disorder 34 2.0 2.0 no signal
600 Eye Swelling 63 2.0 2.0 no signal
601 Mania 28 2.0 2.0 no signal
602 Throat Tightness 46 2.0 2.0 no signal
603 Lymphadenopathy 60 2.0 2.0 no signal
604 Cholecystitis 20 2.0 2.0 no signal
605 Covid-19 Pneumonia 20 2.0 2.0 no signal
606 Chest Discomfort 171 2.0 2.0 no signal
607 Mental Disorder 73 2.0 2.0 no signal
608 Depressed Mood 88 2.0 2.0 no signal
609 Sleep Disorder Due To A General Medical Condition 27 1.9 2.0 no signal
610 Spinal Compression Fracture 14 1.9 1.9 no signal
611 Dizziness Postural 16 1.9 1.9 no signal
612 Blood Urea Increased 28 1.9 1.9 no signal
613 Clostridium Difficile Infection 36 1.9 1.9 no signal
614 Hypomagnesaemia 23 1.9 1.9 no signal
615 Affective Disorder 13 1.9 1.9 no signal
616 Hypokalaemia 76 1.9 1.9 no signal
617 Vomiting 776 1.9 2.0 no signal
618 Increased Appetite 31 1.9 1.9 no signal
619 Skin Swelling 14 1.9 1.9 no signal
620 Palpitations 192 1.9 1.9 no signal
621 Nasopharyngitis 303 1.9 1.9 no signal
622 Systemic Lupus Erythematosus 58 1.9 1.9 no signal
623 Quality Of Life Decreased 22 1.9 1.9 no signal
624 Blood Triglycerides Increased 29 1.9 1.9 no signal
625 Pulmonary Embolism 156 1.9 1.9 no signal
626 Bone Disorder 30 1.9 1.9 no signal
627 Respiratory Depression 20 1.9 1.9 no signal
628 Gastric Ulcer 31 1.9 1.9 no signal
629 Rheumatoid Arthritis 184 1.9 1.9 no signal
630 Dysphonia 95 1.9 1.9 no signal
631 Cataract 96 1.9 1.9 no signal
632 Skin Lesion 44 1.9 1.9 no signal
633 Hernia 31 1.9 1.9 no signal
634 Incorrect Route Of Product Administration 27 1.9 1.9 no signal
635 Lacrimation Increased 48 1.9 1.9 no signal
636 Swelling 150 1.9 1.9 no signal
637 Therapy Cessation 82 1.9 1.9 no signal
638 Joint Swelling 193 1.9 1.9 no signal
639 Nervousness 84 1.9 1.9 no signal
640 Mood Swings 51 1.9 1.9 no signal
641 Brain Injury 16 1.9 1.9 no signal
642 Arteriosclerosis 15 1.9 1.9 no signal
643 Muscle Rigidity 19 1.9 1.9 no signal
644 Hip Fracture 51 1.9 1.9 no signal
645 Throat Irritation 71 1.9 1.9 no signal
646 Apathy 23 1.8 1.8 no signal
647 Blood Pressure Fluctuation 38 1.8 1.8 no signal
648 Blood Urine Present 30 1.8 1.8 no signal
649 Mass 22 1.8 1.8 no signal
650 Oropharyngeal Discomfort 14 1.8 1.8 no signal
651 Psoriatic Arthropathy 63 1.8 1.8 no signal
652 Condition Aggravated 472 1.8 1.8 no signal
653 Agitation 115 1.8 1.8 no signal
654 Fluid Overload 23 1.8 1.8 no signal
655 Renal Failure Acute 67 1.8 1.8 no signal
656 Dyspnoea 878 1.8 1.9 no signal
657 Sinus Tachycardia 22 1.8 1.8 no signal
658 Injection Site Rash 47 1.8 1.8 no signal
659 Anaphylactic Reaction 85 1.8 1.8 no signal
660 Cardiac Failure Congestive 125 1.8 1.8 no signal
661 Infection 222 1.8 1.8 no signal
662 Therapeutic Response Shortened 49 1.8 1.8 no signal
663 Haematoma 40 1.8 1.8 no signal
664 Secretion Discharge 19 1.8 1.8 no signal
665 Drug Effect Decreased 84 1.8 1.8 no signal
666 Respiratory Disorder 46 1.8 1.8 no signal
667 Angina Pectoris 44 1.8 1.8 no signal
668 Sepsis 170 1.8 1.8 no signal
669 Liver Function Test Abnormal 44 1.8 1.8 no signal
670 Tubulointerstitial Nephritis 28 1.7 1.7 no signal
