OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Ibuprofen Capsules 200 Mg

1,174 flagged reaction(s) · 990,869 total co-reports · max PRR 99.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Nsaid Exacerbated Respiratory Disease 172 99.8 99.9 signal
2 Anti-cyclic Citrullinated Peptide Antibody 287 79.7 79.8 signal
3 Deep Vein Thrombosis Postoperative 797 72.3 72.6 signal
4 Duodenal Ulcer Perforation 2,892 68.6 69.6 signal
5 C-reactive Protein 347 65.3 65.4 signal
6 Anti-cyclic Citrullinated Peptide Antibody Positive 2,632 62.0 62.8 signal
7 Lupus Vulgaris 431 59.8 60.0 signal
8 Muscle Injury 2,935 58.7 59.5 signal
9 Subcutaneous Drug Absorption Impaired 193 57.8 57.8 signal
10 Sleep Disorder Due To General Medical Condition, Insomnia Type 2,217 55.3 56.0 signal
11 Adjustment Disorder With Depressed Mood 689 54.7 54.9 signal
12 Swollen Joint Count Increased 1,011 50.5 50.7 signal
13 Aspirin-exacerbated Respiratory Disease 196 48.1 48.1 signal
14 Rheumatic Fever 1,258 42.5 42.8 signal
15 X-ray Abnormal 510 42.1 42.2 signal
16 Dislocation Of Vertebra 619 40.5 40.7 signal
17 Folliculitis 2,860 40.3 40.8 signal
18 Helicobacter Infection 2,811 40.0 40.6 signal
19 Cross Sensitivity Reaction 239 34.7 34.7 signal
20 Rheumatoid Factor Positive 1,431 34.7 34.9 signal
21 Facet Joint Syndrome 742 32.3 32.5 signal
22 Pemphigus 2,876 31.6 32.1 signal
23 Hand Deformity 2,789 28.5 28.8 signal
24 Retinitis 335 26.4 26.4 signal
25 C-reactive Protein Abnormal 1,230 24.9 25.1 signal
26 Pericarditis 3,109 24.1 24.4 signal
27 Enthesopathy 286 23.2 23.3 signal
28 Peripheral Venous Disease 702 22.4 22.5 signal
29 Synovitis 3,101 21.8 22.1 signal
30 Granuloma Skin 138 21.0 21.0 signal
31 Gastric Ulcer Perforation 199 19.5 19.5 signal
32 Chronic Kidney Disease-mineral And Bone Disorder 167 19.3 19.3 signal
33 Porphyria Acute 208 18.6 18.6 signal
34 Irritable Bowel Syndrome 3,158 18.2 18.5 signal
35 Seronegative Arthritis 160 17.4 17.4 signal
36 Renal Tubular Acidosis 290 16.0 16.0 signal
37 Glossodynia 2,868 15.4 15.6 signal
38 Fixed Eruption 214 15.2 15.2 signal
39 Obstructive Sleep Apnoea Syndrome 164 14.0 14.0 signal
40 Drug Tolerance Decreased 324 13.7 13.7 signal
41 Nephrogenic Anaemia 534 13.5 13.6 signal
42 Death Neonatal 157 13.5 13.5 signal
43 Lip Dry 1,012 13.3 13.4 signal
44 Tenosynovitis 306 13.0 13.1 signal
45 Blood Parathyroid Hormone Decreased 164 13.0 13.0 signal
46 Biliary Dyskinesia 186 12.7 12.8 signal
47 Cholecystitis Chronic 727 12.6 12.6 signal
48 Hyperparathyroidism Secondary 265 12.3 12.3 signal
49 Wound 2,830 11.9 12.0 signal
50 Impaired Healing 3,289 11.7 11.8 signal
51 Lip Oedema 423 11.6 11.6 signal
52 Grip Strength Decreased 852 11.3 11.4 signal
53 Rheumatoid Nodule 269 11.2 11.2 signal
54 Bone Erosion 342 11.2 11.2 signal
55 Contraindicated Product Administered 2,851 10.9 11.1 signal
56 Autoimmune Disorder 900 10.9 10.9 signal
57 Breast Cancer Stage Iii 605 10.9 10.9 signal
58 Bursitis 1,130 10.8 10.9 signal
59 Joint Range Of Motion Decreased 1,207 10.4 10.5 signal
60 Hypercholesterolaemia 855 10.3 10.3 signal
61 Maternal Exposure Timing Unspecified 332 10.3 10.3 signal
62 Analgesic Drug Level Increased 143 10.2 10.2 signal
63 Lower Respiratory Tract Infection 3,985 10.1 10.3 signal
64 Meningitis Aseptic 386 9.9 9.9 signal
65 Systemic Lupus Erythematosus 3,001 9.7 9.8 signal
66 Rebound Acid Hypersecretion 257 9.6 9.6 signal
67 Wound Infection 909 9.6 9.6 signal
68 Fibromyalgia 1,962 9.2 9.3 signal
69 Oligohydramnios 268 9.1 9.1 signal
70 Duodenal Ulcer Haemorrhage 221 8.7 8.7 signal
71 Peptic Ulcer 255 8.7 8.7 signal
72 Duodenal Ulcer 541 8.7 8.7 signal
73 Liver Injury 1,852 8.7 8.8 signal
74 Tubulointerstitial Nephritis 1,414 8.6 8.6 signal
75 Panniculitis 176 8.2 8.3 signal
76 Muscle Spasticity 904 8.2 8.3 signal
77 Exostosis 663 8.2 8.2 signal
78 Kounis Syndrome 163 8.1 8.1 signal
79 Gallbladder Injury 139 8.1 8.1 signal
80 Suspected Suicide 340 8.0 8.1 signal
81 Self-medication 288 7.9 7.9 signal
82 Blister 3,892 7.8 8.0 signal
83 Live Birth 577 7.8 7.8 signal
84 Exposure To Toxic Agent 223 7.8 7.8 signal
85 Gastritis Erosive 323 7.8 7.8 signal
86 Alanine Aminotransferase Abnormal 144 7.7 7.7 signal
87 Arthropathy 3,808 7.7 7.8 signal
88 Obesity 1,079 7.6 7.6 signal
89 Psoriatic Arthropathy 2,670 7.4 7.5 signal
90 Pustular Psoriasis 228 7.4 7.4 signal
91 Therapeutic Product Effect Decreased 2,921 7.4 7.5 signal
92 Red Blood Cell Sedimentation Rate Increased 717 7.2 7.3 signal
93 Ear Pain 1,229 7.1 7.1 signal
94 Angioedema 2,783 7.0 7.1 signal
95 Sciatica 1,000 7.0 7.1 signal
96 End Stage Renal Disease 1,155 7.0 7.0 signal
97 Plantar Fasciitis 210 7.0 7.0 signal
98 Night Sweats 2,008 7.0 7.0 signal
99 Toxic Epidermal Necrolysis 935 6.9 7.0 signal
100 Discomfort 3,743 6.9 7.0 signal
101 Renal Tubular Necrosis 606 6.9 6.9 signal
102 Stomatitis 3,614 6.6 6.7 signal
103 Walking Aid User 387 6.5 6.5 signal
104 Spondylitis 212 6.5 6.5 signal
105 Chronic Kidney Disease 4,452 6.5 6.6 signal
106 Multiple Drug Overdose Intentional 188 6.4 6.4 signal
107 Type 2 Diabetes Mellitus 1,942 6.4 6.4 signal
108 Intentional Overdose 3,640 6.3 6.4 signal
109 Gastric Ulcer 1,078 6.3 6.3 signal
110 Ulcer Haemorrhage 383 6.3 6.3 signal
111 Upper Gastrointestinal Haemorrhage 946 6.2 6.2 signal
112 Foot Deformity 594 5.9 5.9 signal
113 Lower Limb Fracture 1,021 5.9 5.9 signal
114 Hepatic Enzyme Increased 3,632 5.9 6.0 signal
115 Blepharospasm 329 5.9 5.9 signal
116 Infusion Related Reaction 3,469 5.8 5.9 signal
117 Ankylosing Spondylitis 684 5.8 5.8 signal
118 Gastric Ulcer Haemorrhage 292 5.8 5.8 signal
119 Joint Swelling 6,286 5.8 5.9 signal
120 Thrombophlebitis Superficial 156 5.6 5.6 signal
121 Pre-existing Condition Improved 319 5.6 5.6 signal
122 Rash Vesicular 241 5.5 5.5 signal
123 Swelling 4,635 5.5 5.6 signal
124 Prescribed Overdose 955 5.4 5.5 signal
125 Duodenitis 151 5.4 5.4 signal
126 Injury 3,473 5.4 5.5 signal
127 Melaena 1,079 5.4 5.4 signal
128 Osteoarthritis 2,065 5.4 5.4 signal
129 Sinusitis 4,976 5.3 5.4 signal
130 Body Temperature Increased 987 5.3 5.3 signal
131 Haematemesis 1,224 5.3 5.3 signal
132 Pulmonary Fibrosis 909 5.2 5.2 signal
133 Hip Arthroplasty 720 5.2 5.2 signal
134 Suicide Attempt 2,866 5.2 5.2 signal
135 Eye Injury 141 5.1 5.1 signal
136 Brain Natriuretic Peptide Increased 144 5.1 5.1 signal
137 Tongue Oedema 176 5.0 5.1 signal
138 Poisoning Deliberate 427 5.0 5.0 signal
139 Musculoskeletal Stiffness 3,957 5.0 5.0 signal
140 Metabolic Acidosis 1,411 4.9 4.9 signal
