Reaction

Stress Fracture reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,361 reports · 112 co-occurring drugs

As of the last recalculation, Stress Fracture appears in 5,361 FAERS reports alongside 112 co-occurring drug terms. The strongest observed disproportionality signal is ALENDRONATE SODIUM (PRR 136.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Alendronate Sodium	2,142	136.6	139.5
Risedronate Sodium	422	57.1	57.9
Alendronate Sodium Tablet	87	18.5	18.6
Asfotase Alfa	36	14.0	14.1
Zoledronic Acid	130	12.9	12.9
Raloxifene Hydrochloride	45	12.1	12.1
Ascorbic Acid	51	8.6	8.6
Vitamin E	64	8.0	8.0
Estrogens, Conjugated	111	7.4	7.4
Denosumab	361	7.3	7.4
Conjugated Estrogens	108	7.3	7.3
Teriparatide	205	7.3	7.3
Antacid	80	6.6	6.6
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	17	6.6	6.6
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	15	6.5	6.5
Calcium Carbonate	108	6.4	6.4
Calcium	225	6.1	6.1
Cimetidine	14	5.7	5.7
Salmeterol Xinafoate	11	5.0	5.0
Ezetimibe And Simvastatin	18	4.6	4.6
Emtricitabine And Tenofovir Alafenamide	13	4.5	4.5
Rabeprazole Sodium	31	4.4	4.4
Tenofovir Disoproxil Fumarate	37	4.4	4.4
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	20	4.3	4.3
Calcitriol Capsules 0.25 Mcg	22	4.3	4.3
Calcitriol Capsules 0.5 Mcg	22	4.3	4.3
Hyoscyamine Sulfate	10	4.2	4.2
Calcitriol	22	4.2	4.2
Doxepin	11	4.2	4.2
Meperidine Hydrochloride	10	4.2	4.2
Niacin	12	4.0	4.0
Emtricitabine And Tenofovir Disoproxil Fumarate	46	3.9	3.9
Tolterodine Tartrate	9	3.9	3.9
Tizanidine Hydrochloride	18	3.9	3.9
Conjugated Estrogens And Medroxyprogesterone Acetate	23	3.8	3.8
Cyanocobalamin	32	3.8	3.8
Romosozumab-Aqqg	13	3.7	3.7
Abaloparatide	28	3.7	3.7
Doxepin Hydrochloride	12	3.7	3.7
Ergocalciferol	348	3.7	3.7
Hydroxychloroquine Sulfate	84	3.6	3.6
Abacavir Sulfate	9	3.6	3.6
Progesterone	21	3.6	3.6
Methocarbamol Tablets	15	3.5	3.5
Quinapril Hydrochloride	7	3.4	3.5
Primidone	9	3.4	3.4
Methocarbamol	20	3.4	3.4
Meclizine Hcl 12.5Mg	12	3.4	3.4
Meclizine Hcl 25Mg	12	3.4	3.4
Meclizine Hcl 12.5 Mg	12	3.4	3.4
Meclizine Hcl 25 Mg	12	3.4	3.4
Cephalexin	19	3.4	3.4
Benzonatate	14	3.3	3.3
Methotrexate Sodium	380	3.2	3.2
Leflunomide	85	3.2	3.2
Calcium, Magnesium, Potassium, And Sodium Oxybates	7	3.2	3.2
Lopinavir And Ritonavir	11	3.2	3.2
Methotrexate	327	3.1	3.1
Liothyronine Sodium	7	3.1	3.1
Levothyroxine Sodium	245	3.1	3.1
Celecoxib	103	3.1	3.1
Cyclobenzaprine	39	3.1	3.1
Cetirizine Hcl	7	3.0	3.0
Fluticasone Propionate And Salmeterol Xinafoate	45	2.9	2.9
Zidovudine	10	2.9	2.9
Mometasone Furoate	31	2.9	2.9
Atovaquone	6	2.9	2.9
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	22	2.8	2.8
Medroxyprogesterone Acetate	36	2.8	2.8
Extended Phenytoin Sodium	12	2.8	2.8
Meloxicam	41	2.8	2.8
Felodipine Extended-Release Tablets	8	2.7	2.7
Felodipine	8	2.7	2.7
Tenofovir Disoproxil Fumarate Tablets	6	2.7	2.7
Esomeprazole Magnesium	159	2.7	2.7
Rizatriptan Benzoate	7	2.7	2.7
Testosterone	16	2.7	2.7
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	34	2.6	2.7
Tocilizumab	77	2.6	2.6
Terbinafine Hydrochloride	6	2.6	2.6
Estradiol	57	2.6	2.6
Fish Oil	59	2.6	2.6
Upadacitinib	53	2.5	2.5
Hydroxychloroquine	48	2.5	2.5
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	13	2.5	2.5
Naproxen Sodium, Pseudoephedrine Hydrochloride	13	2.5	2.5
Iron Sucrose	6	2.4	2.4
Fondaparinux Sodium	5	2.4	2.4
Lamivudine	19	2.4	2.4
Olmesartan Medoxomil	22	2.4	2.4
Abatacept	78	2.2	2.2
Dolutegravir Sodium	5	2.2	2.2
Lamivudine Oral	14	2.2	2.2
Loratadine And Pseudoephedrine Sulfate	4	2.0	2.0
Acetaminophen And Codeine	6	1.9	1.9
Tofacitinib	89	1.9	1.9
Fluticasone Propionate And Salmeterol	20	1.9	1.9
Golimumab	41	1.9	1.9
Travoprost	4	1.8	1.8
Cannabidiol	10	1.7	1.7
Acetaminophen, Aspirin (Nsaid) And Caffeine	7	1.6	1.6
Ruxolitinib	28	1.5	1.5
Ocrelizumab	24	1.5	1.5
Pegvaliase-Pqpz	3	1.4	1.4
Acetaminophen, Aspirin, And Caffeine	7	1.3	1.3
Emicizumab	4	1.3	1.3
Guselkumab	11	1.2	1.2
Risankizumab-Rzaa	25	1.2	1.2
Etanercept	182	1.2	1.2
Certolizumab Pegol	34	1.1	1.1
Isotretinoin	13	1.0	1.0
Cinacalcet Hydrochloride	6	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.