Drug

Alendronate Sodium

1,313 flagged reaction(s) · 1,019,086 total co-reports · max PRR 4,997.2

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Intramedullary Rod Insertion	1,972	4,997.2	5,097.4	signal
2	Low Turnover Osteopathy	3,765	3,302.6	3,431.3	signal
3	Open Reduction Of Fracture	1,018	1,645.3	1,662.2	signal
4	Oral Torus	214	1,464.2	1,467.3	signal
5	Anti-cyclic Citrullinated Peptide Antibody Positive	5,368	669.0	706.8	signal
6	Anti-cyclic Citrullinated Peptide Antibody	494	614.5	617.6	signal
7	Swollen Joint Count Increased	2,291	596.8	610.7	signal
8	Rheumatic Fever	3,184	579.4	598.3	signal
9	Pemphigus	9,017	569.0	625.1	signal
10	Deep Vein Thrombosis Postoperative	1,368	494.4	501.2	signal
11	Duodenal Ulcer Perforation	4,964	446.5	469.7	signal
12	Lupus Vulgaris	797	432.8	436.2	signal
13	Fracture Nonunion	911	418.3	422.2	signal
14	Removal Of Internal Fixation	114	371.4	371.8	signal
15	C-reactive Protein	576	369.5	371.6	signal
16	Facet Joint Syndrome	1,998	368.1	375.6	signal
17	Anaemia Postoperative	829	363.6	366.6	signal
18	Rheumatoid Factor Positive	3,539	336.9	349.2	signal
19	Grip Strength	142	335.0	335.5	signal
20	Granuloma Skin	484	297.4	298.9	signal
21	Red Blood Cell Sedimentation Rate	162	286.7	287.1	signal
22	Internal Fixation Of Fracture	318	263.2	264.0	signal
23	Hand Deformity	7,215	259.9	280.0	signal
24	Adjustment Disorder With Depressed Mood	1,052	230.2	232.6	signal
25	Swollen Joint Count	127	224.7	225.0	signal
26	Fracture Delayed Union	439	223.6	224.6	signal
27	Helicobacter Infection	4,968	200.2	210.6	signal
28	Dislocation Of Vertebra	1,035	183.0	184.9	signal
29	X-ray Abnormal	771	159.7	160.9	signal
30	Muscle Injury	3,521	157.8	163.5	signal
31	Retinitis	672	141.3	142.3	signal
32	Sleep Disorder Due To General Medical Condition, Insomnia Type	2,559	138.4	142.0	signal
33	Blood Parathyroid Hormone Decreased	590	137.3	138.1	signal
34	Stress Fracture	2,142	136.6	139.5	signal
35	Folliculitis	4,010	133.1	138.6	signal
36	Pulmonary Vasculitis	204	131.7	131.9	signal
37	Subcutaneous Drug Absorption Impaired	210	131.4	131.7	signal
38	Glossodynia	8,381	125.7	137.1	signal
39	Femur Fracture	11,361	120.9	136.3	signal
40	Peripheral Venous Disease	1,436	117.6	119.3	signal
41	Pericarditis	5,968	116.9	124.2	signal
42	Synovitis	6,427	115.9	123.7	signal
43	Fracture Displacement	153	113.0	113.1	signal
44	Total Lung Capacity Abnormal	127	104.7	104.8	signal
45	Pubis Fracture	228	96.3	96.5	signal
46	C-reactive Protein Abnormal	1,968	92.7	94.6	signal
47	Limb Asymmetry	232	90.2	90.4	signal
48	Seronegative Arthritis	334	88.6	88.9	signal
49	Bone Graft	279	88.1	88.3	signal
50	Patellofemoral Pain Syndrome	151	86.6	86.7	signal
51	Resorption Bone Increased	238	85.6	85.8	signal
52	Atypical Femur Fracture	806	83.0	83.6	signal
53	Drug Tolerance Decreased	792	82.4	83.1	signal
54	Fibrocystic Breast Disease	208	80.9	81.0	signal
55	Hypercholesterolaemia	2,655	80.3	82.4	signal
56	Carotid Bruit	107	79.3	79.4	signal
57	Alveolar Osteitis	117	79.0	79.1	signal
58	Calcium Deficiency	347	75.9	76.1	signal
59	Medical Device Removal	458	75.4	75.8	signal
60	Dental Fistula	111	75.4	75.5	signal
61	Systemic Lupus Erythematosus	9,315	74.7	82.2	signal
62	Bursitis	3,087	71.8	74.1	signal
63	Spondylolisthesis	442	71.0	71.3	signal
64	Wound	6,974	69.9	75.1	signal
65	Panniculitis	593	68.1	68.5	signal
66	Atrophic Vulvovaginitis	175	66.0	66.1	signal
67	Breast Cancer Stage Iii	1,496	63.2	64.2	signal
68	Lumbar Radiculopathy	269	62.5	62.6	signal
69	Oral Cavity Fistula	113	61.7	61.8	signal
70	Spirometry Abnormal	134	61.7	61.8	signal
71	Bone Erosion	801	61.0	61.5	signal
72	Porphyria Acute	295	56.7	56.9	signal
73	Contraindicated Product Administered	6,435	56.6	60.4	signal
74	Periodontal Disease	300	56.5	56.7	signal
75	Rheumatoid Nodule	592	56.3	56.7	signal
76	Mycotic Allergy	178	55.9	56.0	signal
77	Tenosynovitis Stenosans	118	55.8	55.9	signal
78	Cerumen Impaction	192	54.9	55.0	signal
79	Kyphosis	369	54.8	55.0	signal
80	Reversible Airways Obstruction	107	54.8	54.8	signal
81	Arthroscopy	141	53.9	54.0	signal
82	Lip Dry	1,830	53.6	54.5	signal
83	Vertebral Foraminal Stenosis	167	52.8	52.9	signal
84	Onychomadesis	838	52.7	53.2	signal
85	Ulna Fracture	195	51.0	51.1	signal
86	Irritable Bowel Syndrome	4,184	50.8	53.0	signal
87	Stress Urinary Incontinence	212	50.6	50.7	signal
88	Osteogenesis Imperfecta	111	48.5	48.5	signal
89	Mite Allergy	117	46.8	46.9	signal
90	Bunion	132	46.2	46.2	signal
91	Grip Strength Decreased	1,585	46.1	46.9	signal
92	Atypical Fracture	111	46.1	46.2	signal
93	Tonsillectomy	302	46.0	46.1	signal
94	Onychomycosis	789	45.8	46.2	signal
95	Joint Range Of Motion Decreased	2,377	45.1	46.2	signal
96	Cystocele	150	43.8	43.9	signal
97	Impaired Healing	5,651	43.4	45.9	signal
98	Venous Insufficiency	122	41.7	41.8	signal
99	Neuritis	256	41.6	41.7	signal
100	Wound Infection	1,776	40.7	41.4	signal
101	Temporomandibular Joint Syndrome	443	40.7	40.9	signal
102	Lumbar Spinal Stenosis	476	40.4	40.6	signal
103	Anaemia Of Chronic Disease	144	39.5	39.6	signal
104	Live Birth	1,313	39.0	39.5	signal
105	Exostosis	1,432	38.8	39.3	signal
106	Debridement	120	38.7	38.7	signal
107	Spinal Osteoarthritis	1,380	38.6	39.1	signal
108	Antineutrophil Cytoplasmic Antibody Positive	113	38.3	38.3	signal
109	Radius Fracture	373	38.1	38.2	signal
110	Gingival Infection	124	37.5	37.6	signal
111	Fibromyalgia	3,658	37.0	38.3	signal
112	Arthropathy	8,317	36.5	39.7	signal
113	Tonsillar Disorder	168	36.4	36.4	signal
114	Vascular Calcification	158	36.0	36.0	signal
115	Breast Calcifications	118	35.9	36.0	signal
116	Blepharospasm	899	35.3	35.6	signal
117	Autoimmune Disorder	1,386	35.3	35.8	signal
118	Enthesopathy	228	35.2	35.3	signal
119	Oral Infection	564	35.1	35.3	signal
120	Mitral Valve Prolapse	236	34.4	34.4	signal
121	Fractured Sacrum	172	33.7	33.7	signal
122	Osteoarthritis	5,845	33.3	35.3	signal
123	Colonic Polyp	229	33.0	33.1	signal
124	Spinal Laminectomy	133	32.8	32.9	signal
125	Jaw Disorder	745	32.5	32.7	signal
126	Hip Arthroplasty	1,999	31.6	32.2	signal
127	Haemorrhagic Anaemia	573	30.7	30.9	signal
128	Liver Injury	3,104	30.7	31.6	signal
129	Abscess Jaw	134	30.5	30.5	signal
130	Periodontitis	271	30.2	30.3	signal
131	Bone Disorder	2,310	30.0	30.6	signal
132	Hyperlipidaemia	1,477	29.3	29.7	signal
133	Jaw Fracture	266	29.2	29.2	signal
134	Dust Allergy	118	29.0	29.1	signal
135	Colon Adenoma	122	29.0	29.1	signal
136	Vitamin D Deficiency	1,191	29.0	29.3	signal
137	Intervertebral Disc Degeneration	1,134	28.9	29.2	signal
138	Pathological Fracture	618	28.9	29.0	signal
139	Joint Destruction	190	28.8	28.9	signal
140	Sciatica	1,904	28.4	29.0	signal
141	Type 2 Diabetes Mellitus	4,054	28.4	29.6	signal
142	Amaurosis Fugax	127	28.1	28.1	signal
143	Seborrhoeic Keratosis	174	28.1	28.1	signal
144	Eosinophilic Granulomatosis With Polyangiitis	237	27.7	27.8	signal
145	Fibula Fracture	338	27.5	27.6	signal
146	Nail Disorder	991	26.8	27.1	signal
147	Carpal Tunnel Decompression	119	26.8	26.8	signal
148	Bone Cyst	107	26.8	26.8	signal
149	Loose Tooth	366	26.6	26.7	signal
150	Tenosynovitis	313	26.6	26.7	signal
151	Death Neonatal	155	26.4	26.4	signal
152	Bronchial Secretion Retention	142	26.4	26.4	signal
153	Osteopenia	1,705	26.2	26.6	signal
154	Scoliosis	693	26.2	26.3	signal