141 Blood Cholesterol Increased 2,060 4.8 4.9 signal
142 Functional Gastrointestinal Disorder 153 4.8 4.8 signal
143 Nail Disorder 382 4.8 4.8 signal
144 Laryngitis 476 4.8 4.8 signal
145 Acute Kidney Injury 6,622 4.8 4.9 signal
146 Gastrointestinal Disorder 3,841 4.8 4.8 signal
147 Breast Cancer Stage Ii 364 4.7 4.8 signal
148 Necrotising Fasciitis 152 4.7 4.7 signal
149 Ill-defined Disorder 2,609 4.7 4.7 signal
150 Acute Generalised Exanthematous Pustulosis 330 4.7 4.7 signal
151 Abdominal Tenderness 211 4.6 4.6 signal
152 Acute Hepatic Failure 571 4.6 4.6 signal
153 Stevens-johnson Syndrome 918 4.5 4.5 signal
154 Patent Ductus Arteriosus 164 4.5 4.5 signal
155 Periorbital Oedema 210 4.4 4.4 signal
156 Musculoskeletal Pain 2,136 4.4 4.5 signal
157 Product Administered To Patient Of Inappropriate Age 242 4.4 4.4 signal
158 C-reactive Protein Increased 1,455 4.4 4.4 signal
159 Rheumatoid Arthritis 4,523 4.4 4.4 signal
160 Hyperacusis 149 4.4 4.4 signal
161 Drug Intolerance 3,830 4.3 4.4 signal
162 Skin Necrosis 207 4.3 4.3 signal
163 Joint Dislocation 415 4.3 4.3 signal
164 Respiratory Disorder 1,173 4.3 4.3 signal
165 Lupus-like Syndrome 350 4.2 4.2 signal
166 Multiple Drug Overdose 195 4.2 4.2 signal
167 Hepatitis Acute 249 4.2 4.2 signal
168 Intervertebral Disc Disorder 165 4.2 4.2 signal
169 Cholecystitis Acute 217 4.2 4.2 signal
170 Drug Tolerance 194 4.2 4.2 signal
171 Spinal Osteoarthritis 336 4.1 4.1 signal
172 Sleep Disorder 2,656 4.1 4.2 signal
173 Flank Pain 355 4.1 4.1 signal
174 Joint Effusion 262 4.1 4.1 signal
175 Gastritis 987 4.1 4.1 signal
176 Hepatic Necrosis 142 4.1 4.1 signal
177 Gait Inability 1,233 4.1 4.1 signal
178 Peripheral Swelling 5,690 4.0 4.1 signal
179 Gallbladder Disorder 663 4.0 4.0 signal
180 Wheezing 2,176 4.0 4.0 signal
181 Tongue Disorder 268 4.0 4.0 signal
182 Tendonitis 567 4.0 4.0 signal
183 Contusion 3,495 4.0 4.0 signal
184 Ulcer 577 3.9 3.9 signal
185 Tenderness 377 3.9 3.9 signal
186 Oedema 1,954 3.9 4.0 signal
187 Mobility Decreased 2,556 3.9 3.9 signal
188 General Physical Health Deterioration 4,099 3.9 3.9 signal
189 Myositis 319 3.9 3.9 signal
190 Inflammation 1,822 3.9 3.9 signal
191 Gastric Haemorrhage 410 3.8 3.8 signal
192 Renal Injury 1,059 3.8 3.8 signal
193 Completed Suicide 2,962 3.8 3.9 signal
194 Face Oedema 590 3.8 3.8 signal
195 Eyelid Oedema 407 3.8 3.8 signal
196 Knee Arthroplasty 718 3.7 3.7 signal
197 Anhedonia 910 3.7 3.7 signal
198 Drug-induced Liver Injury 1,059 3.7 3.7 signal
199 Anaphylactic Reaction 1,858 3.7 3.7 signal
200 Drug Hypersensitivity 6,537 3.6 3.7 signal
201 Abdominal Discomfort 5,608 3.6 3.7 signal
202 Hypothermia 329 3.5 3.5 signal
203 Joint Stiffness 846 3.5 3.5 signal
204 Therapy Non-responder 1,433 3.5 3.5 signal
205 Uterine Perforation 275 3.5 3.5 signal
206 Urticaria 5,349 3.5 3.5 signal
207 Gastrointestinal Toxicity 151 3.5 3.5 signal
208 Road Traffic Accident 1,339 3.5 3.5 signal
209 Economic Problem 492 3.5 3.5 signal
210 Intervertebral Disc Degeneration 297 3.5 3.5 signal
211 Ear Infection 847 3.5 3.5 signal
212 Infection 4,598 3.4 3.5 signal
213 Oesophagitis 347 3.4 3.4 signal
214 Hypersensitivity 5,865 3.4 3.5 signal
215 Synovial Cyst 146 3.4 3.4 signal
216 Tendon Disorder 205 3.4 3.4 signal
217 Erythema Multiforme 291 3.4 3.4 signal
218 Nasopharyngitis 5,763 3.4 3.4 signal
219 Maternal Exposure During Pregnancy 2,746 3.4 3.4 signal
220 Acidosis 238 3.4 3.4 signal
221 Spinal Pain 364 3.4 3.4 signal
222 Hepatitis Cholestatic 186 3.4 3.4 signal
223 Sleep Apnoea Syndrome 590 3.3 3.3 signal
224 Confusional State 4,959 3.3 3.4 signal
225 Delirium 1,056 3.3 3.3 signal
226 Pregnancy 617 3.3 3.3 signal
227 Cholecystitis 361 3.3 3.3 signal
228 Foot Operation 149 3.3 3.3 signal
229 Sensation Of Foreign Body 251 3.2 3.2 signal
230 Iron Deficiency Anaemia 274 3.2 3.2 signal
231 Cholelithiasis 977 3.2 3.2 signal
232 Renal Cyst 237 3.2 3.2 signal
233 Umbilical Hernia 139 3.2 3.2 signal
234 Endometriosis 141 3.2 3.2 signal
235 Muscle Strain 255 3.2 3.2 signal
236 Product Administration Interrupted 226 3.2 3.2 signal
237 Ligament Sprain 290 3.2 3.2 signal
238 Hypertransaminasaemia 197 3.1 3.1 signal
239 Psychological Trauma 252 3.1 3.1 signal
240 Pharyngitis 359 3.1 3.1 signal
241 Migraine 2,718 3.1 3.1 signal
242 Abdominal Pain Upper 5,883 3.1 3.2 signal
243 Intervertebral Disc Protrusion 627 3.1 3.1 signal
244 Post-traumatic Stress Disorder 192 3.1 3.1 signal
245 Atrial Septal Defect 239 3.1 3.1 signal
246 Drug Eruption 499 3.1 3.1 signal
247 Ventricular Septal Defect 163 3.0 3.0 signal
248 Lung Disorder 1,384 3.0 3.1 signal
249 Renal Failure Acute 1,214 3.0 3.1 signal
250 Joint Injury 601 3.0 3.0 signal
251 Toxicity To Various Agents 4,681 3.0 3.1 signal
252 Hypercalcaemia 344 3.0 3.0 signal
253 Lip Swelling 924 3.0 3.0 signal
254 Vitamin D Deficiency 270 3.0 3.0 signal
255 Tooth Infection 365 3.0 3.0 signal
256 Electrocardiogram Qrs Complex Prolonged 141 3.0 3.0 signal
257 Deep Vein Thrombosis 1,795 3.0 3.0 signal
258 Hiatus Hernia 356 3.0 3.0 signal
259 Back Disorder 448 3.0 3.0 signal
260 Poisoning 345 2.9 2.9 signal
261 Hepatic Steatosis 508 2.9 2.9 signal
262 Neck Pain 1,527 2.9 3.0 signal
263 Liver Disorder 1,204 2.9 2.9 signal
264 Atelectasis 263 2.9 2.9 signal
265 Lymphoedema 187 2.9 2.9 signal
266 Osteopenia 409 2.9 2.9 signal
267 Polyuria 219 2.9 2.9 signal
268 Hyperventilation 155 2.9 2.9 signal
269 Tricuspid Valve Incompetence 211 2.9 2.9 signal
270 Renal Failure 3,568 2.9 2.9 signal
271 Pleurisy 159 2.9 2.9 signal
272 Gastrooesophageal Reflux Disease 2,134 2.9 2.9 signal
273 Arthralgia 10,921 2.8 2.9 signal
274 Hepatic Cirrhosis 491 2.8 2.8 signal
275 Labelled Drug-drug Interaction Medication Error 234 2.8 2.8 signal
276 Prescribed Underdose 522 2.8 2.8 signal
277 Intentional Self-injury 528 2.8 2.8 signal
278 Incorrect Route Of Product Administration 439 2.8 2.8 signal
279 Leukocytosis 467 2.8 2.8 signal
280 Nephropathy 242 2.8 2.8 signal
281 Abnormal Loss Of Weight 174 2.8 2.8 signal
282 Taste Disorder 515 2.8 2.8 signal
283 Dry Mouth 2,080 2.8 2.8 signal
284 Neuralgia 620 2.7 2.8 signal
285 Streptococcal Infection 142 2.7 2.7 signal
286 Oliguria 158 2.7 2.7 signal
287 Anuria 220 2.7 2.7 signal
288 Rash Maculo-papular 563 2.7 2.7 signal
289 Laryngeal Oedema 156 2.7 2.7 signal
290 Disability 500 2.7 2.7 signal
291 Hypoaesthesia 3,772 2.7 2.7 signal
292 Gastrointestinal Haemorrhage 2,116 2.7 2.7 signal
293 Seasonal Allergy 354 2.7 2.7 signal
294 Tooth Fracture 276 2.7 2.7 signal
295 Treatment Failure 2,053 2.7 2.7 signal
