Upcoming vaccines

• Applications under review come from the regulators. The EU rows are the European Medicines Agency's monthly list of applications under evaluation by its human medicines committee; the Canadian rows are Health Canada's list of new drug submissions under review, filtered to the rows whose own therapeutic-area field reads “Vaccines”. Both are copied, with the date each list was published. Neither list gives a developer's internal candidate code, so a link from an application to a candidate tracked here is a judgement someone made once and recorded, with the published wording it rests on shown beside it. An application with no link is still listed: it is pending whether or not this site tracks the product.
• Where the records come from. One file, vaccine_pipeline_data.json, built by fetch_vaccine_pipeline_from_ctgov.py from the ClinicalTrials.gov API v2 (interventional BIOLOGICAL vaccine trials, grouped per candidate) plus hand-curated rows for FDA CBER licences and company filing announcements. This page is generated from that file by build_upcoming_vaccines.py and adds nothing of its own: a date that is not in the file is not on the page.
• Two kinds of date, never mixed. regulator-confirmed a regulator published it. company estimate a company announced it. registry estimate a sponsor's estimated completion date in the trial registry. Only the first is a fact about a regulator's action.
• Registry phase is not regulatory status. A candidate's stage here is read from its most advanced active trial. A licensed vaccine whose only running studies are early-phase therefore reads as early-phase. Check the licence sections, not the phase, for what is approved.
• 19 records are left out as stale. When every registered trial under a candidate has finished, the candidate stops coming back from the registry query. Its page stays published and the full dashboard still lists it, but its dates were last confirmed at an earlier fetch, so it is excluded from every section above rather than presented as current.
• Absence means absence of a record, not absence of a programme. Trials that are not registered, or are registered outside ClinicalTrials.gov, do not appear; nor do regulatory actions outside the jurisdictions the curated rows cover. Chinese, Indian and Russian registries are not ingested.
• No recommendations. Nothing here says a candidate will be approved, will work, or should be taken. For licensed vaccines and their reported adverse events, use the vaccine matrix and the individual guides.

The full filterable table of all 335 candidate records, including discontinued programmes, is at the vaccine pipeline dashboard; each candidate also has its own page. Viruses and what exists against them are in the Virus Navigator, and the gap matrix lists targets with no vaccine and no antiviral at /virus-navigator/gaps.html.