155	Red Blood Cell Sedimentation Rate Increased	1,226	25.9	26.2	signal
156	Obesity	1,762	25.9	26.3	signal
157	Pulmonary Fibrosis	2,093	25.6	26.1	signal
158	Fistula Discharge	139	25.6	25.6	signal
159	Infusion Related Reaction	7,163	25.3	27.2	signal
160	Gingival Disorder	419	25.3	25.4	signal
161	Meniscus Lesion	152	25.2	25.2	signal
162	Finger Deformity	515	24.8	24.9	signal
163	Osteonecrosis	3,515	24.7	25.6	signal
164	Foot Deformity	1,165	24.4	24.7	signal
165	Essential Hypertension	269	24.1	24.2	signal
166	Appendix Disorder	147	24.1	24.2	signal
167	Conjunctivitis Allergic	151	24.0	24.0	signal
168	Osteonecrosis Of Jaw	2,549	23.7	24.3	signal
169	Acute Sinusitis	176	23.7	23.8	signal
170	Blood Cholesterol Increased	4,748	23.6	24.7	signal
171	Dental Caries	1,124	23.6	23.8	signal
172	Appendicectomy	361	23.5	23.6	signal
173	Skin Necrosis	521	23.2	23.3	signal
174	Maternal Exposure Timing Unspecified	372	23.1	23.2	signal
175	Dental Implantation	163	23.1	23.2	signal
176	Psoriatic Arthropathy	4,013	23.1	24.0	signal
177	Infusion Site Reaction	286	22.7	22.8	signal
178	Spinal Column Stenosis	471	22.7	22.8	signal
179	Osteoporosis	4,047	22.7	23.6	signal
180	Therapeutic Product Effect Decreased	4,308	22.4	23.4	signal
181	Knee Arthroplasty	2,008	22.2	22.6	signal
182	Respiratory Symptom	269	22.1	22.2	signal
183	Diverticulum	687	22.0	22.1	signal
184	Walking Aid User	627	21.8	21.9	signal
185	Uterine Disorder	222	21.8	21.8	signal
186	Discomfort	5,728	21.7	23.0	signal
187	Lower Limb Fracture	1,804	21.7	22.1	signal
188	Aortic Arteriosclerosis	243	21.6	21.7	signal
189	Spinal Compression Fracture	785	21.5	21.6	signal
190	Joint Dislocation	965	21.0	21.2	signal
191	Rheumatoid Arthritis	10,282	20.8	23.1	signal
192	Tibia Fracture	428	20.8	20.9	signal
193	Osteitis	231	20.8	20.9	signal
194	Hepatic Enzyme Increased	6,133	20.7	21.9	signal
195	Osteosclerosis	141	20.4	20.5	signal
196	Radiculopathy	235	20.4	20.4	signal
197	Endodontic Procedure	224	20.1	20.2	signal
198	Abscess Oral	119	19.9	19.9	signal
199	Blood Pressure Systolic Abnormal	216	19.8	19.8	signal
200	Synovial Cyst	397	19.5	19.5	signal
201	Blood Pressure Diastolic Abnormal	219	19.4	19.4	signal
202	Swelling	7,884	19.2	20.8	signal
203	Lower Respiratory Tract Infection	3,791	19.0	19.7	signal
204	Breast Disorder	171	19.0	19.0	signal
205	Sensitivity Of Teeth	146	18.9	18.9	signal
206	Osteomyelitis	1,484	18.6	18.9	signal
207	Blister	4,529	18.3	19.1	signal
208	Back Injury	859	17.9	18.1	signal
209	Lupus-like Syndrome	711	17.8	17.9	signal
210	Spondylitis	286	17.8	17.9	signal
211	Foot Fracture	1,493	17.7	18.0	signal
212	Spinal Fusion Surgery	312	17.5	17.6	signal
213	Humerus Fracture	373	17.4	17.4	signal
214	Rotator Cuff Repair	133	17.3	17.3	signal
215	Patella Fracture	176	17.0	17.0	signal
216	Peptic Ulcer	250	16.9	17.0	signal
217	Hyperparathyroidism	155	16.9	17.0	signal
218	Tooth Fracture	824	16.8	17.0	signal
219	Oral Surgery	173	16.8	16.8	signal
220	Laryngitis	808	16.7	16.9	signal
221	Product Label Confusion	432	16.7	16.8	signal
222	Joint Effusion	512	16.6	16.7	signal
223	Cataract Operation	437	16.6	16.7	signal
224	Drug Tolerance	374	16.5	16.6	signal
225	Nasal Septum Deviation	144	16.5	16.6	signal
226	Joint Arthroplasty	132	16.5	16.6	signal
227	Prescribed Overdose	1,412	16.4	16.6	signal
228	Exposed Bone In Jaw	158	16.2	16.2	signal
229	Tooth Disorder	1,608	16.1	16.4	signal
230	Thoracic Vertebral Fracture	211	16.1	16.1	signal
231	Scleritis	114	16.0	16.0	signal
232	Stomatitis	4,255	15.7	16.4	signal
233	Drug Intolerance	6,713	15.6	16.7	signal
234	Actinic Keratosis	181	15.5	15.5	signal
235	Coeliac Disease	677	15.4	15.5	signal
236	Rhinitis Allergic	306	15.4	15.4	signal
237	Hypercalcaemia	843	15.3	15.4	signal
238	Compression Fracture	353	15.1	15.2	signal
239	Gingival Recession	129	15.0	15.0	signal
240	Polymyalgia Rheumatica	209	15.0	15.0	signal
241	Femoral Neck Fracture	343	14.9	15.0	signal
242	Basal Cell Carcinoma	1,030	14.7	14.8	signal
243	Normochromic Normocytic Anaemia	198	14.7	14.7	signal
244	Bone Lesion	238	14.7	14.7	signal
245	Alanine Aminotransferase Abnormal	138	14.7	14.7	signal
246	Excoriation	169	14.6	14.6	signal
247	Dyslipidaemia	331	14.5	14.5	signal
248	Eye Injury	196	14.5	14.5	signal
249	C-reactive Protein Increased	2,366	14.5	14.8	signal
250	Gait Inability	2,132	14.3	14.6	signal
251	Chronic Sinusitis	241	14.3	14.3	signal
252	Ulcer Haemorrhage	434	14.3	14.3	signal
253	Maternal Exposure During Pregnancy	5,652	14.3	15.0	signal
254	Breast Cancer Stage Ii	537	14.2	14.3	signal
255	Mastectomy	111	14.1	14.1	signal
256	Hypertonic Bladder	183	14.1	14.2	signal
257	Pustular Psoriasis	217	14.0	14.0	signal
258	Cardiac Murmur	547	14.0	14.0	signal
259	Hysterectomy	538	13.8	13.9	signal
260	Oesophageal Spasm	113	13.6	13.6	signal
261	Cervical Spinal Stenosis	106	13.6	13.6	signal
262	Wrist Fracture	732	13.5	13.6	signal
263	Atrophy	119	13.5	13.5	signal
264	Lobar Pneumonia	114	13.5	13.5	signal
265	Abdominal Discomfort	10,069	13.3	14.7	signal
266	Joint Swelling	7,205	13.2	14.2	signal
267	Red Blood Cell Sedimentation Rate Abnormal	139	13.2	13.2	signal
268	Rotator Cuff Syndrome	765	13.1	13.2	signal
269	Pelvic Fracture	459	13.1	13.1	signal
270	Carotid Artery Stenosis	207	13.0	13.1	signal
271	Thyroid Neoplasm	163	12.9	12.9	signal
272	Tooth Extraction	725	12.9	13.0	signal
273	Hiatus Hernia	755	12.9	13.0	signal
274	Muscle Strain	502	12.8	12.9	signal
275	Prescribed Underdose	1,150	12.7	12.9	signal
276	Rib Fracture	1,172	12.6	12.7	signal
277	Lumbar Vertebral Fracture	258	12.5	12.6	signal
278	Arteriosclerosis Coronary Artery	375	12.5	12.6	signal
279	Oral Disorder	417	12.5	12.6	signal
280	Night Sweats	1,825	12.5	12.7	signal
281	Inflammation	2,889	12.4	12.8	signal
282	Varicose Vein	290	12.3	12.3	signal
283	Wheezing	3,295	12.3	12.7	signal
284	Congenital Anomaly	426	12.0	12.1	signal
285	Tooth Abscess	554	11.9	12.0	signal
286	Gingivitis	292	11.9	11.9	signal
287	Diverticulum Intestinal	235	11.9	11.9	signal
288	Peripheral Vascular Disorder	279	11.8	11.9	signal
289	Polyarthritis	281	11.8	11.8	signal
290	Mobility Decreased	3,784	11.6	12.0	signal
291	Ill-defined Disorder	3,200	11.6	11.9	signal
292	Forced Expiratory Volume Decreased	149	11.5	11.6	signal
293	Gastrooesophageal Reflux Disease	4,159	11.4	11.8	signal
294	Alopecia	10,151	11.3	12.5	signal
295	Obstructive Airways Disorder	575	11.3	11.4	signal
296	Injury	3,619	11.2	11.6	signal
297	Road Traffic Accident	2,128	11.1	11.4	signal
298	Treatment Failure	4,157	11.1	11.5	signal
299	Periarthritis	114	11.1	11.1	signal
300	Musculoskeletal Pain	2,671	11.1	11.4	signal
301	Intervertebral Disc Disorder	217	11.1	11.1	signal
302	Diastolic Dysfunction	156	11.0	11.0	signal
303	Labyrinthitis	128	11.0	11.0	signal
304	Plantar Fasciitis	168	10.9	11.0	signal
305	Musculoskeletal Stiffness	4,350	10.9	11.3	signal
306	Goitre	202	10.8	10.8	signal
307	Atelectasis	475	10.7	10.8	signal
308	Lung Disorder	2,329	10.4	10.6	signal
309	Hand Fracture	337	10.4	10.4	signal
310	Cushingoid	153	10.3	10.4	signal
311	Ulcer	753	10.3	10.4	signal
312	Granuloma	162	10.2	10.2	signal
313	Oesophageal Ulcer	180	10.2	10.2	signal
314	Oedema	2,515	10.1	10.4	signal
315	Arteriosclerosis	438	10.1	10.2	signal
316	Foot Operation	227	10.1	10.1	signal
317	Rash Vesicular	222	10.1	10.1	signal
318	Ligament Sprain	451	10.0	10.0	signal
