Reaction

Spinal Fusion Surgery reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,965 reports · 199 co-occurring drugs

As of the last recalculation, Spinal Fusion Surgery appears in 3,965 FAERS reports alongside 199 co-occurring drug terms. The strongest observed disproportionality signal is DICLOFENAC POTASSIUM, FILM COATED (PRR 75.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diclofenac Potassium, Film Coated	118	75.8	76.9
Diclofenac Potassium Tablets	118	75.8	76.9
Diclofenac Potassium	121	60.6	61.3
Cortisone Acetate	131	57.6	58.2
Pseudoephedrine Hydrochloride	102	53.5	54.0
Pseudoephedrine Hcl	102	49.9	50.3
Desoximetasone	151	43.2	43.5
Tofacitinib Citrate	94	38.5	38.8
Naproxen Sodium Tablet, Coated	96	38.1	38.4
Naproxen Sodium, Coated Tablets	96	38.1	38.4
Naproxen Sodium 220Mg	96	38.1	38.3
Hydrocortisone Sodium Succinate	65	36.9	37.1
Diltiazem Hydrochloride Extended-Release Tablets	54	25.2	25.4
Doxyclycline Hyclate	75	23.5	23.6
Diclofenac Sodium 1%	143	21.8	21.8
Diclofenac Sodium Topical	143	21.8	21.8
Diclofenac Sodium Topical Gel, 1%	143	21.7	21.8
Cetirizine Hydrochloride Allergy	121	21.6	21.7
Cetirizine Hydrochloride Tablets	121	21.6	21.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	31	19.0	19.1
Diphenhydramine Hydrochloride Capsule, Liquid Filled	76	19.0	19.1
Alendronate Sodium	312	17.5	17.6
Chlorhexidine Gluconate	30	17.4	17.4
Calcium Gluconate	39	17.1	17.2
Sarilumab	82	16.6	16.7
Triamcinolone Acetonide Ointment Usp, 0.05%	68	15.5	15.5
Upadacitinib	224	15.2	15.3
Sulfasalazine	187	13.1	13.1
Quetiapine Fumarate	71	12.8	12.9
Adalimumab-Fkjp	110	12.8	12.8
Adalimumab-Aaty	109	12.4	12.4
Acetaminophen And Codeine	28	12.1	12.2
Adalimumab-Adaz	117	12.0	12.0
Diclofenac	187	11.9	11.9
Triamcinolone Acetonide	68	11.7	11.8
Erythromycin	41	11.6	11.6
Antacid	102	11.5	11.6
Oxycodone And Acetaminophen Tablets	26	11.5	11.5
Tramadol Hydrochloride	81	11.5	11.5
Methocarbamol	49	11.5	11.5
Sodium Oxybate	137	11.3	11.3
Golimumab	176	11.2	11.2
Isopropyl Alcohol	70	11.0	11.1
Hydroxychloroquine Sulfate	182	10.9	11.0
Cetirizine	155	10.9	10.9
Methylprednisolone Sodium Succinate	93	10.7	10.8
Methocarbamol Tablets	34	10.7	10.8
Tizanidine Hydrochloride	36	10.5	10.6
Minocycline	23	10.4	10.4
Diltiazem Hydrochloride	65	10.0	10.0
Hydroxychloroquine	137	9.9	10.0
Leflunomide	189	9.9	9.9
Armodafinil	39	9.8	9.8
Alcohol	69	9.5	9.5
Calcium Carbonate	114	9.1	9.2
Certolizumab Pegol	193	9.0	9.0
Risankizumab-Rzaa	129	8.5	8.5
Risedronate Sodium	49	8.4	8.4
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	47	8.2	8.2
Abatacept	207	8.2	8.2
Ascorbic Acid	35	8.0	8.0
Tocilizumab	166	7.9	7.9
Azathioprine	129	7.9	7.9
Doxycycline	99	7.8	7.8
Carisoprodol	28	7.8	7.8
Doxycycline Hyclate	97	7.7	7.7
Hydrocortisone Acetate	103	7.6	7.6
Cetiirizine	60	7.5	7.5
Ustekinumab	139	7.4	7.4
Celecoxib	176	7.3	7.3
Diclofenac Sodium	197	7.2	7.2
Hydrocortisone	118	7.1	7.1
Mesalamine	74	7.0	7.0
Tofacitinib	230	6.9	6.9
Cetirizine Hydrochloride	198	6.6	6.6
Meloxicam	71	6.5	6.5
Losartan Potassium And Hydrochlorothiazide	14	6.3	6.4
Oxycodone And Acetaminophen	28	6.3	6.4
Morphine	88	6.3	6.3
Naproxen Sodium	158	6.0	6.0
Alendronate Sodium Tablet	21	6.0	6.0
Modafinil	36	5.9	5.9
Tretinoin	9	5.8	5.8
Etanercept	577	5.8	5.8
Tizanidine	26	5.8	5.8
Icosapent Ethyl	9	5.6	5.6
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	37	5.5	5.5
Vitamin C	94	5.5	5.5
Romosozumab-Aqqg	14	5.4	5.4
Folic Acid	244	5.4	5.4
Fosaprepitant Dimeglumine	14	5.4	5.4