671 Abdominal Pain Upper 307 1.7 1.8 no signal
672 Nephropathy 14 1.7 1.7 no signal
673 Intentional Product Use Issue 131 1.7 1.7 no signal
674 Abdominal Pain 346 1.7 1.8 no signal
675 Hepatic Enzyme Increased 101 1.7 1.7 no signal
676 Pruritus 561 1.7 1.8 no signal
677 Flatulence 84 1.7 1.7 no signal
678 Suicide Attempt 89 1.7 1.7 no signal
679 Rash Macular 51 1.7 1.7 no signal
680 Eye Disorder 48 1.7 1.7 no signal
681 Generalised Oedema 18 1.7 1.7 no signal
682 Gastrointestinal Disorder 129 1.7 1.7 no signal
683 Renal Disorder 68 1.7 1.7 no signal
684 Nodule 19 1.7 1.7 no signal
685 Drug Toxicity 20 1.7 1.7 no signal
686 Rectal Haemorrhage 62 1.7 1.7 no signal
687 Vitreous Floaters 14 1.7 1.7 no signal
688 Pulmonary Hypertension 30 1.7 1.7 no signal
689 Product Dose Omission 95 1.7 1.7 no signal
690 Device Related Infection 22 1.7 1.7 no signal
691 Immunodeficiency 21 1.7 1.7 no signal
692 Lymphopenia 20 1.7 1.7 no signal
693 Product Use Complaint 22 1.7 1.7 no signal
694 Hypophagia 36 1.7 1.7 no signal
695 Femur Fracture 44 1.7 1.7 no signal
696 Haematemesis 36 1.7 1.7 no signal
697 Skin Discolouration 65 1.7 1.7 no signal
698 Urinary Retention 47 1.6 1.7 no signal
699 Fear 38 1.6 1.6 no signal
700 Salivary Hypersecretion 14 1.6 1.6 no signal
701 Impaired Work Ability 30 1.6 1.6 no signal
702 Red Blood Cell Count Decreased 40 1.6 1.6 no signal
703 Injection Site Bruising 110 1.6 1.6 no signal
704 Encephalopathy 34 1.6 1.6 no signal
705 Grand Mal Convulsion 13 1.6 1.6 no signal
706 Ventricular Tachycardia 23 1.6 1.6 no signal
707 Dystonia 27 1.6 1.6 no signal
708 Leukocytosis 25 1.6 1.6 no signal
709 Application Site Rash 19 1.6 1.6 no signal
710 Diarrhoea 881 1.6 1.6 no signal
711 Blood Alkaline Phosphatase Increased 34 1.6 1.6 no signal
712 Injection Site Haematoma 20 1.6 1.6 no signal
713 Head Discomfort 24 1.6 1.6 no signal
714 Pallor 37 1.6 1.6 no signal
715 Menorrhagia 27 1.6 1.6 no signal
716 Underdose 99 1.6 1.6 no signal
717 Prescribed Underdose 27 1.6 1.6 no signal
718 Cardiomyopathy 20 1.6 1.6 no signal
719 Dermatitis 28 1.6 1.6 no signal
720 Ejection Fraction Decreased 21 1.6 1.6 no signal
721 Pancreatitis 71 1.6 1.6 no signal
722 Tachycardia 119 1.6 1.6 no signal
723 Emotional Distress 162 1.6 1.6 no signal
724 Decreased Immune Responsiveness 13 1.6 1.6 no signal
725 Chromaturia 30 1.6 1.6 no signal
726 Haemoptysis 37 1.5 1.5 no signal
727 Hypersensitivity 245 1.5 1.6 no signal
728 Acute Myocardial Infarction 39 1.5 1.5 no signal
729 Abscess 21 1.5 1.5 no signal
730 Alopecia 259 1.5 1.5 no signal
731 Gingival Bleeding 18 1.5 1.5 no signal
732 Eructation 25 1.5 1.5 no signal
733 Visual Acuity Reduced 44 1.5 1.5 no signal
734 Hyperthyroidism 19 1.5 1.5 no signal
735 Nervous System Disorder 41 1.5 1.5 no signal
736 Body Temperature Decreased 13 1.5 1.5 no signal
737 Neoplasm 15 1.5 1.5 no signal
738 Inappropriate Schedule Of Product Administration 230 1.5 1.5 no signal
739 Ileus 16 1.5 1.5 no signal
740 Blood Thyroid Stimulating Hormone Increased 12 1.5 1.5 no signal