296 Nephrolithiasis 1,139 2.7 2.7 signal
297 Alopecia 4,882 2.7 2.7 signal
298 General Symptom 187 2.7 2.7 signal
299 Dermatitis Bullous 178 2.7 2.7 signal
300 Basal Cell Carcinoma 386 2.7 2.7 signal
301 Meniscus Injury 152 2.6 2.7 signal
302 Hyperaesthesia 204 2.6 2.6 signal
303 Vitamin D Decreased 211 2.6 2.6 signal
304 Pain 15,063 2.6 2.8 signal
305 Sinus Headache 146 2.6 2.6 signal
306 Rotator Cuff Syndrome 314 2.6 2.6 signal
307 Nephropathy Toxic 271 2.6 2.6 signal
308 Coagulopathy 404 2.6 2.6 signal
309 Faeces Discoloured 527 2.6 2.6 signal
310 Dyspepsia 2,381 2.6 2.6 signal
311 Congenital Anomaly 189 2.6 2.6 signal
312 Nerve Injury 270 2.6 2.6 signal
313 Prothrombin Time Prolonged 146 2.6 2.6 signal
314 Osteoporosis 994 2.6 2.6 signal
315 Arthritis 1,893 2.6 2.6 signal
316 Coronavirus Infection 160 2.6 2.6 signal
317 Infusion Site Swelling 147 2.6 2.6 signal
318 Obstructive Airways Disorder 266 2.6 2.6 signal
319 Musculoskeletal Chest Pain 369 2.6 2.6 signal
320 Drug Toxicity 329 2.6 2.6 signal
321 Sinus Tachycardia 337 2.6 2.6 signal
322 Weight Increased 5,293 2.5 2.6 signal
323 Major Depression 174 2.5 2.5 signal
324 Lower Gastrointestinal Haemorrhage 176 2.5 2.5 signal
325 Hyperlipidaemia 284 2.5 2.5 signal
326 Agranulocytosis 438 2.5 2.5 signal
327 Pharyngeal Swelling 226 2.5 2.5 signal
328 Intentional Product Use Issue 2,075 2.5 2.5 signal
329 Uterine Leiomyoma 173 2.5 2.5 signal
330 Upper Respiratory Tract Infection 1,088 2.5 2.5 signal
331 Medication Error 1,308 2.5 2.5 signal
332 Musculoskeletal Discomfort 405 2.5 2.5 signal
333 Electrocardiogram Abnormal 185 2.5 2.5 signal
334 Ovarian Cyst 236 2.5 2.5 signal
335 Gastrointestinal Pain 257 2.5 2.5 signal
336 Alanine Aminotransferase Increased 1,436 2.5 2.5 signal
337 Back Injury 252 2.5 2.5 signal
338 Groin Pain 205 2.5 2.5 signal
339 Diverticulum 167 2.5 2.5 signal
340 Hypokalaemia 1,062 2.5 2.5 signal
341 Weight Fluctuation 241 2.5 2.5 signal
342 Inguinal Hernia 141 2.5 2.5 signal
343 Amnesia 1,507 2.5 2.5 signal
344 Autoimmune Hepatitis 159 2.5 2.5 signal
345 Eosinophilia 401 2.5 2.5 signal
346 Carpal Tunnel Syndrome 322 2.5 2.5 signal
347 Jaundice 617 2.4 2.5 signal
348 Drug Screen Positive 180 2.4 2.4 signal
349 Tendon Pain 173 2.4 2.4 signal
350 Impaired Gastric Emptying 291 2.4 2.4 signal
351 Cholecystectomy 259 2.4 2.4 signal
352 Pyrexia 7,886 2.4 2.5 signal
353 Back Pain 5,290 2.4 2.5 signal
354 Sedation 593 2.4 2.4 signal
355 Shock 517 2.4 2.4 signal
356 Drug Reaction With Eosinophilia And Systemic Symptoms 578 2.4 2.4 signal
357 Circulatory Collapse 385 2.4 2.4 signal
358 Hepatomegaly 222 2.4 2.4 signal
359 Colitis Ischaemic 151 2.4 2.4 signal
360 Pelvic Pain 408 2.4 2.4 signal
361 Sinus Congestion 302 2.4 2.4 signal
362 Multiple Allergies 174 2.4 2.4 signal
363 Abdominal Pain 5,137 2.4 2.4 signal
364 Toothache 399 2.4 2.4 signal
365 Tooth Abscess 225 2.4 2.4 signal
366 Liver Function Test Increased 469 2.4 2.4 signal
367 Quality Of Life Decreased 295 2.4 2.4 signal
368 Nightmare 762 2.3 2.4 signal
369 Shock Haemorrhagic 178 2.3 2.3 signal
370 Loss Of Personal Independence In Daily Activities 1,041 2.3 2.4 signal
371 Paraesthesia 3,452 2.3 2.4 signal
372 Head Discomfort 385 2.3 2.3 signal
373 Tachycardia 1,938 2.3 2.3 signal
374 Splenomegaly 255 2.3 2.3 signal
375 Chest Pain 4,041 2.3 2.4 signal
376 Conjunctivitis 400 2.3 2.3 signal
377 Body Temperature Decreased 216 2.3 2.3 signal
378 Nerve Compression 200 2.3 2.3 signal
379 Transaminases Increased 480 2.3 2.3 signal
380 Tachypnoea 292 2.3 2.3 signal
381 Somnambulism 142 2.3 2.3 signal
382 Product Prescribing Error 510 2.3 2.3 signal
383 Depression 4,921 2.3 2.3 signal
384 Anxiety 6,118 2.3 2.3 signal
385 Pulmonary Embolism 2,043 2.3 2.3 signal
386 Muscle Tightness 346 2.3 2.3 signal
387 Haematochezia 1,178 2.3 2.3 signal
388 Pulmonary Congestion 283 2.3 2.3 signal
389 Photophobia 399 2.3 2.3 signal
390 Pulmonary Toxicity 150 2.3 2.3 signal
391 Ankle Fracture 331 2.3 2.3 signal
392 Rhinitis 172 2.3 2.3 signal
393 Vomiting 9,978 2.3 2.3 signal
394 Abdominal Pain Lower 539 2.3 2.3 signal
395 Substance Abuse 173 2.3 2.3 signal
396 Coma 1,009 2.3 2.3 signal
397 Encephalitis 146 2.3 2.3 signal
398 Lactic Acidosis 679 2.3 2.3 signal
399 Bronchospasm 302 2.3 2.3 signal
400 Haemodynamic Instability 158 2.3 2.3 signal
401 Pruritus 7,917 2.2 2.3 signal
402 Hepatotoxicity 464 2.2 2.2 signal
403 Acute Respiratory Distress Syndrome 369 2.2 2.2 signal
404 Sleep Disorder Due To A General Medical Condition 337 2.2 2.2 signal
405 Rash 9,034 2.2 2.3 signal
406 Exposure During Pregnancy 1,295 2.2 2.2 signal
407 Aspartate Aminotransferase Increased 1,103 2.2 2.2 signal
408 Secretion Discharge 256 2.2 2.2 signal
409 Chromaturia 467 2.2 2.2 signal
410 Feeling Drunk 154 2.2 2.2 signal
411 Lymphocyte Count Decreased 365 2.2 2.2 signal
412 Large Intestine Polyp 143 2.2 2.2 signal
413 Rash Pruritic 1,112 2.2 2.2 signal
414 Obsessive-compulsive Disorder 166 2.2 2.2 signal
415 Haemorrhoids 400 2.2 2.2 signal
416 Insomnia 5,452 2.2 2.2 signal
417 Hysterectomy 176 2.2 2.2 signal
418 Muscular Weakness 2,315 2.2 2.2 signal
419 Accidental Exposure To Product By Child 139 2.2 2.2 signal
420 Asthma 2,281 2.2 2.2 signal
421 Muscle Twitching 470 2.2 2.2 signal
422 Oedema Peripheral 2,472 2.2 2.2 signal
423 Condition Aggravated 6,102 2.2 2.2 signal
424 Rectal Haemorrhage 869 2.2 2.2 signal
425 Pancreatitis Acute 448 2.1 2.1 signal
426 Dysstasia 588 2.1 2.1 signal
427 Skin Infection 224 2.1 2.1 signal
428 Pain In Extremity 5,923 2.1 2.2 signal
429 Hypertension 4,241 2.1 2.2 signal
430 Scar 343 2.1 2.1 signal
431 Gait Disturbance 3,831 2.1 2.2 signal
432 Brain Injury 200 2.1 2.1 signal
433 Ataxia 237 2.1 2.1 signal
434 Depressed Level Of Consciousness 785 2.1 2.1 signal
435 Swollen Tongue 617 2.1 2.1 signal
436 Respiratory Depression 241 2.1 2.1 signal
437 Coordination Abnormal 276 2.1 2.1 signal
438 Urine Output Decreased 172 2.1 2.1 signal
439 Lymphadenopathy 695 2.1 2.1 signal
440 Restless Legs Syndrome 357 2.1 2.1 signal
441 Blood Urea Increased 330 2.1 2.1 signal
442 Cyst 242 2.1 2.1 signal
443 Tinnitus 895 2.1 2.1 signal
444 Dental Caries 214 2.1 2.1 signal
445 Epilepsy 590 2.1 2.1 signal
446 Food Allergy 146 2.1 2.1 signal
447 Sensory Loss 156 2.1 2.1 signal
448 Headache 12,093 2.1 2.1 signal
449 Drug Interaction 3,063 2.1 2.1 signal
450 Hyperkalaemia 672 2.1 2.1 signal
451 Skin Ulcer 497 2.1 2.1 signal
452 Foot Fracture 365 2.0 2.1 signal
453 Swelling Face 1,248 2.0 2.1 signal
