Reaction

Intervertebral Disc Space Narrowing reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 794 reports · 38 co-occurring drugs

As of the last recalculation, Intervertebral Disc Space Narrowing appears in 794 FAERS reports alongside 38 co-occurring drug terms. The strongest observed disproportionality signal is CHLORHEXIDINE GLUCONATE (PRR 64.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Chlorhexidine Gluconate	22	64.9	65.0
Valganciclovir	24	34.4	34.4
Valganciclovir Hydrochloride	24	34.4	34.4
Exemestane	27	34.2	34.2
Amphotericin B	16	34.1	34.2
Tamsulosin Hydrochloride	23	30.4	30.4
Sodium Bicarbonate	26	30.3	30.3
Sodium Bicarbonate Injection,	26	30.3	30.3
Tolterodine Tartrate	10	29.6	29.6
Leflunomide	102	29.2	29.2
Meperidine Hydrochloride	9	25.9	25.9
Clindamycin	27	25.8	25.8
Candesartan Cilexetil	25	25.7	25.7
Clindamycin Phosphate	30	24.4	24.5
Bicalutamide	13	22.7	22.7
Darbepoetin Alfa	44	22.6	22.6
Fulvestrant	27	22.1	22.2
Torsemide	26	21.2	21.3
Thalidomide	28	20.7	20.7
Mycophenolic Acid	24	20.2	20.3
Goserelin	10	19.8	19.8
Desoximetasone	14	19.6	19.6
Melphalan	16	18.8	18.8
Doxazosin Mesylate	25	18.7	18.7
Erythropoietin	14	18.2	18.2
Melphalan Hydrochloride	17	18.1	18.2
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	6	17.6	17.6
Doxazosin	17	16.3	16.3
Loratadine And Pseudoephedrine Sulfate	4	13.2	13.3
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	5	13.1	13.1
Minoxidil Foam 5% (Womens)	16	13.0	13.0
Abatacept	61	12.4	12.4
Emtricitabine And Tenofovir Alafenamide	5	11.6	11.6
Golimumab	35	11.1	11.1
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	7	10.2	10.2
Lapatinib	6	10.2	10.2
Minoxidil	16	9.5	9.5
Paricalcitol	4	7.5	7.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.