741 Drug Interaction 206 1.5 1.5 no signal
742 Taste Disorder 26 1.5 1.5 no signal
743 Blood Potassium Increased 21 1.5 1.5 no signal
744 Pyrexia 448 1.5 1.5 no signal
745 Delusion 20 1.5 1.5 no signal
746 Appendicitis 12 1.5 1.5 no signal
747 Cardiac Disorder 121 1.5 1.5 no signal
748 Splenomegaly 15 1.5 1.5 no signal
749 Gout 23 1.5 1.5 no signal
750 Skin Ulcer 33 1.5 1.5 no signal
751 Malaise 559 1.5 1.5 no signal
752 Skin Fissures 24 1.5 1.5 no signal
753 Discomfort 77 1.5 1.5 no signal
754 Pelvic Pain 23 1.5 1.5 no signal
755 Emotional Disorder 39 1.5 1.5 no signal
756 Drug Intolerance 121 1.5 1.5 no signal
757 Impaired Quality Of Life 18 1.5 1.5 no signal
758 Decreased Appetite 289 1.5 1.5 no signal
759 Glaucoma 24 1.5 1.5 no signal
760 Interstitial Lung Disease 60 1.4 1.5 no signal
761 Dry Skin 163 1.4 1.5 no signal
762 Injection Site Reaction 85 1.4 1.4 no signal
763 Aggression 62 1.4 1.4 no signal
764 Choking 24 1.4 1.4 no signal
765 White Blood Cell Count Decreased 134 1.4 1.4 no signal
766 Oral Herpes 24 1.4 1.4 no signal
767 Inappropriate Schedule Of Drug Administration 89 1.4 1.4 no signal
768 Respiratory Distress 34 1.4 1.4 no signal
769 Inflammation 63 1.4 1.4 no signal
770 Intentional Drug Misuse 26 1.4 1.4 no signal
771 Platelet Count Increased 16 1.4 1.4 no signal
772 Generalised Tonic-clonic Seizure 20 1.4 1.4 no signal
773 Injection Site Mass 45 1.4 1.4 no signal
774 Intentional Product Misuse 106 1.4 1.4 no signal
775 Swelling Face 79 1.4 1.4 no signal
776 Therapeutic Response Decreased 73 1.4 1.4 no signal
777 Libido Decreased 15 1.4 1.4 no signal
778 Injection Site Pain 367 1.4 1.4 no signal
779 Gastric Haemorrhage 14 1.4 1.4 no signal
780 Intentional Overdose 77 1.4 1.4 no signal
781 Urticaria 201 1.4 1.4 no signal
782 Osteonecrosis 40 1.4 1.4 no signal
783 Stomatitis 73 1.4 1.4 no signal
784 Brain Neoplasm 11 1.4 1.4 no signal
785 Erythema 245 1.4 1.4 no signal
786 Injection Site Erythema 147 1.4 1.4 no signal
787 Bacteraemia 14 1.4 1.4 no signal
788 Cardio-respiratory Arrest 50 1.4 1.4 no signal
789 Product Quality Issue 160 1.4 1.4 no signal
790 Diabetes Mellitus Inadequate Control 21 1.4 1.4 no signal
791 Bone Loss 18 1.4 1.4 no signal
792 Rash 514 1.4 1.4 no signal
793 Product Adhesion Issue 42 1.4 1.4 no signal
794 Blood Glucose Decreased 57 1.4 1.4 no signal
795 Pulmonary Oedema 53 1.4 1.4 no signal
796 Application Site Erythema 31 1.4 1.4 no signal
797 Treatment Noncompliance 64 1.4 1.4 no signal
798 Myocardial Infarction 207 1.4 1.4 no signal
799 Diarrhoea Haemorrhagic 11 1.4 1.4 no signal
800 Injection Site Pruritus 78 1.4 1.4 no signal
801 Aspartate Aminotransferase Increased 62 1.4 1.4 no signal
802 Squamous Cell Carcinoma 11 1.4 1.4 no signal
803 Injection Site Discomfort 12 1.4 1.4 no signal
804 Injection Site Induration 15 1.4 1.4 no signal
805 Delirium 40 1.4 1.4 no signal
806 Glomerular Filtration Rate Decreased 14 1.3 1.3 no signal
807 Pulmonary Fibrosis 22 1.3 1.3 no signal
808 Tooth Loss 24 1.3 1.3 no signal
809 Rash Pruritic 62 1.3 1.3 no signal
810 Multiple Fractures 19 1.3 1.3 no signal