454 Cardiomegaly 238 2.0 2.0 signal
455 Hepatic Cytolysis 234 2.0 2.0 signal
456 Impaired Quality Of Life 273 2.0 2.0 signal
457 Unresponsive To Stimuli 488 2.0 2.0 signal
458 Spinal Disorder 180 2.0 2.0 signal
459 Musculoskeletal Disorder 362 2.0 2.0 signal
460 Feeling Hot 1,159 2.0 2.0 signal
461 Therapeutic Product Effect Incomplete 1,335 2.0 2.0 signal
462 Kidney Infection 370 2.0 2.0 signal
463 Cardiac Murmur 164 2.0 2.0 signal
464 Decreased Appetite 4,361 2.0 2.0 signal
465 Pneumothorax 298 2.0 2.0 signal
466 Infusion Site Pain 240 2.0 2.0 signal
467 Blood Calcium Decreased 212 2.0 2.0 signal
468 Haematoma 488 2.0 2.0 signal
469 Apnoea 147 2.0 2.0 signal
470 Ear Discomfort 192 2.0 2.0 signal
471 Feeling Cold 523 2.0 2.0 signal
472 Mitral Valve Incompetence 212 2.0 2.0 no signal
473 Respiratory Tract Congestion 297 2.0 2.0 no signal
474 Throat Tightness 504 2.0 2.0 no signal
475 Paraesthesia Oral 268 2.0 2.0 no signal
476 Limb Discomfort 577 2.0 2.0 no signal
477 Fatigue 14,479 2.0 2.1 no signal
478 Dyspnoea 10,530 2.0 2.0 no signal
479 Multiple Organ Dysfunction Syndrome 518 2.0 2.0 no signal
480 Hepatic Failure 560 2.0 2.0 no signal
481 Micturition Urgency 210 2.0 2.0 no signal
482 Tendon Rupture 229 2.0 2.0 no signal
483 Myocarditis 209 2.0 2.0 no signal
484 Initial Insomnia 188 2.0 2.0 no signal
485 Skin Laceration 199 2.0 2.0 no signal
486 Dyspnoea Exertional 691 2.0 2.0 no signal
487 Hyperhidrosis 2,371 2.0 2.0 no signal
488 Pyelonephritis 158 2.0 2.0 no signal
489 Muscle Spasms 3,363 2.0 2.0 no signal
490 Blood Iron Decreased 216 2.0 2.0 no signal
491 Somnolence 3,676 2.0 2.0 no signal
492 Facial Pain 163 1.9 1.9 no signal
493 Nocturia 221 1.9 1.9 no signal
494 Cellulitis 920 1.9 1.9 no signal
495 Brain Oedema 230 1.9 1.9 no signal
496 Fear 493 1.9 1.9 no signal
497 Dysuria 668 1.9 1.9 no signal
498 Pharyngitis Streptococcal 196 1.9 1.9 no signal
499 Infusion Site Erythema 150 1.9 1.9 no signal
500 Rib Fracture 371 1.9 1.9 no signal
501 Influenza Like Illness 1,490 1.9 1.9 no signal
502 Neutrophil Count Increased 185 1.9 1.9 no signal
503 Lung Infiltration 160 1.9 1.9 no signal
504 Skin Lesion 489 1.9 1.9 no signal
505 Hypoaesthesia Oral 270 1.9 1.9 no signal
506 Aspiration 194 1.9 1.9 no signal
507 Cold Sweat 316 1.9 1.9 no signal
508 White Blood Cell Count Increased 689 1.9 1.9 no signal
509 Hypokinesia 260 1.9 1.9 no signal
510 Blood Pressure Systolic Increased 350 1.9 1.9 no signal
511 Small Intestinal Obstruction 219 1.9 1.9 no signal
512 Muscle Atrophy 224 1.9 1.9 no signal
513 Bipolar Disorder 195 1.9 1.9 no signal
514 Lethargy 1,017 1.9 1.9 no signal
515 Urinary Incontinence 523 1.9 1.9 no signal
516 Gastroenteritis 257 1.9 1.9 no signal
517 Mouth Ulceration 370 1.9 1.9 no signal
518 Memory Impairment 2,414 1.9 1.9 no signal
519 Oropharyngeal Pain 1,624 1.9 1.9 no signal
520 Haematocrit Decreased 350 1.9 1.9 no signal
521 Temperature Intolerance 179 1.9 1.9 no signal
522 Restlessness 642 1.9 1.9 no signal
523 Pruritus Generalised 384 1.9 1.9 no signal
524 Mydriasis 224 1.9 1.9 no signal
525 Disturbance In Attention 942 1.9 1.9 no signal
526 Anal Incontinence 155 1.9 1.9 no signal
527 Chest Discomfort 1,775 1.9 1.9 no signal
528 Emotional Distress 2,114 1.9 1.9 no signal
529 Bone Disorder 319 1.8 1.9 no signal
530 Personality Change 162 1.8 1.8 no signal
531 Uveitis 234 1.8 1.8 no signal
532 Petechiae 180 1.8 1.8 no signal
533 Bladder Disorder 172 1.8 1.8 no signal
534 Decreased Activity 185 1.8 1.8 no signal
535 Respiratory Tract Infection 448 1.8 1.8 no signal
536 Sensory Disturbance 277 1.8 1.8 no signal
537 Nausea 13,515 1.8 1.9 no signal
538 Panic Attack 624 1.8 1.8 no signal
539 Coronary Artery Disease 521 1.8 1.8 no signal
540 Mental Status Changes 474 1.8 1.8 no signal
541 Asthenia 6,397 1.8 1.8 no signal
542 Poor Quality Sleep 364 1.8 1.8 no signal
543 Gamma-glutamyltransferase Increased 377 1.8 1.8 no signal
544 Drug Abuse 1,417 1.8 1.8 no signal
545 Nasal Congestion 991 1.8 1.8 no signal
546 Glomerular Filtration Rate Decreased 205 1.8 1.8 no signal
547 Hepatitis 433 1.8 1.8 no signal
548 Dermatitis Contact 192 1.8 1.8 no signal
549 Agitation 1,244 1.8 1.8 no signal
550 Chills 1,980 1.8 1.8 no signal
551 Stress 1,210 1.8 1.8 no signal
552 Impaired Work Ability 360 1.8 1.8 no signal
553 Intentional Product Misuse 1,455 1.8 1.8 no signal
554 Hepatocellular Injury 238 1.8 1.8 no signal
555 Eye Swelling 618 1.8 1.8 no signal
556 Inflammatory Bowel Disease 164 1.8 1.8 no signal
557 Blood Alkaline Phosphatase Increased 414 1.8 1.8 no signal
558 Supraventricular Tachycardia 159 1.8 1.8 no signal
559 Menorrhagia 331 1.8 1.8 no signal
560 Photosensitivity Reaction 273 1.8 1.8 no signal
561 Dysarthria 623 1.8 1.8 no signal
562 Oral Herpes 322 1.8 1.8 no signal
563 Eating Disorder 353 1.8 1.8 no signal
564 Pallor 450 1.8 1.8 no signal
565 Blood Creatinine Increased 1,076 1.8 1.8 no signal
566 Proteinuria 310 1.7 1.8 no signal
567 Throat Irritation 735 1.7 1.8 no signal
568 Respiratory Arrest 457 1.7 1.8 no signal
569 Diverticulitis 454 1.7 1.8 no signal
570 Electrolyte Imbalance 189 1.7 1.7 no signal
571 Anaphylactic Shock 421 1.7 1.8 no signal
572 Dizziness 8,178 1.7 1.8 no signal
573 Tooth Disorder 367 1.7 1.7 no signal
574 Bronchitis 1,219 1.7 1.7 no signal
575 Hunger 220 1.7 1.7 no signal
576 Syncope 1,637 1.7 1.7 no signal
577 Polyneuropathy 194 1.7 1.7 no signal
578 Purpura 144 1.7 1.7 no signal
579 Respiratory Distress 449 1.7 1.7 no signal
580 Pharyngeal Oedema 253 1.7 1.7 no signal
581 Oral Discomfort 225 1.7 1.7 no signal
582 Cholestasis 308 1.7 1.7 no signal
583 Optic Neuritis 147 1.7 1.7 no signal
584 Inadequate Analgesia 138 1.7 1.7 no signal
585 Aphasia 485 1.7 1.7 no signal
586 Hemiparesis 273 1.7 1.7 no signal
587 Product Use Issue 2,993 1.7 1.7 no signal
588 Suicidal Ideation 1,466 1.7 1.7 no signal
589 Thirst 285 1.7 1.7 no signal
590 Dysmenorrhoea 209 1.7 1.7 no signal
591 Sputum Discoloured 151 1.7 1.7 no signal
592 Peripheral Coldness 220 1.7 1.7 no signal
593 Hot Flush 1,203 1.7 1.7 no signal
594 Breast Pain 170 1.7 1.7 no signal
595 Cardio-respiratory Arrest 671 1.7 1.7 no signal
596 Pulmonary Mass 237 1.7 1.7 no signal
597 Depressed Mood 838 1.7 1.7 no signal
598 Arteriosclerosis 150 1.7 1.7 no signal
599 Liver Function Test Abnormal 465 1.7 1.7 no signal
600 Gastric Disorder 553 1.7 1.7 no signal
601 Incontinence 168 1.7 1.7 no signal
602 Hypotonia 159 1.7 1.7 no signal
603 Mental Disorder 688 1.7 1.7 no signal
604 Oropharyngeal Discomfort 141 1.7 1.7 no signal