319	Oesophageal Stenosis	130	9.9	9.9	signal
320	Aphthous Stomatitis	106	9.9	9.9	signal
321	Left Ventricular Hypertrophy	192	9.8	9.8	signal
322	Bronchitis Chronic	110	9.7	9.8	signal
323	Fracture	844	9.7	9.8	signal
324	Gastrointestinal Disorder	3,924	9.7	10.0	signal
325	Hepatic Cirrhosis	828	9.6	9.7	signal
326	Device Failure	667	9.6	9.6	signal
327	Contusion	4,217	9.5	9.9	signal
328	Meniscus Injury	270	9.5	9.6	signal
329	Anxiety Disorder	147	9.5	9.5	signal
330	Ankle Fracture	677	9.5	9.6	signal
331	Renal Cyst	347	9.5	9.5	signal
332	Liver Function Test Increased	925	9.4	9.5	signal
333	Oesophageal Disorder	165	9.3	9.3	signal
334	Bronchiectasis	284	9.3	9.3	signal
335	Ear Pain	829	9.3	9.3	signal
336	Angiopathy	240	9.2	9.3	signal
337	Hepatic Cyst	144	9.2	9.2	signal
338	Lung Neoplasm	181	9.1	9.2	signal
339	Tendonitis	654	9.1	9.2	signal
340	Taste Disorder	842	9.1	9.2	signal
341	Sinusitis	4,316	9.1	9.5	signal
342	Sleep Disorder	2,921	9.1	9.3	signal
343	Renal Failure Chronic	325	9.1	9.1	signal
344	Hip Fracture	1,332	9.0	9.1	signal
345	Mastication Disorder	126	9.0	9.0	signal
346	Large Intestine Polyp	285	8.9	8.9	signal
347	General Physical Health Deterioration	4,708	8.9	9.3	signal
348	Trigger Finger	165	8.8	8.8	signal
349	Body Height Decreased	439	8.8	8.8	signal
350	Hypothyroidism	1,277	8.7	8.8	signal
351	Aortic Stenosis	139	8.6	8.7	signal
352	Clavicle Fracture	153	8.6	8.7	signal
353	Aortic Valve Incompetence	170	8.6	8.6	signal
354	Nodule	517	8.6	8.6	signal
355	Cholecystectomy	450	8.6	8.6	signal
356	Antinuclear Antibody Positive	129	8.6	8.6	signal
357	Carpal Tunnel Syndrome	555	8.6	8.6	signal
358	Nasal Polyps	189	8.5	8.5	signal
359	Normal Newborn	210	8.4	8.4	signal
360	Pulmonary Alveolar Haemorrhage	216	8.3	8.4	signal
361	Oesophagitis	420	8.3	8.3	signal
362	Crepitations	115	8.3	8.3	signal
363	Spinal Fracture	760	8.2	8.3	signal
364	Mitral Valve Incompetence	428	8.2	8.2	signal
365	Arthritis	2,979	8.2	8.4	signal
366	Intentional Product Use Issue	3,320	8.2	8.4	signal
367	Vitamin B12 Deficiency	151	8.1	8.1	signal
368	Myositis	337	8.1	8.1	signal
369	Groin Pain	331	8.1	8.1	signal
370	Spinal Disorder	356	8.1	8.1	signal
371	Liver Disorder	1,659	8.1	8.2	signal
372	Haemorrhoids	731	8.1	8.1	signal
373	Drug Eruption	657	8.1	8.1	signal
374	Skin Ulcer	955	8.0	8.1	signal
375	Joint Stiffness	970	8.0	8.1	signal
376	Hypertension	7,836	8.0	8.6	signal
377	Iron Deficiency Anaemia	339	8.0	8.0	signal
378	Neurological Symptom	209	8.0	8.0	signal
379	Intervertebral Disc Protrusion	806	7.9	8.0	signal
380	Delirium	1,270	7.9	8.0	signal
381	Hypersensitivity	6,789	7.9	8.4	signal
382	Loss Of Employment	111	7.9	7.9	signal
383	Otitis Media	119	7.8	7.8	signal
384	Loss Of Personal Independence In Daily Activities	1,700	7.7	7.8	signal
385	Laceration	340	7.7	7.7	signal
386	Blood Pressure Systolic Increased	698	7.7	7.7	signal
387	Bone Density Decreased	1,126	7.7	7.7	signal
388	Breath Sounds Abnormal	175	7.7	7.7	signal
389	Oedema Mouth	117	7.6	7.7	signal
390	Emphysema	356	7.6	7.6	signal
391	Urinary Tract Disorder	158	7.6	7.6	signal
392	Epilepsy	1,068	7.5	7.6	signal
393	Tongue Disorder	253	7.5	7.5	signal
394	Oesophageal Pain	136	7.4	7.4	signal
395	Dry Mouth	2,787	7.4	7.6	signal
396	Wound Complication	117	7.3	7.3	signal
397	Ecchymosis	233	7.3	7.3	signal
398	Bundle Branch Block Left	144	7.3	7.3	signal
399	Pregnancy	681	7.2	7.3	signal
400	Incorrect Route Of Product Administration	564	7.2	7.3	signal
401	Adverse Reaction	445	7.2	7.2	signal
402	Peripheral Swelling	5,140	7.2	7.5	signal
403	Infection	4,813	7.2	7.5	signal
404	Sleep Disorder Due To A General Medical Condition	537	7.1	7.2	signal
405	Exposure During Pregnancy	2,063	7.1	7.3	signal
406	Full Blood Count Abnormal	348	7.1	7.1	signal
407	Candidiasis	134	7.1	7.1	signal
408	Sleep Apnoea Syndrome	629	7.1	7.1	signal
409	Back Disorder	530	7.0	7.0	signal
410	Wound Dehiscence	110	7.0	7.0	signal
411	Deafness Neurosensory	106	7.0	7.0	signal
412	Pain In Jaw	915	6.9	7.0	signal
413	Adverse Event	2,973	6.9	7.1	signal
414	Wound Secretion	125	6.8	6.8	signal
415	Increased Tendency To Bruise	291	6.8	6.8	signal
416	Dyspepsia	3,035	6.6	6.8	signal
417	Melanocytic Naevus	135	6.6	6.6	signal
418	Breast Mass	207	6.6	6.6	signal
419	Therapy Non-responder	1,369	6.6	6.7	signal
420	Joint Injury	653	6.6	6.6	signal
421	Upper-airway Cough Syndrome	249	6.5	6.5	signal
422	Tooth Infection	399	6.5	6.5	signal
423	Confusional State	4,891	6.5	6.8	signal
424	Trismus	156	6.5	6.5	signal
425	Drug-induced Liver Injury	924	6.4	6.5	signal
426	Tricuspid Valve Incompetence	236	6.4	6.4	signal
427	Ear Infection	792	6.4	6.4	signal
428	Abdominal Hernia	135	6.3	6.3	signal
429	Facial Bones Fracture	108	6.3	6.3	signal
430	Neck Pain	1,640	6.3	6.4	signal
431	Gingival Pain	233	6.3	6.3	signal
432	Gastritis	768	6.3	6.3	signal
433	Bone Loss	438	6.2	6.2	signal
434	Upper Limb Fracture	575	6.2	6.2	signal
435	Bruxism	155	6.2	6.2	signal
436	Tendon Disorder	187	6.1	6.1	signal
437	Pulmonary Mass	422	6.1	6.1	signal
438	Hyperkeratosis	157	6.1	6.1	signal
439	Hypoaesthesia	4,220	6.0	6.3	signal
440	Asthma	3,149	6.0	6.2	signal
441	Cerebral Atrophy	112	6.0	6.0	signal
442	Product Use Issue	5,225	6.0	6.3	signal
443	Disability	553	6.0	6.0	signal
444	Glucose Tolerance Impaired	164	6.0	6.0	signal
445	General Symptom	210	6.0	6.0	signal
446	Tooth Loss	579	5.9	6.0	signal
447	Cardiomegaly	340	5.9	5.9	signal
448	Abscess	436	5.8	5.9	signal
449	Arthralgia	11,308	5.8	6.5	signal
450	Vasculitis	318	5.8	5.8	signal
451	Escherichia Urinary Tract Infection	114	5.7	5.7	signal
452	Rhinitis	215	5.7	5.7	signal
453	Nasopharyngitis	4,925	5.7	5.9	signal
454	Toothache	477	5.6	5.7	signal
455	Gingival Swelling	116	5.6	5.6	signal
456	Cataract	1,555	5.6	5.7	signal
457	Hepatitis	671	5.6	5.6	signal
458	Purulent Discharge	112	5.6	5.6	signal
459	Multiple Fractures	434	5.6	5.6	signal
460	Gingival Bleeding	358	5.6	5.6	signal
461	Diabetic Neuropathy	130	5.6	5.6	signal
462	Nocturia	315	5.6	5.6	signal
463	Drug Hypersensitivity	5,046	5.6	5.8	signal
464	Sinus Disorder	513	5.5	5.5	signal
465	Flank Pain	242	5.5	5.5	signal
466	Musculoskeletal Chest Pain	394	5.4	5.4	signal
467	Chronic Obstructive Pulmonary Disease	1,322	5.4	5.5	signal
468	Migraine	2,405	5.4	5.5	signal
469	Limb Operation	119	5.3	5.3	signal
470	Fall	8,280	5.3	5.7	signal
471	Bladder Disorder	247	5.3	5.3	signal
472	Coronary Artery Disease	757	5.3	5.3	signal
473	Uterine Leiomyoma	182	5.3	5.3	signal
474	Bronchitis	1,844	5.3	5.4	signal
475	Cyst	307	5.3	5.3	signal
476	Bundle Branch Block Right	114	5.3	5.3	signal
477	Muscular Weakness	2,794	5.2	5.4	signal
478	Fistula	276	5.2	5.2	signal
479	Body Temperature Decreased	243	5.2	5.2	signal
480	Rosacea	112	5.2	5.2	signal
481	Blood Pressure Diastolic Decreased	178	5.1	5.1	signal
482	Multiple Injuries	153	5.1	5.1	signal
483	Skin Abrasion	112	5.1	5.1	signal
484	Tenderness	250	5.1	5.1	signal
485	Oedema Peripheral	2,919	5.1	5.2	signal
486	Lung Infiltration	212	5.1	5.1	signal
487	Upper Respiratory Tract Infection	1,098	5.1	5.1	signal
488	Myopathy	206	5.1	5.1	signal
489	Nephrogenic Anaemia	111	5.1	5.1	signal
490	Wheelchair User	106	5.1	5.1	signal
491	Lymphoedema	163	5.0	5.0	signal
492	Weight Increased	5,161	4.9	5.1	signal
493	Amnesia	1,498	4.9	4.9	signal
494	Hypovolaemia	134	4.9	4.9	signal
