Reaction

Anti-Cyclic Citrullinated Peptide Antibody Positive reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,015 reports · 213 co-occurring drugs

As of the last recalculation, Anti-Cyclic Citrullinated Peptide Antibody Positive appears in 7,015 FAERS reports alongside 213 co-occurring drug terms. The strongest observed disproportionality signal is DESOXIMETASONE (PRR 3,739.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Desoximetasone	5,430	3,739.1	5,241.3
Cortisone Acetate	3,897	2,105.9	3,085.0
Pseudoephedrine Hydrochloride	3,542	2,064.9	3,160.5
Pseudoephedrine Hcl	3,575	1,962.1	2,912.3
Leflunomide	6,127	1,365.5	1,450.9
Sulfasalazine	5,597	1,046.1	1,127.1
Cetirizine Hydrochloride Allergy	4,174	1,008.3	1,170.4
Cetirizine Hydrochloride Tablets	4,174	1,008.2	1,170.2
Tocilizumab	5,915	975.5	1,029.2
Cetirizine	5,438	921.5	991.3
Tofacitinib Citrate	2,521	890.0	1,103.2
Diclofenac	5,519	887.7	948.8
Diclofenac Potassium, Film Coated	1,727	807.5	1,017.3
Diclofenac Potassium Tablets	1,727	806.9	1,016.3
Golimumab	5,397	806.2	860.6
Diclofenac Sodium 1%	3,987	765.9	862.6
Diclofenac Sodium Topical	3,987	765.8	862.5
Diclofenac Sodium Topical Gel, 1%	3,987	764.3	860.6
Certolizumab Pegol	5,583	688.5	723.1
Alendronate Sodium	5,368	669.0	706.8
Diclofenac Potassium	1,728	629.2	749.6
Diclofenac Sodium	5,583	535.4	556.1
Abatacept	5,434	513.1	534.2
Chlorhexidine Gluconate	1,260	498.5	578.6
Hydroxychloroquine Sulfate	4,768	482.7	509.4
Sarilumab	2,582	458.4	508.3
Naproxen Sodium Tablet, Coated	1,604	455.4	516.8
Naproxen Sodium, Coated Tablets	1,604	455.4	516.8
Naproxen Sodium 220Mg	1,604	454.7	516.0
Rituximab	5,755	445.1	457.7
Cetirizine Hydrochloride	5,442	433.3	448.1
Infliximab	5,687	403.9	414.8
Acetaminophen And Codeine	1,334	400.9	450.4
Tofacitinib	5,287	342.1	352.3
Folic Acid	5,560	315.2	322.4
Adalimumab-Adaz	3,029	299.0	317.2
Hydroxychloroquine	3,547	284.1	298.3
Adalimumab-Fkjp	2,719	283.8	301.5
Methotrexate Sodium	6,113	283.5	287.1
Adalimumab-Aaty	2,718	277.5	294.5
Cetiirizine	2,391	253.6	268.8
Calcium Gluconate	850	238.0	256.1
Methotrexate	5,824	237.0	240.3
Ustekinumab	3,572	210.0	217.6
Hydrocortisone Acetate	2,775	186.8	194.2
Botulinum Toxin Type A	689	182.5	193.2
Adalimumab	5,985	165.1	166.5
Prednisone	5,618	162.4	164.3
Quetiapine Fumarate	1,262	154.5	161.4
Oxycodone And Acetaminophen Tablets	517	138.9	145.1
Acetaminophen Tablet Extended Release	4,399	135.5	137.9
Pain Reliever	4,399	135.5	137.8
Acetaminophen 500Mg	4,399	135.4	137.8
Minocycline	491	134.3	140.2
Isopropyl Alcohol	1,232	131.0	135.9
Aprepitant	718	128.4	133.6
Etanercept	5,504	123.0	124.2
Hydrocortisone	2,421	122.4	125.8