605 Disorientation 626 1.7 1.7 no signal
606 Post Procedural Haemorrhage 184 1.7 1.7 no signal
607 Renal Pain 166 1.7 1.7 no signal
608 Paranoia 272 1.7 1.7 no signal
609 Viral Infection 521 1.7 1.7 no signal
610 Apathy 227 1.7 1.7 no signal
611 Insurance Issue 232 1.7 1.7 no signal
612 Bone Pain 910 1.7 1.7 no signal
613 Overdose 3,357 1.6 1.7 no signal
614 Palpitations 1,812 1.6 1.7 no signal
615 Serotonin Syndrome 296 1.6 1.6 no signal
616 Balance Disorder 1,337 1.6 1.6 no signal
617 Increased Tendency To Bruise 142 1.6 1.6 no signal
618 Ventricular Extrasystoles 160 1.6 1.6 no signal
619 Dysphonia 898 1.6 1.6 no signal
620 Generalised Tonic-clonic Seizure 251 1.6 1.6 no signal
621 Accidental Overdose 559 1.6 1.6 no signal
622 Vertigo 932 1.6 1.6 no signal
623 Weight Decreased 4,258 1.6 1.6 no signal
624 Dermatitis Allergic 190 1.6 1.6 no signal
625 Movement Disorder 491 1.6 1.6 no signal
626 Myalgia 2,582 1.6 1.6 no signal
627 Gout 272 1.6 1.6 no signal
628 Motor Dysfunction 153 1.6 1.6 no signal
629 Hyponatraemia 849 1.6 1.6 no signal
630 Diarrhoea 9,706 1.6 1.6 no signal
631 Hypotension 3,019 1.6 1.6 no signal
632 Pain In Jaw 424 1.6 1.6 no signal
633 Appendicitis 139 1.6 1.6 no signal
634 Retching 318 1.6 1.6 no signal
635 Adverse Drug Reaction 1,334 1.6 1.6 no signal
636 Pancreatitis 789 1.6 1.6 no signal
637 Product Administration Error 297 1.6 1.6 no signal
638 Blood Bilirubin Increased 403 1.6 1.6 no signal
639 Osteomyelitis 269 1.6 1.6 no signal
640 Dysphagia 1,407 1.6 1.6 no signal
641 Limb Injury 402 1.6 1.6 no signal
642 Presyncope 359 1.6 1.6 no signal
643 Hair Colour Changes 186 1.6 1.6 no signal
644 Haematuria 507 1.6 1.6 no signal
645 Sinus Bradycardia 143 1.6 1.6 no signal
646 Product Use In Unapproved Indication 3,604 1.6 1.6 no signal
647 Crying 538 1.6 1.6 no signal
648 Mood Swings 470 1.6 1.6 no signal
649 Drug Level Increased 244 1.6 1.6 no signal
650 Gingival Bleeding 201 1.6 1.6 no signal
651 Psoriasis 1,916 1.6 1.6 no signal
652 Heart Rate Irregular 333 1.6 1.6 no signal
653 Constipation 3,170 1.6 1.6 no signal
654 Oral Pain 329 1.6 1.6 no signal
655 Rhinorrhoea 942 1.6 1.6 no signal
656 Foetal Exposure During Pregnancy 1,185 1.5 1.6 no signal
657 Candida Infection 243 1.5 1.5 no signal
658 Blood Sodium Decreased 273 1.5 1.5 no signal
659 Hypophagia 368 1.5 1.5 no signal
660 Therapeutic Response Unexpected 653 1.5 1.5 no signal
661 Blood Potassium Decreased 436 1.5 1.5 no signal
662 Hypoxia 508 1.5 1.5 no signal
663 Anaemia 2,764 1.5 1.5 no signal
664 Cough 4,049 1.5 1.5 no signal
665 Urinary Tract Infection 2,457 1.5 1.5 no signal
666 Rash Macular 503 1.5 1.5 no signal
667 Sinus Disorder 286 1.5 1.5 no signal
668 Oral Candidiasis 187 1.5 1.5 no signal
669 Flushing 1,467 1.5 1.5 no signal
670 Hyperbilirubinaemia 148 1.5 1.5 no signal
671 Eye Infection 161 1.5 1.5 no signal
672 Localised Infection 347 1.5 1.5 no signal
673 Psychomotor Hyperactivity 239 1.5 1.5 no signal
674 Vasculitis 167 1.5 1.5 no signal
675 Multiple Sclerosis Relapse 990 1.5 1.5 no signal
676 Acute Respiratory Failure 274 1.5 1.5 no signal
677 Rash Erythematous 670 1.5 1.5 no signal
678 Scratch 148 1.5 1.5 no signal
679 Scab 162 1.5 1.5 no signal
680 Madarosis 167 1.5 1.5 no signal
681 Rash Papular 320 1.5 1.5 no signal
682 Hepatic Encephalopathy 133 1.5 1.5 no signal
683 Bradycardia 755 1.5 1.5 no signal
684 Myocardial Ischaemia 163 1.5 1.5 no signal
685 Pollakiuria 591 1.5 1.5 no signal
686 Wrist Fracture 170 1.5 1.5 no signal
687 Euphoric Mood 146 1.5 1.5 no signal
688 Eye Pain 782 1.5 1.5 no signal
689 Diplopia 367 1.5 1.5 no signal
690 Procedural Pain 390 1.5 1.5 no signal
691 Rhabdomyolysis 585 1.5 1.5 no signal
692 Hypersomnia 402 1.5 1.5 no signal
693 Burning Sensation 984 1.5 1.5 no signal
694 Emphysema 142 1.5 1.5 no signal
695 Urinary Retention 466 1.5 1.5 no signal
696 Renal Impairment 1,167 1.5 1.5 no signal
697 Haemoglobin Decreased 1,434 1.5 1.5 no signal
698 Middle Insomnia 259 1.5 1.5 no signal
699 Immunodeficiency 205 1.5 1.5 no signal
700 Influenza 1,555 1.5 1.5 no signal
701 Feeding Disorder 277 1.5 1.5 no signal
702 Cystitis 444 1.5 1.5 no signal
703 Hallucination, Visual 291 1.5 1.5 no signal
704 Loss Of Consciousness 1,776 1.5 1.5 no signal
705 Cyanosis 218 1.5 1.5 no signal
706 Productive Cough 652 1.5 1.5 no signal
707 Bone Density Decreased 436 1.5 1.5 no signal
708 Vitreous Floaters 134 1.5 1.5 no signal
709 Blood Urine Present 262 1.5 1.5 no signal
710 Dehydration 1,834 1.5 1.5 no signal
711 Laceration 131 1.5 1.5 no signal
712 Blood Pressure Fluctuation 330 1.5 1.5 no signal
713 Haemoptysis 383 1.5 1.5 no signal
714 Affect Lability 132 1.4 1.4 no signal
715 Angina Pectoris 393 1.4 1.4 no signal
716 Adverse Event 1,254 1.4 1.4 no signal
717 Malaise 5,970 1.4 1.5 no signal
718 Local Swelling 240 1.4 1.4 no signal
719 Fall 4,510 1.4 1.4 no signal
720 Intestinal Perforation 152 1.4 1.4 no signal
721 Multiple Sclerosis 650 1.4 1.4 no signal
722 Colitis 509 1.4 1.4 no signal
723 Thinking Abnormal 253 1.4 1.4 no signal
724 Cardiac Arrest 1,119 1.4 1.4 no signal
725 Cognitive Disorder 627 1.4 1.4 no signal
726 Urosepsis 124 1.4 1.4 no signal
727 Vision Blurred 1,837 1.4 1.4 no signal
728 Hypothyroidism 428 1.4 1.4 no signal
729 Erythema 2,757 1.4 1.4 no signal
730 Hair Texture Abnormal 181 1.4 1.4 no signal
731 Ileus 165 1.4 1.4 no signal
732 Acute Myocardial Infarction 397 1.4 1.4 no signal
733 Heart Rate Increased 1,327 1.4 1.4 no signal
734 Multiple Fractures 222 1.4 1.4 no signal
735 Abscess 213 1.4 1.4 no signal
736 Sickle Cell Anaemia With Crisis 211 1.4 1.4 no signal
737 Encephalopathy 327 1.4 1.4 no signal
738 Diarrhoea Haemorrhagic 125 1.4 1.4 no signal
739 Hypertensive Crisis 149 1.4 1.4 no signal
740 Mass 187 1.4 1.4 no signal
741 Gastroenteritis Viral 241 1.4 1.4 no signal
742 Skin Haemorrhage 192 1.4 1.4 no signal
743 Dermatitis 275 1.4 1.4 no signal
744 Therapeutic Response Decreased 799 1.4 1.4 no signal
745 Sopor 177 1.4 1.4 no signal
746 Staphylococcal Infection 438 1.4 1.4 no signal
747 Hernia 254 1.4 1.4 no signal
748 Laboratory Test Abnormal 389 1.4 1.4 no signal
749 Impaired Driving Ability 150 1.4 1.4 no signal
750 Blood Lactate Dehydrogenase Increased 210 1.4 1.4 no signal
751 Fluid Retention 667 1.4 1.4 no signal
752 Eye Disorder 430 1.4 1.4 no signal
753 Drug Ineffective For Unapproved Indication 731 1.4 1.4 no signal
754 Tooth Loss 273 1.4 1.4 no signal
755 Immune System Disorder 172 1.4 1.4 no signal
756 Leukopenia 652 1.4 1.4 no signal