495	Macular Degeneration	273	4.9	4.9	signal
496	Rales	132	4.8	4.8	signal
497	Vaginal Infection	107	4.8	4.8	signal
498	Limb Injury	614	4.8	4.8	signal
499	Hepatic Steatosis	421	4.8	4.8	signal
500	Benign Prostatic Hyperplasia	117	4.8	4.8	signal
501	Pain	13,848	4.8	5.4	signal
502	Pain In Extremity	6,619	4.8	5.0	signal
503	Adrenal Insufficiency	267	4.7	4.8	signal
504	Polyp	146	4.7	4.7	signal
505	Eosinophil Count Increased	183	4.7	4.7	signal
506	Cellulitis	1,107	4.7	4.7	signal
507	Adverse Drug Reaction	1,962	4.7	4.7	signal
508	Depression	4,976	4.6	4.8	signal
509	Glaucoma	418	4.6	4.6	signal
510	Therapeutic Product Effect Incomplete	1,533	4.6	4.7	signal
511	Seasonal Allergy	301	4.5	4.5	signal
512	Skin Laceration	229	4.5	4.5	signal
513	Restless Legs Syndrome	384	4.5	4.5	signal
514	Rash	9,099	4.5	4.8	signal
515	Chest Pain	3,865	4.4	4.6	signal
516	Gastric Ulcer	396	4.4	4.4	signal
517	Blood Pressure Fluctuation	500	4.4	4.4	signal
518	Urticaria	3,432	4.4	4.5	signal
519	Major Depression	151	4.4	4.4	signal
520	Hypokalaemia	945	4.4	4.4	signal
521	Respiratory Disorder	617	4.4	4.4	signal
522	Blood Calcium Decreased	232	4.4	4.4	signal
523	Multiple Allergies	161	4.4	4.4	signal
524	Condition Aggravated	6,131	4.3	4.5	signal
525	Pneumonia Aspiration	505	4.3	4.3	signal
526	Leukocytosis	365	4.3	4.3	signal
527	Oral Pain	451	4.3	4.3	signal
528	Blood Calcium Increased	176	4.3	4.3	signal
529	Haemorrhagic Stroke	156	4.2	4.2	signal
530	Musculoskeletal Discomfort	341	4.2	4.2	signal
531	Transfusion	208	4.2	4.2	signal
532	Squamous Cell Carcinoma	185	4.2	4.2	signal
533	Musculoskeletal Disorder	374	4.1	4.2	signal
534	Deformity	182	4.1	4.1	signal
535	Weight Fluctuation	202	4.1	4.1	signal
536	Bone Pain	1,133	4.1	4.1	signal
537	Peroneal Nerve Palsy	109	4.1	4.1	signal
538	Malnutrition	211	4.0	4.0	signal
539	Sputum Discoloured	177	4.0	4.0	signal
540	Urinary Incontinence	554	4.0	4.0	signal
541	Vitamin D Decreased	160	4.0	4.0	signal
542	Abdominal Pain Upper	3,814	3.9	4.1	signal
543	Rash Pruritic	995	3.9	3.9	signal
544	Decubitus Ulcer	150	3.9	3.9	signal
545	Gait Disturbance	3,529	3.9	4.0	signal
546	Aortic Aneurysm	140	3.9	3.9	signal
547	Respiratory Rate Increased	162	3.9	3.9	signal
548	Rectal Haemorrhage	780	3.8	3.9	signal
549	Oral Candidiasis	234	3.8	3.8	signal
550	Cardiac Pacemaker Insertion	107	3.8	3.8	signal
551	Gallbladder Disorder	320	3.8	3.8	signal
552	Muscle Spasms	3,254	3.8	3.8	signal
553	Anxiety	5,034	3.7	3.9	signal
554	Aspartate Aminotransferase Increased	936	3.7	3.8	signal
555	Mass	247	3.7	3.7	signal
556	Micturition Urgency	199	3.7	3.7	signal
557	Electrocardiogram Abnormal	138	3.7	3.7	signal
558	Memory Impairment	2,383	3.7	3.7	signal
559	Thyroid Disorder	267	3.7	3.7	signal
560	Frequent Bowel Movements	464	3.7	3.7	signal
561	Medical Device Complication	129	3.6	3.6	signal
562	Cystitis	548	3.6	3.6	signal
563	Productive Cough	811	3.6	3.6	signal
564	Fatigue	13,187	3.6	4.0	signal
565	Immunodeficiency	250	3.6	3.6	signal
566	Insomnia	4,526	3.6	3.7	signal
567	Medication Error	941	3.6	3.6	signal
568	Blood Iron Decreased	199	3.6	3.6	signal
569	Incorrect Product Administration Duration	342	3.6	3.6	signal
570	Back Pain	3,917	3.6	3.7	signal
571	Diverticulitis	462	3.5	3.5	signal
572	Nerve Compression	154	3.5	3.5	signal
573	Respiratory Tract Infection	434	3.5	3.5	signal
574	Pneumonia	5,320	3.5	3.6	signal
575	Paraesthesia	2,589	3.5	3.5	signal
576	Body Temperature Increased	336	3.5	3.5	signal
577	Haematuria	560	3.5	3.5	signal
578	Haematemesis	415	3.5	3.5	signal
579	Atrioventricular Block Complete	109	3.5	3.5	signal
580	Herpes Zoster	934	3.4	3.5	signal
581	Transient Ischaemic Attack	547	3.4	3.4	signal
582	Decreased Appetite	3,733	3.4	3.5	signal
583	Nephrolithiasis	736	3.4	3.4	signal
584	Post Procedural Infection	130	3.4	3.4	signal
585	Ocular Discomfort	174	3.4	3.4	signal
586	Skeletal Injury	167	3.4	3.4	signal
587	Clostridium Difficile Colitis	169	3.4	3.4	signal
588	Facial Pain	141	3.3	3.3	signal
589	Gastroenteritis	230	3.3	3.3	signal
590	Urinary Tract Infection	2,647	3.3	3.4	signal
591	Alanine Aminotransferase Increased	952	3.3	3.3	signal
592	Haematocrit Decreased	308	3.3	3.3	signal
593	Dermatitis Contact	175	3.3	3.3	signal
594	Haematoma	400	3.2	3.3	signal
595	Hypoaesthesia Oral	230	3.2	3.2	signal
596	Supraventricular Tachycardia	146	3.2	3.2	signal
597	Knee Operation	148	3.2	3.2	signal
598	White Blood Cell Count Increased	586	3.2	3.2	signal
599	Pyelonephritis	131	3.2	3.2	signal
600	Photophobia	283	3.2	3.2	signal
601	Gout	272	3.2	3.2	signal
602	Ventricular Extrasystoles	157	3.2	3.2	signal
603	Heart Rate Irregular	342	3.2	3.2	signal
604	Pyrexia	5,206	3.2	3.3	signal
605	Mouth Ulceration	316	3.2	3.2	signal
606	Pharyngitis	187	3.2	3.2	signal
607	Dyspnoea Exertional	563	3.2	3.2	signal
608	Pulmonary Hypertension	312	3.2	3.2	signal
609	Myocardial Ischaemia	171	3.1	3.2	signal
610	Gastric Disorder	516	3.1	3.1	signal
611	Cholelithiasis	486	3.1	3.1	signal
612	Blood Albumin Decreased	117	3.1	3.1	signal
613	Muscle Spasticity	182	3.1	3.1	signal
614	Hypoxia	513	3.1	3.1	signal
615	Skin Lesion	398	3.1	3.1	signal
616	Hydronephrosis	109	3.1	3.1	signal
617	Upper Gastrointestinal Haemorrhage	246	3.1	3.1	signal
618	Incontinence	152	3.0	3.0	signal
619	Haemoptysis	401	3.0	3.0	signal
620	Gastroenteritis Viral	258	3.0	3.0	signal
621	Blood Disorder	114	3.0	3.0	signal
622	Skin Cancer	305	3.0	3.0	signal
623	Deafness	370	3.0	3.0	signal
624	Head Injury	444	3.0	3.0	signal
625	Limb Discomfort	432	2.9	3.0	signal
626	Pollakiuria	581	2.9	3.0	signal
627	Ovarian Cyst	140	2.9	2.9	signal
628	Abdominal Pain	3,206	2.9	3.0	signal
629	Dyspnoea	7,764	2.9	3.1	signal
630	Hypocalcaemia	259	2.9	2.9	signal
631	Sinus Bradycardia	132	2.9	2.9	signal
632	Asthenia	5,053	2.8	2.9	signal
633	Sinus Congestion	181	2.8	2.8	signal
634	Pruritus	5,049	2.8	2.9	signal
635	Therapeutic Response Decreased	805	2.8	2.8	signal
636	Sinus Tachycardia	189	2.8	2.8	signal
637	Anorexia	174	2.8	2.8	signal
638	Urosepsis	121	2.8	2.8	signal
639	Atrial Fibrillation	1,270	2.7	2.8	signal
640	Pseudomonas Infection	110	2.7	2.7	signal
641	Deep Vein Thrombosis	842	2.7	2.7	signal
642	Liver Function Test Abnormal	377	2.7	2.7	signal
643	Cardiac Failure Congestive	1,041	2.7	2.7	signal
644	Generalised Oedema	158	2.7	2.7	signal
645	Abdominal Distension	1,326	2.7	2.7	signal
646	Fungal Infection	423	2.7	2.7	signal
647	Conjunctivitis	233	2.7	2.7	signal
648	Hypokinesia	183	2.7	2.7	signal
649	Dysuria	464	2.7	2.7	signal
650	Nerve Injury	140	2.6	2.6	signal
651	Oxygen Saturation Decreased	694	2.6	2.6	signal
652	Renal Failure Acute	534	2.6	2.6	signal
653	Blood Urine Present	236	2.6	2.6	signal
654	Neuralgia	300	2.6	2.6	signal
655	Myalgia	2,102	2.6	2.6	signal
656	Quality Of Life Decreased	166	2.6	2.6	signal
657	Heart Rate Decreased	436	2.6	2.6	signal
658	Post Procedural Haemorrhage	144	2.6	2.6	signal
659	Spinal Pain	144	2.6	2.6	signal
660	Tendon Rupture	152	2.6	2.6	signal
661	Tinnitus	565	2.6	2.6	signal
662	Dysphagia	1,160	2.6	2.6	signal
663	Fluid Retention	623	2.6	2.6	signal
664	Spinal Operation	148	2.6	2.6	signal
665	Anaemia	2,322	2.6	2.6	signal
666	Surgery	705	2.6	2.6	signal
667	Dizziness	6,053	2.6	2.7	signal
668	Hyponatraemia	683	2.6	2.6	signal
669	Respiratory Tract Congestion	193	2.6	2.6	signal
670	Weight Decreased	3,378	2.5	2.6	signal