Anti-Itch	67	5.3	5.3
Anti-Pruritic	67	5.3	5.3
Antipruritic (Anti-Itch)	67	5.3	5.3
Cool Relief Gel With Aloe	67	5.3	5.3
Drs. Hydrocortisone	67	5.3	5.3
Hydrocortisone Continuous Spray	67	5.3	5.3
Hydrocortisone Spray	67	5.3	5.3
Anti-Itch Cream	67	5.3	5.3
Hydrocortisone Lotion	67	5.3	5.3
Hydrocortisone Cream 1%	67	5.3	5.3
Hydrocortisone Cream 1/2%	67	5.3	5.3
Hydrocortisone 1%	67	5.3	5.3
Testosterone Cypionate	9	5.3	5.3
Naproxen	78	5.3	5.3
Hydrocortisone Cream	67	5.3	5.3
Cyclobenzaprine Hydrochloride	9	5.3	5.3
Dicyclomine Hydrochloride	14	5.2	5.2
Indomethacin	13	5.2	5.2
Hyoscyamine Sulfate	9	5.2	5.2
Cyanocobalamin	32	5.1	5.1
Cyclobenzaprine	47	5.0	5.0
Oxycodone Hydrochloride And Acetaminophen	92	5.0	5.0
Adalimumab	589	5.0	5.0
Oxycodone	169	4.9	4.9
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	38	4.8	4.8
Liothyronine Sodium	8	4.8	4.8
Apremilast	131	4.8	4.8
Teriparatide	101	4.8	4.8
Oxycodone Hydrochloride	191	4.8	4.8
Botulinum Toxin Type A	11	4.7	4.7
Eptinezumab-Jjmr	8	4.6	4.6
Infliximab	185	4.6	4.6
Baclofen	74	4.6	4.6
Morphine Sulfate	103	4.5	4.6
Calcium	125	4.5	4.5
Methotrexate	337	4.5	4.5
Abaloparatide	25	4.5	4.5
Carboxymethylcellulose Sodium	8	4.5	4.5
Interferon Beta-1A	158	4.4	4.4
Secukinumab	132	4.4	4.4
Estradiol Gel 0.1%	37	4.3	4.3
Estradiol Transdermal	37	4.3	4.3
Aprepitant	15	4.3	4.3
Pregabalin	212	4.3	4.3
Fish Oil	72	4.2	4.2
Vedolizumab	67	4.1	4.1
Ropinirole	12	4.1	4.1
Brivaracetam	7	4.1	4.1
Duloxetine Hydrochloride	142	4.1	4.1
Oxymorphone Hydrochloride	9	4.1	4.1
Hydrocodone Bitartrate And Acetaminophen	43	4.0	4.0
Methotrexate Sodium	343	4.0	4.0
Ketoconazole Foam	11	3.9	3.9
Ketoconazole Cream, 2%	11	3.9	3.9
Lubiprostone	7	3.9	3.9
Gabapentin	251	3.8	3.8
Hydromorphone Hydrochloride	64	3.7	3.7
Chlorthalidone	8	3.6	3.6
Raloxifene Hydrochloride	10	3.6	3.6
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	6	3.5	3.5
Teriflunomide	30	3.5	3.5
Salicylic Acid	35	3.5	3.5
Methylphenidate Hydrochloride	39	3.5	3.5
Conjugated Estrogens	38	3.4	3.4
Estrogens, Conjugated	38	3.4	3.4
Anakinra	10	3.2	3.2
Estradiol	51	3.1	3.1
Agalsidase Beta	5	2.8	2.8
Methadone	22	2.7	2.7
Fexofenadine Hydrochloride	11	2.7	2.7
Fluticasone Propionate And Salmeterol	21	2.7	2.7
Denosumab	96	2.5	2.5
Mirabegron	18	2.4	2.4
Emtricitabine And Tenofovir Disoproxil Fumarate	21	2.4	2.4
Tenofovir Disoproxil Fumarate	15	2.4	2.4
Carbidopa And Levodopa	21	2.3	2.3
Emtricitabine And Tenofovir Alafenamide	5	2.3	2.3
Oral Semaglutide	32	2.3	2.3
Acetaminophen, Aspirin, And Caffeine	9	2.2	2.2
Linaclotide	11	2.2	2.2
Vortioxetine	7	2.2	2.2
Belimumab	13	2.2	2.2
Esketamine Hydrochloride	7	2.1	2.1
Cannabidiol	9	2.0	2.0
Onabotulinumtoxina	29	2.0	2.0
Buprenorphine Hydrochloride, Naloxone Hydrochloride	9	2.0	2.0
Natalizumab	66	1.9	1.9
Umeclidinium Bromide And Vilanterol Trifenatate	6	1.9	1.9
Tapentadol Hydrochloride	12	1.9	1.9
Fremanezumab-Vfrm	4	1.8	1.8
Erenumab-Aooe	19	1.8	1.8
Guselkumab	12	1.8	1.8
Glatiramer Acetate	20	1.8	1.8
Buprenorphine	29	1.6	1.7
Exenatide	16	1.6	1.6
Dimethyl Fumarate	37	1.6	1.6
Brexpiprazole	5	1.6	1.6
Conjugated Estrogens And Medroxyprogesterone Acetate	7	1.6	1.6
Bimekizumab	6	1.5	1.5
Hydrocodone Bitartrate	12	1.5	1.5
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	5	1.4	1.4
Droxidopa	5	1.2	1.2
Varenicline Tartrate	18	1.2	1.2
Patiromer	3	1.1	1.1
Relugolix	5	1.1	1.1
Valbenazine	5	1.0	1.0
Dupilumab	88	1.0	1.0
Evolocumab	28	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.