757 Feeling Abnormal 3,139 1.4 1.4 no signal
758 Oxygen Saturation Decreased 726 1.4 1.4 no signal
759 Mucosal Inflammation 339 1.4 1.4 no signal
760 Pneumonia 4,203 1.4 1.4 no signal
761 Epistaxis 971 1.4 1.4 no signal
762 Activities Of Daily Living Impaired 260 1.4 1.4 no signal
763 Irritability 779 1.4 1.4 no signal
764 Eye Discharge 132 1.4 1.4 no signal
765 Spinal Operation 156 1.4 1.4 no signal
766 Malnutrition 143 1.4 1.4 no signal
767 Skin Disorder 428 1.4 1.4 no signal
768 Sneezing 287 1.4 1.4 no signal
769 Dysgeusia 956 1.4 1.4 no signal
770 Adrenal Insufficiency 153 1.4 1.4 no signal
771 Bone Loss 194 1.4 1.4 no signal
772 Hyperglycaemia 464 1.4 1.4 no signal
773 Abdominal Distension 1,326 1.4 1.4 no signal
774 Expired Product Administered 423 1.4 1.4 no signal
775 Coeliac Disease 125 1.4 1.4 no signal
776 Pleural Effusion 775 1.3 1.4 no signal
777 Seizure 1,458 1.3 1.3 no signal
778 Dizziness Postural 122 1.3 1.3 no signal
779 Anger 431 1.3 1.3 no signal
780 Tremor 2,101 1.3 1.3 no signal
781 Pulmonary Hypertension 264 1.3 1.3 no signal
782 Brain Fog 184 1.3 1.3 no signal
783 Myoclonus 150 1.3 1.3 no signal
784 Electrocardiogram Qt Prolonged 452 1.3 1.3 no signal
785 Pericardial Effusion 289 1.3 1.3 no signal
786 Bacterial Infection 232 1.3 1.3 no signal
787 Ventricular Fibrillation 139 1.3 1.3 no signal
788 Visual Impairment 1,531 1.3 1.3 no signal
789 Ocular Discomfort 135 1.3 1.3 no signal
790 International Normalised Ratio Increased 357 1.3 1.3 no signal
791 Inappropriate Antidiuretic Hormone Secretion 126 1.3 1.3 no signal
792 Knee Operation 120 1.3 1.3 no signal
793 Blood Triglycerides Increased 219 1.3 1.3 no signal
794 Vaginal Discharge 124 1.3 1.3 no signal
795 Bedridden 162 1.3 1.3 no signal
796 Blood Pressure Increased 1,888 1.3 1.3 no signal
797 Platelet Count Increased 161 1.3 1.3 no signal
798 Frequent Bowel Movements 331 1.3 1.3 no signal
799 Central Nervous System Lesion 170 1.3 1.3 no signal
800 Fungal Infection 409 1.3 1.3 no signal
801 Covid-19 2,173 1.3 1.3 no signal
802 Respiratory Failure 896 1.3 1.3 no signal
803 Atrial Fibrillation 1,197 1.3 1.3 no signal
804 Accident 146 1.3 1.3 no signal
805 Skin Discolouration 563 1.3 1.3 no signal
806 Heart Rate Decreased 429 1.3 1.3 no signal
807 Sepsis 1,354 1.3 1.3 no signal
808 Tooth Extraction 151 1.3 1.3 no signal
809 Surgery 702 1.3 1.3 no signal
810 Salivary Hypersecretion 121 1.3 1.3 no signal
811 Hereditary Angioedema 127 1.3 1.3 no signal
812 Rash Generalised 317 1.3 1.3 no signal
813 Grand Mal Convulsion 113 1.3 1.3 no signal
814 Subarachnoid Haemorrhage 123 1.3 1.3 no signal
815 Intentional Dose Omission 329 1.3 1.3 no signal
816 Feeling Jittery 229 1.3 1.3 no signal
817 Hallucination 898 1.3 1.3 no signal
818 Septic Shock 517 1.3 1.3 no signal
819 Drug Ineffective 15,713 1.3 1.3 no signal
820 Altered State Of Consciousness 257 1.3 1.3 no signal
821 Dry Throat 121 1.3 1.3 no signal
822 Lacrimation Increased 356 1.3 1.3 no signal
823 Dry Eye 576 1.3 1.3 no signal
824 Toxic Skin Eruption 120 1.3 1.3 no signal
825 Speech Disorder 621 1.3 1.3 no signal
826 Neuropathy Peripheral 1,120 1.3 1.3 no signal
827 Status Epilepticus 134 1.3 1.3 no signal
828 Sluggishness 120 1.3 1.3 no signal
829 Covid-19 Pneumonia 140 1.2 1.2 no signal
830 Decreased Immune Responsiveness 115 1.2 1.2 no signal
831 Withdrawal Syndrome 496 1.2 1.2 no signal
832 Abortion Spontaneous 472 1.2 1.2 no signal
833 Renal Disorder 547 1.2 1.2 no signal
834 Red Blood Cell Count Decreased 334 1.2 1.2 no signal
835 Post Procedural Complication 224 1.2 1.2 no signal
836 Cardiogenic Shock 166 1.2 1.2 no signal
837 Cardiomyopathy 172 1.2 1.2 no signal
838 Aggression 582 1.2 1.2 no signal
839 Nodule 151 1.2 1.2 no signal
840 Osteonecrosis Of Jaw 288 1.2 1.2 no signal
841 Mood Altered 314 1.2 1.2 no signal
842 Orthostatic Hypotension 201 1.2 1.2 no signal
843 Blood Pressure Abnormal 227 1.2 1.2 no signal
844 Flatulence 648 1.2 1.2 no signal
845 Blood Pressure Decreased 758 1.2 1.2 no signal
846 Arrhythmia 543 1.2 1.2 no signal
847 Skin Fissures 214 1.2 1.2 no signal
848 Aphonia 158 1.2 1.2 no signal
849 Abnormal Dreams 314 1.2 1.2 no signal
850 Herpes Zoster 650 1.2 1.2 no signal
851 Product Dose Omission In Error 303 1.2 1.2 no signal
852 Therapeutic Response Shortened 359 1.2 1.2 no signal
853 Embedded Device 111 1.2 1.2 no signal
854 Pulmonary Oedema 505 1.2 1.2 no signal
855 Pneumonia Aspiration 280 1.2 1.2 no signal
856 Adverse Reaction 149 1.2 1.2 no signal
857 Paralysis 160 1.2 1.2 no signal
858 Ejection Fraction Decreased 173 1.2 1.2 no signal
859 Colitis Ulcerative 495 1.2 1.2 no signal
860 Hypocalcaemia 209 1.2 1.2 no signal
861 Hyperthyroidism 160 1.2 1.2 no signal
862 Pneumonitis 299 1.2 1.2 no signal
863 Hallucination, Auditory 176 1.2 1.2 no signal
864 Treatment Noncompliance 598 1.2 1.2 no signal
865 Illness 1,105 1.2 1.2 no signal
866 Generalised Oedema 135 1.2 1.2 no signal
867 Upper Limb Fracture 219 1.2 1.2 no signal
868 Malignant Melanoma 146 1.2 1.2 no signal
869 Mental Impairment 263 1.1 1.1 no signal
870 Disseminated Intravascular Coagulation 153 1.1 1.1 no signal
871 Spinal Fracture 216 1.1 1.1 no signal
872 Emotional Disorder 336 1.1 1.1 no signal
873 Drug Effect Less Than Expected 152 1.1 1.1 no signal
874 Abasia 270 1.1 1.1 no signal
875 Transient Ischaemic Attack 365 1.1 1.1 no signal
876 Dyskinesia 435 1.1 1.1 no signal
877 Bacteraemia 126 1.1 1.1 no signal
878 Body Height Decreased 115 1.1 1.1 no signal
879 Cardiovascular Disorder 272 1.1 1.1 no signal
880 Blood Creatine Phosphokinase Increased 311 1.1 1.1 no signal
881 Eyelid Ptosis 108 1.1 1.1 no signal
882 Deafness 278 1.1 1.1 no signal
883 Ageusia 265 1.1 1.1 no signal
884 Product Odour Abnormal 110 1.1 1.1 no signal
885 Deformity 99 1.1 1.1 no signal
886 Clostridium Difficile Colitis 112 1.1 1.1 no signal
887 Metastases To Central Nervous System 135 1.1 1.1 no signal
888 Skin Reaction 148 1.1 1.1 no signal
889 Eructation 200 1.1 1.1 no signal
890 Libido Decreased 130 1.1 1.1 no signal
891 Head Injury 331 1.1 1.1 no signal
892 Hospice Care 103 1.1 1.1 no signal
893 Nervousness 549 1.1 1.1 no signal
894 Pancytopenia 582 1.1 1.1 no signal
895 Subdural Haematoma 150 1.1 1.1 no signal
896 Fracture 197 1.1 1.1 no signal
897 Chronic Obstructive Pulmonary Disease 542 1.1 1.1 no signal
898 Eczema 522 1.1 1.1 no signal
899 Thrombocytopenia 1,156 1.1 1.1 no signal
900 Hypoglycaemia 502 1.1 1.1 no signal
901 Lymphopenia 145 1.1 1.1 no signal
902 Sexual Dysfunction 120 1.1 1.1 no signal