811 Application Site Pruritus 26 1.3 1.3 no signal
812 Conjunctivitis 21 1.3 1.3 no signal
813 Full Blood Count Abnormal 12 1.3 1.3 no signal
814 Internal Haemorrhage 13 1.3 1.3 no signal
815 Pneumothorax 18 1.3 1.3 no signal
816 Epistaxis 85 1.3 1.3 no signal
817 No Therapeutic Response 14 1.3 1.3 no signal
818 Electrolyte Imbalance 13 1.3 1.3 no signal
819 Pericardial Effusion 26 1.3 1.3 no signal
820 Injection Site Discolouration 14 1.3 1.3 no signal
821 Anaemia 215 1.3 1.3 no signal
822 Application Site Irritation 14 1.3 1.3 no signal
823 Malignant Melanoma 15 1.3 1.3 no signal
824 Gastrointestinal Haemorrhage 94 1.3 1.3 no signal
825 Cerebrovascular Accident 190 1.3 1.3 no signal
826 Therapy Interrupted 77 1.3 1.3 no signal
827 Product Availability Issue 25 1.3 1.3 no signal
828 Paraesthesia Oral 16 1.3 1.3 no signal
829 Rash Papular 25 1.3 1.3 no signal
830 Drug Effect Incomplete 41 1.3 1.3 no signal
831 Rash Erythematous 52 1.3 1.3 no signal
832 Faeces Discoloured 24 1.3 1.3 no signal
833 Alanine Aminotransferase Increased 68 1.3 1.3 no signal
834 Oesophagitis 12 1.3 1.3 no signal
835 Adverse Drug Reaction 98 1.3 1.3 no signal
836 Vaginal Discharge 11 1.3 1.3 no signal
837 Full Blood Count Decreased 22 1.3 1.3 no signal
838 Myoclonus 13 1.3 1.3 no signal
839 Adrenal Insufficiency 13 1.3 1.3 no signal
840 Diabetic Ketoacidosis 26 1.3 1.3 no signal
841 Respiratory Failure 79 1.3 1.3 no signal
842 Cyanosis 17 1.3 1.3 no signal
843 Glossodynia 24 1.3 1.3 no signal
844 Deformity 10 1.2 1.2 no signal
845 Lung Disorder 52 1.2 1.2 no signal
846 Petechiae 11 1.2 1.2 no signal
847 Injection Site Swelling 80 1.2 1.2 no signal
848 Tardive Dyskinesia 30 1.2 1.2 no signal
849 Product Administration Error 21 1.2 1.2 no signal
850 Hyperglycaemia 38 1.2 1.2 no signal
851 Transfusion 11 1.2 1.2 no signal
852 Atrial Fibrillation 102 1.2 1.2 no signal
853 Drug Dose Omission 175 1.2 1.2 no signal
854 Injection Site Extravasation 13 1.2 1.2 no signal
855 Product Taste Abnormal 14 1.2 1.2 no signal
856 Drug Dependence 169 1.2 1.2 no signal
857 Therapy Change 10 1.2 1.2 no signal
858 Restlessness 38 1.2 1.2 no signal
859 Product Use In Unapproved Indication 253 1.2 1.2 no signal
860 Hair Colour Changes 13 1.2 1.2 no signal
861 Liver Function Test Increased 22 1.2 1.2 no signal
862 Dysgeusia 77 1.2 1.2 no signal
863 Pancreatitis Acute 23 1.2 1.2 no signal
864 Deafness 27 1.2 1.2 no signal
865 Infusion Related Reaction 68 1.2 1.2 no signal
866 Sexual Dysfunction 12 1.2 1.2 no signal
867 Eyelid Oedema 12 1.2 1.2 no signal
868 Basal Cell Carcinoma 16 1.2 1.2 no signal
869 Blood Pressure Systolic Increased 20 1.2 1.2 no signal
870 Psychomotor Hyperactivity 17 1.2 1.2 no signal
871 Laboratory Test Abnormal 30 1.2 1.2 no signal
872 Hepatic Cirrhosis 19 1.2 1.2 no signal
873 Product Use Issue 190 1.2 1.2 no signal
874 Hepatitis 26 1.2 1.2 no signal
875 Accidental Overdose 37 1.2 1.2 no signal
876 Product Physical Issue 20 1.2 1.2 no signal
877 Injection Site Nodule 11 1.2 1.2 no signal
878 Eye Pruritus 33 1.2 1.2 no signal
879 Blood Glucose Fluctuation 11 1.2 1.2 no signal