Hydrocortisone Sodium Succinate	364	121.1	126.0
Pantoprazole Sodium In 0.9% Sodium Chloride	1,820	117.3	120.8
Pantoprazole Sodium Injection	1,820	117.3	120.8
Triamcinolone Acetonide Ointment Usp, 0.05%	813	116.4	120.6
Risedronate Sodium	1,031	115.2	119.1
Alcohol	1,231	113.9	117.6
Fosaprepitant Dimeglumine	482	111.6	115.6
Anti-Itch	1,732	101.5	104.1
Anti-Pruritic	1,732	101.5	104.1
Antipruritic (Anti-Itch)	1,732	101.5	104.1
Cool Relief Gel With Aloe	1,732	101.5	104.1
Drs. Hydrocortisone	1,732	101.5	104.1
Hydrocortisone Continuous Spray	1,732	101.5	104.1
Hydrocortisone Spray	1,732	101.5	104.1
Anti-Itch Cream	1,732	101.4	104.1
Hydrocortisone Lotion	1,732	101.4	104.1
Hydrocortisone Cream 1%	1,732	101.4	104.1
Hydrocortisone Cream 1/2%	1,732	101.4	104.1
Hydrocortisone 1%	1,732	101.3	104.0
Hydrocortisone Cream	1,732	100.9	103.6
Diltiazem Hydrochloride Extended-Release Tablets	367	100.9	104.3
Secukinumab	2,901	90.3	91.9
Antacid	1,185	88.9	91.1
Triamcinolone Acetonide	813	88.2	90.6
Acetaminophen	4,606	87.0	87.9
Doxyclycline Hyclate	463	86.3	88.7
Candesartan	897	85.4	87.6
Oxycodone	3,058	85.3	86.7
Tramadol Hydrochloride	924	83.7	85.8
Methylprednisolone Sodium Succinate	1,103	83.5	85.5
Calcium Carbonate	1,461	81.3	83.0
Naproxen	1,573	76.3	77.9
Naproxen Sodium	2,416	76.0	77.3
Oxycodone And Acetaminophen	519	71.3	72.9
Ibuprofen Capsule	2,632	62.1	62.9
Ibuprofen Tablet, Film Coated	2,632	62.1	62.9
Ibupfrofen	2,632	62.1	62.9
Ibuprofen Tablets Usp, 200Mg	2,632	62.1	62.9
Ibuprofen Oral	2,632	62.0	62.9
Ibuprofen Capsules 200 Mg	2,632	62.0	62.8
Ibuprofen 200 Mg	2,632	62.0	62.8
Ibuprofen 200Mg	2,632	62.0	62.8
Pantoprazole	3,010	61.1	61.8
Ramipril	1,876	61.0	61.9
Apremilast	2,094	60.1	61.0
Erenumab-Aooe	961	59.8	60.9
Vitamin C	1,457	59.1	60.1
Celecoxib	1,905	58.6	59.4
Tretinoin	155	57.9	59.0
Diphenhydramine Hydrochloride Capsule, Liquid Filled	392	57.6	58.7
Mirabegron	629	52.9	53.8
Mepolizumab	749	50.0	50.7
Atomoxetine Hydrochloride	378	49.8	50.5
Pantoprazole Sodium	1,821	48.9	49.5
Ibuprofen	2,716	47.8	48.3
Methylprednisolone Acetate	124	46.8	47.5
Doxycycline Hyclate	919	46.3	47.0
Doxycycline	919	45.8	46.5
Ascorbic Acid	337	45.1	45.8
Thiamine Hydrochloride	168	41.0	41.6
Azathioprine	1,037	40.8	41.3
Anakinra	211	38.9	39.4
Erythromycin	221	36.1	36.5
Alendronate Sodium Tablet	215	35.5	35.9
Sulfamethoxazole And Trimethoprim	873	34.9	35.3
Quetiapine	1,719	34.8	35.1
Magnesium	826	33.7	34.0
Diltiazem Hydrochloride	367	33.2	33.5
Methylprednisolone	1,230	31.8	32.1
Meloxicam	571	31.7	32.0
Fish Oil	817	30.2	30.5
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	1,323	30.0	30.3
Moxifloxacin Hydrochloride	196	29.5	29.8
Cyanocobalamin	302	28.4	28.6