903 Disease Recurrence 489 1.1 1.1 no signal
904 Poor Venous Access 105 1.1 1.1 no signal
905 Diabetes Mellitus 775 1.1 1.1 no signal
906 Thrombosis 815 1.1 1.1 no signal
907 Genital Haemorrhage 130 1.1 1.1 no signal
908 Cataract 595 1.1 1.1 no signal
909 Metastases To Bone 164 1.1 1.1 no signal
910 Anosmia 145 1.1 1.1 no signal
911 Intentional Drug Misuse 211 1.1 1.1 no signal
912 Therapy Partial Responder 149 1.0 1.0 no signal
913 Off Label Use 8,567 1.0 1.0 no signal
914 Squamous Cell Carcinoma 93 1.0 1.0 no signal
915 Coronary Artery Occlusion 136 1.0 1.0 no signal
916 Vaginal Haemorrhage 420 1.0 1.0 no signal
917 Incorrect Product Administration Duration 199 1.0 1.0 no signal
918 Retinal Detachment 90 1.0 1.0 no signal
919 Haemorrhage 1,023 1.0 1.0 no signal
920 Delusion 151 1.0 1.0 no signal
921 Erectile Dysfunction 251 1.0 1.0 no signal
922 Convulsion 561 1.0 1.0 no signal
923 Multi-organ Failure 169 1.0 1.0 no signal
924 Blood Potassium Increased 156 1.0 1.0 no signal
925 Blindness Unilateral 135 1.0 1.0 no signal
926 Choking 186 1.0 1.0 no signal
927 White Blood Cell Count Decreased 1,038 1.0 1.0 no signal
928 Drug Effect Incomplete 352 1.0 1.0 no signal
929 Abnormal Behaviour 381 1.0 1.0 no signal
930 Blood Thyroid Stimulating Hormone Increased 88 1.0 1.0 no signal
931 Product Taste Abnormal 128 1.0 1.0 no signal
932 Injection Site Bruising 745 1.0 1.0 no signal
933 Skin Exfoliation 779 1.0 1.0 no signal
934 Ascites 275 1.0 1.0 no signal
935 Injection Site Haematoma 136 1.0 1.0 no signal
936 Unevaluable Event 701 1.0 1.0 no signal
937 Hypomagnesaemia 128 1.0 1.0 no signal
938 Inappropriate Schedule Of Product Administration 1,623 1.0 1.0 no signal
939 Injection Site Reaction 629 1.0 1.0 no signal
940 Thyroid Disorder 141 1.0 1.0 no signal
941 Muscle Rigidity 109 1.0 1.0 no signal
942 Premature Baby 274 1.0 1.0 no signal
943 Increased Appetite 170 1.0 1.0 no signal
944 Sudden Death 96 0.9 0.9 no signal
945 Nervous System Disorder 281 0.9 0.9 no signal
946 Sars-cov-2 Test Positive 119 0.9 0.9 no signal
947 Therapy Cessation 455 0.9 0.9 no signal
948 Blood Test Abnormal 125 0.9 0.9 no signal
949 Peritonitis 184 0.9 0.9 no signal
950 Mania 146 0.9 0.9 no signal
951 Ventricular Tachycardia 147 0.9 0.9 no signal
952 Psychotic Disorder 262 0.9 0.9 no signal
953 Cytokine Release Syndrome 168 0.9 0.9 no signal
954 Product Dose Omission 583 0.9 0.9 no signal
955 Neoplasm 101 0.9 0.9 no signal
956 Dry Skin 1,153 0.9 0.9 no signal
957 Osteonecrosis 290 0.9 0.9 no signal
958 Drug Prescribing Error 170 0.9 0.9 no signal
959 Product Dose Omission Issue 2,468 0.9 0.9 no signal
960 Injection Site Induration 112 0.9 0.9 no signal
961 Full Blood Count Abnormal 91 0.9 0.9 no signal
962 Injection Site Warmth 176 0.9 0.9 no signal
963 Injection Site Rash 258 0.9 0.9 no signal
964 Metastases To Liver 149 0.9 0.9 no signal
965 Pain Of Skin 229 0.9 0.9 no signal
966 Transfusion 89 0.9 0.9 no signal
967 Lung Infection 132 0.9 0.9 no signal
968 Device Related Infection 129 0.9 0.9 no signal
969 Product Substitution Issue 479 0.9 0.9 no signal
970 Diabetes Mellitus Inadequate Control 147 0.9 0.9 no signal
971 Internal Haemorrhage 95 0.9 0.9 no signal
972 Injection Site Erythema 1,020 0.9 0.9 no signal
973 Prostatic Specific Antigen Increased 114 0.9 0.9 no signal
974 Extra Dose Administered 328 0.9 0.9 no signal
975 Injection Site Pruritus 542 0.9 0.9 no signal
976 Ischaemic Stroke 145 0.9 0.9 no signal
977 Caesarean Section 95 0.9 0.9 no signal
978 Drug Effect Decreased 441 0.9 0.9 no signal
979 Hypoacusis 345 0.8 0.8 no signal
980 Incorrect Drug Administration Duration 229 0.8 0.8 no signal
981 No Therapeutic Response 99 0.8 0.8 no signal
982 Complication Associated With Device 105 0.8 0.8 no signal
983 Haemorrhage Intracranial 119 0.8 0.8 no signal
984 Incorrect Dose Administered 1,783 0.8 0.8 no signal
985 Visual Acuity Reduced 265 0.8 0.8 no signal
986 Anorexia 103 0.8 0.8 no signal
987 Hepatic Function Abnormal 292 0.8 0.8 no signal
988 Amenorrhoea 131 0.8 0.8 no signal
989 Injection Site Nodule 86 0.8 0.8 no signal
990 Dermatitis Atopic 390 0.8 0.8 no signal
991 Intestinal Obstruction 289 0.8 0.8 no signal
992 Metastases To Lung 89 0.8 0.8 no signal
993 Pulmonary Thrombosis 84 0.8 0.8 no signal
994 Cerebral Haemorrhage 275 0.8 0.8 no signal
995 Neutrophil Count Decreased 311 0.8 0.8 no signal
996 Ocular Hyperaemia 358 0.8 0.8 no signal
997 Eye Inflammation 72 0.8 0.8 no signal
998 Glaucoma 147 0.8 0.8 no signal
999 Injection Site Swelling 576 0.8 0.8 no signal
1000 Injection Site Discolouration 94 0.8 0.8 no signal
1001 Product Physical Issue 151 0.8 0.8 no signal
1002 Febrile Neutropenia 501 0.8 0.8 no signal
1003 Hip Fracture 242 0.8 0.8 no signal
1004 Femur Fracture 234 0.8 0.8 no signal
1005 Abortion Induced 71 0.8 0.8 no signal
1006 Palmar-plantar Erythrodysaesthesia Syndrome 176 0.8 0.8 no signal
1007 Premature Delivery 119 0.8 0.8 no signal
1008 Underdose 543 0.8 0.8 no signal
1009 Diabetic Ketoacidosis 178 0.8 0.8 no signal
1010 Injection Site Urticaria 180 0.8 0.8 no signal
1011 Eye Pruritus 244 0.8 0.8 no signal
1012 Drug Administration Error 230 0.8 0.8 no signal
1013 Cardiac Disorder 689 0.8 0.8 no signal
1014 Neoplasm Progression 256 0.8 0.8 no signal
1015 Blood Count Abnormal 112 0.8 0.8 no signal
1016 Device Dislocation 315 0.8 0.8 no signal
1017 Injection Site Mass 266 0.8 0.8 no signal
1018 Dialysis 101 0.7 0.7 no signal
1019 Schizophrenia 86 0.7 0.7 no signal
1020 Platelet Count Decreased 752 0.7 0.7 no signal
1021 Cerebrovascular Accident 1,197 0.7 0.7 no signal
1022 Injection Site Irritation 89 0.7 0.7 no signal
1023 Inappropriate Schedule Of Drug Administration 507 0.7 0.7 no signal
1024 Full Blood Count Decreased 141 0.7 0.7 no signal
1025 Skin Burning Sensation 497 0.7 0.7 no signal
1026 Skin Irritation 316 0.7 0.7 no signal
1027 Eye Haemorrhage 92 0.7 0.7 no signal
1028 Rebound Effect 78 0.7 0.7 no signal
1029 Product Use Complaint 106 0.7 0.7 no signal
1030 Neutropenia 926 0.7 0.7 no signal
1031 Cardiac Failure 549 0.7 0.7 no signal
1032 Hepatitis C 83 0.7 0.7 no signal
1033 Clostridium Difficile Infection 147 0.7 0.7 no signal
1034 Product Prescribing Issue 138 0.7 0.7 no signal
1035 Therapy Interrupted 466 0.7 0.7 no signal
1036 Product Quality Issue 907 0.7 0.7 no signal
1037 Eye Irritation 375 0.7 0.7 no signal
1038 Myocardial Infarction 1,181 0.7 0.7 no signal
1039 Metrorrhagia 116 0.7 0.7 no signal
1040 Disease Progression 790 0.7 0.7 no signal
1041 Colon Cancer 100 0.7 0.7 no signal