880 Mouth Ulceration 21 1.2 1.2 no signal
881 Hypoaesthesia Oral 15 1.2 1.2 no signal
882 Contraindicated Product Administered 30 1.2 1.2 no signal
883 Liver Disorder 44 1.2 1.2 no signal
884 Swollen Tongue 31 1.2 1.2 no signal
885 Hypothermia 10 1.2 1.2 no signal
886 Obstructive Airways Disorder 11 1.2 1.2 no signal
887 Rhabdomyolysis 41 1.1 1.1 no signal
888 Dermatitis Atopic 49 1.1 1.1 no signal
889 Adverse Reaction 13 1.1 1.1 no signal
890 Bone Density Decreased 31 1.1 1.1 no signal
891 Bronchospasm 14 1.1 1.1 no signal
892 Hypercalcaemia 12 1.1 1.1 no signal
893 Blood Glucose Abnormal 18 1.1 1.1 no signal
894 Drug Ineffective For Unapproved Indication 54 1.1 1.1 no signal
895 Pleural Effusion 59 1.1 1.1 no signal
896 Lymphoma 15 1.1 1.1 no signal
897 Shock 22 1.1 1.1 no signal
898 Hepatic Encephalopathy 9 1.1 1.1 no signal
899 Hair Texture Abnormal 13 1.1 1.1 no signal
900 Skin Exfoliation 80 1.1 1.1 no signal
901 Haematochezia 53 1.1 1.1 no signal
902 Acute Respiratory Distress Syndrome 17 1.1 1.1 no signal
903 Colitis 36 1.1 1.1 no signal
904 Drug Ineffective 1,247 1.1 1.1 no signal
905 Incorrect Drug Administration Duration 27 1.1 1.1 no signal
906 Therapeutic Product Effect Decreased 42 1.1 1.1 no signal
907 Needle Issue 27 1.1 1.1 no signal
908 Injection Site Haemorrhage 74 1.1 1.1 no signal
909 Hospitalisation 142 1.1 1.1 no signal
910 Altered State Of Consciousness 20 1.1 1.1 no signal
911 Neuroleptic Malignant Syndrome 11 1.1 1.1 no signal
912 Injection Site Warmth 19 1.1 1.1 no signal
913 Ankylosing Spondylitis 12 1.1 1.1 no signal
914 Ocular Hyperaemia 43 1.1 1.1 no signal
915 Therapy Non-responder 41 1.1 1.1 no signal
916 Product Preparation Error 19 1.1 1.1 no signal
917 Haemoglobin Decreased 94 1.1 1.1 no signal
918 Adverse Event 84 1.1 1.1 no signal
919 Haematuria 31 1.1 1.1 no signal
920 Drug Dispensing Error 14 1.1 1.1 no signal
921 Red Blood Cell Sedimentation Rate Increased 10 1.1 1.1 no signal
922 Eye Haemorrhage 12 1.0 1.0 no signal
923 Eye Irritation 50 1.0 1.0 no signal
924 Hypertensive Crisis 10 1.0 1.0 no signal
925 Toxicity To Various Agents 150 1.0 1.0 no signal
926 Hypoglycaemia 43 1.0 1.0 no signal
927 Rebound Effect 10 1.0 1.0 no signal
928 Drug Level Decreased 9 1.0 1.0 no signal
929 Eczema 44 1.0 1.0 no signal
930 Blood Creatinine Increased 57 1.0 1.0 no signal
931 Overdose 188 1.0 1.0 no signal
932 Arrhythmia 41 1.0 1.0 no signal
933 Blindness 35 1.0 1.0 no signal
934 Erythema Multiforme 8 1.0 1.0 no signal
935 Post Procedural Haemorrhage 10 1.0 1.0 no signal
936 Madarosis 10 1.0 1.0 no signal
937 Hyponatraemia 48 1.0 1.0 no signal
938 Epilepsy 26 1.0 1.0 no signal
939 Hypocalcaemia 16 1.0 1.0 no signal
940 Blood Count Abnormal 13 1.0 1.0 no signal
941 Breast Pain 9 1.0 1.0 no signal
942 Cardiogenic Shock 12 1.0 1.0 no signal
943 Polyneuropathy 10 1.0 1.0 no signal
944 Blood Glucose Increased 159 1.0 1.0 no signal
945 Macular Degeneration 10 1.0 1.0 no signal
946 Abdominal Pain Lower 21 1.0 1.0 no signal
947 Anosmia 12 1.0 1.0 no signal
948 Neoplasm Malignant 55 1.0 1.0 no signal