671	Dermatitis	249	2.5	2.5	signal
672	Balance Disorder	1,039	2.5	2.5	signal
673	Presyncope	289	2.5	2.5	signal
674	Coma	569	2.5	2.5	signal
675	Product Use In Unapproved Indication	2,912	2.5	2.6	signal
676	Injection Site Reaction	816	2.5	2.5	signal
677	Gastrointestinal Pain	130	2.5	2.5	signal
678	Staphylococcal Infection	392	2.5	2.5	signal
679	Movement Disorder	380	2.5	2.5	signal
680	Vomiting	5,497	2.5	2.6	signal
681	Blood Urea Increased	196	2.5	2.5	signal
682	Platelet Count Increased	152	2.4	2.5	signal
683	Malaise	5,098	2.4	2.5	signal
684	Small Intestinal Obstruction	141	2.4	2.4	signal
685	Constipation	2,483	2.4	2.5	signal
686	Headache	7,181	2.4	2.5	signal
687	Head Discomfort	202	2.4	2.4	signal
688	Localised Infection	277	2.4	2.4	signal
689	Aspiration	124	2.4	2.4	signal
690	Retinal Detachment	105	2.4	2.4	signal
691	Acute Respiratory Failure	218	2.4	2.4	signal
692	Dementia	317	2.4	2.4	signal
693	Blood Potassium Decreased	341	2.4	2.4	signal
694	Muscle Atrophy	142	2.4	2.4	signal
695	Hyperthyroidism	163	2.4	2.4	signal
696	Pleural Effusion	680	2.3	2.4	signal
697	Interstitial Lung Disease	537	2.3	2.3	signal
698	Tachycardia	984	2.3	2.3	signal
699	Blood Pressure Increased	1,695	2.3	2.3	signal
700	Oral Herpes	215	2.3	2.3	signal
701	Blood Alkaline Phosphatase Increased	273	2.3	2.3	signal
702	Diplopia	285	2.3	2.3	signal
703	Diarrhoea	7,025	2.3	2.4	signal
704	Colitis Ulcerative	487	2.3	2.3	signal
705	Local Swelling	193	2.3	2.3	signal
706	Cough	3,049	2.3	2.3	signal
707	Breast Pain	116	2.3	2.3	signal
708	Nephropathy	102	2.3	2.3	signal
709	Haemoglobin Decreased	1,118	2.3	2.3	signal
710	Syncope	1,084	2.3	2.3	signal
711	Viral Infection	359	2.3	2.3	signal
712	Cholecystitis	128	2.3	2.3	signal
713	Bacterial Infection	200	2.3	2.3	signal
714	Laboratory Test Abnormal	315	2.2	2.3	signal
715	Vertigo	651	2.2	2.3	signal
716	Skin Infection	119	2.2	2.2	signal
717	Eye Pain	588	2.2	2.2	signal
718	Visual Impairment	1,307	2.2	2.3	signal
719	Device Related Infection	163	2.2	2.2	signal
720	Oral Discomfort	145	2.2	2.2	signal
721	Economic Problem	160	2.2	2.2	signal
722	Poor Venous Access	107	2.2	2.2	signal
723	Anhedonia	273	2.2	2.2	signal
724	Underdose	753	2.2	2.2	signal
725	Dysphonia	600	2.2	2.2	signal
726	Malignant Melanoma	137	2.1	2.1	signal
727	Eye Infection	114	2.1	2.1	signal
728	Hypomagnesaemia	141	2.1	2.1	signal
729	Activities Of Daily Living Impaired	204	2.1	2.1	signal
730	Secretion Discharge	125	2.1	2.1	signal
731	International Normalised Ratio Increased	291	2.1	2.1	signal
732	Blood Sodium Decreased	190	2.1	2.1	signal
733	Eating Disorder	215	2.1	2.1	signal
734	Angina Pectoris	290	2.1	2.1	signal
735	Nausea	7,844	2.1	2.2	signal
736	Hernia	191	2.1	2.1	signal
737	Abasia	248	2.1	2.1	signal
738	Mental Status Changes	275	2.1	2.1	signal
739	Vitreous Floaters	96	2.1	2.1	signal
740	Pancreatitis	521	2.1	2.1	signal
741	Heart Rate Increased	970	2.1	2.1	signal
742	Post Procedural Complication	188	2.1	2.1	signal
743	Skin Disorder	325	2.1	2.1	signal
744	Lymphadenopathy	346	2.1	2.1	signal
745	Hypoacusis	417	2.0	2.0	signal
746	Coordination Abnormal	136	2.0	2.0	signal
747	Cardiomyopathy	143	2.0	2.0	signal
748	Oropharyngeal Pain	893	2.0	2.0	signal
749	Drug Ineffective	12,683	2.0	2.2	signal
750	Gastrointestinal Haemorrhage	802	2.0	2.0	signal
751	Poor Quality Sleep	204	2.0	2.0	signal
752	Orthostatic Hypotension	166	2.0	2.0	no signal
753	Coagulopathy	158	2.0	2.0	no signal
754	Diabetes Mellitus	727	2.0	2.0	no signal
755	Scar	162	2.0	2.0	no signal
756	Dry Eye	452	2.0	2.0	no signal
757	Scratch	96	1.9	1.9	no signal
758	Feeling Hot	565	1.9	1.9	no signal
759	Neuropathy Peripheral	863	1.9	1.9	no signal
760	Nasal Congestion	534	1.9	1.9	no signal
761	Eye Disorder	299	1.9	1.9	no signal
762	Metastases To Bone	149	1.9	1.9	no signal
763	Dysstasia	266	1.9	1.9	no signal
764	Pharmaceutical Product Complaint	238	1.9	1.9	no signal
765	Off Label Use	7,803	1.9	2.0	no signal
766	Pulmonary Congestion	118	1.9	1.9	no signal
767	Lung Infection	140	1.9	1.9	no signal
768	Ileus	108	1.8	1.8	no signal
769	Lymphoma	136	1.8	1.8	no signal
770	Altered State Of Consciousness	188	1.8	1.8	no signal
771	Blood Count Abnormal	134	1.8	1.8	no signal
772	Ear Discomfort	89	1.8	1.8	no signal
773	Eyelid Ptosis	88	1.8	1.8	no signal
774	Dehydration	1,154	1.8	1.8	no signal
775	Electrolyte Imbalance	99	1.8	1.8	no signal
776	Rhinorrhoea	553	1.8	1.8	no signal
777	Dry Throat	87	1.8	1.8	no signal
778	Chronic Kidney Disease	651	1.8	1.8	no signal
779	Decreased Activity	91	1.8	1.8	no signal
780	Chills	993	1.8	1.8	no signal
781	Pneumothorax	134	1.8	1.8	no signal
782	Blood Potassium Increased	137	1.8	1.8	no signal
783	Melaena	186	1.8	1.8	no signal
784	Hyperglycaemia	305	1.8	1.8	no signal
785	Thrombosis	676	1.8	1.8	no signal
786	Blood Triglycerides Increased	148	1.8	1.8	no signal
787	Middle Insomnia	155	1.7	1.7	no signal
788	Stress	599	1.7	1.8	no signal
789	Bipolar Disorder	91	1.7	1.7	no signal
790	Emotional Distress	1,006	1.7	1.7	no signal
791	Urinary Retention	274	1.7	1.7	no signal
792	Influenza	920	1.7	1.7	no signal
793	Red Blood Cell Count Decreased	235	1.7	1.7	no signal
794	Blood Test Abnormal	115	1.7	1.7	no signal
795	Pulmonary Embolism	780	1.7	1.7	no signal
796	Panic Attack	298	1.7	1.7	no signal
797	Sepsis	909	1.7	1.7	no signal
798	Feeling Cold	227	1.7	1.7	no signal
799	Pelvic Pain	148	1.7	1.7	no signal
800	Blindness	329	1.7	1.7	no signal
801	Hot Flush	608	1.7	1.7	no signal
802	Temperature Intolerance	82	1.7	1.7	no signal
803	Dermatitis Allergic	100	1.7	1.7	no signal
804	Choking	155	1.7	1.7	no signal
805	Appendicitis	74	1.7	1.7	no signal
806	Treatment Noncompliance	431	1.7	1.7	no signal
807	Septic Shock	342	1.7	1.7	no signal
808	Throat Irritation	353	1.7	1.7	no signal
809	Faeces Discoloured	171	1.7	1.7	no signal
810	Arrhythmia	374	1.6	1.7	no signal
811	Diabetes Mellitus Inadequate Control	139	1.6	1.6	no signal
812	Flatulence	443	1.6	1.6	no signal
813	Renal Failure	1,045	1.6	1.6	no signal
814	Ascites	229	1.6	1.6	no signal
815	Aphonia	108	1.6	1.6	no signal
816	Subarachnoid Haemorrhage	79	1.6	1.6	no signal
817	Ataxia	92	1.6	1.6	no signal
818	Palpitations	902	1.6	1.6	no signal
819	Petechiae	80	1.6	1.6	no signal
820	Lymphopenia	108	1.6	1.6	no signal
821	Blood Creatinine Increased	502	1.6	1.6	no signal
822	Convulsion	445	1.6	1.6	no signal
823	Paraesthesia Oral	110	1.6	1.6	no signal
824	Renal Disorder	357	1.6	1.6	no signal
825	Sensory Disturbance	123	1.6	1.6	no signal
826	Eructation	145	1.6	1.6	no signal
827	Respiratory Failure	556	1.6	1.6	no signal
828	Myelodysplastic Syndrome	110	1.6	1.6	no signal
829	Nervousness	398	1.6	1.6	no signal
830	Cardiac Disorder	707	1.6	1.6	no signal
831	Blindness Unilateral	106	1.6	1.6	no signal
832	Cardiac Failure	604	1.6	1.6	no signal
833	Product Quality Issue	1,007	1.6	1.6	no signal
834	Neoplasm	86	1.6	1.6	no signal
835	Breast Cancer Stage I	70	1.6	1.6	no signal
836	Fear	202	1.6	1.6	no signal
837	Feeling Jittery	142	1.6	1.6	no signal
838	Splenomegaly	87	1.6	1.6	no signal
839	Psoriasis	971	1.6	1.6	no signal
840	Muscle Tightness	120	1.6	1.6	no signal
841	Eye Haemorrhage	99	1.6	1.6	no signal
842	Coronary Artery Occlusion	102	1.6	1.6	no signal
843	Bronchospasm	105	1.5	1.5	no signal
844	Hypotension	1,467	1.5	1.5	no signal
845	Intestinal Obstruction	274	1.5	1.5	no signal
