Reaction

Cartilage Injury reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,443 reports · 36 co-occurring drugs

As of the last recalculation, Cartilage Injury appears in 2,443 FAERS reports alongside 36 co-occurring drug terms. The strongest observed disproportionality signal is DOXEPIN HYDROCHLORIDE (PRR 12.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Doxepin Hydrochloride	19	12.9	12.9
Doxepin	15	12.7	12.7
Asfotase Alfa	13	11.1	11.1
Tizanidine Hydrochloride	22	10.5	10.5
Adalimumab	611	9.5	9.5
Leflunomide	95	8.0	8.0
Ciprofolxacin	63	7.7	7.7
Ciprofloxacin Tablets	63	7.7	7.7
Upadacitinib	71	7.6	7.6
Ciprofloxacin	77	7.3	7.4
Meloxicam	49	7.3	7.3
Ciprofloxacin Hydrochloride	79	7.1	7.1
Sodium Oxybate	53	7.0	7.0
Calcium, Magnesium, Potassium, And Sodium Oxybates	7	6.9	6.9
Celecoxib	97	6.5	6.5
Icosapent Ethyl	6	6.0	6.0
Liothyronine Sodium	6	5.9	5.9
Modafinil	21	5.6	5.6
Ibuprofen Tablets, Coated	25	5.1	5.1
Tizanidine	14	5.0	5.0
Ibuprofen Sodium	25	5.0	5.0
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	20	4.9	4.9
Interferon Beta-1A	93	4.2	4.2
Risankizumab-Rzaa	39	4.1	4.1
Tofacitinib Citrate	6	3.9	3.9
Loratadine And Pseudoephedrine Sulfate	3	3.2	3.2
Ocrelizumab	23	3.2	3.2
Tofacitinib	64	3.0	3.0
Benralizumab	7	3.0	3.0
Cariprazine	3	2.7	2.7
Ranitidine Hydrochloride	17	2.7	2.7
Medroxyprogesterone Acetate	13	2.2	2.2
Fremanezumab-Vfrm	3	2.2	2.2
Natalizumab	46	2.2	2.2
Rimegepant Sulfate	3	2.0	2.0
Relugolix	4	1.4	1.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.