949 Drug Prescribing Error 16 1.0 1.0 no signal
950 Coeliac Disease 8 1.0 1.0 no signal
951 Pain Of Skin 22 1.0 1.0 no signal
952 Lip Swelling 27 0.9 0.9 no signal
953 Septic Shock 35 0.9 0.9 no signal
954 Stevens-johnson Syndrome 18 0.9 0.9 no signal
955 Therapeutic Product Effect Incomplete 57 0.9 0.9 no signal
956 Osteonecrosis Of Jaw 20 0.9 0.9 no signal
957 Dermatitis Allergic 10 0.9 0.9 no signal
958 Ageusia 20 0.9 0.9 no signal
959 Haemorrhage Intracranial 12 0.9 0.9 no signal
960 Lung Neoplasm Malignant 33 0.9 0.9 no signal
961 Drug Eruption 14 0.9 0.9 no signal
962 Intentional Self-injury 16 0.9 0.9 no signal
963 Medication Error 44 0.9 0.9 no signal
964 Fracture 15 0.9 0.9 no signal
965 Dementia 22 0.9 0.9 no signal
966 Blood Creatine Phosphokinase Increased 23 0.9 0.9 no signal
967 Helicobacter Infection 8 0.9 0.9 no signal
968 Myocardial Ischaemia 9 0.9 0.9 no signal
969 Product Dispensing Error 17 0.9 0.9 no signal
970 Frequent Bowel Movements 21 0.9 0.9 no signal
971 Amenorrhoea 13 0.9 0.9 no signal
972 Electrocardiogram Qt Prolonged 28 0.9 0.9 no signal
973 Haemorrhage 81 0.9 0.9 no signal
974 General Physical Health Deterioration 89 0.9 0.9 no signal
975 Folliculitis 8 0.9 0.9 no signal
976 Vasculitis 9 0.9 0.9 no signal
977 Face Oedema 13 0.9 0.9 no signal
978 Rash Generalised 20 0.9 0.9 no signal
979 Cardiac Arrest 63 0.9 0.9 no signal
980 Pulmonary Arterial Hypertension 11 0.9 0.9 no signal
981 Exposure Via Skin Contact 17 0.9 0.9 no signal
982 Product Substitution Issue 43 0.9 0.9 no signal
983 Meningioma 11 0.9 0.9 no signal
984 Hypoacusis 32 0.9 0.9 no signal
985 Thyroid Cancer 9 0.9 0.9 no signal
986 Tachypnoea 10 0.9 0.9 no signal
987 Photosensitivity Reaction 12 0.9 0.9 no signal
988 Extra Dose Administered 29 0.8 0.8 no signal
989 Ventricular Fibrillation 8 0.8 0.8 no signal
990 Parkinsonism 7 0.8 0.8 no signal
991 Intestinal Perforation 8 0.8 0.8 no signal
992 Upper Gastrointestinal Haemorrhage 12 0.8 0.8 no signal
993 Hospice Care 7 0.8 0.8 no signal
994 Ill-defined Disorder 43 0.8 0.8 no signal
995 Dialysis 10 0.8 0.8 no signal
996 Liver Injury 17 0.8 0.8 no signal
997 Mydriasis 9 0.8 0.8 no signal
998 Blood Bilirubin Increased 19 0.8 0.8 no signal
999 Device Issue 61 0.8 0.8 no signal
1000 Erectile Dysfunction 18 0.8 0.8 no signal
1001 Subdural Haematoma 10 0.8 0.8 no signal
1002 Off Label Use 604 0.8 0.8 no signal
1003 Platelet Count Decreased 74 0.8 0.8 no signal
1004 Drug Abuse 58 0.8 0.8 no signal
1005 Pregnancy 14 0.8 0.8 no signal
1006 Proteinuria 13 0.8 0.8 no signal
1007 Wrong Technique In Product Usage Process 139 0.8 0.8 no signal
1008 Incorrect Dose Administered 154 0.8 0.8 no signal
1009 Application Site Pain 15 0.8 0.8 no signal
1010 Vaginal Haemorrhage 29 0.8 0.8 no signal
1011 Neutrophil Count Increased 7 0.8 0.8 no signal
1012 Glycosylated Haemoglobin Increased 17 0.8 0.8 no signal
1013 Skeletal Injury 7 0.8 0.8 no signal
1014 Drug Level Increased 11 0.8 0.8 no signal
1015 Metabolic Acidosis 21 0.8 0.8 no signal
1016 Device Leakage 28 0.8 0.8 no signal