846	Procedural Pain	202	1.5	1.5	no signal
847	Dizziness Postural	70	1.5	1.5	no signal
848	Kidney Infection	142	1.5	1.5	no signal
849	Initial Insomnia	73	1.5	1.5	no signal
850	Colitis	269	1.5	1.5	no signal
851	Impaired Gastric Emptying	91	1.5	1.5	no signal
852	Hypophagia	180	1.5	1.5	no signal
853	Inappropriate Schedule Of Drug Administration	511	1.5	1.5	no signal
854	Acute Myocardial Infarction	209	1.5	1.5	no signal
855	Chest Discomfort	719	1.5	1.5	no signal
856	Swelling Face	458	1.5	1.5	no signal
857	Impaired Work Ability	151	1.5	1.5	no signal
858	Colon Cancer	105	1.5	1.5	no signal
859	Ventricular Tachycardia	116	1.5	1.5	no signal
860	Breast Cancer	656	1.5	1.5	no signal
861	Multi-organ Failure	122	1.5	1.5	no signal
862	Drug Administration Error	216	1.5	1.5	no signal
863	Loss Of Consciousness	888	1.5	1.5	no signal
864	Blood Pressure Decreased	459	1.4	1.5	no signal
865	Renal Tubular Necrosis	68	1.4	1.4	no signal
866	Influenza Like Illness	571	1.4	1.4	no signal
867	End Stage Renal Disease	127	1.4	1.4	no signal
868	Eye Inflammation	65	1.4	1.4	no signal
869	Epistaxis	515	1.4	1.4	no signal
870	Visual Acuity Reduced	230	1.4	1.4	no signal
871	Immune System Disorder	90	1.4	1.4	no signal
872	Dysarthria	257	1.4	1.4	no signal
873	Peripheral Coldness	94	1.4	1.4	no signal
874	Hyperkalaemia	238	1.4	1.4	no signal
875	Hair Texture Abnormal	92	1.4	1.4	no signal
876	Breast Cancer Metastatic	73	1.4	1.4	no signal
877	Burning Sensation	476	1.4	1.4	no signal
878	Erythema	1,393	1.4	1.4	no signal
879	Somnolence	1,364	1.4	1.4	no signal
880	Vision Blurred	924	1.4	1.4	no signal
881	Cerebrovascular Accident	1,148	1.4	1.4	no signal
882	Accident	80	1.4	1.4	no signal
883	Chromaturia	150	1.4	1.4	no signal
884	No Therapeutic Response	82	1.4	1.4	no signal
885	Abdominal Pain Lower	168	1.4	1.4	no signal
886	Diarrhoea Haemorrhagic	62	1.4	1.4	no signal
887	Hemiparesis	112	1.4	1.4	no signal
888	Jaundice	177	1.4	1.4	no signal
889	Breast Cancer Female	176	1.4	1.4	no signal
890	Speech Disorder	342	1.4	1.4	no signal
891	Uveitis	88	1.4	1.4	no signal
892	Blood Thyroid Stimulating Hormone Increased	60	1.4	1.4	no signal
893	Ovarian Cancer	60	1.4	1.4	no signal
894	Subdural Haematoma	93	1.4	1.4	no signal
895	Pulmonary Oedema	290	1.4	1.4	no signal
896	Tuberculosis	83	1.4	1.4	no signal
897	Lacrimation Increased	192	1.3	1.3	no signal
898	Inflammatory Bowel Disease	63	1.3	1.3	no signal
899	Device Breakage	251	1.3	1.3	no signal
900	Pericardial Effusion	147	1.3	1.3	no signal
901	Gastric Haemorrhage	74	1.3	1.3	no signal
902	Sneezing	142	1.3	1.3	no signal
903	Cerebral Infarction	155	1.3	1.3	no signal
904	Inappropriate Antidiuretic Hormone Secretion	64	1.3	1.3	no signal
905	Hypoglycaemia	304	1.3	1.3	no signal
906	Myocardial Infarction	1,098	1.3	1.3	no signal
907	Polyneuropathy	74	1.3	1.3	no signal
908	Hallucination	465	1.3	1.3	no signal
909	Bacteraemia	73	1.3	1.3	no signal
910	Leukopenia	309	1.3	1.3	no signal
911	Gamma-glutamyltransferase Increased	137	1.3	1.3	no signal
912	Swollen Tongue	193	1.3	1.3	no signal
913	Pancytopenia	344	1.3	1.3	no signal
914	Vaginal Discharge	62	1.3	1.3	no signal
915	Blood Pressure Abnormal	122	1.3	1.3	no signal
916	Ankylosing Spondylitis	80	1.3	1.3	no signal
917	Erythema Multiforme	57	1.3	1.3	no signal
918	Candida Infection	101	1.3	1.3	no signal
919	Neutrophil Count Increased	62	1.3	1.3	no signal
920	Respiratory Distress	166	1.3	1.3	no signal
921	Haematochezia	331	1.3	1.3	no signal
922	Pneumonitis	162	1.3	1.3	no signal
923	Bradycardia	317	1.2	1.2	no signal
924	Fluid Overload	87	1.2	1.2	no signal
925	Proteinuria	111	1.2	1.2	no signal
926	Ageusia	147	1.2	1.2	no signal
927	Thinking Abnormal	110	1.2	1.2	no signal
928	Renal Pain	62	1.2	1.2	no signal
929	Cardio-respiratory Arrest	247	1.2	1.2	no signal
930	Muscle Twitching	135	1.2	1.2	no signal
931	Thrombocytopenia	646	1.2	1.2	no signal
932	Photosensitivity Reaction	95	1.2	1.2	no signal
933	Cardiovascular Disorder	147	1.2	1.2	no signal
934	Clostridium Difficile Infection	124	1.2	1.2	no signal
935	Blood Creatine Phosphokinase Increased	167	1.2	1.2	no signal
936	Disorientation	224	1.2	1.2	no signal
937	Injection Site Irritation	71	1.2	1.2	no signal
938	Pruritus Generalised	122	1.2	1.2	no signal
939	Scab	63	1.2	1.2	no signal
940	Retching	118	1.2	1.2	no signal
941	Aphasia	168	1.2	1.2	no signal
942	Motor Dysfunction	56	1.2	1.2	no signal
943	Hepatotoxicity	122	1.2	1.2	no signal
944	Lethargy	316	1.1	1.1	no signal
945	Transaminases Increased	122	1.1	1.1	no signal
946	Eye Discharge	56	1.1	1.1	no signal
947	Throat Tightness	148	1.1	1.1	no signal
948	Ocular Hyperaemia	255	1.1	1.1	no signal
949	Blood Lactate Dehydrogenase Increased	87	1.1	1.1	no signal
950	Disseminated Intravascular Coagulation	77	1.1	1.1	no signal
951	Tubulointerstitial Nephritis	102	1.1	1.1	no signal
952	Pancreatitis Acute	121	1.1	1.1	no signal
953	Dysgeusia	403	1.1	1.1	no signal
954	Circulatory Collapse	92	1.1	1.1	no signal
955	Flushing	545	1.1	1.1	no signal
956	Haemorrhage	557	1.1	1.1	no signal
957	Eosinophilia	93	1.1	1.1	no signal
958	Neoplasm Malignant	354	1.1	1.1	no signal
959	Pulmonary Arterial Hypertension	77	1.1	1.1	no signal
960	Tremor	878	1.1	1.1	no signal
961	Thirst	94	1.1	1.1	no signal
962	Hepatomegaly	52	1.1	1.1	no signal
963	White Blood Cell Count Decreased	571	1.1	1.1	no signal
964	Metastases To Liver	92	1.1	1.1	no signal
965	Libido Decreased	65	1.1	1.1	no signal
966	Grand Mal Convulsion	49	1.1	1.1	no signal
967	Pulmonary Thrombosis	57	1.1	1.1	no signal
968	Blood Bilirubin Increased	141	1.1	1.1	no signal
969	Hypersomnia	149	1.1	1.1	no signal
970	Hepatic Function Abnormal	192	1.1	1.1	no signal
971	Bedridden	68	1.1	1.1	no signal
972	Pharyngitis Streptococcal	56	1.1	1.1	no signal
973	Infusion Site Pain	66	1.1	1.1	no signal
974	Lymphocyte Count Decreased	90	1.1	1.1	no signal
975	Eczema	255	1.1	1.1	no signal
976	Hospitalisation	771	1.1	1.1	no signal
977	Anosmia	73	1.1	1.1	no signal
978	Ejection Fraction Decreased	78	1.0	1.0	no signal
979	Full Blood Count Decreased	101	1.0	1.0	no signal
980	Hair Colour Changes	63	1.0	1.0	no signal
981	Feeling Abnormal	1,203	1.0	1.0	no signal
982	Foetal Exposure During Pregnancy	404	1.0	1.0	no signal
983	Lip Swelling	165	1.0	1.0	no signal
984	Lung Neoplasm Malignant	204	1.0	1.0	no signal
985	Renal Impairment	413	1.0	1.0	no signal
986	Sluggishness	50	1.0	1.0	no signal
987	Incorrect Drug Administration Duration	140	1.0	1.0	no signal
988	Intestinal Perforation	55	1.0	1.0	no signal
989	Cyanosis	77	1.0	1.0	no signal
990	Rash Maculo-papular	108	1.0	1.0	no signal
991	Sudden Death	52	1.0	1.0	no signal
992	Hallucination, Visual	102	1.0	1.0	no signal
993	Mental Disorder	211	1.0	1.0	no signal
994	Skin Reaction	68	1.0	1.0	no signal
995	Impaired Driving Ability	55	1.0	1.0	no signal
996	Eye Irritation	268	1.0	1.0	no signal
997	Glomerular Filtration Rate Decreased	58	1.0	1.0	no signal
998	Cold Sweat	84	1.0	1.0	no signal
999	Drug Interaction	753	1.0	1.0	no signal
1000	Disease Recurrence	226	1.0	1.0	no signal
1001	Hyperhidrosis	604	1.0	1.0	no signal
1002	Renal Injury	140	1.0	1.0	no signal
1003	Face Oedema	79	1.0	1.0	no signal
1004	Unresponsive To Stimuli	119	1.0	1.0	no signal
1005	Skin Discolouration	211	1.0	1.0	no signal
1006	Wrong Technique In Drug Usage Process	169	1.0	1.0	no signal