1042 Akathisia 91 0.7 0.7 no signal
1043 Drug Withdrawal Syndrome 591 0.7 0.7 no signal
1044 Menstruation Irregular 176 0.7 0.7 no signal
1045 Cerebral Infarction 162 0.7 0.7 no signal
1046 Injection Site Pain 2,007 0.7 0.7 no signal
1047 Cardiac Failure Congestive 534 0.7 0.7 no signal
1048 Neuroleptic Malignant Syndrome 78 0.7 0.7 no signal
1049 Drug Level Decreased 67 0.7 0.7 no signal
1050 Therapy Change 63 0.7 0.7 no signal
1051 Blood Glucose Abnormal 120 0.7 0.7 no signal
1052 Breast Cancer Metastatic 69 0.7 0.7 no signal
1053 Blindness 261 0.7 0.7 no signal
1054 Neoplasm Malignant 427 0.7 0.7 no signal
1055 Lymphoma 99 0.7 0.7 no signal
1056 Dystonia 124 0.7 0.7 no signal
1057 Drug Dose Omission 1,062 0.7 0.7 no signal
1058 Pulmonary Arterial Hypertension 92 0.7 0.7 no signal
1059 Complication Of Device Insertion 116 0.7 0.7 no signal
1060 Device Occlusion 87 0.7 0.7 no signal
1061 Fistula 70 0.7 0.7 no signal
1062 Abnormal Weight Gain 77 0.6 0.6 no signal
1063 Device Failure 93 0.6 0.6 no signal
1064 Product Availability Issue 137 0.6 0.6 no signal
1065 Acne 464 0.6 0.6 no signal
1066 Hospitalisation 913 0.6 0.6 no signal
1067 Wrong Technique In Drug Usage Process 220 0.6 0.6 no signal
1068 Macular Degeneration 71 0.6 0.6 no signal
1069 Device Issue 515 0.6 0.6 no signal
1070 Complication Of Device Removal 100 0.6 0.6 no signal
1071 Tuberculosis 75 0.6 0.6 no signal
1072 Poor Quality Product Administered 59 0.6 0.6 no signal
1073 Injection Site Haemorrhage 453 0.6 0.6 no signal
1074 Skin Cancer 122 0.6 0.6 no signal
1075 Brain Neoplasm 52 0.6 0.6 no signal
1076 Menstruation Delayed 57 0.6 0.6 no signal
1077 Glycosylated Haemoglobin Increased 138 0.6 0.6 no signal
1078 Posterior Reversible Encephalopathy Syndrome 52 0.6 0.6 no signal
1079 Parkinsonism 53 0.6 0.6 no signal
1080 Injection Site Discomfort 56 0.6 0.6 no signal
1081 Neurotoxicity 94 0.6 0.6 no signal
1082 Inability To Afford Medication 53 0.6 0.6 no signal
1083 Dementia 148 0.6 0.6 no signal
1084 Malignant Neoplasm Progression 537 0.6 0.6 no signal
1085 Drug Administered At Inappropriate Site 56 0.6 0.6 no signal
1086 Blood Glucose Fluctuation 56 0.5 0.5 no signal
1087 Blood Glucose Increased 959 0.5 0.5 no signal
1088 Blood Glucose Decreased 241 0.5 0.5 no signal
1089 Product Adhesion Issue 174 0.5 0.5 no signal
1090 Intraocular Pressure Increased 63 0.5 0.5 no signal
1091 Device Breakage 191 0.5 0.5 no signal
1092 Drug Effective For Unapproved Indication 142 0.5 0.5 no signal
1093 Product Packaging Issue 45 0.5 0.5 no signal
1094 Needle Issue 136 0.5 0.5 no signal
1095 Bone Marrow Failure 97 0.5 0.5 no signal
1096 Tardive Dyskinesia 132 0.5 0.5 no signal
1097 Device Malfunction 311 0.5 0.5 no signal
1098 Thrombotic Microangiopathy 44 0.5 0.5 no signal
1099 Accidental Exposure To Product 449 0.5 0.5 no signal
1100 Unintended Pregnancy 47 0.5 0.5 no signal
1101 Drug Dependence 727 0.5 0.5 no signal
1102 Extrapyramidal Disorder 112 0.5 0.5 no signal
1103 Skeletal Injury 46 0.5 0.5 no signal
1104 Application Site Pain 96 0.5 0.5 no signal
1105 Drug Exposure During Pregnancy 150 0.5 0.5 no signal
1106 Meningioma 64 0.5 0.5 no signal
1107 Pharmaceutical Product Complaint 111 0.4 0.4 no signal
1108 Ovarian Cancer 39 0.4 0.4 no signal
1109 Fluid Overload 62 0.4 0.4 no signal
1110 No Adverse Event 744 0.4 0.4 no signal
1111 Wrong Technique In Product Usage Process 826 0.4 0.4 no signal
1112 Gastric Cancer 103 0.4 0.4 no signal
1113 Product Administered At Inappropriate Site 72 0.4 0.4 no signal
1114 Product Dispensing Error 84 0.4 0.4 no signal
1115 Application Site Erythema 101 0.4 0.4 no signal
1116 Leukaemia 36 0.4 0.4 no signal
1117 Interstitial Lung Disease 183 0.4 0.4 no signal
1118 Plasma Cell Myeloma 146 0.4 0.4 no signal
1119 Application Site Rash 51 0.4 0.4 no signal
1120 Death 3,148 0.4 0.4 no signal
1121 Device Use Issue 61 0.4 0.4 no signal
1122 Pneumocystis Jirovecii Pneumonia 35 0.4 0.4 no signal
1123 Thyroid Cancer 42 0.4 0.4 no signal
1124 Injection Site Extravasation 43 0.4 0.4 no signal
1125 Lung Neoplasm Malignant 142 0.4 0.4 no signal
1126 Acute Myeloid Leukaemia 52 0.4 0.4 no signal
1127 Product Preparation Error 67 0.3 0.3 no signal
1128 Application Site Pruritus 72 0.3 0.3 no signal
1129 Drug Dispensing Error 49 0.3 0.3 no signal
1130 Device Defective 51 0.3 0.3 no signal
1131 Incorrect Product Storage 42 0.3 0.3 no signal
1132 Myelodysplastic Syndrome 45 0.3 0.3 no signal
1133 Cytopenia 37 0.3 0.3 no signal
1134 Breast Cancer 288 0.3 0.3 no signal
1135 Breast Cancer Female 82 0.3 0.3 no signal
1136 Drug Resistance 77 0.3 0.3 no signal
1137 Application Site Irritation 37 0.3 0.3 no signal
1138 Exposure Via Skin Contact 67 0.3 0.3 no signal
1139 Injury Associated With Device 57 0.3 0.3 no signal
1140 Circumstance Or Information Capable Of Leading To Medication Error 93 0.3 0.3 no signal
1141 Device Deployment Issue 33 0.3 0.3 no signal
1142 Device Leakage 116 0.3 0.3 no signal
1143 Myelosuppression 91 0.3 0.3 no signal
1144 Cytomegalovirus Infection 44 0.3 0.3 no signal
1145 Haematotoxicity 24 0.3 0.3 no signal
1146 Device Expulsion 155 0.2 0.2 no signal
1147 Drug Withdrawal Syndrome Neonatal 35 0.2 0.2 no signal
1148 Product Complaint 58 0.2 0.2 no signal
1149 Prostate Cancer 186 0.2 0.2 no signal
1150 Device Difficult To Use 149 0.2 0.2 no signal
1151 Device Delivery System Issue 57 0.2 0.2 no signal
1152 Wrong Technique In Device Usage Process 96 0.2 0.2 no signal
1153 Incorrect Dose Administered By Device 53 0.2 0.2 no signal
1154 Syringe Issue 35 0.2 0.2 no signal
1155 Product Storage Error 168 0.2 0.2 no signal
1156 Device Use Error 66 0.2 0.2 no signal
1157 Incorrect Route Of Drug Administration 69 0.2 0.2 no signal
1158 Device Mechanical Issue 24 0.2 0.2 no signal
1159 Accidental Underdose 27 0.2 0.2 no signal
1160 Gynaecomastia 56 0.2 0.2 no signal
1161 Pancreatic Carcinoma 51 0.2 0.2 no signal
1162 Product Packaging Quantity Issue 19 0.2 0.2 no signal
1163 Dependence 96 0.2 0.2 no signal
1164 Breast Cancer Stage I 15 0.2 0.2 no signal
1165 Hepatic Cancer 36 0.2 0.2 no signal
1166 Oesophageal Carcinoma 36 0.1 0.1 no signal
1167 Drug Dose Omission By Device 86 0.1 0.1 no signal
1168 Unintentional Medical Device Removal 13 0.1 0.1 no signal
1169 Renal Cancer 53 0.1 0.1 no signal
1170 Peritonitis Bacterial 11 0.1 0.1 no signal
1171 Gastrointestinal Carcinoma 9 0.1 0.1 no signal
1172 Bladder Cancer 55 0.1 0.1 no signal
1173 Device Adhesion Issue 13 0.1 0.1 no signal
1174 Colorectal Cancer 4 0.0 0.0 no signal