1017 Skin Cancer 14 0.8 0.8 no signal
1018 Renal Impairment 54 0.8 0.8 no signal
1019 Drug Administration Error 20 0.7 0.7 no signal
1020 Blood Test Abnormal 9 0.7 0.7 no signal
1021 Extrapyramidal Disorder 16 0.7 0.7 no signal
1022 Expired Product Administered 21 0.7 0.7 no signal
1023 Hepatic Failure 19 0.7 0.7 no signal
1024 Anaphylactic Shock 16 0.7 0.7 no signal
1025 Intraocular Pressure Increased 8 0.7 0.7 no signal
1026 Psoriasis 81 0.7 0.7 no signal
1027 Skin Burning Sensation 43 0.7 0.7 no signal
1028 Colon Cancer 9 0.7 0.7 no signal
1029 Hyperkalaemia 21 0.7 0.7 no signal
1030 Sars-cov-2 Test Positive 8 0.7 0.7 no signal
1031 Injury Associated With Device 12 0.7 0.7 no signal
1032 Device Malfunction 40 0.7 0.7 no signal
1033 Breast Cancer Female 16 0.7 0.7 no signal
1034 Plasma Cell Myeloma 23 0.7 0.7 no signal
1035 Cardiovascular Disorder 15 0.7 0.7 no signal
1036 Breast Cancer 55 0.7 0.7 no signal
1037 Leukopenia 29 0.7 0.7 no signal
1038 Prostatic Specific Antigen Increased 8 0.7 0.7 no signal
1039 Neurotoxicity 10 0.7 0.7 no signal
1040 Lung Infection 9 0.7 0.7 no signal
1041 Sickle Cell Anaemia With Crisis 9 0.7 0.7 no signal
1042 Skin Reaction 8 0.7 0.7 no signal
1043 Sudden Death 6 0.7 0.7 no signal
1044 Cerebral Haemorrhage 20 0.7 0.7 no signal
1045 Device Defective 9 0.6 0.6 no signal
1046 Brain Oedema 7 0.6 0.6 no signal
1047 Product Prescribing Issue 11 0.6 0.6 no signal
1048 Hepatic Function Abnormal 20 0.6 0.6 no signal
1049 Mucosal Inflammation 14 0.6 0.6 no signal
1050 Dysmenorrhoea 7 0.6 0.6 no signal
1051 Device Dislocation 23 0.6 0.6 no signal
1052 Circulatory Collapse 9 0.6 0.6 no signal
1053 Posterior Reversible Encephalopathy Syndrome 5 0.6 0.6 no signal
1054 Acne 40 0.6 0.6 no signal
1055 International Normalised Ratio Increased 15 0.6 0.6 no signal
1056 Uveitis 7 0.6 0.6 no signal
1057 Eosinophilia 9 0.6 0.6 no signal
1058 Acute Hepatic Failure 7 0.6 0.6 no signal
1059 Akathisia 7 0.6 0.6 no signal
1060 Caesarean Section 6 0.6 0.6 no signal
1061 Inflammatory Bowel Disease 5 0.6 0.6 no signal
1062 Device Occlusion 7 0.6 0.6 no signal
1063 Blindness Unilateral 7 0.6 0.6 no signal
1064 Incorrect Product Administration Duration 10 0.6 0.6 no signal
1065 Hepatitis C 6 0.6 0.6 no signal
1066 Poor Quality Product Administered 5 0.6 0.6 no signal
1067 Device Breakage 19 0.6 0.6 no signal
1068 Menstruation Delayed 5 0.6 0.6 no signal
1069 Metastases To Central Nervous System 6 0.5 0.5 no signal
1070 Therapy Partial Responder 7 0.5 0.5 no signal
1071 Metrorrhagia 8 0.5 0.5 no signal
1072 Disease Progression 54 0.5 0.5 no signal
1073 Skin Irritation 21 0.5 0.5 no signal
1074 Syringe Issue 8 0.5 0.5 no signal
1075 Rash Maculo-papular 10 0.5 0.5 no signal
1076 Accidental Exposure To Product 45 0.5 0.5 no signal
1077 Incorrect Product Storage 6 0.5 0.5 no signal
1078 Cerebral Infarction 11 0.5 0.5 no signal
1079 Colitis Ulcerative 20 0.5 0.5 no signal
1080 No Adverse Event 79 0.5 0.5 no signal
1081 Product Administered At Inappropriate Site 8 0.5 0.5 no signal
1082 Disease Recurrence 21 0.5 0.5 no signal