1007	Injection Site Haemorrhage	361	1.0	1.0	no signal
1008	Eye Swelling	168	0.9	0.9	no signal
1009	Complication Associated With Device	60	0.9	0.9	no signal
1010	Rash Generalised	119	0.9	0.9	no signal
1011	Dyskinesia	183	0.9	0.9	no signal
1012	Anaphylactic Reaction	247	0.9	0.9	no signal
1013	Acute Respiratory Distress Syndrome	79	0.9	0.9	no signal
1014	Madarosis	52	0.9	0.9	no signal
1015	Nervous System Disorder	139	0.9	0.9	no signal
1016	Blood Glucose Abnormal	82	0.9	0.9	no signal
1017	Platelet Count Decreased	471	0.9	0.9	no signal
1018	Injection Site Pruritus	294	0.9	0.9	no signal
1019	Mucosal Inflammation	115	0.9	0.9	no signal
1020	Parkinsonism	43	0.9	0.9	no signal
1021	Encephalopathy	108	0.9	0.9	no signal
1022	Overdose	953	0.9	0.9	no signal
1023	Multiple Sclerosis	210	0.9	0.9	no signal
1024	Pallor	119	0.9	0.9	no signal
1025	Cerebral Haemorrhage	155	0.9	0.9	no signal
1026	Agitation	319	0.9	0.9	no signal
1027	Therapy Cessation	221	0.9	0.9	no signal
1028	Paralysis	62	0.9	0.9	no signal
1029	Salivary Hypersecretion	43	0.9	0.9	no signal
1030	Injection Site Rash	130	0.9	0.9	no signal
1031	Agranulocytosis	79	0.9	0.9	no signal
1032	Pharyngeal Oedema	66	0.9	0.9	no signal
1033	Rhabdomyolysis	176	0.9	0.9	no signal
1034	Covid-19 Pneumonia	50	0.9	0.9	no signal
1035	Drug Level Decreased	43	0.9	0.9	no signal
1036	Injection Site Discolouration	52	0.9	0.9	no signal
1037	Rash Macular	146	0.9	0.9	no signal
1038	Rash Papular	94	0.9	0.9	no signal
1039	Cognitive Disorder	194	0.9	0.9	no signal
1040	Impaired Quality Of Life	60	0.9	0.9	no signal
1041	Abnormal Dreams	115	0.9	0.9	no signal
1042	Drug Effect Decreased	226	0.9	0.9	no signal
1043	Feeding Disorder	82	0.9	0.9	no signal
1044	Acute Kidney Injury	625	0.9	0.9	no signal
1045	Decreased Immune Responsiveness	40	0.9	0.9	no signal
1046	Shock	93	0.9	0.9	no signal
1047	Intraocular Pressure Increased	52	0.8	0.8	no signal
1048	Rash Erythematous	189	0.8	0.8	no signal
1049	Intentional Dose Omission	110	0.8	0.8	no signal
1050	Injection Site Erythema	496	0.8	0.8	no signal
1051	Product Administration Error	80	0.8	0.8	no signal
1052	Accidental Overdose	146	0.8	0.8	no signal
1053	Metastases To Lung	46	0.8	0.8	no signal
1054	Eye Pruritus	131	0.8	0.8	no signal
1055	Injection Site Haematoma	58	0.8	0.8	no signal
1056	Illness	397	0.8	0.8	no signal
1057	Emotional Disorder	122	0.8	0.8	no signal
1058	Injection Site Extravasation	49	0.8	0.8	no signal
1059	Brain Neoplasm	36	0.8	0.8	no signal
1060	Stevens-johnson Syndrome	87	0.8	0.8	no signal
1061	Unevaluable Event	295	0.8	0.8	no signal
1062	Bone Marrow Failure	79	0.8	0.8	no signal
1063	Ischaemic Stroke	69	0.8	0.8	no signal
1064	Myoclonus	46	0.8	0.8	no signal
1065	Hepatitis C	47	0.8	0.8	no signal
1066	Drug Dose Omission	645	0.8	0.8	no signal
1067	Drug Toxicity	53	0.8	0.8	no signal
1068	Product Dose Omission	254	0.8	0.8	no signal
1069	Injection Site Nodule	42	0.8	0.8	no signal
1070	Sars-cov-2 Test Positive	51	0.8	0.8	no signal
1071	Inappropriate Schedule Of Product Administration	674	0.8	0.8	no signal
1072	Increased Appetite	71	0.8	0.8	no signal
1073	Pharyngeal Swelling	36	0.8	0.8	no signal
1074	Hospice Care	37	0.8	0.8	no signal
1075	Delusion	58	0.8	0.8	no signal
1076	Product Use Complaint	58	0.8	0.8	no signal
1077	Mental Impairment	90	0.8	0.8	no signal
1078	Tachypnoea	50	0.8	0.8	no signal
1079	Skin Exfoliation	306	0.8	0.8	no signal
1080	Drug Level Increased	61	0.8	0.8	no signal
1081	Depressed Mood	193	0.8	0.8	no signal
1082	Therapy Partial Responder	55	0.8	0.8	no signal
1083	Central Nervous System Lesion	50	0.8	0.8	no signal
1084	Product Dose Omission In Error	97	0.8	0.8	no signal
1085	Prostatic Specific Antigen Increased	50	0.8	0.8	no signal
1086	Serotonin Syndrome	69	0.8	0.8	no signal
1087	Nephropathy Toxic	40	0.7	0.7	no signal
1088	Insurance Issue	53	0.7	0.7	no signal
1089	Thyroid Cancer	43	0.7	0.7	no signal
1090	Depressed Level Of Consciousness	140	0.7	0.7	no signal
1091	Toxic Epidermal Necrolysis	53	0.7	0.7	no signal
1092	Cardiogenic Shock	50	0.7	0.7	no signal
1093	Leukaemia	33	0.7	0.7	no signal
1094	Death	3,006	0.7	0.7	no signal
1095	Injection Site Bruising	275	0.7	0.7	no signal
1096	Haemorrhage Intracranial	52	0.7	0.7	no signal
1097	Intentional Product Misuse	301	0.7	0.7	no signal
1098	Therapeutic Response Unexpected	156	0.7	0.7	no signal
1099	Cardiac Arrest	285	0.7	0.7	no signal
1100	Restlessness	126	0.7	0.7	no signal
1101	Hepatic Encephalopathy	32	0.7	0.7	no signal
1102	Eyelid Oedema	40	0.7	0.7	no signal
1103	Ventricular Fibrillation	38	0.7	0.7	no signal
1104	Covid-19	601	0.7	0.7	no signal
1105	Disturbance In Attention	183	0.7	0.7	no signal
1106	Hepatic Failure	102	0.7	0.7	no signal
1107	Blood Glucose Fluctuation	37	0.7	0.7	no signal
1108	Blood Glucose Increased	635	0.7	0.7	no signal
1109	Crying	122	0.7	0.7	no signal
1110	Peritonitis	69	0.7	0.7	no signal
1111	Metabolic Acidosis	105	0.7	0.7	no signal
1112	Paranoia	57	0.7	0.7	no signal
1113	Dry Skin	429	0.7	0.7	no signal
1114	Blood Glucose Decreased	157	0.7	0.7	no signal
1115	Dialysis	46	0.7	0.7	no signal
1116	Internal Haemorrhage	37	0.7	0.7	no signal
1117	Sedation	84	0.7	0.7	no signal
1118	Product Dose Omission Issue	913	0.7	0.7	no signal
1119	Skin Haemorrhage	46	0.7	0.7	no signal
1120	Cytomegalovirus Infection	53	0.7	0.7	no signal
1121	Skin Fissures	60	0.7	0.7	no signal
1122	Injection Site Swelling	240	0.7	0.7	no signal
1123	Acute Myeloid Leukaemia	49	0.7	0.7	no signal
1124	Metastases To Central Nervous System	40	0.7	0.7	no signal
1125	Pneumocystis Jirovecii Pneumonia	31	0.6	0.6	no signal
1126	Hypotonia	31	0.6	0.6	no signal
1127	Multiple Sclerosis Relapse	212	0.6	0.6	no signal
1128	Apathy	44	0.6	0.6	no signal
1129	Product Packaging Issue	28	0.6	0.6	no signal
1130	Muscle Rigidity	36	0.6	0.6	no signal
1131	Meningioma	44	0.6	0.6	no signal
1132	Therapy Interrupted	206	0.6	0.6	no signal
1133	Drug Effect Incomplete	110	0.6	0.6	no signal
1134	Vaginal Haemorrhage	127	0.6	0.6	no signal
1135	Injection Site Pain	903	0.6	0.6	no signal
1136	Hypothermia	30	0.6	0.6	no signal
1137	Hypertensive Crisis	33	0.6	0.6	no signal
1138	Nightmare	102	0.6	0.6	no signal
1139	Therapy Change	28	0.6	0.6	no signal
1140	Hunger	39	0.6	0.6	no signal
1141	Oesophageal Carcinoma	87	0.6	0.6	no signal
1142	Personality Change	27	0.6	0.6	no signal
1143	Incorrect Dose Administered	648	0.6	0.6	no signal
1144	Hallucination, Auditory	45	0.6	0.6	no signal
1145	Psychotic Disorder	83	0.6	0.6	no signal
1146	Suicidal Ideation	254	0.6	0.6	no signal
1147	Erectile Dysfunction	71	0.6	0.6	no signal
1148	Seizure	314	0.6	0.6	no signal
1149	Injection Site Induration	35	0.6	0.6	no signal
1150	Angioedema	119	0.6	0.6	no signal
1151	Neutrophil Count Decreased	109	0.6	0.6	no signal
1152	Injection Site Warmth	55	0.6	0.6	no signal
1153	Electrocardiogram Qt Prolonged	95	0.6	0.6	no signal
1154	Febrile Neutropenia	174	0.5	0.5	no signal
1155	Intentional Drug Misuse	55	0.5	0.5	no signal
1156	Brain Injury	26	0.5	0.5	no signal
1157	Drug Dispensing Error	40	0.5	0.5	no signal
1158	Psychomotor Hyperactivity	43	0.5	0.5	no signal
1159	Toxic Skin Eruption	26	0.5	0.5	no signal
1160	Neutropenia	348	0.5	0.5	no signal
1161	Mood Altered	69	0.5	0.5	no signal
1162	Gastric Cancer	65	0.5	0.5	no signal
1163	Brain Oedema	32	0.5	0.5	no signal
1164	Drug Prescribing Error	49	0.5	0.5	no signal