Trimethoprim	110	28.1	28.4
Moxifloxacin	127	27.2	27.5
Mycophenolate Mofetil Hydrochloride	1,064	27.2	27.4
Lorazepam	1,337	27.0	27.2
Mycophenolate Mofetil	1,050	26.8	27.0
Topiramate	707	24.9	25.1
Buprenorphine	677	23.9	24.1
Lansoprazole	1,194	23.8	23.9
Ergocalciferol	2,152	23.5	23.6
Indomethacin	98	22.2	22.4
Calcium	961	22.1	22.2
Oxycodone Hydrochloride	1,271	21.0	21.1
Oxycodone Hydrochloride And Acetaminophen	615	20.1	20.3
Lamotrigine	792	20.0	20.1
Lisinopril	1,411	16.9	16.9
Vedolizumab	426	15.6	15.6
Human Immunoglobulin G	103	15.0	15.1
Cyclobenzaprine	240	14.7	14.8
Icosapent Ethyl	42	14.7	14.8
Prednisolone	785	14.4	14.5
Prednisolone Oral	785	14.4	14.5
Prednisolone Oral Solution	785	14.4	14.5
Mesalamine	256	14.0	14.1
Levothyroxine Sodium Anhydrous	444	14.0	14.0
Magnesium Hydroxide	59	13.1	13.1
Ranitidine Hydrochloride	231	13.0	13.1
Morphine	295	12.2	12.2
Fluticasone Furoate	45	11.1	11.1
Diphenhydramine Hydrochloride	544	10.5	10.5
Metformin Hydrochloride Tablets	196	10.4	10.4
Metformin Hydrochloride Extended-Release Tablets	196	10.4	10.4
Metformin Hydrochloride Tablet	196	10.4	10.4
Lamotirigine	240	10.3	10.3
Lamotrigine Extended-Release	240	10.3	10.3
Lamotrigine Chewable Dispersible	240	10.3	10.3
Pregabalin	838	10.2	10.3
Metformin Hydrochloride	196	10.1	10.1
Fluticasone Propionate Nasal	99	9.8	9.8
Zinc	78	9.5	9.5
Zinc Chloride	78	9.4	9.4
Hydromorphone Hydrochloride	275	9.2	9.2
Bupropion Hydrochloride	294	9.2	9.2
Dexamethasone Sodium Phosphate	31	9.1	9.1
Bupropion	134	9.1	9.1
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	91	9.0	9.0
Cyclobenzaprine Hydrochloride	27	8.9	9.0
Zinc Gluconate	78	8.9	9.0
Diphenhydramine	149	7.1	7.1
Ibuprofen Sodium	96	6.7	6.7
Morphine Sulfate	266	6.7	6.7
Ibuprofen Tablets, Coated	90	6.3	6.4
Prednisolone Acetate	22	6.3	6.3
Candesartan Cilexetil	50	5.7	5.7
Ranitidine	361	5.6	5.6
Albuterol	207	5.2	5.2
Fluticasone Propionate	210	4.9	4.9
Levothyroxine Sodium	472	4.7	4.7
Telmisartan	28	4.7	4.7
Upadacitinib	115	4.2	4.2
Cyclosporine	156	4.2	4.2
Dexamethasone 1.5 Mg	380	4.0	4.0
Trazodone Hydrochloride	21	4.0	4.0
Dexamethasone	380	4.0	4.0
Meperidine Hydrochloride	12	3.9	3.9
Leucovorin Calcium	23	3.6	3.6
Canagliflozin	33	3.3	3.3
Ciclesonide	15	3.3	3.3
Salicylic Acid	57	3.2	3.2
Albuterol Sulfate	301	3.1	3.1
Bupivacaine	9	2.9	2.9
Cetirizine Hcl	8	2.6	2.6
Infliximab-Dyyb	25	2.5	2.5
Rosuvastatin Calcium	24	2.5	2.5
Methocarbamol Tablets	12	2.1	2.1
Metformin	250	2.1	2.1
Rifampin	8	1.6	1.6
Levocetirizine Dihydrochloride	12	1.5	1.5
Orlistat	11	1.3	1.3
Canakinumab	4	1.1	1.1
Onabotulinumtoxina	27	1.0	1.0
Varenicline Tartrate	23	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.