1083 Blood Lactate Dehydrogenase Increased 7 0.5 0.5 no signal
1084 Metastases To Lung 5 0.5 0.5 no signal
1085 Ovarian Cancer 4 0.5 0.5 no signal
1086 Leukaemia 4 0.5 0.5 no signal
1087 Eye Inflammation 4 0.5 0.5 no signal
1088 Cardiac Failure 34 0.5 0.5 no signal
1089 Product Prescribing Error 10 0.5 0.5 no signal
1090 Pericarditis 7 0.5 0.5 no signal
1091 Device Deployment Issue 5 0.5 0.5 no signal
1092 Menstruation Irregular 11 0.5 0.5 no signal
1093 Schizophrenia 5 0.5 0.5 no signal
1094 Melaena 9 0.5 0.5 no signal
1095 Pneumonitis 11 0.5 0.5 no signal
1096 Device Use Issue 7 0.5 0.5 no signal
1097 Treatment Failure 32 0.5 0.5 no signal
1098 Complication Of Device Insertion 7 0.4 0.4 no signal
1099 Nephropathy Toxic 4 0.4 0.4 no signal
1100 C-reactive Protein Increased 13 0.4 0.4 no signal
1101 Fistula 4 0.4 0.4 no signal
1102 Incorrect Dose Administered By Device 9 0.4 0.4 no signal
1103 Status Epilepticus 4 0.4 0.4 no signal
1104 Lower Respiratory Tract Infection 16 0.4 0.4 no signal
1105 Thrombocytopenia 39 0.4 0.4 no signal
1106 Abortion Spontaneous 14 0.4 0.4 no signal
1107 Neutrophil Count Decreased 14 0.4 0.4 no signal
1108 Neoplasm Progression 12 0.4 0.4 no signal
1109 Ischaemic Stroke 6 0.4 0.4 no signal
1110 Maternal Exposure During Pregnancy 29 0.4 0.4 no signal
1111 Dependence 18 0.4 0.4 no signal
1112 Product Packaging Issue 3 0.4 0.4 no signal
1113 Death 276 0.4 0.4 no signal
1114 Device Difficult To Use 21 0.4 0.4 no signal
1115 Angioedema 14 0.4 0.4 no signal
1116 Poisoning 4 0.4 0.4 no signal
1117 Metastases To Bone 5 0.4 0.4 no signal
1118 Pancytopenia 17 0.4 0.4 no signal
1119 Embedded Device 3 0.4 0.4 no signal
1120 Cytomegalovirus Infection 5 0.4 0.4 no signal
1121 Circumstance Or Information Capable Of Leading To Medication Error 10 0.3 0.3 no signal
1122 Neutropenia 38 0.3 0.3 no signal
1123 Pancreatic Carcinoma 8 0.3 0.3 no signal
1124 Product Packaging Quantity Issue 3 0.3 0.3 no signal
1125 Drug Exposure During Pregnancy 9 0.3 0.3 no signal
1126 Incorrect Route Of Drug Administration 9 0.3 0.3 no signal
1127 Exposure During Pregnancy 15 0.3 0.3 no signal
1128 Product Complaint 6 0.3 0.3 no signal
1129 Abnormal Weight Gain 3 0.3 0.3 no signal
1130 Tuberculosis 3 0.3 0.3 no signal
1131 Hand Deformity 3 0.3 0.3 no signal
1132 Sopor 3 0.3 0.3 no signal
1133 Wrong Technique In Device Usage Process 10 0.3 0.3 no signal
1134 Palmar-plantar Erythrodysaesthesia Syndrome 5 0.2 0.2 no signal
1135 Product Storage Error 18 0.2 0.2 no signal
1136 Malignant Neoplasm Progression 21 0.2 0.2 no signal
1137 Device Use Error 7 0.2 0.2 no signal
1138 Drug Withdrawal Syndrome Neonatal 3 0.2 0.2 no signal
1139 Device Adhesion Issue 3 0.2 0.2 no signal
1140 Prostate Cancer 16 0.2 0.2 no signal
1141 Renal Cancer 8 0.2 0.2 no signal
1142 Gastric Cancer 4 0.2 0.2 no signal
1143 Gynaecomastia 4 0.1 0.1 no signal
1144 Drug Dose Omission By Device 9 0.1 0.1 no signal
1145 Bladder Cancer 7 0.1 0.1 no signal
1146 Oesophageal Carcinoma 3 0.1 0.1 no signal
1147 Device Expulsion 5 0.1 0.1 no signal
1148 Colorectal Cancer 3 0.1 0.1 no signal