1165	Disease Progression	295	0.5	0.5	no signal
1166	Product Availability Issue	56	0.5	0.5	no signal
1167	Mania	41	0.5	0.5	no signal
1168	No Adverse Event	432	0.5	0.5	no signal
1169	Irritability	146	0.5	0.5	no signal
1170	Anger	82	0.5	0.5	no signal
1171	Product Physical Issue	48	0.5	0.5	no signal
1172	Plasma Cell Myeloma	94	0.5	0.5	no signal
1173	Drug Ineffective For Unapproved Indication	133	0.5	0.5	no signal
1174	Abnormal Behaviour	95	0.5	0.5	no signal
1175	Glycosylated Haemoglobin Increased	60	0.5	0.5	no signal
1176	Device Dislocation	103	0.5	0.5	no signal
1177	Therapeutic Response Shortened	75	0.5	0.5	no signal
1178	Brain Fog	34	0.5	0.5	no signal
1179	Sexual Dysfunction	27	0.5	0.5	no signal
1180	Product Substitution Issue	133	0.5	0.5	no signal
1181	Respiratory Arrest	64	0.5	0.5	no signal
1182	Pain Of Skin	62	0.5	0.5	no signal
1183	Respiratory Depression	28	0.5	0.5	no signal
1184	Palmar-plantar Erythrodysaesthesia Syndrome	53	0.5	0.5	no signal
1185	Injection Site Mass	83	0.5	0.5	no signal
1186	Cholestasis	43	0.5	0.5	no signal
1187	Hyperbilirubinaemia	23	0.5	0.5	no signal
1188	Device Occlusion	31	0.5	0.5	no signal
1189	Injection Site Discomfort	23	0.5	0.5	no signal
1190	Rebound Effect	25	0.5	0.5	no signal
1191	Device Malfunction	148	0.5	0.5	no signal
1192	Gastrointestinal Carcinoma	20	0.5	0.5	no signal
1193	Affect Lability	21	0.5	0.5	no signal
1194	Mood Swings	69	0.5	0.5	no signal
1195	Product Prescribing Error	51	0.4	0.4	no signal
1196	Pancreatic Carcinoma	60	0.4	0.4	no signal
1197	Injection Site Urticaria	50	0.4	0.4	no signal
1198	Prostate Cancer	167	0.4	0.4	no signal
1199	Diabetic Ketoacidosis	49	0.4	0.4	no signal
1200	Device Defective	33	0.4	0.4	no signal
1201	Myocarditis	23	0.4	0.4	no signal
1202	Acute Hepatic Failure	27	0.4	0.4	no signal
1203	Acne	151	0.4	0.4	no signal
1204	Expired Product Administered	65	0.4	0.4	no signal
1205	Extrapyramidal Disorder	49	0.4	0.4	no signal
1206	Cytopenia	23	0.4	0.4	no signal
1207	Malignant Neoplasm Progression	194	0.4	0.4	no signal
1208	Aggression	95	0.4	0.4	no signal
1209	Neuroleptic Malignant Syndrome	22	0.4	0.4	no signal
1210	Dystonia	36	0.4	0.4	no signal
1211	Application Site Erythema	48	0.4	0.4	no signal
1212	Hereditary Angioedema	19	0.4	0.4	no signal
1213	Skin Irritation	83	0.4	0.4	no signal
1214	Exposure Via Skin Contact	40	0.4	0.4	no signal
1215	Neoplasm Progression	62	0.4	0.4	no signal
1216	Application Site Pruritus	40	0.4	0.4	no signal
1217	Hepatocellular Injury	25	0.4	0.4	no signal
1218	Tardive Dyskinesia	50	0.4	0.4	no signal
1219	Thrombotic Microangiopathy	17	0.4	0.4	no signal
1220	Poisoning	22	0.4	0.4	no signal
1221	Inability To Afford Medication	17	0.4	0.4	no signal
1222	Application Site Pain	38	0.4	0.4	no signal
1223	Anaphylactic Shock	44	0.4	0.4	no signal
1224	Drug Administered At Inappropriate Site	18	0.4	0.4	no signal
1225	Extra Dose Administered	66	0.3	0.3	no signal
1226	Product Packaging Quantity Issue	18	0.3	0.3	no signal
1227	Drug Effect Less Than Expected	23	0.3	0.3	no signal
1228	Gynaecomastia	48	0.3	0.3	no signal
1229	Generalised Tonic-clonic Seizure	25	0.3	0.3	no signal
1230	Lactic Acidosis	49	0.3	0.3	no signal
1231	Wrong Technique In Product Usage Process	305	0.3	0.3	no signal
1232	Menorrhagia	30	0.3	0.3	no signal
1233	Incorrect Product Storage	20	0.3	0.3	no signal
1234	Device Issue	130	0.3	0.3	no signal
1235	Drug Dependence	242	0.3	0.3	no signal
1236	Multiple Organ Dysfunction Syndrome	41	0.3	0.3	no signal
1237	Metrorrhagia	25	0.3	0.3	no signal
1238	Product Prescribing Issue	29	0.3	0.3	no signal
1239	Toxicity To Various Agents	239	0.3	0.3	no signal
1240	Withdrawal Syndrome	60	0.3	0.3	no signal
1241	Incorrect Route Of Drug Administration	51	0.3	0.3	no signal
1242	Circumstance Or Information Capable Of Leading To Medication Error	47	0.3	0.3	no signal
1243	Needle Issue	40	0.3	0.3	no signal
1244	Abnormal Weight Gain	17	0.3	0.3	no signal
1245	Euphoric Mood	14	0.3	0.3	no signal
1246	Injury Associated With Device	27	0.3	0.3	no signal
1247	Status Epilepticus	15	0.3	0.3	no signal
1248	Product Complaint	33	0.3	0.3	no signal
1249	Bladder Cancer	77	0.3	0.3	no signal
1250	Product Taste Abnormal	17	0.3	0.3	no signal
1251	Application Site Rash	17	0.3	0.3	no signal
1252	Drug Resistance	31	0.3	0.3	no signal
1253	Product Dispensing Error	26	0.2	0.2	no signal
1254	Drug Withdrawal Syndrome	106	0.2	0.2	no signal
1255	Product Odour Abnormal	12	0.2	0.2	no signal
1256	Posterior Reversible Encephalopathy Syndrome	11	0.2	0.2	no signal
1257	Application Site Irritation	14	0.2	0.2	no signal
1258	Skin Burning Sensation	80	0.2	0.2	no signal
1259	Product Administered At Inappropriate Site	20	0.2	0.2	no signal
1260	Akathisia	15	0.2	0.2	no signal
1261	Amenorrhoea	18	0.2	0.2	no signal
1262	Dysmenorrhoea	14	0.2	0.2	no signal
1263	Abortion Induced	10	0.2	0.2	no signal
1264	Dermatitis Atopic	52	0.2	0.2	no signal
1265	Device Delivery System Issue	27	0.2	0.2	no signal
1266	Hepatic Cancer	25	0.2	0.2	no signal
1267	Suicide Attempt	60	0.2	0.2	no signal
1268	Device Use Issue	17	0.2	0.2	no signal
1269	Drug Reaction With Eosinophilia And Systemic Symptoms	25	0.2	0.2	no signal
1270	Device Leakage	41	0.2	0.2	no signal
1271	Product Preparation Error	20	0.2	0.2	no signal
1272	Cytokine Release Syndrome	18	0.2	0.2	no signal
1273	Neurotoxicity	16	0.2	0.2	no signal
1274	Schizophrenia	11	0.2	0.2	no signal
1275	Drug Exposure During Pregnancy	31	0.2	0.2	no signal
1276	Peritonitis Bacterial	9	0.2	0.2	no signal
1277	Accidental Exposure To Product	89	0.2	0.2	no signal
1278	Drug Effective For Unapproved Indication	26	0.2	0.2	no signal
1279	Product Storage Error	76	0.2	0.2	no signal
1280	Device Deployment Issue	10	0.2	0.2	no signal
1281	Sickle Cell Anaemia With Crisis	13	0.2	0.2	no signal
1282	Syringe Issue	14	0.2	0.2	no signal
1283	Renal Cancer	38	0.2	0.2	no signal
1284	Poor Quality Product Administered	8	0.2	0.2	no signal
1285	Wrong Technique In Device Usage Process	35	0.2	0.2	no signal
1286	Incorrect Dose Administered By Device	18	0.1	0.1	no signal
1287	Product Adhesion Issue	25	0.1	0.1	no signal
1288	Mydriasis	9	0.1	0.1	no signal
1289	Intentional Self-injury	14	0.1	0.1	no signal
1290	Device Use Error	23	0.1	0.1	no signal
1291	Completed Suicide	55	0.1	0.1	no signal
1292	Device Difficult To Use	40	0.1	0.1	no signal
1293	Menstruation Irregular	16	0.1	0.1	no signal
1294	Device Mechanical Issue	7	0.1	0.1	no signal
1295	Drug Abuse	42	0.1	0.1	no signal
1296	Complication Of Device Insertion	9	0.1	0.1	no signal
1297	Drug Dose Omission By Device	37	0.1	0.1	no signal
1298	Intentional Overdose	30	0.1	0.1	no signal
1299	Haematotoxicity	4	0.1	0.1	no signal
1300	Caesarean Section	5	0.1	0.1	no signal
1301	Abortion Spontaneous	17	0.1	0.1	no signal
1302	Genital Haemorrhage	5	0.1	0.1	no signal
1303	Premature Delivery	6	0.1	0.1	no signal
1304	Premature Baby	11	0.1	0.1	no signal
1305	Myelosuppression	12	0.1	0.1	no signal
1306	Unintentional Medical Device Removal	4	0.1	0.1	no signal
1307	Hepatic Cytolysis	4	0.1	0.1	no signal
1308	Sopor	4	0.1	0.1	no signal
1309	Complication Of Device Removal	5	0.1	0.1	no signal
1310	Dependence	16	0.1	0.1	no signal
1311	Accidental Underdose	4	0.1	0.1	no signal
1312	Colorectal Cancer	11	0.0	0.0	no signal
1313	Device Adhesion Issue	3	0.0	0.0	no signal