Reaction

Exposure To Toxic Agent reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,180 reports · 49 co-occurring drugs

As of the last recalculation, Exposure To Toxic Agent appears in 3,180 FAERS reports alongside 49 co-occurring drug terms. The strongest observed disproportionality signal is ACETAMINOPHEN TABLET EXTENDED RELEASE (PRR 92.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Acetaminophen Tablet Extended Release	1,696	92.1	92.7
Pain Reliever	1,696	92.1	92.7
Acetaminophen 500Mg	1,696	92.0	92.6
Ethyl Alcohol	336	90.4	91.5
Isopropyl Alcohol	337	72.9	73.6
Alcohol	336	63.2	63.8
Acetaminophen	1,706	52.7	52.9
Naproxen Sodium Tablet, Coated	56	27.5	27.6
Naproxen Sodium, Coated Tablets	56	27.5	27.6
Naproxen Sodium 220Mg	56	27.5	27.6
Loperamide Hydrochloride Oral	36	23.3	23.4
Loperamide Hcl	36	18.5	18.6
Diphenhydramine Hcl	25	14.8	14.8
Pseudoephedrine Hydrochloride	22	14.1	14.1
Pseudoephedrine Hcl	23	13.8	13.8
Amphetamine	14	11.1	11.1
Fexofenadine Hydrochloride	30	9.1	9.1
Bupropion	55	8.2	8.2
Ibuprofen Capsule	223	7.8	7.8
Ibuprofen Tablet, Film Coated	223	7.8	7.8
Ibupfrofen	223	7.8	7.8
Ibuprofen Tablets Usp, 200Mg	223	7.8	7.8
Ibuprofen Oral	223	7.8	7.8
Ibuprofen Capsules 200 Mg	223	7.8	7.8
Ibuprofen 200 Mg	223	7.8	7.8
Ibuprofen 200Mg	223	7.8	7.8
Hydroxyzine	49	6.8	6.8
Fentanyl	94	6.4	6.4
Oxycodone And Acetaminophen Tablets	11	6.1	6.1
Ibuprofen	228	5.8	5.8
Meperidine Hydrochloride	8	5.7	5.7
Loperamide Hydrochloride	38	5.6	5.6
Morphine Sulfate	100	5.5	5.5
Methocarbamol Tablets	13	5.1	5.1
Cetirizine Hydrochloride Allergy	23	5.0	5.0
Cetirizine Hydrochloride Tablets	23	5.0	5.0
Fexofenadine Hcl	6	4.3	4.3
Lithium	16	4.2	4.2
Lithium Bromatum	16	4.2	4.2
Benzonatate	10	4.0	4.0
Acetaminophen And Codeine	6	3.2	3.2
Oxycodone And Acetaminophen	11	3.1	3.1
Miconazole Nitrate	4	3.0	3.0
Sodium Oxybate	30	3.0	3.0
Cariprazine	4	2.8	2.8
Relugolix	9	2.5	2.5
Brivaracetam	3	2.2	2.2
Agalsidase Beta	3	2.1	2.1
Dupilumab	78	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.